KR101816511B1 - 신규한 비브리오 앵길라룸 박테리오파지 Ｖｉｂ-ＡＮＰ-1 및 이의 비브리오 앵길라룸 균 증식 억제 용도 - Google Patents

신규한 비브리오 앵길라룸 박테리오파지 Ｖｉｂ-ＡＮＰ-1 및 이의 비브리오 앵길라룸 균 증식 억제 용도 Download PDF

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KR101816511B1
KR101816511B1 KR1020160112908A KR20160112908A KR101816511B1 KR 101816511 B1 KR101816511 B1 KR 101816511B1 KR 1020160112908 A KR1020160112908 A KR 1020160112908A KR 20160112908 A KR20160112908 A KR 20160112908A KR 101816511 B1 KR101816511 B1 KR 101816511B1
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vibrio
bacteriophage
anp
vib
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윤성준
전수연
권안성
황순혜
송현민
정지인
강상현
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주식회사 인트론바이오테크놀로지
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Abstract

본 발명은 비브리오 앵길라룸 균을 특이적으로 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 시포비리대 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP), 및 이를 유효성분으로 포함하는 조성물을 이용한 비브리오 앵길라룸 균의 감염을 방지 및 비브리오 앵길라룸 균의 감염을 치료하는 방법에 관한 것이다.

Description

신규한 비브리오 앵길라룸 박테리오파지 Ｖｉｂ-ＡＮＰ-1 및 이의 비브리오 앵길라룸 균 증식 억제 용도{Novel Vibrio anguillarum bacteriophage Vib-ANP-1 and its use for preventing proliferation of Vibrio anguillarum}
본 발명은 비브리오 앵길라룸 균에 감염하여 비브리오 앵길라룸 균을 사멸시킬 수 있는 자연으로부터 분리한 박테리오파지 및 이를 유효성분으로 포함한 조성물을 이용한 비브리오 앵길라룸 균의 감염을 방지 및 처치하는 방법에 관한 것으로, 더욱 상세하게는 비브리오 앵길라룸 균을 특이적으로 사멸시킬 수 있는 능력을 갖는 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 시포비리대 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP), 및 상기 박테리오파지를 유효성분으로 포함하는 조성물을 이용한 비브리오 앵길라룸 균의 감염 방지 및 감염 후 처치 방법에 관한 것이다.
비브리오 속(Genus)에 속하는 비브리오 앵길라룸(Vibrio anguillarum)은 그람음성 간균으로 넙치를 비롯하여 연어과 어류, 뱀장어, 및 각종 해산어에 있어 출혈성 패혈증(Hemorrhagic septicemia)을 수반하는 비브리오병(Vibriosis)을 유발하는 대표적인 어류 병원세균으로 알려져 있다. 비브리오 앵길라룸 균의 항원형(Serotype)은 현재까지 23 종류의 항원형이 있다고 밝혀졌지만, 어류 비브리오병을 야기하는 비브리오 앵길라룸 병원성 균주 대부분은 균체항원(Somatic, O 항원)인 O1 항원형과 O2 항원형인 것으로 알려졌다.
비브리오 앵길라룸 균은 다양한 어류에서 비브리오병을 유발하여 수산 양식 산업에 있어 심각한 경제적 피해를 초래하고 있다. 특히 비브리오 앵길라룸 균 감염에 의한 어류의 비브리오병은 그 발병 빈도가 높기 때문에 경제적 피해 초래가 크다. 따라서 비브리오 앵길라룸 균 감염을 예방하고 나아가 감염 처치에까지 활용될 수 있는 방안의 개발이 절실한 실정이다.
비브리오 앵길라룸 균에 의한 감염 억제 및 치료를 위해 항생제가 널리 사용되고 있는데, 최근 항생제 내성균의 증가로 인해 그 효과는 계속 떨어지고 있으며 양식 어류에의 항생제 사용에 대한 규제 강화로 항생제 외의 다른 효과적 방법의 개발이 요구되고 있는 실정이다. 특히 자연 친화적 방법에 대한 요구가 크다.
최근 세균성 질환의 대처 방안으로 박테리오파지(Bacteriophage)의 활용이 크게 주목을 받고 있다. 특히 자연친화적 방식의 선호로 인하여 박테리오파지에 대한 관심은 어느 때보다 높다고 할 수 있다. 박테리오파지는 세균에 감염하는 아주 작은 미생물로서 보통 파지(Phage)라고 줄여서 부르기도 한다. 박테리오파지는 박테리아에 감염(Infection)한 후 박테리아 세포 내부에서 증식을 하고, 증식 후 자손 박테리오파지들이 박테리아 밖으로 나올 때 숙주인 박테리아의 세포벽을 파괴하는 방식으로 박테리아를 사멸시키는 능력을 갖고 있다.
박테리오파지의 박테리아 감염 방식은 매우 특이성이 높아서 특정 박테리아에 감염할 수 있는 박테리오파지의 종류는 일부로 한정된다. 즉, 특정 박테리오파지는 특정 범주의 박테리아에만 감염할 수 있고 이로 인하여 특정 박테리오파지는 특정 박테리아만을 사멸시키며 다른 박테리아에는 영향을 주지 않는다. 이러한 박테리오파지의 세균 특이성으로 인하여 박테리오파지는 목적으로 하는 세균에 대해서만 항균효과를 제공하고 환경이나 어류 내의 상재균들에는 영향을 초래하지 않는다. 통상적으로 세균 처치에 널리 활용되던 기존의 항생제들은 여러 종류의 세균들에 대하여 동시에 영향을 끼쳤다. 이로 인하여 환경오염이나 동물의 체내 정상 세균총(Normal flora) 교란 등의 문제를 초래하였다. 이와는 달리 박테리오파지는 특정 세균에 대해서만 작동하므로 박테리오파지 사용에 의해서 체내 정상 세균총 교란 등이 발생하지 않는다. 따라서 그 사용이 항생제 사용에 비교하여 매우 안전하다고 할 수 있고 그 만큼 사용에 의한 부작용 초래 가능성이 상대적으로 크게 낮다.
박테리오파지는 1915년 영국의 세균학자 Twort가 포도상구균(Micrococcus) 집락이 어떤 것에 의해 투명하게 녹는 현상에 대한 연구를 수행하면서 발견되었다. 또한, 1917년에는 프랑스의 세균학자 d'Herelle이 이질환자 변의 여과액 중에 적리균(Shigella dysenteriae)을 녹이는 작용을 가진 것이 있다는 것을 발견하고 이에 대한 연구를 통해 독립적으로 박테리오파지를 발견하였으며, 세균을 잡아먹는다는 뜻에서 박테리오파지라고 명명하였다. 이후 이질균, 장티푸스균, 콜레라균 등 여러 병원성 박테리아에 대한 박테리오파지가 계속적으로 발견되었다.
박테리아를 사멸시킬 수 있는 특별한 능력으로 인하여 박테리오파지는 발견 이후 박테리아 감염에 대응하는 효과적 방안으로 기대를 모았으며 관련하여 많은 연구들이 있었다. 그러나 Fleming에 의해 페니실린이 발견된 이후, 항생제의 보급이 일반화되면서 박테리오파지에 대한 연구는 일부 동유럽 국가들 및 구소련에 한정되어서만 명맥이 유지되었다. 그런데 2000년 이후에 항생제 내성균의 증가로 인하여 기존 항생제의 한계성이 나타나고, 기존 항생제의 대체 물질로의 개발 가능성이 부각되면서 다시 박테리오파지가 항-박테리아제로 주목을 받고 있다. 특히 최근 항생제 사용에 대한 정부 차원의 규제가 전 세계적으로 강화됨에 따라 박테리오파지에 대한 관심이 더욱 높아지고 있으며 산업적 활용 사례도 점차 증가하고 있다.
앞에서 설명했듯이 박테리오파지는 세균에 대한 특이성이 매우 높다. 이러한 특이성으로 인하여 박테리오파지는 동일 종(Species)에 속하는 세균들이라 할지라도 그 일부 주(Strain)에 대해서만 항균효과를 발휘하는 경우가 많다. 또한 박테리오파지가 다름에 따라 동일 세균 주에 대하여 발휘되는 박테리오파지의 항균력 세기 자체도 다를 수 있다. 이러한 이유로 특정 종의 세균에 대하여 효과적 제어법을 확보하려면 다양한 종류의 유용 박테리오파지들의 확보가 필요하다. 비브리오 앵길라룸 균에 대응하여 효과적인 박테리오파지 활용법을 개발하기 위해서도 당연히 비브리오 앵길라룸 균에 대하여 항균효과를 제공할 수 있는 여러 종류의 다양한 유용 박테리오파지들의 확보가 필요하고, 더 나아가 확보한 다양한 유용 박테리오파지들 중에서 항균력의 세기나 항균범위 측면에서 비교우위에 있는 박테리오파지의 선발 활용도 필요하다.
이에, 본 발명자들은 비브리오 앵길라룸 균을 선택적으로 사멸시킬 수 있는 자연으로부터 분리된 박테리오파지를 이용하여 비브리오 앵길라룸 균의 감염을 방지 또는 처치하는 데에 활용될 수 있는 조성물을 개발하고, 또 이 조성물을 이용하여 비브리오 앵길라룸 균의 감염을 방지 또는 처치하는 방법을 개발하고자 노력한 끝에, 이에 적합한 박테리오파지를 자연으로부터 분리하고 이 분리된 박테리오파지를 타 박테리오파지와 구별하여 특정 지을 수 있도록 유전체(Genome)의 유전자 서열을 확보한 후 상기 박테리오파지를 유효성분으로 한 조성물을 개발한 다음 이 조성물이 비브리오 앵길라룸 균의 감염 방지 및 처치에 효과적으로 활용될 수 있음을 확인함으로써 본 발명을 완성하였다.
따라서 본 발명의 목적은 비브리오 앵길라룸 균을 특이적으로 사멸시킬 수 있는 능력을 갖는 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 시포비리대(Siphoviridae) 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP)을 제공하는 것이다.
본 발명의 또 다른 목적은 비브리오 앵길라룸 균에 감염하여 비브리오 앵길라룸 균을 사멸시킬 수 있는 박테리오파지 Vib-ANP-1을 유효성분으로 포함하는 비브리오 앵길라룸 균의 감염을 방지하는 데에 활용 가능한 조성물 및 이 조성물을 이용한 비브리오 앵길라룸 균의 감염 방지 방법을 제공하는 것이다.
본 발명의 또 다른 목적은 비브리오 앵길라룸 균에 감염하여 비브리오 앵길라룸 균을 사멸시킬 수 있는 박테리오파지 Vib-ANP-1을 유효성분으로 포함하는 비브리오 앵길라룸 균의 감염을 처치하는 데에 활용 가능한 조성물 및 이 조성물을 이용한 비브리오 앵길라룸 균의 감염 처치 방법을 제공하는 것이다.
본 발명의 또 다른 목적은 상기 조성물들을 이용한 비브리오 앵길라룸 균의 감염 방지 및 처치 목적의 약욕제를 제공하는 것이다.
본 발명의 또 다른 목적은 상기 조성물들을 이용한 비브리오 앵길라룸 균의 감염 방지 및 처치를 통한 사양 효과 제공 목적의 사료첨가제를 제공하는 것이다.
본 발명은 비브리오 앵길라룸 균을 특이적으로 사멸시킬 수 있는 능력을 갖는 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 시포비리대 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP), 및 이를 유효성분으로 포함하는 조성물을 이용한 비브리오 앵길라룸 균의 감염 방지 및 처치 방법을 제공한다.
박테리오파지 Vib-ANP-1은 본 발명자들에 의해 분리된 후 2016년 8월 16일자로 한국생명공학연구원 생물자원센터에 기탁되었다(수탁번호 KCTC 13075BP).
또한, 본 발명은 비브리오 앵길라룸 균의 감염을 방지 또는 처치하는 데에 활용될 수 있는 박테리오파지 Vib-ANP-1을 유효성분으로 포함하는 약욕제 및 사료첨가제를 제공한다.
본 발명의 조성물에 포함되는 박테리오파지 Vib-ANP-1은 비브리오 앵길라룸 균을 효과적으로 사멸시키므로 비브리오 앵길라룸 균에 의해 유발되는 질환의 예방(감염 방지)이나 치료(감염 처치)에 효과를 나타낸다. 따라서 본 발명의 조성물은 비브리오 앵길라룸 균에 의해 유발되는 질환에 대한 예방 및 치료 목적으로 활용될 수 있다.
본 명세서에서 사용된 “방지” 또는 “예방”이라는 용어는 (ⅰ) 비브리오 앵길라룸 균 감염의 방지; 및 (ⅱ) 비브리오 앵길라룸 균 감염에 의한 질병으로의 발전을 억제하는 것을 의미한다.
또한, 본 명세서에서 사용된 “처치” 또는 “치료”라는 용어는 (ⅰ) 비브리오 앵길라룸 균에 의해 유발된 질환의 억제; 및 (ⅱ) 비브리오 앵길라룸 균에 의해 유발된 질환의 병적 상태를 경감시키는 모든 행위를 의미한다.
본 명세서의 “분리”, “분리한” 또는 “분리된”은 자연 상태로부터 여러 실험 기법을 활용하여 박테리오파지를 분리하는 것과 타 박테리오파지와 구별하여 대상 박테리오파지를 특정 지을 수 있는 특징들을 확보하는 것을 지칭하며, 이에 더하여 생물공학기술로 대상 박테리오파지를 산업적으로 활용할 수 있게끔 증식시키는 것도 포함한다.
본 발명의 조성물에 포함되는 약제학적으로 허용되는 담체는 제제 시에 통상적으로 이용되는 것으로서, 락토오스, 덱스트로오스, 수크로오스, 솔비톨, 만니톨, 전분, 아카시아 고무, 인산칼슘, 알지네이트, 젤라틴, 규산칼슘, 미세결정성 셀룰로오스, 폴리비닐피롤리돈, 셀룰로오스, 물, 시럽, 메틸 셀룰로오스, 메틸히드록시벤조에이트, 프로필히드록시벤조에이트, 활석, 스테아르산 마그네슘 및 미네랄 오일 등을 포함하나, 이에 한정되는 것은 아니다. 본 발명의 조성물은 상기 성분들 이외에 윤활제, 습윤제, 감미제, 향미제, 유화제, 현탁제, 보존제 등을 추가로 포함할 수 있다.
본 발명의 조성물에는 박테리오파지 Vib-ANP-1이 유효성분으로 포함된다. 이때 포함되는 박테리오파지 Vib-ANP-1은 1× 101 pfu/㎖ 내지 1× 1030 pfu/㎖ 또는 1× 101 pfu/g 내지 1× 1030 pfu/g로 포함되며, 바람직하게는 1× 104 pfu/㎖ 내지 1× 1015 pfu/㎖ 또는 1× 104 pfu/g 내지 1× 1015 pfu/g로 포함된다.
본 발명의 조성물은 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자가 용이하게 실시할 수 있는 방법에 따라, 약학적으로 허용되는 담체 및/또는 부형제를 이용하여 제제화 됨으로써 단위 용량 형태로 제조되거나 또는 다용량 용기 내에 내입시켜 제조될 수도 있다. 이때 제형은 오일 또는 수성 매질 중의 용액, 현탁액 또는 유화액 형태이거나 엑스제, 분말제, 과립제, 정제 또는 캡슐제 형태일 수도 있으며, 분산제 또는 안정화제를 추가적으로 포함할 수도 있다.
본 발명의 조성물은 활용 방식에 따라, 이에 국한되지 않지만, 약욕제 및 사료첨가제로 구현될 수 있다.
이러한 활용 목적에서의 효율성을 높이기 위하여 다른 세균종에 대하여 항균활성을 제공할 수 있는 박테리오파지들이 본 발명의 조성물에 추가될 수 있다. 또한, 비브리오 앵길라룸 균에 대하여 항균활성을 갖는 다른 종류의 박테리오파지들도 추가될 수 있다. 비브리오 앵길라룸 균에 대하여 항균활성을 갖는 박테리오파지라 하더라도 항균력의 세기나 항균범위 측면에서 서로 간에 차이가 있으므로 이들의 적절한 조합은 그 효과를 극대화 할 수 있다.
본 발명의 박테리오파지 Vib-ANP-1을 유효성분으로 포함하는 조성물을 이용한 비브리오 앵길라룸 균의 감염 방지 및 처치 방법은 기존의 항생제 등의 화학물질에 기반을 둔 방식에 비하여 비브리오 앵길라룸 균에 대한 특이성이 매우 높다는 장점을 제공할 수 있다. 이는 다른 유용한 상재균에는 영향을 주지 않으면서도 비브리오 앵길라룸 균의 감염 방지 또는 처치 목적으로 사용될 수 있음을 의미하며, 이의 사용에 따른 부작용이 매우 적다는 것을 의미한다. 통상적으로 항생제 등의 화학물질을 사용하면 일반 상재균들도 피해를 함께 입게 되어 결과적으로 동물에 면역력 저하 등을 초래하여 사용에 따른 다양한 부작용이 나타날 수 있다. 또한, 본 발명은 자연계에 이미 존재하는 박테리오파지를 분리하여 조성물의 유효성분으로 사용하기 때문에 매우 자연 친화적이라는 장점도 제공할 수 있다. 한편, 박테리오파지는 항균활성을 발휘할 수 있는 세균 종이 같다 하더라도 항균효과 발휘에 있어 항균력의 세기나 항균범위[비브리오 앵길라룸 균에 속하는 여러 세균 주(Strain)의 측면에서 개별 세균 주에 대하여 박테리오파지의 항균활성이 발휘되는 범위. 통상적으로 박테리오파지는 같은 세균 종(Species)에 속하는 일부 세균 주(Strain)에 대하여 항균활성을 발휘할 수 있음. 즉, 같은 세균 종에 속한다 하더라도 개별 세균 주에 따라 박테리오파지에 대한 감수성에서 차이가 있을 수 있음] 측면에서 차이가 있으므로 본 발명은 비브리오 앵길라룸 균에 대한 항균력을 갖는 타 박테리오파지에 비교하여 차별적 항균효과를 제공할 수 있다. 이는 산업현장 활용 시에 그 효과에 있어 큰 차이를 제공한다.
도 1은 박테리오파지 Vib-ANP-1의 전자현미경 사진이다.
도 2는 박테리오파지 Vib-ANP-1의 비브리오 앵길라룸 균에 대한 사멸능을 보여주는 실험 결과이다. 평판배지의 가운데 선을 기준으로 왼쪽은 박테리오파지 Vib-ANP-1이 포함되지 않은 완충액(Buffer)만을 점적한 것이고, 오른쪽은 박테리오파지 Vib-ANP-1이 포함된 액을 점적한 것이다. 오른쪽에서 관찰되는 투명한 부분은 시험대상 박테리아가 박테리오파지 Vib-ANP-1의 작용에 의하여 용균되어 결과적으로 형성된 용균반이다.
이하, 실시예에 의거하여 본 발명을 보다 구체적으로 설명하지만, 이들 실시예는 본 발명의 예시일 뿐이며 본 발명의 범위가 이들 실시예에 한정되는 것은 아니다.
실시예 1: 비브리오 앵길라룸 균을 사멸시킬 수 있는 박테리오파지의 분리
비브리오 앵길라룸 균을 사멸시킬 수 있는 박테리오파지의 분리에는 자연 환경으로부터 확보된 시료들을 이용하였다. 한편, 박테리오파지 분리에 사용된 비브리오 앵길라룸 균주들은 본 발명자들에 의해 미리 분리되어 비브리오 앵길라룸 균으로 동정(Identification)된 것들이다.
박테리오파지 분리 과정을 상세히 설명하면, 비브리오 앵길라룸 균을 1/1,000 비율로 접종한 LB(Luria-Bertani) 배지(트립톤, 10 g/L; 효모 추출물, 5 g/L; 염화 나트륨, 10 g/L)에 수집된 시료를 함께 첨가한 다음 30℃에서 3-4시간동안 진탕배양 하였다. 배양 후, 8,000 rpm에서 20분간 원심분리하여 상등액을 회수하였다. 회수된 상등액에 비브리오 앵길라룸 균을 1/1,000 비율로 접종한 다음 30℃에서 3-4시간동안 또 다시 진탕배양 하였다. 박테리오파지가 시료에 포함되어 있었을 경우에는 박테리오파지의 수(Titer)가 충분히 증가될 수 있도록 이러한 과정을 총 5회 반복 실시하였다. 5회 반복 실시 후에 배양액을 8,000 rpm에서 20분간 원심분리 하였다. 원심분리 후, 회수된 상등액에 대하여 0.45 ㎛의 필터를 이용하여 여과를 실시해 주었다. 이렇게 하여 얻어진 여과액을 사용한 통상의 점적 실험(Spot assay)을 통하여 비브리오 앵길라룸 균을 사멸시킬 수 있는 박테리오파지가 있는지를 조사하였다.
상기 점적 실험은 다음과 같이 실시하였다. LB 배지에 비브리오 앵길라룸 균을 1/1,000 비율로 접종한 다음 30℃에서 한밤동안 진탕배양 하였다. 이렇게 하여 준비된 비브리오 앵길라룸 균의 배양액 3 ㎖(OD600이 1.5)을 LA(Luria-Bertani Agar) 평판배지(트립톤, 10 g/L; 효모 추출물, 5 g/L; 염화 나트륨, 10 g/L; 아가, 15 g/L)에 도말(Spreading)하였다. 도말한 평판배지를 클린벤치(Clean bench)에서 약 30분 정도 방치하여 도말액이 건조되게 하였다. 건조 후 앞에서 준비한 여과액 10 μl를 비브리오 앵길라룸 균이 도말된 평판배지 위에 점적한 다음 이를 30분 정도 방치하여 건조시켰다. 건조 후 점적한 평판배지를 30℃에서 하루 동안 정치 배양한 다음 여과액이 떨어진 위치에 투명환(Clear zone)이 생성되는가를 조사하였다. 투명환이 생성되는 여과액의 경우가 비브리오 앵길라룸 균을 사멸 시킬 수 있는 박테리오파지가 포함되어 있다고 판단할 수 있다. 이러한 조사를 통하여 비브리오 앵길라룸 균에 대한 사멸능을 가진 박테리오파지를 포함한 여과액을 확보할 수 있었다.
비브리오 앵길라룸 균에 대한 사멸능을 가진 박테리오파지의 존재가 확인된 여과액을 이용하여 순수 박테리오파지 분리를 실시하였다. 순수 박테리오파지 분리에는 통상의 용균반 분석(Plaque assay)을 이용하였다. 이를 자세히 설명하면, 용균반 분석에서 형성된 용균반 하나를 멸균된 팁을 이용하여 회수한 다음 이를 비브리오 앵길라룸 균 배양액에 첨가해 주어 4-5 시간 동안 30℃에서 함께 배양하였다. 배양 후 8,000 rpm에서 20분간 원심분리하여 상등액을 얻었다. 얻어진 상등액에 50분의 1의 부피로 비브리오 앵길라룸 균 배양액을 첨가해 준 다음 다시 30℃에서 4-5 시간 배양해 주었다. 박테리오파지의 수를 증가시키기 위하여 이러한 과정을 최소 5회 이상 실시한 다음 최종적으로 8,000 rpm에서 20분간 원심분리하여 상등액을 얻었다. 얻어진 상등액을 사용하여 다시 용균반 분석을 실시하였다. 통상 순수 박테리오파지의 분리가 상기 과정의 1회만으로는 달성되지 않기 때문에 이때 형성된 용균반을 이용하여 앞 단계를 전체적으로 다시 반복하였다. 이와 같은 과정을 최소 5회 이상 반복 실시하여 순수한 박테리오파지를 포함한 용액을 확보하였다. 통상적으로 순수 박테리오파지의 분리는 형성된 용균반의 크기 및 모양이 모두 유사하게 될 때까지 반복 수행하였다. 그리고 최종적으로는 전자현미경 분석을 통하여 박테리오파지의 순수 분리 여부를 확인하였다. 전자현미경 분석에서 순수 분리가 확인될 때까지 앞에 기술한 과정을 반복하였다. 전자현미경 분석은 통상의 방법에 따라 실시하였다. 이를 간단히 설명하면 다음과 같다. 순수한 박테리오파지를 포함한 용액을 구리 격자(Copper grid)에 묻히고 2% 우라닐 아세테이트(Uranyl acetate)로 역 염색법(Negative staining)과 건조를 수행한 후 투과전자현미경을 통하여 그 형태를 관찰하였다. 순수 분리한 박테리오파지의 전자현미경 사진이 도 1에 제시되어 있다. 형태적 특징으로 판단할 때 신규 확보된 박테리오파지는 시포비리대(Siphoviridae) 박테리오파지에 속함을 확인할 수 있었다.
이런 방식으로 확인된 순수 박테리오파지를 포함한 용액은 다음의 정제 과정을 거쳤다. 순수 박테리오파지를 포함한 용액에 용액 전체 부피의 50분의 1의 부피로 비브리오 앵길라룸 균 배양액을 첨가해 준 다음 다시 4-5 시간 배양하였다. 배양 후 8,000 rpm에서 20분간 원심분리하여 상등액을 얻었다. 충분한 수의 박테리오파지가 포함된 액을 얻기 위해 이러한 과정을 총 5회 반복 수행하였다. 최종 원심분리로 얻어진 상등액을 0.45 μm의 필터를 이용하여 여과한 다음 통상의 폴리에틸렌 글리콜(Polyethylene Glycol; PEG) 침전 과정을 실시하였다. 구체적으로, 여과액 100 ㎖에 10% PEG 8000/0.5 M NaCl이 되게 PEG와 NaCl을 첨가한 다음 4℃에서 2-3시간 동안 정치한 후, 8,000 rpm에서 30분간 원심분리하여 박테리오파지 침전물을 얻었다. 이렇게 얻어진 박테리오파지 침전물을 완충액(Buffer; 10 mM Tris-HCl, 10 mM MgSO4, 0.1% Gelatin, pH 8.0) 5 ㎖로 부유시켰다. 이를 박테리오파지 부유액 또는 박테리오파지 액이라 지칭한다.
상기한 과정을 통하여 정제된 순수 박테리오파지를 확보할 수 있었고, 이 박테리오파지를 박테리오파지 Vib-ANP-1로 명명한 뒤, 2016년 8월 16일자로 한국생명공학연구원 생물자원센터(수탁번호 KCTC 13075BP)에 기탁하였다.
실시예 2: 박테리오파지 Vib-ANP-1의 유전체 분리 및 서열 분석
박테리오파지 Vib-ANP-1의 유전체를 다음과 같이 분리하였다. 유전체 분리에는 실시예 1에서와 같은 방법으로 얻어진 박테리오파지 부유액을 이용하였다. 먼저 부유액에 포함되어 있을 수 있는 비브리오 앵길라룸 균의 DNA와 RNA를 제거하기 위해, 박테리오파지 부유액 10 ㎖에 DNase I과 RNase A를 각각 200 U씩 첨가한 다음 37℃에서 30분간 방치하였다. 30분 방치 후에 DNase I과 RNase A의 활성을 제거하기 위해, 0.5 M 에틸렌디아민테트라아세트산(Ethylenediaminetetraacetic acid; EDTA) 500 μl를 첨가한 다음 다시 10분간 정치시켰다. 그리고 이를 추가로 10분간 65℃에 정치시킨 다음 박테리오파지 외벽을 와해시키기 위해 proteinase K(20 ㎎/㎖) 100 μl를 첨가한 후 37℃에서 20분간 반응시켰다. 그 후 10% 도데실 황산 나트륨염(Sodium dodecyl sulfate; SDS) 500 μl를 첨가한 다음 다시 65℃에서 1시간 동안 반응시켰다. 1 시간 반응 후, 이 반응액에 25:24:1의 구성비를 갖는 페놀(Phenol):클로로포름(Chloroform):이소아밀알코올(Isoamylalcohol)의 혼합액 10 ㎖을 첨가해 준 후 잘 섞어 주었다. 그리고는 이것을 13,000 rpm에서 15분간 원심분리하여 층이 분리되게 한 다음 분리된 층들 중에서 위층을 취하여 여기에 1.5 부피비의 이소프로필 알코올(Isopropyl alcohol)을 첨가한 다음 13,000 rpm에서 10분간 원심분리하여 유전체를 침전시켰다. 침전물을 회수한 후 침전물에 70% 에탄올(Ethanol)을 첨가한 다음 다시 13,000 rpm에서 10분간 원심분리하여 침전물의 세척을 실시하였다. 세척된 침전물을 회수하고 진공 건조 시킨 다음 100 μl의 물을 사용하여 침전물을 녹였다. 상기 과정을 반복하여 박테리오파지 Vib-ANP-1의 유전체를 다량 확보하였다.
이렇게 얻어진 유전체를 이용하여 ㈜마크로젠에서 illumina Mi-Seq 기기를 이용하여 차세대 염기서열 분석(Next generation sequencing analysis)을 수행하여 박테리오파지 Vib-ANP-1의 유전체 서열 정보를 확보하였다. 최종적으로 분석된 박테리오파지 Vib-ANP-1 유전체는 213,970 bp의 크기를 가지며, 전체 유전체 서열은 서열번호 1로 제시되어 있다.
확보된 박테리오파지 Vib-ANP-1의 유전체 서열을 기반으로 Web상의 BLAST를 이용하여 기존에 알려진 박테리오파지 유전체 서열과의 상동성(Similarity)을 조사해 보았다. BLAST 조사 결과, 50% 이상의 상동성을 가진 박테리오파지 서열은 확인할 수 없었다.
이러한 사실에 근거하여 박테리오파지 Vib-ANP-1은 기존에 보고된 바 없는 신규한 박테리오파지라고 판단할 수 있었다. 이러한 사실과 함께 통상적으로 박테리오파지의 종류가 다르면 제공할 수 있는 항균력의 세기 및 항균범위가 다르다는 사실로부터 박테리오파지 Vib-ANP-1은 기존에 보고된 다른 박테리오파지들과는 다른 항균효과를 제공해 줄 수 있다고 판단하였다.
실시예 3: 박테리오파지 Vib-ANP-1의 비브리오 앵길라룸 균에 대한 사멸능 조사
분리된 박테리오파지 Vib-ANP-1의 비브리오 앵길라룸 균에 대한 사멸능을 조사하였다. 사멸능 조사는 실시예 1에서 제시한 점적 실험을 통하여 투명환 생성 여부를 조사하는 방식으로 수행하였다. 사멸능 조사에 사용되어진 비브리오 앵길라룸 균은 본 발명자들에 의해 분리되어 비브리오 앵길라룸 균으로 동정된 것들로 총 17주였다. 박테리오파지 Vib-ANP-1은 실험에 대상이 된 비브리오 앵길라룸 균 17주 중에 총 16주에 대하여 사멸능을 갖고 있었다. 대표적 실험 결과가 도 2에 제시되어 있다. 한편, 박테리오파지 Vib-ANP-1의 에드워드시엘라 타르다(Edwardsiella tarda), 비브리오 파라헤몰리티쿠스(Vibrio parahaemolyticus), 락토코커스 가르비에(Lactococcus garvieae), 스트렙토코커스 파라우베리스(Streptococcus parauberis), 스트렙토코커스 이니에(Streptococcus iniae), 및 에로모나스 살모니시다 (Aeromonas salmonicida)에 대한 사멸능 조사도 별도 실험으로 실시하였는데, 그 결과로 박테리오파지 Vib-ANP-1은 이들 균종들에 대해서는 사멸능을 갖고 있지 않았다.
이상의 결과로 박테리오파지 Vib-ANP-1은 비브리오 앵길라룸 균에 대하여 특이적인 사멸능을 가지며, 다수의 비브리오 앵길라룸 균에 대하여 항균 효과를 발휘할 수 있음을 확인할 수 있었다. 이는 박테리오파지 Vib-ANP-1이 비브리오 앵길라룸 균의 감염 방지 및 처치 목적의 조성물의 유효성분으로 활용 가능함을 의미한다.
실시예 4: 박테리오파지 Vib - ANP -1의 비브리오 앵길라룸 균의 감염 예방에 대한 실험예
9 ㎖의 LB 배지를 담은 하나의 튜브에 1× 108 pfu/㎖ 수준의 박테리오파지 Vib-ANP-1 액 100 μl를 넣어주고, 다른 하나의 9 ㎖의 LB 배지를 담은 튜브에는 동량의 LB 배지만을 추가로 첨가하였다. 그 다음에 각 튜브에 600 nm에서 흡광도가 약 0.5 정도가 되도록 비브리오 앵길라룸 균의 배양액을 넣어 주었다. 비브리오 앵길라룸 균을 첨가한 후 튜브들을 30℃의 배양기에 옮겨 진탕배양하면서 비브리오 앵길라룸 균의 성장 상태를 관찰하였다. 표 1에 제시된 바와 같이, 박테리오파지 Vib-ANP-1 액을 첨가해 준 튜브에서는 비브리오 앵길라룸 균의 성장 억제가 관찰된 반면에 박테리오파지 액을 첨가하지 않은 튜브에서는 비브리오 앵길라룸 균의 성장 억제가 관찰되지 않았다.
비브리오 앵길라룸 균의 성장 억제
구분 OD600 흡광도 값
배양 0분 배양후 60분 배양후 120분
박테리오파지 액 미첨가 0.504 0.987 1.342
박테리오파지 액 첨가 0.504 0.324 0.238
이 결과로부터 본 발명의 박테리오파지 Vib-ANP-1이 비브리오 앵길라룸 균의 성장을 저해할 뿐만 아니라 사멸까지 시키는 능력이 있음을 확인할 수 있었고, 이로부터 박테리오파지 Vib-ANP-1이 비브리오 앵길라룸 균의 감염을 방지하는 목적의 조성물의 유효성분으로 활용될 수 있다고 결론지을 수 있었다.
실시예 5: 박테리오파지 Vib - ANP -1을 이용한 비브리오 앵길라룸 균의 감염 예방 동물실험
넙치를 이용하여 박테리오파지 Vib-ANP-1의 비브리오 앵길라룸 균 감염 예방 효과를 조사하였다. 넙치 치어(체중: 5~7 g, 체장: 8~10 cm) 50마리를 한 그룹으로 하여 총 두 그룹으로 나눈 후 수조에서 분리 사육하면서 14일간 실험을 실시하였다. 수조의 주위환경은 통제하였고, 수조가 있는 실험실의 온도는 일정하게 유지시켰다. 실험 개시일로부터 시험 전기간 동안에 걸쳐 실험군(박테리오파지 투여군)의 넙치들에게는 1× 108 pfu/g의 박테리오파지 Vib-ANP-1을 포함하고 있는 사료를 통상적인 사료 급이 방식에 따라 급이하였다. 반면에 대조군(박테리오파지 미투여군)의 넙치들에게는 박테리오파지 Vib-ANP-1이 포함되지 않은 동일 조성의 사료를 동일한 방식으로 급이하였다. 시험개시일로부터 7일째가 되는 날부터 2일간 1× 108 cfu/g 수준으로 비브리오 앵길라룸 균을 급이하는 사료에 포함시켜 하루 2회씩 급이하여 비브리오 앵길라룸 균 감염을 유도하였다. 시험 개시일로부터 9일째가 되는 날(비브리오 앵길라룸 균 감염 유도 후 2일째)부터는 매일 모든 시험동물들을 대상으로 비브리오병 발생 상태를 조사하였다. 비브리오병 발생 상태 조사는 체색 흑화지수를 측정하는 방식으로 실시하였다. 체색 흑화지수 측정은 통상 사용되는 Dark Coloration(DC) score(정상: 0, 연한 흑화: 1, 진한 흑화: 2)를 측정하는 방식으로 실시하였다. 그 결과는 표 2와 같았다.
체색 흑화지수 측정 결과(평균치)
DC score(mean)
날짜 D9 D10 D11 D12 D13 D14
대조군(박테리오파지 미투여) 0.76 0.80 0.80 0.96 1.12 1.20
실험군(박테리오파지 투여) 0.24 0.08 0.04 0 0 0
이 결과로부터 본 발명의 박테리오파지 Vib-ANP-1이 비브리오 앵길라룸 균의 감염 억제에 매우 효과적이라는 것을 확인할 수 있었다.
실시예 6: 박테리오파지 Vib-ANP-1을 이용한 비브리오 앵길라룸 균의 감염 질환 치료예
비브리오 앵길라룸 균에 의해 비브리오병이 유발된 넙치에서 박테리오파지 Vib-ANP-1의 치료 효과를 조사하였다. 넙치 치어(체중: 5~7 g, 체장: 8~10 cm) 60마리를 한 그룹으로 하여 총 두 그룹으로 나눈 후 수조에서 분리 사육하면서 14일간 실험을 실시하였다. 수조의 주위환경은 통제하였고, 수조가 있는 실험실의 온도는 일정하게 유지시켰다. 실험 개시일로부터 5일째 되는 날부터 3일간 1× 108 cfu/g 수준으로 비브리오 앵길라룸 균이 오염된 사료를 하루 2회씩 통상적인 사료 급이 방식으로 급이하였다. 비브리오 앵길라룸 균이 오염된 사료 급이 마지막 날부터 비브리오병의 임상증상을 보이는 개체가 두 수조 모두에서 확인되었다. 3일간의 비브리오 앵길라룸 균이 오염된 사료 급이 시행 다음날(시험 개시일로부터 8일째가 되는 날)부터 실험군(박테리오파지 투여군)의 넙치들에게는 박테리오파지 Vib-ANP-1을 포함(1× 108 pfu/g)하고 있는 사료를 통상적인 사료 급이 방식에 따라 급이하였다. 반면에 대조군(박테리오파지 미투여군)의 넙치들에게는 박테리오파지 Vib-ANP-1이 포함되지 않은 동일 조성의 사료를 동일한 방식으로 급이하였다. 비브리오 앵길라룸 균의 강제감염 후부터 3일째가 되는 날(시험 개시 8일째)부터는 매일 모든 시험동물들을 대상으로 비브리오병 발생 상태를 조사하였다. 비브리오 앵길라룸 균에 의해 유발되는 비브리오병 발생 상태 조사는 실시예 5에서와 같이 체색 흑화지수를 측정하는 방식으로 실시하였다. 그 결과는 표 3과 같았다.
체색 흑화지수 측정 결과(평균치)
DC score(mean)
날짜 D8 D9 D10 D11 D12 D13 D14
대조군(박테리오파지 미투여) 0.87 0.97 1.00 1.13 1.20 1.23 1.33
실험군(박테리오파지 투여) 0.90 0.80 0.77 0.70 0.43 0.20 0.13
이 결과로부터 본 발명의 박테리오파지 Vib-ANP-1이 비브리오 앵길라룸 균을 원인으로 하는 감염 질환의 치료에도 매우 효과적이라는 것을 확인할 수 있었다.
실시예 7: 사료첨가제 및 사료의 제조
박테리오파지 Vib-ANP-1 액을 이용하여 사료첨가제 1 g 당 1× 108 pfu의 박테리오파지 Vib-ANP-1이 포함되도록 사료첨가제를 제조하였다. 사료첨가제의 제조 방법은 박테리오파지 액에 말토덱스트린을 첨가(50%, w/v)한 다음에 동결건조시켜 제조하였다. 최종적으로 고운 가루 형태로 분쇄하였다. 상기 제조 과정 중의 건조 과정에는 감압 건조, 가온 건조, 상온 건조도 대체 가능하다. 대조 실험을 위해, 박테리오파지가 포함되지 않은 사료첨가제도 박테리오파지 액 대신에 박테리오파지 액의 제조 시에 사용한 완충액(Buffer; 10 mM Tris-HCl, 10 mM MgSO4, 0.1% Gelatin, pH 8.0)을 사용하는 방식으로 제조하였다.
이렇게 제조된 2종의 사료첨가제 각각을 중량비로 250배의 양어용 생사료와 혼합하여 최종 2종의 사료를 제조하였다.
실시예 8: 약욕제의 제조
약욕제는 다음과 같이 제조하였다. 박테리오파지 Vib-ANP-1 액을 이용하여 약욕제 1 ㎖ 당 1× 108 pfu의 박테리오파지 Vib-ANP-1이 포함되도록 약욕제를 제조하였다. 약욕제의 제조 방법은 박테리오파지 액 제조 시에 사용하는 완충액 1 ㎖ 당 1× 108 pfu의 박테리오파지 Vib-ANP-1이 포함되도록 상기 박테리오파지 Vib-ANP-1 액을 첨가하여 잘 혼합해 주는 방식으로 제조하였다. 대조 실험을 위해, 박테리오파지가 포함되지 않은 약욕제로는 박테리오파지 액의 제조 시에 사용한 완충액 자체를 그대로 사용하였다.
이렇게 제조된 2종의 약욕제는 부피비로 1,000배의 물로 희석하여 최종적인 약욕제로 사용하였다.
실시예 9: 넙치 사육에서의 사양 효과 확인
실시예 7 및 실시예 8에서 제조한 사료와 약욕제를 이용하여 넙치 사육 시의 사양 결과 개선 여부에 대하여 조사해 보았다. 특히 본 조사는 폐사율 관점에서 실시되었다. 총 1,000 마리의 넙치 치어를 500 마리씩 한 그룹으로 총 2개 그룹(사료로 급이한 그룹-A; 약욕제로 처치한 그룹-B)으로 나누어 4주간 시험을 실시하였다. 각 그룹은 다시 250마리씩으로 구성되는 소그룹으로 나누어지며 각 소그룹은 박테리오파지 Vib-ANP-1이 적용된 소그룹(소그룹-①) 및 박테리오파지가 적용되지 않은 소그룹(소그룹-②)으로 나누었다. 본 시험에 대상이 된 넙치는 치어(체중: 5~7 g, 체장: 8~10 cm)였으며, 각 시험 소그룹의 넙치 치어는 일정 간격을 두고 위치한 격리된 각각의 수조에서 사육되었다. 각 소그룹은 다음의 표 4와 같이 구분되고 지칭되었다.
넙치 사양 시험에서의 소그룹 구분 및 표시
적용 소그룹 구분 및 표시
박테리오파지
Vib-ANP-1 적용		 박테리오파지가
적용되지 않음
사료로 급이한 그룹 A-① A-②
약욕제로 처치한 그룹 B-① B-②
사료 급이의 경우에는 실시예 7에서 제조한 사료를 표 4의 구분에 따라 통상적인 사료 급이 방식을 따라 급이하였으며, 약욕제 처치의 경우에는 실시예 8에서 설명한 약욕제 제조 방식에 따라 제조한 약욕제를 표 4의 구분에 따라 통상적인 약욕제 처치 방식에 따라 처치하였다. 그 결과는 표 5와 같았다.
넙치 사양 시험에서의 폐사율
그룹 폐사개체수/시험개체수 폐사율(%)
A-① 8/250 3.2
A-② 43/250 17.2
B-① 10/250 4.0
B-② 55/250 22.0
이상의 결과로 본 발명에 따라 제조된 사료의 급이 및 약욕제의 처치가 넙치 사육에서의 사양 결과 개선에 효과가 있음을 확인할 수 있었다. 이로부터 본 발명의 조성물의 적용이 동물의 사양 결과 개선에 효과적이라는 결론을 내릴 수 있었다.
이상으로 본 발명의 특정한 부분을 상세히 기술하였는바, 당업계의 통상의 지식을 가진 자에게 있어서 이러한 구체적인 기술은 단지 바람직한 구현 예일 뿐이며, 이에 본 발명의 범위가 제한되는 것이 아닌 점은 명백하다. 따라서 본 발명의 실질적인 범위는 첨부된 청구항과 그의 등가물에 의하여 정의된다고 할 것이다.
기탁기관명 : 한국생명공학연구원
수탁번호 : KCTC13075BP
수탁일자 : 20160816
SEQUENCE LISTING <110> iNtRON Biotechnology, Co. Ltd. <120> Novel Vibrio anguillarum bacteriophage Vib-ANP-1 and its use for preventing proliferation of Vibrio anguillarum <130> KP090476 <160> 1 <170> PatentIn version 3.2 <210> 1 <211> 213970 <212> DNA <213> Bacteriophage Vib-ANP-1 <400> 1 atctgaatat tcatgtctgt gattcttgca atggcagaac gtatactaac tatagcctcg 60 tctgcctctt gtgctttgtt aaccgcttcg attgcagtgt tcttactatc attcatcacc 120 acggaaacag aatgtgcgcc tgattgtaac tgttcgatca tctgcttgat ttcagtagtt 180 gactcttgtg ttcgtttagc aagagttcgc acctcatcag caacaacagc aaaaccacgt 240 ccctgttcac ctgctctagc tgcctcaatg gcggcattaa gtgccagtag gttggtctgg 300 tcagctatct catttatcac ctgaagaact ttttcaatat tgtcagaagc tatagcaaga 360 gattgaactt cttgcacggc ctcatcaatt cgactagcca acacactaat ggtttgggtt 420 gtatgattaa ccaccacatt accatgatta gctgcatcat cagcctcttg agcagccgca 480 gctgcatttt gtgcattggt tgcaacctca gatgacgctg tggccatttc attcatagcc 540 gtggccaact gctccaattc ttctaattgc tttgtcatag ccattgcgga gtttctagca 600 ccagcatcgg attgacttgc acctatttct atctgtccac taatgtcttt tagatggata 660 attaactctt ggagtctctg tgtaaaggtg ttaaagttgt tagcaaggtg tgagaattcc 720 aaatcggtgt tagtgtctaa cctttgagtt aaatcacctt cgcccgaagc aacattctca 780 attgccttgt ttagtaaacc aagtggtttc atcaagaacc cagttaggaa catcataata 840 gggaaactta cgatgatagc aacaatcgaa taaaccaaag acagattccg catattagta 900 acgtcagaaa atgctttttc ttgatttatt gccgaaccaa caaaccaccc attctctttt 960 gtcttagaca aaccaataac gtactcttca ccgccgatgc ttagattctg taatccctct 1020 ctgattttta aacccggtat ggtttcagtt attacgctac cgtttagctt tttattaggg 1080 tgtgcaataa caacaccgtc actggatact ataaagagga aaccaatttt atctaacgag 1140 gtgcctgtga ccagacccgc taattcctca aggctaacat cgtaaaacat agcaccttgg 1200 aagcggctgc cttcgcgtat aggggttgcc acagatacaa taacttcccc tgttgcagaa 1260 tcgacataag gagcagtagt cactgtttta tttttgctct tggcgtctat gtaccacggc 1320 cttgctctcg catcccaatc tttacctggg tgccagctag gctcattaga aataggatta 1380 ccgtcttttt caaaaccacc gccaacaata agaaacattt ctttcaacgt tggcttgtta 1440 atcacttcgg tgatgttctc taatgacgga ttgctgttga ttaaatcact tgagtattta 1500 accaaagcta tttttttatc gatgttatca tcgacagatg ttcttacggc attgactgtc 1560 tcaccaacgt atgtgtcgac attagtttta acaatccctt caacagtttt atactgttgg 1620 aatgacaata acccgacggt tatcatcaga agcgcagacg cccctgccgt tactttatga 1680 ctgaatttca tttttaatcc tcttctgaat taagattaca aaaaaagagg gggatgtctc 1740 cccctcaatt taattacgtt gttagacgcg tttgttgtat taggctgtaa gccatcacaa 1800 tatcctcgaa gggatactta ctaagttcac caactaaacg attgacgttt tccgtaacct 1860 caaacagctc tcggtcatct tcaataccat acagcgattt aattcttcgg agtgttttct 1920 ttcccgggaa tcgttttcca ttctctatgg tggagtaata agctggctct atgtctaggg 1980 ctttagcggt atcgcttgtg cttctattac tcaataaccg taaggttttt attttagttg 2040 caaatattac tccactttcc acattttgtc cttcagggcc atgacgtact cgttgtagtg 2100 aggttgcagt gccccataaa gagaacgtaa tgtgtctgga tcggaaattc cgcagttaag 2160 cacattacta aacaacggag tgtctttatt gtacaaatct cttgaacgct ccatgagtag 2220 agcgatgtga tgaggatgtc ctttaccacg accacctgtt cccaaatcga agaattgaac 2280 cgagttgttc aaggcaccgg agatcacttt attgacgtca gggtaaagtc cttctagcat 2340 caaacgatgt aagttacgac caaagattga aagaatggtg tttgtttcca ggtactctga 2400 gtagtacggt actgaacgct ccagagttag aaatacttca cgcccaagga aactattact 2460 tggtgaactt gaccatgtgt tgctcagctt actaccacgt gacaactcaa catcatactc 2520 gtgttggtta ggaatctgat ttaacatcat gccatgttca ggatagtacg ctgtgtcgaa 2580 aaccggaagg tggtgcactt tgttgcctgt atacaaaacc acaggtttgt agttactatt 2640 ctcaatgaaa ccaaacaagt aattgtcctg tccgttgcgt tggtactcca tgacgaacaa 2700 atccaacttc gcttcggttg tctcgccttt gatacccacc aagtcacgta gctcaacctg 2760 atcaatagac aactcgccac ttgccaatcg ctccaaggtg cgttgattca attcttgtgt 2820 gaattgggta ttgatgaata ctaggttgtc gcgtttcacg tagatgttga aattttccat 2880 ttttgttctc tcttttccga tcgttatttt taacggtgca agtatatatt ttgacactct 2940 agatactaga ggggtagggg ttatatagat caagatatga atcgatcgag gaacgtagtt 3000 tacactacaa gtacttaatc gattcataac atttattttt gtttcatacc aaggttatct 3060 atcaaaagat tttccaaagc atatgctgga tgagcaagac tacgacgtcg tagctgagta 3120 ggtggcttac aacccacgta taagtcttgg gagaaaccat caaaaggaag tagtcccatt 3180 aattcttctt taatgaaagc aaatgtctcc aaagatttct cttctagctc aatagcatca 3240 ggaacattac cgatgaccat atcgttgtat tccgaaacca gttcttcgaa gttagcggag 3300 ttatcggcat aaatccaata ataagctgat agaagaaatg aagccatgcg acggtccact 3360 ttaccgaatg tttctaagtc gtgttcatgg atagcacgga ttgcttcgga tatagttgac 3420 ttgatgtcgt ctaaaccttt gtggaataaa ctaaccttat agtcctctcc ttccagacac 3480 cagcgcattt cagtcaacct tgcccataca cgattatgga acgataggaa agccaaacgc 3540 tgacccggcg agatttcctt ttgaaggaac tcttccttaa tagcgtagat aggatcgatt 3600 tgaattcgtt gctctttgat aagcgattcc aagaatttcc aatcaccctc ttctagtgaa 3660 cgattggcag tgttctctgc aacacgctta tagtgtttgg ccgacacaac acgaaccttg 3720 tcaacgtagg tcatcaattt ctgtttacct tcctcactct caaatgagaa ttctggaaca 3780 gtttgattat cgtggttgtc gatagccgaa tgtgtaacca tgtagtgctt accctcgact 3840 tctttagtaa cgaacttgaa ctcgcttctc atacacacta gcgaaggcca atgactagac 3900 ttcagataat ccgccataag gacgatgtgt tctttgaaca cgtaacccca agccaggctg 3960 ctaacattac cagcattagt aatgtgtgtg atttccccaa attttgaatt taggatagtg 4020 gtgagtgctt gtgccgatga tgttgctcct agcgcatcga ccattttaga gaaagccgca 4080 atgccatcgc cacgattcga gttgttaaca aaacgaggtg ggtaatcgag tttaccattt 4140 aaaggtaaaa ccaagattaa cagatcacaa tggtctgtat cgaagttatt ggttcgaata 4200 ccaataactt tgttttgata gtccccacct tcaagaaaat catgaaagtc tgccagctta 4260 atgtgtttat ccacgcgcat tttaaatttc ctttaaacta tgattccaag tatcttcagt 4320 gaaaataaca ccgagacgaa atggtacttc gctcgcacat agacgattag ccttaatcca 4380 atcgttcaat ggtggcgctt tatgtaatgg gtgatttggt tcacttaaga ttacttgtct 4440 agtcgagcca cttctagtaa ccttacgatt aacagtcatt ttaaatctgt gtggtgattg 4500 gtaattgtct tcgacataga cgaggttatc ctcgcctaat tcaatcatca aatcatccag 4560 attatcaatc tctggttcaa ccacatctga atacaccaag aacctcccct ccttaatgga 4620 ggagacttct tcgacataca taactttacc catctcacac ctcaggtact tcgtatatct 4680 cgttgtcggc ttttagagtg aagtcagtat gctcttcggt gctgatacct agctccaaac 4740 ctacagtgac ttcgttattg tcgtattcga attcaatacg tgtaatgtcg tcgatatcca 4800 tgatcgattc tttacctgtg attaattcaa atttaacagt gtcgatgtgg tagttgcaaa 4860 gttcttttga aatccccacc atctcttctt tcttcggtgc acgaaaggtt agatggtata 4920 aattattttc tatctgtttg atggaatagg ggatcaaacg tgtttctttt ggaaactgat 4980 agatgaccaa agttttgaaa taacttagtg aaggaacgta accgttttga acttcaatga 5040 ataaatggta gttgttcggg tagatcatcg aaaacactcc ttcttaattt caattttata 5100 ccaagccaat agataagctt caatggttga acgacactct acacagcaga gagccttctg 5160 accctgacgt aaccaatacg tttgcacagg tggtctgtag acgtacgtgt ttgtacctag 5220 ctcaatgttg ttatcgacac accatgccaa gatatccttt agtgacacta tatgtccgtc 5280 aggaatggtg accattggtt tagtcccatc ggatgcttgg ccactatctg cccaggcaaa 5340 tactgcctct gggataggac cacggtcatc ccaatccaat cgatgaaaaa gtttttgatt 5400 accagtacca gtccatatat ttaacatttt taaaattcct ctcatttaac ctaaaaaata 5460 agagaggtca ctacaacctc tctaacgcat caattaatta cagtagccgt tcttgttagc 5520 gtatccgtag ataagcgctt caacaacact accgtattca actgctgata gttcatcacc 5580 gatggctgca acgaaacgtt cttctttcac gccaccttct tcagtagcag taaccttggc 5640 actacccagt ggatagtctg ggttatctac tgggtcttta acacgcactg cacgaatgtt 5700 gttatcgtga cagaattgca acacacctgc aaatggttca acatcacctt tacgtacacc 5760 ttcgtccacg tcaccgttgg taatcatcat caacgaaggt aacgcgttat cgatcgtacg 5820 aattaggttt tgactgatga ctttatcttc ttcaagaact aagtcgatga tacggaaacc 5880 gtctgttgtt aattgaacta cttgatacat tttaattacc tttaactact tttgttgaaa 5940 gattagtcac aaagaccagt ttgattagcc caaccgtaaa tcagggcttc gatcgctgtt 6000 tcgtattcga catcggaagt gtcgttgccg atagcagcaa cgtaacgttc ttcttcttgc 6060 gtgtagacgg taacgctatt gtcaagtgcg ccctgctcca tgaaagacac aatgccgtta 6120 tccaccaact tgatactgac cggacggatt tcattggcat tacagtaacc gagaacttgc 6180 tttagaggaa ccttggaatt ttcagattcg ccggatgggt caactaccac cataaggccc 6240 ggataagcta agtcaagctt ctcaataaag ttagcggtgg ggacaagacc ctcgctaacg 6300 accaaacgaa cattgcgtgt tgttccattt acttcttgaa ttactgggta catagtagaa 6360 tcctcttaag gataaaagta gaaaaagtgg caaggtttcc cctgccacgg ttgataggtt 6420 agttaactaa gccgtcttta cgctgcttaa ttgcaatcat aacctgagta gttagcatca 6480 tggtggctac agatgccgca tattccaaag aaccacgtgt cacttttact gggtcaatga 6540 tacccaattc aatcatgtca tcgtactcct cggtacgtgc atcaaagccg tacgagctat 6600 cgttatttga aagaacgttc atgataacaa cgtctggtgc taccgctgcg ttctcagcga 6660 tttgtcgaat aggtgcttcc atcgctttaa tagcgatatc catacctaaa cgttcactgg 6720 ttgttacatt aacagaagcg aacatatctt ttagtttctt agatagacgc agtagtgtta 6780 caccaccacc tggtacataa ccttcttcca gagcagcacg tgttgcacca acggcgtcgt 6840 ccgcacggtc tttacgctct agcatttcaa tttcactaga ggcactaact tggataactg 6900 caattgctga atttaacttg gccaatcgct cagtcagatt cttcttagca aagtcagtga 6960 tggctggttc ttgcagtttc ttgcggatac catcagcacg cgcttcaatt tctttacgat 7020 cgcccttacc gccgaggatg acagtttctt tactgctaac acgaacttcg tccgcagcgc 7080 cgagaatacc atccatacca gactgttcaa agtcatagcc tgcatcgact actttagcat 7140 tgaccaattt agccaagtcc tgaatcaact cacggcgttt atcaccaaag ctagggctac 7200 gtacagggat agttgacttg tgacgacggt aattgtttaa gaagacttct gtagcatact 7260 ggtcgaagtc atcggccaga atcagaagtt tgctattctt gttctgtgcc agctccagaa 7320 gcggtacgta cttgtcaaag ttggtttcat tgatatcgcc actgacaatc aagacaaaga 7380 cttctttggc aactacggta tcttcgccat ccattaagaa gaatggtgag atgtacccgc 7440 ggctaatggt cacaccatca acaaaacgaa tgtcatcgtc gtaacctgtg gcttctttga 7500 tgtcaacaac accttcgatt cccacacgat ccatcgcttc tgtgataagg ttagctaaac 7560 cttcatcacc attggccgaa atcatcgcaa tgcttctgat gtcgtctttt gttttacatt 7620 cgatggccat ggacttaagt tgtagaatgg ctgcttccac aatacggtca ataccacgtt 7680 tcacctctaa aggattagaa ccgttgttaa cagctttaac accttcattg attaaagcat 7740 gtgcaagcac tgtcgcggta gtagtaccgt caccagcaga gtcacatgca cgaacagccg 7800 cttctttaac catttgcgca cccatatcct ggaatgggtc ttctaagaat acactacggg 7860 ctacagagac accgtcttta gtgatgtgtg gtgaaccagc tagtttctga attacgacat 7920 ttcgaccttt agggcctaag gttgagcgaa ccgcatccgc cagaatattt acacccttaa 7980 ccatttcatc gcgtgcgttc ttgtcaaaga ttagttcgcg tggagtttgt ttagccatgt 8040 ttgaaaattc cttagtatta cttgtttgaa atatggattg ttacggggtg gattttattt 8100 tgattgttta acgattttgt ttaggtactc gaaccattgc gggtggtact tttcaccgtc 8160 tacatcgtta ggcgtcactt tatctttacc aagtacaccg tcaaaagtgt gtaggtaaat 8220 tgtgttttct ttacgcgctt cgccgactgt gtagctacgg cttgtgctgc tgttaaacgt 8280 tagtttgttg tagaagctcc gcagtttgac cactggtttc caaacctcac cttcttctaa 8340 atcactcggt ggtgttgtgg tatatgtgtg ttcaggaaac tcttctttca gagctttgct 8400 aattgcctta acgacatcaa cagtgcattc cttgatctct tcgccattcg ctgcgtcagt 8460 gacgtgaata agatgaacct caaaagagtc atcattacac accacaacat gtggtgagtt 8520 tggatttagt ttagatgtct tttcaaattc aacatgaatc tcgacattca ttgcactaag 8580 tgcgatatca gcaaatttac ccatttttaa aattcctcaa aagtaataaa gagaacccta 8640 gcgcctctca tactagggct actagggtta tttttcaagt tgtattaaga aactgttaca 8700 ttgatttcgt aacagtcaat taaagtagtt aacccatctt tacgataagt tacctcgata 8760 gtgcgttcat cgaactggtc tgagatatgg aaatctaatt cgcggattaa atctcctaag 8820 tcttcgtctt ctacaacact attttctttg tttaacttac cagtgttgtt gctagagata 8880 ctagctgtga tagtttcccc tttagaagtg atgtatttaa tctcttctgg atgatcgaag 8940 gctgaggctt ctttaatagc ttgtgctacc aattcagcct ctgtatttat cacatcgatg 9000 tagattttga tgagaggcaa cgacacaaca atattacctt cgttgtcata aacacctgtg 9060 tcgtaactct caccagaatt caaaacagac tctaacgatt ccaaaaactg ataagcagtt 9120 ggattcagtt tatcagacgc catcatatcc atcatggccg aatggtcttg tgtatccttg 9180 aatccaaccg tgtccgcatt tgggactatt ccaattagta ggttaccgta gttgaatgtt 9240 tgacgtaacc cagggttggt tttgagagaa tggattgctt cagcagcgga taacaattct 9300 tcaatttgtt cagggtagat catgttttaa aattcctcat tggtctaagt acacaaagat 9360 aacatatacc taattatttt tagtatcggc cgcaagttta gcagccaact ctatatcgaa 9420 tccaccagag gaaacctcgg tgcgattcgc tacaacgtta tcttcatcaa agacacagtt 9480 atttgcctcg actaataacg cagcccttat gttagagatt gacaacttta agatgtctag 9540 ggaattaggc ccatggggga tagataaaga tactggggtg tttatagaca caaggtcttc 9600 atcaacctca ccttcaccaa tgctttgttt aagtccagct aaggcattct tttcaagacg 9660 ctcaatcacc gaggtgactt ccgattccac ctcttcgcga gacataccac gtcttaagtt 9720 aagtgccaag ttccctttta attcgtaact tttcatctgt catttctcca ttgagtatat 9780 caaataagga aagtatggtt aaacccttag ggatggttaa cccaccaatt attacttcgt 9840 caccaaccac aagaacattt aaatggtcct gaaaagactc cacttctcca cgttcagggt 9900 taccgtatag tttaatgtaa gtggctatgg ttaaagccaa tgaaatattc tttggattta 9960 gagaactgtg gtctatcggc gcaccgtcct taaaacattt tagattccat atggccgtct 10020 ctaaatcata gtccctgggc tctggctcag ttgtttcttc accacaccat tggtttacct 10080 ttttagccac catggcataa tgggccacca gtgatttaga agggtcttta tagaaggaaa 10140 agaactgggt gagtaaatca cccagtgagg tagttatgta aggtcttgtc atcatccaac 10200 ctttcgccaa atatgttcct tgaattcgcc attgacaatc gacttggcca agtcaacgtc 10260 catcttagca cgagtcttta tcccactaag ttcacaagct aatagcggac gtccagcttc 10320 gaaaccagtt gtgttgtaaa tacgatttag ataatcgtta acaatctgag tggttaaccg 10380 aggaagctcg attgtgtggt ccgttctacc atccctgaag atagcaccat ccatacgttc 10440 gatgtggttg gtcgtcatga atacaagaac atcatctaaa ggtgacacac catcaagaac 10500 atttaagaaa ccttgcaagt cgaccgatag accatccaac aaagaactgg tagagacccc 10560 agtgtttttc tctgcctctt tatccttatc tgacttctca acgttgagtt tgtgagtacc 10620 gccacgattt gccgtcgcag ctaaaccatc acagtcttcg aataatagga tgctacgtgg 10680 tggcatttgc gcaataccat taatcaaccc attagtggaa accatcttta agtcgatggt 10740 gcaaatgtta aacttaaact ccgaggcaag tgctctgatg atagaggttt tgccagtacc 10800 gggctcccca tgaagcataa aggttatctt ccacgctaga cccatgtcgt agtatctgtc 10860 tctgttatcc agatagaact gtatctcact acggaagaac tgtttgatgt cttcgctaag 10920 agctagagag tctaaaccac ctgctttaat aacactctgt ttcttccacc catcacttgt 10980 taggttaaag aaacgaatgc catcttcgtc ctcatcaggt ttaacatgtt caatcaaagc 11040 ctgcaaagct ttaggtgacc gccctagtgt gtagacaatg atttcttctg caacgtcagc 11100 agtattgcct tctaatcggt tctttcttgc catgtataga acaagaccac gtctgaataa 11160 atgccaacct aatcctaagc cataacgatg ttctcgtagg ccatccagta gattaccccg 11220 gtctttccaa tctgacacaa gagataggct acgtgagaaa ttacctatac ggttttcata 11280 gatgaaatta ctcaggttgt tgtaaacatc acgagacgca tactgatgtg tacccaattg 11340 aaaactagtt acacattgct ctctgaaaaa cctcgctatt tttgcagggg ccttccatag 11400 aacaaaacca accgcaccag acagtgcaac agtgaccgaa cccatcaagg cagctgcaag 11460 tagctggtta ccatttgata ccgattcgat gtagtgaatt aaatcagtta taaagttact 11520 gatgaacaca ggcaatcccc tttcttattt tgtaccaacg atgacaccag tccatgagaa 11580 gtcattagcc tgactaatcg tgttggtggt gatttcttta caggtaggtg gtacgtgttt 11640 gaaatgacga ctgtgttggt agaaccattt gattgacaca atgtgtgtgt cagtgatgta 11700 ggccaatctg atattggaaa tgtttttatc agggttaatc acactacgta aaaggtcagt 11760 tacttcttta gctaaagcaa atgaactttt ttctttttcg tcaccagaga taatctggtc 11820 cagtttgttg ataatttcat tagtgtcttt accttcaggt aattcgaact ctactgctgg 11880 cggggtcaac acagtgtcag tttgtgtagt cacgttaagg taaaaagatt tttggtcaga 11940 cattttgata ttcctctgat aaataatgta ggttgtaatg cataataatt ttcagaggcg 12000 ttaaaaaata aagagagagg ccgaagcctc tctattcgaa acaaccatag agttttaaga 12060 acatactcat ctctaaagcc caaggtgttc cagcaggttt atcatcagta tcaaatgtgt 12120 ttttaaaatg cacaaattga atttgacaat taagagcata ccagctaaac cctgtgatga 12180 taaattcacg acaggtccga taggtataaa ctttatcacc ttcttttagt gtttcaggat 12240 ttatgggttg taggttttct tttaacaaca tggtggtccg ccgtgggaga aattctcaac 12300 atgtagctgt gccatagtca cggcttctgt aaaggagacc gggcctttaa atgccacctg 12360 accactacat acagcagatg aacctgcacc acccatagag acattaccca atagaccaat 12420 agtaggagct ttgatagtgg cactattacc ctctactgtc catgtttgcg ctttggcagt 12480 gtaggtcgaa gtgtcaatag cgtagctagt cgccttggct ttataggttt tggtgtttat 12540 gtcgaaggtg tcacattcaa aaccaataaa tttagatttg aacttaatgg tgtctttagc 12600 gtacccgtag atattcgttt tattcatcac aaaggtagtt tctttcgcgt tcttccaccc 12660 gatattggtc tcagcagaat caaaccatcc actattacct atatcatccg aaatcacaaa 12720 acgtccatct ccagtattca gctgtatgct ataacgacaa tactcaccat ttgatttact 12780 ggtgttaaga gtgatatgct tatcatgaga actaatcatt aagtaataag cattactaag 12840 gtcatctttt aaaccattga ctgggtccgc actaaaagcg tagactacgg tttcaaggcg 12900 tttaacgtta gagacattac ggtcctgcca gaaaaacatg tcagtctcac ccaagcgcca 12960 aatcaaaact aaatctttaa ctttgacatc tgggggagtg atgcgatttg tgttaaaatc 13020 tatccattga gcagggatag agttacctgt ccgcatagtg acaaagtctt taccttccgc 13080 aatattgtgc tcgactttct ctacgtttaa tccagcctca atcgactctg cttgtgagaa 13140 cctgacctcg actggataaa cttgtatctt gttttcacct cgacctttgt ctttcgcaac 13200 taacccataa ctataaaaag ttaattgtga agttggtcct atcattcatc cccctcgtag 13260 atgaaattct taaacccttc gaattgaaca aggctcagat gtggtttgcg tttacgatga 13320 gtcaatccac gattgttatc gttaaatggc ttaaaggaag tatcccaaag acccttgact 13380 cgctgatagt ccgttgtaga caaatcgttc ttgtaacgat gtccgagata agtcaacgtt 13440 ccttctttat catttaactg attatcagcc gacatgaata aaaatgggat aagttgcccg 13500 tcggagtcaa tcagcatctc accgtgaaaa tccaagaact ccgtgaggag ataaccatcg 13560 ctgttaatct cattattgac aggggtaaag tgggctgtta aatcaccacg gtaaggtaca 13620 acaaacgacg ttgggtgatt aagcaactcg gctagagtga tagactcaaa ctcgaaatca 13680 atacagaatt gggtcagatg agcagtggtt ataaataact tctctgctgg aatcttcaac 13740 gattctgttg tgaagacaac atcgttatca ttcttcatat cgagtacagg tttaccgcct 13800 atgaacaaca acatgccaga gtatcctgct tttggatact taatggataa ctcaccctcc 13860 agtgtgacga taaccagctg acttaactgc acaggtaagt cacagtctaa ttctgacata 13920 tccaaagcag ataactgaat accctctttc acaccaccat tgtaaacagc agcatatggg 13980 agatagtagt tgtagtccat tttataactg tagtagaagt acggtccgat agcccagatt 14040 aggttagggt tatcgtactt gtcgcgatta agcaacaaaa tatcggtagc ttcttcttct 14100 aatattggct gactagggtg aacaccaggt ttcacaccac gtgcttcgaa agcgtcatgg 14160 atgtaattga cgtatctcga caagccacta ttgataccag taatcatagg ctttaaaacg 14220 aagacttcgt ttttaattaa cccaaagacc tcttctaatg taagagagga atcaatagcc 14280 accaagtttc tagagagatg atcaaagagc tcaatagagc ctttatcccc atcccaatcg 14340 ataacaggca aatgaatttg acgataatca tttcttaagt ccccgtagga tttagttaac 14400 aattccgcca ctgacgtaga tgtgaaacgt tgggagtgaa tccattcgcc acttcttttc 14460 tctaaatagg ctataccttc gttatagatg gtaatcactt ccgattcctc cgatttatat 14520 gataaattga atcctttaaa ctgcctctaa ggtgacacaa atgatagaat ttgaccccca 14580 taaaactgaa gacagtaata agttttctgc cactggtgtc tcagttggcg gagagttgtc 14640 tagagtgttt cttatcccag aggcaccttt ctattcagac ggttgcgtag taaagaataa 14700 cggaactcaa atcttcgaag gtaaagactt tgcatttgtc ctaccctttg ccgagatgac 14760 acacaaaacg gcccgccgcg tattcggcgg tatctttctt tttggtaatg gtggcgctaa 14820 tgtcacttta gatagtcatg ctatcggttc acgttaccag ttagaaccac agagcgtcat 14880 tagtcaattg aatactaaga ctctctctga acttctaaaa acctcctggg aggatatttc 14940 tggcaatccg tacgttccgc ttgtgaatgt gcaattccaa actgatacgt ggttcggtga 15000 agaagaatta gcggcacagc tgaaagcatt agaaaatgca atcgtatctt cagatgttac 15060 agaagaagtc cactatatgt taattaataa ctggctgact cttctagaag catacgtcga 15120 caacccagaa ctaattcaac atctgcaaga aacgggtaac gtgcataacc acactcctga 15180 agaactaggg gctcgtcgta taaatactaa tgcggcagac acaacccgtc tgttcgggcg 15240 tgataaagaa accatgcttg cagatttact gcgcgattta cccaaggtgt ccgacttagc 15300 aaacaatctc cgtaaaactg gtgggctagt cgataacatg acgttgtccg aagcgtttag 15360 tttgatagca aatggtcatt ttgttatcga taattacgac ggtcgtttca gctctacttc 15420 ggatgctaaa caaaccatca ccgcaccaca aagcattaat tttaatgttg gtggtcatat 15480 ccttacacta gacggtctta actccaagat tctccttgat ggtaaagaac tcatcactgg 15540 tgaaaacgtt gaccgtgagg cggctaacaa cgccacaatt gaagcggata ttaaaactga 15600 aaataccgca tcagttactt ggactggtaa cggctctact gacacaccgc taaaaccatc 15660 attgtctaaa gagacctttg acggtaacgg tatcgatgta attactaatc agcctacaca 15720 aggtctgtta aaggcagcat cgcctgctgc ggcaaaagtc ctaacagacg aattggcaaa 15780 gaaggccatc aaaggtaaca ccatcgcagg aaaggctttc aatggtaatg tcacactaac 15840 taaagctgat tttcgtggtg ttgagagtgt gcaagattac tccgatgaag acatgccgtt 15900 gtctgatgct gcaaaggaag ctttctctaa gaaggctgtc agtggccacc gccatgacat 15960 ggaggatttc aatatccaac atgcttctga aaacgaaatg ggtatctttc gatactctga 16020 caatgaagca atgatggtag aggaagtaag agactggttt gaagaactga catcttattc 16080 aaataagaca gatgggatga ttgaaagaga agccatcaat gtcttaagct ttggtgaggg 16140 gcaaggggaa tcggtagaag gaattgttaa aaacggtttt cgcatcacca tccctgcgaa 16200 cgagtatgtg gaaaatggca ttgcgattat gatcccacta aggactattg actttgccac 16260 ggtgagtgat tataaaaatc gttacttcta cgtatctgtc gattctagtg gatacagttt 16320 ctctaaaaca ttagaagatt cgaagtttgt aattggttgg gtgtataccg atagtactgg 16380 tgtgctgtca gttgatattc gtcaagtaac taaactcatt gattctaaaa ccaacgacac 16440 acacatccgt gccgttgtcg acgcccatgc taatcgtgtg tttgacaaaa ccttccttgg 16500 tttggacaat gttgaagatt atccaatggt taatgaccca acgtcggaat cacagggtta 16560 tgcgacaacc ttctcagttg ctgcattgtt ctgccgccat aacacgttct ttaaaaagcg 16620 tggtgtattg acaccagagt tgcgaacagc atctgaaaat ggagtctttt tacaatctct 16680 tcctccattc cttgtcagac aaatgccaca gaaagaccct agtgaaattc cattagagaa 16740 ccaaacatac actttcacta atgacggtgg ttacattgtt tatggttcaa tgccacaaga 16800 tggctatgtg gatgattcaa atcccaacac accaaaccca acgtacccta tcggttctag 16860 atactacact gaacaggact tcaaccctag tagttatctg ggtggtgttt gggagaaggt 16920 catcacaatg gacattcccg aggaacatcg ccagttttat aacacacagg tggggacact 16980 tgtcgagtgg atggatacaa ttccaactag cccgcattat cgctacgtcg tgcttctacc 17040 ggagcagaca tataacgatg gtgtggcaag ggatatcata atctccactg gtcaagacgg 17100 cttagtaatc gacatgccac aatccccagt agttggtgcc gaatacccat ttatgtattc 17160 agaagctggt attaaatcac acatactcat ttggaaagaa gaaggtacat taacaccttt 17220 ggaagatccg aagtatatct gggaacgcgt ggagtaaaga atgagtacac tgccagatta 17280 tctcaaacat atggagtttg acccgaaagg gtcaaatcca aataatttag tagaaatgga 17340 aagtcacttc atttcaagtg aagaagcttc gcatcagatt gtggtcccgt tatatggtcc 17400 ttttttcagt gcaaccttgt tcgatgcaca gggaaaagaa atcgataaag gtgattacat 17460 ctacggtgaa agattaccgg agttgaaagg tgattatgtc gaacgcgatg tttacatttc 17520 tatcctctta accaaaccac gtatgggcga ggtattcgtt agctaccaaa gtgttggtgc 17580 tgaactgacc aacttatcgc acctatttct cagttacctt gtttctaaaa tgaacgagcc 17640 gcgctctacg cattttgaca aggtaacgca caaaccccac agactaccag catttgaaca 17700 tcgccatcat tgggtggatt tcgtaaacaa gactgggtta agttccgcaa tcgctgaatt 17760 taaatcaggg gtagaaaata atcatcttaa caacaagatg agtgaattca ctaagttgca 17820 ggatagagcg acatctgcca cagctcgttt acaaggactg atgatagccg accatatcgg 17880 tgatgtgaac gtggttgcga atccgcatca gaccactgca acggatatcg aagctgagcg 17940 cgttaacaca cccgcaaaga acgccgatag atttttctct atgacgttct acgattttgt 18000 acgcgaattg tacactacag gcctagaccg tgtggacatt gctgactatc ttcgtaagtg 18060 gaactatcac gatcttgaaa acagtctgat agtacgtgtg ttaaactggg gaagaaaccc 18120 aattaacgga gtgattcaag cgactaatct atttagagtt gggtcagatg gtgccgtagt 18180 agaagttggt ccagaaggtg ctaaacttag gctaagtggt tcttcggtaa ccttcaacgg 18240 gcatgagtta ttcgaccgtg agaaagccat cgcttacagc gacgatatcg atggtaagtt 18300 gattgtggca gttgagtcag acgattttgt ggtttcgggt gacactacag aatttaaccc 18360 attgcaactg cacatcaaat acactttagc aaatccaaca acaaaagggt ttgctcgaat 18420 catcgatttg gctggtgagg agactgacgg ctacgtcatc agttcgttag gggctaaagc 18480 tattgatgat accataccca actatctacc aaagaccaca acggtcaatg gtaaaactat 18540 cgacaaagac attaacatca ccaacgcaga actgggactt ggtaatgttg ataatacagc 18600 tgacttggac aaagagttat ctttcctaga aagacaaaaa ctcggttcaa ttgtccaaga 18660 gaaccataac cataactgga acgagatcga ctttgttaag tcgactaagg tcctttacgg 18720 tattgataaa gctgctttgt cggtggtgga tgaaggtgcg gtttcatcta agttggctaa 18780 ggaatacgtt gatggtatca tcgacttggg tgaggagttt gccacaaagg cattagtctc 18840 taatttttac ttcgtcggtg ttaaagacgt tgtactgagt agtgatggtt cgcaggttaa 18900 tatcctcagc ggtaaaatgt tgacaagtat caacggcgtc gtcacagaaa cagaattgat 18960 ggctggtaac gtacagtacc cgtcagtaga tgcaggtaaa gtaaaaacat acctaatcta 19020 ttacgtcgat aatggtgaga caccaccgca ttatgaaatt cacgacacac tctatccgat 19080 taaatatcaa tcggttttgg ttggtgtagt gaataacggt gcagttttcc agagcactaa 19140 ccaggacccg atttgtgatt ttggtgacga tagctcacta gagacacact tggccgaaga 19200 gatgccacac ggtctcgatg agccaatcga aggtcttact gttgtggaga atgccgatgt 19260 cttcattcaa aacgatggct tcaccagtta catctgggac ggtaatttct acaaccagtt 19320 gatgttaggt gatttcacct atagttctgg aactggccat ctaatccagt cagcgggtgc 19380 aaacccaatg gggtggaaaa cgtttaacgg caaaggattg atttatcaat cttctttcgt 19440 ggttaagagc gaggataatt ctgcggcact ggatgtcacc aaagcccctc atagtgtcgt 19500 ccttggtttg aacaatagtg acagttttag aatgttgtcg tgtactgtag aagcaggtga 19560 aaaaccaaga ttctacgtag agagatggga cgttagactt gtcgacaata agtttgaaat 19620 ctatctaggg gcgtacacac aaatcaacgt cgtttgggat acacaggtca accttccaac 19680 ggatttagaa gagggtaacc attatcgttt ctactacgat gaagttacta atgaaattcg 19740 ctttgagctg actggtaaac aacacatgtt ctataaaggg acggtggttg gtgttactac 19800 cgaggttcag aaagaactcg atatactcct taagaatcct tgtgtgggtg tacgagggag 19860 tgctaaagtc cctatggcag tcggcccttc tatcaggaaa ccgtataaag aagagtatgt 19920 gggtaacgat tatcgctcac tattcagaac ttatgtttcc gctggtgtgc ttgaccgtat 19980 acgtgccaag aacatcaccc aacaaattga tttgactttg actgggtctt atgtgcttgc 20040 agatgatgtt atcgaactag gtaatatctc ctccaagttg ccaacgggct tcactaacct 20100 agagctggat attctgcgtg tcacacgcga tgctggtcca tttgataggg agattgatca 20160 cgaagttctg tctggtgact tgtactacgg cgcagagctg actttaaaca aatgggataa 20220 gggatacggt ttgtctattc gacgtaatga caacatccga ttacctctaa ctcctctcaa 20280 aacttacaat ggtgctgttg tcagcggact catttccgat ggtgatagtt tctcaatccg 20340 agtgcgggtt aaagcctaca acgtcctttg ggggataacc tcagatgact ggcaatacct 20400 ctgccacatt cttgcttaaa agggtaaatg atgactttgg catatgaccc attgggtact 20460 aacccagaga acttaaagag tgagactaaa cgtttgtcag atgcgcccaa taagtggcgc 20520 gtcatcatcc caacgtattc tcctttttat cgttcagacc tagtcattct agatgacgat 20580 ggtaatgaac tctttgaagg cattgactat tacttaggtc attactacaa agagttatca 20640 gaagctctga aacgtccagt atacggttct cttattttaa aggatgaatc actcgacgag 20700 gttactttct ctcgttacag agccgtgggc ggcgaccaca tggcggcacc taccgacgtc 20760 gctaactact tgtcggatcc aaactcccct gaccctcgtt caacggattg ggctgtaata 20820 cgtgtccgta aaattgacat tattgccaac ccacctccta cgaatataac agaggctcgt 20880 gcaaccgacc cagttacaga aagcttatgg cagttaaaag agacaatgaa gtctaacaga 20940 gtgagttcaa accaacaatt ggtggatttg actactcagt taattgacct aacctctctg 21000 attgtcgata ccagttatga gaaacatttg gatgatacag gtcaatatgc gcatcatcta 21060 acatgtgaag ttattggtgc agctaagaaa agcgacacag cgcccgatgt ccagtatttc 21120 cataatctgc cgtacgaaac tttcaaggaa cgtgctagcg attacgcaat gcaacctgtc 21180 gttttagaaa cgctattcaa tcgccttaat gacgagatga aaggtgtgat taaatttaca 21240 ggtgattatc aactagagat ctccggtggt gcacgtttca aagttcgtgg tgaagagttg 21300 gtaattgata ccatcaaacc cacattagaa gtggaagtgg tcggtgacaa tgttaagtcc 21360 ttattgtttg tttcaggtac tggttcgttc acgttaaagt caagtgatgg tgtctgttac 21420 tacaacaata aaccaatcat tacaacggat gaggttaaag aataccttaa cccgtctctt 21480 ggtaaagctg accgtgtaca ttacatcaac aatgccgatg tcagcttttc agggattggc 21540 acagactcat ctaaattaag cgccagtgct aaaatcaaac ttgctacttc aacacagacg 21600 ggtttgtttt acgttgctga taactttgct gctgataaag cggcgacagc agactacctc 21660 tttaagacgc tgaccaagat caatttattg gccgatagtg actttagtat caacggcgtc 21720 cctttctcag agaacatggt ctttaccaaa gacgctcttg ggttagagaa ggtgaataat 21780 actgcacccg ctgaaaaacc gataagtaat aagttgcgga ttgagctgga taaaaaacgt 21840 gatgctgacc acgaccatac gtatgccaat atcaataacc caaaaagagc ttctgtttta 21900 gaagctggtc ttgggcaatt cgatacaaac ataagtggta atgaacaacg tctagttcgt 21960 cgaaatcaga tggctacgca gaagagctcc cttgatgcga atgcaaagat catcgacgag 22020 atgctcaatc gcggttatct taaagggtac tatttcaagg atttggttat cactgaatct 22080 aatgggacag tgtctgtttc atcatttaag atggtggaga atgggattga gacagcggta 22140 gttggtggaa cgtaccctaa tttcacaggg tatatctctg tacttaacgg tgttttatcc 22200 accagtgcta atggtcgact tgtgtgttct aaggatgtag acgggttata catcgcccct 22260 aattactcct atggaatgac acgtgagtgg ctagagcatt atcatgatac caaagcccat 22320 gatagcgcta aagggaaagg tatctattct ctcatccaaa acttccccgt aatcgtggat 22380 tgggaaaacc cagtgatcaa ccctcttggt agttatcaac gttggtcaca tcagtataac 22440 atcgctgata agcccgcccg tgaggatgag ttgctttatt ggggatggga tggcgaacac 22500 ggtgcagtct tcaatacgga tgaatccgat acctttatct ctatccattc acctttgcaa 22560 gagaactatc aattcaccac actaatcgaa ggtgtgagtg cgagcactgg tgttgctgcc 22620 atagtcctcg cttctaagga tgttagtggt gaagaaaaga ccatggtgct gaccattgcc 22680 aactcagccg ctagtggtaa tagcaaccag ataacctctc ttattcaagt atgggaggat 22740 tacttccaac caacacagcg tttaatcagc acaatcgatg aacgtaccga aaatgttggg 22800 gtttgggatg attcttattg ttacatcaat gtcgtttact ctcagggtat tctaacacta 22860 aacgttatac gagacgtgtt ccccgatggt gacagagaca aagtagtaga attattacca 22920 aacacgatag agaatatcga gtcatggaaa atcacaactc gtgtattcaa tattggtgaa 22980 acagtacctt cgttggtcgg tcctaactcg tatggttacg gtgctcgcaa gctaaaggat 23040 gttaagtttc acatgctgca aagcttccgt gctgagttaa tagagacata tgcagcacag 23100 agctacttaa gggaaatcgc aaccaaccaa acagagcaag tggaagtcac accgagtaat 23160 ttccaagttg attttgaatt ggttgaggaa ggtttgttta aagggacagt caacacttca 23220 gactttatcg cactgatgga tacctacgac caaccacatg taatcgacta tgattataat 23280 ggtttagttg ttgatattta cgtgcgtttt ttgtttgttg acaccaacgg gactcaatta 23340 tatgagcccc ctacttcact accaacctca gcggttagaa ccatttcgat ggagtttgtg 23400 aagtaaaata aggggagttc tctcccctta tccctttatt taatttaaag gagagcgtaa 23460 tgcttagcca tttgaaatac aggctcgact ggactggtaa gctaccagaa aaccgagtag 23520 agtccaaagt gacaataggg gctactacga atcgcgcttt tgctttaccg atgggtccgt 23580 tctacaccga tgaagttaca atcatcgatg ttaacaaccc gcaagaacca cttgttcgtg 23640 gtgtggatgt cgagtatgtc ctagcctaca ccaagttaag ccgaatggct gaaggtaaag 23700 aaatctgcgg tgttatggta gttaaaaacc ctaacgtcgg aactgatttg gttgtgtatg 23760 ccaaccatgt aggtggacca tacgttaacc aatacgaagc catcattaag gctatcgagg 23820 atctacaact tgacaaccgt gaagttgact tctcccgatt agagggcatc cctgaaaact 23880 gggaagctgc tccgcattta caagacctcg gtgacatctt tggtttcgag tttatcaact 23940 ctatactggc cgagatgttg tcttcaatta ccgctggcaa aacacctgaa gttcaggcta 24000 tgattgctgg actgactaat gttgaaaaac gattacagga tgctgttaaa gcacaccgtg 24060 attcactagg taacgttcac caaacaacag cgcatcaaac aggcacttac aacacagaag 24120 aaatcgacac gctatttaac acagtgcgtg atgaaatctc agtagtggct agcgcccttg 24180 gtgatgttaa cgataagatt ggtattctca atgacaagct tgatgcaatc gagcgactct 24240 tcaacgaaaa cactaaaatc atcgcatcgc tatcccagga ctttaccaca ttaacggtaa 24300 cttacggtga tgtcaacaaa gctatcgctg atcagaaaaa ccgtgataaa acccaagacc 24360 aaaaacttgc tactattcaa actgaactgt cacgtatcaa tgttaaggca gatgagttgg 24420 aggcaaaggt taacgaaggt tccgatgacc ttttgactaa aagcggtggt gtagtcgatg 24480 gtccattaac agcagcagcg cttggtgtga ctaacccaca accgactacc gcacgtggtc 24540 ttagtttaat gggtgacgct gatccagatg gtccacctga ttacgggatg tttgtcggtg 24600 ctacagctac ttacaacggc cacggttttg taaatggtga tatggcgaca tatttccaaa 24660 tgctaggtgc aactaatcgt ggatggattt tccgtatggg ttctactaac gtagcgtcca 24720 tttctggaaa tggcgatctt cgactaaacg gtagaatctt tgctgacgag gatatccgag 24780 gatactcaga cgcaagattg aagaccgaca tcaaacgcat cgagaatgcg ctagagaaag 24840 tcttgagtat tagcggttac actttctacc gtgaaggttt gtctgagcgt gaatcgggtg 24900 ttattgcgca agagatcttg aaggtactac ctgaagttgt tcagcccgat gaaggtggtg 24960 atatccttac tgtcgcatat ggtaacatta acgctttgtt gattgaagcc attaaagagc 25020 agacatccaa ggtcaatggt ctagctgaaa agctcggtat tcctttggaa gaagtggatg 25080 ccttagcggc taagttaatg aaagaagggg gtgagtgatg ggtattgaac gcgatctcgc 25140 cgaacttgaa cgccgtacca cagagctgga aaatggcgta aatgggaata aggtaacact 25200 tcaaaccctc caaggtacgt ttaatgattt caaggacacc cttctaaatg ctgagggtga 25260 gatccaactc cttggtgtta aacaagacca gcaagatgta gccattggtg atgccgaaga 25320 ttctgtctcc aacacgtggg ataaggtcaa tggtattgac caagcgctta aggatagaga 25380 agaaaactct ctgaccaata agggtggtgt ggctaacgga ccaattactg caactgcatt 25440 cggcgtacca aatacggatg tgacaaaagc caaagggatt agtttgctag gaggcgctac 25500 attagctaac ctctcctacg gtgctttcat tggctccaca gttacgtacg gtaaacatgg 25560 ccaagtacag ggcgatatcg ccacgtattt ccaaatgagt ggtgcaagta accgcggttg 25620 gattttccga ttggggaatg acaacgttgc ttcgatctca ggtaatggtg acatgcgact 25680 tgatggtggt ggtctagcca acactgatat gcgtggttac tcagatagac gactaaaacg 25740 tgacattaaa gtcatcccaa atgcactgga taagattaat cgcattggcg gttatacctt 25800 tactcgtgtt gataaagact ctgataagcg ttatgcgggt gtcatcgcac aagaggttat 25860 ggaagtatta ccggaagtag ttagtctgga tactgaacgt gaccgctatg ctgtcgccta 25920 cggtaactta gtcgggttat tgattcaagg gatcaaagag caagacgcac gtctaaaagc 25980 actggaaatc ctagcgagtg aaaaacgcta atgggggaac ggggaaactg aatacttttt 26040 aacgttatcg ttagaatata tgtataggtt ccccgttttg taatcttaaa atatttaggt 26100 gaatgtatgc cattacaaac atcaggacct attagtttag gagatatccg cgattacttt 26160 ggtggttctg gcgaggttag catctctgat ttttatcgag gtggtggcat tgtaccagac 26220 attgctcaaa atagcaaagt gccaactagt ggtcaaattg gtttagggga cttccttggt 26280 gcgtatcgct tatcggtaag aagtgttagt aaaacaacaa gtgctgaggt ttcaaaaacc 26340 accagtatta caacttccta caccgttgca aaacaaacct ttaaacagac ctctatcgcc 26400 aaatcaattg gtaaaagtag aaacacctct tgggtaacca ggtggcgtag ttattggaac 26460 actgcatcgg gcaagtcctc agtgcaaact tacgcagact actcaagaac aacaaccatc 26520 accacatcat ggactagtta ctggaccagt tattggaata catactggaa cactgactat 26580 ccaacttcca aagtcacatc gtggacaact acgtggacct cttcatggac cacaatttgg 26640 aatacacacg tggccgtcta aggccacgtt ttactaaggg ttatttaaaa atgggtatcg 26700 agaaaagagt tgaaaaactt cgtctacgta ttgtagcttg tgaagagaaa tcatcaaaag 26760 caatgagcat tgcctctgaa tctatcgggg catgtaaccg ctttcgtcta gctgtcaaag 26820 aacttatgga gcacaccaaa agtaatggcg aggcgattgt tgaacatatc gcacaactcg 26880 ataccgagaa ggcagaagtt gtaaaagaat accgtgatga gctgaatcaa gtcaaagaag 26940 ggtttgatgc agcagtgaaa aaacttgctg aagagttaga tgctctttcg aacaaagcaa 27000 aagaactgga taagcaggag taagtgatta tggaactcag tcaattctca cgaactggca 27060 cagtgctttc tactgataaa accatcggta gccgtgaact ggccaagtac gcaatggata 27120 aattgaatgt cctgcatcct gaaatgaacg ttttgttcga tatgatgcat aatgatggcg 27180 aagcatacgg tgttcatgaa ttctgtggtg cactcggggg gatttcaatc cgctacctcg 27240 atttgagcat acatcaaacc atccttatgg agtcgattta tggtaagccg actaattttg 27300 tcgattactg tgaattgctt cgcgaggcta ctgttagtga taagtacgta ctccgcgata 27360 cgcaaatcaa agccaagcaa gttgtattcc tttctggctc aaacgtcatg cacgacaaca 27420 ttaattttga agctgttgat tcggctgtgg ctgaaggcgc tatcatcaaa ccgcacccag 27480 tgactcacgc caaagatatt cagtggctaa aaagccgtta tggtgaagac aaagttcttg 27540 ggcctaaagt atccggtgcg actttgttaa agcaggccga aattgtctac atggctaaga 27600 acagcgaatt atggttgcta gctattgcgc atcgtaaaac ggtccgctac gttggtaatg 27660 ctcacttcat ggcagaagtc tatcgtgccc caatcgacgc gatttgggga cacccaatct 27720 acatgccacg tattgccatg aatcgattat tctccgcttc ccaatccggt atctatttct 27780 ctaaagaaga aatcgataat ggtctgcatc tatatgtcaa acgtgtaaag gaactgtcga 27840 aatgatcact tacaccaaag tggtaagtga agagcaaatt aatcagttct atattttggc 27900 cagtagtttt acttaccatc acccggatag aatcttatat tgccaaagta gattaaccct 27960 gaaagaaata cctggggtgg tctaccttgg tttgtacgat gatgtggaaa cgtttggcga 28020 tacgttctgt tacttatcac cgcatatctg tttttttgct cctatcgagc acatattaca 28080 aatgaaggtg gatggacaaa tcatccctaa tgacagacct gctgttagaa acgatatgta 28140 cttctacaac aagcaccatc gtgaggtggt gatcgactac ggcaacgatg tatttctgaa 28200 tatgtctttg ccaccattta tcgattgtgg tagtgtcatt ggttatcgcg atttaaccgc 28260 aaaaacaccg atgattaata cacgagaatt taatccgagt atcaaacaac gaaatagtta 28320 caagacattg atcttcccat gggagcgtta cttccaagtg atgatgatgg cgggcggttt 28380 acttgaaaag gagtatatcg actctgtcgt agagaattgc aaaaggcacc cctacatgtt 28440 gtactattac gccaacggat acctacaagg cactgacggg gtataagatg tcgctggaat 28500 tgttagagtt gaagaactca ccgtatctaa atgaggcaat ggaaaaaatt gacctttgga 28560 aaaagaaagg gttcaataga atgttgttga gtttagagga taatcaacct gggttcattt 28620 actctaacaa tcgcccagat agccctgtag agtttaacga gtgcattggt agagtgttta 28680 aaaccaaatc atccccaagc gatatgattc cctgtgactt cataggcgtc tcggatggtg 28740 aagttttggc ttatttccaa tgcattgttg tttacctacc aggtggagtt tctagtgcga 28800 caggtgttaa gatttaccac ttgtcggggt cgcattacaa gataggtaaa ttacagaaga 28860 tgttttacga ctgggccaat cgaaccttcg actatatctc agttcaattc tctgccttaa 28920 atgcttttgc taaaggcgag gcttcttttt ccgaaacaca gacagtcaat gagaatctaa 28980 aaaaggcttt tgataaaaac aaggccatgt acggattccc aaacccaggt gtgattaaac 29040 atcttctgtt aaagtacgat ggggtattta taccttacca catctacaca tataacttgg 29100 atggtgattt ggatatattg cataatgtgc actggttagg tgaacgtggg attgagaaag 29160 gtcttcctaa gtactctccc cctaaaacaa gaccagagat tataaccaat taccttaaat 29220 cgaatggtat tgaattacca gaggacatta acgatgctac ctaatctcat tgttttaaag 29280 gattccccat acgttggaga aaccatgact aaaatggacg ggtggaaaaa gcaggagttt 29340 gctaagggta cactaactcc tgaaggtaac caaccacagt tcatgatagc ggattgtcgc 29400 ccagacgacc cagaagaatt caacaagctg ctcgggaaac cttttaccta tcgtgagggt 29460 gaccgtgaaa tgaccaccga ccactttgtt ggtttgtcac tcgatgggga ggttaacagc 29520 tatttccatc acaatatcga agagcgtgca aacggtacta agggtgcaac ttgtgtgcat 29580 tgttataacc tcggtgctac ttctttttta tttggcaaat accaaaagga attctacgat 29640 tatctaactg aaacgtttga ttacattgaa atcctaatcc ctgctgattc accgtacagc 29700 aatggagatg tgaatggtaa aggtattgaa ccttcacctg agctaaaagc agttatggaa 29760 cgtcgattca aagaaactgg ttaccataac ccacacttaa tcaatcgtgc agtgaagcac 29820 aacggtacgg ttacacctta ctgtatcgac cttccagaca tggacggcaa ccatcgttta 29880 caccacatca ttcgttggct tggaaaaccc ggaattgaaa aagggctacc taaccaccct 29940 gtgttgataa aacgaccaga ttcgctaaag gcggtattgc gtaaactcgg cattaccgaa 30000 tacctttaat ttcaaaaacc ttaacaagag ttatttacaa tgatggagag tacaggtatg 30060 agctgtttta tttctatgct gcctaaacta aacaacagct gttttcttga ctgtgactac 30120 tgcatggtag aacacgacga tatggaaatg gtaaaacgca acggccgacc ttcgaccatg 30180 atgccacttg agatgattga gcagatgtgt gatatggctg ttggctatcg tcgctggttc 30240 ttctcttatc tgggcggcga gccattgatg aatggtaaag agtatttccg cgaaatgttc 30300 gaaatcatcg aacgtaagtc taagcaatac tacgcacctt acacccaccg tgtaacaact 30360 aacggtctgc tactcgacga tgaatggatc gagttgttcc gtcaatacaa ctgtaagatc 30420 atcttcagct acgatggact tgggtgtggt aaaaaagggt ctaagaaagc acatgacctg 30480 atccgtaaat acgcaaaaga catccacaat gtccaagctg taatcggtgc gttcaactct 30540 caccgtttcc tcgatatcta taaagaacta gaagaaatcg gcatcaagca gtttaacaca 30600 caattcgata tctacgctaa cgaagacgag tacaaagcat tcggcgacca cactgttgaa 30660 gtgttcaaat acatcgatgg tctggataaa gtaactacca gcctgtacct ttacaacgac 30720 gcgaagaaca ttgcacgtgg taaattaagt gccatcaatg gtggtgaatt gatgaacact 30780 cgtctagtta cggattacgt cattgactac gacggtgaga ttcgtaacgg tcttccagca 30840 cgtgaaagca aatacgcgta ctacggcaac atcaaccagt tccgtaactg gcacgacttg 30900 atgttcactg ataccgctaa gtacatgatc gaagattacc tgaacgcgat ccatacccca 30960 gacccacaac tacacgcagt atctctactg actcgtggtg gcggttatcc aggcgaccgt 31020 tttggtattc gtcctgaatc tgcaccacac taccctaaac ttcactgctt taagaaaatc 31080 ctaaatcact tcgatatggg tttgtaatta gtagatgcgg tttttgttgg taacgggtgg 31140 actcagttac ctcggagcgc atattgttgt tgaatatatg cgctcctcac acattccaat 31200 attgctagat aacactaaag agacaaataa caatcttagg attatccggt ctttaacggg 31260 attcacccca gaggtacacc gaggaaatct gctaaacgat aagatgatga aagcgttatt 31320 ttcaagatac aattttgatg cggtttatca tctagccacc aacaacctag attctcagaa 31380 cacactgagt attattaata acaacgtcaa tggtacaaga aggttgcttc aatacatgca 31440 gcgcttcgat gtaaagaatt tgatttttgc atctacaaac aatatctaca acaacggtga 31500 ggttggtctt ttagaccaat ccgccgtacc tcttttaccg tattacagaa gtatccatct 31560 ggctgaggag gctgtgatgg agtggggtgg ggttagaggg aataattata gtatattaag 31620 gttgtttaat tcaatgggtt ttaaatacga tggagctttt atagagtctt cttatgaaag 31680 ctttggggat tcgttttact cattgtgtaa tttaatgcta aatgaaacca tcgaaccgta 31740 cttcgttcac taccctgatt tagaaagaga ctatgttcac atcagtgact tggtccgtgt 31800 tctaatcggt gctttgttga atgttgagaa gggtaagagt ggtatttaca atgtggggcg 31860 gggtatcggc gtaacgccta aagacctctc acaaatttac caagagttga cagacataga 31920 gttaattaaa actccaatgt ttgacaaagg ccttgggttg actcgtctgg tgtctaatgg 31980 tcctttacca tttaacacac aagccgaatt ttccgttaga gacgcattag aagaagcaat 32040 aaaatggtat cctgaacgtg actagctttc atcggctagt cacatacctt ttattttatt 32100 tttgtatcta aggaaataag tcatggctgg attcttaaag aaacctaaat tacgccgact 32160 gactgagaaa tggtatcagt tacaaggtga ccttgttttc cactttacgt taaatgaagc 32220 aatggcgggt tataagccaa tgctccgtga tttggttaag aagggaatag ctcccgatga 32280 aacaatctat gtggttgttc ctaagggttt cgtcacagat ttggcatctg tacctaagcg 32340 attacagttc atctttccgc cagatggtga gtatacttat gcagccatcg ttcacgatat 32400 ggcctaccaa tctttgaaag aaaggacttc cattgacaca agttcacatc gataccaccc 32460 aatacatgaa ctgaacaaac accacactcg ttatctcgct gaccgattat ttttaatggg 32520 tatgcgggag cttggtgttg atttgtttac aagaacagcg atgtataacg cggtacgcct 32580 tggtgggtcg tcttcctatg ggggcatacc gatggacgaa gattacggtc ttgcgattcg 32640 caatcgtttg ttgatggcag actcgtatct catttaccgt gagaaacctt cagttggggt 32700 tgagccatct ctatacgatg atgggtgtgc aggtgatggg gtggctgttt ttgtaaaaca 32760 tcctaacctg aaacgtgcct ttgccttttg attatttaaa ccgtagacga gtggggagag 32820 agttatgtct gtagctccaa ttagcatggc cgttaaaagg ccaaacttta ccgcacacac 32880 cgtctcaccc gaagagaagc aacagatact gtctagaatc aaccaactga atagtgagtt 32940 gatggcggcg ttgaacaatg taaacacgga cttatcacag caactgagtg atgaaatcca 33000 aagtacaatt caacgttttc aggcagtgaa tcaagagtta agtgatatca atagtgcgat 33060 taatagtacg aatagtaacc taagtacaat caacactgca cttactcagt ccattgctaa 33120 cttggatacc aagacagcaa caaatctagc cactcttcgt aaagacagtg aagatgctga 33180 tgcagcctta acggaaagtt tagggtctgc tatcgacgat tacaacaaca agattagtga 33240 actcacctca aacatgaact cgtacatcgg tacgaataat gcacgtgtgg gtgatctgga 33300 agatgagtta gcggcttatg taatctcaaa caacaaagcg ttgaatgatt acaaaaccgc 33360 gaataacttg cgggttaaaa ctttagagga taacttcaca gcctttaaga caagcatcac 33420 tactcagctt aaccaggtta acactaatct aactaatgcc attaaccaag tcgcaagtga 33480 cttggctgat tatgagttgt caaatgacac gcgtgtcaag gccattgaag atgacctagc 33540 tgcatacaag tctacaaaca atagctcatt gtccacttac aaaactagta acgacggtcg 33600 tgttaaagct atcgaagatg acctagctgc atttaaaaca actatcacta gtcagttgaa 33660 ttcagcaaag aatacacttc aacagaatat cgattctgtc aactctgctt taaatagcta 33720 tattgctact aacaatgcgc ttgtaacagc aatcgagaaa aagattgatg actacattgc 33780 tagcaataac caagcattga gttcttacca gacttcaaac aatgcgcgag ttaaagctgt 33840 tgaagacgat ttagctgctt ataagactac agcggcgcaa tctcttaata cagcgaaaac 33900 tcaacttcaa gataacatcg atgcaaccaa caccgcatta aatgcttaca agaccagtaa 33960 cgatagtcga gttaaggcag tagaagataa cttgactgcg tataagacat ccaacaacca 34020 agctctgtcg tcctatcaaa cgacgaataa tgcaagggtg aaggctgtcg aagatgacct 34080 gtctgctttt aaaacttcta gcggtaatgc acttacgacc gaagtgaata aactgactca 34140 gagtattaac tctgtctcat cttcactgag ctcgtataag acatctaacg atgcccgtgt 34200 taaatccgtt gaagatgatt tggcagtgca cttggctgct caaaacccac acggtatcac 34260 acctgcaatg attggggctc taactcaagc gcttgctgat gcacgttatg ctagactaac 34320 tggtatgact atgcaaggtg atatcagcat gggacagaga aaaatttctt ggtctgctaa 34380 caccgacggt gccgaaattc gtttcgataa cacaggtgac agtgacctag attcttcttt 34440 gcacatggtt gtgttggata acggtaatga gttcttcaaa tggtcgacac gcagcgctgc 34500 atccgcaggc ggcgttgaaa ccgagtggat gactctgaaa tccgacggtc ttcgaatcaa 34560 agggaatcta gtattccacg atggacgagt tcctactacg acgcaattgg gtattagaag 34620 tgacgctgag aacgacgcac gttttcactt gaagaatgcg aaagttccaa atgcaacgtt 34680 agctgataca gttacggtaa actgggcgac tacgactacg ttctttaacg ccctgtatgc 34740 tgatggtaac aagatcttca acactgatgc tttggtcatt cgtgcttcgg atggttacag 34800 tcgattgaaa catggtgtgt tagcaggcac ttatctctct cacaatgaga atggtcaact 34860 tgttgtctct agcacagcca aacgaagcgc tggtatgtac ggtgtttacg atgccgctaa 34920 gaccgcgcag atttggtcta tgggtgttgc atacaagatt gctgatgacg gctctaactt 34980 cggtaacttg tacggattgg catacaagca cactaacaac ccagagcaag gcacaatggg 35040 cgcagggcat cagatgttgt ggtgtcagaa cggcgtagtc tacgcttcta tcggtaacga 35100 tatctgggcg aagaacaacg tctatgcaca aggtaacgtc agtggatttt cggatagacg 35160 tctgaagaaa aactttgaag ttattgataa tgctttggaa aaggttttaa ctttaactgg 35220 tctcacttac gatagaatcg atatgaacga tgagcgtcaa gctggcttga ttgcccaaga 35280 tgttcagaag gttctacctg aagttgtttc gcagtacggt aagtacttga ctatctcgta 35340 tggtaattta acggcattgt tggttaatgc tattaaggag ctggcgaaag gtcaggggat 35400 tgctctacct tcaaatgact ttgctaagaa agcagagtaa aaaaaccaat tggaggatgg 35460 tatcgaccat cctccttttt tctattcttt ttggctataa aaggaaacaa gcaaatgaca 35520 gcaacaattc catttgaaga ccttgatccc ggaacacaag aggtgattaa taaattcaaa 35580 ggtaaatcac catctgtcga aggtctacca aacaccgtag tattgcgtga caaggagggt 35640 aacgtcttag gtcactatct tttgtcgaaa gctccaaatg ttagtgaggt atctggcgca 35700 gtagctttcc gagttgacaa aaacgatggg cgaatacagt tttgtgataa ccacgaagct 35760 gtaagaaaat tcctaggtct acctaatgtt tttataggag aagaagcacc agtatccccc 35820 ggagagggtg acttctggat agacgaagga gagtgaaatg gcctcttaca ggattgatta 35880 caaaaaatcc cccaaggata atgtagtcgg tataatcaat gcaaaaaatg aaaagacata 35940 ccctgcgaaa agaatactca taaagggagt agaggatgat tttagcatcg gtgggtcaga 36000 cacaaaaata aaagtcgact tactcaacaa tgggaaggat acacctaacg agtatgttga 36060 attttgtttt gcaaggataa aactagaaga cgtgtttaaa aacgtggaca tggcaaagct 36120 tgataagatg ctaccgagcc atgtgattga aaacggtttc gtcatggtct cttcatttat 36180 taaagagatg tatcgacgtt ttggttttta cctagatgag actaattacg actatgtggt 36240 cattgacaac attatcactg tccacgcaaa gtcgattaat cctttataca agggattctt 36300 tgaaattacc gtcgaaggta atgtgaaatt agagggcgaa gaagctaata tgatggtcga 36360 ggatttctca ggctatctac tcaaaatcga cgtatttcca gacagtcttt ctgagagaga 36420 ttttgaaggt gctataaagg cacgtagctt tatcagtagt gttgagaata ccgacactat 36480 tgtgggggcg atggtattta aaaacgggga taagttagag tttgtatctg acgtcagagc 36540 aataagacga gcattcaaag ctaacaacat atctgcgtct tcaactgcgc caataaaccc 36600 tatcgaatac gatctttgga tagaggacga ataatggcta tactaaaagt atggaaaaat 36660 gggaagtggg tgactataga cttctcaggc ggtgtgatgg gcaaagagct acttgtcaac 36720 cgcgacatca aaaatgcatt gaacatccgt aactttaacg gtaactggga acttctatct 36780 attggtcagt atgcctacga ccgttggatg aaagcgagtg ctactgagaa agggcaagct 36840 attcctgatg gaacctatgt ccctaacaag aagcacacag ttagttatct tttggatggt 36900 cagcgacata ctgaaactat tatgtctcct gcgggtggta actggttggt gaagttgcct 36960 ttcatcgcgg atgagatgtc tctcagaaag ggtgtgggtt ataccactca tacacctgaa 37020 acagaaagtg aacgtttatc ggcttgtcgt ttctttgctg aaacgcaaac tgttcgagta 37080 tcttggtacg atgtggttta tggtgtttac tataattaca tttatgagca aatgctgtta 37140 tctgacaaac accgttcccc agtcattata ttcgtaaatg gtacaaatcg aatcaatgga 37200 cgggctactg agttaatacc aggcggattt cgttatagca tcactagctt tgatgggaga 37260 gctagcggaa acaaatactt cgaattcatt gcggattcag agattagact agaggagact 37320 gtgcaatgaa catagaagcg cgctacaccg aagctagaat cggtgagaca ctcccctatt 37380 ctgttagcgt gattggtgag gtcaatgcca aacagttgcc aaggaatcac cccgattggg 37440 taaactgggg aatagatgtt ttagaggcgg aaggtaagat actgccttat atctctaaag 37500 acgccgaacc agaactaacc gaagacgaac tcacgtatcg tcgacgtgaa gatgccaagg 37560 tgacacgtga cttagctatt gaatcaccaa tcaaagtatt tggtgtcagt tatcaagtgc 37620 acgttacccg tgatgaacca cggattaatc gtgccatcaa tactgctacc gaggcgggtt 37680 atccagaaga ctatgcggtg gattggatac tcactgataa cactacaagg ccaaccactg 37740 catccgatct tcgtaaaata ttggtagcaa aagctttgag ggaagaacat atctttgcgc 37800 aatacaaagc ttggctggcc gatggtatga aagacgactt ccttccaata caaaaagagg 37860 attatctcga tgttctatcc tgacccaaaa caattctcgg atagtgaatt actcccccct 37920 gagattttaa agcgatgggg aggtacgggc aagtacctac ttagtccatt gatgttgatt 37980 acactgcaac agcttcgtaa tcgctttggg cgaatcagag ccaactcccc gaagttgggg 38040 ttctatcaac gtatgcttcg aaccgttgat tactacatgg accaaatgaa aagaaagcac 38100 ccagagaaat caggggctga gattttcaaa ttggctagtg aagcttatca acgatactgg 38160 ggacttcaca aagtaggtgc agccgctgat atcgatttcc ttgacgcaga ccgcgaagag 38220 gtaatcgaat acattcgtgc taacccggac gaattcccat tcatcagttt cattgaagtg 38280 gacatcactt ggttccactt tgatgtgcgc aaccagccag ggattacatt ctggtcacct 38340 aacgatggcg tcattgaggt gatagaacaa acccccattg actgggaaaa aattgtggat 38400 atctctggta agaatacgaa gtggaaaaaa taacgaggag ggggcttacc ccctccctat 38460 taggagagtg ctaatatgaa taaacgtatg attaccgtca tcgctatgtc attctgcttc 38520 ttactctttg gtctaacttt tctgtttaca aaaatagaag ggacgcagag taaggctgtg 38580 gcaaagattg tcgtcgaaaa gatggcttac aatatcaacg aagtcgataa gcgtgttagg 38640 gacgtactcg ccaaagttag aacaaacgaa acattggatg cgttaatact cattcaagat 38700 gacttcaatg actctggata tatggttgat gataaagact acatttccta ttctatcaaa 38760 cacgacgggc tggatagagt tctggaagtc aattacaact actatttaga aaacagtggt 38820 tacatgctag ggaggtactt tacagttctc aacgattaca aactaatcgt cgttgatgac 38880 agcactaagg ttaatagaaa ggattttcgt gaatggttag ggttgagcga ccacaactat 38940 ttgtatttct cagaggcact taagtttgac gatggcgcat cgctgtatct agtcggttat 39000 gtaaataaac ccatgctgta ccctatcatt tatccgcaga gtgtgcaaga taggatctat 39060 caattacttt atatcgttct cttattcata ttgtcttaca gcttaatctc caatatgaat 39120 aattactata tgcgtcgtga ggctaggata cgtgatacac tcactgaccc actaactgga 39180 ctttacaatc gacggtatct agataagttt attttcacta atgagctaat agtcgctatg 39240 attgacctag acgactttaa agagataaat gactcaatgg gtcatgttgc tggagaccgt 39300 gcgttaaaga gcttctcaga ggccttaatg agggctacgc gtaacaacga cgttgttgtt 39360 cgaatgggtg gagatgaatt tattatcata cttgaaactt ctgatgtcaa tgtcatggaa 39420 gaggttatta aacgcattaa acgttttacc aacatcggct tcagttgtgg atatgagata 39480 tacgatcaaa aactatcctt tgaagaaaac cttgaagcag tcgatgctcg attgtacgag 39540 gcaaaaaaag aaaagcgtta aaattaaata cctcctagct taaatgctag gaggtttctt 39600 ttttattcgt cgtgtggcag aatctcaatt ctgaaataat taaattcatt tgagaaaccg 39660 ctatcacctg atagacgatg gtcaatctca gacagggaca agtcaagaat gacagtctca 39720 tcaataaact cttcaccatg tggtaacagt tgatggttga tgtgcttctc tatgtcactt 39780 ttgtaccatt gtaacatatt gcgcatatgt ttactaaccc cgactagatt gtaaatggtc 39840 tctaacccac caatggccat ctccgttaac ttatcgcact tcgggaccag ttcttcgatg 39900 ctctcaataa cgggtgggat tgtcattgtg tattgctggt tagcataggt aacacatagt 39960 tttctcatga ttgtttgtcc tttggctcaa ccttgatgtt gttgattaga gtgtcgtagt 40020 cgttaggaac gaggtcgcgc agtttatggc acatctcgtc catgtcattt tgtttaaggt 40080 cagtggggtg acgaatgccg tattttattt cacctagtag caaagccgct tctaagatgt 40140 catcaggata tcgatagatt ttgtctgtat ctttctctac gatgacagtt cctttcttaa 40200 gggcctctct cgcttcgtca cgaagtcgac cagaagttaa accttctgat gcatccttgg 40260 ttagtaacgc gtacaccaaa tccgcaattt cataaattgc attaactgag attgtttcag 40320 ccatgggtaa ctcattgtct ttttccatta tatatttcct ctttcttact aaacagccat 40380 ggcatattca acagggtaag atttctcaga acctaaatct ttgaagttta taccatccct 40440 agttttaaca actttaatgt tgcttaaacc aatacctaga cgtgctaatt gttgttgggc 40500 gctcttgagt aactcaattg catttgtaaa cacgagtggt ccatctgaag tgtctacgtc 40560 gtccaatagt aagactgttg ggacagtctc tgactctaga gtttcttttg gggttaaaac 40620 cataaagtta tctaggttga tttgcttaga tgtgaagtcc catactactg gtttgatagc 40680 caatgacatt ttatttaatt ccttctaatt aggttaatag aacaagatgc tttatcaccg 40740 taataatata tacctaagtt atttttagag aaagaaaata aaaaaaagag gggagaggta 40800 acctctcccc ttagtagtta gaataaccgc aaggtatcct caactattaa gcaattctct 40860 ggcatcttga atggctctat gtactcccac cattcagaac cgtcatactc accacgttta 40920 agaaaagaac catcaggaaa acctatgatt agatccaaag gtatctcgtt gatcccatat 40980 ccatcgtcgt ataagaaatt tgctcttttt tgaaacgtag cccatgtcat cgttatatta 41040 gtgttagcta atccaatgaa tataggttcc attccagctg cattaacaaa ccccatagtc 41100 tcttctaaga agttaaccat tgtatttacc ttatgttgat tgacaatagt ttagtctcat 41160 caacatggat aaaaataaag tttgtttact agcatagtat taagaaacgc agttattttt 41220 aagggaatgg gaatagtgac gtgatttccc ccaccccgac attaacctgt tgatttattc 41280 acaggctaag actattttgt tcgaatcatc caatgcagcg atgtctcaaa acccaaacgt 41340 tcgtacaatc gtttagctgg attgtttggt actatggtta acatctccac atcggcattt 41400 tcgattagga atgtcgccag ttccgtaccg tatcccttgc cacgatgtgt gtcttcgatg 41460 taaaggttgc tgagggattt tgattcggtg tggagagtca ctaccccaac aacctcttca 41520 cccaaagcgt aaacatacat gttattcaga taagattcaa attgataatc caaatccatt 41580 tcttcgtaat tgtacggctc ggggatatta ccttgtgcca agaggatttt ttcttcagcc 41640 atcaaacctt taaagaaacc gattaccttt tcgcggtaaa tgtccttatt taagacagtg 41700 acttgaacta tctcaccctt aggcgattgc tgctgctccg actccaacaa ctgggctagt 41760 tggctgctca ttattttctt ccttcttagc aattttatag aaacgattgt acgtttcttc 41820 attaatggtc tctacaccat tcgcaaaact tggtacgaat ccttcaatga tgacagggat 41880 tttgtacttg gttgttagcc aatggtagat gatgtcacgt tcatcgtacg aacccgtttg 41940 attaatttca gccgactttt catcgtactt attaatcatc gccgttaact tcagggtgat 42000 tttaaaatta cctactggtt cgaatacggc gtctagcatc aaatcacttg catatcgtgt 42060 gatgccaaca ttttcgatat cttgtagaat aacgcgtttg atgaagtcag atgggatgtg 42120 acggtaagtg aaatggatca atcgctctat aggtgtagca cgttcaatct ttgctgtgaa 42180 taatcccttc tgaccgatgt cccaatgaat gacaccgtca ccctcccccg agaacagttc 42240 caaaaattta agtcggattg attcttcatc agagaatact ttggttatat ctgccaacga 42300 atacatgaat ttattttcct tctggctagc acttactttt gtggttcata ctatcggttt 42360 taaaagttta aaaaaataag gagggggcga acccccttcg ttattgttta atgaataacc 42420 ctagtcttag gttatgcaac ttcaccaaaa gtatgttatc cttgaaccct acgactcgac 42480 agcgattggc ggtgtaagtc attaaccaaa atactttaaa ctccgactct gttagtttgg 42540 agataaattg tgctaccttc ctgagctttt gatgctgaac tttagacaat ccagggaaga 42600 gtacgtggtg cggcaaagaa ccttcgtaaa cttgatcacg gtggattgtc acatatggcc 42660 acgattcatc tctgaatgct tgcatttctt tatactgcgg taacaagtcc atagtggcgc 42720 tcaggaactc tctgagacac gatataacac gaacatattc atttgtatta agttcataaa 42780 gataccctag aaacgactta gggttataat caatatggtc caggttaccg atagaatctt 42840 cgatgtagat agatttgaac ccgaacatat tcaataggcc tttttcctcg atagttaact 42900 ctgtgaagca gctgtcttct gttaacttct ctagagcgtc gcgtatgttg ggatatcgtt 42960 caatcaaatc gatatagttg tttttctcgt tggtgctgta atacttacga ttcattttaa 43020 ggtttcctct agtcaaccca aaacaaacca cctattcaaa aactgctacg ttgagtggtt 43080 gccttggtat attcgaatcc atcatccatg ggactgaata gacaaatact ttcggagcaa 43140 cttccactgc ccccttcttg atgttttcat cggttaccca ataatccaat tcttcacgag 43200 atctctttgt gatagcaggg actaaaactg acaccgttaa gcaactaggt gcgatgtcaa 43260 actctttatc cgctatccac ataggtggtg cctcgatgaa aatagaatct acatatccag 43320 ggatttgctt ggatagaaga ttggcaatct cgacaatatt catacgttta aaaattcctc 43380 gattaaaata aaaaatagca gggagcgaac tccctgctaa ggtctaattt acccgatatt 43440 agaatgggcc gaattcacga tcgttgtagc gttggttgta accgaccaat ttcactttag 43500 aaccttgtag tgtttctagt tcagccagag tgatgaattt gttgttctca acattctggt 43560 agtagctaca gcagtaatgg ccaaagttac cacgttcgcc ttctttaaca tggtctttgt 43620 tgaactgttc acgttcaaag tgccagttgt acaaatcacc tgcttcaatt tcaagtggct 43680 tcggatcagt ttgttcttca acccaagctt ccaagtcagt tgcaggggac aggatttcga 43740 ttgaagagct cttgttgtgc cagccacaag tgttaccaac ccaaactttg tcctcaccac 43800 ccactgcatc agcgatgata gatttcacat tgtccaggtc ttctacagat gatttctcaa 43860 cgtgctcgtt gtatgcattc accagaacat ccagctcttc tgtgtaaggg atatcttgag 43920 cgaaggccga gtcgtagtaa gccgcacaca gtgtacgaag agaacgtttg aagctgttag 43980 tacccatacg gtgcattggt tggatagcac ctagttcttt ttgacgagca acgtagattg 44040 aactgatcaa gctgttttgg aacaacacgt cgatttcgtt aagcaatacg cgacgttgag 44100 atttgttctt ggttacagcg ttcgccaatg ttttcatttc acgagatgac gctttagccg 44160 cagcaacaac aagagcagaa gcaagtactt taatagtgat catgggtcat agttcctttg 44220 tttaaggtat ttgtagagtc ttctaaacca atagggtgac atcctaagaa tatggatagt 44280 cttagagtgc cgtattcctt ttcctttaaa agacagtcga tagactctgg gatacaagtg 44340 tgattgatga gctcgatttc ctcgtcagaa acatcaccga ttatcacacc catagtatcc 44400 tcttgagcgt tagaaattgt tgcgatggtt aagctgttag cgtcaccacc tccttcaacg 44460 tattcgtcaa tggtctcttt caccgaaaga cgaacgtatt ttaagtaatc aagtaggtct 44520 ccacccatag aatcaatttc ctacgtaaat aaaaactcac ttttcttcca ttacctccag 44580 ggacattcta gaggctacac ttttgactat acccggatag tcgtgttccc taagagcgaa 44640 accagttcca gcctttaaat cttccaactt gattaggtgc ttatgttgat gttcaatata 44700 gtcccaatct tcaaccatgc gtttacagca ccagtcgaaa gtttcatctg agcaaattcc 44760 ccgtgcttct ggatgcaggt aataaagata gcttgaagtt aagaagcagg ctataaatga 44820 ctctgtcttc tccagctcgg cgcgagtcca gtcattagat gacttaacac caattttacg 44880 attgacgtgt aactcatcgt gtaaaaaaga ctcggctaat tcactacgct tctttaaagc 44940 ttcttcaagg gtatccctca aatacacagt catcttgtat ttagatttct ctgtatgatt 45000 tgcctgcatc acagttgaac ggaaacgtcc attctttaac tgtgtttcaa actcttcctt 45060 tagcacctcg gcatccttcc caataccgag gtagaagtgt ccactggaag tattcttaaa 45120 actgtagacc tcgaatgtca tacagtgaac gggtattgaa tcttcggatg tgggttatag 45180 tccactaact cgaagtcttc gcgtgggtgg acccaggtac gtagatcttt cagggtcttg 45240 atttccgggt taatcaacaa ccgtggcatt gggcgtggct cacgttccat ctcttcttta 45300 aagagttcca actgattttc gtatacgtgg taattcgaat gggtatgtaa agcactgcca 45360 cccttattac ccgtgatttg ggccatcagt cgacctagga cataaacctg tggtagattg 45420 gaaacgacgc caagtggtgc atcggatgag cgctgtgtac tgttgagata caaagtctta 45480 tccaacaatg tgaagtggtg tgagtgcaaa cacggacgca gacaccctag atggaacata 45540 ccagggttcc agaaagtcca gatttcacta ccatcatctt tacccgcttt aagattgttg 45600 taaatcttat ctagcaggtc gatagaatca ctgtgcacga agtctccact taacccataa 45660 ggtgcatcga gcttaggcca gttgttgcct acagcaccat agacaatacc catgtcgtta 45720 tcgcctttac gattcgggtt atttaaccac gcttcgtttt tattggcatt ggcgtgccaa 45780 ctaggtgcca tgaagtcttc aagtacctta gaatccgttt caccgcgtat ataacacaga 45840 agttcaccaa tacccagttt aatcggtgac tcgcgagttg tgttgagtgg cacgtactcg 45900 gtgcttaaat cgatgttaaa caccacattc gggatggtta aacgtcgagc gttatttcgc 45960 tcaaccgtga accacttacc ttcttttaat agacgcttac cagcatcctg atactgtgta 46020 tcaatcattg ttccaatgct ccctgagttt tactaaagtt tacttcaccc ctggctttca 46080 aaagcgcaac ggtgttttct gtgattttga tggccacgtc aacatactgg atgagtacct 46140 cggctttgtc ttgattcgtc ggtgtgtaaa caaacgttga caaaatgtgg gtctcgaccg 46200 ttgtcgggat ttgatttaga ttaagttgga cgtctgctat cgcattaccc agttctttaa 46260 agaactcgcc ttccaattcc ttattaatat caagatgata ataataatgg tcaacatcac 46320 caggtaactc ttgaagaaac ttattcacct tgtcacctga tgaataagaa ccgtcaaaga 46380 gtagaagaga cgaaggatgt tgttgaatgt agtttgcgac gaatgctaga cagtcagccc 46440 gtgtcatgct tggagtagcc attgcgagtc ctcagctaga cgtaaacaat cacgcttgtt 46500 agccacggca ataccttggg ttaactcgtc gatggttccc gtactgatat aacctagttc 46560 cttatataga gctaggtgat cagagattac ctttggtaga gagggggttt ctttaattaa 46620 ttcgttaacc acacgggttg gtaggaaaca tagaggactt ttatccgcta atgttttcag 46680 atagtgtggt ggttgaatat ggcctgcaat gatattcaat cgtgaattaa tcataccctc 46740 gataccgaaa ccgaacatgc cgcgaatttg cgccatcact ttagtaccaa aacggttctc 46800 caaggtgtgt tcgttatggg ccataatctc cagaataaag aatgaacgaa tctgttcttc 46860 tctcaattca ccggagtcaa tgaagtcacg ttgaatgaag caactagtca cttcctcacg 46920 caccgtcttt agacgaacgt atcccgtgga tggatcgtaa acgaagttac gtgtctctaa 46980 cttgatactg attcccggcg tgtgacgggc aacgttaaca agcatgatgc gtagcgcttt 47040 acaatactcg tgaatttctt taccgtagtg tttgataaag gctttgtgta acgccttata 47100 actggtgcct ggtttaaggt tctcgtataa gaacaaagca gcttcacgca atgcctttgc 47160 tgttgttaac ttgtacgtct ggttattttt ttccacgcgt tcaaaggctt tgttgatacc 47220 gtcttcgata acactcggtg gggttaaact atctactaag accattgttt tactttgtcc 47280 ttatctgatt aggtcgtaag cttctttagg gagataacct tcaacagcaa tatcatgcac 47340 tagctctttt gcacgaatca agtccccgcc atgtagtaag ccagcgcgga aaaggatttc 47400 aatttctttt ctagcaactg ccactaagcg attattcaca tggggtttgt tgtaggttga 47460 gagttgaatc aggcaacgaa tgaacgttgg cgggagacca gaataaccat ctgtgtcttc 47520 cggtttaaac aaacgcatac cagactcata ctttgccaca attttactgc ggcgattaaa 47580 atgcggacct tctttgaaaa agccaaagat atgatccaca tagctaggtt cgcgatagaa 47640 tcggaatact ttatcttcgt gctgatttaa agcagctttg aatatttctg ttttggtagc 47700 cgtactagtg gggtgggtgg agcacattag actgtccatt acatcacact tgaaacggaa 47760 atcactaccg catactttga cttcgcccgt gatagggtaa atagtgaaag cgtgtcgtga 47820 acgaatagag acatgtcttg acatctcatc gttattacac gttcgaaata atcgcatcat 47880 ctcatggtat tttgcgcggt aaagaatcgg gtctttgtgg cattcgacat agagagcttc 47940 ttgcaattct tcgaaacttt taataccatc aagtagtttc agatagtaag cgtgttcttc 48000 accaaagtta ctgataggcg accaagcgcg ttccaccatc tgtttaaaga aatcaagcat 48060 acgcgccccc attgcgttca cggaaagatt taagctccaa ccattcttct ggtgggaggt 48120 tgagtagatt actttggtta aacacatcga taagatgatc gatgctttgc gacacatcca 48180 ttgtggtatg tggtgctatt acccagaacc atgagcattc attaccatcg gcgcattctt 48240 cgataaagaa gcgcatcatc tcaggaatga actcattcat aaactttgaa gtgactttcg 48300 gtacaacacc ggattcgaag ttgtaataaa cttcatcatt cgttttgtgt aagacacaaa 48360 ccgtatactg ccaatcccgt tcgatggtct tcaggttctc aacgaataaa tcggccaact 48420 catctttctg ctttttattt ttgcaacgct cgaataccaa ttccatattg aatgtaatcg 48480 taccagattg tttagaagaa ccgatgtagt aatcacgtag agtgcgggcg atagcattac 48540 ggtataaaat tttcatattt aaaattcctt ggttgttgtt aaacgatgac attaattaaa 48600 ggtgtacggt atgtgcgttt tacctttctg attttgtttg gtgatttgca tccacctatc 48660 acacgctccc caactggagc agcacgtaac ttgagaatag ttttcaactc ttccacattc 48720 acaaacattt aaaatttcct catggtgtat taccattagg ataatatata actgttttga 48780 attcgagttc gtctactcca tgtgaaagcc acggaacgta aaaaaagaaa aaaaaataag 48840 gaacccgatt gggttcctta cattcactac aattgcttag caacctttcg gtttcacaat 48900 tgtagttggg tcgatgcctt gcttctcagc gtctttcact tgttggcgat acattgtaca 48960 tttaccaatg ctgatattgt acgcgccaga ttctgccccg gcgttaccac ccattgctgc 49020 tgttgcttga gatgcgaatg cgattgctga tactgctgct acgatagcga tgatgttttt 49080 catggaatgt tccttctaat tactttgttt gatttaagat tactttgttt ggtattaagt 49140 ttgtttgtta actactgact tagcagccag caggtttcac gattgttgaa gtgtcttggc 49200 cagcttgttc tgctgttttg acttgttgtt tgtagattgt gcatttgcct acgcttacgt 49260 taacagcgcc tgagtctgca cctgggttgc caccaagtgt gccgcctgct gttgcgtttg 49320 ctgcgaatgc gatagttgcg attgcgattg ctttagtgat agtgttcata gtgtgttctc 49380 tctatattaa gattaaattt aattaagtat tttgattata aggaatgatt catcacacct 49440 tattcactaa aataatatat atctgaaatt atttggaatc aacctttaac ccatataggc 49500 caaagtaggg cctttgcagt aatacgtcgt aaacccacat tagggtactt acaatatatc 49560 accacccaag cccaaacaaa taccacgaag taaaagattg acaatacccc tagtacaaac 49620 ttaaataaca tttttactct ttggtttaca tgcaacaatt aaagaacagt aaaaaggttt 49680 ggctagattt ttcacccatc taccttccac cattttactg tgacttagga cccatagtaa 49740 aaacttctct agcttagttt cagggatgag gaggtattga ttttcctcct ctctaaagtc 49800 atttaaattg acgatacgca ttatccaaag aagctttcca ttggaccgat gccaggcatg 49860 tgatcggcgt atagtttcga ataacgctct gctcttactt tcgatttgaa tgcacgtaga 49920 tggcactggt tagggtcgaa gtaagtggat tggaaatggt ggatatttag aacaccgtgc 49980 atgttagcga tttctagcat cacacccttt gttgggaaat ggtatttggt aacaacaacc 50040 caacgtgggt ttttgcattt tggtcgatga tgaccgaagc ctaacttctc catcagctct 50100 tcgctgtatg gtaggatgtc ataatcaccg tgttcacttt cccactttgg tttcttttcg 50160 ccttcgtaga aatgcacacc aactgcttca gtggaggtat tatagaaccc cttcactttg 50220 gcttccatca caggcatacc tggttcggtt atatagatta cacgaccatt gaacaaatct 50280 ttaaagccga gacgaatatt tttagttttc attgaaatga tttccttttc ttaattagga 50340 atatgggttg atgatttcga ctttgaaagc aatttcctca gtctcgtttt tgattctgaa 50400 agagtaggat tcgtgaccca ttaccttctc attcatggtg gccagttcct tactaagctc 50460 ttcaccgaac tcttttgaac actcggttag ttgaaccatc gttaattcgc tgaagtaagc 50520 cattacgttt tctgttggtc caacaaaaga catctcaaaa tcgtcttgtg cttttcttgt 50580 ccccaatacc attccaagta cattggagtg gaagtccatg attaacttgg ttctcattac 50640 gactccgtct tcaggatttc ttcaccacaa cattcgaagg agccttcatc atacttctgt 50700 ttcaagaaga taaccatatc catagagtag tctttacctg cgacaaaacc cggatcgtta 50760 gttgcttcat ttggattgtc agttaaagac caaacatcta ctttttggcc acttcttatt 50820 tcatcgacgt ggttacgtat gtacttgccc gtttttgttg aacgcatgaa catcttattc 50880 atttttctat ccttgtaact aatacattgg tggccttcac attgtagtgt atgccattat 50940 agagacagct aacaaatgca ccgtaagagt tgatgaatgg tttcaccttc tctattgatg 51000 cacccgcagg gatatctggg gttttcttag ctatcgctgt agcaatatca gaatcgttac 51060 atcgctccac tacagtaaat gtgcagtcgg ccagaacatc tttggtccat cgaccatttg 51120 cgaataatgt acctaaaggt gacatatcac tcttctccca tttcggcata aagaataatt 51180 gcagagactt cgaataaggt ctcgccacat ttgtaagaaa actcagcagc gttgtgttgt 51240 ttaatccctt cttttatctt actcaaacct tcgttgatta gctcgactat ggatgggggc 51300 gtatcgacat cgaaagcaac gttaatgcgt tccactaaac atcgtaactc aaccaaattc 51360 ttcgagtggt aatgaacatc caaataagag atagggaatc catcgctatg aatgaactta 51420 acaaagttac tgttaagttt tagcatgaga cgaagattat ccattaaaca actccttcaa 51480 tgtcatgttg ttcttagggt cgaaggtttc atcgtaccca tccataccag gtaaaagatt 51540 tttgttatct ggtagaatga tgcgcactaa tttaagtttc tcgatgtcgc caaaggtatt 51600 gatatcgtag aactcatggt tttcaggtag agtgtcaggg acaatgcgta cacgacatgc 51660 ccccaccata ccacgtaatc ctgcgttcct aacaaagact tcttttggct cagtgatgct 51720 gttgatgtcc acattatcga gtacgtattt aaatattgtc gcaatggcac caacaccaac 51780 aaatttgctg acaagtacca catcagtatt attaaacaac gagcctgtaa aactgaacat 51840 gaaattctga gtaactaaca tggtgagttt agggtcagtg tcatgcataa gtatctgttg 51900 gcgagtctct tctctccaac gggcaatatt gtgagctgtc ttgcactcat cgcaaattag 51960 tatctctgtg ccaatagcca atttgaagac tgaaacgtct gtcatatctt ccaccaacac 52020 gacattacag atcgggctga tattgtcccc ggtttgcaaa tctttgatgt gcttgcaaac 52080 caacgcacca gggtatgctg ctttcttcat tttaaaattc ctctataagt atttactgga 52140 aaggtttcca aacatatggt aaacccatca caccaagttc tttgaagtcc ctgatagaca 52200 taggaccttc gacatcttct aattcttcaa ctgagaatat gatttttagc tcagggtttt 52260 ctggtagggg ttcggtatca cgccatgcaa aatccacgac ttctttattg tcatctaata 52320 gagattcatt agcgcgttga acaccacagt cgttcatttt taaaatctta cctcgactat 52380 ctaaacgtct atcgccgagt ttgaacagta ccccattgcg cttccatgtt tctacagtag 52440 ccatcgtatc ctctaatcga ataaaaaata aaagggagca gaagccccct taacccttac 52500 ctttgccagc tagtttcaac agtaacatcg gaccccagat ataaatatgg cgtatccatt 52560 gatgtttact cttcggctca cttaatagta tcaccagtaa tgcttccgct aaaccagcat 52620 agatatacca ctcgagtagc ttagcaaacg caagcatcgg tatacaccca atcttgagaa 52680 agtacgaagg cttttacttc ttcgaggttt aggtttggcg aagaaagctc catggttttc 52740 tgtggtttga tgattaggtt ctttccgtca actactactt cgccaacgta gagtaccaac 52800 tcaccgattc cgtgtttggc tttaagcttt gtcagttctt tttcgattgg tttaaaatca 52860 gaacgttcaa agctggaggt tggctccagg attagatgtg cttttggcat atccacaatc 52920 caacgaatgt tttcaccatt gtagtaagcg atgtcgtttc catatactgc tttgttcatt 52980 ttaagttttc cttattactt aactaggttg tagagttttt gtacgatgat tgcttcttcg 53040 gtggctaacc agcaacgtcc attttctgtg tagacgtttg ctatcagccc ccagatttta 53100 aacttcatca aagccatgtc atttgacttt gagccgacca cgttgacacg tgcaatatca 53160 cgcaccttgt aacgatttgt ggcgatgtcg attagatact cgacgttctc cacggtgaga 53220 ttggataata tgctatggta cttggcaata tcaactgcgg taaggtccaa accagtagct 53280 tcgttaatct ctttacgaga cttatcctta agtccactga tcccatcttt aattttcgat 53340 tcacccaacc acatagagga ttcgatatcc agagctacag tatcgtcatt tgaagaaaca 53400 ataaccttga ataactcaat gtgagtttcg ttacgttgca tgtaattaag gcggcaaagt 53460 aaggtatcaa tgaatacctt agcggggtta aatttggtga attgcataaa cagcattttc 53520 tttttccaat caaccaacgc tgtgtttact tctaggtcac aattctttcc gcagagaaca 53580 atccaatcat tcattcgcaa accgactatt ttgtcgacta tttgagaatt aattcggatt 53640 ggtgattggt cttcaatacc aagctctaag cggattgtgt taatatccaa cgattgtgtt 53700 gtttgcataa ttcaaaattc ctcttcatgt ttacagtagg gtttagtttt taaacttggc 53760 gtatcgcgat gccactttac gttttgtttc tgttaactca tcttttaaaa ttaaagttac 53820 acggttggct aatattccat ccagcaacac atcgtaattg tcgaactttt cctcgtcaga 53880 gataagaagc tgtaatccgc caaccaccga aaccttttca tcagcggtga cgacttcttc 53940 taacagctct tcaattaaat taacatcatc aatagcgata ataatacgtt ccataaataa 54000 ctacttatgt tttccaggtg tgaaagttaa ggggccatcg tcgacaacag taatcgaatt 54060 gattccgaca atatctagct cgtgggcgag taggagatta ttctttcttg taaggtactc 54120 gttggaatcg acagctaatg tgtcaccttc gaaatccaac atattgtata gcttccagtg 54180 gattcgtgat aactcttctg cgaactcttc aattttccaa cttcttttga tgttggtgtt 54240 tagcgcagta gagctcggtt tgattttctc tattaaggaa agatacgtgt caaattcagt 54300 attgtttaac tccaccgttt ctcgtttacc aacgaggtgc caacaagcag tttcaataat 54360 gaataactct ttggctaacc cttcccctaa caaacccaca taacgataac tcgcgcctaa 54420 catgtggttt ggtccgacga tcatcgccat ttcttttaat gtgagttctt taccattcgc 54480 tttattcttt aaagcaaact cgatcgtttc tttaacagtg taacgtccat cgccgtattt 54540 ctgatattgt tccatagtct ctacctcccc ctgtataaga attgttcggg gcgttaaata 54600 aaagaaaccc cctatcctct accgaagtaa aggagagagg gagagagtcc atatagataa 54660 catatacccg atattattta gaaccctgaa caccaagacg cagatcttta aacattgctt 54720 tggcgatatc ttgcaatgtg taatcatcgt tagagtcaat aggttcaacc tgattaatgg 54780 ataagtatcg catggccatc agaagtatga atcgagaatt agcacgtagg ccgtcaccga 54840 catctatacc agtctgttta attggttcct ctaactcatt aagataagtc agaagggcgt 54900 cgtcgaaggc tgtttgtgcc accttgagtt tttcaatcac cccggctgat ggaggaagat 54960 tatcacgctc agggtctaac atacacctca cttcataatc acacatctcg ccaacaccga 55020 tctcgtttaa gaggacagcc gatgtcaatt cgacgttcat taatccaact aaagcctttt 55080 cgaattcccc agggtcatcg acatcaggtc tttcacttga atctattaaa ggccaatact 55140 tcatcgctat tgcggtgtat atatcgccac tagactcacc gtctcgaaca tactggtcca 55200 tatcgagctg atctaaatca aataaagttc ttgctgtggt agtttttggc ataacacccc 55260 ctattgaaat tgtaggtgct gatttcgtca caataacgaa acacactcgg ttaattcaac 55320 cgcatcagct tcttccttag tcaatataaa accaatgacc tgtgatgggt tgttaaactt 55380 ggcggttctt tcaagggcat caaggttata gtagttcctt ggcagtggta gtacttcgac 55440 gccatatggt ttcaaatact cacgatactc ccaaggttcg gaactgtaaa ccaagtctat 55500 tttagactca ataataaaac gaagatatcg gtctctatct tttttatact cctcaaccac 55560 ccaaactttg aatttccctt gttgcatgga gaccctcgat aaaataaaga agaagggtgg 55620 agaatgaact ccaccctcta accttagagt taatcgaaca tttcattgaa ggtatctaga 55680 acttcatcga ccaagtcgtc tttgtcctca tcaccctcgt aatgaattaa ttcgatatcg 55740 tgttcatcgg caagttcttc acaagctatt tcgtaacgcc tattcagttt ttcccaatta 55800 ccgcggttac gatgcttatc agtttctgtt ttatcccaat catcaccacg ctctttatga 55860 cgacgtaaca tggttttatg atctaaggta agtagaatag tgatatctgg aatcatgaaa 55920 tcaacatcag aaatgtcgat gatgtggtct tggtgcgcgc gggttgtagc aacataacgg 55980 tcgagcaaaa ctacgacatt atcatcctca ccatatgcct cgtttaaaga gatagatttc 56040 tctttgaaat tcagctctag atggtgtgat actttgtagc tcgggtcacc ctttgctaaa 56100 ccttcacgtg ccaatttacc atggccatca ttcgaaggga aaggttgtac aactacagtg 56160 taatcctctt cttcgaaagc ggctttgagt tttttgatta gggtggactt accggagtag 56220 tctacacctt ctacgctgat gattcgcatt gaacattacc taccttgatg atgacagaac 56280 gacccagttt cttgccgacc gtgcgctgaa tttctttgat tttactttcg ctcaacggtg 56340 agggtgcctg ttcgattgta aatacatacg gttgtttttt agcacgcggt ttttgcttac 56400 ggtgctcatt caacttatcg atgtcagttg taccatctgg atttagacca accacttcga 56460 tatccaaacc caagctgacc aggtaacaca taatcgtgtt cttagtacgg aaatcgttat 56520 tgaccaaaac caagtcgatt tcttttaatt ctttgcgcat gtattccgca ggggggattg 56580 tcactttccc attgcgtgaa atgatcgctt ccaacgcctg tgtaaccaat ggtgagataa 56640 ccccggttag ttctttgaat gggaactgct ccattccaac taaagcaata ccacgggatt 56700 catggttgat tggacgctgt gcattttttc ttagtgatgc tttgtacgcg aagatctttt 56760 ctagttcttc ttctgttggt ttgtttagat caccaacttc aacaccgttc tcttccatag 56820 ctaggcgaat accagcgtac agtgatgatt tacggaaacg gaatggtccg atacggaact 56880 ggtctttggc ctttagattg acaggatttt gagtatcctg actatattgt ttcaaaagca 56940 tatttagcga tggcattatg ctatttcctc atttctgatg taattgtaat tggaggtgtc 57000 taacttaaac cgtagcccgt cttcactacg gtatccagtg aaataaatgt tagacagatc 57060 ctcacacgaa tcaatactta ttagtgactt actaccctcg agtttcacta aatgggcccc 57120 cgccctcgaa ccttcttttt taggaaagat aggtttcggt attggccgaa taattaactt 57180 agcgccgtcg aagtagaacc cgtccgtcac ccatccggtg tacccaacta ggttttctcc 57240 tcttggtatc aattctgtga tgtatttttc ttcaccctca acaagatgtg ttgaaaaccg 57300 ttccgggtgc ttcaaaatct ggtacacaag ctcttcttca gaagaaccca tgaatcttcc 57360 acagatgata tatcggcaaa gtaaattatt gttgttttta acattaacga gactaacgtg 57420 gttaccgagt aaccttccgc agttatcgcc tctatcaacc caatccttta aatccttaac 57480 aggaaattta ccacggtccc agatatgcaa ttcatttcga gttgatagca acccaatcgg 57540 atatctgtag ccgtaatatt ctccttcagg tctctttaag agaggggaga taggtttaag 57600 taatttggca tcacctagcc gaatcttctt gatgaacgca ggtatagtga caaccttttg 57660 cctacgttca gcttgaacct caattaacgt gtcaccgagt gcaggggcgt ggtagaataa 57720 cccacatccc ttcaggatag catcaactga tttcgggtgt ttaatagcca tggttaaatc 57780 cttaatagcc aagagatgtt tatccggcta catttgcgat ctttcagcgt aatccaaaag 57840 tactttaatc gaccgcttga tggcaagagt catagcatct tccacatcca acatagcctt 57900 taattgttta gccgtgattc gcttatcctt ctgagatagt ccctcatctt tcattttctc 57960 atacaaatcg ttaatggcgt tagataatgc gcctccttct tttaggcgct tgctgtaacc 58020 gctaataaaa tcagataagg cttctttcac ctttttgtat tcttctttag ttagcgctgg 58080 aatagtcata tcgattgaat gttttgggta aaacttttta aatgggatat ccattatatc 58140 ctgaacctta ctggttggcg ttgcgccgaa cttaacggtt tgtgtaccgt cacggttcat 58200 atcgatacaa actaggacac ccgatggtaa tataaaggct gtaatatctt ttccgatata 58260 tagacttagt ttaccagcga gtatcagggc acgagcatca gtcacattga cttcccgtcg 58320 acttagcccg tctacttcca aagcagacat ccgtgttggg gaactaaagt cataactgat 58380 tatctctcgt cttgctgaac cttctaatgt tttaggttca tgtgcgaatt ttaaaatatg 58440 gtccaggtca accttaccct ttgaataaag aggaatagac catccgaagg ctttaatctc 58500 agcttcgttt aaaagtgggg tgtctgggag tttatcgtaa cgtcgcttaa acccctctaa 58560 accttgggaa taacgtttgt atttctcccc aagtttggcc attctctctg cgaaccaaga 58620 cttcatatcg tccatcagac cttcactggt aatgtaacga tgaccccatc gattggcaag 58680 ttcattcatt accaattcct ttgctggatt atctgattga gactctatgt cacagagtaa 58740 ctcatgatcc tcacaaagga tatcaaaatc actatctaag ctattcatta ctgatttctc 58800 ctattgtgtc tataggaaaa gccaaaaaaa acaggggacg gggacaaccc cgtccgttaa 58860 cctaagttaa caatacgaga acgaatctcg tttgccaaca ttaggtgtag agcagatacc 58920 tttttatcta cgatagtttt agcaaggtat tctgcacggt ctgctttttt ctttaagaat 58980 tccatcacgt ctacaagtgc attaccgtaa cggtagatag cttcttcaac aatgtggttt 59040 actttagttt ctagagttaa tgttttcatt ttaaaatttc cttggtgtta tcaaatttga 59100 gaggaccctc gtttggaggg tccttgtaaa ctagtgttta gtttacttcg tcgtcgtggc 59160 gagtggtttt ttctttaact agatttttga acagatgttc gtgtttagcc gagatctctt 59220 ttaactgtgc tttgaactga ccacgagtca gtgacatgaa tagtgcatac actgaatcca 59280 tcacaggcat gacggtttcg aagatagcca tttcatattc gcagatggca gccagtagtt 59340 ccggtgatag ctcgatgcta aggtcgaact ccatggtgtc tttgattttc aaagcgtagc 59400 ccaggttgtg gaaagagttt gtagctttgc agttaatttc cacataggag aatagtttct 59460 ctaccatctt gtaatcgtct tcatcgacca tcgcacccat gttaggcaat gccttgacaa 59520 agtcattttt ggcatttagt acagatttaa gatgtgcgat ttcttgtgcg tcgataacta 59580 gtttggttgt tagtttcatt atagatttcc tctttgacag ttaaagtatt tgtactacat 59640 tcactaagat aatatatatc tgaaaaaaat tttattgaga cttgagtaaa aaataaaaaa 59700 agagagaccg aagtctctca gttattatct attcttcgta gtccaacttg ccttcgacta 59760 gcgaattaat ccacaggcca aagacatcgt tttggaataa ctcgatgtct aactcgtccc 59820 actcatggtt aatgtgaaga cctagcaaag tatttatttc aacttcgata tctaccttgt 59880 ctaaatcaaa atcgtatgta aggggaacat agcgctcata attaacataa ctcattgcgg 59940 ccatgcgtct aagaagaaca tgctcaactt catgaaatgc agttttgtcg acagcgaata 60000 gggtttcacg aataccttcg atgaaatcca taatgctttt cgctgtgctt ttaatgcccg 60060 ctgttgcttc aaacaacgat gaatcagata accaatacat ccgagtgtct tcatgagaat 60120 accatgacag tgcatgattg acagcaatgt gaaagttttg acgcttagcg catgttagtc 60180 tatcactccg agcatataac tcgacgatct tttctgattt atctaggaaa ccccagacac 60240 gtaatgaact atctcctttg attaactcgc ctacaaacgg tgtgaggttt atttcgggaa 60300 tggtacgctt ctctttccag cttgagagga gtagtgggtc ttcgtcgttc ttttgtatct 60360 cggccaaacg acctgttgag aaaacaattt tctctatttg gtgttcacga acttgaatag 60420 ttggtagggt agctatactc aatttcattg tttaaaattc cttgttataa aaaagaaagg 60480 ggcgtttttc agccccaaga gagaacaccc cttatgcgtt aggggtaatg gtaaagaaag 60540 cctcgccatc acgttcgact gtgaacattg gcaccacttc tttcgtaggt ttatcaaaga 60600 cagcaaacga aatacgatta atcgttacca gcgtttcatc gtagatatag ttggtgtcgt 60660 ctatagtgac gcgattagta ccgtggtcgt aatcacggta atcgattaga aacgaactct 60720 ttgtcatgaa tgtggagaag ccatcgtaag gtaacccgtt acttgggaac accaagtgag 60780 tttccacagt ccgcaagttc tgataatctt cacgcccaaa caagtaaacg atgctgttaa 60840 tgcgagcttg gactttatcg ctaacagcca ccttgttctt gtagagacct gggttatcgt 60900 tgaaagcagg tgaccaaaca aaacaacaat cggtattttg tgtcatctgc tcaagttcgg 60960 ccaagtattt acgtagccaa attgcccggg tgatatcttc cattgttaac ccggtgtttg 61020 ctaatcctaa ccatcctttt gcgcgcttaa ctttgagggc tgtgccaagt tctggaataa 61080 gagtagggag gtctcgattg ccttttgttg acacgatcga ggaacgtaac cacgatttga 61140 tttcgtcact gtgattagat tcttcgatct cattagtaag aatctttttc gattcgttac 61200 caccacgcca aacattgatg tcgtcagaga aatcataagt cacgtcgaag ttaaaacaat 61260 ccaaaaacag ttgtgggcat tcggtgttga gtagtgtttt ctcttctggg gtaagaatat 61320 gcataataga catttaaagt ttccttttgt gtaattaatt cattaagata atatatatct 61380 gaatagggtt gggttgtacg atcgttattt ttaacttcgt agacttatat tttgaccaaa 61440 tagacagggt acgggggaaa gggggttata tgagattacc ctatatcctg ttatacccgt 61500 accatcttat ctgattaaga aagtacctta cccaacttag agtaattgag tttaggcaaa 61560 gtacctttct ccacatacac gttctcttct aaccacttat aaaccttagc ggtgtggggg 61620 ttaagaacag gtaaccctgc ccaaatttcg atctccaatg gaagagtttc ccaaggtttc 61680 ttacacttga gtgactctgc accgtaaagg tcgtagacta ctcgcttgat ataagggcga 61740 atgaatgacc cacaatcatt aacaagcaac caacgctcag cagcatctgt aaatttagtt 61800 tcgtcaccga ccgcgttatg taggtactgt ggtattgtcc acttccaacg catcgcatag 61860 cgcattttta ggatgacaac gaatctctcg aatttcttgt tttgtaatgc gtactgtaag 61920 atatcttggt acttgctcag ctgtagcaaa tccatttggt aatctgccat ttttaaaatt 61980 cctcttagtt ttgatgtact gtttgtacat taatgtaggc tttggtttca cggtaatgtt 62040 tgaccgagcc tattaaataa cccaagtcca aatactcctg gacctgttcc tgtctaatcg 62100 ctttccaatt acgactattt cggttttcac gccatgggtt atgcatcacg ggtttgccgt 62160 aagctttgac tcgaagatat cgaagatcgg gtatctcgat ataatagtag ccgttgctca 62220 ggtaagctgt tctccaaaca gtgggcatca ttggaaaatt gaactttgct agtgcataat 62280 ctgtcatttt caattcaact aattcatgct tgctgttagc taagactcta cggaatttac 62340 tctctgtgat tagacacatg tcttgttttt taggtctata cgacattacc ctattcctta 62400 tttatttacc agacgatgtt tcactctaaa cagtgtttga agtttgtcgt tgtctacttt 62460 attccaaagc tctggtggaa ttcttccgac cggggtcccc tcaaaatcta acttccctag 62520 gttgtatgat ttgtcaagat gctccgcttc ttcagataag acgacataag agtttgggcc 62580 gatgtaacca tcgacaaata aacgtttggt taaatcacca aacggactcc tagttagatt 62640 taaagttctt agagcattag actccttccc tttataacct gatacaggta ggaaccacca 62700 gtaatccaac cactcattac tattggttaa tttctcgtta tcataaaccc accctagcat 62760 cttaccagat agtgaaagaa aatgaacagc ttccggctta cttaagtcgt aatcaatttt 62820 ggatagtgtc caagagccac tgataacgtt aacaaataca gcaatgggtc ccgggagata 62880 ccaaaggtgt tgtttggaac gttcagcgaa agtctttcca ctgtagattg ggtgaggttt 62940 agttacagtg tgccgtttct tccaaagttt cttaaactcc tcccagtgtc tttttggacg 63000 atacattatt ccaccccttc taaaaggacc agccaatcca catcgtactc aaacactgca 63060 ccgacagatg aaccttctgt catcttcacg tagatggggt aacgactacc cggatacaac 63120 ccacgtgttg cctcattcaa acgatggacg acaccgatgt gatctgtgcc tttcacactc 63180 acacttttac caacgttggt ttcaaaccat aaacgctgcg caggagacgg accaccttct 63240 tcctcgccac cctttaggaa atcaaccacg ccttccacat tacccgtttc ttttatagcc 63300 gccaaacaaa ttccggctgt tgctgaatca atcatttctt tactccttcc atagctgtgt 63360 tgataaggca cttaaggtta agtgcgcatt cgactgtagc ttctttgaca aattcctcta 63420 ccgtctttcc tgattttgtt gccgcctgtg tgatggcggt aaattcttct tcgctaaaat 63480 caacaagata atctttgtta gccatcacac actcgtagtt tttattagcc acttcactta 63540 cccctttgta ccttaccttt tagtttgtaa agtactatca ctgtgattac gtacaatact 63600 gttgctgttc caataacagt acttttattt tctaacccac caaagaactc gactatctcg 63660 ggattgtgtg cataaatctg aaccgagata aagtatataa tcgatggtgg gtatatgaag 63720 aagggattca aattacttta ccttaatgtg ttttgtttct ttcaaccact tatcaagttt 63780 ctcttcatcc catctcggcg atttaccgat gaataaagtt ggcttcataa agttgattgt 63840 tcgaatacgc tcaaatgtct ttctagaaat agaaaggttt ttacagacac catttatagt 63900 cagcagtttc attaccaccc tcgtcttttc ttccttgcct tccgagcacc cttacctcgc 63960 gacactcggt tatcatgggg gcgcggcaat gtagtcaact gattcagagg gtgtgggtta 64020 accacatcat ctaaactgat aataccattg tcttgaatgt tctgaccaat gttacaaagg 64080 ttacccgagt atttttcatt ggtctccaat atcactctta atacttctgg actaagagca 64140 gccaacccgc taccaattac accaacctta atcatcttaa acctctacgt tgatataaat 64200 gtttcttact aagatcactt tgttggatag caggcttaaa taatctcccg cgtagataac 64260 gttgatcttc tctgtgacct aatacagatt gtatcgctga ttgcagagtt gatttaccat 64320 gatcaacatg cccgatagtg ccaacattaa cccgatgatt taatgccaat tgtggtcgtg 64380 taaacattgt cttgtatgct ctgaccttgc acttagtggt gagagtttct ttagacataa 64440 cccaactcct cgatgtcttc tttgattagt tcttccattt ctggagccgt cattgtttcg 64500 accttttcac gaatcaactt catctcttcc ttgtagaact taaagtatag cggtggtaat 64560 ttagctgtac cattcttgcc aaatttacta cggatgtgtt ccaagccatg tagaagtgct 64620 tcctcactag acttaccgag ttttgtcaag ccgtataagt aacttcgcag gtagtacttc 64680 ttaaggtctg gtcgacctct atcagccaca gcaattatct cagcaaatag attataatac 64740 ccacctaccc acgaagcacg atgcgagagt gctccttgtg aagcccaggt gtatttccat 64800 cgattctcgt taaactcacc taggaacccc aatgtagtaa actcatccga gacaagatac 64860 ttggctgcac gatgatggtg gtcttcacga aaaacagtaa acatgtcatg cgcgtaacct 64920 gacacaatgg ctattgggat ccatccatct ttccctaacg cttcacagat gtggattgcg 64980 ttgtctacga cgtcgtcagc gtggttgatg aggtgagcag catcgttctt tgtgtagtaa 65040 cctacgaaat gctctcttac catagcgcgg aattcttcgt atttcttctt atccatctta 65100 cttattccca atcccaaaca tcttttactt ttacgttttg tggtttagtt aaggttctat 65160 ttagaacctc gtcaattgtt aagccaagaa cttggtgctc tgcaaaatca accgcttcat 65220 tatacggcat cttttctgag tacttgacaa cactctcttg ataaagccta ttgattgcgc 65280 caccaagggt cttatgtgga atgatagagt tccagtcata cttcttaact ctggaccatt 65340 cccaaatgtt tttgcagcgc atgtatttct tatcagggtg ccatttgacg cccttagcaa 65400 aaacgacctg attgatgttt ctaaatttgt cagtgtgtaa agtagcttct ttcatgagtt 65460 ctaatggtaa aactataatt agattaccgt ctttgccatg gtcccaattc atatcctcca 65520 gcatcttaaa aagtgctttt ggtttaatcc cgcaaaaggt agcggtggga ttgatgatat 65580 cgttatcgtt aaaagatatc cgacatggca tagctgagta aacaacgctc attataaatt 65640 tcctctttct tatctaaatt aagatgttgg taattccact actataacat ctacctgttt 65700 tacctttgaa tacattagcg ataaaaaaag aagaggggta gtaggaaatc ctactaccct 65760 agtcttcaag ctttctttga ctcaatacgt gaaacagctt cacgacttgt ttcaggtaga 65820 acaaagtaca aacacatgtg agcatttgct tcttcattag tgtaaccagc tgtatcttgt 65880 ttaagaacag gagttataat ggaagaggca taatgactaa tgcttggaga atctacgatt 65940 ttgacatctt tgtttttagc atcatgtggt aacaactccc actctttagg ggtaatcacg 66000 taataacgct caaacactga ggccactatt ttcttaatga agtccgatgg atcatcacaa 66060 agcacaaatg cagcatggca aatcttagac aaggcactgt aagcagcagc actgacacga 66120 atctttcgac ccttagttaa tagacgaatg atttcatcta agacaggtga gtctggagaa 66180 tgacgcaaat aatcgcgcca acgtgacatg tcattgttct tgactttagt gatgttgaca 66240 gttaaggtgc ttttatcgta gtagtcacga atacgtgttt ccacgtcttc taatcctacc 66300 actatgtcac cagttgcagt ctcaaaagaa taaggttgca aaacaatagt caacagttga 66360 ttgagtcgac gagcacccaa atcctcttct gcctgattta actcgtatgc cattgaagcc 66420 actgcggtaa tggcctcatc tgtcaatgtc aagttaatac catcagtccc tagaagctgc 66480 tgtatggcga gcaatggtga cttggctgac ttagtaagga tatcctccaa atgcttagca 66540 gagagcgaat gaaggcgtat ttgaataggt aaacgcccac gcatctccga gataagagaa 66600 gattcaccaa cgttagcaaa agcacccgcc gcaatgaaca aaatgttact ggtgttcata 66660 cggcccatac ctttctctag accagagtta ttttggtcta ggtcaatgtt accaccttca 66720 atcaccttca gtagctcgta ttgaacctcc acaccattta ctttaccacc gccttgatca 66780 accagtttat cgatttcatc aataaacacc accccgtagt tttcagctaa tgccaacggt 66840 gtgcggattt cagcaggtag gttaaccgtt ttatcgtcag agagtaaagc aaggatgtat 66900 ttatcgatgt cgttttcgta ctcgtcaaaa ttaaacggct cgctattatc gagtccttca 66960 aaattactta gagccttacg aatccactca ttagtttgga agaagccacc ttcatcccaa 67020 gtcttaactt tctttaagga aagcttggtt tttccttcgg ctacttccgc aataacttta 67080 tcaacgatac cttgtagctc tttcttagag gaagctttgg tgaaacttga cacaatgctt 67140 ttatcaccgc cccaaaagaa cataaccaga cgaaagattt gtcgtatggt taacccttcc 67200 tttatcttgc cgtaattagc cacgcaccca tgtgtagtca tagagtgagg tattggtatt 67260 ttgaccatgg gtggtaatac cataacatcg tccaaggttt tgttatcctt gatcgctgca 67320 cggattaatt tctcatgttc accaatggct ttccttacaa caccaccatt atggttcttt 67380 ctcaggactg taaacaagtt acgaagaatc ttattttcaa atcctggttt aaactcaata 67440 ctggcagagt tttccaattt gtagttttca actacctttg gatgaatttt ttctgcttcc 67500 tttaatagct gtttaaggaa atcagttacg ttaccaccaa cataaccacg tgaagtgaat 67560 gaggtcgctt ctgtttgcac aaaggggaag tcacataacg ctgccacctg tctagctagt 67620 tctgttttag ccgtaccaga tggaccctta attaaaacat tacgaaccgg aacccacttt 67680 ttatctttgg ctggaagctg ctgtctccgc caacgatcac gaaatgagac ggcgatagaa 67740 gccttagctt cttcttgtcc tatgatagtt ttatcaagga acgccacaat ctctgaaggt 67800 tttagattcc gcatatttat atatcccttg ctttttctaa ttgtgtcata ctaatgtctc 67860 tacggttaaa aataaaagta ggtgtatgac ctaagccata cacctacaat tactacacac 67920 gaatagcttc acgcaattcg ttcttcacat cttccagcga agggagttct aacttggcaa 67980 cgtagtagaa tttcttctgg ggccaacgaa cttccatacc aaccactagg ccattttcgt 68040 agtagtgtgt tacaatagca tcaccactgt taggaccagc gccagcttca cgttttgccg 68100 cttctttgac tgctgtttta aactcagctt cgctcactag gcgataattt ggagctgcaa 68160 tcaagtccaa tttagtttcg agtagcgcaa ctcgttcaag tacttcatca cgtaggcgac 68220 cgatgacgat gttagctaga gataactcgt tatctttatc gattaacagt tcctctgctg 68280 tctttgtcac cttctcgatt gtgtcggttg cacttttaac ttcttcggca acgtgctcta 68340 ctttttcaac cgcagtttcg actttatcaa cgacattgtt gatggcttct gaacctttgg 68400 ttaatttact agctaattta tcaaaccagc ccatgacata ctccttagtt aactattatt 68460 agtcataaaa aaggaagcta aggagacaga gtatttttct gtctccttat taacctgtca 68520 taggacaagg cactataact cttcccttaa atcactttcc tgtttcattt ccaaataact 68580 cctttgtgat aagttaacct agagtgtttt tagcgcagta atagttgtag ttaacactca 68640 tgacattctc ttagacgttc aagtatcact tctttatact cgtctttgag attggtagat 68700 aggtaaagtt tccaataccc tctttgttca tggttaccaa gtacgaaagc aacgagttgc 68760 tccgacaaca aaggattgaa ctcaatgtct ttgtaaacta gctccaacgc aatagctaac 68820 aaatcattag ctaagcgctc atcaacatca ctccgttcca aaagtgaggt tatgacggca 68880 gcttgggttt ttggttcaaa gttactcatg acacttagat ggtaaccttg tggagaatca 68940 atcactttca gtaaggcatc catatctgga atcttaacga ttggattgta ctctgattcc 69000 ccttcccaca aatcgaaact tgtgaagtct cgattcaacc ctagattaac gattacattg 69060 gcccccactg tgacgtcgtc tgggatgttt atttctcccc aacgctcctc cgggaggttg 69120 cttaatagta acgaagcgac acgtggatat tttgagtaat cactcattag tttttgtatt 69180 gcttcctcat ctagtaccaa agcatcgtag tagtaatgtg gtagtcgatt cggtaacaaa 69240 atcgccagct ctgccaagtt agtggcagaa gtgatacgag tcaacatctt tgttatttca 69300 aacaaccgat acggcgattc atctttaatg cgttttagca cttgatgaaa tatttcgggt 69360 gtaactcgat gaagacgtag tttgtggtaa tcttccgtaa ttacgtcggc caacttctcc 69420 ttagttgcca gtatgcgctc ccatcggttt atcaagacac tggatttatc accatagtgt 69480 tcaatcaaaa cggaatgtgg gattgccttg ttgtgaaaac acatagtcaa attacgtgtg 69540 ctaatatcac tcatcttttt cggcaaatct tgaatagtaa gattcttgtt aaaacgataa 69600 gtgttctcaa acccaaataa tctgatcgaa cgttccactg gaatatctaa agtgatgttc 69660 acgaaagccc gtaaagaaag ttttaattcc ttcactaaag caacgttagc ttcattaacg 69720 cacagcataa attttttgct cccctacaga aacaagttca aaaagacgaa taatgtcctc 69780 agggtcgctt atgtttaaaa actctatgct ttcacgtcga gcagctccct ttagacaacg 69840 gtactcgtta gtatcatcgt ttatgtctcc agcatacacc accacatcgg atggctcttt 69900 aaggtctggg cctaacacag cacaaatgtg tgcacccagt ctttcgcggt tgataaagtc 69960 tttactaacc attgattcta acacgtcaga gtacggacgt ttatagaagt ctacaacatc 70020 ttccattacg taatcttcga ttatgaatgg aattcgatcg agggtagctg gataagcttc 70080 gagctcaata tcctcacctt caatcaaagc acgctccaca gcggcgtagg ttgcttcata 70140 accaccacgt ctacctaaca caatacgaat gtcgtgttgc gggataaggt aagcagtgat 70200 accgaatagc agtctttgca ggtctgatgg aatgtgggtg ttaccaacaa gtgttataat 70260 catggtgatt ctccttagta gatctgccac cacattgata atatataact gtttaattat 70320 caaatgtatg acattgtatt gattgttaga tctagccagg tgacgtcatt tttataatat 70380 tttctaacgg gtcgtgtact acattaagtg taggtatgcc caaagactcg gcatatcgta 70440 ctcccattgc tgtccctccc tttacttttt tagacataca accatatacc actaagtcaa 70500 cgtggtcatc taaatcgacg ccagcaataa tacttagatt tctacaatga agagggtaat 70560 ggtcttcctt tagtgcatcc ggataactgt gtaactcacg aactatcctt ctgcgttctt 70620 cttccaactc cgggtttcca tataggcaat actcgtagtc gtaagaactt ctggtgagtt 70680 gccttggcgg ataaatttca atatccactt tccgcttctc tataatagct tgctctaaaa 70740 caacacttac tactttatct ggcccctttt gacagcgacc tgaccgaatc aggtgcatgt 70800 atgaccaatg agttactaaa ccaaatagta atctgttata tcggatttcc gtttctcttg 70860 atccaataac ggcaatcttc ataaccacct cggaatatgt tattattctc ccattatatt 70920 aaaagtgttt agcgttaaaa aataagtaag ggacgcagca agcgctgcgt ccaatacaat 70980 caccggggtg attatgcgtc gtctgatgga tccatgtcga cgttctcttg tgtaaagcct 71040 tccatagatg gagtagcgat acgagtacga agagcagcat ctacagcaaa cgtaacttca 71100 ccagtgtaag ccaagttgcc tgcaacagca gtaactttga tttggcttgc agttggcatt 71160 tcgaacgtgt aatcagtttc gttaaatgcg aaaccgtatt tacgttgtac ttccgcgatg 71220 aagtcagcga caacaagttg gccttgttcg tcgattgctt cgatttcacg gatgttgttc 71280 ttagaggcag caacgattgc agagaatacg tttgatacat ccatacggtc aaagtagaat 71340 gtaacaaagt caccaactac ttcagaaggc tcaaccagaa ggtcgatgtc tacagaagag 71400 tttttaccag atgcgtgacc tgatagaaca gttaggtttt gaatatcaac gtcagcaggg 71460 ccgtagcctt tgttgttgtc gttgttaatc aggcccaaaa gcagaagctt aggagccaac 71520 gcgaagttcg gagtataagt agccatactt ctctatttcc tttttctagg gattcaaaat 71580 ttagtcggta ttagaaatgg cagttcttta ctgccattgg ctattactca actacagacg 71640 cagctgcgat tggttcgtaa acgaaaccgt tcagttcagt aactgtgatt tcttcgctga 71700 agtggcgagg catcacgtac tcaactgctg gttgccacac gtaagacgtg atagcaaatt 71760 gcagtttgta acggttaagt tcagcgtcga aaacgcgtga agcttgaaca gagtcagcgc 71820 cttggtcaag gtcaactttc tgacgaacag cggcagcttt aagagcagta accgcagcag 71880 caggagaagt ctcagcatcc cataggtctg gttcgtacca tgtgaagtca ccagcagctt 71940 cgtccatgtc gacgatgaag cttagttgca gacggaagta gtctacatct acgaagtcag 72000 atggaaccgg agtgttcaca agacggacgc cagttttacc agtagcagcg tcaagaacag 72060 acaggttaga cagtgtagtg ctcgctagtg tcagcggagt accaactgaa gattggttgt 72120 agtggttcac catgttcagc aactgctgac ggtgtgacgc acgagggtta agaatataag 72180 cactcatatt cacatttcct tagttgattg tggatggaca cagtgtgttc atataaagaa 72240 atgaaaaaag gacctcggct cgaaagccaa agcccttgct acgcctacat cggtgagtaa 72300 aaaaattatt ctacacgttt ccaacggtat tctggatcat ccacattcgc caaataacct 72360 ttgcgtttcc aaatgatcat gtaagtttta atgccagttg tcatctcatc acgccttact 72420 tctttaacga attcaccctt tagcggtgag tcttccaaag taatctccca tgagtcggaa 72480 acctttcttg ccaaccctgt gttgtaagtc tcagagccag ggtttaagca aatgaccttt 72540 aagtcattag cctgcaccca ttcacttaac cattcgaaac ttgtagcgat gggcatacgc 72600 attaaatcat aaacatcacc gcttagaatc aacggtgtgt cctgttccca tcgtccccag 72660 atatcaccat tagggtcata atcagggtct gatgtgtaca agaacccatt aatagggtaa 72720 gggttaattg gtgtaagact ataatagcct ttaaacttaa ccacatcgaa tccagtaatt 72780 agattaatgg gtaaagtgtt gaatagagaa tcgaagatgt gtaatttggt tctaccgtgg 72840 tacagataag aatcttcaag tgcttctacc caccattgcc cttcgacaga aatcaaacgg 72900 atatgtgtat ttaaatcgac accgtacaac ttagctgttt ctgtgaagaa acggctggta 72960 agtctcggtt tagtttcggc ctggtcaaac caatcaatct taccacgccg taaggataga 73020 aaggtagtgc caaataaaat gtttaaatcg attcggttgt atgtcacttc atgatcagtt 73080 ccatctgtgt ggtagagtgt ggctgatgta ttacccaaac tgccattaat gagttggatg 73140 ttctccaagt gatctatagc atcaagtttg acgtagctgg aagaagcaga ttcttttaat 73200 agcgtagcta gtacgcttat tttatctaga gtaagattga acatatggtt tctctcaaca 73260 aaaaaaatag gagagatttc tctctcctat atgtctttac aatcggcgca gtgctatata 73320 cggaatatgt ttcacataat ctattaatag actgaggcct tcgaatggcg gggttgcgtg 73380 caataacttc agtaaacgta tcttgaaatc aaaggaggat tggtaaggtc ctggctcttt 73440 gtttgcgacg tagttataat ggtacattgc gaaattctca acagagttaa ggaactcttt 73500 tttatcttcc gcccggaact catccgcgta attaaagttt cttagataaa caacacactc 73560 tggtggttgg atacctacca ctctatcacg tgggtttttt ggtgttagtt cagataatcc 73620 atcattgaac ttactcacca agaacggttc actcacttcc acaacttcta cgtcttcacc 73680 aaaacaagat ggattcatag caatctcctt agggaaaata ccagtggttt tgtttttact 73740 aaagaaacca cctaactcgc gtttaattac atatgttact ctacaaccta atttattctt 73800 aattgacaat ttaatttttc ctcttttgaa attaactatt ttggtagggt gtcttattta 73860 tcccaagttg agtcttttag cccattctct tcccgagtac ggtcctcgta catcttgctg 73920 gcaagggtcg ctaaatcggt tctggactta caggcattca ccttctcttc taccaaattt 73980 agagggaata atttactccc tttcgctgag gattttttag tcaactctat caagtctttc 74040 tttgccttat ctaaatcaaa catatacaat attccattag cgataatatc actacgataa 74100 tatatatctg aattaaattt tactcaacct tataaatcaa ttggtagcga ttcgaccatc 74160 ataccatctt ccacccaaga tttagcaact tcagttaaca cctcaccaaa ccgaacttct 74220 tcgacaagtt tgcagtgttt aaagttaacg tatggtttat tatcaccgtc accatcatct 74280 agagggtgat accatccaac tggtgagaag ttacatttag cgaacagagc tatggcttta 74340 aagttactag gatggcaaca agcactatct acacgattag aatttataag ggcattgatg 74400 tgctctgtca tgtggccatt acgtcgagct tctgtggtcg tatagcagaa aataatacgg 74460 cgatttagta accaaatacc tgtaactatt aactcatcct cgatgccaaa ttccacttcg 74520 acacctgggt agcgttcatc aagtcgtcta gccaagtctt ttatctcttt ggctttgggt 74580 gggagggaaa cgtaatacat ttcaagaatc cttatttatt ttttagaacc aagttcacat 74640 tttccaaaag tttatttttg gcatagttga tagttttaga ctcaacgtac tcttctaagt 74700 tttcaccgag atactttatt gtttcagatt tcaatagtgc ctctttggtg ttaggaatgt 74760 gcgggttgat tctctcctct gacacatacc ccacaagctt cttaaatagc ttgtaaacac 74820 cgtaagtcct tttagctagg ttgatgtact tcttaggacc ataaaccatt atagcttgtt 74880 taacgaccca ccttgcagca tcccttgcag tcaattgact ctctgagatc aatctgcctt 74940 cgtagatacc actaatcgta aacacagcat accaacgaac cccgctaagt tttttactct 75000 ttggtttaaa ctcacacagt tctatttcta gatcttcata gtccaagtca gtgttgatta 75060 acgttattcg ttttctatca tcgagtaacg ggagccgatg ctgctctatt atattccata 75120 gtagaagtgt aagttgattg gagaagtctg tatcgcatcc tggtctttta ggataacata 75180 acccatcaga atcagagaaa gtcaattctt cgatcttctt agagatagtg cttttaatgt 75240 cggagtcgga ggtgtttatc tgaaataaat aatacttcat agccaccatt aaacttttcg 75300 ctatcagctc tgtggcgaaa ataccggata agccagagta acgtcctata agacggcaat 75360 tctgattaac cagttgtatg gtttcttttc tcaactgagt aacgtccacc aatcgtgcct 75420 gtttggcctt gtagtatgtt tgctctgcca tgttcttatc caagtttagt taagctataa 75480 aaagtccaag atgcgttaaa aataaaaggg gaacacccct tgcattagca agaagtgtcc 75540 tcaatcagtt ttagaatttc tttatcgata tcgacatcgt gcctatcgat tttgctaggg 75600 gtgtaaatac gatgtagttc ttcccttaac tcttcaccag tcatctcacc gtaaacttcc 75660 gcttggtcta cagtagtgaa tttagataag aataaacgac caatattagt cgagttaatc 75720 ttcttaccag cgtgatgttc tacaatagta cttatcttca tttcttctta cctttacgac 75780 gacgtcttct ttttcttgca ttcccactcg ttggtttctt ctcccttatg aataatggag 75840 gtaattccaa caactcaaaa cgccagaaat aatgtccgac agcaatagag tcaatagagt 75900 gctcgtcaag taaagttaga tcaatctctg tactttcccc aaatagagat aagaccgctt 75960 gtctaacttc ttctttacca gtacctatat gatccacgcc gacgtaatgt ttaactgaaa 76020 ttggatttat accataaacc tttgtagtga gtgtcaggct acgtacagcg tcatgaatca 76080 tagtttgtag ctctacacca gattcatacg ccgacatctt tccccttcta aagaatggtg 76140 tttcagtgat aaaaaacgta ggttgggcaa attcaatcac ctcaatcatt tgtttttgta 76200 tctcttccat tctccagcga cgaccaccat caatcaaaaa aagactgtct tcaacctttg 76260 ggttttttac gccaacggta tctgaccaga cgacaacagg taacttatta aagtcttcta 76320 tgtctacttc tagtatggaa agacccagtg tcacagtgcc tgggtcacat gccataattc 76380 taattctgtt atcaggtgga ggcggcggta gactaaccat tcgatgtgcg gagtttcatc 76440 ggtttagttt ggcccacttc aacttcataa gccacgcgtt ggttagtttg agctaagtta 76500 tggtaacagc taatgaagat acccggctgt aaaccaatca cctcgtcgaa cacgatttgt 76560 gaaccgtcac cttttggaac ttggacagtt ttatcaacac ctgtacagag gatgatttca 76620 gacatcactg cttttagtgg gttaccgcgc atgactctag ctacattaat gtactcttgt 76680 gtgtcgaatt cattgaattc aacgttgcgc atgactgtac tgtgtacgta ctcaccgtcg 76740 ggcaaagtcg atacaaggtt actaccatct tcttcgagag atagcgaagg gacacgtagt 76800 ggttttggat aaagatcttg gtcggtgtat tcgaactctt tagttgagct cttaccatca 76860 acaaccgtag tcttatacaa aatcgccttc tgggtttgct taggaagacg tttgcagtag 76920 taagcaaaat aacgaatacc accatactgt acttcgcgac gtagaccata gtttgcacgt 76980 tgtgcctcgg tcagatcatt atcgagttcc cggataacca tgggtactag caagaatggg 77040 gcagaatcgg ttgggttgtg tgcaactggt acggtccaca tcaactcatc agaatcagtt 77100 tgtccctcat gacccttttg accgacgact aagtattcaa gaagcggtcg ttggtccggt 77160 gttggtttca catctttaag aatgtttatg ttctcattga tggtagattt ttcttcatat 77220 tcgatgggtg cacctgtaat aagactagcc tgaatcttca tatacgataa agaaggcgtt 77280 gtcaatgcac catcaaaaac tgactgatcg ctcattgcga aaactcctta atggtttaat 77340 cgagtggaaa ctcgaaacta cctaaacttc taattcttat ccgtgaagcc aatgtgttat 77400 tgggttcggg atccgtccca cccaccatct ttgcgatagc gcttgagtcg taaataacac 77460 gtgtaaagat ttcttcgtta accacactgt tggcataaat agccgtatct accttgactc 77520 gctggatggc gttgtcatag gccgtggttt ttaacatatc aaagccgtct actttaactt 77580 ttgctccgag ctcgatagcg ttaactacta accccgattc agtaaaagat tgaagcttcg 77640 attccgattc cgagccaatg tgttgcacca aagccacagt tggttcagtc gacaatttat 77700 cagagctggt aaattgtgta gagaactgta tagagtaact cgacaactta ctaaataacc 77760 caactaagtt actttgtata tcatcgaaac ctatcacatt atcagggtcg taatcggttg 77820 ttaatttaag aaggtctttg gttaaatccc gccacatcgt atcgctgtat ttgctaggat 77880 caataccaag ctcgtacagg aactctgtgt agtccttgtt caccaactgg tgtgttagtg 77940 tatggtcacg ataagtgtaa ttaaataacc actcaacctc acgacgtgtt ctatcatcac 78000 gttgactacc taaataacgc tcacgacgtg ttttgattgc gattcgacga gtaacacgat 78060 cataaaaatc atttctgttg taaataacag aagtatcccc gtccgtggtc tcattaaaga 78120 aatcgatgta agtgtctaag ttcagagtat gtggggtgat tagaccctta gtgaattcct 78180 ccttagtata ccacacccct tcttcagtac tgaccacgtt aaagatagga atccacttca 78240 gctccaagcc atgataacct ttataatagg catagagata aagtgcgaat gattgtagcg 78300 gtgtcacacg gaaagagtta ccagattgtg gatcaataac atcggcattg ttccgcatta 78360 aatcttttgc agaatgatag gcccattcat taatcacacg agtcagtgtc ttctctgaat 78420 taaatgaact ggggtcgata ccagaaactt ccagtaactt ggttggcatt gaacctgtac 78480 cagaacgaat caataaatca ccggaagtct gaatatactc gtctatcatt cttccatgtt 78540 ctttacccgc atcgtattct ttaccaatca cttcttctat tggtaacgtg tcgatatctc 78600 ggccacggga acgttcttta aagttaactg gttctttaac acctatgggg tgtttgtaca 78660 atccaccact tttaacctcg gtgtaattct cagcaagcaa gaacttatcc agagggatat 78720 ctcgcttagt caagagattc tcgactaaga aatcaaaagt gtcctgttta cccgcatgtc 78780 tttcaatgta ccggatatta cggtacaaga ataacatttg ttcaatagtt aaataaggaa 78840 catactcgtg gagattttgg tgtgagcgta aaaactctgt gatgtggtac gagtgggttt 78900 cgcttgtatg gatggcacgt aatcgaagtt ctttgatttt acctggaagt agtgcataaa 78960 tgcggcctat gtgatccgcc acactaaagt tatatgcagc attccacgac tccatcacat 79020 attggtgatg gtatgccttt atccacttct ctatgttaag aatgagtgtg gcttcctggg 79080 cctctacaag gtctttgtta tagcttatga tagaaccatc ttccagtggc acagttattt 79140 ctggcggtac tgggttgaaa acaccctcta tatataacgg cataaaagga tatctatcgt 79200 gaatcttttc cctgttttct gggtctcgat agaaagtgta tgttttctta tgattcttaa 79260 gcatatcttt cgttaagacg acggtttcac ctgtgtctaa cgattcaatt tcaactgtct 79320 cgtcgatgcc ttcaagatat tccccgttga ggtgtttaaa ataacgccac tcacttttta 79380 tatcgggaat agtctgacca agctctttca atggctggtt catggcaaac gccgaccaaa 79440 tagatttaaa ggttatgctt cgcgctaacc gcataacctg attattgtaa atcattagga 79500 gtcctcatga tatcagaatt ggatccacta gctgaggtgt tttattctaa actcacctca 79560 ccgacagaac gacaaaggca ttctagtggt gatgaacaaa ccccatcacg atgggaatta 79620 agcccaatca accgagccct gatgcaacgt cgtctagacg ctgagcgaat tttcgacacc 79680 ttaccagaca tggagaccat cattagtgtg gccgtgtcta gtatgctctg tacaaaggac 79740 ctggtaactt caacattagt ctataactgc cctgttccgg agaatgaaat cccgctgtca 79800 gttaaagaga atatgttaga tgttttgagg gaatatttca gcaatgagct aaaactccct 79860 caaaaacttt acgagtggtt gtacgaggct atgtcagtag ctggagcagt accattacta 79920 atcctacctg aatcatcttt tgataagatg tttcaactac gtcgtgaagg catcgcgaaa 79980 tcaacaacgc tacctggtct atcatcttca ttaaagtctt accttgataa ccaagaaggt 80040 tactggggag acccagaagg aagaccaaga ctttataccg aatcgtatca gaaaccggaa 80100 cgtggtactg gtgccagaga aatcgaaatc ggtgttgaag aaagcaaact cgaaggtaag 80160 attatactaa ctgataacat tgactttatg aaagtcaaga agaatcagcg tgtggccttg 80220 caacgcgaat ctttccgcga aaaggcatta agtggcctga atagcttggc atcgtcatat 80280 aaagaccctg gcgacgttaa taaagataag acggctgctt ctatgggtaa acgcatcaac 80340 ccaacatacg aagataagcc gaactcagca ccgcacttaa ccataccaac cgctaaagaa 80400 gcaggtcgtt ctaaaacgca tccttctttg caaccatatc catctgaagc agtcatccca 80460 gtaaccattc cgggtaatga actagatcct atcggatacc ttatctctca cgatatgagt 80520 ggtaacccac tttcgctacg tagtgtcggt agcttagaca atgctctatt tactaacacc 80580 tcgggcggct cagatttgat atcttcttct gcacgtgcac ttggtttaac tgacaatgaa 80640 gtagcaccgc cgattaagaa aatcatgtct aagtatggtg aaatggtaga gaagaagttc 80700 ttagcttcac tggaaaatgg tatgttgggt gaaggcattg cactaggtaa gaacgaagag 80760 ttctatcgtg tgatgtatgc acgccatctg gccaaacgtg acacagcggt cgtctattgc 80820 ccggctgaac aattggcata tctggctgtt gacttcgact ccaatggtat cggtcgtagt 80880 ttaattgatc gttctaaagt tattagtaca gtgcgtatgg tgcatttgtt tgctactatg 80940 aataccatgg tacaaaactc tgcacgaaac attcaatatg aaatcactgt tcctgaggaa 81000 gaacgcgatc caaaaacagc aattgctttg gcaaagagtg acatcgtacg ttcgcataat 81060 tcattccagc cagtttgggg tgatgtagat gacgtttatg cacaaacagc caatgctggc 81120 atcgtcttta aagttattgg taacgaattc tacccaactg ccaatattga acaaaccgac 81180 atcacaccag atttcaaagt ccctgataag gaactcgatg aaaactttgt gcgtcgcatc 81240 tgtcaattag cacgagtgga ccctgacctc atccttcaac ctgagaactt ggaatttgct 81300 tcgcagattt attccaagtc gttaatctca actaaacaaa ttatcatgaa gcagcaaggt 81360 attaacaaga cggtaactaa ccttgttagt aactatacac tgtcttcagg tattttgtta 81420 gataagttgg ttgaggccat taaaggttca gatggttatg actcagaaca cccagaacta 81480 atcccacgtt atgtacgttt gctgctagaa tacttgaatg tgcaaatccc accaccagat 81540 acatctttta ccaaatctca gatggaacag tatgatgaga agatgactat cgtagataag 81600 attcttgaag atactatcac tgacgacgta gcggatgctg ttggtgtaga tggtactaaa 81660 ttacgtgcca tcattaaaag ctggtatagc attcagtggt tgcgtaacaa cggtgtggaa 81720 acagatttgg ttgatacaat cttaactgag acagaccatg cagcgatggt taaagatatc 81780 acagacagac actccaccat tggtaaatta attgccatgg ttaacaagcg tctggaaggt 81840 aaacttgaaa ctattgctaa gaactacggt acaccggatg acggtggtgg ttttgggggt 81900 gacatggatg gtgatggttt atctgatgat atcggtgggg atttgggtgg agacgacgat 81960 attctatccg acgacttaga tattgacggt gacactgata atgatgccga gggtcctgaa 82020 gaaatcgact tggattctga tactgattct actgacgaag tagaagaaga tgaggatgaa 82080 gagaaaggac ctgaagaaat cgacctcgac taaaaaaata aagaaaaaaa tagggactcg 82140 caagagtccc tataattctt tttttacttt tctacattaa aacgagtaac gtttgttaac 82200 gtagaacttg gcagagctag ctttctctga gataatcatc gcagcattgc cagcagcagt 82260 atcagccaga atgacaggca tgataccatg atcactccaa gcatcgccga atacagtatc 82320 gcgaatttcc aatgcggcgg tagccacagt atcaagttca ggatgatact catcattaat 82380 gcgaagtagt ttagcatcgc ctgctgcttc tacagagcga cagaaagccc ctgttgattt 82440 cacagcgagt gatagagtgg aaatttcaat acaaccgtct ttatcacttt tatcgatagc 82500 aatcaacgaa cgcaccatgc cattgtatac cgcacggaac tgtgattcga taccgttatc 82560 aaatacatct gggttagaga acattgtttg tgtttcttcc cattcgacca gtgcatcatt 82620 tgtgacgtag tccatcttaa cacgagagta aagattggct gtaatctcaa gtgctgctac 82680 aagacggtat ttaatcactt cacagaaacg aatagtagat ggattgtcag agttacgaag 82740 atcggccacc atctgcatca tctgttgaag tggttcacca ccacgattga gattaagagc 82800 atcttcaatc tctgggttgg acaggaactt acgacgtttc tgaataacgc ctacttctaa 82860 agaatcatct ggtgtgcagc aaacaaaatc ttcgaagtta tcgaagatag gaagctcttt 82920 acgaacttca tgtgctggac gtgagatgaa ttcgatacga cgactttcga ctttaggttt 82980 gtcgtaagaa ggttcgaccg acgataagct atgttcttcg aatgtttcca cgagaactcc 83040 tttcactagt ttgaatttac gtgggtcgaa tacactaggt ttccctttga attctttagc 83100 caccacttcc acttcttctt ccacttcgat acgatcacgg cggccttttc cgaaaccacg 83160 cgtacgttca cgtttggttt catcatcacg ctcacgtgta cgctcacgag tattacgacg 83220 gctattacgt tcactgcggt catcacgatc acgatcgcga cggctattac gatcgcgacg 83280 actgccacgg tcgcgtccac caccgcggcg ttcacgacgt tccagttctt tcaagtcagc 83340 gatgtattct gatgctcggc ggcgagaacc atcggcactt gaaggaatgc gtgcactcaa 83400 ctctgactta caccaacctg atagaaaggc gatgtagaag tcttccagaa tcaaatcgaa 83460 ggagtcttct ggtttgagat gatcgtctac tgcttcagcg tgttcgtaag cctccacacg 83520 aagtgcgtct aactctttac cggagttgtc atcctccatc atcatggcta agttataagc 83580 caaatctgaa ctgtcttcga ttgcttgaca ggctttaatt gcattacgtg acatgaagat 83640 tcctctttat aaataatact gtagggataa ttgaaaatta gttagcaaga cggccacgat 83700 gacgtaagtc ttcttgggtc ttgtcggtga tttctttgaa tttaggattt tgttgtaact 83760 catagttacg acctaaaatt gcatagacgt ttagtgtacc tgggccaaag ggctgtgctt 83820 ttgtcacata cccgtaacta ccaccttcca aacgagaagc atgtctgaag ttaactgggt 83880 catcgatgtt gatggtttta ccagacttct tacttttacc tcgattgttt ttagtggcat 83940 cagtttgatc aatagcgtgt gtagtcacac caatcacagg acattcacaa gtactggaaa 84000 gatgtgatac ttcaccatgg cctgaagtaa tcttggtcaa tacactcaca aatagtttat 84060 tgttaactac acgcgcaatg gaggtaggtt ttacaatgcg tgtaccagtt aactcatact 84120 ccttatctgc taaagtagtt agtttccaac gaatctcatt gatggctaca gcgagacctt 84180 tttcaccact aaataagtaa tctacggttt taaggcattt tccataaatg ttacttagtt 84240 cggaacgagg tatgttgtgc acatctatag tggaacgaat gacgtggaat aagaaatccc 84300 aaatcgtttc gacatcgtcc acaccagatt caagtagttc atgtttaaaa cgggcacagc 84360 aataacgttc aatctcaatg aagtttttct ccatctcctt gtagagttgt gcttcgttgt 84420 ctgccgctga acggccttct aagctataac ctagaattct cgtccagaca tctgggtcat 84480 taatgatatc cgctgagaga tgatcaggct gcgcttgctg cgcatagaac aatgccgaaa 84540 tcaaacttaa tgcttgtttc tgcgctggtg ttctttttgc aatatcgtgc cccatctgct 84600 cacgtggtac agtaacgatg aagttctcaa caccacgacg aatacgttta gactgaataa 84660 cagttacttc gtccagattt agttcattgc catttctgaa ttctgtatca taaacgtcga 84720 catcgatgcc agtataacgt ttgatagctc cacggaatcc gtatttagca aatagccaat 84780 acgcaaccat aggcatgttc gttttaccgc tgccattgcg actcttgaga gtttctgtag 84840 tggtgaggta acaccgttca tccataccgt gtacagatat cgtgtaagat tcgaatttaa 84900 aagtaattcg ttttgagaaa ggaaagtgta cgaaaaagcc atcgttcaca taccctaacc 84960 ctggctgatg ccaaacggcc gaaatcaaac gcgaaccacc attaacattt acaatgttat 85020 aagggttcac atatggaaca agtagcggtc gaactatatc agcttcgcca ccacggtcat 85080 ctcgcatttt aaagttgaag tcgaccatgt agtaatcgct acgtgataca tccacacccg 85140 gtgacttatt actttttgta ctcgactgcc aaccaaacat ctcttcaggt gtctttaagc 85200 tatatccgct ataatagaaa ccttcaggta gttgtttgtt atttcgacct aattcgcgct 85260 taagtaaaga gtgaattgtc aggtgtagat tgtctccgat ttggtggaat gccaaacctt 85320 cggcaatctg cggattcatc tttgcaattc ttccgcgctc atcaagtgct gctaatgcat 85380 cagcaaacat accgcttttc cctcttcgtt attatattac cttggccaaa cttgtcaaca 85440 aggttgaggt tgtcttaacg ttctcagtaa cgagtttaga ctcttcacta agcaagtttc 85500 gtgtagtctt aacttcactc tcgtaatctt tacgcatgaa gtcccttgct ttaaagcctt 85560 cctcaatttc tgaatccact ctcgctaagc caacagaaac tctgttgtta agaccatcaa 85620 gatgtttatt gaatagacca acatctatac cttttatttc tttattgcct ttttctttct 85680 ccaccttctc agataattta tttaattcgt atatgttatt tgccactatt gggtcagcgt 85740 caactaactc cactctggct gacacaccat cgttcacaat gacataaagt ccattatcca 85800 tatcgttata atgtttcaca tcaatctcag taggtttacc atttagactt acggcaacat 85860 aacttcgatt aagcccttcg caattgtaga agtactggaa gaccgagggg gtgccttcct 85920 ccactattac attactgaag gaatcctcgg gaaattcaag ttgtgagtac aaagtaccga 85980 taacaatatc taactccttg atgtaaatgc ctttctttgc atctaggata gtttctattg 86040 gtatctcacc ctgcactaca taatgctcac cgatatctgt cagtgcttct tgaatatcat 86100 cacgagttgt gaaattagaa cgtgcggaat aatcgtaccc tataccaact aatacatgct 86160 tcgtgctaag atgctttgta ttaactgttg gtaataacgc acttgtcccc agtctatcga 86220 taaaacgcaa ggtatgtgtt gtgggattcc aaatccccca cgacttacta aaggttgcat 86280 taaaccccaa acgttttggt ttatgtacct ttaattcgta actatcatgg ttcataccag 86340 tttacctcca acaagataac atatactcaa aaaaagttgg agtttgacat agtataaaag 86400 aagggcgtta aaaataaaag aacctagggc cgaagcccta ggtctttatt ccttccacga 86460 acttattggt tcaaatctga atccattcag tatcgtggtt atggtgccgg gtttgggtct 86520 gttgcgtcaa ctgtcgccgc taccttcact tcgtcagcaa tttgaattgc cagagactta 86580 cggatcttca tccagttgtc tagaccagtt acatggatta gaccagtaac aggacagtta 86640 acaacgtgta ggttacgtgg ttgaacagtc agctcttgtg caacaccgcc ttcacgttga 86700 atttgagtgt tagacactag aggtggaacc cataggtgag taccccagtt gtagatttgg 86760 tagttatcac cgtcgccatc tacagttaga acccattgca gacgacgctt gtaaccgcct 86820 tctggcattt ctgggtagta acgtaggtcg ttggttgtaa cgatcttgca ctcgatgtcg 86880 tcgccaagaa gcttagtgtt gccccatagt tgcagaaggt cagctgtaac tgtatcacaa 86940 gtgataagta cagttggttt cttatctgcg caaccagaag tagcacgtag agcagttagg 87000 taacgagaac gttgtagagc cacagaaacc tgtgcacgca gcaggttaac cagtgcagaa 87060 cgagcgttct taacgtcatt tacagactca aggctttgta caactttcgc caagtcgaag 87120 ctatcttctt ccatccaagg acggatgaag tgacgcgcga tgccagagat aggtgctggt 87180 tcgttgtcga aatcgttacg gatagtttta acaacttcac gaagagtgtc tgtgtactca 87240 agagtacgag taacagccag gttttcgtta cggatgttaa ccagcgagat caagtcttca 87300 agacgagaag agtcatctac ttggataccg tttggcggag tcttagtagt gatcgggtcg 87360 ccaaggcgga tcttgtagtt ttcttcgaac cagaacgcgt ctgcaagaag accatggtta 87420 cgtttgtttt cgttagtaaa cgtcgccgcg tattcgtagc cttcaacagt gaattcaatg 87480 ttgtcaacta gagtcttcac agaacctttg ttgtggctta ctacttgacc ttcagcatcg 87540 tacacacgct taaccataac ttgtggttgt gtcatgcgct cgatagagtc gttggtagtc 87600 acgtaagagt tcaggatgat ttcgaagttc agctggtact tcattggctc aagaggagcc 87660 gcagcagcga ttacattacc ttcccagtct ttggtcgcag catcaagtgc gaacaggttc 87720 ttacggaatg aaagttgagt ttcacgaccg tcgccctgtg gtgttttgtc gaagccagag 87780 aaagacatgt tcagaacatt aagctccatg aactgtttcg cagagtcagc ttcgcctttc 87840 ttcttaacag aaaccaggat agacttcaga gccatacctt cagcgatttc atcagattcg 87900 ttcagcaggt tgttaccgat cagcagtggg tttgaagcca acgccatcag gttacgctct 87960 gactgtttga agttcaggta agaagtacgt actttgtgac cagctacttc aacttcgcgt 88020 gccgggaata catttggatc aacgaaatgt tcgtcagcag aaccatcttc aggcatgaac 88080 gggataagag ccaggtcatc gccagttagg atagttgggt cagtcagtgc atcgattgcg 88140 ttacgtggtt cgaacttacg tgctttgtca gcaaacagag tgtgacgtgc accacggtgt 88200 gtacgcagtt ttttcgcacg gaacgttgca cctgtgtctg aagggtcgat gatcattgtg 88260 cgatacatgc tttcagcgta aggtgtttgt tcagcaacct gaacgttcag tacgatagat 88320 ttgttgatgt gcttagccag gtcttggtca gagaagtatt ctgttgccag aacgctatta 88380 gaaccgtagc cattttcgtt cgcccactca gttttgcttg agaagttctc agtagccaga 88440 gtacgcgcat aagccattgg gtcagctacc gctgctgcaa caacacgtgc cgcttctttc 88500 tgtgcaggag taagtttacc tagcttgtcg atttcaccgt tgatggtggt ggtagccttt 88560 ttaaggccag cttggtcgct gattgattca gttgtcagta cgcgtttgct gtactcgttc 88620 aatgaaccgc cttcacggcc aatagaggta accatctttt cggctttctc cattgcttga 88680 agcacggctg gagaagaatg aatatcattc aatttcatct taattttcct tattacttaa 88740 gtaatttaga actattgagt attatacgtt tacccaaagt acatggctta taaaccataa 88800 gaaatgtaat aactgaacag accagcaaaa tttgggtgat ttgcaaatag tactcgtcca 88860 ttacctttaa gtccattgac agctacaaac ttgtcacgaa tgtaacatag taactcttca 88920 atcaaactcg ctcggaactt tgcgtggtcg ctcaggtcta acgctaccga ccccggcaca 88980 ggttcattac tcatattaat aaagatttta tcttcatcag cagtgtgaga gaaccttaca 89040 tgctttttaa ggcatgaact ctgcataata taagcctccg cagagtctgt catagtatac 89100 aaaggtcttt ctgaattttc agcattttgc tcatcgttaa ggatggcagt ttgtatggtc 89160 atgcgagcag ggatagtttt ggtatcgatg agttcatgta cctccaccat ctcacctttt 89220 gacataagca atttaaacac attggtgatg ttcgaaacac ccatatgttc agctaatggt 89280 aaaggtagtt ggaaattttg gctatccaac ataagaagct ctctgaaaaa gctgtactgc 89340 atttccaaat aattattaac gtcgtgagct gttactatag actcagacaa atctttggta 89400 ctccctgatt caaaagaatc attcatccac tcagggacat actcaatttt gatattcata 89460 ggatcgaccc catatgttat acgatattaa aatagcactt aacacttcat tggcacttct 89520 atacctcgcg catagacaag aagccatcga tccagaccaa gaacttattc gttcagctct 89580 tgatacaatt cgtgccaacg accaagcagg tgacgatgac gaagcatctg caattagcta 89640 tataaaaggt ctaattgaag aacaaatccg ttctaaagac ttcgataaga aatctattat 89700 gcgtcgagtg aaggttgcgt gctcactttt tcctgacgtt tacgagaatc ttgaaaccta 89760 tctggaagaa gaaatcggtg acccagaaga agctcgtaaa acagcacaat cgcataaaca 89820 atggttgcgt cgattcgtaa accagaataa actaaagaca aacgttgggc gtctatacgg 89880 tgcattgacc cgtggggatg gtaaactagt agaagaagaa ctagcctcac taaaaaagac 89940 aatcgatagc ggacgcagtg ttgagaatag aaaaatccca tccttagtag ggagcctaag 90000 aacatcacaa ccagaaggct ttggtattgt tattcgtaaa agtcgtgaga ttctaggtgg 90060 agcatgtttc cgtacaggct tccgtggtat aaaccgtatg cttggtgcac agggtggtat 90120 tcgaatgagc gaattagctc ttatgcctgc tcttccattc aatggtaaaa ctcttttctc 90180 acaatcgtta tttcttagcg ttggtgtggt gaataaagca gaagacttcc gtgaattcat 90240 cccaggtgat aagacgccag cgttcctaga cctctctttt gagaatacac aagatatcaa 90300 tgtaccccaa gcattcgata tgctctatgg taacttagag agaaaaaaag caccgaccga 90360 acaatggtac gaagaagctt tggctactgt tatcacaaag gctggtatcg ctattccaga 90420 tggcgttaaa gaaaagaaca aaaccacaga gtggttaaag tcagaacata aagccttata 90480 tgacgaagta gagactatag tgtctaatcg tactggtaac tatatttgta aatccctgaa 90540 taaaaatggt tgggaataca ttatggacca gcacataaac actgacttcg agattcaata 90600 tctcccagat atcattgcag attacgagtc gcaaggtcta cacatcatgg gtgtgcgtgg 90660 tgactaccta ggtacgatta agaaagaagg tcttggtaac ggtgtggctg gtacagacat 90720 taaagaatct tatcgtattg cacgtaatgt aacggcgatg aaagataagt tcgctctctt 90780 accacatcag ctatccccag acgcaaagcg ttttaaagct ctcaatccta caggttatgt 90840 tcgtaaccta ccaggtaaag gattctacga gggttgtacc tctcttgaca acgaggctga 90900 tttagagttc tatttcggcg taactgaaca agaaggtaaa aactacctag aagttcaacg 90960 tggtaaacac cgtggcggta ctaagacagc aatcaaagac cactactgtg taattccttt 91020 tgatgatgta cgcatcctac catgggatat gttagacgac gctgagatgt ctaaagactc 91080 tctgtctaaa ttctcttctg gttcgggtgc actaatggag tggtaatatg catgacggtg 91140 agttactgta tgagatgagt atctcttcta ttgatggtcg taagttattg gttgactgcg 91200 aggttcttta tacctcgccc gataacctct acagactgtt cttttataag gaagatgaat 91260 ttggttttcg agccaaggct gtggagtggt gttctagttc accgggtcaa aaggatcact 91320 gggaaaatga aacttctatg gtggaggaac tattcactct gacagcaaga aaagacggcg 91380 caagacatct tgaatttaac cggagtagtg acatggctgg ttatatttat tgtcctagtc 91440 tcttagcctt aaaagagatg atggaaatcc tcatcgagaa agagaaagag cattgtcctg 91500 ataagtgata aaaaaataaa aaagaagtag cctcattgcg aggctacctt ttaattttta 91560 ttcgtcttaa caacgaacct cataagcttt gagagcttga taaacgactt tcttgatgta 91620 acggtcttga ccggactcaa aacgttgtag ggcaatcagg gcatcttcag aatcgaatgt 91680 accaaaatga ccagccaaga atgggatgat agaagcatcg acactaatga caggtttaga 91740 acctctgacg tagaaggctg tggttacttt aataccactt gcgttgcctg gaaccagcgc 91800 agacaacgca actttcgatt gcgctgttac agaatcacca cggtagaaga ttaagccatc 91860 tggtagatta ccatttgctt ctacaggttt ctttgcttgg ttcatgattt gcaataattt 91920 actaactttt ttcattttct aatatttcct tgtttatttt gattgcttac atttaacgtg 91980 agcagctaca cggtggtgtt taaggtacac cacaaacctt tcaaacttat ttctcgtaat 92040 ccaaaacagc gtatgtagca tgatgtaatt caaagctaaa gagtggagag aatatcacag 92100 gtgtctcttt accaataact agaattttat tattctttgg ttggagtaac tcttcgtaat 92160 aagtcatcca gttcttcacc atctctaccg cttcaaactt atagatcaag tccccttttt 92220 tgtttcggat gaatttgtct aaagttttga agtcgtcgtt cattttacgc atcacacaat 92280 tcacaaattc ctcagtggcg tattttggaa acttaactcc taaagaaaat ccgaggaatt 92340 ggtttgtcgg taatacaccg taagtgaatc cgttttcttt atgacatatc cagtaatcat 92400 ggccatcgag aacgactact tgtgtactgt gctctttaga cacagctttc tgatacacct 92460 ctagagcgtg tggggtacaa ctacgattgt acattagtcg acctaatcta ggtgactcag 92520 ggagaaggtt gaactccttt gcatatatgt aggttgtagc cgtcatagta caaagtattt 92580 ctcttctaac ttctgatgcc aaatcgattt ggtggaatag tacactacca gccactagcc 92640 caagacggtc aactagaaca gatgttcctc ttttaaaccg gaagtagttt tggaatttac 92700 ctgtcgtctt gacaccccag aataaaaaca gtttctttag atcaagtgct gctgaatgta 92760 gaggtaacca tttgttgtac tgaccacaaa tgtaatgaat gaatgcaggc gggtatttat 92820 ttctttcacg attgagatct cccataccca tatactcgtg aatccagtcg atggtttctt 92880 tggtaatctt tacgtagtca aggctaatct tacactctct tcctctgact gtgtcgtatg 92940 ttctcacagt ccaacgtgtc aattctccat ctctgaagaa cttagcgttg ttgtcgtaaa 93000 catccttcga taccaaagta cctaagtaat cccctgaata cacagactgg ccgtcagccg 93060 caagtgtatt tttatttttt cttaaaatcc atttaaggtt ggttagttcg tcgcgttcat 93120 tgaaatgtct taacattgtt tctttcctta tagtttggct gtggagttat tttagcccct 93180 cccgcaaagg cttgtttgga ttaaaatccc attttcttaa gtaatgcttg tgaagctttt 93240 acttgttctt cttctttccg cacagctttc tgtggggttt ttgtgaatac acttcgttta 93300 ttatcgtaag tgtaaaagtc atctgttacg tcaatacctg tttttggttc ttgaactaca 93360 ggtaaacagt agctgctact gaaccatccc gacccattga tcattttttc aatcggtgtt 93420 tctttgatct gatttaccca ccaataacga tatgtgtcta cacgcccatt agaagtgggg 93480 caagtgcacc ctgttggcgg cttttcttta gtgccgactt taaacttatg ggtaggtttg 93540 ttgttaggtg aaacaccctt atctaaccaa cacgcacaat tgtatttact gctggcactt 93600 gtaaatacga aatagagttt accatcgggc tttttaacga ttatagcgta gcggtttttt 93660 atagcctcgc gtatttgccg ttcgcgtttg ataaaccctt tgattgcttc tttttcaatt 93720 ctcatcttta aatattccct gctaacttaa acaacccacc gtcgtatttc ttcagtaact 93780 tatctatttc tgttttagcc aaaagacgta gttctttttt ctcgttagtg ttgaggtatt 93840 tcatcatcca cttgacggag tcttcattac accgccccat agttttaagt agttctttgt 93900 ccatcaaacc aaatacatgt atgtttgaca gcggtattct gggcttagcc cttttcaata 93960 cttctcccac taactccaat tcccaaactt tcacattgcc tactctgaaa gctggtgtta 94020 ggcttctatt cttagtggcc tctgtaatcc gataaccaaa tactctttgg atgtcgttat 94080 tggtcacata accacccaat cgcatcaatt tccttaatct ccaagagacc ttggttatag 94140 agacgcgttt atagacgtca tcgaaattgc tctttctctc tggtggatga tcgatgagca 94200 attcgaatac atcacttatg taatagaata tacgattgta aaccacatgg tagggtaacg 94260 ttatcaagtg ttcgtctgac gtgtatagat tgtataattt ctcgtaaatt tcgccagtca 94320 ccacactatc taaatcgcaa gtgttcgtta ataggtaatc ttcgaataga tgatgtagat 94380 tatcccaccg tactatcttt ggttccgtta gaccattgat cattttaagt atcctctgag 94440 ttatcaaatt gaacatgttc actaaaataa tatataaccg aaaaatatta gaggaggcta 94500 ccgaggatta actcggtagc agattattaa taactgtgta gcacaacatc acggctcgtc 94560 acagcttcca gatcttcgtg cgggttaaac ttctgttgac gatgtggcat cggaatgata 94620 gcgttaaagg cgtaatatgg tccgctgata acgaatgggt gaatacgccc atatccttca 94680 tcgccttcaa ctgcacatgt gtcgaagtat agacgctcta ccgctgttct tggtaagcga 94740 atctcgttag acgcttcacc ttgaagatac agagggttaa ccacggtgat ttcataatcc 94800 ggatcgaaat gctctggggt gaaacgctct acaaacgaca tggtgtcgaa tcgacgagtg 94860 atgtaactga atacgtagta acgataccac tcaggttgat ttgccagagc atggtacgtt 94920 ggaccaccac aacaaaccat cttgattagt ttagcgatga actggtcagt atcgtcccat 94980 tcagcttcat catggtctag aacaaacaca atgttttcta gatttgggtt tttcaaaacc 95040 actacgagtt gtagtgagtc agggtcagct tggaagaact taatctcatt agccgatacg 95100 cctgtgattt tctcaatgcc agcttccatc gtctcactgc gacgaagatc gaacaaggtt 95160 gcttcgtatt cagcaatggc tgttagagtt tccattggag caacgtatgc cttcattcta 95220 ctttcctttt ttaactattt acagggtctg cataaaaaga cagaaccctg taatttttta 95280 cccatgtgga aatactagca aagttaagct aatggtattt cggtgttgtt tctccataat 95340 accaccacct tcaacttcac taaactcgga ggaggccaat agcgtccctt ttacacgttt 95400 aatggtattt gattgtgggt atatcaattc aatgcccata ccgggcttga gagcgtcgta 95460 gagaccgttt tcccattgaa ctgtaacaac cgcacccctt cttctaaaaa gctctgagga 95520 agcttttaga ggattatccg tgtagcgttc tgctaacata ggggcattcg tcatattctc 95580 tctggggtta gtgttaacct cagtcaaata tttcctaggg tcgatgttgt tactatcccc 95640 aataccacga ttctctaatg aacgaatatc ggcaaatcga atacctgtcc cctcgtttac 95700 agcaacgtca tcgatagagt taatgacttt actgtcaccc gtagcagcga tgtaataaac 95760 gtcaccttcg cgatagaagt ttctatcggg tgacatcatt tcatcagttg ggacgttata 95820 gatgactaaa cgttcaccac cttcgtcgaa ctttgttggg ttgtagggtt caaacagttc 95880 ccatgtttgt ttatatagga aaatacctaa ccctttgggg taaataccat atcggttttg 95940 aaggaagtcg aatacttcta ggaaccgctt cccttcctcg attatgatac actcgtagtt 96000 tttcggggtc ttgtcaacat agttgataga gtagttgaaa tcactggttg ataacgtgtc 96060 gtctaattga ttctttttta gtaggtaacg tgcgacatcc agagcgttgg tttcgtgaaa 96120 tggaccacca acggatcttg tacgcaattg ccatgctaat ttatcaagta gctcaaccac 96180 caccacagcg atagtttcat tatccatacg ttcggcatta gccatctcac gagaaatggc 96240 acccatgtca acgtcctcgg tgtttgttgc ttttgccaca taagtctttg tggagatgac 96300 tttgccatta actcgttttg ttaaggacaa ggtcatgtct tcataaccga gcctcatggc 96360 atatacagca accgaggcag ggactaagag catcatcttt gttatctcga acatattcga 96420 gtcgtagttg ccctctttgg aaaaagcttt taccgtgtat actttttgat aagcaccacg 96480 tattgataaa acgccctcgt actggtattg gggcgacaca atacattttt ccaaatgtcc 96540 ctcgaggatg ttattaaaaa cgccttttct caaactcccc tccttctaat cgactttgcc 96600 tacctcttga ttttcgtctt ctgtattcag attcaataaa ctcaatcatg ttttcattat 96660 acacttcaag tttatcctta tacgtttcgc cgcgcagact agcgaagaat gattttctaa 96720 cgcgtagttt ggtgtggtaa ttatccagcc tagctaaacg aataagctca gaactcagtt 96780 tagaaaattg tcgcagccct tcaatcggta tatctctttc aatcaacctt tctttcttaa 96840 ggtagttggc ccagtcgatg atgtggtctg tcaccacttg gaaagttata attgccgttt 96900 ccttatccgc aggtcgaata cggtgacctt cgtctaacac ctcagcgact tgtgaggtga 96960 agacgtgtac cggaatcatg tcactggcaa tctttctatc tgtgtctagg ttacctgttg 97020 aacggcgacc tatcactgta gcgtattgtt ggttatcgac taggtagttt ggaacgtacc 97080 acaaacgtgg tactttaaat aaccatgtag cgttactaca tttcagtttg ttttcatcgg 97140 acataatgca acaacaacaa aacaataggt gagaagtaaa actgttctag tggctctagt 97200 tcaaacagtt tatcataaag tcctattaac ttatcgacat caatagtttc tttacgaaca 97260 tactgtaaaa ccattcgctc tagttcagtc tctggcattt cattgtaaaa accttcagaa 97320 aacacataag gtttcaacgt gacctttttg aatggtggta attgattttc ggctaattca 97380 ccccagtcat attcacggtc tgggttctca cgtcgtaaga ttgactggga tggcgtatac 97440 ctcaccgttg accccatagt cttcatatca ccagaccaca tagtcatgaa gtattgtgag 97500 tagccgatgt tattgatgta ccgcttacca cggaatggtg caatatcaac caaacccatt 97560 tctttcgcca acattttgaa agtgtggcga tgtggcttca ttaacaaaga ccaaagagtt 97620 ggtacttcat caagtttaaa cggtggatag ttgtaaacac ttttccgttc aatgccaacg 97680 aatggtaaga aggtttctat aaaaccatcg ttcattggtc tagattgctc tggtaaacta 97740 tacccatcag tcggaagata catccaggtg tggaaataca cttcttgtaa gtaacgaata 97800 tcgtctttga ttttaattaa ccgattgtaa ctatcctcgg ttatcaaaga ttcgccagtt 97860 ctttccagat actctggtga gtaaaccatt gattctgata tcttagaatt gatgatgttc 97920 atcaacgcat catcaatcac ttgtttaagc tgatactcga tacgatagga agcttcttta 97980 cgatgagaca tcctctctga gttagtcacc aaaaacagac ctaattgacc atcaccaata 98040 tcagcaacaa aaacatcgtt attgttgggg attaaaccat gatcaatata accttcacct 98100 tgaacagtaa aggtcttatc gtcggtattc tgtgtgcttg tcaatggact aacgacacgg 98160 ataatcaacc ttttgatctc acggtattgc tgcgatgggt ctttgatgta tgtgtcaaag 98220 tcggttgaga tattgtcact gcctacacgc attgaaagat aagatgggat agtccactta 98280 gcaccttcag catgttgtat tagacgagac ggggatagac gttctgtatc tatctcaatt 98340 cgacgagctg gttcactact cgtctccacc acccctgtgt tatcttgggg tactggtttg 98400 ttagttgcgg gtctaccaat aagcatttct taaccctctg ctttcttaac taagatagag 98460 ttgttgtgaa tggtaatcat cccaatctta gtaggttctt tactaacggc cttggtgaca 98520 tcatcaagaa cagaaacagg cactctgtct ttggtgatga tgttttccca atcgatgaca 98580 ttgtcattgt tgccgcacga tggtctctgt cctgggtacg aaggtaaagt agaaccatta 98640 ccagaaccgt tcggttgtgt taacgatggc gcaatagcat caatgtactg ccataatacc 98700 ttaggaaact cccttaggct atcgattgtc ttattggcat cgtagcttaa ctctgtcact 98760 aactccagtg tgaactgatt acgtttccac acacggtatg gtgcatcaga ccaaactaac 98820 agattctcat ccaaccagac attgagtggt tctacacgta gaccggatac atggaatcct 98880 accttgaaaa tagaattcaa catgtgcttg tctttaacag ccacgtactt taaatactcg 98940 atgaattctg gagtgaagcc aaatggtaac tcgttaagat cgatgataca gtacggttct 99000 ggattattct catcgtaact ttctggtgca cagtcagaag agaagaagat gactgtatct 99060 ttaccacttc cgccctcgta gtccactgtg aaatgccacg gtagtttcag aacatagtca 99120 tcgatatatt gttctgattc tatcaaaggg tttttgtaac ctgttctttg aacaatccaa 99180 ggtgggtcca actctggcca ataatcttct ggcatgggtg aacctgccac cactacaggg 99240 tattctatcc gtaattccga tggtctctct aaacggaagg atacggagaa tgaagtggta 99300 tagttggttt ctcgtttatc aaaggtaggt tcttcatggt cataaatcaa atggatgcct 99360 gagatttgtt ttctcgcgat gaactgagca cccttgccat tttgttttgt gccgactgtt 99420 acccacttgg ccagattctt caagaagaac tcatcaactg gacccgcacc caattcgtct 99480 ttttcacaag cagtggtgtg taagtcgatg atgacttgta atgcttcgtg gggaataggg 99540 taactgaact ccccaccagt catgatggca ccttcaccag aattgattct ggttcttagt 99600 ctctgaacaa gacgtttagc ttcatctttt gaagtggtgc gaaaagacaa agttagtttt 99660 gtattgaatg tttcacagat aggtgttatc ttcaatccat atcgggaatc aaagaagata 99720 tcctcttcaa gattgatatc cacactacga acactagcag agtgggcatc tggttcttca 99780 tctacctgta cagtgattgt tttaatatca ccaaagtcaa ccgatgtttt aaagccttca 99840 gttgacagtg gttgaaagtt attctctagg tcgccttcgt actttattga tgttttaggg 99900 tcgagaccga caccactaat caaattacga acaacgctat catagagagt cttacgaaga 99960 acgttatcta cgcttgataa cgatgtgatg atacgcatgt ctcaactccc aatttaaagt 100020 cagtcataca aacagttatt gatggaaaaa ataaaagtta aaaagcccaa ccgtttggtt 100080 gggcttttat atcgcttatt agtaaagtat tactctttac cgtaagcgcc gatagcagta 100140 cggatgtagc cagatagacc ttttgcaagg ttaacgcgac acttgttctg taccgattcc 100200 atctgaccga tggaagtgat gatcatggta acgccacgtt tgatgtcacg tgcagcagct 100260 ttatcttcag aagtttcagc gcctttacca gcatcgtttt tgatcttctc aagatcttta 100320 agtgccttag cacgagaaga ttcaacctta cggaacttgt tgatgtaagt ttccaggtct 100380 ttaccgaagt cacccatcat gtcgttcagt tcagaaagaa cgccgatttc aggagtgtcg 100440 acttcagatt tcagatcaga tttgtcaacg gctttgatat cgaatgcgac agatactgtg 100500 ccttcttttt cagtcaaagt tacgcgcgct tcttcaccgc ccaagatacc gtctttaacg 100560 ataagtttct taacgccttc ttcaacagac tcagatgcag acttagtcat gctctgtgct 100620 actgccttaa ccttagacgc ttcgccttca gccgattcaa tcatcttgat tgcatcttcg 100680 gttgcttttt caatagcacc gacgtcagta cactcagcac cgattttttc tagcgctgct 100740 acgttgttac cagcgaactc tttaccgata gatagttgct tgatgaaagc acctttgata 100800 gtgtctttct tcttgctacc cagggtatcg atgatcttag cgttggtttc agattgactg 100860 cgtagtgact taccagcgtt aacgtatttc ttccaggttt cgcgagcttt gtcccacaga 100920 gctttaatcc actcaatgaa cgcttcccac atacccttca gagtatcaga aacaccttcg 100980 cgtgctagaa cgcggttgtc tttacggtca cggccgaagt tttcacgaga cagcttacga 101040 gaaggctgta caccccaacg acgagcgatc gattcagttg cgatttggat ggtttcggct 101100 tcatcttctg aaacttctgc atcttcatct tcaagcttgt cttcaacctg ctcaagagtt 101160 tcagtatctt ctgcaagaac ttcaccctct tcaacgattt gaatttcgcc atcaacttgt 101220 ttttcaagcg ccgcaagatc tgagtcagtc tcagcgtatg gtgcgatgat tgtttggccg 101280 tcattctcta gacggatatc agcatccatg ttttcgcgag ctagttgacg tttacggaag 101340 ttgctcatta cactttcctt ctaaatgttt tacagatgtt tgaaaaggca gttgaacaat 101400 caactgccta atcgtacggt ttcaaaagac gtgattaagc gtctttcttg tatgctgcga 101460 taccagcgtt aacaagacca gacagaccag cgccgacagt tttgtaaacg taagtaacag 101520 ctttagaagt gtgctgtgca gaagtagcag cttcacgagc aactttctgt gcaacacgcg 101580 cttggtcttt cgcttcacct ttttcagctt tgccaactgc tttctcagct ttcttagctt 101640 cgtccatcag ttttttcaga ccgttacgag ttttagtaaa gccttgctct actttctcga 101700 atgctttacc gatgtcttcc atcgcgtcgt tgcactcttc aagtacagct acggttggag 101760 tatcgatttc tttttcttca gttgagtctt cgcctgggtg tagacgaact gcaacgattt 101820 gcgctttcac cgcagaatct tcacgaggtt tgtactcgta agaagcagac tgtaggtagc 101880 cgttaccagg cagagcgtaa acagtttgtg actcaccaga gtctttaccg ccaagagatt 101940 gaagtttctt agaaactttc tcaccgaaca gctcacgagt tttctcgccg tcagttacgc 102000 ggttgaactt agcagaatcg ctgtcttggg tagtagcgat cttaaccagt tcgccagcag 102060 cgtcaacgaa tttttcagag gccgcaagtg cagacttagc tttaccgtcg atagacagtg 102120 caagttgaat tgctttctta gcgtcgtatt taccttcgat agaaagttta gtaacgaagc 102180 tacctttgat cttgtctttt gacttggtgc cgagtttgtc aaggatcttc gcgtttttct 102240 tcgcacgaga ttgcattgac ttaccagcgt taacgtattt cttgaacgtg tcgatcattt 102300 tgtcgaccat ttcgctcaac cattcgatga aggttttcca catgtctgcc aggcggtctt 102360 tgatagactc gcgaaccagt tttgtgtcgc cacggcggcc agagaaactt tcgaatgcca 102420 gtttacgagt gcttgcttta ccaaggctcc aacggcgtgc gattgattca gttgcaattt 102480 gcagtgtttc ggcgtgctca ggagtgatct cttcgccatc ttcttcgatg tcttcgacct 102540 ggtcttccat cttctctaga gtctcggtat cttgctctag aacttcgcct tcgttaagaa 102600 gtgcgtagac ttcttgatcg tctttgtcga cttcgccaac ctgagcttct actgactctt 102660 caactggctc tacaacattc agaacgtcag cttcgcccat gttttcgcgt gccatacggc 102720 ggtttttcat aaatgacata atgtcttttt ccttatcgtt aacgatttac tactttcaat 102780 tgaaaggttc ctgcctagcc gttatgatca ttcgaccagg caagacattg ctaataaact 102840 gttcaccatg tcattaacag catttggatt gttcatgatg cggctaatga aagggtggtg 102900 ttgtgcatat aataaatcct gaactggatt tacacgcttg tcatgcttac cgtaataacg 102960 ctctgtaccc tctgggacga aggtaattcg acctgtggtt gacagagaat ctactttaag 103020 aacttgacgc tgagacgatt ctagatgacc taccgagttt ttaattaact catagcggat 103080 tcttgattcg accaattttt tcttatcctg aagaacgctc ccaacgaatt cgttaaagaa 103140 ctcataatat aaggttgcga taggaccgta cttatcatgg agcatgatag cggactcttc 103200 agtactcaac tccacccata ccgggtaaag ggcagcaatg gaacggtaga gcttggccag 103260 agtacgtggg tggtctgctt tagcactccc acgtttctgt aagctacggt actcgcccaa 103320 cactgctaag tggtgagata gtaacatagc tcttatcctc gctcacgtaa accgtactgc 103380 tcttccgtct tgataagttt gcgctgtaac tgagatagac gttcttcttg caaagaaatt 103440 tctttctcaa tgttggcatc gccttcacca gactcctgtt tgcgcttcag tgccacgaca 103500 cgatactgca caagtttgga ggttgcttcg agacgctcaa gacgatccat ctgccagttt 103560 gcaatcacca tctgcggata gaagatgata gacagaggga atggaggcac agacaagttt 103620 agagggtcag cgttaccgtg acctactact tcaactagct tgttatactt ctcgctatcg 103680 gcaagaagcg ccgggatttt accgtaagcc gctttgatgc tactcaaatc acggtgcagg 103740 atatccatcc caataacaaa gctaaaacga tgaatgctta ggtagtcttc ctgtgtcggt 103800 gttaacttac cgaccttttg attcgaaccc gggatgctat tcaattcgta gaaagatgac 103860 acgttcaaga actctgtcat gtaacgaaca gtgaactcga ctaagtcaac catttgcaca 103920 agattagatt gtctcagctc catcccttca acgtggatgc tacgggctga aaactgattg 103980 cctaaccaag gcaagatgtt taggaggtta cgaagtagtg atacttggta atccagaatt 104040 gttgggttgt tgattcgttt aaggaagatt ttttcattct taaattcgtc aaggaagtac 104100 ttgttgtact cacccataaa ctcagagttg aagttgccat ccaagacttc gctcagactt 104160 acgaaagctg gaagaagctc tcggctaatt tcactctcta agttggatag gttgttctta 104220 acatcgctgg tgttaataga acctttcagt ttattcttcc attcgtctaa attgaacatc 104280 tatttcccct taacgaccca ttggtgcact gccagcgtta tatgcacgga tgatctcatc 104340 cacatccata ttattaccgc ctttagagcg acgcaggtct ttaaatggaa cttctgttgc 104400 atcgtcaaga ccacggtgat aaatagtcac ctgctcccaa cgttgatcaa caaccaaaat 104460 aagcatggtc aaagtgtctt taaatacacg agagcgaatc tcgaaatcag acaaaggccc 104520 acccaattct acttctaggt catcgactgt ctcttgtgag gcaacgatga tagaagaggc 104580 attgttcact gaccagttca tgcttagtag accagccagc cagttattag aacggcggct 104640 catcactttc tggtaatacc cggttttatc acggtgtcga ttcttacgca tctcatcaat 104700 gatgtcacga gagaacacga tatcacgtag ccacttcagg tcaccagctt tcgctttaat 104760 gatacgttct tcaaacatca tcgacatgcc accgacaccg agaacggatt tcagtgactc 104820 tgggtcgatt aaactaacgg ccaaagctac tgtcaaattt actggtactt tgttaccgtc 104880 acgttcaatg atgaattcga attgtttacc cgtactaagg tcgtcattgg ttgacaacac 104940 tttaccgtaa tcgcctttac cgaaagcagc accagtagcg ccaccgttcg agaacgattc 105000 agccatcagg tatgaagcaa agttcccagg ggcacctaat gtcccaccaa tcgactcggc 105060 accaaggtaa cgcataagac caaggccacc tgccactgca cctttaacag ggtcacgctt 105120 aacggcaact ttatccagtg tgcgaccaat gttaacaccg gggataccga tgatttgact 105180 tagcgagctc aaatagtatg aggacacaag ggtattagcc acgcctagga tgtcgcgcat 105240 ctctggcaga tcggcaattc ttgtttcgac taaggtaatg aaatcgttgc gagtgtttga 105300 attaaattca ggcaaggagt cggctttgtc ctgccataaa tcaccgaatt tagtgactag 105360 gtccactatt gtattagctt cgctcataat cttaaattaa cctcttttta aaaggacact 105420 tatacaaatg gctatgttag aaaaaagaac tgttgatggt gttaccaaat acaaagtaga 105480 tggtgtcccg gtctccaaag aaatctacga aaaaactcaa gcagaccaag atgctgcctt 105540 cgccaagttc aaagaagaac acggtcttag agaaactgat atggataggg ctactgcaca 105600 ggcacgttca gcgactgagc catcaccagc accgaaccaa gccccagtag tcgaattaaa 105660 gatggacaca gccccagtgg tgattaatca agttaatccc gcacagagac ctggtacatc 105720 gcaagcaagt atgccaatcc tagatactgg aacggtatct aacaccacca cggactcatc 105780 aggtaacgaa caagttctct cttccgcagc ttctgattct gccaatgcga aaggtactgc 105840 acctcttagg gtagacaaca cacgtgaccc taatcagatt tggaagaacc gaatcggact 105900 gtcactaggc aaaggtttgc caaatgagtt actaaccaac gcattaagcg gttttaatca 105960 taggatagtg acgcagagcc taccacaaca tcgtgagtta caaggttatg tctttattac 106020 acgtcccgat attaacttgt cagaagagaa tatagccaac tcacgtttct ttagttggct 106080 ggcttcgaag cctgtggaca gtgttgaatt tagtatctta gctgctttag accccgagtg 106140 cccattgact aatccacata aaagaagggg tatgccaact gacgccagaa tcccttttga 106200 caacttacag gctttcactc cgatactgac aacacaactt cgttctttat ctggtttccc 106260 tgaccagacg ttggatgtct ggatgagtcc tgaaggtgct ttccgtgaac agtatgggat 106320 ggtggattct gtttacgaag ttaacaacgc tttcacttta aatgccacat ttaacaactg 106380 cattggtgat ccagtgatgt tgtatgttcg tggaattatg gaatactctt ccggtgtgcg 106440 acgtggttta tttaaaccga agacatacaa tcaggtctca cgaagaattg attaccagtc 106500 tagaatttat gtctttaaat tcgacccaac tggtagacgt gtaattaact ggggtgcggc 106560 tatggtagcc tggccaatga atgataacga aggttcattg ttaaactatc aagcagacag 106620 aactatcgta gacgatactc gtgaaatcaa tatacagttt caatgcatcg gtgctcgtta 106680 cagagacccg ttgttattcg agactttcaa cgagacagtt gcgatgttca accctgacct 106740 tattcctgac tatggtgccc cgctaccaag taacggctct gaagattctt tacagtataa 106800 ttcatattcc ccaattgggg gtgatgggtt agtagagatt ggtgaagagt tactaccaat 106860 ttttaactgg tacggttatc ctattgttga cccagacaca aatgcttttc gatggtttgt 106920 ttccatcgaa cagtacaatc gaattttaag agaaggaggc gtccgtgtct aaaacgattc 106980 agaccttggg tgctgatatg gtatccgttg ggcagaaccc acaagctatg gctagaatca 107040 tgctcaactc gttgtccgac agagggttgg aactagcttc tccagtagac ccaattgtgt 107100 attcagccga atgttctcta atgagtggac acgctacact tttggccaca gataatgtat 107160 tatcaaaaat ctatagtagc atggcgacat cgtgggccga tttgtacaga cacatgtctg 107220 acaaagatgc cgttgactta ttctatcagc caaccagaaa tcaattcatc tggtcttatg 107280 atttagaaga gttgcgcgat gcagctattg aaatcgatga tacaggtaca aagaaaatcg 107340 tcattccggt agacacaatc taccaagcaa aggacaggcg ttacgctcaa ccgtacccta 107400 ttgagattcg tttcttaagc aatgaatgga ttcaagtccg ttgggataca tcggtcgaga 107460 acccagtgac taatatccct gctaatgaaa ttgaatggca gaaacgccct tactccaaag 107520 ataacattca gcgaactttg ctgactatta ctgtcccagt agaacaatac gaaattaggc 107580 atcaaaagtc acaggtctta cctagactag gatgggaaga gacctatact atcgacgata 107640 attatttcac cactcgtatg tggtacagaa aagataatcg ttgggctgag atgaagattc 107700 accacagcat agatgtcatc gatccacttg agccaacagc tgttatcacg gtcgctgaca 107760 aaagaatcac cctctccatc cctgaagtct acatcaacac gggtttggtt tctggtgatg 107820 ttaaaatgtc tatttactcg acacgtggtg ctgaggtaat caatctttca aactacccgg 107880 tctctgactt tagttgggta tataaagatc atcttggtgt aactgactct gtttactaca 107940 atgctcttaa aaaggtagag accatctctc taatctccat cggtacaagt acaggtggtc 108000 gtgatggttt aacttttgat gaagcaagaa aacgcgttat tgccaacaca ctaggcgata 108060 gacaaaaccc cattaccgac gctcaactaa tcgataactt ggctgaccag ggttacgaca 108120 tctataaagc tgtcgatgta ctcacgagtc gtatttatct tgcggctttg gctatgccta 108180 agccgggtgc tgcaaatatc tccggtgcaa tcggtacggt aaatgaccct gttactttaa 108240 ccatctctga tttggatgac caccctgcca ttttgaagaa tggtaatcgt tggacattga 108300 ctgatgaatg tttgtttaag caatggtctg gtaatgttgg tttattcaaa gatatcactt 108360 tggcccaatt gaagtacctc aaaccagtcg atcgaatcga ttacttaagg gacttacagt 108420 tgcttaattt acccttccat gttgttcttg atattaataa cgacattgtt gatgggagag 108480 cttacgcgat taagaaacct tcgttagttt ctcgcgtaca tcgaatgagt aacgataact 108540 tacaattgga ggttagtaca caactaatcg atgttgttaa aaagggtaca aactacgaaa 108600 tcacagccgt tactcgctcc gatgcaaact acaaatcaat acctgttagt caacgctccg 108660 cttatctaag cttcgacaac gacggtgatg ttgtatatct tggtggtgag cgtattggct 108720 catatggtga tggtgaggac cgttggctat ttcgtgttga gaccaatcta gatattgaca 108780 ggaacgacaa actcattgtt aataacttta acgagagtaa tgggcaaggt tacccaatgg 108840 cttgtccatt gactgttgac tttaacttgg tttatgcact cgatggtaac tacaacgaca 108900 ccgaccttac cgatatcgac aattacatcc cagggtgggg tagtggcata ggtgcctcat 108960 tggacactgt cacaatcgag tttggtaaac cacttagtaa cttgtgggtg aatgcaagag 109020 ctatgccggg tgcgattaaa cacaaggtct acgaggagga tgtccctaag gtctatctga 109080 aagatgaaat tatgactgac ccggaaacag gtggttataa atataacatc gtcgatggtg 109140 atattcagtt tgtttacgca catcgcaaag gtgaccctat ctataaagac ggtattgtac 109200 aacttcgatt taagaagggc gagactgttt ttgaaaatgg ccaagctgtt gttgaggtgg 109260 atcgcaaaat ggacctagag tctaatttgt ggttggtgga tgttcgctat cttgtaacag 109320 atgacacaac cgtggctgag tacaacagct actggtatga ttacgttatc gagaatgcga 109380 tgaatgttct accgtcattg gctaaatccg cgttagaaaa cacagacttc ttcttaactg 109440 ctaaaaatac agtagcgaga atcaaagtca aacttggtaa tgagacagtt aactacatcc 109500 ctgctgaaca aaaattcggt attgattact acgttactga caacgttaga caaaaccaag 109560 agttactggc gcagattaag gcaaccacca atactgttat tgagaactat ctaactagtg 109620 ccttaactat ttctacgaca gacatcacta agcaattacg cgaaacccta ggcgataaca 109680 tcaagggtgt ggagatgcgc ggttttgaaa atgcacaaga tacacgtatt ttcacaatcc 109740 ttgatcagaa tgcacgtgcc accatcgcta aacgtttgat tatgtcggcc gaaggtaagg 109800 ttggactaga gaacgatatc tcaatcagtt ataaccgtta ccgataaaaa aaagaaagag 109860 tacaggcttc ggcctgtact ctactttatt ttttacagat ttttgtggat tttgtaataa 109920 tcattaacga ccgcattcaa caacttccaa gatgtaaatg agtccttgat tgttctcaga 109980 acaccttcga tgtgtttacc cactggtatg ttgaacgcca cgttcttgaa tttaccatcc 110040 ttctgcaatg caccaacttc aatacccttg attggaatat cgtaaacaaa gaaatccttc 110100 cctttgtttt tttccctatc acgtgataat tccttaatga cgctgtaata ggtatcgtat 110160 cgcttctcta gttcacgcag tgcgccgtcg atgtttttgt aatcatcggc gtataactgg 110220 ctgattcctt caagtcgcaa ttggatattg tttcttggat tgtactcgcc gtgttgctca 110280 tagaacgctt tagcgtaagc ggctggacca tcctcaccct caagactatc gaagtagctt 110340 cttaccgcga agtacgcttc acgaccaaca gattcgattt tgacaggttc tctatcaaaa 110400 cctataacgc catctaactc tttacgagta agcgattgcg gtttggtgtt ttttgttggt 110460 ttggttaatg ggttggttgc tttgacaatt tggaagtcac tgttctcacc taactgggtg 110520 acaacatgat cgatgatact ttgggcatct tgtctattaa gatcaacctt attccataga 110580 tagaagtttg caagagtagc gtagcttttg ccgaactcgc gaacggtcaa ctccgtccca 110640 aggaagtcgc tcaatttctg acctagattc tcaaggtttg tgatgttacc atgtaaatca 110700 taaatgcatt gttcagaaac aaaacgaacc cggtcgtttt tgaactcgtc agaattcaac 110760 catgctcttc tttgcgggct accttcctcg atgtcgatca aaccagctaa ggtactcacc 110820 atcggtgaca acggtcctct gtaaccacct tgcacaaagt tgatgaagtc acgtgcaact 110880 ctttttcgca tagagtctgt ccatgcgaaa tgtccaagag gtacattgtt atcaatgaaa 110940 gtaaagatga tagcaaaacc accacgaagc agttcttctt tcttcttaac atccatatct 111000 aacgtgttga cataatcaac catctctgct gcaacttctg cggcacaacc agatgtgttg 111060 ctacccggtg ttcttaagtt acctggagac gcgtagttgt aaagacgaat catctcttct 111120 ttgatgatgt cagagaatac accgtacttt tgttcaaccc actctttcgc agcatcgttt 111180 gctagtgctg acaactcttc attgattttc ttttggcgtt cagtaggtgc tctgttacga 111240 ccaccgccct ttccacccat acccttagaa ccttcgatac taagagaaat caacttcaag 111300 atggcaccaa tgataagagc cataacagcg taacgaatac gttcacccca gttttctgtg 111360 gctaatagta tctcgtcttt atagccttta ctgctagtcc cctcgaccat gaatgacttt 111420 ggttcaattg cagtgtcgtc gatgctgagt agtgtttcca tggcttgttt atcggacatc 111480 ttgtcgatat tagccactag gtcatcggct cttcgcatta gaccgtcgta ctcagttagt 111540 tgagtttcta ccaaagtcac cgttctatcc cacgcctcat caagggaatc gccttccccc 111600 aaagattcac gagaaagact gcgctcaagc aatttctcaa cctcatcgat gtaactctta 111660 cgatgctttc ttttcgattg ggctaaacct agtgtgatag cactaagttc cattacgcca 111720 cctcgttgta ctctttgatg tagttgttaa ctactggaat accacgttcc agccaaccat 111780 aaataaagtc agctgcccca tcacattcat gttcaataaa tgctttaacc gacggttgct 111840 caaacgacac gataggacaa acaaagttct cccaacgtga ggcgtagatt ttatctgcat 111900 ctcggaggac tttctgagac ggtaagtaca tcgcctcacc tgcttcacta acgagtttga 111960 taacagcgtt gcggttatca gccattacag cttcttcgct gttatgacaa cctacgacca 112020 ttgggttaat gtcacgatag cctacaaatg tagcgatggc tagtgcaact aactcagaac 112080 gtttggttaa cacagtcgag ttatctgagc caccgttctt aaggtagcta cccgctgctt 112140 catttagctc tgttaccaga gttttcaatt gatagtgatg tgacatgatt aaccttccaa 112200 tacgctttta acaacgaata gttcatttgc agagagttct tccaattctt ccatgtaatc 112260 gcggagttgg ctatcttctt tgcttttgcc gagatattta ccagacataa tccgacccat 112320 gattgtagtc acgtctggtt tctctttgat attttctaac agcccacgaa caacactaag 112380 gtcttcttgg ataccctctt gttcttcttt ggatatgttt ttgactttta ggcgatcgat 112440 gataccgcgt tcaatggcct ttaaacgacg ctctggggta tcgtggtctt ggaacgtctc 112500 atcgttcaag ttaccataca aacttgctaa tacagccatc acagggacaa atacgctagg 112560 tgccaaagaa ctacccagaa taattccaat gactttcaca gattgtgtga tgtagtggaa 112620 tgtattaggg gtgtaatcac tactgcgtag aatagcaggc agttctttat ctttcttaac 112680 taacgctgtg gctaacgctg caccaccacc cattctggtc actatcatat ccgataaacg 112740 ttcccatgaa tgattggcgt aagtgactga acctgtttca gcgcgtcttg ctttggcagt 112800 ctcagtcact agaaccttgt agagagtgtt cttggagcta gcatcggcaa taacgtcgct 112860 actttggaat tcaacaccaa tgacttcacc gacttcttca attaactgga cacgttttac 112920 tttgtcctcg acaccaagaa tacggtcaac actggcacta atcagatagt tgtaagagac 112980 aacgtctgca atagctgcaa agtacgacag tatgtgacca acctcatggg ttatggcttc 113040 tgccaactca cgtgcagtcc aaatctttga gccgaacata gagatagaga tgcacaagcg 113100 acaattgatt tcgctgaaaa tgccatccac ccgtgcattg actaagtcta cgctaccaag 113160 taaaggtttt cctttcttga tagacttaag agcatcgtgg tcgatgtttg caaggaactt 113220 gcgtttgtaa tttgcaatga ctggattgtt ctttgtaagt gtgggtgcaa agatagcaat 113280 ttggtagtaa tcgtcatcac caccgattga agaccatggc accatactca ctgacaaatt 113340 gtggttgtca ttaagaacag caggaatttt tgaatgtctg tatcccttct cagagaaatc 113400 acccgcatcc ataaattctt gaactgcttc agtcaaagca tctagtcttc catcagccgc 113460 catggctttg aaagcttcgg cacttaaccg tcttttgttc atgaacatgt gtttaccttt 113520 tttaactgcg aaagtatata ctatagcata agaattgcaa cgaattactt cgagaggaaa 113580 tatgagtatt aaaccacctg tagagatagc gggatacgaa tgtaagaaca ttgcttacca 113640 gaaggcaata gacggtagta ttgacgatgc tatgttcgtt aaagagattg tccactacac 113700 ggacggtagt acagaacctc gtactcgtct cgttgagaac ttcgaacgac cattctacat 113760 cactttaccg catctaagaa atcaccaaga aaagaaagaa tttgaaccag aagagaatct 113820 tcaaaagttc atgtcgacgg attctaactt atctaatgct atacagctag cattgggtag 113880 ctcgttcccc aatccacaca agcaactaag acagatttgt gatagcccat atatctatta 113940 tgctgacttc actgcgccga tgtatcttaa atcacgctac atgatgaaat ggcctgaact 114000 aaagaccatg aataaggtgg cggttctcga catcgaaaca aacgaatatg aaaaaacaaa 114060 agaagttttg atgtgttcag ttgtggtcga taataaatgt tatttggcga tcactaagaa 114120 gtactacgat gagatgtgtc ttaaacaacc agactacaag aaacgtatta caaatttgct 114180 tagtcgtgta ccttttgttg ataagaagac aggggaaatc aaaacaagga atctcattga 114240 cgagttcgac ctagatgttg agttcatcat tgaacctaag atatccgtag cactagctag 114300 aatgatgcgt caggttcata agcatctacc agacttcttg gctatctgga acatggactt 114360 cgatatgtcc aagattctag aggtgcttaa gaaagagaag atggcacctg aagatgtttt 114420 ctgtcacccc gacgttccgc caaaatatcg taaggtcaat tatcgtcgtg atgttgcttc 114480 acgtatcacg aataatggta caaataagac caaggctcca caagaccagt ggcatgtctt 114540 tgaagtcatg gcttcgttct atgttatcga tgcgatgtca ctctataaaa agattcgtgt 114600 tgcgaatggt aacatgccta actataaatt ggctactata cttaagcacg aaatcggcgt 114660 tggcaaacta gatattgagg agatgcctta caccgaggat ttgaaatggc acatcgatat 114720 gcagaaggac tacaaagctg aatattgtgc atacaacatc atggatgact tgttaatcct 114780 cttattagat aagaagactt acgatatgca atctgcggtg agtgtcttat cggaatggtc 114840 acctttctct atctttgctt cgttacctaa gcgattgtgt gcagcactaa ctgtttatct 114900 tgaaaaggat aaatgtatca ttggaacagc tggtactaaa attaagaacc ttaatgatga 114960 agaggtgatt ggtttagata actggattgt aacgttacca gcacacaaca cgatggagaa 115020 tggggcaaaa gtcgtctctg aggtgaagag tctggtcaca gctatacgga aacaggtagc 115080 ggatgctgac ttaacacagg cgtacccgct tggttcctct atacttaacc agtcacgtga 115140 aacacgaatc atggaattgt gccgtgtgcg tgatggagaa gaatgggaca gacgacgggc 115200 tggtattaac ctaacctcgg gtaaagttaa ctcaattgaa atcgccaaca ctttcctaaa 115260 gatgccagat attgatgtgg tattggaagc gtttgaagaa cgtaataatg tagactacag 115320 attggagttt atgagaaggc gacgagaaga agaagagttg gccaaagccg aaagagaaga 115380 gaaagcggca taaaagaaaa aaccctaaga ccatttggtc ttagggtaat ctttttttat 115440 tttcttactt agatgggaaa aggtccatta gacgcttagc cacatctttg tcagaaatac 115500 tttcaaacac acgcgaaaca tttgcttctt tgtggatttg tgctttgtct ttaagacgac 115560 cgtacttcga catcagcgtc aagaattcgg caaggaacac acgctcacct ttgtcttgaa 115620 tctgtttagg gttggtcaag tgcttaacga tggtaggtag ttggtactca ccgttcttag 115680 agtcggccac acgttgaaca aatgcaccaa acatcatacg ttgtactttt ggagatgctt 115740 tcaccagagc gcgtaccgcg gcatgtagtt tttggtgtgc tgctagatcg tcagctggtt 115800 gtgctggttt acggatatag cgtgctgcat attcgtccag ttgttgcgtg aaagctttaa 115860 cttctagctt ttcatgcaaa gcgatgtctt cttcgacatt ttgttctaga gtggccgtta 115920 gttgtttctc accctcagct gtttcctgag tgatgacttc atccaactgc tcttcttgct 115980 gaccagccgc ctgctgctct agagcctcac cctgctcaac cgtggtattt tgttgagttt 116040 gagttagttg attatttcca cgtttagaca ttatcgtctc cttagctaat atggtatttc 116100 ggaataaagt ctgctacttc taagtcagag gcgtgcatag cactcattgc accgtacata 116160 gtatatgaac cgatggatgc ctcttcgttc gcaatagcat ggggttcacg agcatagtac 116220 tcgttagcac aagtactaca agtgtcgatg tggtcttgct tacacaagaa tgctcgacgt 116280 aatgggattg ttttaccgat ggactctttt gctaaatcat cgtcaaatgg cactatttta 116340 ccgttgattt tcgcattgag gccaatatag agtttgtagt tctcttctgt gatgtcctgt 116400 ggtaaagctt ctgcgccaca atcaccaaaa cgaactacgt ggttctggaa ggtggattgc 116460 aagaatgtta ccttctcacc gccttttgct gtctctgagc cacgttggta agaaccttca 116520 cgtgtttcgt tgtttttagc aaccagttct tctttcttcc agccatccat taaaggggct 116580 gattgtagaa taaaagaacc atcctctcgg aaagccgatg aagcaccttc tataacgtag 116640 agcttgcgac gacggttacg agccttaggt gagtcgtagt attcgataga ggcgtcttga 116700 gataaccatt ctctatccag tgcatctagc tcatctatga tcttcgccac cacagaaggt 116760 ttatgtaatt cgtgcgcgtg ctctttcaat agccgttcac gggtctcctt cattttaggg 116820 tgggtgccaa gagttatctc agtacctgtt ggggtgatgt aagttgataa agcttttacc 116880 tcaaccacgc cctgaatgaa acgacctaat tctgttgagg taaagtattc tccagacgag 116940 ggtgctttgt catcatccac acctaagtgt aaatggtcat caagccactt atctggaagc 117000 acattaacat tgacgaactc aaatcgtgga ccaaacgcat aataccaaac agtaaagttt 117060 gcaattactc gccccggtga ggttttgatt tctttactat caggacccca catacctgct 117120 ggcaatgtcc accactcatt gactctgaat aagccctggt tttggatagc atcttctatc 117180 ttaatccatt cgccatcttg gtagtaatgc gccaccccat cgagataatt taggtcatag 117240 tcttttggct tgtagtcttc gggtagcaag gccacgttaa agacgcctaa tcgccagtgg 117300 agacttctcc atctttcttt acggagagct gttacaaaat aatcgttacg attcatcttc 117360 ctctacctct gcgttaaagt agcgaatcac accttcacgg atatcgtagt aatcaccaat 117420 accaaagatt tcattttggt ctaggatagt aactaccttt tcagcattac tcattgcttc 117480 gttttcagaa tcagtagttc ccaccaatac cccaatagat agagtagcaa tcatgctttc 117540 cgtcatctcc acagggtttt catcaaagtc aaaggcgttg accatacttt ctggtgttgt 117600 gaaagacata aagctttcaa atacgctata gaaaggcacc tctggattat ccagtaggaa 117660 attaagaagt cgcttaccac gttcagcaaa gtaaacttca ttgtccatat ctttctttct 117720 accaatgatg ttttctttga tgttattaat aaatcgaggt tcgagatgtt caaaaccacc 117780 tgtgtagtca tacgtctcat ccgggaagat gaatagactt aggttattaa ggattatgaa 117840 ttcgtcttct tccgatgacg caatcgccaa taacccatcg atatcctcga acgtttcaat 117900 agcatccaaa agcttaaaca gaccgacaat cgacaacaac tcattattaa tgaaatcgta 117960 atcgaaatgc gcacctagtc ttgctaggaa ctcatcagtt agtttaagga tatgatcttc 118020 aaactgtcga taagcatcaa cagcagagtc attctgatcg gcgatggagt aaagatagaa 118080 caggtcttca ccgacatcgg tatccgatag gattttaact aagtaatgga atgcttctcg 118140 tctactttct gttctcaccg aaaggactgt gtctattaac tcttccatct ctactccaaa 118200 aaataattag tgtattctct catacaaaac caccccaact tattttttaa cgatcatcac 118260 tattatatag aagggtgaga tcacctttaa catatttact tttatacttt ttttcacggt 118320 aaagtcttta catatggaag atttacccat caataaagga ttcaaaaatg tctcgcaaaa 118380 agaaaatttc aaaaggtgac cctcgccgca agttccactt taaaacacca aaagatcgta 118440 agatggctga actgcgcgct taccgtcatt cgatgcgaga actaaaactc gaatctacgg 118500 ctgtcattca attcgccgaa cacgataaac gtttaactga accgaaatta ctgacggctt 118560 ggaaacctga aacaaaggcc gagcatcaga aagttatcga tagttgtagc aacatgatcg 118620 agttagcaga agccacactt ctagttacag agaagtacgt tcttctaaac cgtgaaatcg 118680 ccgctacatt aaccgattat gatgattcac gtttgtacga tctggaagaa ttacgtgaat 118740 tggtaatcaa atcccaagaa gagctgcgtg tggtagttcg tcaatacggt cttaatgaac 118800 tgaccgcaat tagtgcttaa aagaggtagt agaaatgcca gtaagtaaaa aacgtgtaaa 118860 gaaagtcaaa aaacaaggtg gtaatctacg tgcggacttc cgtcgtgatg cacgacgcac 118920 catgcgcaca actatcgcta ctcttcaggg tgttacgcaa atgcgtgaac atgtagccaa 118980 aaactttaag aatttcccta aagaagttct agcttctgta gaaagtaagg aacatgctat 119040 ccttgcagaa atccagttga tggagggtaa agctgaatcc atcattgaac agtgcaatcc 119100 tgactctaaa acaatgcaag agtgggaagt tgatgatatg ccaagtgtcg ttgtgttatc 119160 acaagaactt gaatcgaaat ccgatacgct gatcgctcaa tgtatcgaag ctggcgctga 119220 actacaaatt taacggagat agaaatgtct gaagttgata accaaggggc aaatgttgcc 119280 cctgaatcaa ttgctgaaga gcaaaagaaa gtaactattg aacgcaatgc tgtggactat 119340 cgtagcattt atgagaacag tgctgcattt actggtggtg tgtaccagtc gtttaaaaca 119400 ccattaccag catacagcct gtctgatatg gtggaacacg ttgcccgctg gaaagtttct 119460 gatgagagcg atgctcgtct tgaagaactg acaatgtttg ccacacctga agatattggt 119520 tctcgtatct ctaaacgcga caatgctttg tggggacagt cactacccgg acctaacggt 119580 gaaatgggca ttcgtccaag aaacacttcg aagaatggtg cgttgtccgt tcttaccagt 119640 ttgactggtg gcggtacgca agttaagatg cttatgcctg cctctggttt ctacatcacc 119700 ttctcagccc caacagagtt ggagatgtgt gacttcgatt tctctagtgc attagagaca 119760 tcaattgtgg gtatggacac agctggtcta ctaatgaatg catcgtcagg tgtctacatt 119820 cgcaaccagg ttaacttcgc tattaactac gcagttgata cctcactagt gcataaccgt 119880 gagaacatca gaactgtcat cttaaatcgt ctgaatgagc gtgactatgg tcttgttctt 119940 ctcggcccta tgattgctaa gttcctcggc ggtttccctt acacgttgac ttgttcagtt 120000 gattcgtgtg attacgaaga agataagcgt gttaacctag gtcgtctaat tcactacgac 120060 cgtaaagcac tcaccaaccg acagttagaa attcttgata cctataccga tagcagctca 120120 ttaactgaga agttgtacgc agagtatcac gaagagtttg tgcgggttaa aggctcttct 120180 accactatcg gtaacgatga acaaggtaag ttgattctca attactatca tcctagtatt 120240 caacgttact tctacttcac ggataaatgg gtaaatgatg tcgagtcgag caacaacgtc 120300 atcatgacaa ccatggctac cgaagaccaa cgtcgccgcc atctacaaac acgtgcagaa 120360 gcgcgtcgta tgttgcgtta tcagcatcta atccaaagta tcgaaagtgt tgcacctacc 120420 ggggaaacag aagtagttac tgaagaagaa gacattgctg agattttgcg tggtctttgt 120480 gcaaaccctg agttggttaa aatggtagag gtggatatcc aagagttcat tgtcaactca 120540 tccatcacac taatcggtta ccgtgctcaa gagtgcccta agtgtaaaac aaaaccaact 120600 gctggtaatg agttcatctc catgagtccg gactcggttt tttttatgct tgttcaattg 120660 gtatcagaaa cttacaaggg tctagcaaat ccagacgtgt agtcgctcac cttggtgaag 120720 accacactga agaccttcat cgtttgatta gtgtagatac gaggaaacta tttactggtg 120780 aatcggatat accaatctct cacgttgaag gtcgtctctc actcagacaa tgttacgatg 120840 cctcatatgg tttagacact ggcccattcg gtatcgagat gactgatgaa gagtcccctg 120900 caaaattcag tttgtacgag tactgggctg aaatacatgc aagagaacga atcttccatc 120960 actacggttt ggatttggat cagtttctaa atcgacctag atacaaaata gaaatattag 121020 ttgataaggt taaaccgctg aacaaatctg aagagacgac agctgctaag attcaagatg 121080 agataaaacg ccaacttgaa cagaactcaa aaaataataa gatttaggct agcattgcta 121140 gcctaatttc tttttttagt gtggtactgc caaacgacct gcttctaacg attttgttat 121200 aaactcaata gttaaagacg ggttatcttc tacgttggtt ggtgtatcat ctttaataag 121260 atgataattg aagatttcgt agccgtgtgt tccacgtatt gtactgccgc gtgttacaat 121320 gtatttcatg ccacgttgct ctacttggaa gctaaatatt ttagccttag tggaatggtc 121380 tagaagcgaa gctaggtttg gtgtagatgg ctctacaagc ttctcaagcg attcttctaa 121440 actagggtac agtttcagct tttcagataa gaactggtag aagctttctc tgagagcttt 121500 aatatcacgt ccagggacca ttatccttct cctaattcaa gtacaaaaaa agaaggtgat 121560 ttctcacctc cttcccttct tacgcctatt gtttctggca ttgtcacgtc tattcttcca 121620 ctcgcgtctt gcctgcttat gtttaaaacg tttcaatgct ttagttgcct tagacctatc 121680 tggaagtttc ccacctgcta cctctggcga tagcttgtag tttaccttct cattaccttc 121740 gatctgatac ccaccattaa ctatgtttag acttttcgct acgtggctta agctatccat 121800 acgttcctta agataagtat tatgcttatc cagttcacga caatgtaaga ataagacttt 121860 tggcgtcact ccttcccatt gcgtaacagt tctagggcgt ccagcaatct gttcgttctt 121920 ttgtctgtca ctaatagctg gtgttactag tgctagaaca agaccgggta agtctatcgc 121980 tgtgcctgct ttctctggtg acgagacacc aatatcggct gattgcaaat cctcaaactt 122040 atctttatct acataccgca caatattgaa ttcaccttcc atttctaaag cgacgcgttt 122100 ctttaaaaac tcagtgaagt ctgtacaagt ttgtatcatg gagaaaaaga ctaatgactt 122160 ttgtcccttc tgataattat tgaagtaagc acgtttcatt aaatcgtaaa ccatttcaaa 122220 gtaatcgttt atcatctcgt gttgataaag atactgctca aaggtcttat gattgtacat 122280 cgacatgcca ttgacacgat tacgcatttt cttaacgaga atgctataat agatgaaggc 122340 aatatcacac acacgaatgt atggtacatc cacacgatta tgttgaggga aacgttcagc 122400 gtaacgaagt ctatggaact ctttcttggc tgatggtttt aacgtcgctg acatctctac 122460 caattttggt gggtttaaga taacaccact caaatatacc gttaggaagt gttcatggat 122520 ttcgtcataa ccgacaagcc ccgcaccgat atattcgtaa aacttatgaa gctctacacc 122580 attacgatgc acacgattgg agaattcctc taaccacaac attaatgagg ttgttgggat 122640 gatgattgtc gatatatttt ttctatctaa ttcaccactt ctcccatctt cgattaggtt 122700 atcgatacca gctacgcctg acacaacacg tactctaggc gatggttcat acaaaccacc 122760 ctcatcatca acacaatcgt atttccattt cttaacatac gctggtctaa cgatgataac 122820 ggttcgtctt ccaaaacgaa cctgcacttt ctggaacgtt ttagttttac cacgacccgt 122880 ttgaatctca aaaattgttt gattgttccc gggctgcaat gctgtgtcac tgacctcatt 122940 ctggaagaag aaacgtgact cctcgccatg tacacgcaaa tcgaacttat agttcttgta 123000 agtgacttct gcaccttctg ctcttggtgc ttcgacaatc tcaacctcac ccatcctccc 123060 ggcttgttga gttgcctgca cacacatttt aacttgttct aaaaaagaac ggtggtaata 123120 atagctgttg gcttgcttgt cgatgtagaa gtatggtctt ccattaccga cttgccattg 123180 attgtaattt ctctctagta ctggctcata gagtgtattg ttgattttgt ttgaaagctg 123240 attagctaaa taagggcaag ggtcatgtac aatcaaccct tggcttaaca atgtaattct 123300 ttgtttggac atctaatccc cccaatatcc tgtaggtaca catatggtcc taaagggggg 123360 acgaatcccc catgtttaga ctttcggtat ataaaccgcg ttatcaagaa gtgaattgtg 123420 tctatacggc gtaacgaatg tacgcggcct gtaatagata tcattctgtt cttggtagac 123480 caaatatgga cccaaagaac gttcttccat tagcgtggtg tgtttatcaa accgcgcttg 123540 ggaattacca aaaccaccaa ccaatgatgg gtctgattca ctcgaacgac gcaaagatgc 123600 gagaatagtc gcaatgtgcg taatcggtgt acctggaagt ttacgttcca aatacgtgtg 123660 aacagccaac atggcttctg cacaaccgtc tgctgtcgag ccatcgtaat cagttatcat 123720 gctataacga ctgttagatt tgctagaacg cagaatgttc tcaaggttag ttacgtagac 123780 tggcatactt tcgtgacgtt gttggtattc aaacaacgct acgtttcgca gcttaccatc 123840 ttgtgtttta ttgaatccat ctagagaaaa ctcaataaat ttttcgttgg tatcgtctat 123900 aataaaatct ggattacggc gcaagaagcg gaagaattcc actgttagcg aggctggaac 123960 accagaaatt ataccttcga actcatctga cactacacat tcaccatcag gggaatagta 124020 atcaacccag tattttgtaa tgctggatat ctcaccaatc tccaacaact tgagattgtt 124080 tgtgtatgaa agacgcgtga agtttggaag ctcttcacgt agaacgcgaa gacgtgcaaa 124140 ttgtaaatct gctttcgctt ttacgtgaat acggtttggt tcttttggta cgacttcaaa 124200 tattcttgat tgttgttggt ttaggacaac acggaatagg aagataatga agtctaggtg 124260 cttaactgat aagatactct gagaagctcg ctcagtcacc gtgatacaag aaacatgtcc 124320 tggtgaatcg atgtcaggga tattgtaggc caagtcaccg taacactttt cacatatacc 124380 ttgtttcgat agatgattac atcctaagga agttctaagt ttaatcgtct gaccgataag 124440 atgaactgag tctttctcta tcaactccca ttttttatct ttgtttaagt ggtaactgcc 124500 aacacagcgt tcgaataaaa ctttacctgc tttgttgtta gctaagttta tctccaatac 124560 ttcacgacta ccacaatcac ctttgtataa cgtagtgata gccgatgtta gtagctgcat 124620 ctttctcgag aagtattctg agaaggcaat gtaaccatcg ttgtaaacga atgacttagt 124680 cgcagaagta cattctttaa caaagtcagc aatagtacta aaaccagtac cgaacccgcg 124740 tttaattgcg cggtcaaaga taactgagtt tacctctgtc gtacggccac gcaacgccat 124800 ctgcaacgat tggttcattg gaacagattt gttattcgtg gttacactga taccgttgtg 124860 tggatacttc ttagtactta tgacatttcg gattgtgttg tgagcatggt ctatactttc 124920 aacattatct gttaccttgg acagagcttt cttaatctct gggtcttcca gtagctgttc 124980 tatgtcgtca aagtcgatgg tgttggcata ttgtggtaac tcagccactg ccaggttgta 125040 cgccttattg taaatgtaac ggtacgcgat agcccaaaca tcatacttgt caatctccgg 125100 gtaatcacgt gtcaccttaa ttgctaagct aatgagctct ttgtgtgtat cgtcgtttat 125160 ctctcgatgg taatcgtagc agaggtcaga tggtattttc acctgattat aatgacgatg 125220 gatagcccag taaggccaac ttagcaatat gtgtgatgcg tgaaggggtt tttcaacccc 125280 atcactaaac ttaaccaaat acttggtttt gttttgtaca acttcttcat agctaaaatt 125340 agccaattca tggatactga ttttctccac tcttttattc ctcttattat tccattaact 125400 attaatagct tgggtctgat acatctactt cttccaagcg tagtttctgg agttcaagcc 125460 cggcaatatg gtgagtgtgt tgtaggattt gatgtggtcg tgaatcacct aaaggatata 125520 gttcacgatc aaccgcacat tcaatattca tgggggtagg gtgagttaat accatgtaat 125580 cttgcattcg tgcaacaata gggttattgg ctctatcatg acattctgct gcaagttcac 125640 cagcaccgtg ttcagccagt aaacgctcct ctgattctga aatccactta catgctttgg 125700 ttggtgcagg acgtaagctg atttcatcag agttggtttt ggcgattgta ccaaatgggt 125760 caaagcgaca agaagaaata ctggagaatt cacggccagt tttgtttaga cgtatggtat 125820 acacgtcacc gatataaaat tctttttcag tccaaacttt ctcaccattt ggtttggtga 125880 taagcaattt agatttacgg actttgtact tctcttttaa gaggcgagct atttcataaa 125940 agcttttctc gtaatcattt ggtatccagg cacggaaacg aacatcacgg atttcctcat 126000 aaaggatttc acgttgttcg cgcttactgt gagtgtcttc tagtacatcg gcccactcag 126060 ggttgaaatc tcttgctaac tcaaccatca aaggccaagc tgcatcaatt cccccttcct 126120 cgtatgcctt cactatttcc tgactcacaa cctcgcgggc agtgtgcgac atgaatatta 126180 cgtagatcgg taaataagtc gaacgacgta aggttgcatc agctgcacgc atacagtgaa 126240 cacgattacc aaattcatca attggcatat cttcaactgg cattatttta gaaacaatac 126300 ccttagtacc acttaagtca gaaatcttac cactctttgt tagagggata ggatagcgga 126360 ctgtaacttc gattcgataa gtttcgattc tttcgaatgc gtagttttta ttgtagttca 126420 aggtttgaag atgacgagag aaatatttcg atttctttcc cttgcccatc aagacatgag 126480 cagccatagc gatagcttca taaatgaaac gtgtcgcttt acgagtgtaa gggatgtttt 126540 cctcaccgcc gtattctttt gctaactcga tatggtaacc gagaatattt tcataatact 126600 ctcttgtttt gaatgcgtgc tggtctaact caagctgaac acgatctggg atgttgaact 126660 ttggtaatgg tgacgtatca aagttctttt ggtcattacg tataaccttt acatccacaa 126720 ctcgtgcacc cgattcacct gaggcatcac catcattgtg ttggatttta ttgtaatagg 126780 caatggggtc gaataggtca ccatcagata attctaatgc tgcatcctcc tcactccact 126840 cgataacacc aattactttt ccgttttcac cgatggaatc accgacacga ggaacatatt 126900 gtggttcagt cgccgtgccc attatgttag ccaacgtttg accattcttc aggctagtca 126960 catatttctt gtaaccgtat gccatgaatt ccccggcagc ttcatttgac atggtgtatg 127020 agtcctcaat tagactcggg tcagaaatca ctactgttgg tatacaacga ccaaaagcaa 127080 actcaccgtc tttaaactgt ggtgggtgat ttaagttcat ccccttatat acaccgccac 127140 ctgatgagcg caaagcttgt ttaccatcat cagtcaaagt taattctgag gcaaagacat 127200 cgtcgtgttt aatacgatta tgaatttcta atacatcaat tgcctcacca tcatcactaa 127260 aacttctgac gaaaattgct tgttctaaag cttgatagtt acctggacta actcgtttga 127320 agacgcgtag ggttgttcca tcaactaacg atttatcatt gaaaaggtat ttgccatatt 127380 ccaattcatt accagttggc cattgtacta cttctggatt tatgataggt gcagtttgtt 127440 taatatgacc gcccaccata ctcacacgca taccagaaat ttcatctggc tttgaaatca 127500 ggttagtggc tgtacccact aactccggtt ttagttcggt cgacattgat atttcctctt 127560 tatttctaag tcaccattga tataacatat aacttaatat tttttgcagg ggttttgtat 127620 gttagaaaaa ttctacacca aaagaatgga tatgtttcct ctggagccag acgtatattg 127680 gcgacttatg agacaacaca agttatctct aatagaagcc tctcaggagc aagtgctaac 127740 tgaaggacta tttaccccct caaagtatag cttctaccgt tattttttaa atattgagtt 127800 agatgctaaa ttatggatac ctactttggt ggcttctggg attgataata tagaagacta 127860 cgttgatatt aatcaggtta ttaaaatacc ggatatttca gtggtcgagt ctattatctc 127920 ctcagtgaat taaaaaaaga aagtagggcc gaggccctac taatctttat tttttatcgg 127980 cgaccccaac gggaagcgcg ttcgttacga ccatgtcgat catcgttgtc acgtgagaag 128040 gatagatatc ctccacgacg atctcggcta cggcgtcgac caccacgacc atagtcatca 128100 tcatcgtaat catcacgacg ggatggacga cgctcatctg tatacaggcg cttgtctagc 128160 ggattgccag ttgaacgtgg tttatcatca cgaccgccac gatattcaga acgttgacca 128220 aagatagcca aaccctgtgg ttcatcatct tcgtcttcgc gttcatcaac atacttatca 128280 cggcggcgat tacgcaattg ctcttcacga acttcttcga catcaaaagg aatgtcttct 128340 ttctcctttt tcttctcgat ggttgaacgg ccagtgttac caggtagtgg tggaatacga 128400 ccacggtaac tgctgacttt atccatgtgt tcagcaaaac ccaattcgat aactggtaac 128460 ttgatgtcct tttgcaccat cgcagccagt ttattgtact gatttgcgaa cttaatgtag 128520 aaggacatca atgcttcgaa gtttggagca tcaccattgc taccgaacat gtgggaatcg 128580 gagccctcat gcatcagtaa ttcgcgcatg actgcaacga taccgcgttt acgtgcttta 128640 ctactcattt gaacacccat taggaaggcg tcatctagat caacgtcgaa ccagctagaa 128700 gtgtagtaca aaacacggag ataatcctca ccagcaatct tttggttacg atcgacaaac 128760 aagcggaccc agtctttcac atctgcgtgc tcagtaagtt ttgtccagtc tttgattgtt 128820 ttatcatcga catcgttttc gaacttagcc aagaactttg cataggtgga tttcttttta 128880 tccgcagaag cgcgaagttt aaagaatgct tcagctaaaa gaattgattt ctcaataatg 128940 ttagctttga ccattttggt cagccattta aaaacttctg actgatctgc tgttacagac 129000 tcacataacg ggaagtatgc atacttatcc ccccagtcat tatcatccaa aactgcatta 129060 gttggtaaaa ccaacttgtg ctcgtcgata gttacaggtt tctcaccacc gggtaataga 129120 accgcttgtc cgtctacaac acaacctagt gactctaggt tgctagttag aaattcaagt 129180 accttcactg tttattttcc ttattcttaa atttgattaa tcgcgctcta gtaggcggcg 129240 accgaaactt ttcttagaga agatgtcatc taaagttgtg gtagcacgac gtgggctacg 129300 atcactgcta gggaaacctt cttcaaactc ttttgcattt cgttgtaaga ttgctgtgtc 129360 aatctcttcc cgaacattat ggtattcctt aacagtatta acaaatgaac gactgcgtgt 129420 tttggttagg tgtgttgcca atcgaccttc aaggaaggag ccaaatgtga aggcaatgac 129480 ttcaccctca tcatcataat cgatttcaac gcgcgtcaaa cctgacaacg tagagtaaac 129540 agtgatctca accgggattt caccgttacg ggttaatgga atgaaaactt catcgacgaa 129600 actatcttcg aatcgatcga ggaagaattc tgggacatca ccattcgctg ttagagtttc 129660 aatgttgtaa ctatcttcgt cgtgtgcgtt agcatcttgg aagaattgaa actctggttc 129720 aacacgccca gttgaacgcg acgagtaaag attcgataca cggaacccac aacctttgat 129780 gaggttattc atcattagct ctggaatacg atgacacaaa tcatacacgt ctagcgttac 129840 ttgacgagcc gattcccaac gttcagaatc ataatcagtg ttgtcaaact catacacttc 129900 gattagattc attgcttcgc gttggctacc agaagttact tcaatgatat cttctagagt 129960 aaatgcattt tcgcggcgca gatcttcgaa actctccaag tctgcatctt tgagtgcaag 130020 tacaaagtca ttatcagcaa cgcttgactc attaccttta gatttgaaac gggaagaaac 130080 gaaagagtta cgggatgcgt ccatgtttag accaccgtaa gttgcttctt tatcttcctt 130140 acccatcata tctgcgtagg ccaatgttct gaagtagtta tctggtaaag acaaattatg 130200 tcggacaacc ttggcagtgt tgccatcttc accaaccaca attgagtctt cctcaacatc 130260 gtgtccatct gcatagtcat caacataatc agcaaaggat acgggtgtag agaacttctc 130320 gtttttacgt gagtggcggt ctggtaagat taccagtcca ttactaacca ctgaatactc 130380 atcctgcatt cggccaccgc gtgtttcacg tgtagttaca cgtaaagtca acagcgaatt 130440 gatgtgcatt acagtgtcca aggtaggttt accacggtct aactcggcac ggtctgtgta 130500 gccacaaacg atcatttgca atctagagtt tgaacgaagg tttggattct cctgttcaaa 130560 cacagccacg taacgataaa tgcggtcacc accacgaagg taacgcgtac cagaatctgt 130620 attacccagg atgatgtttg gatcgtaacc ctcaacatca aaactagcca tacgacgaaa 130680 cacaccttta gcttctggtc cgtcgaaata gttacgaccg cgatcacgta caccgtcgcg 130740 cacatcacgc aaatcgtgta cgtttgaacc ggatgtattg atcttcaaat tacgacggat 130800 ttgttttggt aggttaccta cttcgaaaaa gtcaattgaa actaaatcta gcatgtttta 130860 aattcctctt actgatcaaa attatttagc aggtgcggtc atggctaata gctgaccaag 130920 ttcatttttg aaatcttcag ttgggctaaa tttaccgttt tcggttccta ataagccaca 130980 gatttctttt gaagctttct gctcccaaaa gtactggtta aggtagttcg tcattgcgtc 131040 aatagacaga acgtagggtt ttacccaact agaacctctt ggattaggga tagagtttgt 131100 gtaataacga tccaaaaact ctattgtgtt tttgtctagc ggttttacat taattcgatt 131160 gtattcaatc tggtcaccgc tacttttcac atctttcaca tcggaactca acaatcgcgc 131220 taaacctatt aatttatgct cgattagata aatctgagtt aatccaacta agtgtgtgat 131280 taaatcaaaa gatatatctt gtattgtttg atgcatgaca tagcgacgaa gtgctgcacg 131340 gatgatgaag cgatggactg gtgtaaattg gctatatgga ttcttttgtg cggaatcgat 131400 agctgcttta ataagagatg gtttagattc aatacctaaa gcatgtcgtg ctttacgata 131460 gtctaaagcc cacacaccat tcatcattgg tatcatatct gggacttctt gacgtgattg 131520 atacgtctcg aaatacccca tcttactgtc ttcacccatt gccattttct caccagggcg 131580 ttcatctgtg atattgaaac gacgaataat ttttttcgtc agctcatcac tgattttatt 131640 attgaccgcc tttgcgaggt tggtttggtt actagttatt gatgttggaa taacacctaa 131700 aatgataccg acacccatca ggtattgtgg aagatcagca gaaccgatgc catcaagaat 131760 actaccgatt acattagaac gcttattctc aagtatcttt tgagatgtag cttcgatata 131820 aatttgtagt ctctcaaaac catcggagtt acttatttca caatcgtcta acttcgccat 131880 gaaagctaat gccttaaaca tgaccgaagc accttgtcca gttttctggt gttggaacat 131940 accttccatt gccaagattg gcataagagc acgcagacga actgctaata tagccagttg 132000 tctatattct ccacgggtat atgtttcctc aaccgtatag tgtttatgtg ggatgaacac 132060 ctcggttgca tttttaggat atgcgatatg gtcgatgtgg tcgatgatgt gttcttcagg 132120 atgcatttca tctaaaatgg tgcggtaaat tttcgcatcg atttcgatat tgcacattac 132180 taattcgtgg acttgtttgt aaatgtcaaa cagactctgg gcttctgttt cagacagtga 132240 actccaatac gaatttattt ctttaaaagt accttcggtg cgtggtccgc ggaattcacc 132300 acagtataat tcttcaccag cgtttgatac aatcaaagaa gaactttgga taactatctc 132360 catttaagaa tcctctttta tttcgtttta ccactaagat aacatatatc cgttattatt 132420 ttaaaaggga ggagtgtttc cactcctccc ttttattact ttttgtatct actgcttaga 132480 aatagttatc tacgctagta gttggagctt gtggttgtgg ttgataaccg ccgccattac 132540 cgccgccata attaccgccg ttgccgccac cgtaattacc gccgccatta ccgccatttg 132600 gattgaatgg ttcatacatt tctgccaaac ggtcaattag gcgatgttgc tgagatgccc 132660 atgcacgtgc atttcgctct gagctttcag ctactgacat ctgaccaccg ccacgtttca 132720 ttgggtattg tttcagtggc atccaacgaa cttcgacaga tttaccttgc gattcaagga 132780 ttgctacgac cataccttct tggttacgct gcacagttag tgtggcgtgg atagcacctt 132840 tacgctcttc tgcaatagtc agtggcacga actcacgaga ggctgcacat tctttaacag 132900 catctacgaa tgtttggaat tcaacagtcg gaagagacat attgatccat tgttgtttgc 132960 caaccatcat cgataaatcg atagtgttac aaccacggcc gcggttctga acagccattt 133020 tcaaaccttg ctgttggcct tgtgaattgg ctacagtttt tggtttcatt gtacgatcgt 133080 tcagaaagtt ttcttgtttt actaaatcta ccatttggtt aaatccttac taagcttagt 133140 cttcccacaa gatatgttcg gggcgttatt ttttaagttc tcgaagtagt tttactaaat 133200 gtggctcgta agcacgctta acagcctcaa taattcgagt gtcagaggtt ttataattcc 133260 acttatactt cttggctaat tcaagaatca tcttgcggaa cttaattggt tgtggtgcaa 133320 ataccacgcc atcaccaaat aaggtgaggg tcattttact gaatggaatc atttcaggtt 133380 taccagtcaa cttactagtc cactcagatg gacctttgac tttacctgtg tgagactcca 133440 gcaatgaaag cgaagggaag ttttcaacgc taagtaaatc aattggatgg tgggttaata 133500 acaccgttgg tttacttgca ctgatatcga tctcatattc agttacttcg tggatatcac 133560 cgatgacctt ctccatattt ttgaagaagt cttcttctaa tgcacgatag gctttttgtt 133620 tgtctgtcgt ggcattatag aaatttgctt tttggtagcg gtcgttgatt ttcttgtacg 133680 tacagtaata gaaactcacc acacaatctg gttcgacgga tttaagagtg cttaaaatcc 133740 catccatgtc ttcacgcaca ctatcgatta atggaccaat agtcatccga ttttgaagtt 133800 cagtggggaa cgcattcatt gcgtttcgaa acagagtgcg aagattaacc atcagcaact 133860 tattgcgcaa agggaaatct tttgcattgg catcttcata ctctcctgtg tgagtagcac 133920 cttctatcgc caacgatgtg gcgatagaga tgttatagat gccgaagtta cggtcgtatg 133980 actttatcat agtcgttcct cgatctcttt aataatgcca ttagcgatag gcgaattgct 134040 atttattctt tctagcagga ttcgactgat ggtatcttta tctaaatgga taccctcgtc 134100 tgctttttcg ctaagagctt tattgatttt gatgatgcgg tctttattaa ctaagcgttg 134160 tggttttatt tcaataccgt aacgttcaga tagactgcgt aaagtaactc gaatatcact 134220 atcgtgtggg taagttactc tcaacttacc atgtttgctg tggggtgatt tctcaatctc 134280 cttaacagct aactccacac ctttgatgat ttcctcgtct gttttgtttt caccattcac 134340 ggtaatgtaa gggcatgggt gagggttatg gacaaaccaa ccctctgcgt agtcgtcgta 134400 aaaatctaca acgtgtacac cttttgtacc aacctcacca tggctcaaac aatcaggaga 134460 accagtgact ctgattatac ccttttgttt tgatttatga tcgtgaccaa tcataatagc 134520 caaacgaaca aatgacatcc attcgtactc gtcgaagttt gcctttgcta caatatgtgg 134580 gatttggaat ttaaacatcc catgcatacc agccaagtcg attttactgt accctttcga 134640 tttcatcaaa gacttaaaga gttttgttgt ttctgctgca tcatctcgat attcgtcagg 134700 aactaaacca accactttgt ttatcttctc atctttgaat acagtgatat catcgaagta 134760 ttttaaatca accccaaact ttttattaag ttctaaaata acacggctct gtttacggtc 134820 gtgttttggt gtcccttcta aaacccgcaa tgccacatct ttctttttac aaagttcgag 134880 taattcgttt aagaaaccaa ttgccttgat cagatcatcg ttttccaacg tatctctttc 134940 atcaaacaaa tcacccaata tatagatagc atctaatggt gtctccaaaa catacttaat 135000 taacaacatt aggttgaaaa ttataacaga cgttggagtt tgtttatgca atagatggac 135060 atcgctaaag aacaacactc tagaagcgtg tgctgattta tgtggtaaag tgttagatga 135120 ggtcaccgtc cacgcgttga tcttcattct taacttctac cttatcttct gttgtgtttg 135180 agactaccgc cttgttacca tctaccagtg ttttatcgaa aacggtaaag ccattctcgg 135240 agaaaacata gttgatttga tcaataaagg tatcgtcaac accagtgtca ggtagacgca 135300 ttgaaatcag ttcttggatc atggagtcaa aagaatccgg gttatcttgt cggttcaaag 135360 ataactctgc gtgttgtgaa ctgaacccag ggaattctgg atcgtctgtg gccaacgttg 135420 gttgtggtgc atgtagtggt ggaatcttga tgtagacttt gtcaccttgc ataacatgca 135480 tttcaaggtt ttcaccgcca caataagtaa tccagtgacc cgggtgaatt tcttccttca 135540 ttacaccgtg taacaatggt agaccgacac gaatgaaatt atcgtagtcc atctccacat 135600 ggttttcgtt taaaaaacgt aacatttctt tttcactccg tcgaacgtaa tcagttagag 135660 ggtgtccatc ttgtaaacta gccatgagat aagctcctta gaatttaaat tcgtagtacg 135720 tttgttcgta gtcattaaaa aagtcttcag cgttagtttt taggatcgtg gccagatcat 135780 aacttttgtt attgacgcga atttcagctg agataaatgt actataacgc ccatcatcat 135840 cttcaacata ttcacattta actctcacat ccttcccaaa cgaatatgag aacaaacgcc 135900 ctaagtcgtc ttgtacccga ttacagaact ggtccgggtc atggttagtc tcttgatagg 135960 ttttaccaag agagataatg ttgtctttaa aaataatgct ttggtcagcg ttaactgcgc 136020 gatacgccat cattatttct ttgactttat cttcaacaga tgtggcccat ccattataac 136080 ccatgcttcc aactaccttt tttaccatta tagtaccctc acaaagaata aaaaataaag 136140 cacgcccaca aatggggcgt gcactgatgt taccctctca tagcattata cgtagaggtg 136200 acagcatcat cagtttccat catcacgcgg atttgttcac gccatgtggc ttgaatatcc 136260 aaacgttctg aacggctaag tgatcctttc tcttcgctat ccagtacgta tgagtggaat 136320 ttattttctt cagtatcgag ataaccgtcc atgacgatac gatagtttac atcggtatgt 136380 ttcactgcgg ttccacgcca acggtcacgt ttagagaaac catcttcata acccggctcc 136440 atatatcgat tataatttcg acgtacaact gggttagcga ctaggtaact ttccataact 136500 gaaggtgcga attgcaattc accaatacca aacaaacgac gtactgaatt tgacttacgc 136560 gaatgtctta aacgacgtaa agcagataca gagttacgat acagagagtt tgctcggatt 136620 gaacgactag tttcggcaac gccagctaag aactcttcag agaagtttct ttcgctatag 136680 cgtcgtttca aatgactagc gctgtggcca gacaaccgcc ctgaagctat gccgctaccc 136740 gtaccaacat cccaaggatg tgttcctgta gtcatattta ttactatcct cttcctttaa 136800 atattaatca tcccactcac tgtctgtcac cgttgcattg atgaatccag attgtaaaga 136860 gatgatttcg gcatgtaagg ttaacttttc actaactgcg ttagttttac tgcgagacat 136920 gatacttaac gcacctttta atcggttagc taatcgtctc atcagattat cacgtggcat 136980 cataacctga atttggtcac cgtcgtaatc agcgttagcc tgcttgataa ttaacggtga 137040 taggtcaata gaaccatcat tgacatctgt cttcacatct gtgatgtaaa gcacccatac 137100 tgatagacgt accaatgtag ggttacgtaa tggtacaatc atgatacctg gaccaggagc 137160 ttcctcaatc agttctttaa tgacatcatg aatgaatggg tcatatgtca ccaaagctcg 137220 atctattgtc ttgattgttt ctatcggtgt aagattatgg gtgtggagta gtttattggc 137280 aatgtctaag taaagtaaat ttacagtcca acgccagggt gttttagagt ggtcgaattc 137340 atggacacca gtttccgaag aaattgttgc acggccagaa tacgatacac gcgtactatt 137400 gttctttgaa cgtgcaatgc cctctttagg gaaaacgaca tcacgacgaa actcaaagtt 137460 aaagaacgca tgggttctgt tagcggtaac cattctagat tgaattatgc ggattcgatt 137520 ctttctagat gtatggtagt acgcggacag gattgtttta gctgcatcaa tcatacccac 137580 gtagattcta tcgacgtttc gttttgattc agcctgccct tcctcacaca aaaccaattg 137640 gtctgaaatg atcggtaact tagttgggaa aaacttacca cggtgccact ttatgaatcg 137700 aatccaatct tggcgttcta tttcaacttc agtggtttcc ttttttcggt tcaacatctt 137760 gctggataat tgaatcgcat gaaaggtatc gggttcaagt aaccgttcaa ataaccaatc 137820 gaagttctca atgaagctat ttaacccgcg ctcatatccc caactaagaa ttagatcctg 137880 tagggctacg ttaccacgcg aaggttgttt ctcaggtttg tatcgtgggt ctgtcaacca 137940 cgcgaccaaa tcataagact tcatcgggtt attcttaggt agtgtgaaac ttgaaaaggt 138000 acttaggata ttcatccata atgttggatg aataaatcca cgcattgggt aaatggaacc 138060 tatccaacta cgtattctga ttggttgctc taaagctttt acacaaacag tattgcactt 138120 ttcacaaacc gcaccgatgt cggcgtcgta ttgggttgat agatgaccac acgaacaacg 138180 aggtgtggtg ttaaaactgt cgctagatac ttctgtcttt aatatctttg aagcatagct 138240 cgcagcatca ggctgattta gagtttgtgc aatctcatta atcagtattg tttccttttg 138300 ctccgaatac aacttatcta ggtcgacgag agtcatggac acgccataat atccctcagt 138360 gtgcattcaa aaaccctctt tacttttgaa acaaaaaata aaggtcggga aattcccgac 138420 ctttactaac cagctatcta tgtcgattaa cgacgtagac ggccgaaacc acgatctgaa 138480 cggtcacggt aagtgcgacc agaacgttgt gagcgtagag aaccacgtag ttcaccacgt 138540 acacgttgtt tacggtcttc acgtacacgg cagtcagagt aaccagccat ttcaacttcg 138600 tcaaagttgt cttcgattac cttgtatagg aactcgatga actctgggtt gatttggtat 138660 tcgttaccga taccgtcgat ttgaacagaa gttgctacgt tgcttagaag ttcaatcaag 138720 aactctttag aactttctag gttcatctcg cggttttcta ggctggttgc agccaggtat 138780 tcaccgtaga catcttcgtc acccgcagca atagttgcga tgcgcgctag gtcgaagtct 138840 tcgagagtac gtagttgacc atttgctttg taagtaccga agacgtgtgg tacgatgttt 138900 tgtacgatgt cttcacatgt gatgctggat acacctaggt gtttttccag agctgcttcg 138960 aaaccttctt caaggttttc accagccgcc atcaatgctt ccaggtagtc ggtgtcaccg 139020 ttaccgattt tagccagaca gtgaacgata ccatttgcag tttcaccatc gcggtgtaga 139080 acagtcacgt aagtttcgcg agtcatagcc atttctagct gttcgcggat cttgttcgca 139140 ttgtccaatt taccaacttt gattgcgact ggtagccaca tcttatcgat aaccgcacct 139200 aggttacgag acgcatctgc tgcaaggtct tgagtcagta catccatcca gctgttacgg 139260 ctgtggactg ggtataccgc accaagtgca agaagaccgc gctcgtagat attttcttcg 139320 gaagaagaag tatcaactgc gttgatttgt actttagcag caaactgctc aggtttgaac 139380 ttagctggat caccttcgta atcatctggg tttttctcag gaccgacata gtccatacct 139440 acgaagccga agatttcggt gcgaccagca tctgtttcaa cgccttcttt taccaggctg 139500 cgagagaatt tcttgcgacc gttaccagaa gcttggttta cttcgatgcg gaagtctgca 139560 cgatgcagag ttgaagtttc ttcgatttca ccgacttggg ttttgaaggt tgcgctgaag 139620 ttagggaacg cgttgaagtc gaactcttct tcagaagaac cagataggtt ccatgccagt 139680 gtagccaggg cgtaagtaag atgacgcact gaatcttcag taacgttgaa gtcacggttc 139740 aggatttgcg catcgatcag gtaaacgtca gattcgttac agttcaggtc ttcggagatt 139800 ttctcacgac acaagatatc gaactcttgg tcaagcatgt cgtaagtgaa gactggtttg 139860 tcgttgttat ctaggcggta accaccgctg ttgttttcga agataaccgc tacagcgtac 139920 ttttctttgt caccgttttc gataccgatg tagttgatag acgcagagcg tagatcttgc 139980 acgtgaccga aaatcaaatc accgcgattg tctttggtga tttcagccag gattttgttg 140040 aaggtagcag aacgagtagt gtcaccttcc atacctagta cgtttgagat acggcgagca 140100 ggacgacgag tctcacggcg ttcttcgcga cggtcgtcac gttgttcagt ttcgcggcca 140160 gttttgttag ctttgttgtc gtcgatttgt ggcatgattt ttttccttaa tttgcaaatt 140220 taaagttgac atagaacagc ttttgtcacc attctcacaa ggataatata tacccttagt 140280 tttttggaat cggtgccatg gatacatttc tatgtaaaga catataggag aggaataatg 140340 tctaatttat taaacatcga tactgtatcc aagggcaggg tcacagaccc ctccttcata 140400 gtattggcga acaacgtaaa aaagtacagt aacctttttc gcaatcgtat cgcggatcag 140460 aaccgtttta tcccgaaaga ccatatcctt tacaaagtat tgcttgaact aggtcttcaa 140520 ccttatatgg atgacgaatt cctacattat cggattcgtg ataaagcaaa acagttagct 140580 actagcttcc gttttaccta ctacaactcc tttggggagt taagttatgg taactttata 140640 ccagatacaa aagaagtatt gattcttaca acagatgaaa aaggaccaat gactcgaatt 140700 ttgtaccaca atcatttcaa tttaaacttt gaacttggcg aaaagaactt tcacgatggt 140760 ttagctttca tcgaattgaa catctacgcc ttagccaaag cttatttcaa atgggttaaa 140820 gaacgtgggg aaaatgatac aactcataaa ttcctgtaca tggaaggagt ttatcgttta 140880 ctaccagaat atatggactt ggcgttaatt aatagacact tctataatct ggaagaaatt 140940 gacctcccga tggaatcaaa gaacaaggag ttcgcaaccc cccacatagg ggagagtgtt 141000 actacacata taaatactat agaaaaattc tacaccagtc gagactttga catcggtggt 141060 tttttagata atatcccttg tgtgtttaaa gaaactgctt taagttatgt tccaaccatc 141120 ccatcatggg ggactgacca gatacgttgg gcatacgagt tggcaagatt gcaattcatt 141180 aatagttccc tacactattt gatgaaacgt gagcttggta agaaggaaaa gaatcacttg 141240 taccaattcc agcgcttcgt taaaaacttt aaccaatcta gacagcttag cagaattaag 141300 aaagaagatc ggacttacct ttcgccgatt atcaacgaaa ccgatcttct actctctaaa 141360 ctactttagg ctgtgtaata gtctgataac agacgagtac ggttgtcatc tatcatgaag 141420 acaccaaata cttctaagat gtggtaatat ggttccacca tcgcaaaaac tgtgcggcgg 141480 gtattaacca catctaaaag ttcttttggt acaccgtggt ctgtcactag gctatccgga 141540 atgatgattt gtttgtaggt acgtttacga tcgtcaaacc aggatttgaa cgaggctgcg 141600 agtcttctat cctccatcga atccaaccat tctttgattt caactttggt gtccaggtct 141660 accggaatac gcatagcgtg atacggtggt tctggcacca ttccatattt tgtccctaat 141720 gtagcattgt acattaagtg gtaatggtag ttggattcag tctggtatga ttcttttgag 141780 ttgatatcca gtgttttaag ataaacacct tcaccagcac ggatagagcg ttcaacctct 141840 aactcaattt cagccacgcg tttcattact ggtaaaagct gaacatcttc accattcgca 141900 atctgcttag aaagacgttt aacagtggct ttgtactcat ccatgatttc gttagggatg 141960 ttagaagtac gtaatgcaac accttttaat tccagttctg ggtctgatcg tagagttcct 142020 tcttgcgatg tgataagtgc aaagtagtgt ttagcttttg tagttaagcc aaacgaatcg 142080 aatttaaatt cattcttcat cgagtactta aacaacttct catctgatac acctaattgc 142140 ttagacatcg aagccatcaa atgggcgatg ttttgcacta ccaagtatac cattgtatct 142200 gcaacacgag atgcttctac accagtatct ttaccacagt accactttga ccaccattgc 142260 gctgaaccca ttgttgagtc agtatccgaa accacaccaa ccgcacgaat tacttctggc 142320 attcgggcta tagtaggtgg cacgttttta gttgtcaaaa tagaacggat tagtaaagca 142380 tatgaaccaa tagtgttttg tagatggttc acggtagtca ttagtttacg ataatcgtct 142440 gggcgattat ctcgggcatc ttttaggtta ctgccaacac caactaaatc cgggcgcaat 142500 tgtgagacaa ggatacccat atcaccatcc atgcccttcg ccacacgttt aagctcttca 142560 tcactaattt cagattcttc aactggtgta atgattttct gaatgaacgt tcgcataaac 142620 tcatcgttgt atttagcaag gtggtacaaa tcacccatgt aaacaaacgc tgcacgttca 142680 tgaggtttag ctttagacaa tatctttttg attcgtctat cggctgctgg atttttgtag 142740 tagtcgcgtg tagagtgctg aataacttcg aaggtttctt caactgtcgg aatgtgtaga 142800 ttgtattcgc taatacagcg cttaaacaat ttccagtcag ttaaagtaca aatgcttaag 142860 aagtgattga ctacaatacc aggtgcccaa taatggcgac gtccacctaa taaacgttcg 142920 ttagcagcat taccgtaaga ggttgcggta cggcaagttg acgttagagc cgaatgtgaa 142980 gacatgttaa acaagatagt aaatggcgaa gagaagccac cagaacctgc gttgttcaaa 143040 gtcttcttag agttttgttc gttctttttg ttgatggcta gaacggtatt cttagcagct 143100 tgagcagcga acatttcttg cttgatacgt gcgcgctcgt taacgttgtg ctcaaagaag 143160 ctagctagtt ttgatttctt catcgactct ggcatgtaga ataccatcga tggtgcaaca 143220 atcaaatctt tctcttgggt agtcttaata actttatcca tcgggataag tttcttagtt 143280 cggtctttag tggttgggtc ttgcactaaa aactcaccga ctgggaaatc ttgtttaaac 143340 atcccatctt caccgaactc tttctgcatc catgcttcta cttcttcatg agatgcgtct 143400 gtcatcatct ggatatagtg tattacttgt tcttcgtaac cttggatgat atcaatctca 143460 cgaacgtatt ctgatttttg taaacggaaa ggtgattggt acacaccttc ttctgtgaaa 143520 gctttaattt gaccaatagg atcatcgctt tccgttgttg tcaataaagt atcggtcatc 143580 gtacaacttt ccaattaatt cctgtcacac gatcgccagt taccgtaaaa aaagaattgt 143640 ccctaggact acaactgtag tcctaggtct atcgagaatg gctttaaacc aaagctggta 143700 taaagaccga gtgcagcctc attattcact tcagtagtga cggataaatt agtacaaccc 143760 aatcgctttg cttcactcat tatggattgt atcaattgtt taccgtatcc acgtcgacga 143820 tactctgaat ccacacaaac cagacgtatg ccaagtacct cctcccattg ttgggttaaa 143880 gagaaaccac aaagataccc attctctaag atcaggtgta atgcacaatc acctgagtcg 143940 atgtcttttc tcagatcgtt ttgcatctct tctgttgttc tctctaattc catgctccac 144000 gagtcccaca caaaccctgt cttcttattg tgttcgtaag agttaaggct tagttgcttt 144060 actaactcac ccaatcgatt gatgtgatta ttcaatatcg gatcatcgtt gttgtagcaa 144120 atgtgtatca tgattgttac tccaatttcc tcttctcata ccaattggaa taagggttta 144180 ttttcttgat cgtttttttt tacggcggtg gtattataat atgcacaaaa ctgtcaggct 144240 ccggaaggag ggggaaaggg gctttctgta ataccctata atacgctata atttaccttt 144300 ggggaaaagc ggtataagag gttaggagag tacaagtaag aagactaaag gtaaaggatc 144360 gaaataagaa gatagaaaag gatcgatcga tccaaaaacc ttttttttat ttttttgatc 144420 aaaatttaca gagtaagatt ttgctatgtg aaaacgtata tagagggata tacaacatgg 144480 ctatgaaaat cttagactgg gaacaaagtc gagactatac cgatgaagaa tggagcaaag 144540 tcattcaatg ttggcacacc cttcactccc atctaccaga gatgaaaaga ctctgttata 144600 aactcgcagt cgataatttc gaattaccag atgaagacga attccaagta ctgaccgtag 144660 acactaaaga agaaagagaa gattctttag cttacgtgac agatgatggt attagcttca 144720 ctcacgattc aaaacgaatt gaaccgttca cactacacaa aaccgtacaa cacccccatg 144780 aaaggaatat caaaacccgt tatcacttct attgtgatgt agcacaaata ctaatggtaa 144840 tgtgtgagaa ggttgttcca ggtgtgttgg gcgactttga agaagacgaa ttatatcctg 144900 agctattagc tttgggtgag caattaatta gtgcggttaa tgaaccatcg gactacaaca 144960 tcgtaaaagg agaggaataa tggaaaatgt aatggagaag tataatttca cattccattt 145020 ttattcaaat cgttttttaa ctgaaggatt aaaagggaac gaggactttt caaaaatcga 145080 agagtcttac gatggcgtgg tcattgatag taaattacac cttatcaaaa ccagacaaat 145140 ggaagggcgt gtctggttca taaatggtga ggaggaagac ttcaagttaa aaatcgtcga 145200 ctcactcatc atggtaaatc gattacgtac ttgggaaaag ttacgtatta tggtcatcgg 145260 tgatattaat acattcgtaa aactcgcccc gtatttcaac actatcacag tacttggcgg 145320 attaagtcag gctgaaatag ataagtacac tgacttcatt gcaaaacaca caagagagaa 145380 tgatgaacaa ctgcaagaac caagctccac ccgtgttcgt gtaaggcaaa ataatcagta 145440 ctctactgtg ttcaatatga tgataccaga accttggata attgaccacg tctacgcaat 145500 ggattggact tttggttttg tacctgatac taccacaacg atttgttccg gtagcctatt 145560 attgaaccca aggtatggga attacacatt aggtagtgtg atggaaacat caaagccgtc 145620 gactaccttt aatagcgaac ttggtaaaaa atacgccttg gaaaaactat tgtctcgtac 145680 actagagaac gtcggaagta tctttgctta cacagaacac acacaatcaa agataccacc 145740 tttgtacgat atgcgcccat accaccttcg ggtaaaaaaa taaaaaaaga aagtaccctc 145800 gtaacgaggg tactctttta ctttttaacc acgtccatgt ctattacgtc ggcgagtttc 145860 actactaaac gtgcaatact cacgacgctg actgatagag ggatgacggc ggtcttcgaa 145920 accttctgtt agaaagccaa accgattact tctgctcctc ccagttacag agcttacaat 145980 gtcttcgaca ctatcgaggt gtgtattggt gttgtaacgt cgcagctcac cgtcttgtaa 146040 gtaatagata cattctagac cacctgcgat catctcatta attagagcaa atgtctctgc 146100 tggttcatca aaggtcacaa tggcacctgt cgcacccgct agactacaac gctcattaac 146160 ttctaccacc acatgaccag gtacattgat tagagtatct gtgaaattta agaatatggg 146220 cttttcattt tcttccaatt ccaactctaa tgctaacacc gcttgtggct cttcttgctt 146280 aatctcttct acttccacta cttctacctt gttttcagcc atgacaccca catccttaac 146340 ataatccaaa acaacagtcc aaccgttcaa ctccgataaa atataatttt gtagagcttc 146400 tttgagctgt gttaacttat ccacatcgaa tacttcggtt acaattagtt tgatgtacaa 146460 ttgtttatta acacatcgac cgaataattc aatttcacca atttccagag tgtcgtaaaa 146520 caaactgtat gttttacggg cacttaacat atccctagtt atgtacttca ccccaccaaa 146580 gagaaaccat agttgttttt gggtatattc actacgtttt ccaagctcta atttgtaaac 146640 gaaatccgtt ttaataggta cgatacatgg gtggagtagt ttaaagaact cgtccaagtt 146700 tgcacctgta tcggctgaat aagatatgtt gtccatgtcc atgactatcg aggtattgtg 146760 aaccacccct tccttatctt tgataccaaa tacatcaaca gtcttaaacg cctctctgta 146820 gatgttcaat atcgcccgtt tattcccacg tgctatacgc tgtaatgccg cttcttcgta 146880 ctggtaacgt ctgaataaac cagatagtag tctgattaca tttccctcat cgccgtgtaa 146940 cacaatacca gttaattttt cgctacactt actatacacg atcgaacaag agaagtccaa 147000 tgccacgacc aagacttctt catcattcag ggatataaaa ttagcgctga agttacccac 147060 atcatcaaca aggttatctg ttgtgtattc ataaggttca gataatacga ttggaatctt 147120 tctgttaatg cgtttacctt caacatagtc tttggtcact acgatgttta gatcttctag 147180 tactttcatt ataaatttcc tcttttctaa ttaaaaataa aaagtcagtt acagggacca 147240 atccctgtaa cctatatcac ttactgttta agatatcata aaccagctct tgactaaaac 147300 ctttgatcag cttaaccgtc tcgtcggttg ataaatccac acctgccagt atacaactat 147360 ctgaaagact accacgtagt tgcgactgtc catccagtgt atatacctcg ctgaggtact 147420 ttggtagaaa ctccatacgc ttctcattta taaccacagg aaccgcccac tcattatcat 147480 gggttaagat gtgcttcgat agaaatacaa aactccctac attgcgtttt agtgagataa 147540 cgactaaagc aaactcaggt acttccaccg caggtaaaaa gcgttcttcg cttggtagaa 147600 aatatttgat ggcacctgct cgaccatcta gaaattgttt tttatccacg accagtacat 147660 tgcccccatg agtgacctgc ttccatacat ttaccttctt gcgcatcgag gtacatactc 147720 gcaccgaata gtgatacgat tagtcccgct aagccaagac gtttgatagt gttgcgttgg 147780 aatacattca gtgatttaaa catttaaaat ttcctctcgt tagaatttat ttaatagctg 147840 cttcaacttt ggcgataagg ttagcacctt tgcgattgat tttgaattga acaaattgtg 147900 cgtctttttg tttcaacgcg taacctttct tagccaatac attcaagata cgaccaactg 147960 ccccatacga ccacttacct ttcaaaccca actcttgtcc agtactgtgg aagtaagcgt 148020 gagattcgcc gatgtaaagc caagtcccct tttggttatt taggatagtt agtgcaacgt 148080 atgcaggtaa tgttaaacca gatagtttaa tagcgatgat aaatttaaca agattttgca 148140 ttttaaaatt cctcggatgt tatcaaatta taagttgttt ttacagtgcg ttagaagctt 148200 tgccagcttc gtagatttca gagacggtct tgattgatag tttatgctta actgccaact 148260 tgacgatttc tttgtagtca ggagtatcag tatcaaaagt agaacgaata cataaccact 148320 catcctcaag acttagtgat agtacgattt ttgcatcatt aattcgatcg gctcttgtca 148380 gaagctcatc gtaatgtccg ttatcatcaa aggtcgaatc ggtgactaag acgttgtgat 148440 aatcgattgc acccttagct tcgtacttac cccagtgacc tttgtcgaca aagtcaatga 148500 gtgaatatgg cttggtcgag gcattgacga tatatagctt agggagttta tcacctggta 148560 acttcatgat ggccacaagt aaatttgtgt acatcacatc tttagttgaa agtagaaccg 148620 ctggtgagat gacatttgaa tcatcattac ccttgtggac aacggcaatg atttgtccag 148680 caactaagtc ttggtagata acctcattcg gtaatagcat ttaaaaactc ctctgtataa 148740 ttgaattgaa tgcagcatac accaagataa tatatacctg aaaaaaattt tattgagagt 148800 tagcaaaaaa taataaagtg agaggccgaa gcctctcaac actagagcaa tacttaaacc 148860 agtaagcaat gggtctggct aacggtttgt ctaggatact ttattaacat tgccttaaat 148920 agcgcactaa gataatgtgg gtgtgtgggg ttaccatacc attctgtagt ggtgatagta 148980 atcccacgtt cacgctccag tttttctttc tgtgagttca taacgccctt tgaaaccata 149040 gttattgaga atcttagtca agtcactgta ttccttggtc gatagcgaag ttaacttcaa 149100 agtgtaatct tcagtatcgt gacgtgtaaa ctcctctacc cagttgtcag caatggcaac 149160 acgtgtattg tcagccaaag attcgagaat ggtatagttt aataactccg cactctttgg 149220 agtgtcttct ggtagatagg ataagttaga tgcatgaatc ccatccacat cactgtagtt 149280 tttagcaatc tcgtaacctg tgcgagtcgc taagaccttg tactttgcat cggaagggat 149340 acgccctttg attgacagca caaggctaat tgtctcatgt aagacgagtg tgttcatatc 149400 agcactcata actccacctc tattctgtgt cggcatttac catacacttc accagtccat 149460 ttgaaatcct ctaaagaaat ctcaaactga gtatcaactt caactttctc gaagttgtac 149520 cactcttgta tagtgttgat tcgtcgacta attaattcga attttgacgc gtcaacgtta 149580 gctaagtatt ccgccaacat ttgactccac tgatctaaat caaggaactt accttcagtt 149640 ttaagtatac tcgaggtaag gatataatcg taattagcta caccttcgca atcagtatca 149700 cattccatcc ccaataacag atctgaaccg atatcctgaa ttttatcacg aagtcgtttt 149760 agcacagcct ctccatctgt acattcttct gtttcaccta ctggaacacc aaaaagatgt 149820 tccatcacca agtattcgat cagtaggata agttcacgct tttctttctt ttcgatagtg 149880 atgtgggtta ggcaaaagtt gacaaatgac aaataggcgt tgtggctcca caagttaggt 149940 aatttgacta ctgcaaacat tcccacacct ctaatcaagt aatctgtaat aaacgattta 150000 ctagttttga aacctgtctt tcgacagtat cgtaatcgtc gtttgtaatt tcaaggactt 150060 gtctatcctt ctttagaaaa agactgactg tccctgtttc tggataggaa cgcgtgctcg 150120 ttaaacggta agtgtaaata aaccactggc ttctatcttg taatccagca attatgatat 150180 ctaacaactg agctgcgttt tctctcatag tatcaataac tgaatcggta actatacgtt 150240 cgtagttgtc gacagcagcg gcgagtgtta acttatatgg ttcaatccac acatcgctat 150300 caacttccct tacattgtcg gttagagtac cgcagactgc ttcgatgatg ttatttacat 150360 cgtctattgc tgcctcgatt atggcttggt cctttaagaa tttgttactc ttagatgacg 150420 ttatactgaa ttctctattc cgcattttaa gattcctcga ataaaataaa ttgaagacac 150480 gtgctttcat tagatagaag gcacgtgtat attttaattg aaaattagga tagggttacc 150540 taattgatca ccgctggtga attcgaaatt acaaatgacg atatccatca aatcatcttc 150600 gatgttacac tccttagcat aactctcagc taaagacatc attatcatat cgtactggtc 150660 accgccgatg tcgaagatgc tatcaaataa ctcttctaga ctaccataaa ttgaacagta 150720 atcttcccat tcaacacatg tactggttcc cggtagcagt ggaatgaaat acacaccgcc 150780 atcatcctca cactcctcta tacagttcga tataaaggaa attcttagat tctcagcctg 150840 agtagtacca gcatagtgtt taatcaatat aacacaaaac catacaaaga ccagagcatc 150900 gccaacaaca tcttcgacgt catcaccgat tatttcttta gcagcacgta ctaagatgtc 150960 tttcagttca tcgtaagttt cttcgtcatt ctcaatcaga tgcctaacga tgtgcctagt 151020 ctttatatac tgtttcattc tttcttagcc ttattaacaa ttacaactac aagtcttgac 151080 aaagcttcga ttacttcttc ttttggtcga actggttcga ttactgagaa ttcaacagat 151140 aatgtttcat tatctctgtc gggataaatc cccacagtta tcttcttaat ctcgcagccg 151200 agaagaatgt ccggtataat ctcaagcata tcaagagcaa gtaacctaga atcgtcaggt 151260 aacttattga tacttaagag aacatcggac aaatcgttat tatttttaat agaacgatag 151320 acgacttctt tcaaagcctc tatagcaagc tccgccaatt ctataatgta ctcgtttagg 151380 tcatctgtta gaccaggtaa tgaaggatac ttattccaaa gattattgat tgttagtctt 151440 ctttttcgaa gtttctcaga aactcctctt ctagttcgtc ttgacataca cacctctcta 151500 ttataaagaa acgtccgcta gtatccattg ttagaaaagt acccatgaga tagtaatctt 151560 cgagtaactc ataagcaact cgtactatct cacgaatatt actctgcata aaaatgcgag 151620 tatcggcaca atctggcaac gcatcactga catcactttc gtcatagtta ggtctatgtt 151680 tgcaaaatac gacccagttg actaagtcac aaacatcata gtcatttacc cctcttaacc 151740 taaatatcct ttttggaatc agaagtttca tacactacac cgaatggaat gtcaccatcg 151800 tttgaattgg taaagtctaa atcgatcttc gaaatttctt catcgacaga ttccctgtaa 151860 tgtgaagcca ttcttttacc aacgtcccca tacaacatag agaaaccagg atcatcatat 151920 accaaacggg atgaagttaa accacgccca ttgctttgag gttgaatgct aacatcacca 151980 ctgggtaatg acataatgaa cccctcagga tagtcatctc taagggtatc tattaaacca 152040 ctgcattcgt ttagtatacc tttcggtata tcttcccgat cattgtggta gattacttga 152100 cctagcttat aatgcatagc tggtcctctt ttcccctcaa caaactggat gtggtctgtg 152160 atgggtttta agttattagg tctaactctg gtggtagaca taattcctct cctcgttgca 152220 atcttttcag agcaatgaat tcatcggtgg gtataacacc aatgtattta tctgaaagta 152280 ccacatcgtt gtatcgacca actaaacctt cgtgcttcaa tagagaaact acctctctga 152340 cttttgtctc agcaacaata gcaaagggta ttttgatacc atgtaccgtg tattgaaatg 152400 gtttggtttg acgattgtaa taaatgtggt tgataaacga accatacatc tgtaacttta 152460 gcatgttttc gtcagggtat ttgaattccg taagagggtc gcgtttaaca catggccaac 152520 cctctacaga aggaatcaag tgcaagtcat cgtaatcatt actgatttta ttcattacac 152580 ttattaggac tctgtgaatg tcgattctac aggtagcagt gacaatagtc cttctcttcg 152640 attgattcag catctttaat actacacgtc cctaaatcaa aaacttgacg gaatactatt 152700 tcttccaagg tttcagatga tttgaaaatg tagaagaaac aatccttttt gtaaatttca 152760 acgaccgtgg acggggtgat acccatcgtc tcataaatca tacccatggc tacttctata 152820 gcctcgaagt attcttcgaa tgtgaaagct agaagatcgt ctagactatc ttcttcatac 152880 ttttcattgt tatcttggtt gattgaatat gctaactcca ccaattgatg cttttcaaag 152940 tatgttagta gcgggtgctc tttaggggtt ataaaaccca tgagtgttga ttttaaatgg 153000 tgcgtaaaca tcgaaatgct tatatctaga aaatcactat cgtctagata ttttgcaaac 153060 ctcaaatgtg ccttagtcaa atcgaccaat aaccccgctt gtacttttcc aattaacttg 153120 aaccccggtg cacatcttgg atctttattg aggtaaggga tagtcaagta accatccttg 153180 taacgcattt caaaattgta atcgcgcttt ttctcgtgct cttccatggt atcgaaaaaa 153240 ccattgatta tgtaatcttc gatatcacga acccatttat cttttgggtt aacaccaaca 153300 gattcccata gagccgacac actagtcact tcttcataga tgtcgaaata tttttcaata 153360 gcactgcgca ttaaagtatc aaagattctt tttgcaggta gctcagcgcg ttcttcggga 153420 atcattcgaa taacttcgat taacccctcg ttaaaatcaa ttaccgccat tttttattat 153480 ccctagtatt tcaccgtcgt gataggtgaa gtgtacttgt tcattagaac acatcaccaa 153540 ctcgccaatc ttgaaccata aatcggagcc aaacatttcc tcgccagctt ctaagtcata 153600 tttgtttaga cagtaggccg cctcataccc gagaccaggg actattagtt cggctataga 153660 agcaaccaat tttatacgtg ctgaaataga agctctgtcc tctataacat ctataaaaaa 153720 ttgatcgctg atatagtagg tgagaatgat accaccagtt tccatataga caacctcgtt 153780 taatatttcc tcttcagact tataacatat atttgaaaag tcttagggtg tatagtctca 153840 taggaaactc tctggcgtga ttttttgcag ttggtatggg gtactattta taaaggagaa 153900 aaaatcgtga atattatcac acaggctctc cgacatgtaa ctggtgtaat cgaccgccga 153960 cttttgaccg atgcattcct cgatgaggat gaacgcgaca tgagaggtac acagttacta 154020 gagcagtcga tttatgaaaa ggtcattaag caatatgtcg tacctaattt atccacaatg 154080 ggtggtatcg aattagaaat cgaccttagc ggtattgatt acgtcagtat cgatagatgg 154140 acacgaagtt acgccatccc agtagaacgt cggatgggta aaaatattgt ggcggcacat 154200 tatgcaggtc gttctttgca tggtggatca acggcaatag taccaaacta ttacgaccat 154260 tatggacgta agactggttt actccaccaa ggtgctcgta tgagtgccaa ccatcaaccc 154320 atctatcaaa cacaaacagc cgatgtcact atcgttgctc caaacgtagt tgaggttaga 154380 gacttcaata ctgttgcaac aacttttgca ctagtggtta ctcttgagtt atcagaccaa 154440 cttgaagaga ttcgacaacc ttactggtca gaattcaact tgttggttga gcaggctgtt 154500 cgtcgtttta tttggactac acttcgagta gaactaaacg tcagtaaatt agaggctggt 154560 cgtgaattag atcaatataa tgccgccttg gaagaatgtg ccgatggtaa agtagcttac 154620 gaagaagaat tgaaaaagtg gccaaagtat ttgattctta atgatcgtcg ctcgcagcaa 154680 gcagtctacc gacatgctgg caagtaccac aactaaaaaa taaaccctct ctatcgtttg 154740 atagagagga gcttttattt aatgcatttt gtggaatgct gaacccgaag atgaatagtg 154800 ctcaacaaga taagcatgta accatccgct taacaccatg taattacata acccaagttc 154860 agcattgtta aagtgattag ttatgtaagc tctcatgaca cctttggtga acaatgggtc 154920 atggtggttc tcaagcatat ttaaataatg ttgaacgtat ggttcagtta catcaacttc 154980 gaaagtggca tactctgaga caggagagta atattctcgt gaaacgaatc tatagtaaag 155040 atgacctatg ttgtttaggc cactgaggat ttcttccgtg atgttttttt cgatgttgaa 155100 tctttgctgt gattcttctc ttttatttcc caccattttt cacttatcac ctcgttaagt 155160 ttggaaagcg cctgctcgta ttcaatacca gctagttctt ctggtacttt gatttctaat 155220 cttccacctg agtgaaaggc atggctctta agtctttgat taggatgctt tgaaaaacat 155280 gcatgtctca gcgcacgatt aaaatcattt ttggtgctaa ttgtatggat ggatatagtg 155340 tcccgccata cctctttttc aaggaattga tcgaatgtca caataaccct cctacaataa 155400 atgataacag ttccccatag taaaatccta acatcgttaa aaagtacata tagtatgtag 155460 agatgccatt gtacagcaaa aaaaatattt gcttattata tggacagaat ttattcgcct 155520 gattagaaag atgaactgta gcagtttcct cctttcagct ttttggttaa tcgttagttc 155580 cgtgtacaga gttagcttga tagcgagcaa tactgtgact acgttctgac atcttcatca 155640 ggcgaatata cctaatcttc tgaagctaac gacggttgtt ccggcatgat attcctcttc 155700 cgagctaaag aagcaaaatc ctcaagtggt gagatgtagg gttcgaccct cttgaggtga 155760 cgttgaaacg cgtccaacgt ccaacagggg tgggtaagat gacgcgccgc atccaccccc 155820 gtaactattt tgaaaggtag ataaatccct taaccaattt acagattcgc tatgtgttga 155880 tgtctgcctt tcaattcttt atttgcatgt tagtgcaaac aggtccttcc tcagctcgca 155940 actaagttat ggacctgacc ctattcgagg agtgtgctct cctgtgtcgt ccggttgtat 156000 atcccatgtt tcctgtatcg ccaccgcaca ctcctcgagc caactttggc cgccagctaa 156060 agtgaaccac tgctttgagt ttattttaaa cttctcccct cttaggattc taagaggggt 156120 ttttgttatt tttttcttct cggcaaaaaa agaaggtagg ggtcgaaacc cctacaattt 156180 agatttttgc tttgatagga acgggttcaa gtacaacact tccatcatct tgtaccaaca 156240 cacgattacc ttcgatcatc ccataacctt ccacttcgtt ctcgtagtac aaaccaaata 156300 aatgtatttg taaacccgaa gcgtaaaaca tagtgttgcc cataatgctt ttgatgtaat 156360 cgtcactatt ggcatcgaga gtcgctttag tgattactgt gtacgggtaa aaacgttcac 156420 gttcatgatc atctactcga actggtccaa gtaatataac cggagagatg ttctttaatc 156480 caagtgccag tttcatcaat gggcgacctt ggttatgtag aacatactct ttgatgcttg 156540 aaccattgac ttcaacagtt gttgtgtcga tggtggcact ttcaatttgt cgtttactta 156600 gcaacataat tagtcctcct ccgacttaat ttcatgtacg actgctgatg ttaaattatt 156660 taaacagttt gtgtaggtag actcagtgta cttgacccga accactgtac ccacaacact 156720 ctccggagaa gagccctcgt acttcgcacg aattggtcta acaccttgtg gtaattcgac 156780 atggactact agagtctttc catctacagc aactaccaaa ccattgcaac tacgacttgg 156840 taatatgtgg tattcattat caccatcaac cacatacaac ccatcgtact ctcgatcttt 156900 tgaacgcgta gtatttagat ggatgacatt accagccttc actgttgtcg ctgacacact 156960 acggcaagca aaaggcaaat caccatctgg caaatcccca aaggtaaata ctgtcaaggt 157020 atctaaccaa gaaccgcctt cggagttatt gctgatttgg taagttaacc aacgtgatat 157080 cgccactgga ggcatatcgc gatatataac gattctacct tcgtaccctg cctttgttag 157140 agctgtggcg attggctcgt ctaagaagat acgatggtag ttgtcaagga cagcagcccc 157200 atcttcagaa agatagacgt ggcagaatat ccctcttggt ttagagaaga cacgaacatc 157260 cttttccata gggtctgata gtgatgagag aaactcattc cacatcactt ttgtttttgg 157320 tttttcgata gaagcaatca ttataaattt cctcttaaat agcatttcca gaattgcatt 157380 tcttcaatat gataatatat atctgttaat tattagagtt aatatgagct gagtattaag 157440 ggaatcatta tgtttgaaga gtacttgaac ttacttcaac ctagaaagct ttcaaccgag 157500 aagcttaagg aaggtgagtt aaaaatgaag caagctctag cagaagctgc tcccaacttt 157560 acagttgata aaaaactctg caataggata ctgtctttct atcaacgaat taaaagttcc 157620 gagtggaaca ttaactggtt tggtggatgc taccttggaa ctgaacttat ccgctttaca 157680 caacaagaca gggacagatg gtttgatgaa gttcttgaag tagacgaaga ttacttagag 157740 aatatcttag agagaacagg tattcgtagt gactggaatg tttcatcaga tgcttttggt 157800 atcattaacg ggtacgtgtt gcataaagcc tatctagcct caccgggctt taaagacaaa 157860 cttatctacg acgcaatgcg tgcattgtta tctgtgtggc agtttcgcta ttatagctcg 157920 ctttatagca ttcgttttaa aagaaatctg gttgacagac ctgctgccga agcagcatat 157980 gctgccctca ccatgaagtt cactattaag caacttggta actggggtgc tgctatagag 158040 taccgtgctg aacgtttctt agataagtct tcaccccatg ctaacacgta caaaacatac 158100 gacgatatca acgatgttgt ttacatcgcc acggatctat ctacacgatg taatcgaaca 158160 ttctacgatt actacaatag tctggataag gtgaggaaga ataactcacg tattggagtc 158220 tacgaggaga tagcaacggt tgagggtgag caaatactca aagatagaac gagtatacaa 158280 accctagcta ttgagtattt gttaagttct tcaacttcaa catcctcgtt cgtaactaac 158340 caatatcttg atcttgtcaa tgaactcatc actacgtcgt caccaacggc ggttaaagat 158400 actctcattg ccatttctaa tttaccactg ggtaaagaaa gagatgagat agaagatgtg 158460 atgagacgag tcttgatata tacgtttaac tacgttatgg aaaacagact caagttcaca 158520 caggtgtctt tgttattaac caaaatccgt gcaatcatca ccgcatctaa gaacaaagag 158580 gacgatgtgg tgtttatgcg tgaacgcaca gaaaaattca tcactaagca cacacacctt 158640 aaacatgaca ccacagtagc ctcatgtcgt accgcagtgc tcctgtactt cattgtgaag 158700 ggtttgtctg ccaacaaaca gtaaaggtat ctagtatgga agtaaagggc tacagaaccc 158760 cggaggagtg ctttgcggcc tacttcggtt tagactctgt tgaagaactg aaagaagtcg 158820 attgcatcaa tgctattgat gagaaaggtg agttggtcaa ggtcaacgaa gaagacctct 158880 ttgcaggaat acgaaccttg ggtatttggg ggtgggtgga tgacaatagt actatacact 158940 attggcgtgg cgaagacgtt gactcaccaa ctgtgataca tttcctagga catgaaatcg 159000 ggcacttgac cggagactgt cacgaagacg agtataaaga agagttgcgt gctgaagaat 159060 tcggcctcgt ggcttctaaa gcttttgagt tactgacaaa gattattcct gtctaagtcg 159120 ataaaaaaga aagatgttac ccacctatgg tgggtaacga ttcttttatt tttctccaat 159180 cccattcgtt aaacattcca aaaatgttcc gacagggcac caacccaaaa gagaccagta 159240 ttatagactc aataatttcc gatttggcgg attgggggag aagtacctct ttcgagggtg 159300 cgtcccagtc aatcaccatg tcgcccgtgt aaacaaacat gataaaccaa cctagatgca 159360 aagtatatat tagaggaata cccctgctaa tcattgactt accttcaaag tgacagtgct 159420 ctccatatta tagctacgcg cagttttaaa aagttgttcc ttttcaaaag cttgtgcaga 159480 taaggttaca gttgccccta accaacccac accaacagaa aaacttagtg ccacgaatac 159540 agcaacgcga acaaaaagct tacaatgttt tttagaaaag gataatgtgg caatccagtc 159600 catcagctca aataacatcc aaccgagtcc taggactata ccaccattaa cgaacacact 159660 tcccatcatc tgcctaacct ccttctaaag cgttcagctt taataagttc cttataatca 159720 cttagagtgt tagcagcccc tggtttaatg gaagtcttag taaccagatt tttcaatttg 159780 gtttctaatc gcatcttagt gacgatatca cgtgtagtcg acaaagtctc atagagaact 159840 tcaatttcgt ctagaatgcg aagttgttcc tcgttttcat taacgattct ttcttcttca 159900 tctagtgtga tatccccacc gaagtcagct ttaagacgtg cacgtttttg atcaacaccg 159960 taaaaacgtg tattcttagc aaggaagata aaccagaatg ccaataacca agccaccacc 160020 atatcgtcgt gcccagagtt gatgtggtca atacgttccc ttttgacaac aagagcaagt 160080 aactgatcaa tcaatatttc cgaacgtgca actttcttag cagtagctat agcactaccg 160140 aatacctcgc cgtataacgt tttacgttta ccaccatctg ttttgaaacc gatttcttta 160200 cgaaactcca tccagaaatc ttcagcgcga ccagacggtc cgcgtacgta cttcttgtat 160260 gttgggtcag acgtgtcttt aaactgagta atgttacagt aaagacgatg gtgtaaatct 160320 tttaccaccc cgcttagttt ctcaagaaga gcatcgacga taacaccgcc agtagacttc 160380 ctctcgatca ctaatactgt cttagggtat tttaataata actcacccaa ccagtcagcg 160440 taacgaataa tgttggtttc attaatctcc gaatcagcag aggtctccag agtttctgaa 160500 ttaaccatac ataggctaag agaatctcga ccaacaccct cagaagtatc taaaccaata 160560 acatgcattg tttctgacat tcttttttct acatcttctc ttggaatgta ccagttaaga 160620 atgtagcgat tggaaaatat ctccttccat aaaggtttga ccttatgctc ttttagagtc 160680 ttggcatcgg cctctgacag aggagaagac attcgaccag cggtccaacg accaccgtag 160740 tctcgtgcga tttgttcagg tgtgccggac gcatttcgaa tcatatcgaa taactcgtcg 160800 tcggtagtac ccaattgatt atgattaaat ttgatgtaga agatacgtcg tggaaccttt 160860 gcagctgagt ttttatcaat cagctccaga agttccttac gtgttggtaa gtcaatgaag 160920 cgttcatccc atttgatacc tgaagtcatc aggttgtaca tgtacgcacc ttctggtgaa 160980 tctaactcac ccggcgtagt tacaaagaag ttggcgtaag gtacaccttc tgcctcattt 161040 gccttacgcg ctgcaacacc cgaaccaaat gccgcaggaa gaatgatgtg gatgtatggt 161100 gtaaagggac cctcatccga accaagtctt cccgcagtta acccacgtcc ctgggagttg 161160 gcacttgccg ggttgttttg accgatggcg gtgatgagct ttgtgtttct agcaacgcta 161220 ccaaaagtct cttggttatc agggtctttt ggatctggaa cccatatacc tggaggaaga 161280 tggtcacgca tgtgctttaa cttctcaatg gtctcggcac gcagcttagg gtctttggta 161340 attaggattg aacgagcgtt ttctaatatc cttgttagat acaagaataa tccactgata 161400 ccgacagttt taccgtgctg gcgcagaaac tccagcgccg catcgatgtt cgagaagaaa 161460 caccaatata gtgcaaaagt accacggtta attttgaaag gtactgggtc accaccatcg 161520 ataggtactt tgatacattc gcggaatgcg taccatgggt ttgaacagaa ctcctttgcg 161580 attcgaagaa catactcttc gctaagagta tcgtcaaagg ggtccacacc gatcaatttt 161640 tgatcgtgta atgctagcgg tagataccag tttttttgaa cacccactct ccgtagaatc 161700 tcagccatct caataaaact tttattggtc gtagtgaaat ccggacgggc ttctgggtat 161760 agtctccaat cggtaggttt taagatcatt caaatactag gtggggttac ccccaccccc 161820 ctcaactgat gtcacggtgt acaatcatac cacaaatagc taattctaaa tcatccttag 161880 cttcacgacg aatccaacgc aattcgactg ttgaaccctg tgtgatttcc gatgggacgt 161940 caatagtctg ataccagttg gatactggtg cttcgtatgt cttagtccca atacgcactt 162000 ggaagtgcgt aggggttaaa ggaccacttt ccgcgattct atcgtaaagt ggataagttg 162060 tgtagtacaa cttatttaac cactcggtca aactattaca cccgcacgaa acatcgagcg 162120 tcgactgtga aacgttgttg tagtcgtaca ctgcaaaagt atcagtgccg aatgactcct 162180 caccatgaac atattcgagg atgaagttcg tcccacgaat agaaccttca cgaacaagtg 162240 taatgttgaa actttgtgcg tgttggtgtg gtttatagga agcattaacg gcattggcat 162300 ccacactgac gtttagcttt tgtttaaccc catacagtgt tgggtcaaaa gcatcaagtc 162360 cagtcgctgg tcgcacataa gcagtggcat cgtaaatatt accacgtcgt aaatcgtaga 162420 ggtagtagcg taaacgataa ccagctgttg cattgaccca ctcgggaaca acaaatagtt 162480 ttagcgagta tgcgccatcg actacttccg tgactgcaaa gtaatctttc acgattgttc 162540 cgccaaccaa atcttgtccg gtgtagattt catttttacc taagcggtat gtgaacaaca 162600 aatccaattc ttgccctgcg ttggtcgaca agtagaacgt gtcatgtgta ccagcattac 162660 gtaaaccaat tagactagct cttgcttcgt ccaatgggat ttcgacttta ccgtcattgt 162720 aaataacctc cacacttagc aagatatcat cgtatggaat gttgataggt aaacgaagga 162780 tgttcgaggt tggggtagtc aaccacggag atttaagacg gacgtctttc acaacacgtt 162840 gtggggcttc tgcttttgaa atatacgctg tcttaataag ctgcgcactt tcaactaccg 162900 agacaatacc agctgaatca tagacaacgt agaatacttc tagatggtcg ccatcaatcg 162960 gtttagttaa aacgccagtg agaggcacct tcaccaaatc atcgctttcc gaattcgtca 163020 gtggaatatc cgtacttacc aattccccac ctttctgata accagagatg atgtttttgt 163080 catcaccgat atcattggtt aagaatacac gaatgctttc cgcacccggg atgttgaaac 163140 cgaagcgtgg atcgaagcgt aatgtaggtg gtgattttgt ctcatcgaca tagatgcggg 163200 agaatttact gttatagtaa ttcaccgcac ccttcaccac gttaccaccg atatcattac 163260 cattgatgcc ccagatacga tgctcatact ggtagttggt gtaatcgacg gatgtaaaca 163320 cccgtctttg atcaacacca ttcatcaata catgatcacc cacgttagga acaaatcgtc 163380 cattttcgtg ccaaccataa atgtcatttt cgttgaagtc acgatgtggc gagtctcgat 163440 cgatcaacgg agccttaatt gaagacatta gtcattcctt atcgtcaagt aacgatttaa 163500 atctacacgc tttttataaa aacgcgaatt gattctttcc aacacagtgt aaagtaacgc 163560 acttacttcc actgtcccaa atccccagtg tgggtcaaca acaacgaacc aatcattcac 163620 acctaggtag gccgggtctg tgctaagtag atggtcgtat cgtccaacaa tctcatcgag 163680 ttgttttgtg gtaactttgt aatcgtcatc atcttcgaca attaccaaat caccattttt 163740 ccaatcagtg ataatcttgt taaacagagg actgtataga ggatagcgat actgtagcgg 163800 ctgctccata gttagaacag gacgaggata gtgtatcgta agaaaatcct ccactaattt 163860 atctctttct aaagcagcca gtctgcggtc atcgtaatga ccttctaaca aatcaccagc 163920 aggaatcgca accgaatcaa ccgagtaagg taacccgttt aactcactat caaccacagc 163980 tgcttcatcc tcacggaatt tcacagagtc ttgtgtgaag attgacccac cgacgacaat 164040 acgattgacc ttgtcatctt taatgtcata atggtcattt tcagaaagca accctccgac 164100 aacaaacccg gtcttgggtg ccactagttc cttagcgggt acgcgcgctc gcaccacaac 164160 cgtctggtct ttgcctggca ataagtgggt tttattcgtc accgttaccg atggccaatc 164220 aacaagatag tcgattccat aaactagagg tcgtttattt aaaaagactt ctagcgtcgc 164280 aaacttaaat ggacatggga ccaacgtgcc atcttgtagg ctatgtttca caccaacacg 164340 aatcaacccc tcagattcac tgatagtctc ttcataaacc aagtgacgct tatctgataa 164400 tgcaatactg cgatatcttt cagtatcata attccaaaca agctttaacc catcatcaat 164460 ctccactgtg tcgcggtcgt ctgtaacgtc gatgaactct tgtactggaa caccgtcttt 164520 taatcgttgt aagtagaaac gataagattg gtaacgtgaa acaagtaagt tatcagcccc 164580 ccaaactaca tcaagatcca caccaccaaa ccccgggatt ccctcgatga ttttagtgtt 164640 gttacgccga caaatataga taccttgttg atgcgtccac catccactta aatggccttc 164700 ttcatcatac tcgtaaatag tcgactgttc ttcaagtaaa ggcggcaatg tggcataact 164760 acgaccgtcg tcaccttgtt ctgtagccat aggggtattc gcagagtaga atagcgcagc 164820 attgtacccg tatgcatcag aagctagttt gtggtcaata cctctgaagt cacacgttct 164880 caaacggttt atctgagatt gctctagatt agctgcccgc cagaaatcca atgcgctatt 164940 taatccagtc atcacattga tgatctcttc atcatttaga cgatagagtt cgtggattct 165000 gtaatcgtta taaagcatag ttcgattaaa accagacttt ttaacaaaga acagaagttc 165060 taaattggat gacttaagaa cctcggtgta ctcttccacc tgcttacaag acatggcgaa 165120 gtcgccgtgc gttagctgcg tgaaactact tctgaagtgt ttgttgtaat agcgtccttc 165180 ctcaccattc caaacgtaga tgtcgatgtc atcgtggaaa tcaaaatctt ttgtcttagg 165240 aaaatgaaca agaaactttt tcatattgtc gagtgttgac ataaaacttc tcatgtcaga 165300 cactgggatt ctaacaacgc gcttaatact tttatcgata tagaactcta ccacgtcacc 165360 gatgttgaca ttagtggttt ttaagccttc gcgataaata ccatttacga aacatcttaa 165420 tgacggttct tggtatcgta gattgtggta ataatccgcc aattgtgaaa tttgataact 165480 atcctttggt ctctggatag tcacagtcaa cccattaccc acgccttctg ggctatcgtg 165540 tttgatataa tggtcataga cgcgtaagta gagttgcgcc acatgtacat ctaagtaacg 165600 gctatctttt ttgatggcta agactaaacc gtcactcatc aaacgacgca caaacactaa 165660 atctgaaggt tgacgtttac catcgatgtc gtaaacgaaa atcatagcac ctgtgcgatt 165720 aatgatttcg tttagtggaa cccaaccgtg gtgatagttt atgttcaact ggccacgttt 165780 agcgtggaga aaccccacgt tataaacagc gtagaaatcg gactctgttg gtagtccgat 165840 ggattcacca tgcacattta taaatgttct atcgagatat ttggaactaa cccgtgacaa 165900 tttaacattc aattgtccat cgataccagg tttagcccaa acattctctt cagcatgttt 165960 gattaaccaa gttcgcatca ttgctcctta gtgtactcca cacgacgttg gatgattgca 166020 ggaagttttt cacgaacttt actgtcttta taaagttgtg ccccaagagc agacttctta 166080 agaaaagagt tctctaggat agtgtagacc attgccagaa aagctggtgg gtgacgcaga 166140 ccaagctcaa tgacagattt aacctgaccg atgccgaata ctgtacgtga catcacgtta 166200 cctaacataa gtgcattgaa agagttcaat tgtaaattga tattggcgtt aaccacgaac 166260 ttacagaact cttcgactgt tctagggaag ttgacttcct ggtcagcaga aacaaatgag 166320 atagattcat cgttagtaat cacatgttta gtcaataaac gatgtaattg ggtttcctgc 166380 atccccggct ctacatggct gtggaacata ccaatgtagt atagaccaac acacgtctct 166440 agacgcattt tctcgctcca gtccatacgt tggtcatgtg caatattctg cccaatccac 166500 tccgcaaaat gcttaagtgc atcagaacaa gcatagagca actcatcttt atttttcaaa 166560 ttaatccagt ctagttctag ataggctaag gtatcaaaat acatagccgt gatttcgtta 166620 cggattttta tggagacttt gtctttacca actgtggtaa aaccacgagc atcgacataa 166680 atttctttac catcagatga cacaattggg aagtcgaaag gtgcgatgtt acttgcttct 166740 tctgtgatat agattagacg gggcgaacgt ttaaataaac ctttgcctga aattttagcc 166800 aattcaatct ctgaacgcaa ggtgttgatg agataaccat catccaattt taactcttct 166860 aatgttcttg acattttcat ttgcctcttt actttaaaaa attacgttca ttactatgag 166920 ccactgctta atggcgtttt agtaaataaa ggagctcttt atgtttacac cgcgtaacgg 166980 tgttccatat aaccaaaagc taggtatgca ggacaactct gttcagcgtg cagtagctgc 167040 ggctatcggg gacccgattc acaagccact gatttttaca ttcagtgcaa agggtgacac 167100 caacgaggct tatccagtcg caggtggtaa cctgaccaat aagttcggcg ctgagatgtt 167160 ggacccgcgt tcaaaatacg caacattcaa caccccattc gctcaattgt ttaactctct 167220 cggtaacgag atgatggtgc aacgtctgga aacaccagat ggtaaaacag catctgctcg 167280 tgcagaaatc gaagtcattg aaacgacggt tgatatctac gagaaagacg catccggtga 167340 cgttgtcatt ggtgccgatg gtaaccctaa gattgcttcg caacgtgaag gtcttaagat 167400 cattcatcgt atcgttccaa tcgatgatag caagggtgaa ttcggtcagg gtaaaaagta 167460 cgatggtaca attactggta cttctggtaa aacctctcgt atctacccac tgtacgacgt 167520 agttgcacct tactacggcg aagcagcaaa ccgtttcggt tggaccattg aagtgatgca 167580 tagcgaatca gccagcccgg ttgacgcaga tatgcaaaac tctgtaggta gtcgtatcta 167640 ccgcttcgaa gctttcgagc aattagaaga cggtgctaag ccagttaact ggcctatgtt 167700 gaacggcggt cgcgaattca aatttgcact taaagaaggt gcatactacg acgaactacg 167760 tctagatttg gattaccgcg agttactacc tggtgcttac cgtaacatga cacctgttat 167820 cggcatgttg ccagaagatg gtatcttcaa agatttccac ttctaccacg acaacttcgc 167880 tgaagtcgtt gctctgatgc aacagcatgg tgctgatggc gcaaatccga tgccagcaga 167940 cgcatacatg atcgatattt tcggtggtgt aaacgttcat ggccaaccat atgatgggat 168000 cgtagttaac ccttctgacg caacaaacgt agcgaattac actgcaaagt ctgttcacta 168060 catgaagggt ggtgctgacg gcaccatgac taatgaagtc tatgactctc ttgttcgtca 168120 agagatgact gtctttggtt ggggtaaagt caagtacgac aatgaactga aatacggtct 168180 gggtatcctg tacgactctg gctttagttt cgacactaaa gaaaaactgg ttaacttcat 168240 ccttaaccag aagggtacgt tccttgtatt gtctactcac ctgtggggta aacataacga 168300 tgagcaagaa gaagaagcgg caaaagtagc tgtggcggct atgttgtcta ttgcccctga 168360 gtctatcttc tacggtactg gtgcgggtgc acgtgcgatg ttggtgagcc aagcttacaa 168420 actgaacaac agcacttaca aaccacttgt cccgctgacc tacacattgg cgcgactact 168480 gtcaaactac gctggttcaa aagaccctcg ctttaaccct actaagggct ttagccgtgg 168540 tgagcataca atcattaccg aaggtactga tctgaatctt acctataaac cgatgagtac 168600 ttactcaacg gactgggact tgggtgttat tgcggcacgt aacttcgatt accaccgtta 168660 cttcttgcca gcggtttcaa ctgcttttgc tgatggccgt tcagttcttc gtaatggtct 168720 attcactttc gcaatgtctt gggttgaacg tgtttctaac caagtttggg cagagtgttc 168780 cggtgaaagc acattgagcg acagccaata cgcaaaactt gtggaagata agatcatcga 168840 taagattcaa ggtcgcttgg atactatcgc gactatccgc ccatacgtct acttcactga 168900 agaagatgtg cgtaatggta acacagctac agttgacctg tatgctgaag gtcagccgct 168960 taaaacacaa cataagacga cgatcaaagt atctcgtcct agcgaggagt gatgaagaat 169020 ggctggtgaa tctaaagctg catttatcga caagagtgtc ggttaccatc agaatggtgg 169080 tcttcaaact attatcgatg catcacaagg cggacagaat ggtccggcgc tgcaacctgg 169140 taagtacgtc cagaacgcag ctgacgtcat tcgtagctgg caggtgcgtg ttatcgattt 169200 cccacgctgg acctacttca tggagaaccc tgctgcatgg caacgtgcaa tcaaggcctt 169260 cgttgaaact cacaccatcc acactggtat tgagttcggt ctaagcgcag agtacctaga 169320 aacacaaatt ggtcactctg ataaaatcca atacgacgct ggccgtgttg tagaagcttc 169380 ttctaatatc aacatgacca cgccggataa gtacggtgca tacttccaac gtatgctttc 169440 aacctggttg aaactttcag ttggtgaccc tgcaacagga cgtccgtcta ttgcggctat 169500 caacaaagac gtgaaagacc acctacctga tatgtacagt atgtccctgc tgtattaccg 169560 taccgatgca tacaacaaag aagtgctgga cgccgtttac attgtgaaca tggctccacg 169620 ttctgatggc gcagctgctg gtttccgtga ccacactgct gcaccacagt tgaatgaaat 169680 gtccatcgac tggacaggcc ttcaaacgac tggttggggt attatgaaga tggcacagga 169740 cgacctagag cgttctaagc tattcggatt acgtcctgat cttcgtaaag cgtggattga 169800 cggcgcaaca cctgatgtta attctactac tggtggtgtt agcacagttg tagacgacat 169860 cgctaaaaac ctagttaaat aggtgaaaaa aagagagaga ggcctcggcc tctctttttt 169920 ttatttttta tctctgtctt gtggcgcgtt caatctcttt gtgatttact aagatgatat 169980 ggcgagccgt aaagatagtg aggtagtaca taaaagacac gagttgattt ttgtctaact 170040 cgtatacttc tttgtcaaca tctttctctg taaagatagc ttcttttaca tcaatatcat 170100 ttgctttaat gatactcaga gctaacttaa cataggcttt gatgacccgc aattcatcct 170160 cacccagata aaggttagaa agacaagagt ttgcaaattg ctcaacaacc tcgacattgc 170220 cgaccttttc aaaggtttct ttgaagcgct ctataccagc gatggtaaat aggtcaatgt 170280 ggtttctttt actgattaca gagtacacgc tagtatcgcc tttggtgacg atatcggcga 170340 caacatagtt atgcaatgac tcagaggtca ttgtagtaaa accaaccagt ttatcttttt 170400 cttcagacat aactaatccc aataaaaaaa taatggaggg cgaaccctcc attgatgaat 170460 ctacaaccaa cgattagtcg taaaggttac cgatacgtga acgtacgtca gacaacagac 170520 cttcttcagc atcgactgag caacgaagag agaatgagtt aacacgatct tctttgcttg 170580 catcttcagc tgtaggacgt gcataatcca gagcgtaggt ggcgaacggc gttttgaatt 170640 ctactgtggc attgtctaca ttcggatttg ccttcgtgta gtttgccaaa ggttcagctg 170700 cgaaacggtg gaagttgtta ccccattcct tttcgtgaga cgctaccttt tcaacagtct 170760 cacggtcaac accttctggt agggttgcaa agtactgttc actaagaccg tcttggtcga 170820 cgataatagc tttaccttct tcagcgcgga ttgcttctgc tacaagtttt gcatatacag 170880 catttgccat ggtgatgatt tcctttttac aataaattaa atgaatacga ttttgagata 170940 agaagaatgt gcatctctct cactatgata atatataccc gtattttttt aggctgttac 171000 ttccaataga tgcatctgtt caattgcatc atcgatgcgt ttacacacat cgctcgaatt 171060 gtattcgtta gcacgcacgt gaatcgcaaa gccacctgct tcagtgaaac gctcacaatt 171120 aacacgccag tcgtccacaa gaatattgtg tgggttcgca taattaatct tggcagcact 171180 ggtaggggta acaattatct tgtttgcacc tatcccccac tcgcgttcaa accataggat 171240 ttttgattct tttgctttta ggaaagatgg gtgcgcttca cccgcagctg tacagatcat 171300 ccaacgttca ccagagcgtt cacaatgttc gatgatgtca atgaactgct cgatctttgg 171360 tagcgtgtta aagaagttag aatctttcgt aaaaacatca actaagaaat tatgctgctc 171420 tgcatcattc atagctgaga aatctgacca tgggatgtat tttgccaatc ctgctttaaa 171480 attagcagct aaaccatctg agtctaatag tatcattttg ttagttcctt taagtttaat 171540 aatgaaagta ggttttctta catataaaat cctgttgtgt aaaataaagc tgtaccctga 171600 catttgtcag ggtacgctat ttattaatca caaatcaaag taacacgggt cctatctcga 171660 cgaaagggca acacttttgc ctctttcacc tcccccaccg cagatactat ttcatcgtgg 171720 atgaaattaa ggtcggcttc attaacgcga ttagcgattg atttagccac ccgtcgttga 171780 ttagggtatc ttctctcaac tagagaaacg atggtatctt tggacaagac cgttttggcg 171840 gactctttaa agataaaccc tacctcctca tcactcagtg aatacagtga atctggaacc 171900 tctacatttg ttgttacact cataaatcga tggttctctt atcttaatgg tagtcttgca 171960 caacgccacc ctagttaagt aaaatgaaca tcgaatttac cttctgatta tcttagaaaa 172020 tcgcctttgg ccacaggagt gatttcgatt gtcttgccga taacgttacc atcttcccaa 172080 tcaacttgaa ctgttgcacg ataacattca cccggattac cttcgtaacc ctccttaaga 172140 aaggcgtagt cattcaaact gatgtgtgcg tcaaaaatgg tttttgtccc atcgcgacta 172200 ttcaacacat ccttaatgac aattttaccc caaacccaac tttggtaatc tgactgtgtt 172260 ggatcgtaat taactatcca acgttcgttt aaattagcag aattaggtag gggtttcttt 172320 gttggtttta acgagatggc tggctcaaag ccataaatcg tcaaagtgat ttcttcgtca 172380 ctgatgatac gctcaatctg cgtgtctatc ataccgatag tagcatccaa tacattattc 172440 gatgtgcaga ttctagcaat tgtgttgtct tcaccaggct ttacaaaatt tggaatcttt 172500 ggaaagaact ttctgattgt ggaagatggc gatacgtgga atagacgctc gcgctccttg 172560 atagtgaagg agttaacgta ctcgttcttt tgtaacttaa accaatagtc tataaaacga 172620 cgtttcgcct caagactttg ctttcttaat tctgcctcag tgatcaacat acaggttacc 172680 agtcagttga aaatacacct ttagatttaa cttgcacgcc cggagtcgta ccgcagattt 172740 ctttgatgcg acgcgatacg taagattctg ttgcgagctt acgaccagat gtcacttcaa 172800 tgttttcaca ttgtagaaca cgctcagcca agttagaggt gagtccaata gaaacagatt 172860 cacgtgccat ggtacgttca ttcgtaatct catagcccgc ttctgcataa aatttgtttg 172920 cctttgaaac acccggttca ataacccagt cgaaagtgat gacttcatca atcatcaaga 172980 atttctggcc accgacccat ttttcacgta cccaacagcg gatagagaag caaacatttt 173040 gatgtgggtt gtcaagcgca gctttcaagt actcaccgcg cattttatcc ggtttaaccc 173100 atccccagat ttcccaaaca ggcagaccat tgcaagtttg tttagttgga acgaattcca 173160 tctcacggat atgacaagca atgcggtcgg tgtcgatatc ctcgttgcga agtaggaatt 173220 gctcttcggt catccaacct tcccatacag gatggttgtc ctcgccgtaa aggttcccac 173280 catgcatctt acgtttgaat tttgttgagt cgtcaaacgc tggtagagat gcttcgtatt 173340 cgtaaaagtg gccttctgag ttaaagatat tcagagcccc taagcaaacc caatagtaat 173400 caccatcacg ttttactttt gaggggtctg taataccatc caaagccaca catcgatagc 173460 ttaaattaga catatagttt caataccctt gttactctac ttcatgaaga gactttctaa 173520 aggctcctcc cgaacaggtt cattcaacat agcggcacgt aaaccacgct ttaactcact 173580 gttggcaacc aaagacaagt tagaagaacg gttcaatgca ccattacgta aaggaacagt 173640 ggtggctggt ttcttacaac ctgccaaaga tttatcagca tgtcgtgcga atcgtttgat 173700 atcacctggg tcacgacaaa tctgactagc taaaacatcc aacgtgattt gcgaattgtg 173760 gatctttagc ccgttgaagt acttggtgcg ggaaagaagc tcagctaagt ctacacgact 173820 catccaccaa ggtgaatggc cataaccata gaagtaatca aaacaatcat tcactttacc 173880 aagtatcttt ttaggtttac ggtcagcaac aacaacagag cctttaggga agaagaaacg 173940 atagaactcc tcttcatcca ccaccactgt gtccactttt gttggactta agtcgagcat 174000 cgttgtacaa caactaaccc cgtaggaaac attatcggtg gtgaatagca acacaccgat 174060 aacactgacg ttggagctta cgtaagccaa acctttggaa gagtacttaa tgggggcata 174120 gacccacata tcagacttag tagatatact atcgcctgtt tcgaatagcg acgaaataac 174180 cttagcatcg tcacgtatca tctttgaagg aatcaagtta gccccctagg tattactcgt 174240 taatggtgat ttgtgcgacc atccaatcga agaagatggt caaggtggct tgctctagag 174300 ccttctcttt cggcatacct tctttaatgt tgaagtcaac caaacgaagg aactccacag 174360 tcatttcacc cttgaagaga atcgcttcac aagcgtccat gatgatacct tcgatatcat 174420 caatcatgtg taattgtaca tgatcgtaaa cgtatttacg gaactctgtg attttgttag 174480 aagcttctac atcgtcagca accaaatcag gttgtgcagt tagggcatcc ataaaaccac 174540 gaataagagc agcacgaaca gcttcgatcc actgttggtt gtctttctct tttgtgatag 174600 ttacatgacg ttcccaaacc gaaacataac gttccagatt tgacaagatg tcatcctttt 174660 ggaacagagt agtttgacgc ggatcatcgt cttgtaacag gaacatgcct tgtagggctt 174720 ctaccgtacc accttgcgat tggaattgct gcatcacagg tgcgtatacg tagattaacg 174780 taatttgatc gatgaaacca ataccgccaa tcaactgacc ttcttgaagc gccatctgat 174840 agttagccag gtattcgcga acccacgatg ccaaaatgtt agtgttctta gacattaatg 174900 cagcgtaagc atcaagactt aacttggtat tttcccaagg gcgttcttct gtagcagcac 174960 agattagtag aactgccaac agacgatcaa atgaaacaaa ggcttctgat gaatccacac 175020 gcgggaaacg tgtctctgac gcgtatttga agagatcagc aaaggagtag ttgtatttct 175080 ccaacacttc tttaatgatt tcatcgtatc gctcgtgacc agtgataatg acggtttctt 175140 gatcgatgtg tggataaact agagcagagt catcatggtt aaagtcaaac tccaccacat 175200 cagacaatgc tgtcaacatc ttcccaacaa tcgggtcatt ccaacgctca tcaaaagcca 175260 ctggtacaac ttcgtacaat gagtcaatga tatctttacg tgttggaatt tcttcagccg 175320 atttcagcac ttggccaatg aatggtttaa cttggttacg tgaacgatca agaataccag 175380 aaaccagact gcgaatcttg tttttacaga acaccagggt ctcttcatgt tctgcaattg 175440 gaattagctc atcgccatca gttacatgcg cattggttaa accagtacca agtccacgct 175500 caagagaagc tttgtatttt tcaataaaag tctccgggtt ttcttgtgac atttctgcca 175560 atggtgtgta accagctgca actacgacgc tagcagcaga gccatcaaca gtaccaagac 175620 gtaggccagc tgtgttcaca ttggccgcta aaagaccaat cgcatcaaat gtaccttgct 175680 gaatcatgct agcgttctcc cagttttgtt ctcgattgtt ttaccaagtt ttgctgtgaa 175740 taaaccacga acttgttcgc gttgacgttt accactgcct tccttagttg aatgaagatt 175800 tggatcaccg tttagtaaat ccatcgccac ctctgtggct aattccgtca cattcgcaag 175860 aatgatgata ttgttcaatt tacttccgct attcatcttt ttaacctcta aaaagcccat 175920 aagtgcatga tggttctcat gtaaaaaggg gtaaatgtat atttacccct aatagtacaa 175980 cttacgagtc tcgaatttcc cttgcccctt cggcaagacc catgctgaaa cgtgtaccca 176040 aacccattcg atataaacta ccaacgatac ggttatccac accctcgcga ccaaacttca 176100 aatgaacttg acgaccagtg actgtctcgt tcttcccaac catacgtcct cgcaccaccg 176160 acttcatctg gttcgcaaca acaattttat caccaccgat catctcatgt tcacctgtga 176220 tgtaaaaacg aatcagaact tgcccttcta ctaatgcaga accaccagtt ctaaattcct 176280 catcaactcg cccagtctct gcttttggaa catgggaagc cttagcttct tttcttctac 176340 gtctgtcacc tttacgaatg atggcctgaa gtgtttccga cattaaatcg atttcaccgt 176400 tgtagatgat ttcaattttg tcaatgatac cttttgcacc agcccgtggt gagttagtag 176460 aaagatcttg aagtgtctca attgcatcag aactgaaacc gccgtaatcg ttagtgtcgt 176520 cgattaaaca caatgttgtg tcatactcaa ccacggttcc ttcattaaga agctccaata 176580 tagactggtc tgagttaaca acaacatctt taattttggt agttcttgtt gtgagttctt 176640 tcgccttgtc ttcagagatc tcatccgagt cctcgtagac ctcttcacca ttaattagcg 176700 ctacgttaca aataacaccg tttctccagt taacctgggt tgggttcatg atgtccggtt 176760 caaaagattc agagcaatag gctaggacgt ctcctttact aaatttctga cctttcttaa 176820 catgcggtac tttgtcgtgc ggatagttag tcccttcgta agacccatac cagcgaccta 176880 aagaatagac ttcttcagta ccatcagcat attttacccg tacaccatgt tcatccaagt 176940 caataacttt accatcgtcc ttagcaacgt tggcgtagta atcggaagca cggtgagcaa 177000 ctaatttttc actacctgtt cgatatggtg ggcatttgcc atgcaaagct tgtgtggctg 177060 aacccatttg aatgttaacg aagttaccac gcttggaatc atcaacgttg acatctggtg 177120 ccaatgagtt atagaaactc aataactgcc cgaattcaag ttttgataaa tcctcttcaa 177180 cctttaccat cccatcgata tcgagaatgt tagggtcatt agaagccaag gctgtgatac 177240 ccacgtcggc gttatccacg gtgtcacctg agattatacc gagttctttg gcatcgtact 177300 cacgtgtatg tttcaccata ctacggcggc tacgtccatt gctaccaccc atcgttataa 177360 catcttgctc tttgatagac tggatagcgt tagcgtcttg tgccgttaga acagatggat 177420 cactatctat acgtgcccat actgcctttg gtttaacatc caacttacga gtagttggtg 177480 gcgagttgtg gtagcgtcgc attgctttag ccacttcggt gtagaggtga ccagctaagc 177540 ggtgattaga gaagatatgc atgtattcga tatctgtctc acgagggtgg tcgtgggaga 177600 caagtaacga gttagcacga atgaggagtt tcttaaagcc agtaggctca ccaatcttcc 177660 taagtaactt ctcatgaatc gcatcaacga aacctttctc taacaaatct aattctgtta 177720 gatactctgt gccaagtttg ttcttttgta acaacaaagc ataagctgat ttcgtttcca 177780 tgtctctcaa caacagagtc ttcagctggt ctttgtatct tataaagcag ttgtataaga 177840 gctcctcctc gtaactctta ggatagattt caagtttacc ttcttttaag gataggataa 177900 taccatcacc ccttggtttt tcacctggtg ggtagaactg atactcagta ccagtctctt 177960 tcattagacc cttcaggcca agatagtaag acaagataat cccaagagga atagctttac 178020 ctagaatatc gacgtcagta tgaggtctcg gttccttgtt tgtcggtaaa tctaattgct 178080 caatcaaacg ttcagttgga gtaatcttac cattctctaa cttatacaaa gctgaacgct 178140 cgtccattgc aagagtagtc gttcttgatt tggccactgg aaccagattt tccttggtaa 178200 gtagcttgac ttctttttcg tcaaagacat caccaatctt agagtggtcg aaattgtaat 178260 ggtaaccttt agagtcgaaa gaagaaatct tcatagcgac tgtggtgtaa tcgcgcggta 178320 acttaacctt gtgatcgaag acatttgaaa aactaacatt cgtgatggtt gggttatcca 178380 tatccacacc acgtgcagta atttcattac gaacccactc gccccaattg accacggatt 178440 gctcagaggt agagacaaac aacttaccat aaaagcttgt tagagcaact tcactcggac 178500 taaccttacg gattggtaaa tcaacacgtt gtttacgcat tgtgtattta acaccgttgg 178560 atgtccagta gccatctttg tctacctttg gtaagatgaa agggatcgtt gcttgtgtac 178620 cgtctaacaa ctgaacacgt aatttatgct cttcgcggtg accacctgca tcaagtttct 178680 cttgcatctc atgagctgta atcaccatgc caaacttctg taaggagttg gtgattttaa 178740 taacgtcagt tttaaggcgc ttggtgttgt actcttctgt gtagatttta gtgcgtgagc 178800 cattccaaga atcttcaatg attgttgggt cgtcgatgaa tttctctttt tcaatgagaa 178860 tttctttttc tgcgtttctt agttcctcac cgtagctacc accataagga gattccagat 178920 tatcaacctc gccaaataga cgcaggaatt tatcatggcg tttaggtgac acctgcttga 178980 tttgctcaag atcgcgtttg ataatatccg aaacagatga gtcatcttca gtatttacaa 179040 tgatttcgtc ttctgttact tcttcaacaa ccaactcctc atcttcaatt tcttttcctt 179100 cgaagcgttg aatttcatct tcgatcaatt catcgtcgtc ttggaaatca acatcatcct 179160 catcaacttc tgaattgatg tcaacatctt taccctcagg tgcagccttg aagccagtag 179220 aaaccgcagg tgtttccatc aagatacgaa tggtttcacg gaaacgttta accatctgat 179280 ctggcgggac tttaccttca cgaccttctt tacgccaacc gtccaactca ccaaggttga 179340 tgttgatgaa gttaccgttg aattgcaata agaagttaac atggcgtgcc ttgcgagaat 179400 caatctcact aaacatactg ttgtttctat catccgacaa ccattggaaa agttctacaa 179460 gaactaacat ctcatactgg gtatttcctt cccacacggt ttcagtgtga gtgttcgcca 179520 ttttgataaa acgtttacga ctaggtaaga acttaggaag gttcagtggg atgtagtgct 179580 ggcgttcagg gtattctgaa attgaatcca aaacaccacg gattaaggta ttcagcaagt 179640 tgtgcgcttt gtcgtaccac acgttgattt tgtcattgta acggtagcga cgcaggattg 179700 gtgtgtagtt ctcaacaaga actattttat tgtcggttga taaaagacgc ggatctttca 179760 atcgtttgat ttttttccac ttacgatggt aagacagaat gtcgtctttt atctcacgtt 179820 tgatttcaat aggtagaccg acagaattct cagcacgcat ctctaagtga tgacgcatac 179880 gtgcgggttt ctctaggtcg ctaagatgat ataatgttgc aggtggacca aactccagac 179940 actctgggtc tagataatgt aatacagtac cgcgtgcaaa ctctaattta gcaagacctc 180000 tgacttcagg ctcaccaaat tgagttagac gtctgaccgt aaaacgacgg ttgaagtctt 180060 ttaagagaat cattgtggaa cagctcccat gtttttttac ttaacctact cagggtcttt 180120 cattagtgat ttaaatgttc gtttagctgt gccatcgatg agctcaattt tgagtttgtt 180180 gttcacgtca acccaataac tgatttcgcc cattcgcttc ttctgttcct ttaacgactc 180240 ttcggtgtag accgagttac cagaaccagt atcgccatcg tagtcacctt gcaaacccgc 180300 aatacgcgta gagtgtggtg ccatcgcaga gatgaactct tccacatctt ttctagggta 180360 agatatggca ggtacttctc gcactgtttc ccaatcgtcg ttgtattcgt agacaacgtc 180420 tgatttaacc gttgtctcta cacgtatagt agaaggatat gtactaccag agcctgctac 180480 cgggtaacgt gtaacgaaca tgaagtagtt accccaaatg tcataacccg acaagtagag 180540 taactcagct aatgtgatgg gttcgacata cttcctatca aagccatcag gtaaatcacg 180600 aatatcgcaa aatactttaa atctatcgtc tttacgatac actaatgcaa tgtaacggtc 180660 tgctacttta agaggagcat gtcgtttttg tggaaccctg aaactgtgta atagtttctc 180720 aataccttcg tcggtagtat ataagtcgta gtctttaacc ccgactttaa catactctga 180780 ctcaagagtt ttaggattga tgagattcat atgaccttga cccgcatcag cacggctcaa 180840 gtatcggttt cgaacgtaat gttgtgtaac tggtaaaatg gagcgtagac cctgatgtaa 180900 accaactaaa gtatctgtcg gtctgtattc atcaggcgca cccatttcag ttgaactggc 180960 gatgagtgga cttagtacgt tacgtgtacc atcggtcaaa cgacgggaag taactttacc 181020 acgagtaaat ccctttttac cgtcgataaa attaaagaaa tactcgtata catcgatgaa 181080 ggctttttga agtttccatc gagggatatc catcaatggt gaatcaacac cgcgctctgg 181140 tattgttttt gcaaccgtca taacggaacg atataatggt gttaactcat gctccttctc 181200 tccgttctcg tctatctgca tatcgcgtag accagcaggg aaaacgagca cataagggct 181260 gagtgcgaac tctctaaact tatagaagaa gtcaatagac tgctgtcggt tttgagagtg 181320 gttctcttta ggggtcagtt cgtggaaatg cttaataaaa aagctataac cagtatttgc 181380 tccagggtca ccctgctttg cgctgtcgaa gtcttttgtc tcttcgttcc aggtagcaaa 181440 tgcagtaccc gacattactc ccttgtatag ttgctttaac tcaaaaagag ttagagcaat 181500 gataggtgag atgatactcg ctttggcgtc tatgtaagag aagtttttgt cgcggttggg 181560 tgagccaaca ggaccaaaga tttcaggtga ataaaaacca tcggggtgaa agttttttgt 181620 ggcacctacg tatgtgtcta acgtcgtaac aggacgtaac ttagacacca tggtcttatt 181680 cacgtttaat agataaatgt ctaataacac aacttgttcc ttaggtggca cttatgagtg 181740 atgatatgga cgatttggat aaactgcttg gggatttaga tgatgatttt tcatcagaac 181800 ctcatggtga ctttaagtca gatgaccgaa aggcagttac taaggcagtg aaaggtgccg 181860 cttcttcggc attttcacgt atccttccaa aacgcaaaaa acaagaaata atcctcaagg 181920 cactcccaaa aaattatggt gaagctgccg acaatatgcg ggatattaaa tacacggcag 181980 acgatttata ttctcataca aaagaggaat tgcttgagac taaacgccaa atgaagcgta 182040 agactcaagt attaatgcca acacttagaa agtacctacc aactccaatt tccgaacgtg 182100 tggacaaatg gagtaaacca gaagagcgtg gttaccgtgg tgagtacgat gaagaacagg 182160 ctaaaattga ttcagcgatg gcaagtgtgt ttaatagcac acgtgagagt gttgttccaa 182220 cagacacacc gcaagccaaa cgtgcccgta aacaagaggg cgacgaagaa ttacaacaac 182280 gtaccgaaga agaaattaaa gagttttcta gcgatcaacg acagttacaa atagtcgagt 182340 ccaccaaacg catcgagcgt ggtgtagaag ctattgttcg tcaagagcaa ttagtaggga 182400 catcgtggaa gagaaaaact ttagaagtta gtcttcgcca gatgtttgca ttgcaagaaa 182460 tctcagcatt aattaagatg cagaacgata gaaatattcc agcgatggaa gctatcgtta 182520 aaaacactgc tttgcctgat tacgctaaag agcaatttag tgaagttgca gcagcaatga 182580 tgcaacgcaa aatcattgag tcaattaacc caatggaata ttcacgaaac ttcttaagcc 182640 gctttgcaga taatgcgaag aagaaggtga gtgaaacact tggtgaagtt cgtagtttga 182700 tggatttggc tgataccatg gccgatgaca cagactttga ctcgggcgat actgaagtta 182760 gtgaagacca acgtaaaagt aacttacgtg accttacctc aaatcagtta gcagcttgga 182820 ttgcagaacg tgtagctgtt ccagtacgcg acaaggtact taagcgtgta cgtaaagcgg 182880 cagaaggtaa tgacaaggtc gttgagttcg gtgagaaact acgttattac agcgggaacg 182940 ttgctcaaat ctataacact gagttgacag atgaaactga cgactctatg ttaaagacca 183000 ttgttagtta cttagaagaa attcaaagtg gttacaatgg cgagttaaca aagctacgtg 183060 aacgtgatga gtcctggttg aacgaatccg ctaagaacga taaccgtaaa tatatcacga 183120 taacagaaat catcccggca tggctagccc gtatcagtgg aggtattgat aagttaaacg 183180 gtggtaatgg cgacgatgta gaatacgata ttcaaactcg taaattcgtt aagcgttcag 183240 tcatcaatga ccgtgttcgt gatgtcgttg gtttacaaga taagaaagat gttctaaagc 183300 aaggtttgga tggtctcgtt aaaatgttcg attcgaacaa tgagctgtct gaacaaggtc 183360 gtaaggaact gcgcgattac ttctacgacc gtgttagaaa gaatagaaca tttgacatca 183420 aagatctagc agcaagaccg ggtatgcaaa gaattgtcac agagcaagct gacgatgagt 183480 ttttcaataa gcgtattcaa gaacttgctg gtgataatct ttataccaac atgaataagt 183540 acgcatctcg ctttggtgcg ctacgtggtg cggcgggtgg atatcagaat gccattaatc 183600 agatgtctgg gttatatggc gataaagctc tagttgatgc aggtatcttt aaaggtgatg 183660 ataaaggtcg ccttaaagtt gacgaatctt tgtttgattt agataaagag tatgtcggca 183720 gtgcgactaa aaatgatcgt gctatgagcc gcttcatcaa tggcggggct ttagataaca 183780 aactatcgcc taagagtcta gatagaatta aaactatcaa tactgaaggt ggtaattgga 183840 ttaaaggtat ccgaaatatc aatcaagaaa aggcaaagcc aaaagccaag cctactccta 183900 aggttgagcc taagcaacaa cccgaggtac aagccaccaa taccacgagt aacaccgata 183960 acactaatta ctttaaacgt attagtgaag gtctagctgg tttgcaaaaa tcaatcaatg 184020 gcgttaaaac accaaaggtt gaagtgaagg gtctagagaa catcagacca cctatcgatt 184080 acacctcgaa attcgataca atcatcgact tgcttaaacg taacgcagaa gggacagagg 184140 aaactaaacg ctcaatcctc agtatgttga aacgtaaacg caagagcgat gatgtggaag 184200 aagacgagta cgcaccgggc ttctttaagc gtatgattct taatcgacgt gctcgtaagt 184260 tgaaagagaa agagtatgtg gagaagaagg ctggtaagga agaaccttct gcatttcgtc 184320 aaaggtttga tagtatctct ggaattttga gaggtggtgt taatactggg tttgatttcc 184380 ttcgttctgg taagcgtggt gttgaggctt tcgttaagtc tgcggtaggg gcaagagaca 184440 tctacggtaa agatggtaaa gtagttctat ctggctctaa gttagagaag ggttactact 184500 acaccaaggt aaacgagaaa cttacacaaa tcttcaaact tgaggatatc aaaggcgctg 184560 tttatgattc tgaaggaaag gtaattcttt ctgaggagga cttaaagaat gctggtgagt 184620 tgtcgtacta taaagacagt cgttggtaca aactaacgga ggtcattggg ggtaaactcg 184680 gtgggggtgt aaatgccatc acagggatgt ttggtaaggg cggagcaccg ttacgtgctg 184740 tcggtgataa gatcatcgct ggtgtgtttg gttaccctga tatttatgtt aaaggtgaga 184800 agaccccacg tttacgcgcc gagttcatgc gtaagggatt ttaccgtcta aatggttcag 184860 acggacctgt tgttaaagga ccatctgata tcaaaggggc agtttacgac atcaacaata 184920 aactcatcat tagtgaggag gaactagcct ccgatggttt tgagttagta gaccaagacg 184980 gaaatcctgt aagaactcgc ttccaacgtt tcaaccgcat ggtgtctagt caacatcgtc 185040 gtgtccgtaa attcatcggt gggaagatca catcgattaa aaacttccta gtaggtaaga 185100 agaaagagga tggtgaaggc gaagagaagg aaggattctt ttctagacag aaacgcagac 185160 tctcttcatt ctggaaaggt gatggcgaaa aagaagatac cgagaaacgt cgtggtatct 185220 tgagtcgcat cttcggacga gcaaaggatg tcgcttacgg cacttcagac gagtacaatg 185280 ttctcgttaa gatttacaac ttattgaata aacgtctacc tggtgagcca ggcgatgatc 185340 tcgaagaagg aaagagccac tttggtaaag cgaaaagcac tatcaaagat aaggtgagtg 185400 acttcaaaga gaaacaagca gcaaaaccag aaagacaacg tggtgtcaag aacttcttca 185460 agcgccgtgc taaattggct gagttgaaag ctaaacgcaa aatgcgtgaa gttaaagaaa 185520 cggacacttt caaaaaggca agggacaaag ttgaagagct gaacgaaaac acagcttcga 185580 aacgtcgcta tgcaagaatg aaagcgaaca aggctaaacg aggttttatg gatcgtttaa 185640 gtcgtggtcg tcgtttaaca gaactcaaag ccaagcgcgc taaacgtagt tacgaaaggg 185700 accgtacacg tttaggtgaa acagccgcag ttctgaatgc gggtaaagaa gagatataca 185760 atccagtcaa gaagttcgtg gtgagtaata tccagaaagc taaacgcaag atggaagaga 185820 agttcgagaa acctcaggat aaatttgctc ctatgaaagg taagggtgct ttgaaagacc 185880 cacagcttga acttcttcgc cgcattgccg actcttctga ggcaggttgg attaaatcta 185940 tcgcagagtc tacagacgac tatgggatgg accaaggatt caagcgccgg gctatcggag 186000 acttcgctag gaagttcaag ggtggcctaa gtcgtttcta ccgtgactat gctcgtaagg 186060 acaccaatga ttttggtgag gagaaagtca aggataaaga gaagggacct aagaaagaag 186120 gtaaaggtaa gaaagaaggc ggcttgcttt ctaaattact tggtgggttg actggcggta 186180 tcggtgacct aggggattgg attaaaggca tcattgctgc taagatgggc ggtagtctat 186240 ttggcggcgg tattaaagaa ggtgccaaat ctttacttaa gtcgggtgct aagaaagtag 186300 ctggtcttgt tgcagggcaa ggattgcgca cagctggtgc tgcactatta tctggtgttg 186360 gtactgtgct tggcggtttg tccttacctg tggttgcagg tgtggctgct gttggggcaa 186420 ttggttggtt tgcttaccgt aagttgacaa ggaaagaagc tggtcctttg ggacgacttc 186480 gcttggcaca atatggtgtg cgtgattacg acaactggaa ctctgaagat gctagtaaga 186540 ttcgctatct agaagacaac ctaaagcgtt ttgttacaat tacgcctagc ggtgccaccc 186600 ttaagggttt aacggctgag aaggccggag aactcgctat aggttatggt atcgataaag 186660 aaaaccaact tgaagtaaat gcttggcatt catggttcca aaatcgtttc atcccaatct 186720 atttactgtg gcaaggtagt atcaactcgg tatcaccaag cctaacagtt ctggatgtgg 186780 aagataagaa tcttgacgca gaaacacagt tgaagattct taatggtgtt cgcttaccgc 186840 ccaaccatcc gatctttgct gatcgtgccg atccattgaa ggccgatcgt gggtggttta 186900 agagtgctac tgatttcctt ggtttcacag aacagaatct tctttctggt gaagaggtag 186960 gtgatgtgac agctcgtgct attgaagagt tgcaagggaa agctaaacgc gagaaaaaaa 187020 ctgaacaaga ccgtgttaat aaagaagtcg gcgtgcgtaa gttcaatgaa ggtatgatgc 187080 aaaacaccaa accttcgccg atggattcac ctaaagcaca agaggctttg aagaatatgt 187140 acggggcaaa taaaccgact cgtaacttct tcccagggat ggataaagcc gctactggta 187200 actcggagaa agtgaatgtt ttagtacctg ctgttgaaaa acagggtata cctgctactg 187260 ttgaaattat tcgctttgcg atgtacggta ttgataagcc aacagatacc acattggagg 187320 ctttgagaaa gctggataaa attgcagcgg acaaaatcaa cattaaatct ggacaaatcg 187380 atgaccgttt ctacggtgaa gcgatgactc tagcggcagg gttcggagta gtcacttggg 187440 tttcagaaat taataagtta gatagacagc aatataaaga ctggttacgt gaacgttaca 187500 tccctgtctt tatagcttac aacaaggcca ttggtaatag cgtcggcatt ggtagtgttt 187560 tgaaccctat gccatcagaa gacgtgtatc gtgctatgaa ggctttagtg gggactaagg 187620 tatttgcatc attaggccca gtaagtgtgc ttacaatgcc atctggtgtg aataaggttg 187680 gtacatacac cattattaag gatagtgcac caatcgacaa acttatcgag tcaattaagc 187740 cacccgagaa gcgtagtatg tcttcgacgg tcactgatgg tgtcgataag aaagttaaga 187800 aatcttacat ggatggattg acttacaaag agcgcgggga taagaacact tcagtgatag 187860 caagagaacg tcaaaaacaa atcgcagatg ctaataagca atacgatgag tataagacga 187920 ctactgcaca acaatcactg gctcctcgca tggaccctgc taaaatgact agtgacttgg 187980 ggacaggtca atatgccgag tttgcgaaga tgccactgaa gagccgtgaa gacgtcgcta 188040 ctttagttgg ccgaatcgca aaggcacaag gcgtagaccc taacttgatg atcacaacag 188100 cactagtgga gtcgtcacta aacccaacag ccaaggcaaa gacctcttcg gctgctggtt 188160 tattccaatt cattaataag acttgggatg aggtgatgag aaaacatgct aaccgtttgg 188220 gtattccagc gggaacgcgt gcaaccgacc ctgttgcggc aacactgttg gctagcgaat 188280 actttagaga gaatgggaaa attattagct ctaaggtgaa tcgtgatttg acgccagctg 188340 attactacat gggtcacttc ctaggtgcag gcggtgcagg aactttcttt agtgaaatgc 188400 aacgcaatcc aaatgctatc gcagcagaag tattaccatc ggctgctaag gcaaatctca 188460 atatcttcta tgactcttca actggcagag cgagaacttt aagtgaagtc tatgaattat 188520 tcaccaacaa gttcatctct cgtggtagtc agattggcag tttgactaga ggggagttca 188580 gttcatcttc aggcgtgcag attgggttac cttcccgtgc acctatcgat gacccattgc 188640 gtcgtgagga agcggttgtt tctaaagcga agcgtgactc tgaacaatct cgccgtgtgc 188700 gtgatggata tcgctcagta acaccgggcg gtgcggagtt tgaacttcaa tcgacagcac 188760 aagctaaaga gtacgtagct aaccaaaccg aagctgtttc aaaagaacag ccctctatga 188820 agctaagtga taaagagcgt tacgctactg cactggctga agtagaaagc ggtgtggagc 188880 cgacaaaacc aaaacgtgaa aatgttttgt atgacaaatg gtttaaggac agcgcagagt 188940 atcaatccaa agacgctgtt gttcaaaata accaattgca ggcacagctg cgaattgtag 189000 agattcttca attcattagc gagaagtttg atttggcttt aaataatatg gggacaaaag 189060 tacctagcga cttaaatgtt gcagagaaca ctgcggctgc ccaattcagc cgtcagaaaa 189120 tcaccgtaga tttgagccaa acaaaaacca atgttgctag aaataaaaac gcttagtgtt 189180 agggggactc gttccccctt ctctatttaa tttcggaagg agacgttatg agtatgcaac 189240 caagaaccaa agaccttatg tgggttaatg gtctattcgg tttagcacct cgtgcaaggg 189300 attctcaatc ccgttctcaa cgtcgttaca gtaatctgca tttcaatttt gcagacacga 189360 ctattggtgg tagccaggct atcaactgtc caccgcaatt cactgccact tgcgatccac 189420 ctttcactgg gttatttgct aatccagaag gtcgtactga gggttctcgt agcgattact 189480 ccgacttatt tgcaggtgag cagaaccaag gtagttatcg aatgggttct ttcttttttg 189540 aaagtattta cgataacgct cattttgtac attgtcgttt cggtaaaccc aaatacaccg 189600 ggatgattaa cttctttgca aataactacg actctaactt agctcatttg gctaaaacgg 189660 gtgactacaa ctctttcgcg cgtaacctag gtgcgtgggc tggcgcagct gccatttata 189720 gtgtggtggg gcctttggct ttcgttacac tgttggcggt gccacaggtc cttaagttcg 189780 cccttggtcg taaaccgtcg aaatattact atctcaaacc aaccatgcac acttatcttc 189840 gtgctgtcca gtctatattg gatacacaag cattgcatta tcgcttgttg ccaatggctg 189900 agatattcgg gcgtgataag tacgagtatg agatgacaga agagcaacgt aatgaagttt 189960 atggtatgct cccagatatc tggaagtcga atggtaagtt cgatgtgtac aaggccatta 190020 accgttatca ggttctggct aactaccaag ctcgccaact caacgctatt tacgaagcgg 190080 catctgatgc tgacgatttg caaaaccgtc tacgtgctca tatgcgtcaa gcaaagacaa 190140 ccgctttgta taagaactat gctactgaga acgaaacgac ccttcaaaag ttggaagatt 190200 tgtataaggc taaccccgct taccaatcag agaacgttgt tccccctggt acagaagagt 190260 acgctaagca aatggttcag aactacgaca agcaacactt cgatgcggct agactgcaag 190320 aagaacagcg tgtcttacag atgaacacaa cacttgacca aaatgcagcc gagtacaaag 190380 tggctacttt ctgggaaggt atcgttgatg acgtatccgg tagtttctct gatatagcag 190440 agcaatccta ctctgagttg aaagatggtg gtcaatggat ttcatttatg atctccaaca 190500 aggaatctat ttctgattct ttcaccagtt caacacgcga acctgaaatt tcttccaagc 190560 ttaaaggtat agcttctagt gcaagaagta tagaagttag cacatctggc ggaaagacgg 190620 gatttgagtt tgtcgacgca gctatgactg gtgtcgctga gtttgttaag ggtgcagctg 190680 atgcccttca tctaacaggt ttgatgtcgc tgtacggtgg ggcaatcatt gacttccctg 190740 aagtgtggga tgactcgaat gctgagattg gacagacaac cttaaacttc ccgttgcaat 190800 catggtcagg tagtgatttt gatttgtttc aaaatatcat ctttccatta tcgttttggt 190860 tagcggctgc tatccctaac tcaacaggta gtcaatctta cacccacccc ttctatgtag 190920 aggcttactc tccgggtaag ttcatgattc gaaatggtat cattaccaat ttatcaatca 190980 ctcgcggcga aggtaatgtt ccatttaaag cagatggtaa aatgttaggc tgtaccttgt 191040 cagttactat taaagatttg tccaccgtga tgcacatgcc tttgattaac gacccgggta 191100 ttttcgatga cgactctatg ttcactgact atatgtcaat cttaggcagt gcgagtttgt 191160 ttgagatgac caacggtttc caaaagctga atatgaactt caacaaatgg cgtcaatcgt 191220 ggaagtctgc tgccatgact ggtaatgtga cttctagtgt gatgaactca gcacctgcac 191280 gggtactggc ttcggttatc gctggtggta actaccgcta gagacaaaaa aaagaaagta 191340 ccctcgtaat gagggtactc ttttattttt ttatccgtta acagtgagaa tgacaactaa 191400 aaaggacact cattgtcaat cattcttctt taggtagtca gataacccag acacttcaat 191460 gcacccacgc aacggcattt cgccatcgtg atcgattgtc ggcatctggc aaatactttg 191520 tagattagtt attgaaattg ggaactccat tatgggaccc acccccaaat ccggaagcgc 191580 cttagcgacg attgtggttt ctatttcata cgccactaac ttacaaccgt tagtccaacg 191640 tttcatccgt tcggagtttt ctaagtagta agacggtggt cgactaattg tttctttcgt 191700 tacaccttcc cacggcttaa tacgttttgc ttttgtaggg tctttaacgt aatgtggggt 191760 tgtagtgtgg atttgctcat ccaagtataa gaacaatccg tcctcttctc tttgaatcaa 191820 caaacaaatt tcggtttctt tcatttttga tattccttgt tatccggcgt ctagataaaa 191880 gtacctcctt gtgtaggcaa ggaggtttaa cttatttctt tatggctatc agttcactga 191940 ttggttttct agacgatgct aaacaactaa tcgtgcgctt cgctggaaaa gcaactatct 192000 ctagtccctt gtacaactca cgcgtgatat cgttgtcatg attggatata gccaatggtg 192060 ccacagaacc ttttgaaagg gtagctaagt cctcttggtc cttcttagtg aatccctctg 192120 tgctgtaaga gacgaaattc gccgttgcac tcgatggaac ataaggcggg tcagaatata 192180 caacatcatt atctttaact tcagagaagg tctctctaaa accttgacat ttaaatgttg 192240 ccttcttagc cctctcgcca aagtaacgta tttcctcttc tgggaaatag ggttggttgt 192300 aagcaccaaa cccgacatta aacttaccct ttttgttata ccgacataac ccattaaaac 192360 aatgtcgatt caaatagata aataacagag ctttaaagta ggtatcggta gtctcgttga 192420 actcatctct taaccgaaga taaacctctt tctcgttcat atcgggagta aagaactctt 192480 tcaaatcact tatgaatttt tcatggtcgt ccttgataaa attataaaga ttaatcaagt 192540 cagggttgac atcacataaa agatattcat cgtagtcaag gtttaaaaaa acaacggccg 192600 aaccaacaaa tggctcaacg agtcgctcgc cagcaggcaa atagttttct agtttatcta 192660 ataaactata cttaccacct gcccacttta atggcgaacg gtgtctgagg actttagtca 192720 cttaccgcga tgttggcacg acgttcccag aagtcactaa tctgggcacg gtcagtcgga 192780 ttcaattcct caccctcaac gatgatactt tcgtatttga atgggatgat ttctttaacc 192840 cggtcagttg tcatgcggtc aacttccagc tctaccttaa cccaacctag agcttcaaag 192900 cccttgcctg agttgtagaa tacatcgact tcccacatgt actgctcacc actattgcga 192960 agtagcggtt caccacgatt agtgattggg atattgatac gcgttacacg gtgaatgttt 193020 tcagcgtaac gaatgtagct ttttgccacc ttagttggaa tagtgatgtt atcttcgatg 193080 ttatgaccat cgggatgttt cgtcttttcc gtaaaggtag cactttcgcc ttcaacacga 193140 acacgtgtgc ggttaggtaa acgtttcagg aagatgtcga ggaaatggcg tttggtctta 193200 agcgccatta gttcatctaa cgtctcctgt gttacctgac accaaaacac atactcgtgt 193260 tcttcttcga ttgaacgctg gtcttcatcg agtagtccag ctaatggacc ttttctttct 193320 ccagacacgt taactcctta ttcagcagtt gccagttctt tgatgtgctc catccacaaa 193380 gactgctgcg ccgacgtacg atgtcggtag ttcaaaccaa atgtgaattt gcgcggatcg 193440 tagttgttaa actgctcttc cttaagttca aggttaagag ccttgtctgc ctgtagacca 193500 accgcgatac gataaccttt ttcgttatag tgtttgtagt ttaccagaca gtagctgacg 193560 acgtcttttg cttcgtcttt gctaatttca atgtcgcgtg gtttcatgag aaactcatct 193620 tcgcgaagga tagcttcgtg atggattacc gccattgcgc gagtcatatg ttccatctta 193680 aaaccagtct gatgagcaat aagtgccatc gccaagtttt tcaatggggc aatgtcttta 193740 ttctgttggc ttaccacttc agccatcgca cccgctgtaa tagttttgtt cattttaaag 193800 ctttcctttt aacttagatt tgaataattt ggcattgttt gtgataacaa cgtcgcagtt 193860 gtcttaggct tcactttaga gccaatgtat gctagaattt tgtaatcggt agtagcaagt 193920 actttaattg catcatccga gcagaaagag aaataataag catattgctc attagggtca 193980 taggggtcga gataccaatt atcatagacc atcttagtga tgtccattaa atcagccgcc 194040 atagccttaa gactcatatt gtctttaagg tcatagaact gcaacaactc aaccaaataa 194100 cgctcacgac aagcgtattg acggtcactg tgtaactttg gccatagctt acggaaacat 194160 tcgaagtccg acatccgtgc agcggtcgac aagttacgtt ctattgatag ttgcgcagct 194220 cgtgtatccc acatcaagcc tgttatttgg tcgatgtatt ttgggatacc ccattcaatt 194280 gccttcgacg taatcgcatg tagtagtgct atttcttcag aagcattgaa aaaagtaccg 194340 agttcttcat taccagagag ggtgttaact aagccaaaga ccccttgtga cattggggca 194400 tcacctttgg caaagtctag accttcttct gtaacaaaag cagccaatcc catctgttta 194460 ctctcatcag agtacccgag aatgttaagg aactcgctcc cagttgttaa caagtcattg 194520 gcttccgcct cactcaattt actcaagtca ttcgaaagac caagacgttg tcctgcccgt 194580 tttaaagctt cagggctatt gaaactagcc ccgtcttcaa aactaaccgt tgacttgaca 194640 tcatctggtt tgattttacg taaagggcta ttctcgccac ctaggatgtt tttggttttc 194700 tcccacatgc taggttcttc gacaggtgca gggcagtttg ctgttgtaaa gggcaaacct 194760 tctggtgcaa ctggcttact ggctaatttc agctcaccat cgaccacttt gtttgggtcg 194820 atagtttggt taaccacccc actctccact aatgtggagg tggagtctgt gacaggacgc 194880 acgtagtccg gtggggctac gcgcttgtca ggttgaacat tgggaagttc ttcacgcttc 194940 ccagagttga atatagttgg ttttacttta ctatccatcg cgttttacct taatgaactc 195000 taactcactc atatctatat ttaaactagc gtcgaatgta tcatcggact ctgtcgtcat 195060 ggtgatgttg attttcatct catggatgtt gagtgcttta actgcttggc agaatcgcat 195120 ccacgacaaa ccttcggtgt tacaaacgtc gcgtttaatg ttggagtact tgtcattacg 195180 atagtttcga atttgttcac agttaatagg gtcagataga tactgctcca ttaacttatg 195240 ccaaacctta ctagcgttaa acttgtctac caacccccag tatagtttac ctaaagggtg 195300 cttcatttca gagatggctt ttattggatt ttccaaataa ccatctaatc tagatgaaac 195360 acccgggttt ctatcgtcat cattacgact ttgattgata aatgataatg tagggttaaa 195420 tgagatagaa atcgattttt caatttcagc tatggttagt ttccgcttac acactaactc 195480 gactgtaact tgtttagact ttagtaatac tagtccggca actatacgtt tccaagttac 195540 ttccttaaca gaatcttctt tttgacttgt tcctcgaaca agagcaacag ttaatctatc 195600 acggagttct cgacgtctag cgggagtttg ttgacaaaat ctttcatctg atgtgaagtc 195660 attcatcaag cgttcccagt ctttcggttc tttgactatt tgtgtagcca aagcccagaa 195720 tagatagcgt agcggaccac ctaactcaac agggtctagg tttttaccct ttccctcgat 195780 gatatgtttt agattcataa tcacacccta tctggttctt gaacttatta aattcagcgg 195840 ctagtctaac agccatgata ccagcgtttc ttgggtattt cgacaatgat gaatctcttg 195900 gcaagtgttc tttgcatcga ctgtacagca caaagagtct tgttgggatt gtttcatagt 195960 cgtagccgtg gaaataacgg tcacgatata cttcttgttc ttcatattca aaattcctct 196020 tttgtttaat tgggtctttg ctcatatagt ttaagaaaga ctcgacgtaa tcgtttagct 196080 ccttgaagct accgaaacca ctctgtattt tcaaagggat ttctggctgc tcctcaaagc 196140 tagcgagttt gaaatggtag tatagtttgt cactctctaa tagtttagga gagttcaagc 196200 gccacgtgca ccatctaatt accattcttc ttatggataa catatatttg aaaccttttt 196260 gcttctggga gtgattatgt ccgaagaaat taaagacaac gttaagaagg atgatgtctt 196320 aaccatgcta gccaacctta atttacagga tgagcaagct gtattagaat atgcccaacg 196380 aaaccgtcat gagctaatag agctattgaa gacttttgcc catagcggtg acaccaaaac 196440 catcaacgta attcgtggtc tattaaaaga catggatagt tcggtataca ccaaccgtcg 196500 aatccaagtc gagagcaaag atgctgatac caatgcggaa cttgcacgtc aggcggctat 196560 gcttcttgac caagcaggta tcggtgttcg tcgacatgat ggtgaagtgt cagattacgc 196620 acccgacttt gacatttctg ctatgccagt tattgacctc gatccttcag tgactagtaa 196680 ctcagatggt gttgtggaca tcgatgctat tgttgcgatg ggtctgagga agactcgcgg 196740 cgattcgtct gacgaagact aaacaaacca gcatcaacca attccaaagt aaaagccgta 196800 gcacagaact ttttggtttc agtgaaagga tttaccttat ccgcaatcat agcctcggcg 196860 gcttcttcca ttgtatctga acgaagtatg gcaggtgagt atacggtttt acccggcata 196920 cgacccctct cttcacttag ttctttgaca tggatatcaa tccacttgtg gaagtcgtaa 196980 ataaagacag cgtcgaagtt tgttttaata aactcgggtg tcaccttatc tataggttga 197040 aagataaggt caaccgatag cgtgcaacta ctatagaggt cttttagatt ctctaggtag 197100 attgcacgct cgtctttatt taacttgtat ggccaagtat tcacagttag tcttggtctt 197160 tctaagggtg tccccaccaa tgtcgctgca aacttagccc ctaactcaga gactaggcta 197220 aatagaaggt tggtcggccc agactgtttt aaagtctcga cgcttctatc atcccacatc 197280 ttctgccact cttcatcagt gattccgagc tttttaaacc acacattagt aacgcgtgta 197340 cgatattctt tcatatcgat ttttgtgtat aagtgtggtc ggtgttctaa aattaaaccc 197400 agtcgagtgt cagctaaaga atcgatatcg actagaactc gttgctgcgt tatcattcca 197460 agttgttccc taagtgcata gcccgataga tagtcccaag agttgtgaca gctttagatt 197520 tcgttgcagc caacatactt tgctctaaac tacctttacc cgtcgctttg atttcagcat 197580 agatagcacg aagtagtttc aagttaccac cacgaccttg gataaattct ttagccgctg 197640 cctcgtaccc ctcagccatt aacaagtaag cttctgggaa agacattgag cttgctttcg 197700 aaacaccact acccgttacc tggtgtgtgt attggtcaac acggcggttg tgttctggta 197760 tacttgcctt cttaataatc gactgtgttt gtggacgcgt gattagtggc agaaccatat 197820 gctcgtgctc agtcaaaata gtcatacctg tcttagagtt agttaaccaa attctttctg 197880 agacaggtag acccatttct tttaatacat ctctggcgtg gtctgttgga acttggactg 197940 gtccaccaac aggtgcgtag aatgggatac cgtcgcccga aataatctca ttgagttttt 198000 catcagacat tgttttaaat aattgtctgt agagattacc gttagttttg ctggtatcgt 198060 agcggtccat ccactttaag atgtatgcct caatcttagc gcgtttaccc ggcttgaatt 198120 taaactcggc catgtgatta ttcctttata cgtttatgta ctgtaacata agaatcgagg 198180 atatccttgg cccattgttt gagtgagtcg atgtggtcaa cgcgttgcaa gcacttagtg 198240 gctttatcaa cagcgctatc aaaatccata gtagacattg tgcttggttt gttactacgg 198300 gtgatgcgag caaatagctt aatgcaaatc tcgccagtga ttttccgtac ttcggcgggt 198360 ttaggggatg aagacatccc ctttagtttg ttagccaaac gaacttcgcc gatatcacaa 198420 agaaaatcat acaattttcc aagtgcatca ttcatcttct tttttatcct tcttaacttt 198480 attgcgtgtt aggaacttag gatgccattt gtcagcagcc atttccaaca atgagtaaat 198540 tgttaaagtg tgaacaccaa agtgtttttg gtcttcttcg aacatccacc aatccacagt 198600 cttttcgtag atttcatccc agtcgtaacc gaggtctacg atgcgctgat agatatcttt 198660 agcttctagt cgcatatccg cagggatgcg aacagagttg tttaggtagt aagccaactg 198720 tgcagtaatg gtcatagcac gagcaagctt cttattctct tcgacatcgt tacgaattgt 198780 tgtacgttcg aatttaacat ccggtaggag gtcgagtgag tagaaacgat taccaatctt 198840 ctcaaaaccg tatgggtttt tcttaagcac ttcttttaaa tagtgccatt ctgaaagacc 198900 ttgtagaaga ccttcttctt gagagaagat aaggtcgatt ttaacaccag tcggaccaga 198960 cttagcacgc cattgtgtgt agcgtacaat cttaaggtca ttgtaagaca tcaaattacc 199020 acgtgcatct tgtttaggat acattggttc ttcgatacca gtgtctgggt tgtaactacc 199080 cggttgcttc aattcacctg atgatgaggc aatcatcagt gagttggtca tgtacgtcac 199140 ttgtttaccc ggaacgttgg caagcttaat cttacctttc atcgtatcga gtttacgctc 199200 agcattgtac ttgtccattt ggatatcatc agtcaactgt actgtaaagg caatggtgta 199260 ttcaccttgt ccagcaagac gtgcccaacg acccatcatt tgagctttgt ggttgttgtc 199320 tgtcatcgca atgtggtttg actcagattc accaacagaa gccttcatgg tctctttatc 199380 attagactta gaatgccatt cagataacga gtcaagactg tagtgccacg gtggtaacac 199440 tttctcttgt tcaccataga tgttaaagaa aggcgttgtc ttgaacccct tcttagcttt 199500 aaattgcttt tcgcgttctg gcgctttgtc acgcatccac gactcgtacc agtcagtacc 199560 gttaagtttc gaaatgttag acattgaaaa cttagggtct ttatcactag caggatttag 199620 tatttttgcg atagggacat ctagtgggtc gatatcccag aagttgtttc ggaatacgtt 199680 acaaatgaca gtattctgac gttgtgcctc tgctgattct tctgtatcgt agaaggaaga 199740 ccattctaaa cgatagcgat aaaacataca gaaagataaa tactgcatct taaatgtttt 199800 aaatacgtta ccacggccac caaagcccat gatacgagac atgccaccgt tcaagtaggt 199860 ggcaccgtct ttaccacgtt caaagtttcc aagcgcgata tcgaaaagtg gtagtacgtt 199920 ataacgaacg cgcattaatg tgccgttctc tacatcagtt ggggcagcca ttattactcc 199980 tgaatttgta aaggttgttg ctcttcagat gaaaagagtt ttaggtaaaa aaatatatgt 200040 ctgtttctta tgaccgctta attacttatt ctgttcaagg attcttgtta tgaaaaaccc 200100 attcctaccc atccgtcagc gactagttag ttatttaaac cgcggtacaa tcgtacctag 200160 tttaaatgat gtacaacaca acagtggtga gttgattgtt gatttgtcat cagaagacca 200220 agtccgtcta ccagacaaaa gccaccttat ggggttagcg tcatgggttg aacgcgaagg 200280 tttccttttc ttcgatgctt tgcaaatccc acatccggca ggctttaaag ctggcgaaca 200340 aaaactgtac ccgtatgtgc agtcactgaa cacgatgttc aactcattag tgttggtcga 200400 agacatgatt gattacgcca cacagacagt gtccaatctc ttgaatgacc ctgagaagct 200460 tgcatccaaa tccatcaaga gtgatatcaa ttcgttacac aatacttttg accataaaag 200520 tatcacgatg ctggcggata tgtacaaacc attcttcgat aactctaagc agtctgaccg 200580 tgcaagtttt gctgagctgt ttaataacgc tcaagaactt acccgcaccg caaatgaatt 200640 agcgtatttg aatgatcgta tcggtggtgt cgattacgct aagaagatca atgctaagct 200700 agctcgtttg agtgagctat gtatcgagtt caatgaagaa tacccagatc acccagttcg 200760 ctctattctt gtcacacacc tagtatctcc tttagcatac tgggctgagt ttttggcggc 200820 gtatctttac aacgtcaacg tgttgaatgt ttgtttctct gagatagaag agaaactagc 200880 taagatgaaa aaagaaaaat aaaaaaagag gtactcgttt gagtacctct agttcttttt 200940 tttacccggc ttacgctact ttaacgctga ccgcttgtgg acctttctta ccgttctcga 201000 cgccaaagct gaccttctga ccttctttca aagttttgaa gccatcagtt tcgatagcag 201060 agaagtgaac gaacacatct ttaccattgt cttctggtgt gataaaacca aaacctttag 201120 cttcgttggc ttcagctgct gaagagcaaa gtcttgttgc agaggaaatt aactctaaca 201180 caattaagat taaagatttg tccgattctg taaatgaaga tgccgttcaa accaaagacg 201240 ccatcaaaca tcaattagga aatatcaagg aacaaaacaa agtacttgat aagttcaagg 201300 tatagagcac tcttgtggag gggttatgaa catcagtctc attttagcaa catcgagaaa 201360 tcaagtcatt ggtattgggg acaaactacc ttggaaacta ccagttgaca tggcgtggtt 201420 taagaagaat accatgggga agatggtcgt tcaaggaaga aagaccttcg acagtatcgg 201480 cagtccatta cctggacgtg aaaatgtcat cctcactagg gataaaaact tctcttaccc 201540 aatggttaca atatgccgaa ctttcgaagc agcgatgtca ttgatagaaa cacatcaagt 201600 tatcaacccg gatgcagaag tgatgattat tggcggtgct gagatatact ctctcttcga 201660 gcctgtggcg aacaaaatct acatgactag tgtcgatatc gatatacacg ataaagacgc 201720 tgtatttgcc cctgtcttcg atccagagcc atgggagatg gtttacgaag aagcatgggt 201780 gcaggataaa aagaatcctc actctggaac gttttatatc tttgaacgta aataagataa 201840 cagtcgttgg cttcggtcga cgactgtact ttatttttta ccactttgaa ttttattata 201900 gaggtggtga cgaaatgaaa gaatacgtta tcttagaatt agaactatat cgattcgtcg 201960 gtatggaatt aacggggata gaaagattta aactaacccc gagaaaggat aaaatggtta 202020 tccttggtcg taacggcagt ggtaaaagcc gtttactatc tgccttatta gggcactctt 202080 taaataaact tgacttgatg gaaggtggct tttggaaaca aagggcttta atcgatgggg 202140 tcgagtatac gtttaaacag tacagacacg gcaaaggctt acggtgtgat atttactgcg 202200 gagacaaaga aatattgtcc ggggctaacc caactgtcta caatgacaag ataactgcat 202260 tagtcggata cgacaagaaa acacgtgagc ttttaggtgg gctagttaag ctgacaagaa 202320 tgtcaacacc tgaacggaag cattggttta gtcagttagc aaccagtgac ctatcaacgg 202380 cgcttaagta ttacaagtac ctaaaggaaa ctctacgtga cacaatcggt ggtattaagg 202440 taacagaaag atacgtagct gaccttaaac cgatggtcat ggagaccgaa gaagaataca 202500 aagacttatg cacgcgtgtc ggcgaactag aaaccgatta tcacattgtt gcagatcaat 202560 gggtcaagta ttcaaaggta gaatatgtta atgtagatga gttattggct gaggcggata 202620 aatgggctac taaatcacgc gggattaaca tcaatggttt agaaagctac gattactata 202680 ctcagttgat ttctgagctc agtgctgaac tgaagcaact agagaccaat attttaccgc 202740 ggtacaaaaa agaaatcaat gaagtcgata agcaattaag tgaacttcgt tactactcca 202800 atgatacaac taagttaaaa cttctgatag atagtcaaga agataagttg aaaaggcttg 202860 tatttgaaga aaactatttc gacggtgcct tggacgagta cagtcttagt gttctcgaat 202920 cactattaga gaaactcgac acttacgaaa aagaactcaa cgatttagtt attgagcaaa 202980 tctccacaga taaactcaaa gtattgaatg agaaacttga cgctaaaaaa cttgagcatc 203040 aaaacaaact catcgagatg aacaaagctt cagcattcat ccatgacatg acagctatga 203100 ttagtaagca tagtcatgcc aacgaagaag aatgtccgga gtgtaatcat cgtttcaaac 203160 cgggatttaa agcatttgat ttagaggcat caaaacgaca agttaaaaat gcctcaatta 203220 aagaagaagc gctaaaaggg gaaatcgcac agatatgttc agagattgag tttctaacca 203280 atgctgtaca aagaaccatg cgtttaatgg actacgtaca acgtctatat gctgttaatg 203340 gtttggctcc agtcatcggt gcaatgttgg aagatggtgg gatcaatgcc aacacgacgc 203400 cgtataagtg gtttaaagaa tatcgggtgg ggttaaataa aaccatccgt aaactccgta 203460 tagaagcaga gttagataaa ctgaataaag aatacgctgt agcgatggct gtatcaggaa 203520 aggatgttgg gttacttgaa tccagattgg aagagatgac taacaacgtt actaagacac 203580 agttgaaaat cgataagtta cgttctgaaa taactttggt gcaaaaccgt caacgtgaag 203640 cgcaggatgc tgagtacgct gagaccaaac ttgattcact tttaaagata atcgagaatt 203700 cgtctgagaa gcaagcaagt tataactttg ccaagtattt ggaaaaagaa aaagacgagt 203760 tatggtcttt actcagcact tcgaagagca gattgcagac attcgaagag acgagaaaag 203820 aattaaaata taacgaggag aaactagctc aactcaaaga aagaaaaacg gttaacgacg 203880 aactggttaa agcaatgtct ccaacagatg ggctattagc cgagtacttg tataagagca 203940 tctttgctat agccgattcg atgagtttgt tcatcgaaaa catcttcgag tacccgttag 204000 tagtcaaacc ttgtgatgta gacgaaggtg aacttgacta ccaattcccg atggtcgaag 204060 gtgagtctgg tgttacgagg gcagatatta gtcttggctc cgacgcgcaa caggagatta 204120 taaacgctac ctttgtgatg tcggcgatga aagctctgca cttacaacat catcctgtac 204180 tattcgatga acctggtcga gctcttgacc ctgggcataa agttagatac gcagactttt 204240 tatctgagta ttttaacagc gacatggtta gtcaggcctt tgtggtttca cataactcgg 204300 aaatatacac ccgcttcggt aatgttgatt tcatcgttat caatcctgat ggtgtagacc 204360 tcccagacac ttacaacgaa tgtgtggaga tacaatatgg ataatgttat cgagcaccca 204420 tcatcaaatc tacaacatct tattattgtt gctcttgggc aagagattaa taagatgtta 204480 gaagatacaa actaccccta ccaaaaagta aagaacgtgg ataacgttct cgtttttaac 204540 aaagaaggaa atgaacaatg cgtgaacaaa ttgtagaacg tctgaataaa gtatttgctg 204600 atctgaacat cgacctcaca ggtgtaacag atgagagcga cctaagtaat gatttgggtc 204660 tagactccct cgacaacgtg gagttaatca tgggtgtcga agaagagttt ggtatcgaaa 204720 tccctgacga agatagtgtg aatatcacta cttacggtca agttgtgaag tacatcgaag 204780 acaacttgta attcttctct gagggtccag gttttggacc ctcgtcttta tttaaaatga 204840 gcttatggaa gttataaaag tcgctaaatc gagaataaac tcgccatccg ttggtttccc 204900 agtggagata accgtggttg aaattatacc cgaacccacc cctgaggaaa agaagggtat 204960 gcataaggtc ggtaaacatt ataagaagtg gtggaataag gacaggtatt aatgtttggt 205020 ttttttaaag ttatcttaaa acgattgtat tgtttttata aacacaaagg tgatcatcac 205080 tggtcttatg cctaccaagt aaggcaatgg agaaaggggc gtaaacgagg aaagagcacc 205140 catcacagat atgaatataa gttaacatgt gagtgttgtg gaaaagaatc caagtggtta 205200 cgttggaaaa cctttgacga tgtcttttac aaaagcagac atcgtgctct tggaatctac 205260 gaggaaagtt aatttagtta tatgttatat tgatggtgct ttatgctaaa tgtagttgac 205320 gaggagacca tccacggtga tttgttcaaa gctaaagaag atgctttagt agtgacagtt 205380 aatattgtcg gtgccatggg taaagggata gcattgtcct gcaaacaaaa atatccaaca 205440 gtgtataaaa aatacaaaaa ggattgtgat gctggtttgt ttgattacaa caaaatcggt 205500 ttggtaaggg aggataaagc aataatactc ttcccaacca agaaggagtt ttggagggct 205560 gctgacccta aacacatcat ctatctttgt gggagattac cattagcttg caaggcgtgg 205620 ggtattactt ctatagccat accgccgcta ggtatggtta atgggtggtt aaaagaaaag 205680 gaaatagtag gtatagttaa tgccctaaag gagggttttg aagacacaga aataaaagca 205740 actttatact tacctagtaa tcttttagaa ttactatgag tattttcaca ttaatcaaga 205800 agttacaatt gaggaatctt aaaatgaata tcgacgctat gaagaaagca gctaagtttg 205860 ggttggactt tggaattaaa atcttcggtc tactcgttct ttttctaatc actatgtttc 205920 aggctaatgc ctatgccaac actaattgga ataaagtgaa agatgacatt agtctagcgg 205980 cttatttaac tgactttcca gctgaagagt tagcagctgt ggcttttgtg gagtcaagtt 206040 tcagagtgaa ggcgaaatcg cctggtagta gcgcaagtgg cttaacgcaa atcacctcgg 206100 ctacttggga ttacctattg gaaaagtacg ggccggattt caatattcga aagggcactt 206160 ccccatttga cccaagggca aactccatta tggcagcaat gtacctgact gagataaagg 206220 acattatgtc ataccgactt aagcgagaaa cgaccttaat agaaacctac cttgggtata 206280 aattctcacc ttaccgcgca gtcagaatgt tacaatccaa tccgagtaca ccacttttgg 206340 aattttaccc tgaagccgcc gaaagaaacg aagcagtcta ctaccacaaa gatggtagct 206400 taaagacaat cgccgacgtt aagttaatgt ttaagaagcg tctaggtttt gctaagaaaa 206460 catacgggac ctcagctatc gctggtgtta ccgaactgaa gcattttgaa ttcatgccat 206520 ttcaatacgc catggaaaag ggtgtggtgg attgcatacc tgaaggagag atggatgagg 206580 aaactttgtt tagcaaaatt aaacgtaagg ctctggcaac tctaagtaat tccgtggaac 206640 ctattaatga tttaattgct tataacccta agccaacctc gggtcgtgaa tacaacgggt 206700 ttttaatttg atgaaattgt accgtgcaag aatacagcat tggagggaag tggataagat 206760 ggggttgcgt cttgttgacg tcacagtgaa gaccggacta aaacaatttg caccgacgtg 206820 ggatgctttg aaacaattca aagattctaa aagaactgtc gacgacattg ccgtgtacga 206880 tgtgctctat atggagaaga tgaatgagct ttggcgtgta gcaccagaag aattcgacaa 206940 attaactaag gttgatactc tggtattagg ttgttattgt gatcaagaaa accacgatta 207000 ctgtcacgta gattcgttaa tttactgtat agaaaaaata tgtaaggata aaaagatacc 207060 ctaccaatat atgggggtca ttaaaaaata aaagagtacc ctcgtaatga gggtactttc 207120 tttttttatt tatgggtttt ggctttcttc tttctgaata atgactgcta ccaaagcttc 207180 attttgctgt tgtagtttgt ctatttgctc ttcaagattt ttgattctaa catccttcgg 207240 gatgtagttg gtaatagcca gtcggcgcgc acgctcaagg tcagcttgtt gctgtgccgt 207300 caaatcattt tcaaataaat gatttgcttc gtagacatta gcatcgacac ctagtgttgc 207360 tttggcatgg tcagcgagct cggtttttaa agtactgata tcagtaccta atggcaataa 207420 cccaatctct aaagcgatga ttttattttc ataccctctg ttcttaaatc ccggatagtt 207480 aaggatgtaa gttgatggta cgtaaacagg taattcaccg cccgctttaa gagttacaat 207540 cgcagcctct aattcaacat cgcgtttgta ctcgtcttcc gtcaactgca acggttcgta 207600 gtattcagaa aagacctttt tacctagacg cgtcaattca tcaaagctac gaacctcttc 207660 gcaaacataa accaaacccg cttctaattt gaaaggttcg agtaactcga atagccccgt 207720 agcattaaca ggtggcaata gactcctgac tgtcattcaa ttatccttca atgttctcct 207780 gttgagtcgg gtgcatcatc actcggaatt caacgtttaa atattcgaac gcataaaact 207840 tgattttgtt gatttcaaca atagagaagt tgtgatccac tacgttgaaa gaatacaagc 207900 cttctgcgta acccatgcat tcaattagtt ttcgtaggaa ggtcgcagtc tctagacgca 207960 gccgtgaagt ctcatttgac ttaggtggca tgattgggta atctgggaat aattcgaaca 208020 gagtcttttt gccatctggg ttatcagcac ccgccactgc tgccgaagaa agcgacttgt 208080 agtggatagg tacaaaggcc aaataacgac catcgcgatt atttattcca tcagaaccta 208140 gctcttccac ggtttcgaag aaccagttgc tcttctcgac aaatttttca tatgggacta 208200 gtggtgaata agaagcacct tcgttagttt cattcagccc agttgacaat tcccaaaatg 208260 gtaggaaggt aaactcagtt gatgtgaaaa tttcagggaa tactttgatc caatcaccgc 208320 gaccataagc gctattggcc aagatataat cttgtaaagc acgtttaata cgtgttgggt 208380 tagcgcccgc agcaccatac acaatgactg accatgtcgt tgggtgtgta ctttctggat 208440 cttcacggtc atgccacgtg taggtgtaag aaatcaattg cgtatatgga acattgtccg 208500 ctagcaactt tactttttcg tggtgttttg gaatggtgaa atcagctagc gcctctaaca 208560 cggaaggttt agtttgttgg aacacatcga tgttatcgat agggcttaca ggtacaatcg 208620 taaacccagt gtattgatat tcgaaagtgt cattggcaaa ccaaactgta attttgttct 208680 cttcggagtt ttcaagtatg aaactaatcc aagtagggaa ccaactaccg cgctcattaa 208740 ccattgtgcc aactgtcaaa tttcgaatct ttgcagagaa ctcgtttgtg attaatccac 208800 gagcagcttc ctctgactca ttaaggctat cgcctattgc agattcaaaa ataaattgac 208860 aaaccaagct gatagtgtta atgtgttcga taggcggttc tacgtccaac tcatcacgag 208920 ttgaatcaaa caccactaat tcagtatccg tagacttacc acggtagtag cgtttatcct 208980 tagtataact gattgactct tgagacaatt caccaacact agagataacg ccagcttggt 209040 tgttagaaaa gctactgatt ttacaaaaac catttaatga aaacataata aaaacactcc 209100 aagtgttgat aaaactgtga ggttaaataa tgtcagaaaa gctaaaggct ctattcacca 209160 cgattaacga gggttacacc tggttaacag aaggtagcac aaatggtgca aagacactat 209220 ctaaaattct atttgcattt accatcgtcc ttggtcttgt tacatggact attgcagaac 209280 gttactttgt cctactcgac gatgtcaaag taattgtcaa aacaaataat gacaagcaaa 209340 tagaaatcga caaattgaaa ttcgaaagag atcaatttgc tatcaaggcg gaaggcttaa 209400 gtcaaacatt aaacgattta atttccaagc accctactat tatagagaag gaggaagtta 209460 aagagccgca aaaagtgacc gttcctacat atgaagaagc gaaggagacg gctaagccga 209520 ccacaaagag agatgatatg caacggaggc gtcgtttaat agagataatt aatggctaag 209580 ggtatttatg ttgttaaaga aaattgtggc aatagtcact gcttttggag tgggcgggtg 209640 tagcgcacta ctccatccac ctccgtctga tgtggggaag cattctccta caccatctac 209700 ttcggttgaa caaccgatac gcactgcata caaaccaccg ttgagtgccg tgactttacc 209760 accagatatt gcgacatacc agaacatcgg agatgacgtg attgttctta agaactacgc 209820 taccgatctt aactggtaca tgttctatct attcagctac acacatgtga ttaaccaatt 209880 cgctatacag cgaggttggg agccacctaa aacggcaccg ctgtgtaaaa catttgcttg 209940 gccaaagcaa atggatgtcc ccttcttcga atacaaagag ggtatgtcgc tggaggactt 210000 ggatgttgag ttgactttgt ttatatctga agcgaaagct cgttaccaag agcaacagaa 210060 actatttgac gaggcggaga tgtggcagcg tcgtttgtgc atgtattaat aaccttcctt 210120 gtttgacaga gtgtaattac ttcggtagtt acctctgtct ttttttcttt ttttactgtg 210180 tcggtctttt atctgacaga tttgaaaatg atttcttgga gaacacgatg tcagaactat 210240 ttaacaagcc cactatccca tccacagtta cggggattga tttagaaaca aagggtacaa 210300 agctcaacgc tttcattctt gccctgggta gtgtcacatt cgatgtgaaa aaatatcagt 210360 tagtcgagtg ttctcgtttg gaactggacc cagaagacaa agaagccaaa gagttgttta 210420 cggaagatgc agataccctt cgttggtggg aagagtttga taaacatccg tggtcacctt 210480 ctgagttagc aaaaaagatt gcctggggtg ggactactcc acatcgcgaa ggtatcactt 210540 tctttgcaaa gatactggaa caactcaata aaagaaatag tatctttact gcacgtggtc 210600 cagagttcga catgcgcgtt ctcgaggtga gttgtgtgcg ttacggcatc aatcacaatc 210660 tacgttttag taactttgat tcagaccgca cagcggaacg tatgttaaaa gctcttggtt 210720 gttctccgat tagtgaaaat gaactagaga agtacattcg ttgtacggat gctaatggtc 210780 cgctacactc agcacactac gatgcagcca aagaaggcta tcgtacaatg cgagcatatt 210840 ggttagtggc tatagctggt gcctatggac tagacacatt gaaagaagcg gttgcacgtt 210900 tggatgaagg gacttttgac cctgaggtct atggggagat ttgttttgag taaaatcaat 210960 tttgaaactg ctgtcgttta taccgacggt agttctatcg atggaaagca tcgacacgat 211020 actggcagcg gtagcggtat tcacggatac tgttacgata tacctccaac agaacaagcc 211080 aaactaatct tcgaaagaaa tggtgagaag tctttggagt gtcgcggtgt tttaactgaa 211140 gaagttccag aggcttttgg tgatatcgag tatcttcaaa taccaaaaaa tcaatattca 211200 caaaaaattg tttcggtaga agaactcgat ttaactcgcg tagaatgctc acacccaatc 211260 aaaggtggaa cgtcacaagt aggtgagttg ctcgcattca tcgacttgtt tgaaacggca 211320 ccattctctg ccaaagttta ccacatccac accgactcaa gttacctgaa agatggttac 211380 acccaatgga tggataactg gaaacgaaaa ggttgggtga atagttctgg ggctgttaag 211440 aacaaagaac tttggattcg tatcgatgcg attaaacaac gtgagagcaa aggcgagttt 211500 aaaataaact ggcataaaat taaagggcac agtgatcgtt ttggaaatga gtctgcggac 211560 atgttggcag gcaaagcttc tggaaaagct atcaacatgg tcttaaacga tgaacatcgt 211620 gatgcgtata tccccgaatg ggatatcgga ccttacgtag ttggtgacga tactcttatt 211680 tacgaaacta aagaagagaa acgtaacaaa gcgaaagaag ctaaaagcga caaaaagaat 211740 gcatcaaagt cagacaagcc aaaaaaggta aaagacgaag agaaattcat ccccaaactc 211800 ttgcgtctga agtatcatta catgatgtcg aatggcgaag aaacagtcgt gaatgtcggg 211860 ggagaagagc tgtaccgtta ctttggtggg gatcatgcta agatgaaaga cgatcgtctt 211920 cttctcggca aagcccaacc tgacaacatg caggttctga cttttgtgaa agaccctgtg 211980 cgtatcttct ccgatatagc gacagtcgta tctgaccata tgtggaaaga tgtaccgatg 212040 atgtatcgtt ctgacctcgt tcttttgatg aatggtactt tcatgaatca agagaaattc 212100 aatcgacgtt tgctagacga ctacgatttc tcaaccttcc cgtacaatcg ttcattcaac 212160 gaattactat tcgatgagaa aaactgggta tcggttgctt gtaggccacc gggtctaagt 212220 tatcgtgcaa tggatgtggc tgactctatc acgaactggt atgtggagtt tgttgataat 212280 gatcgtaaga gtacagacac tgtatcggta ctagacatca cttctaagct ttacgatggc 212340 aagaagatga cagattggta tcgtgtcatc gacaagagcg ttcgtgttca aatgcctgtt 212400 ccaggcgacg aagagcgtaa agtggacttg atcctcacac ggaatatctc cttccctgac 212460 cgtaaccatt ttaacaaatt ggttaaagac gacccaaggg tttacattgt tgctcgtaag 212520 ttatcggata atggtttccg ttacttcgtt gttctggaaa ctaaggtcgg taatcaggta 212580 gtgtgttctt accatagttc tcttcgaatc cacgaataaa gagttatatg ttatcgtagt 212640 gatacaataa cagagggttc tttaaatggc tgataaatta cgtgttaaaa taccacgtat 212700 aatggttgat gctattggta agataaccga agatgcgtac tttaaattag actatcaaat 212760 gacacttgat agtctaaaaa tacaccctga ttcagttgac cgtgatatgc tgagagatga 212820 cttatctgaa atcatgcata acgtcatcgg aaacatgtta gctatcttgt ttgaggattt 212880 ggctctcctc atgctagaaa cgcaaacaga gtatggtaaa aggttcatcg attggaaaga 212940 tttaccaacg gctaataaat taaatcaact aacaatagat gaggatggtg gatatctaga 213000 cgccaaactc ggggaggtcg aagctgaatc tgccgacacc tctggcgaat atttaacaca 213060 tcattctaac atcctgggga caatgggtca cacttgccgt gaaatctatt atagttcttt 213120 ttattccaaa gaagacgata tggaatttcg taaaggggtt gctgatttag gcaatcacct 213180 tttagaccac ggtgccgtgt ctttcgacta cgattcgttg attaccgaaa tcattgatag 213240 agagataaat agtttccgtt cattagaatt gagaacttac gaagttgatg attttacact 213300 ggtatcggaa ttcaccccta aaattaacgg tgggtggatt gataatgtca atgataccga 213360 agtcgaatgg gggttgatag aacgtgagct agatgcagtt gcaagaactt ctggtgatat 213420 gtttgttctt gtcaatcatc acgatatcta cattggtgac catgtagata aaataaacga 213480 cttacctgtc gttgagtcta tcggtataat ggaggctaac taatggctgt aatccgaaat 213540 aataaactta ttaagggtga agctagagat atcctaatta agttaatcga agactgcgtt 213600 cttgaaatta tcgaggtgca tccgcgcatc gatgaagctg acctacaaga cactgtaggt 213660 cgggtaatat gggagctcat ctgggcttct gttgatggaa gagcagtgga ccgaaagtac 213720 atagagcgtc aggcaatgcc taagcgttcc agtgcgattt ggccgcttgt tctaaactcc 213780 atagaaatca ctgcaagaga gtttgtaaat catccagacg tccaggctga cctagatgac 213840 tactacgaag cgatggagca gattaaagat gactatggta tgtaattaaa agtaatattg 213900 gaaagagaaa taaattatgg caaatgtaat taaaggcaca gtgaagtggt tcaacgaagc 213960 taaaggtttt 213970

Claims (7)

  1. 비브리오 앵길라룸 균을 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는, 자연으로부터 분리된 시포비리대 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP).
  2. 제1항의 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP)을 유효성분으로 포함하는, 비브리오 앵길라룸 균에 의해 유발되는 질환 예방용 또는 치료용 조성물.
  3. 제2항에 있어서, 상기 조성물은 약욕제, 또는 사료첨가제 형태로 사용되는 것을 특징으로 하는, 비브리오 앵길라룸 균에 의해 유발되는 질환 예방용 또는 치료용 조성물.
  4. 제2항에 의한 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP)을 유효성분으로 포함하는 조성물에 사람을 제외한 동물을 담그는 처치를 실시하는 단계를 포함하는, 비브리오 앵길라룸 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
  5. 제4항에 있어서, 상기 조성물이 약욕제 형태인 것을 특징으로 하는, 비브리오 앵길라룸 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
  6. 제2항에 의한 박테리오파지 Vib-ANP-1(수탁번호 KCTC 13075BP)을 유효성분으로 포함하는 조성물을 사람을 제외한 동물에 투여하는 단계를 포함하는, 비브리오 앵길라룸 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
  7. 제6항에 있어서, 상기 조성물이 사료첨가제 형태인 것을 특징으로 하는, 비브리오 앵길라룸 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
KR1020160112908A 2016-09-02 2016-09-02 신규한 비브리오 앵길라룸 박테리오파지 Ｖｉｂ-ＡＮＰ-1 및 이의 비브리오 앵길라룸 균 증식 억제 용도 KR101816511B1 (ko)

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PCT/KR2017/009076 WO2018043972A2 (ko) 2016-09-02 2017-08-21 신규한 비브리오 앵길라룸 박테리오파지 Ｖｉｂ-ＡＮＰ-1 및 이의 비브리오 앵길라룸 균 증식 억제 용도
US16/329,931 US11439677B2 (en) 2016-09-02 2017-08-21 Vibrio anguillarum bacteriophage VIB-ANP-1 and use thereof for inhibiting proliferation of Vibrio anguillarum bacteria
CN201780062926.5A CN109890958B (zh) 2016-09-02 2017-08-21 新型鳗弧菌噬菌体vib-anp-1及其用于抑制鳗弧菌细菌增殖的用途

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US20140105866A1 (en) 2012-10-17 2014-04-17 Universidad De Chile Bacteriophages useful for the prophylaxis and therapy of vibrio anguillarum

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KR101267616B1 (ko) 2012-01-09 2013-05-31 씨제이제일제당 (주) 신규 분리된 박테리오파지 및 이를 포함하는 항균 조성물

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WO2018043972A2 (ko) 2018-03-08
CN109890958A (zh) 2019-06-14

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