DE69610227T2 - Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten - Google Patents

Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten

Info

Publication number
DE69610227T2
DE69610227T2 DE69610227T DE69610227T DE69610227T2 DE 69610227 T2 DE69610227 T2 DE 69610227T2 DE 69610227 T DE69610227 T DE 69610227T DE 69610227 T DE69610227 T DE 69610227T DE 69610227 T2 DE69610227 T2 DE 69610227T2
Authority
DE
Germany
Prior art keywords
blood
organic components
selective separation
invention pertains
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69610227T
Other languages
English (en)
Other versions
DE69610227D1 (de
Inventor
S Kent
N Drohan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Application granted granted Critical
Publication of DE69610227D1 publication Critical patent/DE69610227D1/de
Publication of DE69610227T2 publication Critical patent/DE69610227T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69610227T 1996-07-10 1996-12-20 Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten Expired - Lifetime DE69610227T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2154596P 1996-07-10 1996-07-10
PCT/US1996/020034 WO1998001464A1 (en) 1996-07-10 1996-12-20 Methods for the selective separation of organic components from biological fluids

Publications (2)

Publication Number Publication Date
DE69610227D1 DE69610227D1 (de) 2000-10-12
DE69610227T2 true DE69610227T2 (de) 2001-01-04

Family

ID=21804845

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69610227T Expired - Lifetime DE69610227T2 (de) 1996-07-10 1996-12-20 Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten

Country Status (8)

Country Link
US (1) US6193891B1 (de)
EP (1) EP0915906B1 (de)
AT (1) ATE196148T1 (de)
AU (1) AU1422597A (de)
DE (1) DE69610227T2 (de)
DK (1) DK0915906T3 (de)
ES (1) ES2149515T3 (de)
WO (1) WO1998001464A1 (de)

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AUPN030794A0 (en) 1994-12-22 1995-01-27 Aruba International Pty Ltd Discontinuous plasma or serum delipidation
US20020012990A1 (en) 1999-12-22 2002-01-31 Lander Russel Jackson Process for the scaleable purification of plasmid DNA
JP4856833B2 (ja) * 1999-12-22 2012-01-18 メルク・シャープ・エンド・ドーム・コーポレイション プラスミドｄｎａの大規模化可能な精製方法
US8597516B2 (en) * 2000-05-16 2013-12-03 Immunocept, L.L.C. Methods and systems for colloid exchange therapy
AUPQ846900A0 (en) * 2000-06-29 2000-07-27 Aruba International Pty Ltd A vaccine
US20090017069A1 (en) * 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
US7407663B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified immunodeficiency virus particles
US7439052B2 (en) * 2000-06-29 2008-10-21 Lipid Sciences Method of making modified immunodeficiency virus particles
US7407662B2 (en) * 2000-06-29 2008-08-05 Lipid Sciences, Inc. Modified viral particles with immunogenic properties and reduced lipid content
US20020164825A1 (en) * 2000-09-09 2002-11-07 Wen-Tien Chen Cell separation matrix
US6506308B1 (en) * 2000-09-12 2003-01-14 Advanced Minerals Corporation Methods for the removal of organic substances from aqueous solutions
WO2002092161A1 (en) * 2001-05-10 2002-11-21 Biophan, Llc Miniaturized particle analyzer
WO2003000373A1 (en) * 2001-06-25 2003-01-03 Lipid Sciences, Inc. Systems and methods using a solvent for the removal of lipids from fluids
US20030127386A1 (en) * 2001-06-25 2003-07-10 Bomberger David C. Hollow fiber contactor systems for removal of lipids from fluids
US6991727B2 (en) * 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US20060060520A1 (en) * 2001-06-25 2006-03-23 Bomberger David C Systems and methods using a solvent for the removal of lipids from fluids
AU2002322284A1 (en) * 2001-06-25 2003-01-08 Lipid Sciences, Inc. Systems and methods using multiple solvents for the removal of lipids from fluids
WO2003035888A1 (en) * 2001-08-28 2003-05-01 Wen-Tien Chen Cell separation matrix
ES2299602T3 (es) * 2001-10-04 2008-06-01 Toray Industries, Inc. Sustancia hidrofilica y procedimiento de obtencion de la misma.
US20030201229A1 (en) * 2002-02-04 2003-10-30 Martin Siwak Process for prefiltration of a protein solution
AU2003212912A1 (en) * 2002-02-04 2003-09-02 Millipore Corporation Process for removing protein aggregates and virus from a protein solution
US20040106556A1 (en) * 2002-08-26 2004-06-03 Yanhong Zhu Method of treating and preventing alzheimer disease through administration of delipidated protein and lipoprotein particles
US20050042772A1 (en) * 2003-02-07 2005-02-24 Beyond Genomics Removal of proteins from a sample
US20040245124A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
US20040245144A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
EP2368565B1 (de) * 2003-07-03 2015-06-24 HDL Therapeutics, Inc. Anreicherung von pre-beta high density Lipoproteinen
US7393826B2 (en) 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US6960803B2 (en) * 2003-10-23 2005-11-01 Silicon Storage Technology, Inc. Landing pad for use as a contact to a conductive spacer
FR2869995B1 (fr) * 2004-05-10 2006-09-22 Sebia Sa Procede ameliore de separation de proteines par electrophorese capillaire et compositions de tampon pour electrophorese capillaire
US20080028989A1 (en) * 2006-07-20 2008-02-07 Scott Kevin Palm Process for removing organic contaminants from non-metallic inorganic materials using dielectric heating
US20080119350A1 (en) * 2006-11-20 2008-05-22 Korea Institute Of Geosciences And Mineral Resources Ion exchange type lithium adsorbent using filter and method for preparing the same
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
EP2242479B1 (de) * 2007-12-28 2011-09-21 Baxter International Inc. Gegendruckfiltration von proteinen
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
WO2012139017A1 (en) 2011-04-07 2012-10-11 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
KR101446265B1 (ko) * 2011-10-17 2014-11-03 메디칸(주) 면역성이 제거된 생체지방소재 및 이의 제조방법
DE102014210662A1 (de) 2014-06-04 2015-12-17 Gea Westfalia Separator Group Gmbh Vorrichtung und Verfahren zur Gewinnung von Glycoglycerolipiden und Glycosphingolipiden aus lipoiden Phasen
CN105153297B (zh) * 2015-09-17 2020-03-31 中国人民解放军军事医学科学院野战输血研究所 一种从Cohn组分Ⅳ沉淀中分离纯化α2-巨球蛋白的方法
CN115925781A (zh) * 2015-10-15 2023-04-07 普莱泽玛科技有限公司 从血浆中提取蛋白质的方法
CN111868232B (zh) 2017-11-22 2024-05-28 Hdl治疗公司 用于对血浆处理系统的流体回路进行灌注的系统和方法
CA3087207A1 (en) 2017-12-28 2019-07-04 Hdl Therapeutics, Inc. Methods for preserving and administering pre-beta high density lipoprotein extracted from human plasma
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
KR20220111307A (ko) * 2019-12-03 2022-08-09 옴릭스 바이오파머슈티컬스 리미티드 프로-트롬빈 정제

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US2539397A (en) 1947-03-26 1951-01-30 Nat Cylinder Gas Co Purification of sugar solutions
US3099626A (en) 1958-12-31 1963-07-30 Johns Manville Sweetener for dry cleaners' solvents
DE2239254C2 (de) 1970-12-30 1983-08-04 Organon Teknika Corp., Oklahoma City, Okla. "Säule zur Regenerierung einer zirkulierenden Dialysatlösung und Verwendung dieser Säule".
JPS5327491A (en) * 1976-08-26 1978-03-14 Terumo Corp Separation and refining process for red corpuscle
US4112129A (en) * 1977-09-14 1978-09-05 Johns-Manville Corporation Cooking oil treating system and composition therefor
JPS5545458A (en) * 1978-09-29 1980-03-31 Kyowa Kagaku Kogyo Kk Adsorbent for purifying blood
US4399164A (en) 1979-01-26 1983-08-16 Nutrisearch Company Preparation of a dried blend of whey by-product and casein or its salts
US4384954A (en) * 1980-04-16 1983-05-24 Kuraray Co., Ltd. Column for adsorption of blood proteins
JPS5810056A (ja) * 1981-07-10 1983-01-20 株式会社クラレ 血液浄化装置
FR2561074B1 (fr) 1984-03-15 1986-10-31 Lille I Universite Sciences Te Procede de decoloration de substances colorees par des composes tetrapyrroliques, et produits obtenus
US5037649A (en) * 1985-01-11 1991-08-06 Imre Corporation Method for treatment of HIV-infected patients
CA1259915A (en) * 1985-10-09 1989-09-26 Sailen S. Mookerjea Means to reduce plasma cholesterol
US5252762A (en) 1991-04-03 1993-10-12 W. R. Grace & Co.-Conn. Use of base-treated inorganic porous adsorbents for removal of contaminants
ES2087831B1 (es) 1994-12-22 1997-04-01 Tolsa Sa Nueva litera absorbente a base de sepiolita para animales y procedimiento para su preparacion.
US6008040A (en) * 1995-07-07 1999-12-28 Synosys, Inc. Procedures for efficient separation of cells, cellular materials and proteins

Also Published As

Publication number Publication date
EP0915906B1 (de) 2000-09-06
WO1998001464A1 (en) 1998-01-15
DK0915906T3 (da) 2000-11-20
AU1422597A (en) 1998-02-02
US6193891B1 (en) 2001-02-27
ATE196148T1 (de) 2000-09-15
EP0915906A1 (de) 1999-05-19
DE69610227D1 (de) 2000-10-12
ES2149515T3 (es) 2000-11-01

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