KR101960129B1 - 피롤로벤조디아제핀 - Google Patents

피롤로벤조디아제핀 Download PDF

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Publication number
KR101960129B1
KR101960129B1 KR1020147032595A KR20147032595A KR101960129B1 KR 101960129 B1 KR101960129 B1 KR 101960129B1 KR 1020147032595 A KR1020147032595 A KR 1020147032595A KR 20147032595 A KR20147032595 A KR 20147032595A KR 101960129 B1 KR101960129 B1 KR 101960129B1
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South Korea
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nme
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KR1020147032595A
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English (en)
Korean (ko)
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KR20150016245A (ko
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필립 윌슨 하워드
데이비드 서스턴
콘드아케르 미라주르 라만
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메디뮨 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020147032595A 2012-04-30 2013-04-30 피롤로벤조디아제핀 KR101960129B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261640310P 2012-04-30 2012-04-30
US61/640,310 2012-04-30
PCT/GB2013/051098 WO2013164593A1 (en) 2012-04-30 2013-04-30 Pyrrolobenzodiazepines

Publications (2)

Publication Number Publication Date
KR20150016245A KR20150016245A (ko) 2015-02-11
KR101960129B1 true KR101960129B1 (ko) 2019-03-19

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KR1020147032595A KR101960129B1 (ko) 2012-04-30 2013-04-30 피롤로벤조디아제핀

Country Status (15)

Country Link
US (1) US9376440B2 (zh)
EP (1) EP2855482B1 (zh)
JP (1) JP6157596B2 (zh)
KR (1) KR101960129B1 (zh)
CN (1) CN104684914B (zh)
AU (1) AU2013255613B2 (zh)
BR (1) BR112014027143B1 (zh)
CA (1) CA2871172C (zh)
ES (1) ES2623042T3 (zh)
HK (1) HK1208444A1 (zh)
IN (1) IN2014MN02092A (zh)
MX (1) MX369715B (zh)
NZ (1) NZ701290A (zh)
WO (1) WO2013164593A1 (zh)
ZA (1) ZA201407759B (zh)

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KR101961976B1 (ko) 2011-10-14 2019-03-25 시애틀 지네틱스, 인크. 피롤로벤조디아제핀 및 표적 접합체
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US9567340B2 (en) 2012-12-21 2017-02-14 Medimmune Limited Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases
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Also Published As

Publication number Publication date
CN104684914A (zh) 2015-06-03
NZ701290A (en) 2016-08-26
JP2015515972A (ja) 2015-06-04
MX2014013098A (es) 2015-04-14
BR112014027143B1 (pt) 2020-06-09
CA2871172C (en) 2020-08-25
MX369715B (es) 2019-11-20
EP2855482A1 (en) 2015-04-08
HK1208444A1 (zh) 2016-03-04
ZA201407759B (en) 2015-11-25
JP6157596B2 (ja) 2017-07-05
EP2855482B1 (en) 2017-03-01
CN104684914B (zh) 2017-12-15
IN2014MN02092A (zh) 2015-09-04
CA2871172A1 (en) 2013-11-07
WO2013164593A1 (en) 2013-11-07
US9376440B2 (en) 2016-06-28
KR20150016245A (ko) 2015-02-11
US20150133435A1 (en) 2015-05-14
AU2013255613B2 (en) 2017-06-22
AU2013255613A1 (en) 2014-11-13
BR112014027143A2 (pt) 2017-06-27
ES2623042T3 (es) 2017-07-10

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