KR101903193B1 - 녹내장 진단 방법 - Google Patents

녹내장 진단 방법 Download PDF

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KR101903193B1
KR101903193B1 KR1020127029751A KR20127029751A KR101903193B1 KR 101903193 B1 KR101903193 B1 KR 101903193B1 KR 1020127029751 A KR1020127029751 A KR 1020127029751A KR 20127029751 A KR20127029751 A KR 20127029751A KR 101903193 B1 KR101903193 B1 KR 101903193B1
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glaucoma
antigen
ocular
antigens
alpha
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KR20130122706A (ko
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프란즈 그루스
닐스 뵘
노베르트 파이퍼
카타리나 벨
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엠-랩 게엠베하
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/16Ophthalmology
    • G01N2800/168Glaucoma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rehabilitation Therapy (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127029751A 2010-04-13 2011-04-13 녹내장 진단 방법 Active KR101903193B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34236310P 2010-04-13 2010-04-13
US61/342,363 2010-04-13
PCT/CH2011/000077 WO2011127616A1 (en) 2010-04-13 2011-04-13 Diagnostic methods for glaucoma

Publications (2)

Publication Number Publication Date
KR20130122706A KR20130122706A (ko) 2013-11-08
KR101903193B1 true KR101903193B1 (ko) 2018-10-01

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US (1) US10175251B2 (enExample)
EP (1) EP2558862B1 (enExample)
JP (2) JP2013529292A (enExample)
KR (1) KR101903193B1 (enExample)
CN (1) CN103003693B (enExample)
AU (1) AU2011241402B2 (enExample)
BR (1) BR112012026219B1 (enExample)
CA (1) CA2795270C (enExample)
DK (1) DK2558862T3 (enExample)
ES (1) ES2712060T3 (enExample)
HR (1) HRP20190278T1 (enExample)
HU (1) HUE042703T2 (enExample)
PL (1) PL2558862T3 (enExample)
RU (1) RU2657515C2 (enExample)
TR (1) TR201902542T4 (enExample)
WO (1) WO2011127616A1 (enExample)
ZA (1) ZA201207935B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220027305A (ko) 2020-08-25 2022-03-08 사회복지법인 삼성생명공익재단 안질환 시야 손상 예후 예측 시스템 및 방법과 이를 위한 컴퓨터 프로그램

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140147413A1 (en) * 2011-02-28 2014-05-29 Dong Feng Chen Therapies That Target Autoimmunity For Treating Glaucoma And Optic Neuropathy
US10842849B2 (en) 2011-02-28 2020-11-24 The Schepens Eye Research Institute, Inc. Methods for promoting neuronal outgrowth by insulin-like growth factor binding protein-like 1 (IGFBPL-1) in glaucoma or leber's optic neuropathy
US20150019136A1 (en) * 2012-02-21 2015-01-15 The Regents Of The University Of California Systems and methods for determining retinal ganglion cell populations and associated treatments
ES2759026T3 (es) * 2013-02-26 2020-05-07 Inst Oftalmologico Fernandez Vega S L Método para el diagnóstico de glaucoma basándose en la determinación de niveles de proteínas séricas
US20170239331A1 (en) * 2014-10-15 2017-08-24 Rapid Pathogen Screening, Inc. Formulations for histatin protectives and therapeutics
JP6499918B2 (ja) 2015-05-20 2019-04-10 株式会社トプコン 眼科検査支援システム及び眼科検査支援サーバ
RU2617066C1 (ru) * 2016-04-01 2017-04-19 Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ определения показаний к интравитреальному введению цилиарного нейротрофического фактора при лечении заболеваний зрительно-нервного аппарата глаза
WO2018106594A2 (en) 2016-12-05 2018-06-14 The Jackson Laboratory Fat droplets in retina and optic nerve as a diagnostic marker for neurodegeneration and glaucoma in humans
JP7202609B2 (ja) * 2017-12-13 2023-01-12 国立大学法人東北大学 視神経障害の診断用バイオマーカー
CN108229545B (zh) * 2017-12-22 2021-09-14 北京市商汤科技开发有限公司 青光眼诊断的方法、装置及电子设备
CA3132333A1 (en) * 2019-03-04 2020-09-10 The Schepens Eye Research Institute, Inc. Modulating neuroinflammation
CN111856037B (zh) * 2020-07-31 2021-06-22 四川大学华西第二医院 Unc45a与hsp10的比值在pop早期预警、诊断、预后评估中的应用和产品
CN113444789A (zh) * 2021-08-27 2021-09-28 中国医学科学院北京协和医院 青光眼相关生物标志物及其应用
CN114965664A (zh) * 2022-03-21 2022-08-30 上海交通大学 一种获取泪液代谢指纹谱图的方法及筛选方法
CN118425510B (zh) * 2024-05-17 2024-11-19 上海市第一人民医院 一种青光眼诊断的生物标志物及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004007749A2 (en) * 2002-07-12 2004-01-22 University Of Washington Methods and systems for extended in vitro culture of neuronal cells
WO2004036220A1 (en) * 2002-10-18 2004-04-29 Rescom Gmbh Diagnosis of glaucoma by complex autoantibody repertoires in body fluids
WO2009145478A2 (ko) * 2008-04-02 2009-12-03 (주)루미아이제네틱스 녹내장 진단용 키트
JP2010507069A (ja) * 2006-07-08 2010-03-04 ユニバーシティー オブ ケンタッキー リサーチ ファンデーション 肺癌診断アッセイ

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9419267D0 (en) 1994-09-23 1994-11-09 Unilever Plc Assay devices
RU2187983C2 (ru) 1998-11-10 2002-08-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ диагностики характера течения глаукомы
US20020102581A1 (en) * 1999-02-19 2002-08-01 Hageman Gregory S. Diagnostics and therapeutics for ocular disorders
US20030149997A1 (en) 1999-02-19 2003-08-07 Hageman Gregory S. Diagnostics and therapeutics for arterial wall disruptive disorders
US7011952B2 (en) * 2000-02-22 2006-03-14 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
DK2026073T3 (en) 2000-04-29 2016-07-25 Univ Iowa Res Found Diagnosis and treatment of macular degeneration-related disorders
CN1393470A (zh) * 2001-06-29 2003-01-29 上海博德基因开发有限公司 一种多肽——beta转导素-45.65和编码这种多肽的多核苷酸
ATE526041T1 (de) * 2001-12-11 2011-10-15 Fibrogen Inc Verfahren zur hemmung okularer vorgänge
US7662389B2 (en) * 2003-12-17 2010-02-16 Alcon, Inc. Use of serum amyloid A gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
US7442720B2 (en) * 2003-12-19 2008-10-28 Omega Bio-Pharma (I.P.3) Limited Compositions and methods for treating diabetes
AU2006272497B2 (en) * 2005-07-27 2012-07-19 University Of Florida Research Foundation, Inc. Small compounds that correct protein misfolding and uses thereof
EP1832600A1 (en) * 2006-03-09 2007-09-12 Max-Delbrück-Centrum Für Molekulare Medizin Peptides against autoantibodies associated with glaucoma and use of these peptides
RU2314535C1 (ru) 2006-07-05 2008-01-10 Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по здравоохранению и социальному развитию" Способ диагностики начальной стадии открытоугольной глаукомы
EP1929937A1 (de) * 2006-12-07 2008-06-11 F. Hoffmann-Roche AG Vorrichtung und Verfahren zum Untersuchen von Körperflüssigkeiten
RU2371721C2 (ru) 2007-06-25 2009-10-27 Закрытое акционерное общество "Молекулярно-медицинские технологии" Устройство для диагностики с использованием биочипов
GB0724412D0 (en) * 2007-12-14 2008-02-06 Ucl Business Plc Marker
EP2354792A1 (en) 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
KR20100087276A (ko) 2010-07-21 2010-08-04 (주)루미아이제네틱스 녹내장 진단용 키트
KR20100087275A (ko) 2010-07-21 2010-08-04 (주)루미아이제네틱스 녹내장 진단용 키트

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004007749A2 (en) * 2002-07-12 2004-01-22 University Of Washington Methods and systems for extended in vitro culture of neuronal cells
WO2004036220A1 (en) * 2002-10-18 2004-04-29 Rescom Gmbh Diagnosis of glaucoma by complex autoantibody repertoires in body fluids
JP2010507069A (ja) * 2006-07-08 2010-03-04 ユニバーシティー オブ ケンタッキー リサーチ ファンデーション 肺癌診断アッセイ
WO2009145478A2 (ko) * 2008-04-02 2009-12-03 (주)루미아이제네틱스 녹내장 진단용 키트

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220027305A (ko) 2020-08-25 2022-03-08 사회복지법인 삼성생명공익재단 안질환 시야 손상 예후 예측 시스템 및 방법과 이를 위한 컴퓨터 프로그램

Also Published As

Publication number Publication date
BR112012026219B1 (pt) 2019-12-10
DK2558862T3 (en) 2019-03-18
PL2558862T3 (pl) 2019-07-31
HRP20190278T1 (hr) 2019-04-19
AU2011241402A1 (en) 2012-11-15
BR112012026219A2 (pt) 2016-07-12
AU2011241402B2 (en) 2016-09-15
WO2011127616A1 (en) 2011-10-20
US20130172204A1 (en) 2013-07-04
CN103003693B (zh) 2016-07-06
EP2558862B1 (en) 2018-11-21
ES2712060T3 (es) 2019-05-09
ZA201207935B (en) 2019-07-31
EP2558862A1 (en) 2013-02-20
TR201902542T4 (tr) 2019-03-21
RU2012147551A (ru) 2014-05-20
JP2016048265A (ja) 2016-04-07
KR20130122706A (ko) 2013-11-08
CA2795270C (en) 2021-06-08
US10175251B2 (en) 2019-01-08
CA2795270A1 (en) 2011-10-20
RU2657515C2 (ru) 2018-06-14
CN103003693A (zh) 2013-03-27
HUE042703T2 (hu) 2019-07-29
JP6225157B2 (ja) 2017-11-01
JP2013529292A (ja) 2013-07-18

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