KR101997018B1 - 글리코겐-기반 양이온 폴리머 - Google Patents

글리코겐-기반 양이온 폴리머 Download PDF

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KR101997018B1
KR101997018B1 KR1020147021215A KR20147021215A KR101997018B1 KR 101997018 B1 KR101997018 B1 KR 101997018B1 KR 1020147021215 A KR1020147021215 A KR 1020147021215A KR 20147021215 A KR20147021215 A KR 20147021215A KR 101997018 B1 KR101997018 B1 KR 101997018B1
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alkyl
amino
group
glycogen
polymer
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KR20150006414A (ko
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빈첸초 루소
엘리자 리베라티
니콜라 카졸라
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아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/18—Reserve carbohydrates, e.g. glycogen, inulin, laminarin; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
KR1020147021215A 2012-03-15 2013-02-21 글리코겐-기반 양이온 폴리머 Expired - Fee Related KR101997018B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12159710 2012-03-15
EP12159710.8 2012-03-15
PCT/EP2013/053422 WO2013135471A1 (en) 2012-03-15 2013-02-21 Glycogen-based cationic polymers

Publications (2)

Publication Number Publication Date
KR20150006414A KR20150006414A (ko) 2015-01-16
KR101997018B1 true KR101997018B1 (ko) 2019-07-05

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US (1) US9717801B2 (https=)
EP (1) EP2825565B1 (https=)
JP (1) JP6247234B2 (https=)
KR (1) KR101997018B1 (https=)
CN (2) CN104080812B (https=)
AR (1) AR090307A1 (https=)
AU (1) AU2013231561B2 (https=)
BR (1) BR112014018617A8 (https=)
CA (1) CA2859273C (https=)
CY (1) CY1121829T1 (https=)
DK (1) DK2825565T3 (https=)
EA (1) EA032479B1 (https=)
ES (1) ES2732216T3 (https=)
GE (1) GEP201606581B (https=)
HR (1) HRP20191114T1 (https=)
HU (1) HUE045049T2 (https=)
IL (1) IL233823B (https=)
LT (1) LT2825565T (https=)
ME (1) ME03429B (https=)
MX (1) MX351599B (https=)
PL (1) PL2825565T3 (https=)
PT (1) PT2825565T (https=)
RS (1) RS58985B1 (https=)
SG (2) SG11201403816YA (https=)
SI (1) SI2825565T1 (https=)
SM (1) SMT201900342T1 (https=)
TR (1) TR201909387T4 (https=)
UA (1) UA115135C2 (https=)
WO (1) WO2013135471A1 (https=)

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AR095937A1 (es) 2013-04-05 2015-11-25 Acraf Potenciador de la solubilidad en agua a base de glucógeno
BR112015027134A8 (pt) 2013-04-26 2019-12-24 Mirexus Biotechnologies Inc método e aditivo para mudar o comportamento reológico de uma formulação à base de água ou à base de álcool, composição e método para estabilizar uma formulação ou aumentar a fotoestabilidade de compostos orgânicos
BR112017014090A2 (pt) * 2014-12-29 2018-03-06 Bonac Corporation composição, e, métodos para produção de uma composição e estabilização de uma molécula de ácido nucleico.
CN104558246B (zh) * 2015-01-20 2017-03-01 武汉理工大学 一种叶酸/生物素修饰的壳聚糖材料及其制备方法
DE102015205088C5 (de) * 2015-03-20 2024-09-26 Kuka Deutschland Gmbh Verfahren zum Ermitteln eines Kalibrierungsparameters eines Fahrzeuges sowie Fahrzeug hierzu
JP6872782B2 (ja) * 2016-03-08 2021-05-19 国立大学法人京都大学 カチオン性グルカンナノスフェア、複合体、核酸導入剤及びがん治療剤
CN109310644A (zh) * 2016-04-14 2019-02-05 奇迹连结生物技术公司 包含植物糖原纳米颗粒的抗感染组合物
BR112018072452A2 (pt) * 2016-05-04 2019-02-19 Mirexus Biotechnologies Inc. nanopartículas de glicogênio e fitoglicogênio como compostos imunossupressores, e composições e métodos para uso dos mesmos
CN105949344B (zh) * 2016-05-13 2019-05-17 中山大学 一种阳离子超支化多糖衍生物及其在增强血卟啉类光敏剂对肿瘤细胞光毒性方面的应用
WO2019027999A1 (en) * 2017-07-31 2019-02-07 Ohio State Innovation Foundation BIOMIMETIC NANOMATERIALS AND USES THEREOF
US11384161B2 (en) 2018-01-11 2022-07-12 Virginia Tech Intellectual Properties, Inc. Amphiphilic polysaccharides, polysaccharide-based hydrogels, and methods of manufacture
CN116178587B (zh) * 2023-02-28 2025-04-11 江南大学 一种季铵盐化糖原、复合抗菌水凝胶及其制备方法与应用

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US20030147958A1 (en) 2002-01-29 2003-08-07 Cheol-Hee Ahn Biodegradable multi-block copolymers of poly(amino acid)s and poly(ethylene glycol) for the delivery of bioactive agents
US20030186916A1 (en) 2002-03-12 2003-10-02 Lei Yu Vector for transfection of eukaryotic cells
JPWO2005094894A1 (ja) 2004-03-31 2008-02-14 株式会社メドジェル 細胞に核酸を導入するための製剤
WO2007038769A1 (en) 2005-09-28 2007-04-05 Hetzel Adrian H Electro-hydraulic timed angle controlled joint simulation torque calibration, certification and analysis device
CN101235098A (zh) * 2008-01-09 2008-08-06 浙江大学 功能性植物多糖的修饰方法
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CN102068698A (zh) * 2009-11-24 2011-05-25 深圳先进技术研究院 纳米疫苗及其制备方法

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Also Published As

Publication number Publication date
ES2732216T3 (es) 2019-11-21
KR20150006414A (ko) 2015-01-16
WO2013135471A1 (en) 2013-09-19
CN104080812B (zh) 2017-06-27
ME03429B (me) 2020-01-20
LT2825565T (lt) 2019-07-10
SI2825565T1 (sl) 2019-08-30
SG10201607577QA (en) 2016-11-29
PT2825565T (pt) 2019-07-10
SG11201403816YA (en) 2014-08-28
BR112014018617A8 (pt) 2017-07-11
AU2013231561A1 (en) 2014-07-10
CN107236052A (zh) 2017-10-10
CY1121829T1 (el) 2020-07-31
UA115135C2 (uk) 2017-09-25
CA2859273A1 (en) 2013-09-19
MX351599B (es) 2017-10-20
BR112014018617A2 (https=) 2017-06-20
EA032479B1 (ru) 2019-06-28
CN104080812A (zh) 2014-10-01
AU2013231561B2 (en) 2017-06-08
TR201909387T4 (tr) 2019-07-22
EP2825565A1 (en) 2015-01-21
IL233823A0 (en) 2014-09-30
JP6247234B2 (ja) 2017-12-13
AR090307A1 (es) 2014-11-05
JP2015510020A (ja) 2015-04-02
HUE045049T2 (hu) 2019-12-30
RS58985B1 (sr) 2019-08-30
EP2825565B1 (en) 2019-04-03
GEP201606581B (en) 2016-11-25
DK2825565T3 (da) 2019-06-24
HK1203984A1 (en) 2015-11-06
CN107236052B (zh) 2019-09-24
PL2825565T3 (pl) 2019-10-31
US9717801B2 (en) 2017-08-01
MX2014010698A (es) 2015-03-10
US20140378532A1 (en) 2014-12-25
CA2859273C (en) 2020-04-14
EA201491613A1 (ru) 2014-12-30
HRP20191114T1 (hr) 2019-09-20
IL233823B (en) 2018-05-31
SMT201900342T1 (it) 2019-07-11

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