JP2013529292A - 緑内障の診断方法 - Google Patents

緑内障の診断方法 Download PDF

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Publication number
JP2013529292A
JP2013529292A JP2013504084A JP2013504084A JP2013529292A JP 2013529292 A JP2013529292 A JP 2013529292A JP 2013504084 A JP2013504084 A JP 2013504084A JP 2013504084 A JP2013504084 A JP 2013504084A JP 2013529292 A JP2013529292 A JP 2013529292A
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Prior art keywords
antigen
glaucoma
antigens
protein
sample
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JP2013504084A
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Japanese (ja)
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JP2013529292A5 (enExample
Inventor
グルース,フランツ
ベーム,ニルス
プファイファー,ノルベルト
ベル,カタリーナ
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M Lab AG
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M Lab AG
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Publication of JP2013529292A5 publication Critical patent/JP2013529292A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/16Ophthalmology
    • G01N2800/168Glaucoma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rehabilitation Therapy (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013504084A 2010-04-13 2011-04-13 緑内障の診断方法 Pending JP2013529292A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34236310P 2010-04-13 2010-04-13
US61/342,363 2010-04-13
PCT/CH2011/000077 WO2011127616A1 (en) 2010-04-13 2011-04-13 Diagnostic methods for glaucoma

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015253808A Division JP6225157B2 (ja) 2010-04-13 2015-12-25 緑内障の診断方法

Publications (2)

Publication Number Publication Date
JP2013529292A true JP2013529292A (ja) 2013-07-18
JP2013529292A5 JP2013529292A5 (enExample) 2014-05-29

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JP2013504084A Pending JP2013529292A (ja) 2010-04-13 2011-04-13 緑内障の診断方法
JP2015253808A Active JP6225157B2 (ja) 2010-04-13 2015-12-25 緑内障の診断方法

Family Applications After (1)

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Country Status (17)

Country Link
US (1) US10175251B2 (enExample)
EP (1) EP2558862B1 (enExample)
JP (2) JP2013529292A (enExample)
KR (1) KR101903193B1 (enExample)
CN (1) CN103003693B (enExample)
AU (1) AU2011241402B2 (enExample)
BR (1) BR112012026219B1 (enExample)
CA (1) CA2795270C (enExample)
DK (1) DK2558862T3 (enExample)
ES (1) ES2712060T3 (enExample)
HR (1) HRP20190278T1 (enExample)
HU (1) HUE042703T2 (enExample)
PL (1) PL2558862T3 (enExample)
RU (1) RU2657515C2 (enExample)
TR (1) TR201902542T4 (enExample)
WO (1) WO2011127616A1 (enExample)
ZA (1) ZA201207935B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10548472B2 (en) 2015-05-20 2020-02-04 Kabushiki Kaisha Topcon Ophthalmic examination support system, ophthalmic examination support server and ophthalmic examination support device
JP2022524325A (ja) * 2019-03-04 2022-05-02 ザ スケペンス アイ リサーチ インスティテュート,インコーポレイテッド 神経炎症の調節
US12295985B2 (en) 2011-02-28 2025-05-13 The Schepens Eye Research Institute, Inc. Methods of reducing severity of glaucoma by intravitreal administration of insulin-like growth factor binding protein-like 1 (IGFBPL1)

Families Citing this family (13)

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US20140147413A1 (en) * 2011-02-28 2014-05-29 Dong Feng Chen Therapies That Target Autoimmunity For Treating Glaucoma And Optic Neuropathy
US20150019136A1 (en) * 2012-02-21 2015-01-15 The Regents Of The University Of California Systems and methods for determining retinal ganglion cell populations and associated treatments
ES2759026T3 (es) * 2013-02-26 2020-05-07 Inst Oftalmologico Fernandez Vega S L Método para el diagnóstico de glaucoma basándose en la determinación de niveles de proteínas séricas
US20170239331A1 (en) * 2014-10-15 2017-08-24 Rapid Pathogen Screening, Inc. Formulations for histatin protectives and therapeutics
RU2617066C1 (ru) * 2016-04-01 2017-04-19 Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ определения показаний к интравитреальному введению цилиарного нейротрофического фактора при лечении заболеваний зрительно-нервного аппарата глаза
WO2018106594A2 (en) 2016-12-05 2018-06-14 The Jackson Laboratory Fat droplets in retina and optic nerve as a diagnostic marker for neurodegeneration and glaucoma in humans
JP7202609B2 (ja) * 2017-12-13 2023-01-12 国立大学法人東北大学 視神経障害の診断用バイオマーカー
CN108229545B (zh) * 2017-12-22 2021-09-14 北京市商汤科技开发有限公司 青光眼诊断的方法、装置及电子设备
CN111856037B (zh) * 2020-07-31 2021-06-22 四川大学华西第二医院 Unc45a与hsp10的比值在pop早期预警、诊断、预后评估中的应用和产品
KR102596340B1 (ko) 2020-08-25 2023-11-02 사회복지법인 삼성생명공익재단 안질환 시야 손상 예후 예측 시스템 및 방법과 이를 위한 컴퓨터 프로그램
CN113444789A (zh) * 2021-08-27 2021-09-28 中国医学科学院北京协和医院 青光眼相关生物标志物及其应用
CN114965664A (zh) * 2022-03-21 2022-08-30 上海交通大学 一种获取泪液代谢指纹谱图的方法及筛选方法
CN118425510B (zh) * 2024-05-17 2024-11-19 上海市第一人民医院 一种青光眼诊断的生物标志物及其应用

Citations (5)

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WO2004036220A1 (en) * 2002-10-18 2004-04-29 Rescom Gmbh Diagnosis of glaucoma by complex autoantibody repertoires in body fluids
JP2007514771A (ja) * 2003-12-19 2007-06-07 オメガ バイオ‐ファーマ(アイ.ピー.3)リミテッド 糖尿病を治療するための組成物および方法
WO2009077750A1 (en) * 2007-12-14 2009-06-25 Ucl Business Plc Fluorescent marker for cell death in the eye
WO2009145478A2 (ko) * 2008-04-02 2009-12-03 (주)루미아이제네틱스 녹내장 진단용 키트
JP2010507069A (ja) * 2006-07-08 2010-03-04 ユニバーシティー オブ ケンタッキー リサーチ ファンデーション 肺癌診断アッセイ

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US20020102581A1 (en) * 1999-02-19 2002-08-01 Hageman Gregory S. Diagnostics and therapeutics for ocular disorders
US20030149997A1 (en) 1999-02-19 2003-08-07 Hageman Gregory S. Diagnostics and therapeutics for arterial wall disruptive disorders
US7011952B2 (en) * 2000-02-22 2006-03-14 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
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CN1393470A (zh) * 2001-06-29 2003-01-29 上海博德基因开发有限公司 一种多肽——beta转导素-45.65和编码这种多肽的多核苷酸
ATE526041T1 (de) * 2001-12-11 2011-10-15 Fibrogen Inc Verfahren zur hemmung okularer vorgänge
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RU2314535C1 (ru) 2006-07-05 2008-01-10 Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по здравоохранению и социальному развитию" Способ диагностики начальной стадии открытоугольной глаукомы
EP1929937A1 (de) * 2006-12-07 2008-06-11 F. Hoffmann-Roche AG Vorrichtung und Verfahren zum Untersuchen von Körperflüssigkeiten
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EP2354792A1 (en) 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
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KR20100087275A (ko) 2010-07-21 2010-08-04 (주)루미아이제네틱스 녹내장 진단용 키트

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004036220A1 (en) * 2002-10-18 2004-04-29 Rescom Gmbh Diagnosis of glaucoma by complex autoantibody repertoires in body fluids
JP2007514771A (ja) * 2003-12-19 2007-06-07 オメガ バイオ‐ファーマ(アイ.ピー.3)リミテッド 糖尿病を治療するための組成物および方法
JP2010507069A (ja) * 2006-07-08 2010-03-04 ユニバーシティー オブ ケンタッキー リサーチ ファンデーション 肺癌診断アッセイ
WO2009077750A1 (en) * 2007-12-14 2009-06-25 Ucl Business Plc Fluorescent marker for cell death in the eye
WO2009145478A2 (ko) * 2008-04-02 2009-12-03 (주)루미아이제네틱스 녹내장 진단용 키트

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12295985B2 (en) 2011-02-28 2025-05-13 The Schepens Eye Research Institute, Inc. Methods of reducing severity of glaucoma by intravitreal administration of insulin-like growth factor binding protein-like 1 (IGFBPL1)
US10548472B2 (en) 2015-05-20 2020-02-04 Kabushiki Kaisha Topcon Ophthalmic examination support system, ophthalmic examination support server and ophthalmic examination support device
JP2022524325A (ja) * 2019-03-04 2022-05-02 ザ スケペンス アイ リサーチ インスティテュート,インコーポレイテッド 神経炎症の調節
JP7738377B2 (ja) 2019-03-04 2025-09-12 マサチューセッツ アイ アンド イヤー インファーマリー 神経炎症の調節

Also Published As

Publication number Publication date
BR112012026219B1 (pt) 2019-12-10
DK2558862T3 (en) 2019-03-18
PL2558862T3 (pl) 2019-07-31
HRP20190278T1 (hr) 2019-04-19
AU2011241402A1 (en) 2012-11-15
BR112012026219A2 (pt) 2016-07-12
AU2011241402B2 (en) 2016-09-15
WO2011127616A1 (en) 2011-10-20
US20130172204A1 (en) 2013-07-04
CN103003693B (zh) 2016-07-06
EP2558862B1 (en) 2018-11-21
ES2712060T3 (es) 2019-05-09
ZA201207935B (en) 2019-07-31
EP2558862A1 (en) 2013-02-20
TR201902542T4 (tr) 2019-03-21
RU2012147551A (ru) 2014-05-20
KR101903193B1 (ko) 2018-10-01
JP2016048265A (ja) 2016-04-07
KR20130122706A (ko) 2013-11-08
CA2795270C (en) 2021-06-08
US10175251B2 (en) 2019-01-08
CA2795270A1 (en) 2011-10-20
RU2657515C2 (ru) 2018-06-14
CN103003693A (zh) 2013-03-27
HUE042703T2 (hu) 2019-07-29
JP6225157B2 (ja) 2017-11-01

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