KR101922409B1 - 화합물들 및 그 용도 - Google Patents

화합물들 및 그 용도 Download PDF

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Publication number
KR101922409B1
KR101922409B1 KR1020127028107A KR20127028107A KR101922409B1 KR 101922409 B1 KR101922409 B1 KR 101922409B1 KR 1020127028107 A KR1020127028107 A KR 1020127028107A KR 20127028107 A KR20127028107 A KR 20127028107A KR 101922409 B1 KR101922409 B1 KR 101922409B1
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KR
South Korea
Prior art keywords
peptides
peptide
species
spp
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Expired - Fee Related
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KR1020127028107A
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English (en)
Korean (ko)
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KR20130043625A (ko
Inventor
데보라 오닐
데리 머서
세드릭 셰리에르
Original Assignee
노바바이오틱스 리미티드
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Priority claimed from PCT/GB2010/000631 external-priority patent/WO2010112848A2/en
Application filed by 노바바이오틱스 리미티드 filed Critical 노바바이오틱스 리미티드
Publication of KR20130043625A publication Critical patent/KR20130043625A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Mobile Radio Communication Systems (AREA)
KR1020127028107A 2010-03-31 2011-03-30 화합물들 및 그 용도 Expired - Fee Related KR101922409B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
WOPCT/GB2010/000631 2010-03-31
PCT/GB2010/000631 WO2010112848A2 (en) 2009-03-31 2010-03-31 Inhibition of biofilm organisms
US39008110P 2010-10-05 2010-10-05
GBGB1016733.6A GB201016733D0 (en) 2010-10-05 2010-10-05 Compounds and their use
GB1016733.6 2010-10-05
US61/390,081 2010-10-05
PCT/GB2011/000480 WO2011121289A2 (en) 2010-03-31 2011-03-30 Compounds and their use

Publications (2)

Publication Number Publication Date
KR20130043625A KR20130043625A (ko) 2013-04-30
KR101922409B1 true KR101922409B1 (ko) 2018-11-27

Family

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KR1020127028107A Expired - Fee Related KR101922409B1 (ko) 2010-03-31 2011-03-30 화합물들 및 그 용도

Country Status (29)

Country Link
US (1) US8901071B2 (enExample)
EP (3) EP2552434B9 (enExample)
JP (1) JP5969457B2 (enExample)
KR (1) KR101922409B1 (enExample)
CN (1) CN102906105B (enExample)
AU (3) AU2011234252B2 (enExample)
BR (1) BR112012024676B1 (enExample)
CA (1) CA2797437C (enExample)
CY (1) CY1121658T1 (enExample)
DK (1) DK2552434T3 (enExample)
ES (1) ES2729313T3 (enExample)
GB (1) GB201016733D0 (enExample)
HR (1) HRP20190982T1 (enExample)
HU (1) HUE044549T2 (enExample)
IL (1) IL222027A (enExample)
LT (1) LT2552434T (enExample)
MX (1) MX2012011369A (enExample)
NZ (2) NZ603200A (enExample)
PL (1) PL2552434T3 (enExample)
PT (1) PT2552434T (enExample)
RS (1) RS58980B1 (enExample)
RU (1) RU2590706C2 (enExample)
SG (1) SG184138A1 (enExample)
SI (1) SI2552434T1 (enExample)
SM (1) SMT201900365T1 (enExample)
TR (1) TR201908150T4 (enExample)
UA (1) UA118167C2 (enExample)
WO (1) WO2011121289A2 (enExample)
ZA (1) ZA201208173B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6495821B2 (ja) * 2012-09-07 2019-04-03 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ ペプチドおよびそれらの使用
WO2015065983A1 (en) * 2013-10-29 2015-05-07 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of gastrointestinal infections
GB2522412A (en) * 2014-01-22 2015-07-29 Agency Science Tech & Res Antimicrobial peptidomimetics
DE102014101663A1 (de) * 2014-02-11 2015-08-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Synthetische artifizielle Peptide mit antimikrobieller Wirkung
GB2524777A (en) * 2014-04-02 2015-10-07 Microarray Ltd Dressing comprising electrodes
WO2016054091A1 (en) * 2014-09-29 2016-04-07 The Research Foundation For The State University Of New York Compositions and methods for reducing cutaneous microbiome malodor
KR101781679B1 (ko) * 2014-11-21 2017-09-26 한양대학교 산학협력단 수 처리 물질 및 그 제조 방법
US11103547B2 (en) 2016-02-04 2021-08-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods for disrupting biofilms
EP3538125A4 (en) 2016-11-09 2020-10-07 Ohio State Innovation Foundation DISULPHIDE-BOUND CELL PENETRATION PEPTIDES, THEIR PREPARATION AND USE METHODS
US11352394B2 (en) 2016-11-22 2022-06-07 Ohio State Innovation Foundation Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof
CN110582507A (zh) * 2017-03-03 2019-12-17 肽逻辑公司 工程化抗微生物两亲性肽及使用方法
US10744313B2 (en) * 2017-07-27 2020-08-18 University Of Utah Research Foundation Therapeutic delivery device
WO2019070962A1 (en) 2017-10-04 2019-04-11 Ohio State Innovation Foundation BICYCLIC PEPTIDE INHIBITORS
WO2019090015A1 (en) * 2017-11-03 2019-05-09 Yale University Peptidic materials that traffic efficiently to the cell cytosol and nucleus
US11793884B2 (en) 2018-01-29 2023-10-24 Ohio State Innovation Foundation Cyclic peptidyl inhibitors of CAL-PDZ binding domain
US11987647B2 (en) 2018-05-09 2024-05-21 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
CN110227144A (zh) * 2019-06-12 2019-09-13 华懿思科(成都)生物科技有限公司 一种消除妇科炎症致病菌及hpv病毒的抗菌肽靶向制剂及其制备方法
WO2021156877A1 (en) * 2020-02-09 2021-08-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Antimicrobial matrix and uses thereof for eliminating microorganisms
CN111533781B (zh) * 2020-03-30 2022-02-08 东北农业大学 非特异受体结合型真菌靶向抗菌肽及其制备方法和应用
US20230287061A1 (en) * 2020-08-10 2023-09-14 Università Cattolica del Sacro Cuore New antimicrobial peptides
CN112586785B (zh) * 2020-12-03 2022-02-08 青岛大学附属医院 一种驴鞭食用胶原蛋白肽-明胶复合胶囊壁材制备方法
RU2771493C1 (ru) * 2021-04-15 2022-05-05 Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") Пептид, обладающий антибактериальной активностью в отношении микроорганизмов с множественной лекарственной устойчивостью
CA3221235A1 (en) * 2021-06-11 2022-12-15 Ali Ladram Short antimicrobial peptides
CN116606347B (zh) * 2023-04-28 2024-03-29 东北农业大学 一种抗菌肽frrffp及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008093058A2 (en) * 2007-02-02 2008-08-07 Novabiotics Limited Peptides and their use

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3561444A (en) 1968-05-22 1971-02-09 Bio Logics Inc Ultrasonic drug nebulizer
US3703173A (en) 1970-12-31 1972-11-21 Ted A Dixon Nebulizer and tent assembly
US4051842A (en) 1975-09-15 1977-10-04 International Medical Corporation Electrode and interfacing pad for electrical physiological systems
DE2626348C3 (de) 1976-06-11 1980-01-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4624251A (en) 1984-09-13 1986-11-25 Riker Laboratories, Inc. Apparatus for administering a nebulized substance
US4635627A (en) 1984-09-13 1987-01-13 Riker Laboratories, Inc. Apparatus and method
US4962091A (en) 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
CA2145093C (en) 1992-09-25 2007-04-10 Lawrence Leroy Kunz Therapeutic inhibitor of vascular smooth muscle cells
GB2408263A (en) 2003-11-14 2005-05-25 Pacgen Biopharmaceuticals Inc Antimicrobial peptides with reduced hemolysis and methods of their use.
DK1778720T3 (da) 2004-08-18 2010-11-29 Novabiotics Ltd Antimikrobielle peptider omfattende et arginin- og/eller lysinholdigt motiv
RU2393224C2 (ru) * 2004-11-12 2010-06-27 Новозимс Эдениум Байотек А/С Полипептиды с противомикробной активностью и кодирующие их полинуклеотиды
WO2007050565A2 (en) * 2005-10-25 2007-05-03 Baylor College Of Medicine Incorporation of antimicrobial combinations onto devices to reduce infection
CN100467481C (zh) * 2006-04-18 2009-03-11 河北师范大学 棕点湍蛙抗菌多肽及其在制药中的应用
CN101070341A (zh) * 2006-05-08 2007-11-14 徐永强 无致突变作用的抗菌多肽
CA2660668C (en) * 2006-08-21 2016-06-28 The University Of British Columbia Small cationic antimicrobial peptides
CN101168564B (zh) * 2007-10-22 2012-03-21 中国科学院昆明动物研究所 人源性抗菌肽及其衍生物的用途
EP2168590A1 (en) 2008-09-24 2010-03-31 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Antimicrobial peptides
GB0905451D0 (en) * 2009-03-31 2009-05-13 Novabiotics Ltd Biofilms

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008093058A2 (en) * 2007-02-02 2008-08-07 Novabiotics Limited Peptides and their use

Also Published As

Publication number Publication date
JP5969457B2 (ja) 2016-08-17
ZA201208173B (en) 2013-07-31
AU2016208308B2 (en) 2018-01-18
NZ603200A (en) 2014-02-28
PL2552434T3 (pl) 2019-09-30
SI2552434T1 (sl) 2019-08-30
AU2016208308A1 (en) 2016-08-11
CN102906105B (zh) 2017-05-10
EP3479824A2 (en) 2019-05-08
AU2011234252B2 (en) 2016-05-12
RS58980B1 (sr) 2019-08-30
DK2552434T3 (da) 2019-06-11
HUE044549T2 (hu) 2019-11-28
AU2018202201B2 (en) 2019-12-05
MX2012011369A (es) 2012-11-30
ES2729313T3 (es) 2019-10-31
EP2552434B9 (en) 2019-09-11
RU2590706C2 (ru) 2016-07-10
CY1121658T1 (el) 2020-07-31
KR20130043625A (ko) 2013-04-30
CA2797437A1 (en) 2011-10-06
US20130102524A1 (en) 2013-04-25
RU2012145756A (ru) 2014-05-10
GB201016733D0 (en) 2010-11-17
HRP20190982T1 (hr) 2019-10-18
EP3479824A3 (en) 2019-08-14
IL222027A (en) 2016-11-30
EP3578193C0 (en) 2023-09-06
EP3578193A3 (en) 2020-05-20
SMT201900365T1 (it) 2019-07-11
LT2552434T (lt) 2019-07-25
EP3578193B1 (en) 2023-09-06
BR112012024676B1 (pt) 2022-05-03
AU2011234252A1 (en) 2012-11-22
CA2797437C (en) 2017-11-07
US8901071B2 (en) 2014-12-02
CN102906105A (zh) 2013-01-30
BR112012024676A2 (pt) 2016-06-07
SG184138A1 (en) 2012-10-30
AU2018202201A1 (en) 2018-04-26
JP2013523703A (ja) 2013-06-17
UA118167C2 (uk) 2018-12-10
WO2011121289A2 (en) 2011-10-06
TR201908150T4 (tr) 2019-06-21
EP3578193A2 (en) 2019-12-11
NZ618571A (en) 2015-02-27
WO2011121289A3 (en) 2012-03-15
EP2552434A2 (en) 2013-02-06
EP2552434B1 (en) 2019-05-08
PT2552434T (pt) 2019-06-12

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