JP5027310B2 - タンパク質の逆圧濾過 - Google Patents

タンパク質の逆圧濾過 Download PDF

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Publication number
JP5027310B2
JP5027310B2 JP2010540839A JP2010540839A JP5027310B2 JP 5027310 B2 JP5027310 B2 JP 5027310B2 JP 2010540839 A JP2010540839 A JP 2010540839A JP 2010540839 A JP2010540839 A JP 2010540839A JP 5027310 B2 JP5027310 B2 JP 5027310B2
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JP
Japan
Prior art keywords
pressure
filtrate
filter
protein
mixture
Prior art date
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Active
Application number
JP2010540839A
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English (en)
Japanese (ja)
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JP2011507962A (ja
JP2011507962A5 (https=
Inventor
ネボイザ ニコリク，
ミカエラ フレイ，
ウォルフガング グラブマイアー，
トーマス ヤンツィク，
マティアス フリード，
クラウス ツシェツシュコウィッシュ，
クルト シュネッカー，
バーバラ リーグラー，
アルマ カサポヴィック，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare SA
Baxter International Inc
Original Assignee
Baxter Healthcare SA
Baxter International Inc
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Publication date
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Application filed by Baxter Healthcare SA, Baxter International Inc filed Critical Baxter Healthcare SA
Publication of JP2011507962A publication Critical patent/JP2011507962A/ja
Publication of JP2011507962A5 publication Critical patent/JP2011507962A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010540839A 2007-12-28 2008-12-22 タンパク質の逆圧濾過 Active JP5027310B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1741807P 2007-12-28 2007-12-28
US61/017,418 2007-12-28
PCT/US2008/088005 WO2009086296A2 (en) 2007-12-28 2008-12-22 Counter-pressure filtration of proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012105696A Division JP5466263B2 (ja) 2007-12-28 2012-05-07 タンパク質の逆圧濾過

Publications (3)

Publication Number Publication Date
JP2011507962A JP2011507962A (ja) 2011-03-10
JP2011507962A5 JP2011507962A5 (https=) 2012-02-02
JP5027310B2 true JP5027310B2 (ja) 2012-09-19

Family

ID=40602549

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2010540839A Active JP5027310B2 (ja) 2007-12-28 2008-12-22 タンパク質の逆圧濾過
JP2012105696A Active JP5466263B2 (ja) 2007-12-28 2012-05-07 タンパク質の逆圧濾過
JP2014009986A Active JP5925817B2 (ja) 2007-12-28 2014-01-23 タンパク質の逆圧濾過
JP2016040641A Pending JP2016106131A (ja) 2007-12-28 2016-03-03 タンパク質の逆圧濾過

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2012105696A Active JP5466263B2 (ja) 2007-12-28 2012-05-07 タンパク質の逆圧濾過
JP2014009986A Active JP5925817B2 (ja) 2007-12-28 2014-01-23 タンパク質の逆圧濾過
JP2016040641A Pending JP2016106131A (ja) 2007-12-28 2016-03-03 タンパク質の逆圧濾過

Country Status (18)

Country Link
US (4) US7959809B2 (https=)
EP (2) EP2392317A1 (https=)
JP (4) JP5027310B2 (https=)
KR (3) KR101839278B1 (https=)
CN (1) CN101909599B (https=)
AR (2) AR070061A1 (https=)
AT (1) ATE525062T1 (https=)
AU (1) AU2008345218B2 (https=)
CA (1) CA2709781C (https=)
DK (1) DK2242479T3 (https=)
ES (1) ES2377038T3 (https=)
HR (1) HRP20110927T1 (https=)
NZ (2) NZ600053A (https=)
PL (1) PL2242479T3 (https=)
PT (1) PT2242479E (https=)
SG (1) SG187411A1 (https=)
SI (1) SI2242479T1 (https=)
WO (1) WO2009086296A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014166989A (ja) * 2007-12-28 2014-09-11 Baxter Internatl Inc タンパク質の逆圧濾過

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI469992B (zh) * 2008-08-28 2015-01-21 Baxter Int 濃縮剪切靈敏生物聚合物的方法
US10100594B2 (en) * 2013-06-27 2018-10-16 Ge Oil & Gas Uk Limited Control system and a method for monitoring a filter in an underwater hydrocarbon well
ES2916825T3 (es) * 2014-01-20 2022-07-06 UCB Biopharma SRL Procedimiento para la reconstitución de una forma sólida de una composición farmacéutica

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Publication number Priority date Publication date Assignee Title
DE2624373C2 (de) * 1976-05-31 1983-02-03 Arnold Dr. 8782 Karlstadt Seufert Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII
US5047154A (en) * 1983-03-10 1991-09-10 C.P.C. Engineering Company Method and apparatus for enhancing the flux rate of cross-flow filtration systems
SE443075B (sv) * 1984-06-01 1986-02-17 Alfa Laval Agri Int Forfarande och anordning for framstellning av mjolkkoncentrat genom membranfiltrering
ATE64956T1 (de) * 1984-06-14 1991-07-15 Ciba Geigy Ag Verfahren zur herstellung von thrombininhibitoren.
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
US4774323A (en) * 1987-06-29 1988-09-27 Rorer Pharmaceutical Corporation Purification of von Willebrand Factor solutions using gel permeation chromatography
DE3730868A1 (de) 1987-09-15 1989-03-23 Henkel Kgaa Verfahren zur abtrennung von biotechnisch hergestellten wertstoffen aus einer fermenterbruehe durch querstrom-mikro- und/oder ultrafiltration
SE9003452L (sv) 1990-10-30 1992-05-01 Teinvall Sjoeberg & Broberg Ab Saett och anordning vid vaetskefiltrering
CH687055A5 (de) * 1993-12-03 1996-09-13 Bucher Guyer Ag Masch Verfahren und Vorrichtung zum Eindicken von Fest/Fluessig-Gemischen mittels Membrantechnologie.
US5525144A (en) * 1995-04-20 1996-06-11 A/G Technology Corporation Tangential flow filtering and separating
AT403764B (de) * 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
DE69610227T2 (de) * 1996-07-10 2001-01-04 American National Red Cross, Washington Verfahren zur selektiver trennung organischer komponenten aus biologischen flüssigkeiten
US5888401A (en) * 1996-09-16 1999-03-30 Union Camp Corporation Method and apparatus for reducing membrane fouling
AT406867B (de) * 1997-02-27 2000-10-25 Immuno Ag Verfahren zur gewinnung von hochreinem vwf oder faktor viii/vwf-komplex
US5947689A (en) * 1997-05-07 1999-09-07 Scilog, Inc. Automated, quantitative, system for filtration of liquids having a pump controller
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
US6139878A (en) 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
MXPA01002908A (es) * 1998-09-21 2002-04-08 E Purdum Howard Metodos y aparatos para procesar materiales sensibles a la temperatura.
DE19906379B4 (de) * 1999-02-16 2006-05-18 Huss, Manfred Herstellung eines aggregierten Molkenproteinprodukts
US6623781B2 (en) 1999-07-26 2003-09-23 Cornell Research Foundation, Inc. Microfiltration of skim milk for cheese making and whey proteins
US6485762B1 (en) * 1999-07-26 2002-11-26 Cornell Research Foundation, Inc. Microfiltration of skim milk for cheese making and whey proteins
DE10211227A1 (de) * 2002-03-13 2003-10-02 Aventis Behring Gmbh Verfahren zur Rekonstitution von Iyophilisierten Proteinen
SE522048C2 (sv) 2002-05-17 2004-01-07 Hemapure Ab Anordning och system för filtrering av blod
JP4587213B2 (ja) * 2002-06-17 2010-11-24 旭化成クラレメディカル株式会社 生体適合性ポリマーおよびそれを用いた白血球選択除去フィルター材
ES2214967B1 (es) 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
CA2535489C (en) * 2003-08-14 2014-09-30 D. Collen Research Foundation Vzw Antibodies against factor viii with modified glycosylation in the variable region
FR2861395B1 (fr) 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
DK1869171T4 (en) * 2005-04-11 2016-01-18 Crucell Holland Bv Virus cleaning using ultrafiltration
PL2242479T3 (pl) * 2007-12-28 2012-02-29 Baxalta Inc Filtracja białek z zastosowaniem przeciwciśnienia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014166989A (ja) * 2007-12-28 2014-09-11 Baxter Internatl Inc タンパク質の逆圧濾過

Also Published As

Publication number Publication date
US20120136139A1 (en) 2012-05-31
PL2242479T3 (pl) 2012-02-29
AR116112A2 (es) 2021-03-31
ATE525062T1 (de) 2011-10-15
BRPI0821599A2 (pt) 2015-06-16
ES2377038T3 (es) 2012-03-21
PT2242479E (pt) 2011-11-25
US20090188862A1 (en) 2009-07-30
JP5925817B2 (ja) 2016-05-25
US20100314317A1 (en) 2010-12-16
SI2242479T1 (sl) 2012-01-31
EP2392317A1 (en) 2011-12-07
AU2008345218B2 (en) 2015-02-19
JP2011507962A (ja) 2011-03-10
JP2014166989A (ja) 2014-09-11
AR070061A1 (es) 2010-03-10
KR101915445B1 (ko) 2018-11-05
SG187411A1 (en) 2013-02-28
US8454833B2 (en) 2013-06-04
KR101748878B1 (ko) 2017-06-19
US7959809B2 (en) 2011-06-14
AU2008345218A1 (en) 2009-07-09
US20100317081A1 (en) 2010-12-16
CA2709781C (en) 2017-03-14
JP2012144578A (ja) 2012-08-02
DK2242479T3 (da) 2012-01-02
EP2242479A2 (en) 2010-10-27
KR20180028559A (ko) 2018-03-16
KR20170070255A (ko) 2017-06-21
CN101909599B (zh) 2012-11-21
WO2009086296A3 (en) 2009-08-27
KR20100106485A (ko) 2010-10-01
WO2009086296A2 (en) 2009-07-09
HK1150750A1 (en) 2012-01-13
HRP20110927T1 (hr) 2012-02-29
NZ586316A (en) 2012-06-29
JP5466263B2 (ja) 2014-04-09
CN101909599A (zh) 2010-12-08
CA2709781A1 (en) 2009-07-09
US8075781B2 (en) 2011-12-13
KR101839278B1 (ko) 2018-03-15
US8075782B2 (en) 2011-12-13
JP2016106131A (ja) 2016-06-16
EP2242479B1 (en) 2011-09-21
NZ600053A (en) 2013-06-28

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