KR101901465B1 - 위장관의 기능적 질환 또는 상태를 치료하는 제약학적 복합 조성물 및 방법들 - Google Patents

위장관의 기능적 질환 또는 상태를 치료하는 제약학적 복합 조성물 및 방법들 Download PDF

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KR101901465B1
KR101901465B1 KR1020137003751A KR20137003751A KR101901465B1 KR 101901465 B1 KR101901465 B1 KR 101901465B1 KR 1020137003751 A KR1020137003751 A KR 1020137003751A KR 20137003751 A KR20137003751 A KR 20137003751A KR 101901465 B1 KR101901465 B1 KR 101901465B1
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antibody
activated
pharmaceutical composition
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KR20130060264A (ko
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올레그 일리치 엡쉬테인
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올레그 일리치 엡쉬테인
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Priority claimed from RU2010129293/15A external-priority patent/RU2500427C2/ru
Priority claimed from RU2011124809/15A external-priority patent/RU2532323C2/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
KR1020137003751A 2010-07-15 2011-07-15 위장관의 기능적 질환 또는 상태를 치료하는 제약학적 복합 조성물 및 방법들 Expired - Fee Related KR101901465B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
RU2010129293 2010-07-15
RU2010129293/15A RU2500427C2 (ru) 2010-07-15 2010-07-15 Лекарственное средство для лечения функциональных нарушений желудочно-кишечного тракта и способ лечения функциональных нарушений желудочно-кишечного тракта
RU2011124809 2011-06-20
RU2011124809/15A RU2532323C2 (ru) 2011-06-20 2011-06-20 Лекарственное средство для лечения патологического синдрома и способ лечения функциональных нарушений кишечника
PCT/IB2011/002178 WO2012007839A2 (en) 2010-07-15 2011-07-15 Combination pharmaceutical composition and methods of treating functional diseases or conditions of gastrointestinal tract

Publications (2)

Publication Number Publication Date
KR20130060264A KR20130060264A (ko) 2013-06-07
KR101901465B1 true KR101901465B1 (ko) 2018-09-21

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ID=44863147

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KR1020137003751A Expired - Fee Related KR101901465B1 (ko) 2010-07-15 2011-07-15 위장관의 기능적 질환 또는 상태를 치료하는 제약학적 복합 조성물 및 방법들

Country Status (24)

Country Link
US (1) US8637030B2 (enExample)
EP (1) EP2593138A2 (enExample)
JP (2) JP2013532181A (enExample)
KR (1) KR101901465B1 (enExample)
CN (1) CN103096927A (enExample)
AR (1) AR082245A1 (enExample)
AU (1) AU2011278032B2 (enExample)
BR (1) BR112013000842A2 (enExample)
CA (1) CA2804964C (enExample)
CL (1) CL2013000097A1 (enExample)
DE (1) DE112011102355T5 (enExample)
EA (1) EA030542B1 (enExample)
ES (1) ES2425004R1 (enExample)
FR (1) FR2962651A1 (enExample)
GB (1) GB2496794B (enExample)
IL (1) IL224215A (enExample)
IT (1) ITTO20110628A1 (enExample)
MX (1) MX2013000542A (enExample)
MY (1) MY157564A (enExample)
NZ (1) NZ606765A (enExample)
PE (1) PE20130397A1 (enExample)
PH (1) PH12013500108A1 (enExample)
SG (1) SG187035A1 (enExample)
WO (1) WO2012007839A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2181297C2 (ru) 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
UA76638C2 (en) 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
RU2309732C1 (ru) * 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
EA029400B1 (ru) 2010-07-15 2018-03-30 Олег Ильич ЭПШТЕЙН Фармацевтическая композиция для лечения ожирения и сопутствующих метаболических расстройств и способ лечения
MX2013000543A (es) 2010-07-15 2013-10-28 Oleg Iliich Epshtein Un metodo para aumentar el efecto de una forma activa potenciada de un anticuerpo.
FR2962652A1 (fr) 2010-07-15 2012-01-20 Oleg Iliich Epshtein Composition pharmaceutique d'association et son utilisation dans des procedes pour traiter les maladies ou affections associees a des maladies neurodegeneratives
FR2962655A1 (fr) * 2010-07-15 2012-01-20 Oleg Iliich Epshtein Composition pharmaceutique d'association et ses utilisations dans les procedes de traitement des troubles du systeme genito-urinaire
PH12013500144A1 (en) 2010-07-21 2018-03-21 Oleg Iliich Epshtein A method of treating attention deficit hyperactivity disorder
FR2962909A1 (fr) 2010-07-21 2012-01-27 Oleg Iliich Epshtein Composition pharmaceutique d'association et son utilisation dans des procedes pour traiter les maladies ou affections associees avec une maladie ou affection respiratoire
AR083495A1 (es) 2010-10-22 2013-02-27 Esbatech Alcon Biomed Res Unit Anticuerpos estables y solubles
RU2013111962A (ru) 2013-03-18 2014-09-27 Олег Ильич Эпштейн Способ определения выраженности модифицирующей активности, ассоциированной с носителем
RU2013111961A (ru) 2013-03-18 2014-09-27 Олег Ильич Эпштейн Способ определения выраженности модифицирующей активности, ассоциированной с носителем
CN106349388B (zh) * 2015-07-17 2021-04-02 上海佳文英莉生物技术有限公司 一种促细胞程序性坏死抗体及其应用
CN207908510U (zh) 2016-09-21 2018-09-25 维布兰特公司 安装在抽水马桶上的传感器
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
CN114375200A (zh) * 2019-08-29 2022-04-19 奥列格·伊利奇·爱泼斯坦 治疗传染病的药物和方法
JPWO2024111633A1 (enExample) * 2022-11-24 2024-05-30
WO2025144085A1 (ru) * 2023-12-25 2025-07-03 Леонид Владимирович КОСМОДЕМЬЯНСКИЙ Способ лечения боли

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2197266C1 (ru) 2001-06-01 2003-01-27 Эпштейн Олег Ильич Лекарственное средство и способ лечения эрозивных и воспалительных заболеваний желудочно-кишечного тракта
EA008605B1 (ru) 2002-08-02 2007-06-29 Олег Ильич ЭПШТЕЙН Лекарственное средство для коррекции патологических иммунных реакций

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311897A (en) 1979-08-28 1982-01-19 Union Carbide Corporation Plasma arc torch and nozzle assembly
US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4987127A (en) 1989-01-31 1991-01-22 Dal Sirany Method of treating a virus outbreak
SU1730144A1 (ru) 1989-02-24 1992-04-30 Научный Центр По Разработке И Внедрению Современных Методов Молекулярной Диагностики Способ подавлени репродукции вирусов
GB8905400D0 (en) 1989-03-09 1989-04-19 Jonker Margreet Medicaments
US5698195A (en) 1991-03-18 1997-12-16 New York University Medical Center Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies
RU2007989C1 (ru) 1991-11-12 1994-02-28 Акционерное общество "Трейдис" Способ габович подбора гомеопатических препаратов и их разовой дозы
JP3616091B2 (ja) 1992-10-08 2005-02-02 ザ ケネディー インスティチュート オブ リューマトロジー 自己免疫疾患および炎症性疾患の治療
DK140992D0 (da) 1992-11-24 1992-11-24 Ole Buchardt Fremgangsmaade til frembringelse af antistoffer mod haptener og andre b-celle-antigener, antistoffer opnaaet ved fremgangsmaaden og anvendelse af disse antistoffer til fremstilling af vacciner, isaer til veterinaermedicinsk brug
US5879677A (en) 1992-12-09 1999-03-09 The Scripps Research Institute Method for inhibition of cerebral tissue factor mediated reperfusion damage
WO1994022846A1 (en) 1993-03-30 1994-10-13 Pfizer Inc. Compounds enhancing antitumor activity of other cytotoxic agents
RU2033784C1 (ru) 1993-05-28 1995-04-30 Индивидуальное частное предприятие "Диалог" Устройство для репродуцирования гомеопатических и изопатических препаратов
IT1261849B (it) 1993-09-02 1996-06-03 Avantgarde Spa Dispositivo medico per la somministrazione di principi attivi o farmaci a bassissimo dosaggio, in particolare di farmaci omeopatici.
EP0652014A1 (en) 1993-11-10 1995-05-10 National Institute Of Immunology Treatment of prostatic hypertrophy
NZ278607A (en) 1994-02-07 1999-05-28 Knoll Ag Use of tnf antagonists for treating disorders involving elevated serum levels of il-6 wherein the serum levels are 500pg/ml or above
JP3696884B2 (ja) 1994-03-25 2005-09-21 アイソテクニカ、インコーポレーテッド ジュウテリウム化による薬物の効能の増強
US5629286A (en) 1994-03-31 1997-05-13 Brewitt; Barbara Homeopathic dilutions of growth factors
IL110035A0 (en) 1994-06-16 1994-10-07 Tapuach Natural Technologies 1 Homeopathic formulations
RU2137483C1 (ru) 1995-08-02 1999-09-20 Божедомов Владимир Александрович Способ лечения урогенитальной хламидийной, уреаплазменной и микоплазменной инфекции
AU723812B2 (en) 1996-02-12 2000-09-07 Oleg Iliich Epshtein Medicinal preparation and a method of medicinal action on human organism
EP0894501A4 (en) 1996-04-19 1999-08-04 Chugai Pharmaceutical Co Ltd REMEDY FOR RHUMATOID ARTHRITIS CONTAINING ANTI-IL-8 ANTIBODY AS ACTIVE INGREDIENT
IL118096A0 (en) 1996-05-01 1996-09-12 Yeda Res & Dev Antibodies against interferon alpha/beta receptor
RU2132181C1 (ru) 1996-09-30 1999-06-27 Эпштейн Олег Ильич Средство для воздействия на организм
RU2114605C1 (ru) 1996-09-30 1998-07-10 Олег Ильич Эпштейн Защитная добавка для косметических средств
RU2114646C1 (ru) 1996-09-30 1998-07-10 Олег Ильич Эпштейн Способ повышения защитных свойств организма при воздействии внешних физических факторов
RU2099052C1 (ru) 1996-12-26 1997-12-20 Тамара Михайловна Воробьева Лекарственное средство для восстановления психофизиологического гомеостаза, нарушенного вследствие употребления алкоголя
RU2103999C1 (ru) 1997-01-31 1998-02-10 Олег Ильич Эпштейн Способ лечения алкоголизма
RU2104006C1 (ru) 1997-02-14 1998-02-10 Олег Ильич Эпштейн Способ лечения наркомании
RU2104032C1 (ru) 1997-03-11 1998-02-10 Общество с ограниченной ответственностью "Снежный барс" Способ усиления лечебного эффекта лекарственных средств
DE19746868A1 (de) 1997-10-23 1999-04-29 Knoll Ag Verwendung von TNF-Antagonisten als Arzneimittel zur Behandlung von septischen Erkrankungen
RU2122858C1 (ru) 1997-12-29 1998-12-10 Яковлева Людмила Борисовна Гомеопатическое лекарственное средство седативного действия "вернисон"
RU2187334C2 (ru) 1998-05-22 2002-08-20 Эпштейн Олег Ильич Способ коррекции нарушенного иммунного гомеостаза и лекарственное средство
RU2161955C1 (ru) 1999-07-16 2001-01-20 Эпштейн Олег Ильич Способ изменения физико-химических или физико-химических и биологических свойств вещества
RU2181297C2 (ru) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
RU2177795C1 (ru) 2001-02-15 2002-01-10 Эпштей Олег Ильич Гомеопатическое лекарственное средство для лечения и профилактики аденовирусных инфекций у детей
RU2192882C1 (ru) 2001-04-18 2002-11-20 Эпштейн Олег Ильич Лекарственное средство и способ лечения патологического синдрома, обусловленного нарушением кроветворения
WO2003037372A1 (en) 2001-10-31 2003-05-08 Oleg Iliich Epshtein Method for restoring disordered physiological processes and a medicament for carrying out said method
RU2201255C1 (ru) 2001-12-26 2003-03-27 Эпштейн Олег Ильич Лекарственное средство и способ регуляции сосудистого тонуса
RU2001134982A (ru) 2001-12-26 2004-02-20 Олег Ильич Эпштейн Способ коррекции иммунного ответа и лекарственное средство
RU2205026C1 (ru) 2002-03-15 2003-05-27 Эпштейн Олег Ильич Лекарственное средство и способ лечения патологического синдрома, обусловленного нарушением кроветворения
UA76641C2 (uk) 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Гомеопатичний лікарський засіб та спосіб лікування захворювань передміхурової залози
UA76638C2 (en) 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
GB2414670B (en) 2003-03-14 2008-03-19 Nutrition Res Inc Homeopathic formulations useful for treating pain and/or inflammation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2197266C1 (ru) 2001-06-01 2003-01-27 Эпштейн Олег Ильич Лекарственное средство и способ лечения эрозивных и воспалительных заболеваний желудочно-кишечного тракта
EA008605B1 (ru) 2002-08-02 2007-06-29 Олег Ильич ЭПШТЕЙН Лекарственное средство для коррекции патологических иммунных реакций

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Bulletin of experimental biology and medicine. 2003, 135(7):117-119.

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GB2496794A (en) 2013-05-22
JP2016210787A (ja) 2016-12-15
KR20130060264A (ko) 2013-06-07
PH12013500108A1 (en) 2017-01-06
AR082245A1 (es) 2012-11-21
CA2804964C (en) 2016-06-28
NZ606765A (en) 2015-08-28
CN103096927A (zh) 2013-05-08
WO2012007839A3 (en) 2012-04-26
IL224215A (en) 2016-03-31
EP2593138A2 (en) 2013-05-22
DE112011102355T5 (de) 2013-04-25
ES2425004R1 (es) 2014-07-09
AU2011278032B2 (en) 2015-07-23
GB201302654D0 (en) 2013-04-03
WO2012007839A2 (en) 2012-01-19
EA201300125A1 (ru) 2013-12-30
EA030542B1 (ru) 2018-08-31
US20130004574A1 (en) 2013-01-03
ES2425004A2 (es) 2013-10-10
CL2013000097A1 (es) 2015-01-09
US8637030B2 (en) 2014-01-28
GB2496794B (en) 2017-11-01
SG187035A1 (en) 2013-02-28
CA2804964A1 (en) 2012-01-19
FR2962651A1 (fr) 2012-01-20
MY157564A (en) 2016-06-30
BR112013000842A2 (pt) 2016-06-07
AU2011278032A1 (en) 2013-03-07
PE20130397A1 (es) 2013-04-10
ITTO20110628A1 (it) 2012-01-16
MX2013000542A (es) 2013-06-28
JP2013532181A (ja) 2013-08-15

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