KR101839278B1 - 단백질의 역압 여과 - Google Patents

단백질의 역압 여과 Download PDF

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Publication number
KR101839278B1
KR101839278B1 KR1020177015613A KR20177015613A KR101839278B1 KR 101839278 B1 KR101839278 B1 KR 101839278B1 KR 1020177015613 A KR1020177015613 A KR 1020177015613A KR 20177015613 A KR20177015613 A KR 20177015613A KR 101839278 B1 KR101839278 B1 KR 101839278B1
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South Korea
Prior art keywords
protein
pressure
filtrate
filter
liquid mixture
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Korean (ko)
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KR20170070255A (ko
Inventor
네보이사 니콜리치
미하엘라 프레이
볼프강 그라브마이어
토마스 얀치크
마티아스 프리트
클라우스 체츠코비츠
쿠르트 슈네커
바르바라 리글러
알마 카사포비치
Original Assignee
박스알타 인코퍼레이티드
박스앨타 게엠베하
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40602549&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101839278(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 박스알타 인코퍼레이티드, 박스앨타 게엠베하 filed Critical 박스알타 인코퍼레이티드
Publication of KR20170070255A publication Critical patent/KR20170070255A/ko
Application granted granted Critical
Publication of KR101839278B1 publication Critical patent/KR101839278B1/ko
Assigned to 다케다 야쿠힌 고교 가부시키가이샤 reassignment 다케다 야쿠힌 고교 가부시키가이샤 권리의 전부이전등록 Assignors: 박스알타 인코퍼레이티드, 박스앨타 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020177015613A 2007-12-28 2008-12-22 단백질의 역압 여과 Active KR101839278B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1741807P 2007-12-28 2007-12-28
US61/017,418 2007-12-28
PCT/US2008/088005 WO2009086296A2 (en) 2007-12-28 2008-12-22 Counter-pressure filtration of proteins

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020107015781A Division KR101748878B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187006765A Division KR101915445B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과

Publications (2)

Publication Number Publication Date
KR20170070255A KR20170070255A (ko) 2017-06-21
KR101839278B1 true KR101839278B1 (ko) 2018-03-15

Family

ID=40602549

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020177015613A Active KR101839278B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과
KR1020187006765A Active KR101915445B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과
KR1020107015781A Active KR101748878B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020187006765A Active KR101915445B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과
KR1020107015781A Active KR101748878B1 (ko) 2007-12-28 2008-12-22 단백질의 역압 여과

Country Status (18)

Country Link
US (4) US7959809B2 (https=)
EP (2) EP2392317A1 (https=)
JP (4) JP5027310B2 (https=)
KR (3) KR101839278B1 (https=)
CN (1) CN101909599B (https=)
AR (2) AR070061A1 (https=)
AT (1) ATE525062T1 (https=)
AU (1) AU2008345218B2 (https=)
CA (1) CA2709781C (https=)
DK (1) DK2242479T3 (https=)
ES (1) ES2377038T3 (https=)
HR (1) HRP20110927T1 (https=)
NZ (2) NZ600053A (https=)
PL (1) PL2242479T3 (https=)
PT (1) PT2242479E (https=)
SG (1) SG187411A1 (https=)
SI (1) SI2242479T1 (https=)
WO (1) WO2009086296A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2242479T3 (pl) * 2007-12-28 2012-02-29 Baxalta Inc Filtracja białek z zastosowaniem przeciwciśnienia
TWI469992B (zh) * 2008-08-28 2015-01-21 Baxter Int 濃縮剪切靈敏生物聚合物的方法
US10100594B2 (en) * 2013-06-27 2018-10-16 Ge Oil & Gas Uk Limited Control system and a method for monitoring a filter in an underwater hydrocarbon well
ES2916825T3 (es) * 2014-01-20 2022-07-06 UCB Biopharma SRL Procedimiento para la reconstitución de una forma sólida de una composición farmacéutica

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004269529A (ja) 2003-03-06 2004-09-30 Probitas Pharma Sa フィブリノゲン溶液中のウイルスを除去する方法およびこの方法により得られるフィブリノゲン

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DE2624373C2 (de) * 1976-05-31 1983-02-03 Arnold Dr. 8782 Karlstadt Seufert Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII
US5047154A (en) * 1983-03-10 1991-09-10 C.P.C. Engineering Company Method and apparatus for enhancing the flux rate of cross-flow filtration systems
SE443075B (sv) * 1984-06-01 1986-02-17 Alfa Laval Agri Int Forfarande och anordning for framstellning av mjolkkoncentrat genom membranfiltrering
ATE64956T1 (de) * 1984-06-14 1991-07-15 Ciba Geigy Ag Verfahren zur herstellung von thrombininhibitoren.
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
US4774323A (en) * 1987-06-29 1988-09-27 Rorer Pharmaceutical Corporation Purification of von Willebrand Factor solutions using gel permeation chromatography
DE3730868A1 (de) 1987-09-15 1989-03-23 Henkel Kgaa Verfahren zur abtrennung von biotechnisch hergestellten wertstoffen aus einer fermenterbruehe durch querstrom-mikro- und/oder ultrafiltration
SE9003452L (sv) 1990-10-30 1992-05-01 Teinvall Sjoeberg & Broberg Ab Saett och anordning vid vaetskefiltrering
CH687055A5 (de) * 1993-12-03 1996-09-13 Bucher Guyer Ag Masch Verfahren und Vorrichtung zum Eindicken von Fest/Fluessig-Gemischen mittels Membrantechnologie.
US5525144A (en) * 1995-04-20 1996-06-11 A/G Technology Corporation Tangential flow filtering and separating
AT403764B (de) * 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
DE69610227T2 (de) * 1996-07-10 2001-01-04 American National Red Cross, Washington Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten
US5888401A (en) * 1996-09-16 1999-03-30 Union Camp Corporation Method and apparatus for reducing membrane fouling
AT406867B (de) * 1997-02-27 2000-10-25 Immuno Ag Verfahren zur gewinnung von hochreinem vwf oder faktor viii/vwf-komplex
US5947689A (en) * 1997-05-07 1999-09-07 Scilog, Inc. Automated, quantitative, system for filtration of liquids having a pump controller
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
US6139878A (en) 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
MXPA01002908A (es) * 1998-09-21 2002-04-08 E Purdum Howard Metodos y aparatos para procesar materiales sensibles a la temperatura.
DE19906379B4 (de) * 1999-02-16 2006-05-18 Huss, Manfred Herstellung eines aggregierten Molkenproteinprodukts
US6623781B2 (en) 1999-07-26 2003-09-23 Cornell Research Foundation, Inc. Microfiltration of skim milk for cheese making and whey proteins
US6485762B1 (en) * 1999-07-26 2002-11-26 Cornell Research Foundation, Inc. Microfiltration of skim milk for cheese making and whey proteins
DE10211227A1 (de) * 2002-03-13 2003-10-02 Aventis Behring Gmbh Verfahren zur Rekonstitution von Iyophilisierten Proteinen
SE522048C2 (sv) 2002-05-17 2004-01-07 Hemapure Ab Anordning och system för filtrering av blod
JP4587213B2 (ja) * 2002-06-17 2010-11-24 旭化成クラレメディカル株式会社 生体適合性ポリマーおよびそれを用いた白血球選択除去フィルター材
CA2535489C (en) * 2003-08-14 2014-09-30 D. Collen Research Foundation Vzw Antibodies against factor viii with modified glycosylation in the variable region
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DK1869171T4 (en) * 2005-04-11 2016-01-18 Crucell Holland Bv Virus cleaning using ultrafiltration
PL2242479T3 (pl) * 2007-12-28 2012-02-29 Baxalta Inc Filtracja białek z zastosowaniem przeciwciśnienia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004269529A (ja) 2003-03-06 2004-09-30 Probitas Pharma Sa フィブリノゲン溶液中のウイルスを除去する方法およびこの方法により得られるフィブリノゲン

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Journal of Membrane Science. 1993. vol. 80. pp131-145

Also Published As

Publication number Publication date
US20120136139A1 (en) 2012-05-31
PL2242479T3 (pl) 2012-02-29
AR116112A2 (es) 2021-03-31
ATE525062T1 (de) 2011-10-15
BRPI0821599A2 (pt) 2015-06-16
ES2377038T3 (es) 2012-03-21
PT2242479E (pt) 2011-11-25
US20090188862A1 (en) 2009-07-30
JP5925817B2 (ja) 2016-05-25
US20100314317A1 (en) 2010-12-16
SI2242479T1 (sl) 2012-01-31
EP2392317A1 (en) 2011-12-07
JP5027310B2 (ja) 2012-09-19
AU2008345218B2 (en) 2015-02-19
JP2011507962A (ja) 2011-03-10
JP2014166989A (ja) 2014-09-11
AR070061A1 (es) 2010-03-10
KR101915445B1 (ko) 2018-11-05
SG187411A1 (en) 2013-02-28
US8454833B2 (en) 2013-06-04
KR101748878B1 (ko) 2017-06-19
US7959809B2 (en) 2011-06-14
AU2008345218A1 (en) 2009-07-09
US20100317081A1 (en) 2010-12-16
CA2709781C (en) 2017-03-14
JP2012144578A (ja) 2012-08-02
DK2242479T3 (da) 2012-01-02
EP2242479A2 (en) 2010-10-27
KR20180028559A (ko) 2018-03-16
KR20170070255A (ko) 2017-06-21
CN101909599B (zh) 2012-11-21
WO2009086296A3 (en) 2009-08-27
KR20100106485A (ko) 2010-10-01
WO2009086296A2 (en) 2009-07-09
HK1150750A1 (en) 2012-01-13
HRP20110927T1 (hr) 2012-02-29
NZ586316A (en) 2012-06-29
JP5466263B2 (ja) 2014-04-09
CN101909599A (zh) 2010-12-08
CA2709781A1 (en) 2009-07-09
US8075781B2 (en) 2011-12-13
US8075782B2 (en) 2011-12-13
JP2016106131A (ja) 2016-06-16
EP2242479B1 (en) 2011-09-21
NZ600053A (en) 2013-06-28

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