KR101924665B1 - 회전-의존성 전사 서열분석 시스템 및 사용 방법 - Google Patents

회전-의존성 전사 서열분석 시스템 및 사용 방법 Download PDF

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KR101924665B1
KR101924665B1 KR1020137024640A KR20137024640A KR101924665B1 KR 101924665 B1 KR101924665 B1 KR 101924665B1 KR 1020137024640 A KR1020137024640 A KR 1020137024640A KR 20137024640 A KR20137024640 A KR 20137024640A KR 101924665 B1 KR101924665 B1 KR 101924665B1
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South Korea
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nucleic acid
tag
acid molecule
target nucleic
rna polymerase
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KR20140089308A (ko
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테오필로스 코트세로글로우
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이브 바이오메디컬, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
KR1020137024640A 2011-02-23 2012-02-23 회전-의존성 전사 서열분석 시스템 및 사용 방법 Expired - Fee Related KR101924665B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161463850P 2011-02-23 2011-02-23
US61/463,850 2011-02-23
US201161574270P 2011-07-30 2011-07-30
US61/574,270 2011-07-30
PCT/US2012/026339 WO2012116191A1 (en) 2011-02-23 2012-02-23 Rotation-dependent transcriptional sequencing systems and methods of using

Publications (2)

Publication Number Publication Date
KR20140089308A KR20140089308A (ko) 2014-07-14
KR101924665B1 true KR101924665B1 (ko) 2018-12-03

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Country Status (9)

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US (2) US8574840B2 (enExample)
EP (1) EP2678444B1 (enExample)
JP (1) JP6018092B2 (enExample)
KR (1) KR101924665B1 (enExample)
CN (1) CN103534357B (enExample)
AU (1) AU2012220546B2 (enExample)
CA (1) CA2827880A1 (enExample)
RU (1) RU2636460C2 (enExample)
WO (1) WO2012116191A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8775454B2 (en) 2008-07-29 2014-07-08 James L. Geer Phone assisted ‘photographic memory’
US9128981B1 (en) 2008-07-29 2015-09-08 James L. Geer Phone assisted ‘photographic memory’
JP6018092B2 (ja) 2011-02-23 2016-11-02 イブ バイオメディカル インコーポレイテッド 回転依存転写配列決定システムおよび使用方法
AU2014218911B2 (en) * 2013-02-20 2018-07-12 Eve Biomedical, Inc. Methods and compositions for nanostructure-based nucleic acid sequencing
US20160309068A1 (en) * 2014-01-06 2016-10-20 The Regents Of The University Of California Spatial frequency domain imaging using custom patterns
DK3460075T3 (da) 2014-07-15 2021-02-01 Illumina Inc Biokemisk aktiveret elektronisk anordning
SG11201708867UA (en) * 2015-04-30 2017-11-29 Curevac Ag Immobilized poly(n)polymerase
CN106991224A (zh) * 2017-03-27 2017-07-28 蔡彤� 一种芯片引线键合定位的建模方法及系统
US10344328B2 (en) 2017-11-17 2019-07-09 Ultima Genomics, Inc. Methods for biological sample processing and analysis
US11499962B2 (en) 2017-11-17 2022-11-15 Ultima Genomics, Inc. Methods and systems for analyte detection and analysis
US10957187B2 (en) * 2017-12-21 2021-03-23 Lumileds Llc Road lighting
US11798406B2 (en) * 2018-03-21 2023-10-24 Lumileds Llc Road lighting
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
US10512911B1 (en) 2018-12-07 2019-12-24 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
US12239980B2 (en) 2018-12-07 2025-03-04 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
US10852518B1 (en) 2019-03-14 2020-12-01 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US10900078B2 (en) 2019-03-14 2021-01-26 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US10830703B1 (en) 2019-03-14 2020-11-10 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US11118223B2 (en) 2019-03-14 2021-09-14 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis
US11609208B2 (en) 2019-04-12 2023-03-21 Western Digital Technologies, Inc. Devices and methods for molecule detection based on thermal stabilities of magnetic nanoparticles
CN113905822B (zh) * 2019-04-12 2023-09-22 西部数据技术公司 使用磁传感器阵列边合成边核酸测序
US11327073B2 (en) 2019-04-12 2022-05-10 Western Digital Technologies, Inc. Thermal sensor array for molecule detection and related detection schemes
US11112468B2 (en) 2019-04-12 2021-09-07 Western Digital Technologies, Inc. Magnetoresistive sensor array for molecule detection and related detection schemes
CN110376171B (zh) * 2019-07-15 2021-11-19 上海理工大学 应用于dPCR检测仪的透射式荧光检测成像系统
US11208682B2 (en) 2019-09-13 2021-12-28 Western Digital Technologies, Inc. Enhanced optical detection for nucleic acid sequencing using thermally-dependent fluorophore tags
US11060138B1 (en) 2020-01-17 2021-07-13 Element Biosciences, Inc. Nucleic acid sequencing systems
CN116802267A (zh) * 2020-10-23 2023-09-22 斯宾德尔生物科技公司 用于rna合成的组合物和方法
IL310281A (en) 2021-07-21 2024-03-01 Element Biosciences Inc Optical systems for nucleic acid sequencing and methods thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007111924A2 (en) * 2006-03-23 2007-10-04 The Board Of Trustees Of The Leland Stanford Junior University Motion resolved molecular sequencing

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693489A (en) 1984-03-30 1997-12-02 Associated Universities, Inc. Cloning and expression of the gene for bacteriophage T7 RNA polymerase
US6872816B1 (en) * 1996-01-24 2005-03-29 Third Wave Technologies, Inc. Nucleic acid detection kits
RU2143004C1 (ru) * 1993-09-27 1999-12-20 АРЧ Девелопмент Корпорейшн Способ определения последовательности нуклеиновой кислоты (варианты) и набор для использования при определении последовательности нуклеиновой кислоты
US6232075B1 (en) * 1998-12-14 2001-05-15 Li-Cor, Inc. Heterogeneous assay for pyrophosphate detection
US6982146B1 (en) * 1999-08-30 2006-01-03 The United States Of America As Represented By The Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
US6529240B2 (en) * 1999-11-18 2003-03-04 Agilent Technologies, Inc. Random access memory integrated with CMOS sensors
US6548264B1 (en) * 2000-05-17 2003-04-15 University Of Florida Coated nanoparticles
JP2008507952A (ja) * 2004-03-05 2008-03-21 リサーチ ファウンデーション オブ ステイト ユニヴァーシティー オブ ニューヨーク 情報依存性分子モーターとしてのｒｎａポリメラーゼの使用
US20070077575A1 (en) 2004-03-05 2007-04-05 Mcallister William T Use of rna polymerase as an information-dependent molecular motor
AU2008331824B2 (en) * 2007-12-04 2014-07-24 Pacific Biosciences Of California, Inc. Alternate labeling strategies for single molecule sequencing
US8815576B2 (en) 2007-12-27 2014-08-26 Lawrence Livermore National Security, Llc. Chip-based sequencing nucleic acids
JP6018092B2 (ja) 2011-02-23 2016-11-02 イブ バイオメディカル インコーポレイテッド 回転依存転写配列決定システムおよび使用方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007111924A2 (en) * 2006-03-23 2007-10-04 The Board Of Trustees Of The Leland Stanford Junior University Motion resolved molecular sequencing
US20080020392A1 (en) 2006-03-23 2008-01-24 Block Steven M Motion resolved molecular sequencing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Nature, Vol. 409, No. 6816, pp. 113-115 (2001.01.04.)*

Also Published As

Publication number Publication date
RU2636460C2 (ru) 2017-11-23
CA2827880A1 (en) 2012-08-30
US9657343B2 (en) 2017-05-23
CN103534357B (zh) 2016-05-18
CN103534357A (zh) 2014-01-22
EP2678444B1 (en) 2016-02-17
AU2012220546B2 (en) 2017-02-23
RU2013142965A (ru) 2015-03-27
EP2678444A1 (en) 2014-01-01
JP6018092B2 (ja) 2016-11-02
US8574840B2 (en) 2013-11-05
WO2012116191A1 (en) 2012-08-30
HK1187959A1 (zh) 2014-04-17
KR20140089308A (ko) 2014-07-14
US20140162275A1 (en) 2014-06-12
AU2012220546A1 (en) 2013-09-12
US20120214171A1 (en) 2012-08-23
JP2014506485A (ja) 2014-03-17

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