HRP20191114T1 - Kationski polimeri na bazi glikogena - Google Patents

Kationski polimeri na bazi glikogena Download PDF

Info

Publication number
HRP20191114T1
HRP20191114T1 HRP20191114TT HRP20191114T HRP20191114T1 HR P20191114 T1 HRP20191114 T1 HR P20191114T1 HR P20191114T T HRP20191114T T HR P20191114TT HR P20191114 T HRP20191114 T HR P20191114T HR P20191114 T1 HRP20191114 T1 HR P20191114T1
Authority
HR
Croatia
Prior art keywords
alkyl
alkylamino
group
alkylammonium
different
Prior art date
Application number
HRP20191114TT
Other languages
English (en)
Croatian (hr)
Inventor
Vincenzo Russo
Elisa Liberati
Nicola Cazzolla
Original Assignee
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. filed Critical Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
Publication of HRP20191114T1 publication Critical patent/HRP20191114T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/18Reserve carbohydrates, e.g. glycogen, inulin, laminarin; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HRP20191114TT 2012-03-15 2013-02-21 Kationski polimeri na bazi glikogena HRP20191114T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12159710 2012-03-15
PCT/EP2013/053422 WO2013135471A1 (en) 2012-03-15 2013-02-21 Glycogen-based cationic polymers
EP13704973.0A EP2825565B1 (en) 2012-03-15 2013-02-21 Glycogen-based cationic polymers

Publications (1)

Publication Number Publication Date
HRP20191114T1 true HRP20191114T1 (hr) 2019-09-20

Family

ID=47739282

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20191114TT HRP20191114T1 (hr) 2012-03-15 2013-02-21 Kationski polimeri na bazi glikogena

Country Status (29)

Country Link
US (1) US9717801B2 (https=)
EP (1) EP2825565B1 (https=)
JP (1) JP6247234B2 (https=)
KR (1) KR101997018B1 (https=)
CN (2) CN104080812B (https=)
AR (1) AR090307A1 (https=)
AU (1) AU2013231561B2 (https=)
BR (1) BR112014018617A8 (https=)
CA (1) CA2859273C (https=)
CY (1) CY1121829T1 (https=)
DK (1) DK2825565T3 (https=)
EA (1) EA032479B1 (https=)
ES (1) ES2732216T3 (https=)
GE (1) GEP201606581B (https=)
HR (1) HRP20191114T1 (https=)
HU (1) HUE045049T2 (https=)
IL (1) IL233823B (https=)
LT (1) LT2825565T (https=)
ME (1) ME03429B (https=)
MX (1) MX351599B (https=)
PL (1) PL2825565T3 (https=)
PT (1) PT2825565T (https=)
RS (1) RS58985B1 (https=)
SG (2) SG10201607577QA (https=)
SI (1) SI2825565T1 (https=)
SM (1) SMT201900342T1 (https=)
TR (1) TR201909387T4 (https=)
UA (1) UA115135C2 (https=)
WO (1) WO2013135471A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR095937A1 (es) 2013-04-05 2015-11-25 Acraf Potenciador de la solubilidad en agua a base de glucógeno
KR102214865B1 (ko) 2013-04-26 2021-02-15 마이렉서스 바이오테크놀로지스 인코퍼레이티드 파이토글리코겐 나노입자와 이를 제조하는 방법
CA2971830A1 (en) * 2014-12-29 2016-07-07 Bonac Corporation Composition containing nucleic acid molecule stably
CN104558246B (zh) * 2015-01-20 2017-03-01 武汉理工大学 一种叶酸/生物素修饰的壳聚糖材料及其制备方法
DE102015205088C5 (de) * 2015-03-20 2024-09-26 Kuka Deutschland Gmbh Verfahren zum Ermitteln eines Kalibrierungsparameters eines Fahrzeuges sowie Fahrzeug hierzu
JP6872782B2 (ja) * 2016-03-08 2021-05-19 国立大学法人京都大学 カチオン性グルカンナノスフェア、複合体、核酸導入剤及びがん治療剤
WO2017177342A1 (en) * 2016-04-14 2017-10-19 Mirexus Biotechnologies Inc. Anti-infective compositions comprising phytoglycogen nanoparticles
WO2017190248A1 (en) * 2016-05-04 2017-11-09 Mirexus Biotechnologies Inc. Glycogen and phytoglycogen nanoparticles as immunosuppressive compounds, and compositions and methods of use thereof
CN105949344B (zh) * 2016-05-13 2019-05-17 中山大学 一种阳离子超支化多糖衍生物及其在增强血卟啉类光敏剂对肿瘤细胞光毒性方面的应用
WO2019027999A1 (en) * 2017-07-31 2019-02-07 Ohio State Innovation Foundation BIOMIMETIC NANOMATERIALS AND USES THEREOF
US11384161B2 (en) 2018-01-11 2022-07-12 Virginia Tech Intellectual Properties, Inc. Amphiphilic polysaccharides, polysaccharide-based hydrogels, and methods of manufacture
CN116178587B (zh) * 2023-02-28 2025-04-11 江南大学 一种季铵盐化糖原、复合抗菌水凝胶及其制备方法与应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904370D0 (en) 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
IT1255488B (it) 1992-08-04 1995-11-06 Angelini Francesco Ist Ricerca Polisaccaridi del glicogeno
US7144713B1 (en) * 1995-10-02 2006-12-05 Emd Biosciences, Inc. Method for precipitating nucleic acid with visible carrier
GB9600272D0 (en) 1996-01-06 1996-03-06 Univ Nottingham Polymers
US6106858A (en) * 1997-09-08 2000-08-22 Skyepharma, Inc. Modulation of drug loading in multivescular liposomes
WO2002100435A1 (en) 2001-06-11 2002-12-19 Centre Hospitalier Universitaire De Montreal Compositions and methods for enhancing nucleic acid transfer into cells
US20030147958A1 (en) 2002-01-29 2003-08-07 Cheol-Hee Ahn Biodegradable multi-block copolymers of poly(amino acid)s and poly(ethylene glycol) for the delivery of bioactive agents
AU2003220161A1 (en) 2002-03-12 2003-09-29 Nitto Denko Corporation Vector for transfection of eukaryotic cells
WO2005094894A1 (ja) 2004-03-31 2005-10-13 Medgel Corporation 細胞に核酸を導入するための製剤
US8108158B2 (en) 2005-09-28 2012-01-31 Adrian H. Hetzel Electro-hydraulic timed angle controlled joint simulation torque calibration, certification and analysis device
UA97559C2 (uk) * 2007-11-08 2012-02-27 Оцука Фармасьютікал Ко., Лтд. Комплекс нуклеїнової кислоти і композиція для доставки нуклеїнової кислоти
CN101235098A (zh) * 2008-01-09 2008-08-06 浙江大学 功能性植物多糖的修饰方法
WO2010072627A1 (en) * 2008-12-22 2010-07-01 Unilever Plc Laundry compositions
BRPI0923570A2 (pt) * 2008-12-22 2016-08-23 Unilever Nv composição detergente líquida, e, método para proporcionar maciez a um artigo de tecido
EP2428578B1 (en) * 2009-05-08 2016-03-23 Ezaki Glico Co., Ltd. Glucuronic acid-containing glucan, process for production of same, and use of same
EP2275085A1 (en) * 2009-07-07 2011-01-19 University of Rostock Biodegradable copolymer suitable for delivering nucleic acid materials into cells
CN102068698A (zh) * 2009-11-24 2011-05-25 深圳先进技术研究院 纳米疫苗及其制备方法

Also Published As

Publication number Publication date
CN107236052B (zh) 2019-09-24
WO2013135471A1 (en) 2013-09-19
MX2014010698A (es) 2015-03-10
AR090307A1 (es) 2014-11-05
RS58985B1 (sr) 2019-08-30
IL233823A0 (en) 2014-09-30
SG10201607577QA (en) 2016-11-29
HK1203984A1 (en) 2015-11-06
PT2825565T (pt) 2019-07-10
BR112014018617A2 (https=) 2017-06-20
EA201491613A1 (ru) 2014-12-30
JP2015510020A (ja) 2015-04-02
CA2859273C (en) 2020-04-14
CN107236052A (zh) 2017-10-10
DK2825565T3 (da) 2019-06-24
EP2825565A1 (en) 2015-01-21
EA032479B1 (ru) 2019-06-28
EP2825565B1 (en) 2019-04-03
US9717801B2 (en) 2017-08-01
ME03429B (me) 2020-01-20
JP6247234B2 (ja) 2017-12-13
BR112014018617A8 (pt) 2017-07-11
IL233823B (en) 2018-05-31
SG11201403816YA (en) 2014-08-28
US20140378532A1 (en) 2014-12-25
SI2825565T1 (sl) 2019-08-30
GEP201606581B (en) 2016-11-25
CN104080812B (zh) 2017-06-27
AU2013231561B2 (en) 2017-06-08
KR20150006414A (ko) 2015-01-16
CY1121829T1 (el) 2020-07-31
UA115135C2 (uk) 2017-09-25
SMT201900342T1 (it) 2019-07-11
ES2732216T3 (es) 2019-11-21
LT2825565T (lt) 2019-07-10
HUE045049T2 (hu) 2019-12-30
CA2859273A1 (en) 2013-09-19
PL2825565T3 (pl) 2019-10-31
KR101997018B1 (ko) 2019-07-05
CN104080812A (zh) 2014-10-01
TR201909387T4 (tr) 2019-07-22
AU2013231561A1 (en) 2014-07-10
MX351599B (es) 2017-10-20

Similar Documents

Publication Publication Date Title
HRP20191114T1 (hr) Kationski polimeri na bazi glikogena
BR112013022001A2 (pt) lentes de contato de silicone-hidrogel dimensionalmente estáveis
HRP20171590T1 (hr) Polimeri koji vežu protone za oralnu primjenu
ES2723026T3 (es) Formas de sal de ácido de conjugados polímero-fármaco
AR110270A1 (es) Preparación de complejos sólidos de ciclodextrina para la administración de ingredientes farmacéuticos activos oftálmicos
HRP20211612T1 (hr) Polimerni sustavi za isporuku s dugim djelovanjem
AR112414A1 (es) Agonistas del receptor tipo toll 7 (tlr7) que tienen una porción benzotriazol, conjugados de estos y métodos y usos de estos
JP2014054250A5 (https=)
JP2011522070A5 (https=)
HRP20250339T1 (hr) Farmaceutski pripravak
BR112020013974A8 (pt) Formulação para administração de rna
AR079752A1 (es) Prodrogas de sales de amonio cuaternario
AR076421A1 (es) Eficiencia mejorada de composiciones de pantalla solar
RU2016138020A (ru) Композиции для введения phk в желудочно-кишечный тракт
AR099756A1 (es) Nanopartículas terapéuticas que comprenden un agente terapéutico, y métodos para su elaboración y uso, composición farmacéutica
JP2010535239A5 (https=)
JP2016523313A5 (https=)
SI2702992T1 (en) Use of melatonin for the treatment and / or prevention of mucositis
JP2012522818A5 (https=)
BR112015013485A2 (pt) derivados de benzilsulfonamida como moduladores de rorc
FI3528787T3 (fi) Farmaseuttisia formulaatioita ja menetelmiä niiden valmistamiseksi
BR112013032372A2 (pt) Composição de desemulsificante de poliorganosiloxano biodegradável e método para fabricação da mesma
BR112017027687A2 (pt) iniciadores de dilítio
BR112018011155A2 (pt) sais de amônio quaternário que contêm amida/éster com peso molecular ultrabaixo que têm caudas de hidrocarboneto curtas
NZ731309A (en) Buprenorphine dosing regimens