KR101859974B1 - 신규한 에로모나스 하이드로필라 박테리오파지 Aer-HYP-2 및 이의 에로모나스 하이드로필라 균 증식 억제 용도 - Google Patents

신규한 에로모나스 하이드로필라 박테리오파지 Aer-HYP-2 및 이의 에로모나스 하이드로필라 균 증식 억제 용도 Download PDF

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KR101859974B1
KR101859974B1 KR1020170078391A KR20170078391A KR101859974B1 KR 101859974 B1 KR101859974 B1 KR 101859974B1 KR 1020170078391 A KR1020170078391 A KR 1020170078391A KR 20170078391 A KR20170078391 A KR 20170078391A KR 101859974 B1 KR101859974 B1 KR 101859974B1
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윤성준
전수연
권안성
송현민
강상현
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Abstract

본 발명은 에로모나스 하이드로필라 균을 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 미오비리대 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP), 및 이를 유효성분으로 포함하는 조성물을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법에 관한 것이다.

Description

신규한 에로모나스 하이드로필라 박테리오파지 Aer-HYP-2 및 이의 에로모나스 하이드로필라 균 증식 억제 용도{Novel Aeromonas hydrophila bacteriophage Aer-HYP-2 and its use for preventing proliferation of Aeromonas hydrophila}
본 발명은 에로모나스 하이드로필라 균에 감염하여 에로모나스 하이드로필라 균을 사멸시킬 수 있는 자연으로부터 분리한 박테리오파지 및 이를 유효성분으로 포함한 조성물을 이용한 에로모나스 하이드로필라 균에 의해서 유발되는 질환을 예방 또는 치료하는 방법에 관한 것으로, 더욱 상세하게는 에로모나스 하이드로필라 균을 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 미오비리대 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP), 및 상기 박테리오파지를 유효성분으로 포함하는 조성물을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환의 예방 또는 치료하는 방법에 관한 것이다.
에로모나스 속(Genus)에 속하는 에로모나스 하이드로필라(Aeromonas hydrophila) 균은 운동성 그람음성 간균이며, 하천수나 담수어에 널리 분포하는 수계 상재균으로서 주로 메기, 무지개 송어와 같은 담수 어류 또는 비단 잉어와 같은 관상용 어류에 심각한 질병을 야기하는 원인균으로 잘 알려져 있다. 에로모나스 하이드로필라 균의 항원형(Serotype)으로는 열 안정성 균체항원(Thermo-stable, O antigen), 열 불안정 협막항원(Thermo-labile, K antigen), 및 편모항원(Flagella, H antigen)이 있는 것으로 알려져 있으며, 현재까지 알려진 병원성 에로모나스 하이드로필라 균의 대부분은 열 안정성 균체항원을 갖고 있는 것으로 알려져 있다.
에로모나스 하이드로필라 균은 다양한 어류에서 운동성 에로모나스 패혈증(Motile Aeromonas Septicemia)이나 피부 궤양(Ulcer) 등과 같은 에로모나스 질병(Aeromonas diseases)을 유발하기도 하며, 정도가 심각한 경우에는 집단 폐사를 야기 시킬 수 있어서 담수 어류의 양식 산업에서 중요한 경제적 손실의 원인이 되고 있다. 따라서 에로모나스 하이드로필라 균 감염을 예방하고 나아가 감염 처치에까지 활용될 수 있는 방안의 개발이 절실한 실정이다.
에로모나스 하이드로필라 균에 의해 유발되는 질환의 예방이나 치료 목적으로 다양한 항생제들이 사용되어 왔으나 최근 이들 항생제들에 대한 내성균의 발생이 증가함에 따라 항생제 외의 다른 방안의 확보가 시급한 실정이다.
최근 세균성 감염질환의 대처 방안으로 박테리오파지(Bacteriophage)의 활용이 크게 주목을 받고 있다. 특히 항생제 내성균에 대한 우수한 항균력 때문에 더욱 큰 관심을 받고 있다. 박테리오파지는 세균에 감염하는 아주 작은 미생물로서 보통 파지(Phage)라고 줄여서 부르기도 한다. 박테리오파지는 세균에 감염(Infection)한 후에 세균의 세포 내부에서 증식을 하고, 증식 후 자손 박테리오파지들이 세균 밖으로 나올 때 숙주인 세균의 세포벽을 파괴하는 방식으로 세균을 사멸시키는 능력을 갖고 있다. 박테리오파지의 세균 감염 방식은 매우 특이성이 높아서 특정 세균에 감염할 수 있는 박테리오파지의 종류는 일부로 한정된다. 즉, 특정 박테리오파지는 특정 범주의 세균에만 감염할 수 있고 이로 인하여 특정 박테리오파지는 특정 세균에 대해서만 항균효과를 제공할 수 있다. 이러한 박테리오파지의 세균 특이성으로 인하여 박테리오파지는 대상으로 하는 세균에 대해서만 항균효과를 제공하고 환경이나 동물 내의 상재균들에는 영향을 초래하지 않는다. 통상적으로 세균 처치에 널리 활용되던 기존의 항생제들은 여러 종류의 세균들에 대하여 동시에 영향을 끼쳤다. 이로 인하여 환경오염이나 동물의 정상 세균총 교란 등의 문제를 초래하였다. 이와는 달리 박테리오파지는 특정 세균에 대해서만 작동하므로 박테리오파지 사용에 의해서 체내 정상균총 교란 등이 발생하지 않는다. 따라서 박테리오파지 사용이 항생제 사용에 비교하여 매우 안전하다고 할 수 있고, 그 만큼 사용에 의한 부작용 초래 가능성이 상대적으로 크게 낮다.
박테리오파지는 1915년 영국의 세균학자 Twort가 포도상구균(Micrococcus) 집락이 어떤 것에 의해 투명하게 녹는 현상에 대한 연구를 수행하면서 발견되었다. 또한, 1917년에는 프랑스의 세균학자 d'Herelle이 이질환자 변의 여과액 중에 적리균(Shigella dysenteriae)을 녹이는 작용을 가진 것이 있다는 것을 발견하고 이에 대한 연구를 통해 독립적으로 박테리오파지를 발견하였으며, 세균을 잡아먹는다는 뜻에서 박테리오파지라고 명명하였다. 이후 이질균, 장티푸스균, 콜레라균 등 여러 병원성 세균에 대한 박테리오파지가 계속적으로 발견되었다.
세균을 사멸시킬 수 있는 특별한 능력으로 인하여 박테리오파지는 발견 이후부터 세균 감염에 대응하는 효과적 방안으로 기대를 모았으며 관련하여 많은 연구들이 있었다. 그러나 Fleming에 의해 페니실린이 발견된 이후, 항생제의 보급이 일반화되면서 박테리오파지에 대한 연구는 일부 동유럽 국가들 및 구소련에 한정되어서만 명맥이 유지되었다. 그런데 2000년 이후에 항생제 내성균의 발생 증가로 인하여 기존 항생제의 한계성이 나타나고, 기존 항생제의 대체 물질로의 개발 가능성이 부각되면서 다시 박테리오파지가 항-세균제로 주목을 받고 있다.
앞에서 설명했듯이 박테리오파지는 세균에 대한 특이성이 매우 높다. 이러한 박테리오파지의 세균에 대한 높은 특이성으로 인하여 박테리오파지는 동일 종(Species)에 속하는 세균들이라 할지라도 그 일부 주(Strain)에 대해서만 항균효과를 발휘하는 경우가 많다. 또한 대상 세균 주에 따라 발휘되는 박테리오파지의 항균력 세기 자체도 다를 수 있다. 이러한 이유로 특정 종류의 세균에 대하여 효과적 제어법을 확보하려면 다양한 종류의 유용 박테리오파지들의 확보가 필요하다. 에로모나스 하이드로필라 균에 대응하여 효과적인 박테리오파지 활용법을 개발하기 위해서도 당연히 에로모나스 하이드로필라 균에 대하여 항균효과를 제공할 수 있는 여러 종류의 다양한 박테리오파지들의 확보가 필요하고, 더 나아가 확보한 다양한 유용 박테리오파지들 중에서 항균력의 세기나 항균범위 측면에서 비교우위에 있는 박테리오파지의 선발 활용도 필요하다.
이에, 본 발명자들은 에로모나스 하이드로필라 균을 사멸시킬 수 있는 자연으로부터 분리된 박테리오파지를 이용하여 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 데에 활용될 수 있는 조성물을 개발하고, 또 이 조성물을 이용하여 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법을 개발하고자 노력한 끝에, 이에 적합한 박테리오파지를 자연으로부터 분리하고, 이 분리된 박테리오파지를 타 박테리오파지와 구별하여 특정 지을 수 있도록 유전체(Genome)의 서열 정보를 확보한 후에 상기 박테리오파지를 유효성분으로 한 조성물을 개발한 다음에 이 조성물이 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 목적으로 효과적으로 활용될 수 있음을 확인함으로써 본 발명을 완성하였다.
따라서 본 발명의 목적은 에로모나스 하이드로필라 균을 특이적으로 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 미오비리대(Myoviridae) 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP)를 제공하는 것이다.
또한, 본 발명의 또 다른 목적은 에로모나스 하이드로필라 균에 감염하여 에로모나스 하이드로필라 균을 사멸시킬 수 있는 분리 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP)를 유효성분으로 포함하는 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 목적으로 활용 가능한 조성물을 제공하는 것이다.
본 발명의 또 다른 목적은 에로모나스 하이드로필라 균에 감염하여 에로모나스 하이드로필라 균을 사멸시킬 수 있는 분리 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP)를 유효성분으로 포함하는 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 목적으로 활용 가능한 조성물을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법을 제공하는 것이다.
본 발명의 또 다른 목적은 상기 조성물들을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 목적으로 사용되는 약욕제를 제공하는 것이다.
본 발명의 또 다른 목적은 상기 조성물들을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환의 예방 또는 치료를 통한 사양 효과 제공 목적의 사료첨가제를 제공하는 것이다.
본 발명은 에로모나스 하이드로필라 균을 특이적으로 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리한 미오비리대 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP), 및 이를 유효성분으로 포함하는 조성물을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법을 제공한다.
박테리오파지 Aer-HYP-2는 본 발명자들에 의해 분리된 후에 2017년 5월 10일자로 한국생명공학연구원 생물자원센터에 기탁되었다(수탁번호 KCTC 13258BP).
또한, 본 발명은 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 데에 활용될 수 있는 박테리오파지 Aer-HYP-2를 유효성분으로 포함하는 약욕제 및 사료첨가제를 제공한다.
본 발명의 조성물에 포함되는 박테리오파지 Aer-HYP-2는 에로모나스 하이드로필라 균을 효과적으로 사멸시키므로 에로모나스 하이드로필라 균에 의해 유발되는 질환의 예방(감염 방지)이나 치료(감염 처치)에 효과를 나타낸다. 따라서 본 발명의 조성물은 에로모나스 하이드로필라 균에 의해 유발되는 질환에 대한 예방 또는 치료 목적으로 활용될 수 있다.
본 명세서에서 사용된 “방지” 또는 “예방”이라는 용어는 (ⅰ) 에로모나스 하이드로필라 균의 감염 방지; 및 (ⅱ) 에로모나스 하이드로필라 균 감염에 의한 질병으로의 발전을 억제하는 것을 의미한다.
본 명세서에서 사용된 “처치” 또는 “치료”라는 용어는 (ⅰ) 에로모나스 하이드로필라 균에 의해 유발된 질환의 억제; 및 (ⅱ) 에로모나스 하이드로필라 균에 의해 유발된 질환의 병적상태를 경감시키는 모든 행위를 의미한다.
본 명세서의 “분리”, “분리한” 또는 “분리된”은 자연 상태로부터 여러 실험 기법을 활용하여 박테리오파지를 분리하는 것과 타 박테리오파지와 구별하여 본 발명의 박테리오파지를 특정 지을 수 있는 특징을 확보하는 일을 지칭하며, 이에 더하여 생물공학기술로 본 발명의 박테리오파지를 산업적으로 활용할 수 있게끔 증식시키는 것도 포함한다.
본 발명의 조성물에 포함되는 약제학적으로 허용되는 담체는 제제 시에 통상적으로 이용되는 것으로서, 락토오스, 덱스트로오스, 수크로오스, 솔비톨, 만니톨, 전분, 아카시아 고무, 인산칼슘, 알기네이트, 젤라틴, 규산칼슘, 미세결정성 셀룰로오스, 폴리비닐피롤리돈, 셀룰로오스, 물, 시럽, 메틸 셀룰로스, 메틸히드록시벤조에이트, 프로필히드록시벤조에이트, 활석, 스테아르산 마그네슘 및 미네랄 오일 등을 포함하나, 이에 한정되는 것은 아니다. 본 발명의 조성물은 상기 성분들 이외에 윤활제, 습윤제, 감미제, 향미제, 유화제, 현탁제, 보존제 등을 추가로 포함할 수 있다.
본 발명의 조성물에는 박테리오파지 Aer-HYP-2가 유효성분으로 포함된다. 이때 포함되는 박테리오파지 Aer-HYP-2는 1× 101 pfu/㎖ 내지 1× 1030 pfu/㎖ 또는 1× 101 pfu/g 내지 1× 1030 pfu/g로 포함되며, 바람직하게는 1× 104 pfu/㎖ 내지 1× 1015 pfu/㎖ 또는 1× 104 pfu/g 내지 1× 1015 pfu/g로 포함된다.
본 발명의 조성물은 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자가 용이하게 실시할 수 있는 방법에 따라, 약학적으로 허용되는 담체 및/또는 부형제를 이용하여 제제화 됨으로써 단위 용량 형태로 제조되거나 또는 다용량 용기 내에 내입시켜 제조될 수도 있다. 이때 제형은 오일 또는 수성 매질 중의 용액, 현탁액 또는 유화액 형태이거나 엑스제, 분말제, 과립제, 정제 또는 캡슐제 형태일 수도 있으며, 분산제 또는 안정화제를 추가적으로 포함할 수도 있다.
본 발명의 조성물은 활용 방식에 따라, 이에 국한되지 않지만 약욕제 및 사료첨가제로 구현될 수 있다. 이러한 활용 목적에서의 효율성을 높이기 위하여 다른 세균종에 대하여 항균활성을 제공할 수 있는 박테리오파지들이 본 발명의 조성물에 추가될 수 있다. 또한, 에로모나스 하이드로필라 균에 대하여 항균활성을 갖는 다른 종류의 박테리오파지들도 추가될 수 있다. 에로모나스 하이드로필라 균에 대하여 항균활성을 갖는 박테리오파지라 하더라도 항균력의 세기나 항균범위 측면에서 서로 간에 차이가 있으므로 이들의 적절한 조합은 그 효과를 극대화 할 수 있다.
본 발명의 박테리오파지 Aer-HYP-2를 유효성분으로 포함하는 조성물을 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법은 기존의 항생제 등에 기반을 둔 방식에 비하여 에로모나스 하이드로필라 균에 대한 특이성이 매우 높다는 장점을 제공할 수 있다. 이는 다른 유용한 상재균에는 영향을 주지 않으면서도 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 목적으로 사용할 수 있음을 의미하며, 이의 사용에 따른 부작용이 매우 적다는 것을 의미한다. 통상적으로 항생제 등을 사용하면 일반 상재균들도 피해를 함께 입게 되어 결과적으로 동물의 면역력 저하 등을 초래시켜 사용에 따른 다양한 부작용이 나타난다. 한편, 박테리오파지는 항균활성을 발휘할 수 있는 세균종이 같다 하더라도 항균효과 발휘에 있어 항균력의 세기나 항균범위[에로모나스 하이드로필라 균종에 속하는 여러 세균 주(Strain)의 측면에서 개별 세균 주에 대하여 박테리오파지의 항균활성이 발휘되는 범위. 통상적으로 박테리오파지는 같은 세균 종(Species)에 속하는 일부 세균 주(Strain)에 대하여 항균활성을 발휘할 수 있음. 즉, 같은 세균 종에 속한다 하더라도 개별 세균 주에 따라 박테리오파지에 대한 감수성에서 차이가 있을 수 있음] 측면에서 차이가 있으므로 본 발명은 에로모나스 하이드로필라 균에 대한 항균력을 갖는 타 박테리오파지에 비교하여 차별적 항균효과를 제공할 수 있다. 이는 산업현장 활용 시에 그 효과에 있어 큰 차이를 제공한다.
도 1은 박테리오파지 Aer-HYP-2의 전자현미경 사진이다.
도 2는 박테리오파지 Aer-HYP-2의 에로모나스 하이드로필라 균에 대한 사멸능을 보여주는 실험 결과이다. 평판배지의 가운데 선을 기준으로 왼쪽은 박테리오파지 Aer-HYP-2가 포함되지 않은 완충액(Buffer)만을 점적한 것이고, 오른쪽은 박테리오파지 Aer-HYP-2가 포함된 액을 점적한 것이다. 오른쪽에서 관찰되는 투명한 부분은 시험대상 세균이 박테리오파지 Aer-HYP-2의 작용에 의하여 용균되어 결과적으로 형성된 용균반이다.
이하, 실시예에 의거하여 본 발명을 보다 구체적으로 설명하지만, 이들 실시예는 본 발명의 예시일 뿐이며 본 발명의 범위가 이들 실시예에 한정되는 것은 아니다.
실시예 1: 에로모나스 하이드로필라 균을 사멸시킬 수 있는 박테리오파지의 분리
에로모나스 하이드로필라 균을 사멸시킬 수 있는 박테리오파지의 분리에는 자연 환경으로부터 확보된 시료들을 이용하였다. 한편, 박테리오파지 분리에 사용된 에로모나스 하이드로필라 균주들은 본 발명자들에 의해 미리 분리되어 에로모나스 하이드로필라 균으로 동정(Identification)된 것들이다.
박테리오파지 분리 과정을 상세히 설명하면, 에로모나스 하이드로필라 균을 1/1,000 비율로 접종한 TSB(Tryptic Soy Broth) 배지(카제인 다이제스트, 17 g/L; 소이빈 다이제스트, 3 g/L; 덱스트로스, 2.5 g/L; NaCl, 5 g/L; 디포타슘 포스페이트, 2.5 g/L)에 수집된 시료를 함께 첨가한 다음 25℃에서 3-4시간동안 진탕배양 하였다. 배양 후, 8,000 rpm에서 20분간 원심분리하여 상등액을 회수하였다. 회수된 상등액에 에로모나스 하이드로필라 균을 1/1,000 비율로 접종한 다음 25℃에서 3-4시간 동안 또 다시 진탕배양 하였다. 박테리오파지가 시료에 포함되어 있었을 경우에는 박테리오파지의 수(Titer)가 충분히 증가될 수 있도록 이러한 과정을 총 5회 반복 실시하였다. 5회 반복 실시 후에 배양액을 8,000 rpm에서 20분간 원심분리 하였다. 원심분리 후, 회수된 상등액에 대하여 0.45 μm의 필터를 이용하여 여과를 실시해 주었다. 이렇게 하여 얻어진 여과액을 사용한 통상의 점적 실험(Spot assay)을 통하여 에로모나스 하이드로필라 균을 사멸시킬 수 있는 박테리오파지가 있는지를 조사하였다.
상기 점적 실험은 다음과 같이 실시되었다. TSB 배지에 에로모나스 하이드로필라 균을 1/1,000 비율로 접종한 다음 25℃에서 한밤동안 진탕배양 하였다. 이렇게 하여 준비된 에로모나스 하이드로필라 균의 배양액 3 ㎖(OD600이 1.5)을 TSA(Tryptic Soy Agar) 평판배지(카제인 다이제스트, 15 g/L; 소이빈 다이제스트, 5 g/L; NaCl, 5 g/L; 아가, 15 g/L)에 도말(Spreading)하였다. 도말한 평판 배지를 클린벤치(Clean bench)에서 약 30분 정도 방치하여 도말액이 건조되게 하였다. 건조 후 앞에서 준비한 여과액 10 μl를 에로모나스 하이드로필라 균이 도말된 평판 배지 위에 점적하였다. 이를 30분 정도 방치하여 건조시켰다. 건조 후 점적한 평판 배지를 25℃에서 하루 동안 정치 배양한 다음 여과액이 떨어진 위치에 투명환(Clear zone)이 생성되는가를 조사하였다. 투명환이 생성되는 여과액의 경우가 에로모나스 하이드로필라 균을 사멸 시킬 수 있는 박테리오파지가 포함되어 있다고 판단할 수 있다. 이러한 조사를 통하여 에로모나스 하이드로필라 균에 대한 사멸능을 가진 박테리오파지를 포함한 여과액을 확보할 수 있었다.
에로모나스 하이드로필라 균에 대한 사멸능을 가진 박테리오파지의 존재가 확인된 여과액을 이용하여 순수 박테리오파지의 분리를 실시하였다. 순수 박테리오파지의 분리에는 통상의 용균반 분석(Plaque assay)을 이용하였다. 이를 자세히 설명하면, 용균반 분석에서 형성된 용균반 하나를 멸균된 팁을 이용하여 회수한 다음에 이를 에로모나스 하이드로필라 균의 배양액에 첨가해 주어 4-5시간 동안 25℃에서 함께 배양하였다. 배양 후 8,000 rpm에서 20분간 원심분리하여 상등액을 얻었다. 얻어진 상등액에 50분의 1의 부피로 에로모나스 하이드로필라 균의 배양액을 첨가해 준 다음에 다시 25℃에서 4-5시간 동안 배양해 주었다. 박테리오파지의 수를 증가시키기 위하여 이러한 과정을 최소 5회 이상 실시한 다음에 최종적으로 8,000 rpm에서 20분간 원심분리하여 상등액을 얻었다. 얻어진 상등액을 사용하여 다시 용균반 분석을 실시하였다. 통상 순수 박테리오파지의 분리가 상기 과정의 1회만으로는 달성되지 않기 때문에 이때 형성된 용균반을 이용하여 앞 단계를 전체적으로 다시 반복하였다. 이와 같은 과정을 최소 5회 이상 반복 실시하여 순수한 박테리오파지를 포함한 용액을 확보하였다. 통상적으로 순수 박테리오파지의 분리는 형성된 용균반의 크기 및 모양이 모두 유사하게 될 때까지 반복 수행하였다. 그리고 최종적으로는 전자현미경 분석을 통하여 박테리오파지의 순수 분리 여부를 확인하였다. 전자현미경 분석에서 순수 분리가 확인될 때까지 앞에 설명한 과정을 반복하였다. 전자현미경 분석은 통상의 방법에 따라 실시하였다. 이를 간단히 설명하면 다음과 같다. 순수한 박테리오파지를 포함한 용액을 구리 격자(Copper grid)에 묻히고 2% 우라닐 아세테이트(Uranyl acetate)로 역염색법(Negative staining)과 건조를 수행한 후에 투과전자현미경을 통하여 그 형태를 관찰하였다. 순수 분리한 박테리오파지의 전자현미경 사진이 도 1에 제시되어 있다. 형태적 특징으로 판단할 때, 신규 확보된 박테리오파지는 미오비리대(Myoviridae) 박테리오파지에 속함을 확인할 수 있었다.
이런 방식으로 확인된 순수 박테리오파지를 포함한 용액은 다음의 정제 과정을 거쳤다. 순수 박테리오파지를 포함한 용액에 용액 전체 부피의 50분의 1의 부피로 에로모나스 하이드로필라 균의 배양액을 첨가해 준 다음에 다시 4-5시간 동안 배양하였다. 배양 후 8,000 rpm에서 20분간 원심분리하여 상등액을 얻었다. 충분한 수의 박테리오파지가 포함된 액을 얻기 위해 이러한 과정을 총 5회 반복하였다. 최종 원심분리로 얻어진 상등액을 0.45 μm의 필터를 이용하여 여과한 다음에 통상의 폴리에틸렌 글리콜(Polyethylene Glycol; PEG) 침전 과정을 실시하였다. 구체적으로, 여과액 100 ㎖에 10% PEG 8000/0.5 M NaCl이 되게 PEG와 NaCl을 첨가한 다음에 4℃에서 2-3시간 동안 정치한 후, 8,000 rpm에서 30분간 원심분리하여 박테리오파지 침전물을 얻었다. 이렇게 얻어진 박테리오파지 침전물을 완충액(Buffer; 10 mM Tris-HCl, 10 mM MgSO4, 0.1% Gelatin, pH 8.0) 5 ㎖로 부유시켰다. 이를 박테리오파지 부유액 또는 박테리오파지 액이라 지칭한다.
상기 과정을 통하여 정제된 순수 박테리오파지를 확보할 수 있었고, 이 박테리오파지를 박테리오파지 Aer-HYP-2로 명명한 뒤, 2017년 5월 10일자로 한국생명공학연구원 생물자원센터에 기탁하였다(수탁번호 KCTC 13258BP).
실시예 2: 박테리오파지 Aer - HYP -2의 유전체 분리 및 유전체 서열 분석
박테리오파지 Aer-HYP-2의 유전체를 다음과 같이 분리하였다. 유전체 분리에는 실시예 1에서와 같은 방법으로 얻어진 박테리오파지 부유액을 이용하였다. 먼저 부유액에 포함되어 있을 수 있는 에로모나스 하이드로필라 균의 DNA와 RNA를 제거하기 위해, 박테리오파지 부유액 10 ㎖에 DNase I과 RNase A를 각각 200 U씩 첨가한 다음에 37℃에서 30분간 방치하였다. 30분 방치 후에 DNase I과 RNase A의 활성을 제거하기 위해, 0.5 M 에틸렌디아민테트라아세트산(Ethylenediaminetetraacetic acid; EDTA) 500 μl를 첨가한 다음에 다시 10분간 정치시켰다. 그리고 이를 추가로 10분간 65℃에 정치시킨 다음에 박테리오파지 외벽을 와해시키기 위해 proteinase K(20 ㎎/㎖) 100 μl를 첨가한 후에 37℃에서 20분간 반응시켰다. 그 후 10% 도데실 황산 나트륨염(Sodium dodecyl sulfate; SDS) 500 μl를 첨가한 다음에 다시 65℃에서 1시간 동안 반응시켰다. 1시간 반응 후, 이 반응액에 25:24:1의 구성비를 갖는 페놀(Phenol) : 클로로포름(Chloroform) : 이소아밀알코올(Isoamylalcohol)의 혼합액 10 ㎖을 첨가해 준 후 잘 섞어 주었다. 그리고는 이것을 13,000 rpm에서 15분간 원심분리하여 층이 분리되게 한 다음에 분리된 층들 중에서 위층을 취하여 여기에 1.5 부피비의 아이소프로필 알코올(Isopropyl alcohol)을 첨가한 다음에 13,000 rpm에서 10분간 원심분리하여 유전체를 침전시켰다. 침전물을 회수한 후 침전물에 70% 에탄올(Ethanol)을 첨가한 다음에 다시 13,000 rpm에서 10분간 원심분리하여 침전물의 세척을 실시하였다. 세척된 침전물을 회수하고 진공 건조 시킨 다음에 이를 100 μl의 물에 녹였다. 상기 과정을 반복하여 박테리오파지 Aer-HYP-2의 유전체를 다량 확보하였다.
이렇게 얻어진 유전체는 마크로젠에서 illumina Mi-Seq 기기를 이용하여 차세대염기서열 분석(Next generation sequencing analysis)을 수행한 다음 박테리오파지 Aer-HYP-2의 유전체 서열 정보를 확보하였다. 최종적으로 분석된 박테리오파지 Aer-HYP-2 유전체는 236,916 bp의 크기를 가지며, 전체 유전체 서열은 서열번호 1로 제시되어 있다.
확보된 박테리오파지 Aer-HYP-2의 유전체 서열 정보를 기반으로 Web상의 BLAST를 이용하여 기존에 알려진 박테리오파지 유전체 서열과의 상동성(Similarity)을 조사해 보았다. BLAST 조사 결과, 50% 이상의 상동성을 가진 박테리오파지 서열은 확인할 수 없었다.
이러한 사실에 근거하여 박테리오파지 Aer-HYP-2는 기존 보고된 박테리오파지들과는 다른 신규한 박테리오파지라 결론지을 수 있었다. 이러한 사실과 함께 통상적으로 박테리오파지의 종류가 다르면 제공할 수 있는 항균력의 세기 및 항균범위가 다르다는 사실로부터 박테리오파지 Aer-HYP-2는 기존에 보고된 다른 박테리오파지들과는 다른 항균효과를 제공해 줄 수 있다고 판단할 수 있었다.
실시예 3: 박테리오파지 Aer - HYP -2의 에로모나스 하이드로필라 균에 대한 사멸능 조사
분리된 박테리오파지 Aer-HYP-2의 에로모나스 하이드로필라 균에 대한 사멸능을 조사하였다. 사멸능 조사는 실시예 1에서 제시한 점적 실험을 통하여 투명환 생성 여부를 조사하는 방식으로 수행하였다. 사멸능 조사에 사용되어진 에로모나스 하이드로필라 균주들은 본 발명자들에 의해 분리되어 에로모나스 하이드로필라 균으로 동정된 것들로 총 15주였다. 박테리오파지 Aer-HYP-2는 실험에 대상이 된 에로모나스 하이드로필라 15주 중에 총 14주에 대하여 사멸능을 갖고 있었다. 대표적 실험 결과가 도 2에 제시되어 있다. 한편, 박테리오파지 Aer-HYP-2의 에드워드시엘라 타르다(Edwardsiella tarda), 비브리오 안길라룸(Vibrio anguillarum), 비브리오 익티오엔테리(Vibrio ichthyoenteri), 락토코커스 가르비에(Lactococcus garvieae), 스트렙토코커스 파라우베리스(Streptococcus parauberis), 스트렙토코커스 이니에(Streptococcus iniae), 및 에로모나스 살모니시다 (Aeromonas salmonicida)에 대한 사멸능 조사도 실시하였는데, 결과로 박테리오파지 Aer-HYP-2는 이들 균종들에 대해서는 사멸능을 갖고 있지 않았다.
이상의 결과로 박테리오파지 Aer-HYP-2는 에로모나스 하이드로필라 균에 대하여 우수한 사멸능을 가지며, 다수의 에로모나스 하이드로필라 균주들에 대하여 항균 효과를 발휘할 수 있음을 확인할 수 있었다. 이는 박테리오파지 Aer-HYP-2가 에로모나스 하이드로필라 균에 의해 유발되는 질환에 대한 예방 또는 치료 목적의 조성물의 유효성분으로 활용 가능함을 의미한다.
실시예 4: 박테리오파지 Aer - HYP -2의 에로모나스 하이드로필라 균 감염 예방에 대한 실험예
9 ㎖의 TSB 배지를 담은 하나의 튜브에 1× 108 pfu/㎖ 수준의 박테리오파지 Aer-HYP-2 액 100 μl를 넣어주고, 다른 하나의 9 ㎖의 TSB 배지를 담은 튜브에는 동량의 TSB 배지만을 추가로 첨가하였다. 그 다음에 각 튜브에 600 nm에서 흡광도가 약 0.5 정도가 되도록 에로모나스 하이드로필라 균의 배양액을 넣어 주었다. 에로모나스 하이드로필라 균을 첨가한 후 튜브들을 25℃의 배양기에 옮겨 진탕배양하면서 에로모나스 하이드로필라 균의 성장 상태를 관찰하였다. 표 1에 제시된 바와 같이, 박테리오파지 Aer-HYP-2 액을 첨가해 준 튜브에서는 에로모나스 하이드로필라 균의 성장 억제가 관찰된 반면에 박테리오파지 액을 첨가하지 않은 튜브에서는 에로모나스 하이드로필라 균의 성장 억제가 관찰되지 않았다.
에로모나스 하이드로필라 균의 성장 억제
구분 OD600 흡광도 값
배양 0분 배양후 60분 배양후 120분
박테리오파지 액 미첨가 0.50 1.02 1.64
박테리오파지 액 첨가 0.50 0.25 0.16
이 결과로부터 본 발명의 박테리오파지 Aer-HYP-2가 에로모나스 하이드로필라 균의 성장을 저해할 뿐만 아니라 에로모나스 하이드로필라 균의 사멸까지 시키는 능력이 있음을 확인할 수 있었고, 이로부터 박테리오파지 Aer-HYP-2가 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방하는 목적의 조성물의 유효성분으로 활용될 수 있다고 결론지을 수 있었다.
실시예 5: 박테리오파지 Aer - HYP -2를 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환에 대한 예방 동물시험
무지개 송어(평균체중: 23.4 g, 평균체장: 15.8 cm) 20마리를 한 그룹으로 하여 총 두 그룹으로 나눈 후 수조에서 분리 사육하면서 14일간 실험을 실시하였다. 수조의 주위환경은 통제하였고, 수조가 있는 실험실의 온도는 일정하게 유지시켰다. 실험 개시일로부터 시험 전기간 동안에 걸쳐 실험군(박테리오파지 투여군)의 무지개 송어들에게는 1× 108 pfu/g의 박테리오파지 Aer-HYP-2를 포함하고 있는 사료를 통상적인 사료 급이 방식에 따라 급이하였다. 반면에 대조군(박테리오파지 미투여군)의 무지개 송어들에게는 박테리오파지 Aer-HYP-2가 포함되지 않은 동일 조성의 사료를 동일한 방식으로 급이하였다. 시험개시일로부터 7일째가 되는 날부터 2일간 1× 108 cfu/g 수준으로 에로모나스 하이드로필라 균을 급이하는 사료에 포함시켜 하루 2회씩 급이하여 에로모나스 하이드로필라 균 감염을 유도하였다. 시험 개시일로부터 9일째가 되는 날(에로모나스 하이드로필라 균 감염 유도 후 2일째)부터는 매일 모든 시험동물들을 대상으로 절창병 발생 상태를 조사하였다. 절창병 발생 상태 조사는 체표의 궤양 크기를 측정하는 방식으로 실시하였다. 체표의 궤양 크기 측정은 통상 사용되는 Ulcer size(US) score{정상(궤양 없음): 0, 약한 궤양(궤양 크기: 0.5 cm 미만): 1, 강한 궤양(궤양 크기: 0.5 cm 이상): 2}를 측정하는 방식으로 실시하였다. 그 결과는 표 2와 같았다.
체표 궤양 크기 측정 결과 (평균치)
US score(mean)
날짜 D9 D10 D11 D12 D13 D14
대조군(박테리오파지 미투여) 0.40 0.50 0.55 0.60 0.70 0.75
실험군(박테리오파지 투여) 0.10 0 0 0 0 0
이 결과로부터 본 발명의 박테리오파지 Aer-HYP-2가 에로모나스 하이드로필라 균에 의해 유발되는 질환의 예방에 매우 효과적이라는 것을 확인할 수 있었다.
실시예 6: 박테리오파지 Aer - HYP -2를 이용한 에로모나스 하이드로필라 균에 의해 유발되는 질환에 대한 치료예
박테리오파지 Aer-HYP-2의 에로모나스 하이드로필라 균에 의해 유발되는 질환에 대한 치료 효과를 조사해 보았다. 무지개 송어(평균체중: 23.6 g, 평균체장: 15.8 cm) 40마리를 한 그룹으로 하여 총 두 그룹으로 나눈 후 수조에서 분리 사육하면서 14일간 실험을 실시하였다. 수조의 주위환경은 통제하였고, 수조가 있는 실험실의 온도는 일정하게 유지시켰다. 실험 개시일로부터 5일째 되는 날부터 3일간 1× 108 cfu/g 수준으로 에로모나스 하이드로필라 균이 오염된 사료를 하루 2회씩 통상적인 사료 급이 방식으로 급이하였다. 에로모나스 하이드로필라 균이 오염된 사료 급이 마지막 날부터 절창병의 임상증상을 보이는 개체가 두 수조 모두에서 확인되었다. 3일간의 에로모나스 하이드로필라 균이 오염된 사료 급이 시행 다음날(시험 개시일로부터 8일째가 되는 날)부터 실험군(박테리오파지 투여군)의 무지개 송어들에게는 박테리오파지 Aer-HYP-2를 포함(1× 108 pfu/g)하고 있는 사료를 통상적인 사료 급이 방식에 따라 급이하였다. 반면에 대조군(박테리오파지 미투여군)의 무지개 송어들에게는 박테리오파지 Aer-HYP-2가 포함되지 않은 동일 조성의 사료를 동일한 방식으로 급이하였다. 에로모나스 하이드로필라 균의 강제감염 후부터 3일째가 되는 날(시험 개시 8일째)부터는 매일 모든 시험동물들을 대상으로 절창병 발생 상태를 조사하였다. 에로모나스 하이드로필라 균에 의해 유발되는 절창병 발생 상태 조사는 실시예 5에서와 같이 체표의 궤양 크기를 측정하는 방식으로 실시하였다. 그 결과는 표 3과 같았다.
체표 궤양 크기 측정 결과 (평균치)
US score(mean)
날짜 D8 D9 D10 D11 D12 D13 D14
대조군(박테리오파지 미투여) 0.95 1.25 1.45 1.55 1.55 1.55 1.65
실험군(박테리오파지 투여) 1.00 0.85 0.40 0.35 0.25 0.20 0.10
이 결과로부터 본 발명의 박테리오파지 Aer-HYP-2가 에로모나스 하이드로필라 균에 의해 유발되는 질환의 치료에도 매우 효과적이라는 것을 확인할 수 있었다.
실시예 7: 사료첨가제 및 사료의 제조
박테리오파지 Aer-HYP-2 액을 이용하여 사료첨가제 1 g당 1× 108 pfu의 박테리오파지 Aer-HYP-2가 포함되도록 사료첨가제를 제조하였다. 사료첨가제의 제조 방법은 박테리오파지 액에 말토덱스트린을 첨가(50%, w/v)한 다음에 동결 건조시켜 제조하였다. 최종적으로 고운 가루형태로 분쇄하였다. 상기 제조과정 중의 건조 과정에는 감압 건조, 가온 건조, 상온 건조도 대체 가능하다. 대조 실험을 위해, 박테리오파지가 포함되지 않은 사료첨가제도 박테리오파지 액 대신에 박테리오파지 액의 제조 시에 사용한 완충액(Buffer; 10 mM Tris-HCl, 10 mM MgSO4, 0.1% Gelatin, pH 8.0)을 사용하는 방식으로 제조하였다.
이렇게 제조된 2종의 사료첨가제 각각을 중량비로 250배의 양어용 생사료와 혼합하여 최종 2종의 사료를 제조하였다.
실시예 8: 약욕제의 제조
약욕제는 다음과 같이 제조하였다. 박테리오파지 Aer-HYP-2 액을 이용하여 약욕제 1 ㎖ 당 1× 108 pfu의 박테리오파지 Aer-HYP-2가 포함되도록 약욕제를 제조하였다. 약욕제의 제조 방법은 박테리오파지 액 제조 시에 사용하는 완충액 1 ㎖ 당 1× 108 pfu의 박테리오파지 Aer-HYP-2가 포함되도록 상기 박테리오파지 Aer-HYP-2 액을 첨가하여 잘 혼합해 주는 방식으로 제조하였다. 대조 실험을 위해, 박테리오파지가 포함되지 않은 약욕제로는 박테리오파지 액의 제조 시에 사용한 완충액 자체를 그대로 사용하였다.
이렇게 제조된 2종의 약욕제는 부피비로 1,000배의 물로 희석하여 최종적인 약욕제로 사용하였다.
실시예 9: 무지개 송어 사육에서의 사양 효과 확인
실시예 7 및 실시예 8에서 제조한 사료, 및 약욕제를 이용하여 무지개 송어 사육 시의 사양 결과 개선 여부에 대하여 조사해 보았다. 특히 본 조사는 폐사율 관점에서 실시되었다. 총 400 마리의 무지개 송어를 200 마리씩 한 그룹으로 총 2개 그룹(사료로 급이한 그룹-A; 약욕제로 처치한 그룹-B)으로 나누어 4주간 시험을 실시하였다. 각 그룹은 다시 100마리씩으로 구성되는 소그룹으로 나누어지며 각 소그룹은 박테리오파지 Aer-HYP-2가 적용된 소그룹(소그룹-①) 및 박테리오파지가 적용되지 않은 소그룹(소그룹-②)으로 나누었다. 본 시험에 대상이 된 무지개 송어는 5주령의 무지개 송어(평균체중: 23.8 g, 평균체장: 15.9 cm)였으며, 각 시험 소그룹의 무지개 송어는 일정 간격을 두고 위치한 격리된 각각의 수조에서 사육되었다. 각 소그룹은 다음의 표 4와 같이 구분되고 지칭되었다.
무지개 송어 사양 시험에서의 소그룹 구분 및 표시
적용 소그룹 구분 및 표시
박테리오파지
Aer-HYP-2 적용
박테리오파지가
적용되지 않음
사료로 급이한 그룹 A-① A-②
약욕제로 처치한 그룹 B-① B-②
사료 급이의 경우에는 실시예 7에서 제조한 사료를 표 4의 구분에 따라 통상적인 사료 급이 방식을 따라 급이 하였으며, 약욕제 처치의 경우에는 실시예 8에서 설명한 약욕제 제조 방식에 따라 제조한 약욕제를 표 4의 구분에 따라 약욕제의 희석액에 어체를 담그는 방식으로 실시하는 통상적인 약욕제 처치 방식에 따라 처치하였다. 그 결과는 표 5와 같았다.
무지개 송어 사양 시험에서의 폐사율
그룹 폐사개체수/시험개체수 폐사율(%)
A-① 4/100 4.0
A-② 13/100 13.0
B-① 5/100 5.0
B-② 17/100 17.0
이상의 결과로 본 발명에 따라 제조된 사료의 급이와 본 발명에 따른 약욕제의 처치가 무지개 송어 사육에서의 폐사율 감소에 효과가 있음을 확인할 수 있었다. 이로부터 본 발명의 조성물의 적용이 무지개 송어의 사양 결과 개선에 효과적이라는 결론을 내릴 수 있었다.
이상의 결과로 본 발명의 특정한 부분을 상세히 기술하였는바, 당업계의 통상의 지식을 가진 자에게 있어서 이러한 구체적인 기술은 단지 바람직한 구현 예일 뿐이며, 이에 본 발명의 범위가 제한되는 것이 아닌 점은 명백하다. 따라서 본 발명의 실질적인 범위는 첨부된 청구항과 그의 등가물에 의하여 정의된다고 할 것이다.
[수탁번호]
기탁기관명: KCTC
수탁번호: KCTC 13258BP
수탁일자: 20170510
SEQUENCE LISTING <110> iNtRON Biotechnology, Co. Ltd. <120> Novel Aeromonas hydrophila bacteriophage Aer-HYP-2 and its use for preventing proliferation of Aeromonas hydrophila <130> KP090537 <160> 1 <170> PatentIn version 3.2 <210> 1 <211> 236916 <212> DNA <213> Bacteriophage Aer-HYP-2 <400> 1 aacactccta aatttactac caactaccgc ccttactacc tcaaagccag gttcagcaag 60 atagataacc ctaccattat ggagatcttt aaaattcaaa cgtgtgtttt tcatttctat 120 ttttccttgc ctacatttaa ggtttaagtt acattaattc agaaataaca ttaatcattt 180 ctttagattt agtttcaaac acccccgtcc tccctatagc tattagaggg aaatagaaat 240 cttctttaac aacttgtttt gatttggggt ttgtaattaa aactgataga tgttctttgt 300 aacccatgtg aggttctagc tttactaata ccgaggaacc attacataga ttgaaccttt 360 taaaatcttt atgtcgagat gcactaaaag atttgatact ggtttccagt ccgtagaaca 420 atctttcttt acctttatcc gtaaggtttt caaatactgt ttccattaga ttatccttaa 480 aaactgttga aaccagagag aacccgattt ctaattcttt ctgaaagaac atctggtgta 540 actaatcttc catctgactc ttcaaacaaa catgttaatt caccaaatga taaattacga 600 agatccactt ctgaaagttt accagttact gtcagaacga tgacttccca ggattcttct 660 ttatcacctt cctttgtaca acacttcttc cacaaagctt gttgcaaagg ggtaatgaat 720 ttatcttcag gaacttcgtc aggataaatg aaacgttgtt catcctccaa ccacactggt 780 atagagtgac caaaataacg aagatcacgt tcaattctag atttaccagt gtattcgtat 840 ttaccgcgtt cttcatcggg aactacgcga atagctacaa cttgatcatc ttcaaccctt 900 cctgctgaac caaaccaagc acaagcattt ggctgcatct gttttagtat agtaccatcg 960 tgaagtttaa tgtcgtgaag actctttact cgccacccgt tatacggaat ccaaacaccg 1020 gttacaaagg tattataatt aatccgattg ttgtaaggga aattactatc catttttatc 1080 tcctaataat cttttcaatt cagagccaac actttcaggt gtaaaccaaa gtgcaatcaa 1140 ataagaacca gcgcgaatac cgatctcatc atgcagaatc cagacatttg gaactaaaac 1200 taattccaga tgtttaattg catcctcata gttaatacca ggttttgcta ccaacaattc 1260 aggtttaatt aatccctctt cattataaat agtacaaaga gaaacaaatg gatatttaaa 1320 ctcttcctct gtattccaga actcccagaa aggtgttgga tgagggagca ggtgtttagt 1380 ccaagtatcg atattgcttt tatcaatagt tgaaacaata tctttactaa taggtaataa 1440 tttcaaatta ggatctggca taactttatc cctttaactt ggaatgaatt taattcccga 1500 ttgaactaga aactgtctta acactaaccc tacttcactt ctaagtaatt taccttgttc 1560 gtgattagtt ttaggattag ataagtttcc catccaggtt agacttacag attttctcat 1620 tccagtttga gaactaatgg tgaatgacca ttcgtgatta cgaggattaa ctaaacgaaa 1680 ctctagttta gctttaacac tctcaataga cagttctggt ctatgactag ctgtttgcca 1740 gaaccgtaaa tgattatgct gtttcaatga tctaattaag ttatcttcta cccagaaacc 1800 gactccaccg gcactaatga tggagtcaat gatctgatta aacacgttcg cagatatggt 1860 actcattaca agttcctatt tattatcaag ttctacatca atgctccagt cagcaaagaa 1920 cttagctaca gcgtgttctt cagctttgat gtactgatca ttcttgataa aagcaccatt 1980 gcgacgagta atgttaactt tgaagcaagg tttactagga tcaatttcag cgttactgac 2040 ttgtgtcata gtgaggtatt gacgacccat gtgaccagaa caggttactt ctttgccgtc 2100 ataatgcgca acgatctcga aagtacctac tgcaaaagta cttccaccga tacgcagttc 2160 acctttgcca tttagagcag aaacctgcat ccgaaactct gacttttcgt tggtcatcag 2220 ggaagcgagt ttatcaatgt gttgttgttt cattttctat attcctttta tctagactaa 2280 ttaagttggt attaaagatt acaaagttga ttcaatacaa cttggtgaag ttgatgcgaa 2340 acaatatttg caaccttgtc aatgttatta gatttacagt aaatggtatt aaggtaatat 2400 ccagtactgt cttcccagta gtttttaccg ttctttaaaa acaaccaagg ttgaatccaa 2460 ccctgcttac tatcagcatg tagtgtaact gtaagatgaa gtttatcgga aaggcaaaga 2520 tccagagttt cacctgtatt ataactggct tcaaaactag atttgagaaa tgcttcaatt 2580 tttgcttgac tattaactac acttaactgc aactgattca tctaatccct ctcccataat 2640 cccagaaaac aactcatcaa gttcgtctac actttcttct ttattcaaaa taaaaccatt 2700 taacaattcc tcagttagtt ccaccatatt actacaaaga ggaacactct cagaacttcc 2760 tgtaacctcg ctaggatcct tcagaatgtt atctagtacc ttatatccgt ttacctctgg 2820 aatgttatca gaagtcatct gaaggtcttt actgacggtg aacatggcgt taattaaatc 2880 accatccatt ttatcaaaat taagatcatt tccgtagtta atgtaatacc catggtgaga 2940 gtaataatct ttaaggtctt taaactcttc agtttccaga atacaaactt tagtttcctc 3000 tattaaagca ggaactagat cacaagcaat acctaaagtg aaatctggaa ctgtgcaagt 3060 aaccgggatt acctccacta tcccatcaat atcaaagaaa tgataaatag caatcaccca 3120 ggtattagga gtatcgagca gaaacttcat agcttcttct aacccgattt taagatcttc 3180 tccttttaat cggttcttaa gttcacacaa cccaaaggtc ataggaagat gattcttatc 3240 accgatgatg tagaacttac ctagagcgtg attaagagat tgggtaatgt gtgtaacttt 3300 agcacgatga gcaaagaact gtttgtggac agcaatggct tgtttcttct tctgattttt 3360 agcttcattt ctctttttct tattagacat cgtagtttcc tttatacact cctagattta 3420 cacttaaata atatctactt gaaaaattat agaacaggta aaatagtgca actgggagtt 3480 cccagttgca ctctaactta gtggtaataa cctacataat cattcttagg taagattact 3540 aatttaccag ttccattatc ccgtaaaaga taatcacctt ttgtaggaat aaattcacgg 3600 tactttatag agttctcatt tgtataaaga tgattatcat tggtggtttc caatagaaaa 3660 gcaaatttat cgcgtgagaa aattagtgta tcaaacccat ccttactctt aaccgcagtt 3720 acctctccaa caaactccgc ttcgttacta gcttgatatt caccaataac gtacgtattg 3780 caaagaggtt tgagttggat ggtgataaca gtttcaattt tattagtttc acctttatgg 3840 taaacataat gttgatacgt tttattgaag ggattacttt caataaactc tagaaactgt 3900 tcgagttcac tattccactc ttcttctgta agagtgtact tagagttttc atctaagttt 3960 aaatgaggag ttattgtcaa gtctctcata aactgaaaag cgttgtctag ggcggaaggt 4020 ctttcatctt caatccgctc catgcaacct aagtctccat caaaacaggt tgtaataaac 4080 ccattccaag agttaccttt cagacctaag aaagaaacct tgccttcacc agaaatatga 4140 agaaataaat ttccaaattt tctagttaat cgttctaacg tatcagtacg gatattcatc 4200 ggcatattca aagtcaccag gattcagagt gtcgatcaaa gcaaacactt taaccttaga 4260 tcgaatttga tcaattgtag tttgaacaac atccaccacg atttgatcag gttgatgttc 4320 gggaactttc ccctttccgc cagcgttaaa agctacgtta taagctttat cggcagtatc 4380 gcgaccaacc aacggatcta gtgccctcgg agaaccaaag gtcggggttg ggtaccatgg 4440 ggagataggg gtaatttcgt gcaaagtagc ggtactaatt ttacccaaca tctccacagc 4500 tgtgaagtgc tgattaccta ccaagattcc actgcgaccg actcggacaa acggaacagg 4560 agttacccca gtgatataac cgtagtcaat acgtttatcg ataacgattt tagagttaac 4620 atctaatccc tcgcaaagag tatgaccata attaacaagc ttgaaatcac taagagtggt 4680 ctttccaatg gaaagattaa tcaacttctt atttggtaaa tcaagaatga aagagttatc 4740 attatgacaa taacaactac tgttgtaaat gttgatggaa ttaaaaccgc tcagtgaaat 4800 ccgactcccg ttaaactggt taacattgag agagtttgca cgagtaatac tgaaaacact 4860 tagatccata tttgtaagat caatagagtt ttcaatctcc actttaccgt ctgacaaaga 4920 aactttatca atggttaccc aactacctat taaccccaca ttaaacagtc gattctcttc 4980 aaaaccacga acagaaagat tttcggcagt gatagtagag tacgctactt taacacaagg 5040 tttacgtcca tcggtgttgg agttactgta cactgtttga ttatcaagac gtttaacatc 5100 tacaacagaa ccttgggtca ggaagaattg gatcccgtta acttcagcgc cgtaccactt 5160 aggttcaccc tcaacctttt tcatttcatt ttcagtgtag tgattactaa agcggaaaag 5220 tgttggacga taacggaaac cattattgtt aaagaaataa tcgctggaca gttcaacttc 5280 tttaagttca atttctttat caccaacact cagctttggt ttattggtga tgctatctcg 5340 gatgtacttg ggtttaacct caacattttc taattctaca gaggggagtg tttctggttt 5400 cggcagttcc gagaaatcga aagtagcttt tgattgatct ttaatttctt caactacaac 5460 ttcagtagtt tctaccggag caacttcagt tactttagct tctttgtttt tcttagtcat 5520 ttcattgttt ccttttacac tgcggcatgg taaagttggt atccaactat ccctgttatt 5580 acccagaaca ctactgtaat tacaataact gttccggaac gttttgttaa tttcatttta 5640 acaaatctcc taacacttag cgtataattc tcctactagt gtttgttcac tgtgtagtgc 5700 aataaaagat ttaagtttat ccaaattagc ttgtcgatag aaacaagtgt attcagtcaa 5760 ctcttcagta ataaatatta accactcttt acagattttg attacaagtt gcttaaaggt 5820 actgtttaga acttccacgg tgttagggaa cacagtaact gtttcatcgt gtttgatcat 5880 attgatcaaa gttagcttca actcttccgg gaattgctga ttaaactccg ggaatgtttt 5940 aatgagttgt ttctctacac attcactatt agatagaatt tctttgatca tctctttata 6000 ccgctcgagt cgttacgttt ttgctagatt catgtttgtg ttgatgacgt gtcatatcaa 6060 tctgacgaat aactggatca ttgtcatact tcggtaaaga aacgtctata gttttataac 6120 cattggaatt agcaatcacg atggaatatt ccaatcccat tttatcaaca caggtaataa 6180 gacgatctaa actcatctta tcaactttct gaagttttag ctcagaaata gtactggggt 6240 tgattttgta cttggtagcg agatcaacag ctttctcacc attccggatt tgtaagttaa 6300 taatgtagct tacacgggtc attaaaacct tctttacttt cattaaacta tcgtgtttaa 6360 aacgcataat cattctccta gactagttaa tttggtaatt gtttcaccat aactattatg 6420 ttttaaagtc atggtccgga tccttgcctc caatagtttc ttgttaattg tcaacattct 6480 gttcacagcg gtcgtttttg ggtgatccaa cttccctgtc aatggattgt accttgttaa 6540 acgaccacca catccgcgac cagaaatagc acagacgtat gaaaccactt ccacagagct 6600 tttaaatacg tcacctattt tcatcctact cggtaactga tatgatgttc cggctgtgac 6660 ataatagctc attttgatcg gaccattcca ttctcggtaa agagaggtgt tattaccact 6720 acttcctagg taaatactca gtgatgttgg tgttttgtta ccatcgctat caacttccac 6780 tccaacacca actacatcgc agttaaattt ttgtttgaac gtcgtataaa atcgttttct 6840 aaatacatga caagtttctc cagcttctac agagcggttt atttcagcta ttaccatagt 6900 tatatcatcg gaaacaccgg cactagcaat agcggtaatg tttaatgtgg gagagaactt 6960 ccatggttta gaaagaactc taatcttaat aacatcatca gtatccatgt actctggaat 7020 atctttatca ttgtaactgc gtttaccatc cgttaccaaa tgtttcccat caaatacaat 7080 aattgtcatt ttcttcccct atactgtttt ttgaaataac ctacttggtt taccatctta 7140 ataatatcta tctgaaaaaa tatagaacac agtaaatttt taattataca ggattaaaac 7200 ctacctaacc aattacggtt aggtaggtta tttttattta atagaacacc agatccacat 7260 ttcaagaaac ttaagtagtt taataacttg tttctcaaaa ccgatttcaa tatccactac 7320 agaactagtt acttcacccc agttgatagt gctgaaaagc tctttctcgt atttagaatg 7380 tttctcatgc attcgatacc agaagtcgga accatcacga tcgtcgtaat caataccagc 7440 tgacaataaa tcaactgtct tgccctcaaa tccactggcg atgtcacaca gttctgacat 7500 tactttaaca gcttcttttg ccccttcctt atttaacaca ggaagttcac cagctacttc 7560 attggaaaga ttaaacatct ttacaacttc atcaatacta gtgtctttaa gtttttcagg 7620 tttaatcgga aagtgtttag ctaattctga ttcgtattta tcaaaatctt ctttagataa 7680 agtatctggg attttaatct tatcgtattg gttaaatagt ttcaaaccgt tgcttaaacg 7740 tgctgaacta ttttggtgtt gtttctggta ttcggattgg acttgtttaa gagaagattc 7800 aatgatcttt ttaacaccat ttggagtatt gacttcctta aaaatctcag gtaatttaaa 7860 cttagcttta cctacgttct tgaaagtcat ttgatttaac caagcatcag ttgcgtacag 7920 ctgaagttct ttcttggttt tatcaatatg tccagaaact ttactcttac gatctttaga 7980 tttaaaccac tccttgatct ttccccaacc tgatttaagc ttttctacta aaccttccat 8040 accggcgata tcaggagtaa catcttcatt gtaggtttct tttgcataag aggaaacttg 8100 attcaacaat gactgttcat cagaactaga ttcacaacca tcgtactttt ctttgttcat 8160 taggatattg gtttcaatga gttcaatatc cattttagct tttaaataaa actcttttaa 8220 ttgagagttt tgaaattgat taatttgcat aatagttcct ttatataaac ttatcgcaaa 8280 taatcattaa ctcagatctt atgaactgat tttaaagaag cttaaatgac ttctttaact 8340 acctattaat caaagaggtt ttatatgatt ttcacacaaa accctattgg atcttcagca 8400 actgaagact tacaagacaa cgctatttcg tttgattatg cgatgaactc tccagctgct 8460 ttgtggcagg atcgtttcgg taaacaacat aaaactgtac aacaggcttt gaaagatgtt 8520 gggtttaaac cagctggttt tgattttgtt agtggtggta ctttaggcat tggtgatcgg 8580 gataaatgtg tcttttatcc aactgatgga tattggtaca gttggaatgg taaactacct 8640 tacgtagttc cagctaatag ttctcctaca cctggtggta agaaaggatg gggagtgatc 8700 gagcgggggg taaagacatc attattaagt tacgatacca ttcatgtatt actttcgtcg 8760 ccaactaaga caaattcgga ctcaatgcac gtcatggagt atcgtgctgg cacaggttta 8820 ggtggtggat tttttattta cgatccagcg gtccctaaaa cgtcgcacaa tggtggaaca 8880 atttttagcc caacagtacc ctgggacggg tctttggaag gattggacaa ttttgttaat 8940 gggaaagacg agaaagataa aaatggtaca ggttgttacg tacgtatatg tagtgatgtc 9000 aaggctgagt attttggatg ttttaaatct attactgaga attgttcagc tagctggaat 9060 gccgccaata tccacgcggc taagacacac tctgagttag tattgataga tggacccata 9120 cgaattgatc gaacatgtgt ggtggatggc gccattaccg ggtttcgaac tataaaacta 9180 aaagggacgt tcagcggaac tggcgtttca ttgaactaca ctccagaaac taacggtagc 9240 gtggtaatga cagaagggat ccccgccctc cttttaaagt ttaatttatt ttctaatgag 9300 aattatacaa ttaaaggtgt cgggttcata gactctagat attaccctag aggacaggcg 9360 ctggcccaat cagccccgat aaagatagag aaaggtaatc ccgacgggag taacattaga 9420 tatataacag gtcacgtgtt ggaagatgtg gcgttctccg gttatgctgc aggggtagaa 9480 actgtgggta tgggtgaaac gatatctagt aatttcattg gccctactag ctgtcttaga 9540 cttagtacgt acaatcaagg tgatttattt aggtgtgtag atagttcgtt aaaccatttg 9600 tggatcactg atagtaatct ctttagttta gatgggtttg gggttaattt agttaaaaca 9660 ccaaaaggtt ccggggggtt tgcggacgtc acgtacaata acgttatgat agagggtgcc 9720 aggggactaa taaacactct cggtcatggc gtcggggttc gaagtcgttt agttatgaat 9780 tctgtaaacc gagagtcttg cggattttac ggaccaaatg ttaacggtaa atacaccggt 9840 aatcctttag gtaaagttgt cgatgtggat atagtgataa gcggtgtatg gacagaagct 9900 ttggctttta atgaagaatc tttaccaatg gccgaacaag gttccaaagt ttccagttcg 9960 gtaccggcta acttcttatt tctagctggt tcaaagaact taactccaga attagttaat 10020 tattacgaaa ccagttttat tttaccaact ggtactaccg tatcaaagtc tgtcattggg 10080 actggtacag acgcaattga cgcaagtgtt aggatcgttc taaatgatgg tagaagaggt 10140 gttaaacatg taaacatcag cggttacatc aatggactaa agctgattga tgaaaatggg 10200 ttaaaagatc ctttaattga gattgtcttt tcagatggtt catctacaag tatctgtgac 10260 ataaccgtaa ctaacaacag tccctctatg acatcagtaa agttagaggt aataaatagg 10320 aacggtatga atacttatgt gctttaaaca ctcttggata atccaaccca aaaatatata 10380 agcctcgtta attcaccacc aacgttataa cgttggtggt gaattaacta tttcttttta 10440 tatttcagcc accagggttt ctttacagca cccagtttaa cttcattagg atcaggagga 10500 atataacctt catcaactaa tgttggattg ccagcagctt ccttagctaa agtgtcagcc 10560 ctttcattac cgggaatatt agagtgcgcc tttacttttt caaacgtcac tgtgtggaac 10620 tttactaatt taaacaatcg ttcaaataga tctttgttct ttacaggttg tccttgagaa 10680 gttacccagt cattcttaat ccaaccatag atccatttag taacagcatc aatagtgtac 10740 tgagaatcac ttcgtatagt aactttagtg ggttcttgaa actcctctag aaaagagata 10800 attgctaata tctccatcct attattagta gtcttaaaat acccacatga cttctctact 10860 atcaattctc cgaaaatagc gtgaaaaccc catccgccat ttccaccatc agtggtgttt 10920 tcacctaatt ttgaaccgtc agtgtaacaa acccaacttt tagtctcttt acaatcttcc 10980 attacaaact ccttatgaca aggcgtctaa agcctcctgt aaagtcacag ggagtgcttc 11040 tttagttttc tcactaatta ccactttact accaggacat tccaagtgtt tatggtagct 11100 tgatgtcata tacttggtta cataataacc attactgtat tttctcatgc accaataaac 11160 cttaccatct atagattttt gaatatcgcc atcatcaaat gggatatcca cccaattttc 11220 gacactggaa tgataaacaa tacctaatga ttgaaaacaa ggatacagca atccgacgac 11280 tttatcgagt tcgtaacttg gttttaaata accaagaaca accatgtttg caacgaagtc 11340 aatcattttg atgttcttat agtcgatcca gtcgtctaca tgttgcactt ctttaatgga 11400 taaaacttcg tcaccattga taagtaactt aacacctatc tttacactat ttcctaagtg 11460 cgaaaaacca cctgaatatg agctaactgt aggacaaatt tccacaacgg tcttgttaca 11520 attgataaag aacccgtgtt tatacacgat caattgatcg actatctgtt cctgaccaat 11580 tgagggatct ctgaccatct gtctacgata agtgacagct tctagtactt cttcataaga 11640 cttgagcttt tcttgaaaca tatccatttt agaattcctt ctgagtaaaa tctggattag 11700 aactaagagt tggtttagga ataaaaccac ctttctgttt aattagggta gttctaagct 11760 tcatagcttc cttaaagggt attccgtctg tagtgaacac aaaactatca tattccccgt 11820 tttcaataat gtccacttta cagatgattt catcaggatg agtagctggt cgaggcttta 11880 ttatcctaat gcatttctca ggacctaacc aaatattcct ttccgcaaat cctttattat 11940 taagattaaa ctcatcaata agtttaatcc aaagggcgta aagatcagag atcttcggtt 12000 tgactacccg atgttccaag ttaaaaatat cgtacaaagt cttatcatta aaataccaag 12060 ccatgtactg taaaatttgt ctactaaaat cctgattagg ttctccattg atgttatcat 12120 gtataaccca aataagagaa cctagttcta gtttataagt aatagagttt tcagtagaaa 12180 tgggtgttaa aatgatctgt tgaccgtcta ctattccaat gattggattg tatacagttc 12240 cgttagcaag tccatctctg atcttaaaca actcttcagc aaactttgac atctcaccaa 12300 atgtcttttc gggacagatg tggaaacaga aatctattaa tctagcatta aacatttctg 12360 gactcctatt attttaatgg gtaattttat tttccatcat tttcttagtt tctttgatct 12420 tattaagaat ccaaggatcg gtgtcaggat tctccagaat ctctttaatg aaatctggat 12480 cagcaggata ttcttgtgct aacataaaca caagttcttc ttcagctgga ttaggatcca 12540 tagaaacaga ataggtacgt tcattccaat ctttgatcaa agctggattg attaacgaaa 12600 tagcttcagg ttcaaacaga tactggttat aaccccagtt tcctggggta ggtttaatac 12660 tggtattata gtcaaccttg gtggtgccaa tcaggtgttt acgaaaccag tactctggat 12720 tacgtgggtc aaacggattc agtttaggat ctcttttcat tatttatatc ctcgtacatg 12780 atcgcataag aacttctcaa tatcagcaat actcttcaaa gggtttgcga tctgagtgtg 12840 gatgtgataa gcattcccgt gttcaatctg attacgatca gtaaagtctt ctgacttttg 12900 attaattttc tttacgatat gagtaacgaa ttcacgatgc ttgatcttac gatgaacttc 12960 gtaagtaatt tcattacctt gctcatcaga ggttgaaagt ttaccactaa taccacctag 13020 aggtaaccga acccattctg tttcaccagt actaagacct gaaggagttt tcctaccttc 13080 cacaatttct atatattcgc ttaacaactg gaagtaggtg tgacgttgat tagctagtag 13140 acgtttatca aacccaaggt tgataccagc tatgtacttc ttaacgatct cagtgatccc 13200 tggatagtca gttgcaaaac tgatatgacg ctctacccaa agtacagggt caccttcatt 13260 gttaaacact ttagtggtta cattatcaga tacgaatact agacgttgtt ccccgttaaa 13320 gatatcaaca cgacgttctt tttcaccaat ttctacatca atgatcaatg acatggtaaa 13380 ttccttttaa aagagtttct gaacagcgtt agcggtagct gaggtatcaa caatagttct 13440 ggacggagat acgaaaacat agatgttatc accacgatcg tcacaaccgg tttgtgttac 13500 aaccttacaa cacataacgt tggccagttg atcaaatatc tgattattag ttttctgacg 13560 atccagtacg atcactacga tagtacgttt ggtgtaatca taaatacgaa cgttatcgga 13620 accatctaaa gctgcggata ggtctttaat ctggcgatca gtaatatcag atttaaaggt 13680 caggtggatt ttcatagagt ttggcataat ttcttatctc ctagaataaa ttgaatactt 13740 tcatataaag ttgttacagt aaacaaataa ataaccttac actccgagtt ggagtgtaag 13800 gtataactta tttaagtttc tttacgattt gatcaaaagt ggtcataggc gtaatttcta 13860 ttacagggat attccatttc tctgctttag caatcttacc tggactaggt gctttaccga 13920 ccaacagttt agtgatactt ttacttactt tatcagcaag ttcataacca gcttctgcta 13980 gttgttctgt taactgataa cgagtgatat tccaagatcc agttatccca attggaatta 14040 acttatcttg tactttaatc tccttatcaa aatcgtaatg aataaagaaa ttgaccaact 14100 cgttttcatt actattaaca tactcgcaag ctactacgcc atctaaacca aaaagttctt 14160 ccattacttt ctgatctttc atagctgcta agaaagtatt taattcagtg aacaacaccc 14220 cttgttgatc agccaattct ccagcacgaa cgtaaccgat gttgggaata caagctgcaa 14280 atatccagtt ttgtaaagat agtttactag cgttctctac ttgatcaaca attgatcttg 14340 cagtgttctc atcaaccaaa tctagcttaa tataatcttc aaaagttatc ttgaagatat 14400 cactaggttc tgacaagtaa ccagcgtcca ccagagccgt tatacgagca cttcccaacc 14460 caagtatatt cagacccttc ttctcaccca aacgttctaa atgagagatt agtagtccta 14520 cacagctgtc gttaacacaa cgaaccatac taggtgactc tactactaca ggttgattac 14580 aacatggaca gaatttaggg aactctacct tcttaccggt tccagcttcc ttcatcccaa 14640 tgatgttagg aatgatttca ttagacttag taatctggat cacactccca attcgtaaac 14700 catctttgat gtacttatcc ggataatcga atttagcacg tcgtaatgta gtaccgtcgt 14760 agttaacagg ttcgtaaact aatgttccag ttaaataacc tttggtagtc aatccccact 14820 ctacaccaat cagagtggtc gtcatcgaag cagtcggaaa cttataacaa gctgcgtaat 14880 tccaataacc ttgcatcttg tcatctttcc aaacacttaa gtcatcatcc ttaacaacga 14940 tcccatcaat agcgtaaccg aaattaggtt tctcttttaa tgagaacagt tcattaagta 15000 gacttccgtt aaacggcatt gggatatcaa atcccatatt aaccatcagt tcacgaagtt 15060 ctggataagt actaacttta tcccttagta ccttacttac attataagct ttaaagtaca 15120 gataaagtgt gtctttctcg ctaggataaa gacgcttcat gataccagaa caagtagttc 15180 tactttccgt ttccttagga tcaagatccc attgttcaca gtaatcaaga agatccttat 15240 aagtgcagta accttcacca gttactttga aataaggaat gtctttatac tcagggattt 15300 cggtgggaac atctcgcaac atatgaaggc ggtgagtaac atcggtacct tctaacccag 15360 taccgcgcaa atgaccctgt acgagcttac cgtaacgata gactaaccgg atagacaatc 15420 catccaattt ctcttcgtag cttacagtgc cctttacatt gcgtttacgc cacagttcaa 15480 tatcgtcacg tgttttcttc ttaactactg agatcatggg ttcatcaatg acaacggttt 15540 tcaaaccact gttgtcttca atgaaaccag gtggtaaccc tggtcgataa ccaggattct 15600 ctttaagtag ttcttcgcgt ttataaacca gctggtcgta ttccgtatct gaaatggacg 15660 gtttatcagc aacaaaatac aaatagtcgt gataacgaat tttagcttcc aattcaagaa 15720 gctctttaat accgtttttc atattaactc cttaaatcgg aagtctggca ttcagtcgat 15780 caatgatctc ttctattgca aattcattgt tcattacaaa agaagtaacc tctttataga 15840 acgcttcaac ttcatggact gatagtttac cacgttgttt agctaccaac agtccttttc 15900 tgactagcga aacaaaatcg tcattatctt taactttctc tttgaggatg acacgtcctg 15960 ggacatattc ttcaccaacc agtaaacggt actctagaac aaaagagtaa tctcctagtt 16020 tgtcaactac aatgtgaagc tttagaaaga ctatattatt gtcttgttca tctacagatt 16080 gttcaagatc aacataaact ttctttacca attcaatcac tgcattactt ttgtgtctgg 16140 aataccaact ctggttctcg tattggtaca tcaaaccagc tgtaaacaat ttcagttgtt 16200 tactaatacg tttccttggg ttagtacgac taaactgctc acggaactgt acaagagctc 16260 caaagtcacc ctctaggaga ccaccactat tatcaatcat ctcactaacg tgattttcca 16320 aaatacgcat tgtaattgga gtggtgtgag tagttgtgtg agatttgatg taagcgttct 16380 ttacatcaca caaggtcatc aacaaggtat agatgtttgc agaacttctg gaaatagtag 16440 caacgatttg attagtacta ttttgaaata caaccaagcg agtaacagtg gagtcaaaat 16500 gtttcattat ttaatcccct taatgtgtgt ttacatactg aacaattcct tgtgcagtac 16560 gttttaattt atcatgatga tgattgtgtc cacgtagact agactgataa gtacctttgt 16620 cagtttctac tttaactaaa gtgaactttt cgaagtttaa tacaatctct tctctttcgt 16680 atataacagt agtacccatt tcttatccct agaatatatt taagttatta ttgaatctat 16740 acagtaaatg atccaactcc actttgttac tacgaagatg agttgagatc aaattaaaga 16800 acttttcttt tctagctata gttcttaaat ctagctgtct acgaatctca gataaaatcc 16860 cttctaggct ccattgtccc aatacatctc taaatccaaa cgtttgaaca cctaacacaa 16920 agttagcact aacgtgacgt ttaccttgag agaaaccaaa ggttagaatc aacgcctctt 16980 tttcacctag attaactttg tagttaaagg atgatttaac actattaacg tttcctagct 17040 tctcatagtc gtatagtact tcttttatgc aactatggaa taaagttaat agattacctt 17100 tagttctacc ctttcgaagt tgtttaagaa aatcgtctac aactacttta atttcaccag 17160 ggaaactttc ataatcagct gtaacagttt ctataaagag attataaact ttctctctac 17220 cgggtttagc ttcgaattca aatccgacat tataacagac atcggtctga gttgggttaa 17280 accaaacatc aaaagagaac acaccagtta ttaatctggt aacttgaaca gatgtattcc 17340 caactttggt agttagaaac gatttagaat aagaacgtac tttgttataa ttcattaata 17400 ttccttatct agactttgga taaacataac tctagagctg accaagtggt cagctctaga 17460 gtttaacctt tacacttaac attacaaaga ctgaatgata ttgtcaattg atctaatggt 17520 aacaggatcg gtacttacag gcgtatagcc attaatacgt gtaccagtta gatcgtaaac 17580 gatgaatgct tgcggttggt tattccaact caacacccca gttgttccac ccactggatc 17640 agaactaact gctaaagaaa caattacacc gttactaaca ggagaaggga caggagaaag 17700 ggtgtaatcg ttattaacga cgcaatgaag ttgctgcaac atagcaataa taccttatga 17760 aaatgaaaat tattatatct tgttcagaac atcaaggtcg tcgtattgtt ttaaccaaat 17820 ggtcgatctt gatatcgact cagtttggcg atttccagta ctggattgaa atcagttaca 17880 acctgtttga tatcacggaa gaactgtttc atctggtact ttacaatacg ttgttcataa 17940 acctttagtt cagcttgagc aatggtatcc atgaactgac ggaactccct tgctgtacgg 18000 acttgtccat taggtttgta atagtaacga ctattaccct tatggagttt gatgatctga 18060 ttaattggtt tatgggaata ggagttaatt agtttaagtc cgccatctgt tccgacgaaa 18120 tgaagaatgt atagatctcc aagtcgaatt gtctcattgg tcaagtgagt cttctcgata 18180 atggttttct tggtttcttg catatcttta gcgccaatca gtagattggc ttttacatca 18240 tactggtgtg cattaggctt aatacctagc tctttaccgt agagtttctt cttactcttc 18300 caagtaccac tagtgtactg gagaactcct gctgcggtgc tgtgcgggtt cttagctttc 18360 actcttagtt tagattctag acttccaaga gctgtaagtt ctgccattga gattccggca 18420 gtaacagatg cgtggtacag atcacctttg atctggtcaa aacgctctag cataacggct 18480 ttactgtgtt cgctatactt acgggtggtg gtcgactgtg aggcgttcac tgtcatgctc 18540 gtcagaaaca gaacaagcat tagggttaga gtcttcattt cgatcatttc cttaagtttg 18600 gttatacagt ttgtttcagt gacttagagt aacactccta gtgtgtaaca cgataataat 18660 atctgtttga aaaaatatag aaaggttaaa atgacagtta aatcccggta aataccagcg 18720 aggtatttac cggagacagt tacataacat attaaactaa cagtatttat ttaattattg 18780 ctttactatt taccttgact gggatgttca gcccttctat atttagcgca attacgttag 18840 catttgtgaa cataccaaat tggttaacat aatggcttac taagaaagat tgattaattt 18900 tgtccagtct gtattgttca gcgacccaag aacagaacct ccctctatgc agttcatcta 18960 gagctacacc cacctcatcc attatcaatg gcatcccaca gttcttaccg agatattgga 19020 gtataaccca acggaatgca aggttgatca tctcgcgctc gccgccggaa caatcaccaa 19080 cgtctttaat gggtgtgtta ttatcgccag ttattgctgg aaatacgtaa ctaagatcaa 19140 catcgtcgtc agacttacta gttgagcaat tcagtatctg taaacgatta ctccaaatag 19200 gttgtatcac tgcattcata ttagcaatta ctgcaaccaa gaaatcgttc atcaaatacc 19260 cgataagtcc tttaaccggt gacaagccat ccatcagcag taaagtgtgt ttctcacgtt 19320 tctctagttc tttgatatta tcggctatag actgaataac agagttcaaa gattctgctc 19380 gaattaagtt actgataagc tgatctttac gaggagttaa gtcagagata agttgttcta 19440 ctttctgctt tactttgtac ttcccattat tctcaacttt ctcttttaac tcttctacca 19500 gaatgtgtaa ctgatctctt agttgttcgt caccattgat aatatcgatt aactccagat 19560 gttctttaat ctccactttc aatctaccga tagaacgttg agtaatagcc aactctcgtt 19620 ctacatcttc agctcgttga aacagtgcat tgatatcaga actttccaag aagttaattt 19680 gggcttttac ttgaacttgt tctttctcta acaagtcaat ttgtttaact agatcattat 19740 aacgaatagt tcttcttagc aattcaatca aactagtgag atctttctta ccaacttgat 19800 aatgatcaac aatctggtag attacttcag agctctccaa tcgacgtagg aagcgatgga 19860 acccttgcat agacgaatac cagtcttcgt tagcctcaat gtaatctgag agtttctgga 19920 tacgttctgt gaggttctcc tttactctta ctaagtcatt gcatttaact tcaagttctt 19980 taatgttaaa cttctcaaat cctaatttga atttgttatt acaatctgga cattctactg 20040 attcagcttt gttaaagtgt tcaatagagt gattgataga acttatctct ctatcaatat 20100 tactcttctc attagtagcg tgtaccaaat cttgttgagc tttagcaaac acttgactag 20160 tgatatccaa atccctagca cgactaactt gttgtagctg atcaatcagt tcattacaat 20220 aacgataaac tacttcgttc ttataaagtt gattgtcatt aaacaactca tgactaacaa 20280 agtaactttg aacattatcg atttcttgag taaatagctc caaactagtc tcgatcatct 20340 ctagtctaga tttataacca tctaaacttt gagtagaaga atccaaacct tgtagctgag 20400 tagtaacttc ggccagtaca gtggttaact ttagattcat cttttcagaa cgatcaagtt 20460 ccttataacg aaaatccaac tgttcttgat aagtgctctt cggaaatttg attctaacat 20520 cattgctcat taatctagag ataatgttac caatctggtt tttcaaatca ccatattgtt 20580 caaattcaac attagaaaac attccgtgaa ttaacaacgc atttttaatt tgattatcca 20640 tcaaactaat ttctttttgc aactcttctg gagaaaggga agccagttgt ttagctcttg 20700 attcctcaga tactaaacgt tgacgttgtg ttttcagtcc acctttgata gtgcttaagt 20760 tagacttaag cttctcaaat attttcaatg cataacttgt atcgttagga ttgattgaca 20820 tcaaaaagtc tttacgtcta gcagtactta atgtagtaaa gaggtctctt acatccaatc 20880 cactcaaaat gttcttgaca ttgttagtta gcttgaagtg aatctttact aactcctttt 20940 gcaccaatag tgtgttacct tcgttaaggt tcttaccatt gtgaataaac tcgtgatgac 21000 tagatttacc agttgatgat ttgaggatat aagttccgtt ttcattaacc agtctaactt 21060 ccttataacc accttgctcg taacttccgt tatcaggtgg cagaggagaa agttcttgta 21120 gtaatgaggt tttaccaaag ccatttctac ctaagataat gttaaagatt tctttggtat 21180 caagctcaat atacttaact ccctttttat aaagaggaga atagtttttc aaaatcaaac 21240 cagttatcat agattcctct taaggatgtt cgttatgaat gtattagagt gctatggtgt 21300 cgctacagta gctgaggata aagctacaga cactgatgaa gtattggtat atcttccctc 21360 tctatatcca gaagcagatg gagaagtagt agcccaagca gaaaagaaag atgtaacaat 21420 acaatccccg acaggagata ctacctccag ttctggatta agttctaacg ctgtaatgat 21480 gaagtggtta ccttttaata ccaataggat aacagcccct gatgtcagaa aaggtagtaa 21540 agttgtagtc tataagttta aaggtcagaa cttgtttagg tggatgtact ttgggatgga 21600 cggtacgctt cgtctggaga cggttatata cgctttctca gccactccca atgtaaagga 21660 agacgcacca ttaactcctg acaactatta tatcttctta atatcctccc atactaaaaa 21720 aattcaatta ctgacaggca tgggtaacgg tgaaccaacc aactacgcca ttacacttga 21780 tacagggcaa ggtgggttta gtttagtaga tggtgaacag aacatgttca ttctaaactc 21840 tatgaaacat ttctggtcgt tttcaaatca agaaaaatct acctttgcta ttgataagaa 21900 aaagattatt gcttcttgtg aagatgaaat cctatttcat ggtaaagaac atattggttt 21960 gaaagccaaa cgcatcacag cagcatgtga aacgtttgat atgtcagcga cagcttcagc 22020 tactattaaa tccccaacta ttaaactagt gggtgatata aatcatgaag ggaacatgac 22080 tcaatcagga acgctcacca acacggccgg gattagttcc gctggagaca tgaaatccag 22140 tggtgacgtt tctgctggtg atattagtct actcaaacac gttcacagag aacaaggtga 22200 cgggcaagat accagtactg cacattaaac ataaaagtaa ctctctactc ccttaattgg 22260 gagtagagag tttatgttat ttcttaaaga acatgttttt aggagtttta gtccctggtt 22320 taccgtagaa taccggaata gattgaccag cattacctat attgagacgt ttattctcaa 22380 atacagggaa cagtgaattg cgataactgt taggatcgtg ataagtaaac ttaccatcat 22440 tgatgaaacc aacaggaaca caattcaaac taggttcaat attaaaccct ttgttgttat 22500 aacgcccaaa taccttaaac tggttgttac tatctctagt tacaaacagt tcgtcattag 22560 tgggaaaatc actactaaac aaatcaatgg gttgtttaat aactaatgtt tcaccaccaa 22620 tggtaatagc agaacccaac ggatataaag gaatgccttg aactttatct tggactcttc 22680 cattgatcac aacgaagcca tttgacttag taaagaaccc gtagttatta ggtgtcttcc 22740 taaaactaga taagcctttt ttcaacatca caggcgattg ataattaaca tgaacacgat 22800 ggggaatctt acttccatac ttgttcaatg tatcatagtc aatctgataa ccaattgctg 22860 tgctgtaagg gaatatagga tcaatagcgt cgtacttagg tttgaatgtt acttcaccag 22920 tttgcttatt gatctcaatt ctcatctcta cgtagaagtt gttaaatggt gcaacgttaa 22980 gcatgacttc atacttagtt tcccttgcat catccaatac tttcaaagcg tagacatcta 23040 gtccagctaa ttgatcaaaa ccaaacactg aaccagtatc aatatctaaa ctggctttgg 23100 tgttgacatt ggttttactc actgtgatgg aactagcaat agagttatta gcaattacag 23160 ttctaatgtt ctcctgggta gtttgaatac tacagctctt aattacgccg tagtaacaat 23220 ctgttccatc agataacatc tctttactat caagagtttg tacaatccag tacaaattac 23280 cttgcagtaa gaagtactgc ttatagctac tcttccagtc tacaacgtgg ttcttaatcc 23340 agttagtaat ttctacactc aattgaactt cattcacacc agtaattggg tgacgatcag 23400 agttctcatc aagagtgtag tttgtataac cagtaaagtt attccagttg ttgaatacca 23460 gtggagcgat gttcatcgta gcacttgttt catcgttctc aattagcata ctgggaacgt 23520 aagctttacg atcttctacc catttacgac ttaaccgttt aggtccaaca taaccatcag 23580 gttggaccac aggtgtttct gactctacgt ttacaaaggc ccaacgatag ttgttcttcc 23640 aatccctagt ttgagtaaga tacagaactg ttttattagt agtatctact ttaaccggga 23700 tgtgacgtaa gtgatcgccg tagaacatat cgccattgat tacagactgg atgttgtaac 23760 tgtattcggt tggggttgga atcagattgt tctcttgatt aatgaactca agggtggaac 23820 ctacaccatg tcgatagtaa ccaatgtact ggcggttata gaagttataa gacttcatat 23880 gaccaccttg ggtttcgaac accccaccaa tcaccgctgg gtgagtaggt tgttctttta 23940 catccccaga gtacatctta aacaaacctt cggtaaccac ttccagattg tcattaagct 24000 cctgtttaac acggttccaa ctatcacttg tttcaacgtt tacggtagag gtaacagttc 24060 ctgcattatc atcaaaatgt agatccaaat caagataagc atgaacatag ttactcttgt 24120 taaccgtgta ccaacctatg cttaatctaa ctgtagcttt accttccagt cgattgcgcc 24180 aagcaaaaga gaccaattga caacgcgtct tatcaatatg tctgataagt ttaccatatc 24240 cacttacatc gtgttcaatg atatctttaa gtttgatatc taaacctaat gtaccagtat 24300 cccttagctt agaagtaatc ttaccgtgag acggaactaa gaactgttga ccaaacttct 24360 tattggtttt gtagattaac tcatcacctt cagtactctt agtagataac ggataatcac 24420 gttccaacat tgatctgata acaaagtcca gtttgataat aatctcacct tcaacttgac 24480 tttcagaacg aggtccaggc cagaacttgt taattaccat atcaacgagt tctaactcct 24540 ctctactata gatagaagtt ctgctaacag gccacatcgc attcaagcca cggtcaatat 24600 attccatgaa cttattacga tgacgtttta caggatcttt cggataagtg aagtttagtg 24660 ctttatcgaa gaaacgtctg atcggaccgt tataaggatc atcaggaata ggaggtaagt 24720 ccctattaac aataaagtca aatctagaac gattcttttc atcaaacgga tactgggaag 24780 aacgaggcca aacttggttg gcaatgtaat caagcattgg tcgttgatca ataggtaaca 24840 gttcgccaag atccatgtct accagaatgt gatataacat gttttcccta gaagcaaata 24900 ctccaccaaa agctttgtta tttgtttcct cagtatcgaa cacatcaaaa ggtaggtggt 24960 ttctgtttaa tgctcttacc ttttgtactc caccttccag atagtgtact gtagagcgct 25020 caaacaacgc ctcagcgctc ctgagcatct ctccgccacc ttgcccagct aacttatcag 25080 aagtcattgt gacaggtctg gtgcgtcttg gtacaatacc tttctcgtag tatcttactt 25140 tagttccacc ccaaggtgtt tgaactgttt tagcagcttc actactggca tcggaaaaca 25200 cccccacaat aggagagttg ttcatcattg gataaatgaa cattccagct ggtgtgcaaa 25260 actcccagtt agactcacca atgtagttaa caggattagc agaactctgc tctgtatcat 25320 ttctgttaat atggtaagta atctgaggaa cttcaccaaa gatcccgcca gaagcaattg 25380 gaatagcttt agctgggaga taactattgg gatcgatagt tacacgatct ttaacaagat 25440 aacttaaacc ttctggatta cagaacagat cctttcgaag accagaaata tgatcatcga 25500 ttgtacccat agcaaagtta tctttattac ctaatccaac agtttcttta gtttcgccgt 25560 gcaaagcacc tttagcttca ctatgaccta aaattaaact atttagatca ctactaaagg 25620 tattaacttt actttgcatt ctagttttaa aatcagcgat ctgttttagt tgtccagcag 25680 aatcaccttg taacttatca cgttctcgtt ctaccttaat gaaagagttg attaatccac 25740 ctagtggatc tttcttatct tccaatatcg gtaaaggtct gtccttatta acatacataa 25800 agaccaactc ctttaaggaa gaagggaagt gttacctccc ctttcgttat ttacaattag 25860 ctaataagtt ctgacgcttt taggaactgg tattcacctg gttcacttaa cattccttca 25920 gtggcaggaa tgcctgtttc tcgtactcga gtaatcggga atccggaaat agcaattgga 25980 ctataacgtt caatgttact gatgccagtt tcattagtgg taactttagc cactagtagt 26040 tgtgtaccac tagtgaacct aagttgctta gtgatctcgt aagtggcagt agagccattt 26100 aacatacagt ataaatagaa cacagtgttt ttataaacag ttgcaattcc acttaagtta 26160 aacatggtct gttttgcttt cacagagatt ccattaaaca ccacttccat atcggcacct 26220 actctaagca cccaagggta acttggaata ggaattccct cgtcagtttt atctacaacc 26280 ataacttcac tgaaactatt aagatcatca atgtcgttta actggtttac tggtaatccc 26340 atggattcgt aatcacgaag atgattatcc caatgattac tttgtaagta cacgacagat 26400 aaaggtggaa ctacatccag atctaactta ggttcaaaga tagagttagg ccaacaagca 26460 ttaatcgcat tatcgatgat tttcttcatg cgatctctaa ggccctgaga cgatgttaca 26520 gtgatcggac caaatccgac tacccaacta ttagtcatct catctccgtt taaacagaag 26580 ctttctagag accctagagc gatctctttt agatattgtt gctcattgag attagtaaac 26640 gtgttattaa caacatccag tgtcggtttc acccaattag gatctaacgt caatgtatta 26700 gtaacagtgt caaagagata atcaacaaca ataacaaagt acttaccacc ttgtcctgta 26760 ttacagaagt gtggtgcaag aattctcact cttgcttggg ttttgttatt aggattctct 26820 acaatgaaat aagaacgtcg tttagctaga actgaattag taactggcgc gctgtagtta 26880 actaatgagg agagtaactt agttccgtca cctttaacat gattacacaa gttaaaacga 26940 ttctggttag tacgtctgac acgatcaacg ttgtcgtagt tcaaagttac tagagtaggt 27000 acaatggaac tactagcaga acttacttca ctaacaggga atctaaagac cttagttgtc 27060 cagttacgac tacgatcatc ttcaccagtt ccagctggta cgtaattacc taaagcttgt 27120 tcttcactta cttgattagt atttacaaac aaataaatgt aatcaccaat tttagcaaaa 27180 tgagaattag caataaagtc ttctgttcca gttgcattcc tgattaaagt aaaatcaatc 27240 tctttatact tgtgttttct aggatctaaa ctagattgac tgtaagtaat gaatccacgt 27300 ttagcaacac tatcaagtgt aataaggaat tcatcaccag aaccagataa cactgcgtcg 27360 ggagttaacc caactgtagt aaagtgagag tgaacatatt tctcattgga atgtctaaac 27420 ttatctttgt tataacgatt aatgagttta tcattgtgta tgtaataaag accacgagtg 27480 ccaccgtata ctcgttttac caatccaatg atccaaccat tagcctcttt aacaaaaacc 27540 ccattctgat attcagtagt agattccact acaccagagt aaataggagg tggtaggtaa 27600 ataccagttc cgtagaaact catcgggagt tcgttttgaa gtacccaagg atcagtatct 27660 ggttcggtct cttcaattac tctacgtaaa ccataagggg tagaataaag atcactacgt 27720 tcaccatcca aatcctgctg aggatgtgcg gtactaaagt tactcaaatt acctagttca 27780 atatcacttg gttttaaacc gtgtgggtta aggtaatttt gaatatgggt aaacagttga 27840 tctttacgaa ctttatgctg tagatttaat tgggtaaaga tgtcctgctg agtttgttcc 27900 aataaaccat caacagccga gtacttacta cgttcatcag cagtaaaatg tttaaagagt 27960 tcaactagcc caccgaaacc aatcatctca tcagaacttg acatgtccat caggtgatga 28020 gcactgggaa cagtttcagg aacgtttacc acattcttat tgaaatctac aacaccacca 28080 gaaaccccca tgtcttcgaa aagctttaac aagactttac gactaatgac aggacttcct 28140 actttctggt aaataacaac taagttgtgt ttgttgttta ctaaatgcgg ttttaattcg 28200 atatataggg aaacactttt accagttagt tctgttaaat cagtaactgg ttctactggt 28260 tcataatcgt cacctttggt tagaaatgtt ccaccattta agatacgaag agaatcagta 28320 taaaaaggcg cttcctctgg tactatccaa aatccggaaa gagtagaagt atcgacgaga 28380 tcttctttac gataagccga attggatccc gtatagtcaa tgtcgactat atttaaatct 28440 ttcatgggaa cctcagatgt gattagagag tgcgatcaaa agatcgcact ctctaagtaa 28500 ttaaaggtta ttctggtaac aagtcagtcg ctttattaaa gatattacta gcattagtct 28560 gagtgtacac tgattcctta gtagcgagaa ttgcactacc agttctaacg tcggtaatac 28620 ctaatccaac aatcgtaaac ctgtcataac actcaaggaa attaatacca gaagcgttac 28680 aagttaacat tgctactaaa ccattactag ttgtttcctg agtttcaatc tcagtaataa 28740 cgtaattaac agaacctgat ttatagttca aataaacata cagagttttg ttaactggat 28800 tagcaattgt gtcagtaata tcaataactg attcagggat agagtaacgc ttaccaccaa 28860 ctatacacat tggtacagct ttacagtaaa gaacgtattc tccaacaaca gtagacttag 28920 taatcaccgg atctgttaaa tcagacggga atgtaaagat agggagtttt ccactgtcta 28980 acaaccgagc attctgacca gtcatcatag ttgccacttt cgcagcatta taaactgtga 29040 tgtgtcgatc ggtagcttta ccttctactg tctcattcaa gctagctgtt ttgaagttat 29100 ccagtttatc taaaccaatc tgatctttct gtacaccatg agcatctgat ttattcgctt 29160 tatgtctttc taggagttta actgtttgtt gtttaaatcc attgatataa acatctaatt 29220 tctcttcgaa tgactctaac atcattgtaa gattaccttt cccaaggata tctttatcaa 29280 tgagcatttc ccaagcatta atcaaatcag taaagccaaa gatttcataa gtaagatcat 29340 gttggtgaag ttttggatta aaccattcag gtttaccatc aatgttattc cagtcaactg 29400 ttcgatcatc ttcagcaatt gcttttagca tcagaatgat atcgtcattg actttgttaa 29460 agttacctac tacttggtaa ctactatacc attcggtaat ttctggtttg agtagtttaa 29520 caaacaaacc tactggttta gcagtgtatt cggttaactt tgacataatc ccgtagaact 29580 cataatcctc gtcaaggacc attggttcac cggttttgaa atacatctta aaactgttca 29640 tgtaaaacgg agcatattga ggaacaaaga tatcattgtt cttttcttta cttcgtttac 29700 catactcttt tgggataagg ttaaacttag agtttccctc caggtctaac ttataacgag 29760 gtacatctgg agttagcatc atacacgata catccttcta aaagaaaata ccggagatat 29820 tatttccaag taccttgcgc aaatccccga atggcttgct tgagtaagtt gacgtttact 29880 aggagttccg tactatttcc agcaagatca tcaaccgttg ccatcttcca gtcttctagg 29940 ttagttacac cgagtgatgg tagatcagct ttatgagcag attgaagatt agctttgaga 30000 tgttcctcta gaagttgctg aacagctaat gggttctcag tccccgacat tgcgtcaata 30060 taactacgca tgacagtgat catgtcttgg tagttataag tatcggaagc aggatgaggg 30120 tgaggatcta ccggccactc agttgggaga ttaatgatct tatcccaatc ttcacgacgt 30180 ggtgcaatct gggcgttagc tacagcttct aagtacttaa tctcatcaag tacgaagtct 30240 gcaccaatgg ttgagtaatc tagttcaatg ttaatcggac tagagacatt gttaattaca 30300 atcccgccgt ataccagtcg attgtactta ccaatgaaat taccaaatgg gaaaacaaaa 30360 gagtaatcac cagcttctag agacaactcc ctagaactat ccagttgttt aatctttacg 30420 ttacgtgaga ataaaggtga acaacgagga ataataatac ttcctgctgc attagcggga 30480 atgtggtgaa cctcaccttt aatatcatta ctcgctagat cttggaatgg gttccaagga 30540 taaaccaatt gtccttgtag cgccgaggta ttatttgtca tagatgaacc tctgtatcaa 30600 aaggtgaaaa tgcatgtaca attacttata tgcagtggga cgttttaagg attatcaacc 30660 gggatttcac gttgttaata tctcttctta tcctgttgga gatctagaga aactctacag 30720 tgtactttac gttgtagcga cagatactct ttataatacg aagatctgtt taacacttga 30780 tgactatcgg ttaagttttg ctaaaacacc actgatgact attcaagaat ggttaaatac 30840 caaggtagga gatgtgttaa aacaatctcc tttgatacct ggaaaagacc gtaaatttgt 30900 taagctagag cggctattta ctcatggatt ttaccactat ccagcagacc ttaatcttgc 30960 aaaggataga caaaacgacc ttatttctga agcagcacct gacattcgat taactcacta 31020 caagtatact ggtgggatta attacaatga acaggttgat aaagcactct ttaatgtaaa 31080 cggtgttttc tatcggtctg taggacgttc tgacggagtt tatctactgg gtgctggtag 31140 tgactatgtt aagcttaaac gtgatgtaag agcttccgcg ttaagctttg aaaaactggg 31200 taatttaaaa accattccta ttaccaagga taatctcttt gagtatgata gcaatggtgt 31260 aaaaagttgg aaagtaaaac ttgaaaatac agaccttaac aataaaacca tctggatggt 31320 agttaatggt caattgataa ctgatagtga aatggtttat caagtcggtg tagatactgt 31380 catggttaat ctatccgggt ttgatgctgt taagcattat caagtttatc gtgaatttac 31440 tcgtactcca aaactaacaa actttactaa gcttgatcag tataagaaag atgcattaac 31500 tatgcataac tcttttattc tactggttag caaccctaca ttaggaatag aggttgtgcc 31560 attgacaact tttaattatc ctaatgtctt gcacactgag gaacgttttc aacatccgat 31620 tgtgctagat aatgggctgt tccctgttcc atatattaag acgtatggga ttggacagcg 31680 tttgttaaac cacgatgtca gaatctctag atactatcct attcaatcct caggtaatct 31740 ggctggtagt ccatataaca gtatggaaat caaccaaggt gatcctggag tgcttcctag 31800 gggatattta tttaagatct ctggcgtgac gtttgaggca gtatgagatg agtcttattc 31860 caaccccctt gtcgtttctt ggggaagtgg ataaaactaa actactgagt accctaggta 31920 tttgggtaat ggtgttttgt ctcactttct ttttgttctt tagggaagat cctaataaac 31980 taaatcaaga gacggtagat aagttggttg ttgctgttga taagtttgct aaagccactg 32040 atagtattac acaagctgct gttaaacagc gtgagtgggc tgctaacttg gaacaacaac 32100 tgatccttaa taatcgactt cttgaacgag gttacaaagg catctatgag aaatacggat 32160 atgataacac ggctattgac agtcctcttg atgatcttta cgctcgccag ttgctcatcg 32220 caaccgaaag taacagcagc gggaaactac gtggagatga agtcggagtt agcaaagctt 32280 cagctttaca aggatcagct agtagcgcta aaacaaaacc taactgatgt accaagctct 32340 gtttacgttc ctgactggaa gaagcgtgaa tccaggatgg ataaacttaa tcaattcctt 32400 gaacacaatg actgtactaa ggaagtagcg aaagatgctt gttatgcaac tactcgttta 32460 atccttattg caaccactaa ggaattagat gtctctagtg aacaaatcaa tgggttgaat 32520 caagttgtag ataaactcat taaaaatatt gatttgatta tcactagctt gaacgaaaaa 32580 taacttaatg ataagttaac tctcactctc cagttggaga gtgagagtta tgtcttatgt 32640 ttatttactt ggtttaataa cgttagcaag tttttctcta aattgttcta gtttgtttcc 32700 acctgataca ataacaccta atgtgttagc tactctcatg aaactccagg aagttatcat 32760 aggcggtaat acagcaatca gaacttccat atcacctggt aaaactttgc cactcattac 32820 agcttctcta atagtgagag taaagataat actcaccaag cagataacgt gtactgagat 32880 acatccagca acagctctca tcaatacagt agataatccg aagatctctc tttccactgc 32940 aatatctgta tctgttacca atggtgttcc gccaggtatc tttaatggtt tctttggaag 33000 ttcttcttca tgtttctcta cgtttgattc atctacggaa agaacagtcg ccaaaataga 33060 tcttgcattt acaaaatgcc aacttagtaa tgcaggagct gataacatca aagcgatctg 33120 tgtggcactg aaccaaccct ggtttgcact aacactatgc caaatcgtca ttacaaaaat 33180 aagacttgta acacctactg taacacaaga gttaaatcct gctgtagatc ttaatacagc 33240 aggaatccaa tcgtaataag ctggatcatt cttatctgtg atttctttat tgttgtttac 33300 tgtcatttac aatatcccac cctaaatctt tgtagtattg cactgcaata taaagggcca 33360 gaagaattgc atcgttagcg tgttcagtaa gttgatctaa gtcaaatcca tttaaatcta 33420 aaaaaggaca gttctttaat ccaattgtta catcgtcctt agtgctacct ttaaagtctg 33480 ctttaacaat ttgtttggca agtcttggta gtacaagttt aaatggacaa tcagatttat 33540 tcgtcacagt gtggatatta aagtacgaga ctacttcgat aaggcgttta aacgaagcag 33600 gattgattcc taagaagtta tcttcgcaag ctactacatt aggatcaatc atatcaaaga 33660 tgtgagaata gactcttgta agccctttag ctcttacctg atgaggatta tcattctgaa 33720 caccaaactc attattctgg cctagaatag tatcagcata aattagttta aatgatttct 33780 tgttataaac atctaactca agagctgcac accctaagct attagttcct gggtcaatcc 33840 cgagtatttt tatagtcatg tttatctcac agcaagactt aacacctctt taccgttaaa 33900 cgtatcaact tctacaattg ccactagagg agctttacga ttcaactggt attgtgttgg 33960 agttaaggga cctactccaa aatagagtag agagaaagca gcaacactgt taccacgctg 34020 tggattacaa ctccaaccat ctccgatatt atattgattt aataatgtca tgagttgtct 34080 tggaatagat aatccaaatt tcttataatc aaaaggagtg ttctgttcaa cgttacttag 34140 aaacgctaat tctactttag tattaatctg aacagtgaag tgtttattaa tcaatggaaa 34200 ctgacactct ttaggatgga atttatattc caattcatca ctgttcttta cagcttcact 34260 aggaagttgc tctgctcgcc agttagatcc agaatagtta ctccctgatt gggagtaact 34320 gtcctttgga gaaaactgac tgaattgatc agtcataatc actcctactc tttaggtgct 34380 tttttcatac acttcttaca aggctgaaga tacgtacctt gttctacaca agctttagcg 34440 tgttcaatgc caattggcat gtcatgatac caaacttctt taccacaaag tgttaccttt 34500 ggccaaagct tactatctgg ctctttaaca acatgatgta taccattttt atttggcatt 34560 gaatacccct ttatactaaa gcgtcttgag caactaacat aggcagagag ttaccaatat 34620 ggaaatacca aggcatggta gagttagcat tagcatcacg agcccaagct tcagtaatag 34680 tgaaactagt tactgctgaa agaagctctt tatagttaac agtaccgccg gaaccaatct 34740 gaccatcaaa ggtagtttca atcccgtgta ccagatacat ctcattgata gcggctttag 34800 taacgtcgtt aaagagaatg gtacaaacgt tacggatctc attaagatca ctgctgttca 34860 aagagagatc cagtttacca gtgccattgg cataagtgtt ggaaagcgga atactatcgg 34920 tagtgagaag ttcatacgga gtaggggaaa gatcttcttt cttgtactcg taaggatatt 34980 cagtttcatt accagtggtc tcatcacgag taccgatctt aacagacgga tcaaacaact 35040 ggaatccgat tttcttaagg taatacatta cataagtaat ttcaccgatc ttacgaacta 35100 cacgcatccg aaagttttcg cgtatagcgg gatcaatgtc attatcaatg gtacgaatca 35160 agaaaggaat tgggtagaaa gcagcttggt cggtagcttt atgttgataa actttacgac 35220 cttccaaccc attagtatct gcacctactg agcgagaacc gccaataccg ataccgtaat 35280 aacctagact gaaatcctta ccgtgtttca tgccaacaga ttcaacagca agaacatcgt 35340 acttctcatt aagagtagta ttagccggaa cattaaaagg ttgtttacag ttaacagctg 35400 ctgaaactac cgtaccaaat gcagtaggag agatcagttg acttgggagt ttacttttag 35460 tacgaccatt atcaattaca tctaccatga ttaaccctta tagattttaa actgtccaaa 35520 gtgaataagt gtattaggat aaacacttac tgtaaagtag ttgtcaaact cttgaatctt 35580 ttcaatatct tcagaataca aaaacggata cttttcaaac acgtgactta ccacatcacg 35640 ttcatttaaa tcatgtttat tcgttttatc tagtattcca gtgagatatg ctaagttatc 35700 cttttcgtgt ttcacatgtc tgttatcaag tagaagtagg acttcctgtt cttgattagc 35760 caatacatgg aaagaacgac tatcaggata acggtctttt agtcgttgca tctttatcct 35820 taaacagctt ctcgaagcct taacccgaca tttaaatgga atggggagaa atcaggttca 35880 gcctctacgt atttcaaata actattaata ggaatatcac cagaaccaat cgattcgatc 35940 tctaagtgat ctaccatatt accttctggg gaacctcgat actccttagc tgttaaacta 36000 gcttctttag taccctttaa tgcatctagt acaagttgat ctttattatc agactctaat 36060 ccagtttctg aattaggaga ccaaatatca gaatcaacta aatccattaa ctggatttgt 36120 ccttctacct caccttcagt agtagaaccg atgtactgga cagtgtaact ggtgagatct 36180 ctcatcaagt taatcaactg tttctgttga tcggcaattg tcatgaatgc agcattttcc 36240 catccagtta ctttcttcca gatgttccaa gctaattcta aacaatcgtc ttcactgtaa 36300 tcatcgaagt taagttctag tttatttaac caatctttat aacgagtttc attggttaac 36360 ttaacagcac cagtttcgta taaactctct accgcatttt taactctggt gtgagtaaaa 36420 aggtttagta ctctggaata gagtttacga tgatcccact gtttatcaaa gatctctttt 36480 gctttaagga aaaatacatc aggagatatg atccttgaat actcaacagt tactttaaga 36540 atgtcttttg caacatcctc agtaagaata tctttatctc ccaatcccat taatacaagg 36600 tagttaggag gtaggatctt ccttacgtta aagtaagtgt aagctggaat aaactcttga 36660 gtagtttttc tatttctatc tagtaagtaa gcccagagaa tgtaggtatc tttagtagat 36720 aatttaaagt gtgttccagt tctaaagtca acgaaatcgt gattgatttg ataaaaatca 36780 ttagccgtta aataaatcca gtgattatga agaactctca tgatcgtatt tggattacga 36840 tctgtagcat ccaccatggt ggactctagc acctttgtag ggatgtctga gtgtacacca 36900 gtagagatgt cgtactccgc tgttgcgatg ctgtatgact cttcctgtgc gttatcaata 36960 gctactttgt tttccttaac aatcaactca ttaacagtta acatccgact tgataaacca 37020 agtttattct gtaagttaac tggtctagaa atgaacgcag gagtagggat taacttctct 37080 aactggtcag tagtagtttg tagagcctca tgtcttgcta gtggaatgtt tctatgggta 37140 aggataatat ccactaaaga gtcaaaggtt tgcattctac cttgcttacg aagcacccaa 37200 tcgatattac gataaagcca catggtttgt ttgttatcaa gcactgattt ataaatcgga 37260 ctaatgccgt aacttgttaa ctttgaccag atgtggaatt cgtgtgcata acgcgtgcct 37320 tccgcctctt ccctaatcat cagaatagcg gagaccagcg aagcgtataa attaccaagc 37380 aaaatagtta acatcaagtt atctgtatac agatactctg ttttgaaaga tgtcattacc 37440 atggtattaa tatgttcttg caaagcagga atcaattgat attcgttcca aagtacataa 37500 tctttgttat atcttaggat ttggtaatta tttgctggta tggattccga aggtggaatc 37560 gggtttataa taccattaat taaattagac tgagctggat atttttccgt aagtctagtg 37620 tagtagtaac tacctagtct atatgcacgt ttagtggctg gatgaatatc cagattagcc 37680 tttgtaaaat caataacgtc actattatct agtgactgta ctttcatgat ctcatcagtg 37740 ctatgatact cgccattgag gtggagataa taacgccatt tggacttatc tgtcccggag 37800 ttaatcccgt agtactgttc catcaaccgg ttatcaagca atgcgagatc ttcacactta 37860 atcacaatag tacgagcgaa tgcgatcgtc ttttggatat aagcgttaaa ctctacattg 37920 tctagcataa tgtttcctaa gggagaatat aaacgtgagt ggactaccga aaggttttaa 37980 accgattgat cgcgctgctc ttagtaacag gacaaagaac ccctctcctt tggagaaagg 38040 cctccaagca ctgttagtaa gagacaggga acaccgtagc gaaaaacggg tagaagagag 38100 cgctaaagcc cctattcgta aagttaaacg tttatcagaa attatcagta gtaatatcca 38160 agctgcgaat gatcttcgca ctgttacaca ttacatcaaa cgtgctgaac agatctggac 38220 tacactactt cttaaaccaa atggtaatca agatattcta cagtatgaca ccactagttc 38280 tgctgtaaaa aatggtaagt tgcatgacgc acttctacaa agagtagaaa actactttac 38340 agtagaatat ccctttgaag aaatgccagc tcaaattatt aaagacgttc tgtgccgtac 38400 tggttcatat gtcttgttaa accttcctca ttcagcttta gaccatctta ttaatggtta 38460 tgaacttgca ggtaccgaaa gtttcaaaac cgtagcaaca gctcaactga gtcaggttta 38520 tgctgatgaa acttacacta aagttcgtaa catcggtttt attcgtaaaa ctaaaccagc 38580 taacgagcta actggttttg aatctctgta tggtaaactc cctgaagctg ggaccgagta 38640 taacttagtt aatgatgcat taggttggtc tttcaccgat aacgtaaacg tattaaaagt 38700 tggtgaagtt aaacagaaac tcagagcaga tcgcttagca agtttagctg gtcaagaaac 38760 tctgcaaact gtgttgggta atgtctttga gaaaaagaaa catactcgtc ataaagctaa 38820 tgctaataat gtagccattg ctgagaagaa atctttagat caacaattaa ataagttata 38880 tcctaatcgt aactttgctt ataatgaaca tctctctgtt cgtcagagta agttctacac 38940 tggtactggt cgtgggttag gagtcactta ccacgttccc agtgaggcgt gtattccagt 39000 tcatgttaat ggtgagattg gtaaaccatt tggttatatc ctgatggttg atcctaagac 39060 tggcgaatac ctgaaatcta ctagcgatag taagttttat aatacaggcg gaacacaacg 39120 cccagctttt ggttcagtta atgaaatggc taaccatatc cgtcagattg ctcagggtga 39180 agagtgtaat cttgacatgg agtggatggt agaaatgagc tccgctattt tggagaaaga 39240 gttcattgag ggtttcatta atggtgatct ggagaaatcg gtaactgttt cactgagcga 39300 gaataataag aaactattct tatctcgtgc atttaaacag caaggtgtac gttgtgtatt 39360 tgttcctgcc gaatacgtta cttatatagc tgtggacttc tctaacgctg gtattggtcg 39420 ttctttggtt gaagaagcta aacttcacat tactcgtcta gctattctag aaaccgctga 39480 tatattggct aacgttgaga atgccatttc tcactctgaa cttcgtattg gtttagagaa 39540 agaagatgtc aatgctcgta acactgttgc actggtgcga gatgaatact tcgctaataa 39600 cccgactctt cacgatatca tgggttatag caacgttagt attgatgctg tattggatcg 39660 ctttaaagaa cagagtctga ctattaaggt agatgctggt gataacaaac atgttattgc 39720 acctactatc gaaactagtc agatgcaacg tgaacctttg aagactattg acccgtctag 39780 taaagaaggc ttgcttaaca ctattgccgg ttacttctgc ttgaaacgta gttggttgga 39840 agatactggt gaaggtaatg actttgctat tgaagctctt gctgatcaag aactacttcg 39900 taaccaaact gctgaatggt ctcgcttgtt tagtggtttc ttctcagact ttatgaagaa 39960 acacattagg tgtaacgaac cgcttcttac tgatctaatc actattatta aagagaacaa 40020 agctctttat agtaaacccg atcaaactgg ttcccttcat gctcaacgtg attctgaaga 40080 aataaaagaa gaagcgcaag agttagaagt agaaggaact aagaaaggta agaagaaaaa 40140 ggaagaagaa caggaacctg agaacgttga aggcgcaggt gtagaagtta ttactcctga 40200 ggaacaatct caggaaattg atgatgttga aatggtctta cttgacttta tcaataactt 40260 ctttgtggaa cttccttctc cggctatcaa cgagactatt aacaagatcg aagataagat 40320 cgaatctatt aataagcttg tttccgcttg gatagaaatg ggtggtggtg ttaagttcat 40380 tgagaaaaaa gctgaagaac tcaaaataga acctgatgaa cttcttggcc agattaaagc 40440 cgctttgttg caacatgcgt ttgagcgttt taacattcct tctccatttg agatgattct 40500 taataatggt gacggtggtg gtatgttgag tatggtcaat gacattacta acttgcaatg 40560 taacgttatt aagttccttg gtgagtatgt caaaggtcaa gagaaacctc gtaaggaaat 40620 gaagaagctc attgagaaga aagagaaaca aaataccaag tttgatggac cggaagggaa 40680 tgaacttagt gtcgatgaaa ctcaagtaga tccaatgggt ggaggtgatt cattcttaag 40740 tggtgacagt aacgacactg atccatttgc tgaagatgaa ttaccagcag ctgatcctga 40800 tatcgtggta gacgaaaata cctctaatga aaatgatgag gaagaagtag ctcccgagga 40860 taaacttcct gacgaagaat aaaaataact aatctttata cacctaccaa gaaggtaggt 40920 gtataacttt ataaatgctt tgtatttaac taaaagggaa taaagtaaat gaatgttaat 40980 attgataact tagaacatgt ttttacaacc atgaatggtt ttgaatcgct atctaatggc 41040 gattttactt cgccagattc agtttatgct aaaactgtat tgaaattaaa cggggtagat 41100 tttaaaggtc gagaaggttc ggaaagtttc ctgtcttctg ttaaagctgg tgctactaaa 41160 gtttatgaaa tgattaagaa cttcttaaag gccattaggg atttcttttt tggtagtaaa 41220 ggttctaaac aaaccaagac aattgatgat gctgtgaaaa gtactaagag tcaactaact 41280 tttttaacca atgttaaacc agtggaaatt acgggtctaa ctcaagaagc tatggataga 41340 attggaaagc aaatggaacg aattacgaac ctcatggaaa acaaagaggt cgcacttgct 41400 tttgatcatt actataagtt taaagacaca tacacggccg gtcactatga ggctttacta 41460 aaatggtttg atgttgagaa cgtacctggt cctaaagttt cagattcagg tttcaagttt 41520 aaagagatta aagaaattta tgaaaagatt ggtaaggtgg cgtcagaaca taaagttttt 41580 aacgatatta agaccccggc aaccttcata agttctttta aaactatcgc cccgctagta 41640 actcttcagg gactttatca agaaatgcgg aatgtcgcaa cacaaagtct tgctgaagtt 41700 accaaagatc ttgagtataa caatgaaata gcgaagaagt atttgaatga taaagaagaa 41760 gtctttatca aacgtggaaa agaaattgaa aaactgtgta aacacatggt tcaagcttct 41820 aataataata cctctttaat taaacattgt gataaccaaa ttttacaaat tgaatctgga 41880 attagtaaac ttaaaaagat tgttgaagac aataaagaat aaaaaatctt aatttcctac 41940 ctacccaatt gggtaggtag gaaaacttat tatgcgactt ctttctgttc caggtattcc 42000 tgtagtgcat cgttatcaac aatcataaca ggttgttctt ccaccttggt agagaagtga 42060 tctttaacct tgttacccag aacgtttacc gcaggtgcta caactactga tgacaagatc 42120 cccaaggaac cagccatagt agctaccagt gaagtaggta caccttcaac gtctttggct 42180 agtttgtacg ataccccgcc tgccagggct gcagcgctta cagtagcgac gttcgacacc 42240 agatcaaaac gatcttcttt aacctgttcg gtcaggttaa cagccagagc agcggagata 42300 gctacgccag caacgatcca tttgttcgga ctgagattat cagtgttggt agatacggta 42360 ggtgctggag cggacatgtc ggagttcaga ttcagtgcag aagtgttaat aataggcata 42420 attacattcc ttatctagac ttgtggaaaa tatctgaata tggtaaacac ttgtcatgtt 42480 tatacactat agtaatatag gtctgagatt tcttggatct taaaataaca ccaaagctca 42540 tataacgctt tctaatcaat agtaacaagt atcccataca ttctgttgga ttaacataaa 42600 caattgctta aaaagaatta cacgacgaaa tagacctata cctggagtga tccaggtata 42660 ggctttagat ttattcgcga ataactcttt aatctacagt acgaagtaag ataagttcac 42720 ccagaccttt cagtgccgag atgttcataa cagattgatc aaagtcacag tacgtagctg 42780 agcgagtgtg attaccactt ggagtttcaa attccagcaa cacaggaact tgacgtccaa 42840 acaacaactc ggaacgttta cgcgcttctt tcacaatagc aaatactgct ggtgaaagtg 42900 attccatcaa agttacttta tcgttactta caggaccgat ctcttttctc agttgggtaa 42960 tcataacttg gcgtttgaat acgactgact gagcaaactc attagtagct acggctacgg 43020 ctactggatc atctttatct acattcttaa acagttcttc ttcagtttcc tttgctggtt 43080 tgataaattg caaattactc ttcaggaatt cattatcggc tagatttagg aaagcacgaa 43140 gtgactcatg atccttattc ttcagcagtt cacagaaggc atccagatca tcaaatagat 43200 catcaagttt aacaaagaag ttaacaccat cgttttctgc tgggaaacca cgacactcat 43260 tcaaccaacg attaaccaag ttggtcagtt gagcacgcag gaactgttca aacatcgcag 43320 aaccaaactg cttaacttta cgttccagag atttgaacat gtcatagcta ttagagtaat 43380 ccaattcctc tccaataacc aaggtgttaa acatctcgta gaatttcttt gattcaactc 43440 cttcttcaaa tgtaaatggt gcattcagtt cagttgccat aatgaatgca tcaagatgat 43500 tttgcttgtc aaaagtcttc agagaagcat ctaccttagc aaaagcctca ctttcagagt 43560 ttactttaac tacattactg gaagacagga tgttcggttc tttctccaga ggttgcattt 43620 cacccagact aataacttta ttatcacgaa caaagtcatt ggtttcagct ggattagcaa 43680 caaacgagga aacaacttct ccattgtgtt cccacataaa tggaagaaca cgattcgggt 43740 ctgtaagagc gaatctcaat gcatcttctc ctgggatacg taagaatttg atttcagcag 43800 ttccgttagc tacatcaaaa cgacacagtg aaacccattc aaggttaagg tagaacactt 43860 cagatttaac aaatttctta ccagtgttaa cgttggtgaa cttggacatg atatcgatca 43920 tgacctggtt ctcagcaacg taccaaccag tatcaccaat ctgaacgaaa taatcgtcaa 43980 agtggtaatc aaaacgagta tccatagtaa agtacttggt ggatttaact tcacggtcaa 44040 aatcattaac gttatgataa tcttgacgtt gttgaactcg ttcttcctta ctaggggcag 44100 ttgggtatgt gccgtcttca acagaacact tggtacgatt gaagtaatcc atcatcaatt 44160 ggtaaccagc cggatcgatt ccctgattat gatctttaac agtatggtga gaaggagtaa 44220 gatcttgcac agcttgataa ctgttaccga tcaaaccttc aaagttaaat cccattcttg 44280 catcaagcaa gtaattaggg agatcatttt tacgcatggt agctgtcaac tgtccacgtt 44340 cccaggggat tacagaacca gggataaaat cgtatcgtgc tttgatacca tcccagcaac 44400 cttcaatacg acgaaggaga gctttaaagt tctgactgga gttatggaag atagtagaac 44460 cattaggatt cttacaaatc caatccagta actggagacc gcaggttgcg ccaacagcat 44520 ctacaatcat ttcagtaatt acattagcgt tcccgcgaat gttctcaccg ttcattagtc 44580 gcatagccgc aagagcagaa agctgcaaac aactattagc aacaatatga ttgtacaagt 44640 tgttgttact catgatctgg ttataaaaca gttcactagt atcatcaacc aaatgtggag 44700 cattgcgatc caatcgacgg aatagttcca taccttgacg aatggcattg taatacggac 44760 cttgaatacg tctaaatcca tgttgcaaaa ccacaccagc aagttgactt gcttcagcta 44820 atgattgtcc cttaaggatt tcattactct gagcgtcgct aagatcaagg aattggttaa 44880 aagacggatc actaccatta ttaaagttat acagactact agaaccacca ccttgttgat 44940 taaggttagc accacccttt gacaactgga tcagctgacc aagcaactga ttaccttgat 45000 tcatattacc ttggggttgt tgctgattac cttgcggttg gttactgtta ttgttgttaa 45060 acatctggtt attacgacct agaagtgttc cgccgttcat tataatacca ccttatgcgt 45120 tagcgctctc taaacttgag gcgatgattc gttgcttcat acaactgtcg atcttccgga 45180 tggagcgcta cgaatctacc agcaaccaat cttactcgtg gttgtagtag tcctcgtcca 45240 tctggattcg gtttagttgt aaattgataa ctacagacaa agggttgcga cgcatgaatc 45300 ttggatcccg gatgattggg atcgaagtct tctttctttc taccaggacc ttttccaaca 45360 ttagccttgg tttgaagaat cacacccaat ccataatcga taaacggatt atccgttccg 45420 gtttgttcca agcaaacatt attatcacga acactcttgt ctatattaaa cagacggaag 45480 aacgtatcaa tttcgcgatt aatgatcttt ggaatgataa ctgctttatt cctgatttgg 45540 aacttaaagt tgttagcttg gttgatcatg taatccatta ggaattccat agaggagagt 45600 tccttgtgga gcatgtcagc tggatcatac aacttaatca ggttggagta attcaacatg 45660 agataattga gcaagtcata cgtgttcttt acttcaatat caaacttgtt gtacttgtca 45720 atggtaagat catcggcgta ctcctcaaca gacaagaaat gttcgttcat ctgtttcaga 45780 taaatgtcat cttcagtacg ctgcgctaac ttaatagaac aacgaccgat gattaaacgc 45840 caatagttga tatcatccaa tttggtaata tcaagatcat ggttgaatac cccgaacatg 45900 tatagcaaac cagcagtgta ttgcagcgct aggttactaa cttgtccatc tttattctta 45960 ctacgaatag caatcgcagg atcgtccatc aaaggcatac cagctggtct gtcaaaagcc 46020 tttggatgaa tagcgcctgt attactataa atctcccaac catctttctc tttataatgt 46080 tcaagcaaag tgtcaacagt atctaaccga tactcacatt caccatactc ttccatacac 46140 tgagagaaac catatttacc aaacagatac caactcaaca aaggaatagg aatcttggtg 46200 ttggtgatac gacgatcttt acgcgcttga taaaagcggt ttgcgggaag tgtcatattc 46260 attgcattgg tgattgtatt ctcacctgct ttatataccc tgttaaaggt atgtaattcc 46320 ttggttactt tgaacttgta tcccgttaca cgaataaaga tagttttatc tttaccccca 46380 tctacagaag gacctcgttc tgataacacg tactgtaaac catacagtga gttacgagta 46440 taaatatctc catgtcgatt agtgtaaggt aggaacatca aaggttcttt gagttcttga 46500 catacacctg ttacagggtc tttgaagtga tgttttacgc gcacaccata aaaagagttc 46560 ttagcaattt caaactcttt tgttccggaa ctcgttccgt tacctggttt ggtgattgcg 46620 ttataaaact ccagaggagg aactttttcg atcccgtcga aaacatatcc tttttcttct 46680 aacgatctaa acatatttct aaaacagttt tcaagatacg tgacactctt gttcaaatct 46740 ttttcgtgcc atccttcaac cagttccggt gtaaacggtt ctctggtctt ggagatcttt 46800 cttagcaact gcggatccat tgcttctcct ttgtatgtta gtcgtacttg ttatttccat 46860 gctgaactag ttaaatatta ggcaaacgtg aataacccac ttatgagacg tttgatatcc 46920 cctccaaacg gacccatgat tgctctaaac caatccagta tagtattatt gagcctgtta 46980 ccttttaagg tatcaaactc ttctttatgt ttctccttga ctttcttgtg ctcaattatc 47040 aactcttgta attcgagttt tactttctta tgttcagctt ttagtttact gagttcagtt 47100 aacttagctg ccagttcttt attactcgga tcaaagattg catcgtcacg tttacgatgg 47160 atattgcgtt cacgaatcaa cttatcaaaa tcagtagagt tataagcaat aaactcaaaa 47220 ggaccgttgc cagtgctacc tgatttcaaa tatacaccat cttccaattg ggagttagtg 47280 atgactggta attcgtaagt ctgtccgaac acagtagtcc agagagtacc cattttatta 47340 cgtttgtcaa ttactacagc tgttgcgtga agaatatcac tattgctaaa gttacggtcc 47400 tcaatagaca tgtcgtcacc taacttaggt tctggcatct ctttatgaag tgcgtacata 47460 ggaaggaatc ccgatttagc taaaacgtta tctaactctg gaactttaca aaccaatact 47520 cccagtgatt cactaacaaa atagttcttg ttaatatcgt gacaggtatg gaaagcacga 47580 tcccaaggtg ttgcccaatg ttggcaataa ggatgttctt gtttgaattc ggatagatgt 47640 ttacccagtt gttccaacag aaaaggactt tcaccagttt tggtgtcaat cacatctgtt 47700 aatacacaat cgggtactcc tacttcccca tagataatca attgattaac catgaaagga 47760 tctctattca atgtttcact ggtcttagct ggaagaatgg tcttcacgcc agatcgatga 47820 attagataaa gatcttcgaa agtgttgttc tcaataagag aacgaaatcc aaattcagag 47880 tttttatgta ctcgtgaatt gttcatctta ttttctctac tattaataca tcagaaataa 47940 acctccctga cattacaact taataatatc tatctgaaaa aatatagaac aaagaaaata 48000 gaggacaaaa cataactcct actctccttt tgggagagta ggagttttag ttagcgtatt 48060 aacaacttaa ctacattacg tagttattac ggtacagtta cagtaccagc accagccggg 48120 aagttagtta cttctacctt ctggacgccg gcaggattgg tggaaccact gacttgtacc 48180 atgtgcttgt tgacagcact gatcagacct tcgtcactca gcagctgagc aatgtcttcg 48240 atctcggcca gaccagcaac acaactcaga gcgtggtgct gataagcagg ctgggtgatc 48300 agcatacggt actgacgatc agcttgggtt acagcacctt cgataaccag cagttccttg 48360 gtcacacaga tacccatacc accgtagatg tcgatttcgt catctttggt gttggacttc 48420 ggtacaaccc acagcagacc cttctcagag ttgatgttgg tttcaacaac ttcaaacttg 48480 acgttgttac caaaggtacg gtagtcacct gcgttcatca ggaacggagc catggaggag 48540 tgagcgatta cgcgatactc ttcagcacga ccatccagct ctttcaaagc ggctacgttg 48600 gagttcacac gcagagcggt gatgatgtca tagatcttgt taaccaggac agcgcggatg 48660 ttatccagag cgtctttgga atccagagta gacacttgct ccagcagctt gaacttgctg 48720 tgtacagcag tggtgttcag gaagtgctga cccggcagaa cagaggagct atcatcgttg 48780 atgttgacca tctgctgacc gttgttgtca tacagatatg caaagtgacc atgagctgca 48840 cggaatgcgt catgagacat ttcacgagta accagtacat ccatctgctt gatcagctga 48900 gccagtacgt cagcgttggt gtcatcacct tgcatcggat acttaacaga gatcgggtta 48960 cgacgacgta caccgtagtt cttgatggtg ttagcgaaca caacggtggt accgtagcgg 49020 ctctggttaa cgttgttgtg gttcattttc agaacaacac cgtgaacaga agcttctaca 49080 acctgagcag tgatcagagc ttgaatatca gcaggcatac cagcagtacc cgggaccagc 49140 ttctcaccgt tcttcattac ataagcaatg gtaacaggag atacagtcgg ggacagagca 49200 cgggtagaac gctgataggt agcagagtac tcgaactgta cgaagacttg cagaccggca 49260 tcagtcaggg ttttgaacag ttgggtcggc gcaccagctt tggtcttcag gttggcgacg 49320 tccataccgt tgataacgaa agcgatttga cgcttctcat cagaggtcag accggtacca 49380 ggacgcatag cggtagagga catggtagaa gtgtccaggg tagcaaaacc ctcaccatct 49440 ttggttttga tcttcagcag gaagctgttc agacgaatgg aaccggattc gatttcatcg 49500 ttctgttcaa aacgcggagc accaggagct tgacacaggc tcatcaggtt gttagctttg 49560 cggattgcca gatagttggt cttgtgagct tcacgaccca gcaggtcatt agcttcataa 49620 gcttcatccc aaggggtgaa gtcagcttca gcaacgaaag ctgcacggtt cgggttgtta 49680 gcatcggaag gataaaccgg aaccagtttc aggtcatcac ctgaggagaa cttgtcatca 49740 gccagaacag aagcaatcgg gcgcagatct tcgaaagatt cgtttacgtt accagaaacg 49800 ttataagcac caacaccagc tacgtcgatc ggcagttgca ggttttcgtc agcatagccg 49860 atggtaacag ttttgaacag ttcttcagca gcatcccatt gacggttacc acgagcgttc 49920 agttccagag tagcggcttt gtgacggttg atcttaccgg cttccataga agcagagaaa 49980 gattccatac caccgacttt aaccatgtca gcaaatttag cagcacgatc agcaaagctt 50040 tgatcagcaa aagaaccaat agcggaagcc agagcattct tctggttaaa accgataccg 50100 gcattgatgg tggtttcaac agcgttcaga gattcattac cggtaatacc agcccagacg 50160 ttaccttctt tgaattgtac agcctgcagg ttagccatta cgttcttcag gtgagcgcct 50220 ttgttaccag cacccttcac ggaaaattgg atagtcataa agagaaattc ccatttaaaa 50280 agacatgtcg atatcgaaaa caaatatatt tgtttgcgca acaggagtga gttttacgca 50340 taacattcat taaacgtata actatcctta ttaatcacaa agcattacgc aactactttg 50400 gacagaataa acccaggatc aacgaaacca cgttcttcgc acgttttgaa taagtcctta 50460 gagtcacgga aataaaactc tacagaaccc actgcattta gcagggagcg ataaacagca 50520 gtagacagat ctcccggcac ttcagtgaac aaggcgttct tcacaatatt attactattg 50580 aggatgaata cctgaccacc tgctgtgtgg aagtaaaaac gctttcctgt tttaaccttc 50640 ttgtcggaat ttagaacatc ttgatacttt gttttataga ccgtacctgt ccggttaaac 50700 tcaacatttt taatatcacc aagaggtgta taagttgtat tcttaaaacc acagtattgc 50760 ttttccactg ctcgttggta ttccaaccag tccaagcagt cactgtcaac cacattatca 50820 aatttaggca gataaggtag atcaacaagt cgaagcttgt ttgcattcaa aagatcaagg 50880 tcttgttccc ttaggaaata gacgttggtc tcttttaatc cgaatttaac ttgcatatta 50940 gttacctaac agaattttca ccaaggagtt acgcatgaat aacctaattc gtcttgtcaa 51000 aatagcaaca gcaatgtttc aagcttggcg gttgcacgat acagacatga tggatgaatt 51060 gagtttgttg gctgaatcgg ttcctaaaag taaggaaagt cttgttcaac aagataaacg 51120 agtagaagca ctcttacgta aacttttagt ttggataagg gaacaacctg ttgattccaa 51180 catcataaca tctttgtcag tcagtaaagt tggtgaaatt gttattctcg atcccacttt 51240 agagaaactt cttaataata catttaatga tcaatataac gaagaagata gtcggaaact 51300 catttttgag attattaaag aacttcgtga taatgatgtc aagaacaaat ttggttatga 51360 atttaagtcc atggttcgtc cattcttgtt tgatggtgaa gaagatctaa caagagaaga 51420 ctggattaaa attaacgaac ttatctccgc taagatttca gataccgata ataactttga 51480 taaagctgtt gttgaaaaat ccagtagtaa tgaccctaag tctattgcgg ctgtaatcga 51540 tctattgaag attgagacat ctgcggaagg tatcatgaaa actggtttag caggtttgaa 51600 tgaagcactt tatccagact tagggattcg tcgtggtttg ttctacatga tcaacgcttt 51660 gactaaccgc ggtaagtcat ttggtctggc tcatatcttg gcatccgtcc cactttataa 51720 taaacctgta ttgcgtgata aaagtcgtat tccaactgtt tgtttgatgt cagccgagga 51780 ttctcttggt ttgatcttta agcgcatgta cgaacttttt gttactgcta aaaccggggt 51840 taaaccaaac ttctttgaag caactactga tactgttgta gaaacaatca tcagtggatt 51900 taaagacaat ggttgggatt tccagttctt tcgtgtaaac ccgagtcacg ataacatcac 51960 tgagattatg cagcgtgttc gtaacctgga aattcgtgga catgaaataa ttgtaggtgc 52020 gtacgattac ttggctatgg ctgatcttac cggctgtcaa ggtgaatctc gttctgataa 52080 acttcaagac ttgtatcgcc gagctcgtaa cttctttagt tcacgtggtg ctgcattctt 52140 tactcctcac cagttaaacc ctgatgctaa aaagtttatt cgtgaatccg atgatgattc 52200 tgaaatttac tttgcaagag acatcggtgg taagtcaatg actgagggtt ctaccaagct 52260 gaccaacgag gtagatgtag agatcacgtt ccatgtggct aagatgagta atgatgaatg 52320 ttactttact tactatgtag gtaagatgcg tggtgaaggc gctgctgaat cggctcgatt 52380 tggtatatat cctctagacc ctttaaacgg gttagtgcac gatataaact ttgataagaa 52440 gactttcaga aagtcgctat cacatcgcag tgaagctatg ggtggtggtt ctgattttga 52500 cgacatgggt taattaactt tactggccga gtaaaaggat ataaacatga ttgatgtatt 52560 agtaataggt gaacgtgtat ctgccgatgt aattaacact attatggata aaagcacaca 52620 cattgcggtt cgtgattgca ttattgaggg acccggatat ctttctaata ttaattcata 52680 cgttggtatt agcggttgta ggtttgaaga tacagtgttg gtggttaaaa atgatcctag 52740 taaaacgctg gtaacggata ctaaatttaa caattgtggt gtaagaccag ttaatgttgt 52800 ttgtgggtac gcgtatacac accagattac gtgtgatcat agctatggtg ttcattttta 52860 ataattcata ataagctaac tctagaccgt gaggtctaga gttagcaata tgtttattat 52920 tgttctaaat attttttcca cctaccagtc atgtttttca ttttttcaac gagtttagcg 52980 ttataatcaa gacagtgttt taattccctg attagttctt tactgacggt tatggaagta 53040 agtatatcgt acctaacatt aaattcacgt ttccattctt cattagaaac cgttctaccc 53100 ttacaatcct cattacattt ttccagaaac ttagtccagt gttcaagagt tttggtacct 53160 tcttcgttaa actttgcact agctggtaag attttcttaa tatctgattt aattttagtt 53220 agagcttcga cattcatagt aaagaaagtg ttagcttcta tttttgacag ggtgtttgtg 53280 acttctttac ctaataaccc cactttggta acgtggtgaa aatctatatt aggaacattt 53340 aatagttttg caactgataa tgttggacct gtaaaccctc gcttttctac tccaccttcc 53400 cacccattta aaccagtaac atacgtgtcc aattccatcc cgatattaaa caaaggttcg 53460 ccttcaaatt taatttcaga aactttggct ttaaatacat cgtattcact cttcgggatt 53520 ccaaatatta gtgagtccaa ttcctttgtg ttattttcag taattttgat gtcattggaa 53580 acttttgttt tactaccaaa gaagaaatct ctaatagctt taataaagtt cttgatcatt 53640 tcataaactt tctgagcccc agctttcaca gtacttacaa acccttctgt tcctgctcgg 53700 tgtttaaaat ctacaccatt taacttcaat acagttttag cataaacaga atctggagaa 53760 ataagatctc cattagagag agattcaaac ccattcaatg tatcaaacac atgttcaaga 53820 ttatcaatgt taacattcat ttattttatt accctttagc tatgttgctt tatacttttc 53880 ttggcgtttg aggaatagaa gtaatctaca gacacgtttc atgtctggct ctaatccact 53940 ggtaatagga agatgatctt gtcgataacc taacaaagat ccttttctta ctaccatatc 54000 gttaccttca cccatgtact ggtatttaac aggatgtcct ggttccaaat accctacatc 54060 gccattgtgc cattctactt caatgaactc accttcgttc atagcgttct cactcatagg 54120 gagagagacg ttactagttg ggttcaaatc aagtggaatg tactcttgac catttcgtct 54180 atctgacagt ttatactctt ggagagaatc tgctctagta gtaactgctc tacctttggt 54240 ataatgataa ccagtatcac cagcaatagc atccgccatt actatacgct tacctacacc 54300 actgttttgt ttcctcacat cagcgttatc actgtgttca gaataaccag tagagataat 54360 agttaaggcg tcagcggttt taacaaacgt cgtatcaaga gtggggattt tatcctgagg 54420 gacacggata atgtcaatag ggcgataatg tttatcagca agttctgtat taaagagcgg 54480 atagatccac caataacctt gcttataaaa actacctaat cccttagagt aaatcccgta 54540 ctcatcgtga gcttgtaggt aacttggcac atcaattaac cttgtacctt ggggaataag 54600 tatttgtcta tagttattct ggttatcgat gggttggtgt aaatacagac ctttgtattt 54660 taccccactt ggcattttag cttgtttact atatgtctcc atcaccagag gaagcacatc 54720 acctggtttg cacatcatat agttttcaga tacagggata ttcttaagga cgttataacc 54780 cttatcaatt aactgaaact catattcaac catattggtt tcatcaaaag catctaagtt 54840 ggcttgttga gagttattac cttgagcccg aaagtcttta tctcccatag gggaagcgac 54900 aaactctctt atcaccatat ccgattccga atccataata acctggataa ttagatcatc 54960 acgataagga acaacgtgat cgaaataaat acttggctga agtcttaatt taatagctac 55020 cacttctgcc cggttataaa tgaaatctgc tacttctgta aagtgcgtta cacccaaagc 55080 tttaaactgt gctttaggtg ttatcactac cgctttaatc ctggtactat caattagttt 55140 atcagatctc ttttcaacaa taccagcttg ttttaagaaa ccttctattt ggctatttaa 55200 acccataatt aatctcccat ccctgacctg ttcttaagag ccatcagatc acgtaggaga 55260 tcacttgagc tctgggtaat gtgatgggac tgggaaaggt tgttctcttc tctatagacg 55320 gctaggtggc ttataaacga gatattctct tggaactgtt ctccatacat ccaagtacct 55380 ttgatataat ccatcagtgt catgtcagac tgcttagtaa caccgaactt atcattgact 55440 tcttgaatat ggtattcctt ataagcagag aaaacatact tagcaacttt ctcaaggatt 55500 tctaactcat ctaatccagg ggaatcaaat cttgcatagt tacgtttaat ctctaaccaa 55560 tacatgatgt aatcttgaat ggagttataa attcttggaa tatccttcct tggatatctg 55620 aatgctaagt taacgtcatc ttccccaacc attgaaaagg cttgagccat acgcaggata 55680 gaaagtggac gttcgatcac gttatcgtaa gactccattc cgttaatagg tgggttcttt 55740 tctatttgtt taatctgttt caacgtaagg aaagaactct ttggaatgta aacgttaaag 55800 gtttcttcgg taatcgtttt gtaaagactc accaagttct ctctaacgtg attgtagcgt 55860 gttagatcca cttcctatac ctcgtgttag acataagcgc tagacgtcac cagagctgtt 55920 ttacaggctc ctacgtagat accgctcata tacagtttat caaccggttc caaatcccag 55980 aatttctcta gaatatcaac caactctttt ttaccaatgg ttttatcttt gaacatcttc 56040 cagatgaatt gttctatctc cgtaccacca ccctcgtaaa actctttgga gaagtagtac 56100 gggtaatctt caccttccgc ggatggatga ggggtgtaaa caccttgtgg taacaatcca 56160 cctttaaagt cgtaagcttg tcccatagca gatggtttat gaattacaat cactctatcc 56220 attttgctat agtaaacatt gccataacca cgggtattca tcatttcatt tcggttatga 56280 acaaagtaat cttgtttaaa ccgtttagga tgatcaaacc cattgcggta gaacatatcc 56340 cagacagtga gaggttcttg catcttacca gaatctaccc aatagttaac attgagtaat 56400 tcaatcttgt tacgactccc aagtagttta actgggaatg tataagagag gaacttagct 56460 aaataaggat cgtagagata atcattcttt tcgttaggaa taacaatagt gttttcatca 56520 gagaagaaat ggttaccaag gatctcatcc ataatcgcca attggaaatc atagagtttc 56580 ttattaagct gagtatcgtc tttagtaagg acagcgttac cgccagctac agcaatgtct 56640 ttggagtaat aaagatcttc aataacttta ctgtttaagt tattctcaat ctcttctgtt 56700 accacagcaa agagtttagc ttcaaagtaa taacacttat cagcagcaat agagcgaatc 56760 tctggttgtt cggtaagttt gaacaaacca gctcgaccgt ccccaatatc ccgaatgaac 56820 aagtcacctt tgttaggtgt cagatcaaag atcacatatc cggtataagt gagttcagat 56880 tgagcattag tttggtcaaa gttaaaacta ccaataccgt catctaactt aactatgaga 56940 tttctgattc ttttataaga actatatgtc tcaatagagt taggagtgaa agcatgttgt 57000 tcttcgtctg ttccataact acctcgatac cactctacta gcgtaggaga acctgatacg 57060 aatgaaagta aacttgtatg aggtgtgtaa tgagattcta caatggagtg tcgatagact 57120 ttatccattg ctctttcttc ttggacaggt tcagggactt gtccgataac tgtttgagcc 57180 atttgtaacc cttttatcga taagcgataa taccaagacc catcatgtat gatgagaact 57240 cttcgattag ttcaccatca cctacatcaa cattatcgta gatattccac cagtcatctt 57300 taccaccact tccccaatca ggcgggaatg ggtattgtgg gaatagcgta tctataatta 57360 ctttaccgta ctctggatca ttgagtaagt catcaataca accatcatca aataacctaa 57420 tagcagtatc gaagttaaag gtgagccgat agatgttctt taacgttcct ggtctaagaa 57480 gtaccaagtc gccattctct cttaattcaa tgtcagtttc taatacttct acgtcattag 57540 aatagagttt aaagttaagg ggagaactat gtcgcctagt tactttttta tggtatttca 57600 aaatcaaatg gagaaatgtt ggattccatt caaaaccttg aatttgtgtt acatttatta 57660 acacttgttc tgtttgaacg ttttctaggt taatcaatac ttgtaattga ggagagatcc 57720 agttagtggt tggaggtcgc cagttatctt gactaggtaa acagacatac ttgtttacat 57780 tatcttgaag gtaatcaaat accatactag ctaatttaga ctcaaggaaa cgtctagttg 57840 gataactacg tttattgtta tcaaagtcgt ccggcatcca ttctacgttc attggttgtt 57900 gatacacttg gataggataa gttacttccc attcagtatg ttcgttccag tggtaactat 57960 aactccagct aacttcatat tgaccaatat aacgaccttt gttcacttta gcgatttgaa 58020 catcaccgtg atcaattccg ttatcagcca tttgttgttt aaacactaag cagtcgttgt 58080 taccaattaa gttgctaata taatcagtag gcactaaact gttttgtcta aaccatttga 58140 taaagttact gttaactgga tctacagctt tagcattaac tagtcggtta tagatctctt 58200 ggtaacaagc aagtatttcc attgggatag gaaagtgtgt atctagatca aatagtgtat 58260 ttaaatgctc tcctaagatc gctgagcgta tccttcgtct gaatgattca gcagtaactc 58320 tatccttaaa gaacttgttt atggtgattg tgtaacgttt accttcgaat ataggtctaa 58380 tactacttcc ggttaatggg tcttgccata gcaatggtgt agtgacacct ctcattgaat 58440 ctaattcatc attaaatcca gaaggctctg attcaaactc tacaaagatc ttatcgttat 58500 atccaacatc aatggataaa tcacttcctc ttcttccgtt atactcgcca ccaatcaatt 58560 tagaaacttc agcttcacca ttaaagaaga tttggttatt ctgatggaga ttaaagtaac 58620 agagctcttg agctagtgat ttaaacaccg aaggtcttac tgaaattcga tacgtttctg 58680 atgatggtag tttaactgta aacatctcca tccactccta tatggtgttt tcataacatc 58740 tgagtaaaca actctaccta accgtaattg gttaggtaga gtaactttat gtttattcaa 58800 atgtaacaac tgtttcttct tctatgattt ctatctcttt tccattatcg ttaatgatac 58860 tttcttcttt gatctcttct tctaattgaa gagtattctc ctctggagtt aaagaaggat 58920 taggatcatt aactaacgtt aatgcttgtt tatataaata aactccccct atctcaaccg 58980 gattctccaa gtcaactgat tcacttccag atagcaaccc ttccgagtcg tcatccaatg 59040 tattaatccc actgttaaaa ataaaattaa cattaggaag atcattccat tgactagaga 59100 aacgaacaaa gagttcattc ccatcaggaa gtttaaatac aaagagatca gagataccat 59160 cattaactaa accagttact tgaccacgtt gtaacagttc tcgtaagtac tcggtagagt 59220 aactaggaaa ctgtttattc aaagtagtaa ctacttcatt aatgaagtca gaacttaatc 59280 caacatcaga gaagagttta ccagtaggta atgagaagat tctagaaaca agataaaaac 59340 gtaaagtaat taaaggaaat agtttatcaa aggaaacagt agtaagatca cgactactaa 59400 gatagctgtt taaactgtca ccagacgctc ttacacgaca tttgaactct ccgtagtaac 59460 caagactatc agggagtaca ggtaacgtaa tatagcgatc tgtagcgtct agtgagagga 59520 cagtgttgtc attgtaatct gtgccttgta tcagacctaa atcaaactga tcagagatct 59580 gcttataaag atcgttcata gtacaaggcg aagttaaaga gataaatgga ataacttctg 59640 aaagtttacc taaatctact ttatcaatta caatcccgtt ccactgatct cctacttgat 59700 actctacttt gctacgtgta agagattcag agaacattcg aaggaatgta cttccaggag 59760 gaaggagtga gagtacctgc tctttaaagc tcatactgac cccttaacct ttgaattctg 59820 actcaggttt ttctacctta acagaattag cattagaaga gacagcattt aaaacagtaa 59880 caattttatt acgaagactt gcgatcaaac gagattgttt agtttcgtct ttagcttcgt 59940 caacagtttc tttgtgttct gccttagctg cgtctttcac ttcctgcgga gcatcatcag 60000 ctacagtctt tggtgacttc atttcattag ctgctttctc agctttacta atgctttctt 60060 taagcttctt ggtaagttct tcagcggcac cagcagctga cttacggata tcttggtaaa 60120 cagcaccaag ctgtcctaca gtttgtgaat tagcaactct agaaactgat tggttaattt 60180 tatcaataac ttgtttgatg ctagggtgtt catcaagtag cttctgaagc tctactgatt 60240 caccaagacc tttaaagtaa gaagtaggtt ctttaacttt accatctggt acaggagctg 60300 acttatccag ttcagctaaa gcttccacag attcttgtgc tttctcatcg gcagcctgaa 60360 cttgcttctc accttcacca aagaagaact ctttaattcc acggagtgtt tcaatgattg 60420 ctttataggc ggcttcagcg ctctttttaa gcgtttccat ccatgactcg cacccttcgt 60480 acccacgaag cttaagaacg gtcatagcgt agcattcaga gccttgtagg ttagctagtt 60540 ccatctcgtc gtgagaaagg agttgtgaat aaccatctag cacttcttct acgtgatcaa 60600 gatcattaac cagagtgaca ggaagctcag gcgaatcttc aatggactca cagatctggt 60660 caccgtaatc tgggttaagg gttgttacat taatcatttt aacctcattc atattcgttg 60720 gtaaattcaa aaatgaattc tgctgtatgt agactattca ccaatttaag aagattgata 60780 atgttaaaag aagcaaattc atctctacga gtaattaagt cttctaacat gttaaaagta 60840 gtttggatca aattcagtaa ctttgtagtt gtaaatttaa gatcttcgaa tataacacca 60900 ttttctttgt tttctttgta ataatctaac aaaggagtaa agttagggta ttctgcgtaa 60960 gcttgttcca aagtacaact ttcttgaact gaaccttcac tgacctttaa gtacaaactg 61020 tcaaagttgt aatgaaagac ccgtaagtca atatgggaac gttggttctg taataaagta 61080 actgggataa cgaaatcttt attaatccca tctaacaaat gaaatatttc ttttctaatg 61140 ttgaaaagat ctacctctaa tgcatctacc tttacaacag actttaggta taaagcttca 61200 aagatcacca aacattgttt tagttgttta tatcggtcaa tgttaatcat accaaaacct 61260 ttagttgacc agagaaaaga agatgagtac taggaatctc aatagtgaga acattatctt 61320 cttttgttaa tgagatatct ttagctttta acccaaagaa ccctgtaact ttacagaaca 61380 aaacaaagtc atttagaata tcctcaggaa cccctctaaa accttctata acgtcgttct 61440 cttcagttac tgtaacttta ctcatcttag tgttgaaatc gcttagaaca cgattgagtt 61500 cgtctgggta aaagttacct ttaatttgat gattaacttt caggttctta aactgactta 61560 agtcaagttc ttcaccaaat agatcattaa tagagatctt gttaataaca acaccagctg 61620 gtgagctatt atctctaagc agaactttat taccagaagt tttagcaaag tgaactgaat 61680 caacatcaat ttgaagatta ctgtgattaa ctttgtttaa ctgataaata aacaactgtt 61740 tcaagattcg ttcatttatc agattaatat cagcgatcat tccttaatcc ccgcttcaca 61800 aaagtctaaa gaaacatcta ccgcagctgt gacgtactga attgacaaac tacaaagttt 61860 cttattcata cgtaccaacc aacgaagata atccttttga tctttcgtca tctgatagtc 61920 ttgcttcatt tcgtaatgga gaacttcttt ctcaaactta cgatacaatt caccaactgt 61980 tttctgatta gctctgatgt tatctaccaa ctctttaatc ttagcaagag ttttatcaat 62040 catgaaacta gtgggagaga atgtctgtga gcgaagttta acatccatag ttgtatcttc 62100 aaaatagatg tttacacgat cagtgttgtt atcagtactt gcatcaaaac ggaaataacg 62160 attaccagga agaatatcag ttacccaact tgtagtacct tcgacatttt taccattttg 62220 tttcatacct aagccacgaa tcataacagt agtgacatca ctcatagctt ggtgtagatc 62280 aaaggtagat ggattcttag caatctgacc aattaaatct ttgtaaactt gtacagtttt 62340 aaggtagaag ttattaacat cttccaatga tgcataaacc cactgagcgt cgtctgtgac 62400 cttattaggt acaagtagac gcctcatacc agcaggatac ttaacgtctt cctgagttaa 62460 tccaaagcgt ttacgacgcg atcctactcg gtaggaacga ttatccattc taaagagttt 62520 attgttgatt aaagacatta accaacttac tgcatcttta acaaactgaa taagtacatc 62580 gatgccttta cgtaccttag taccgaaccc ttcactacct tgatagttaa taaaactatc 62640 attatcaaga tcaagaacta aagcagtatt attttcttga gtaaaggttt taatcaaaga 62700 ctctaaacca gcgacagttt ctttattctc ttctgttact tcactagtgt ctacagtaac 62760 agatttattc aggaagaagt tcattccttc ttcataaggt ttcattacct cttcgtaaag 62820 attatcctta cttggactct ttacagtagg tacaaattcg ttagccatct tagtactcct 62880 agtagagatc ataaaatcag cgaacaaaca tagagaagag agagccgaag ctctctcttc 62940 tctagtagtt tacttatgta tcaacagagt tgattaaacg tgggcggata cgaagtccaa 63000 ctgagcagcc aggattgcac cagcaatctt cagaccacca gattggatct tcagagcagc 63060 cttggaacca tcacggtact ctttgatcca cttgctgttg tcagcgttgt ggtcggcacc 63120 tacgcgctcc agtttagcaa tagaagcatc acggttggct tccagagctt tacgatccag 63180 tttagcaaac tggagtttct tagcctgagc ttgaacaccg gacagaatct tggtaagagc 63240 acctttatct ttaccagtag cttcgccacc agcttcacca gcaccaagta cgttaacagc 63300 tactttgttc agggcagtac catcgttctg gacggtcaca ctgaaagaac ccttttctac 63360 agaaaccttg taggttacag tatcagcagt tttggcggtt tgggtagaaa tacccagacc 63420 tttcagtgca tccagcgctt ctttgatgtt ggagttcggg ctaccacctt tgtctttgct 63480 aactgctgat tgacacttgt cgattacaga tgccatagta gcagctacat caggtgcggt 63540 accgtcagcc ttcaaccaac cagcggattt tggcagagta atcttctcgg ccagtttctc 63600 tttagcttcg accttaccgg tcagagattt ggcacggttt tccagacctt tgaacttgtt 63660 gaacatacca gcaaagaagt tgatgaaacc attgtacaga tcaacgaaga acttcttaac 63720 agcagcaaca cctttggcag cagtttcctt aaaggactca acaccagcca gagcattcag 63780 agaggcggta gaggcatcag cgaaagattc aacaccgtga acttcggtcg gctgcccgaa 63840 cttagcagaa accttagcag cacgcttata ctgatcatgg aacagagcag cgttaaacgg 63900 agtagcgccg gacagcatgg attccatacc ttctacgact tcttccagtt cttcaacttt 63960 ctcttccaga gcttcgatag ccacttcggc ttctttgatg tcagcttctg cttcagcaac 64020 agcttcacca gcttctgcga tctcggcagc aacttgagct tcaactactg cttcaacagt 64080 agcttcgatc tgttcttcaa cagcaccttc gagggattcg ttaccagtta cggaagcaaa 64140 aatatcatga agagacataa taaaaattcc ttgaatagaa aagacaacgt ttgaatttac 64200 gcgaaacgat ttaattaaat tgtttactaa ggaaggacgt caatgcttcc acataatcgt 64260 caatgtaaag agtgatctta ggtaagaaac cagagtagaa agaaaatacc tttggattac 64320 cttctagtct agattgcata tccctgatca aagaaatgct gatctgacct ttgatctctt 64380 ccaaatggac aaagctctta cccaccacag tattaaactc tttgatgtag ttcatgtagt 64440 gttcattagc tttagtgaca gcattgtaat cgataaccaa agcattaact ttagtcagca 64500 aagagagtac gtcttccttt gcaaaagata cagtaacatc accactgatt gatttaagat 64560 cagcttgttc tactgtaaac ttacaagtgt ctggattaaa cacaaattgt ttcccaccag 64620 caagtacact tgttaggaac atagaatcct gtttaatagt gaacttggga gtaggaaagc 64680 taagctgatc aagtgcttga atagatttaa cagcttcttc agtattctta acagaagaga 64740 aagatttcag taaacctaac tctttctgat aataggtttc taattccaat tggaatttca 64800 gtacatcaga gattacattg tgaagagtaa ctagatcatc ttcaataata tctggggtaa 64860 ctttatcgtt accttctagc gtagtgagtt tacgaacctg actggaagtt agagttgaac 64920 tctctttaat tccgtcattg cgtgttctac tagctaagtt agagagtaga agcttacgtg 64980 ctccgagttg ttgcaaaata gaggtattgg cttgtttaag tgcttgtaca gcaccatcag 65040 ccattttacc tccagcccac tctacaccag tttttacatt agagctaact tttgcaaata 65100 catcagaaag cagggattcg ttccctgcaa tctgaaggtc actcaaaata agcgcttcta 65160 agccctttct cagcgattgc tgattattgg acatcgtaac actccaggtg aacagtaaga 65220 agcgtcagaa ggtgactgga gagcactgtc aagtagttag acacatctgc tctgaataga 65280 ttaactttgt aatcataatc agtggtgagc agagcgtatt gacggacctt accttcatca 65340 tctccacgtt tcaaagtaac caggttatct ttgatctctt ctggattcag atcaagacta 65400 ttatattcat tattaagatt acgaatatat tcaactagtt cttgaacaac tttgagaata 65460 gtgaacatct gactcagagt catagtgttc acattaacac caccagagtc tttacgattt 65520 atagcacgaa gctcaaaccc aatttcagct agaagttctg agtacatgtc gttttcagat 65580 tcaccagtgt aatgatcttt caaccaacga ggtgctacga atttgcaact tactactcgg 65640 ccttccagca taggagctga ttcgctacgg ataaatacat tctcttcttt tggatcgact 65700 ttaccattga agttaagaat ctttggtgca ctaaaggtta cgttgttaag ttcctttagt 65760 ttattgttcc caaaataacg aatgatgtta ccacgataac gaccaagttc catctcacag 65820 agtttcatca cagaagagaa gtagttaact tcttttacta tgtgtttagc aagatcggat 65880 ggaagaggtt cagttccttt ggtcagagcg cgaacaagca atccattaag ttctacttgt 65940 ttcttaccgt cacgttgctg cgtgacagaa tccaacatag aagtaacatt ctctatacga 66000 gtatcgagta cttccaaaga agtggtgagt tcggtataac gacgctcaaa cgtatctgag 66060 agctggttag ccaaacgctt gatgttgcga taagtgtctg ctagaaacga ctctagaccg 66120 gctacacggc ttgctcgcca ctctttagga gtaacagtca aaccaaagct ttccattcca 66180 tcaacagaga tacgaccacc tgctttaact ttcaaaccac cgaactcatt aaccatgtca 66240 tcagtttctt gaaccaactg tggggtgatt tcgtaatcgg ctttttcatt aataacggta 66300 agtgctttct ctacacgatc tttaatagaa atatcggtac ggatatcttc tactaactta 66360 gctgcttctt tttgtagttc agaaacatca ggaactttag ctaaactgat ctcagccatt 66420 tggagttctt gcattacagt atcagccata ataaactcca tcaatgctca aacagaactt 66480 ggcagtgagc tcaggtccaa tagctgcaaa gagatccata acgttacgat tctgaataat 66540 agagaagtcg atatcctcta ctttaaagtt atctttacga gcatcgtact cgtcatagat 66600 aatcggagct tggatctgct taccaggttt gatataagca attttaccca gatcaatttt 66660 catctgagtg gttacattac gaatggaaag attcccacta atgtaaccaa caattgctcg 66720 aacaagatct ttacgagcac cagaacctga acgatagttc acataaagcc aactacggaa 66780 gtcatcgcca atgtactctt tagcaatggt gaaaacttca atatgacttt cagcattatt 66840 aatgaggtta aacccattaa cgcctttgag gaaggatttg agaatttgct catttccttc 66900 catccgctga tctgtgaaac tagcaggaac caacccgaat cttgcgtgtc ggaagtcctt 66960 agccattgta tttccccatg attgcttcga tcttagcgcg tttcttcaag atctcatttt 67020 cataagtctc aatttgacga tcaagtgcag gatcttcagt accggaacgt ttgttattca 67080 aacgagcaat tttcattgcc atcagttcga tctgttcctg agatacttgg atagtagaaa 67140 catcacgacg catcttccac agtcgaatcc agaagagtgg gttcatttcg tgaggagcaa 67200 gaccttgacg aacagaaaca gcttccttac cttcagcttc agcgataatg ccttcggaga 67260 gatcatctac ttgctcatca gaaagagctt cgatagcttc cagcactact ttataacctt 67320 cactgaaacg agtcaggaga ttaccgtagt aagctgcagt atcgttgaag aaagcaaagt 67380 ctactttatt gagcagtgat ttaacgtcag ctttctcatc ccaaccttgt gtcaggagaa 67440 cgtccaaaac catgttggta taacgattaa agaagttaat agctgaaaca gtatcaagaa 67500 caccgcgttc tttaaaggta atggtttcac catcataagt cttagtacta gactgagata 67560 cttgtttacg cagttctggt aatacagaag ctacgttatt aactcccatc tcaattgcac 67620 ccagcaaatc aaagttgtta ccgatcttgg atttaacttt agactgaata cctttaagaa 67680 ccgcattgtg atcaatgtaa gtactcagag tgttataacc acccagtact tccttaaaga 67740 gtttcataga gtctttgaaa ccaaccacgt ggttgagttc acgatcaatg gtcaaaagca 67800 gatctgcttt tgaatagttt ttaatcagaa tcatgtttat cgcccaacaa agagtttcat 67860 gagggaagaa agatccatag agttttcttt cttggtaata actgagatct ctttacgtgt 67920 atattcttcc ttcatattag aacctgagtt ccagaaggta aagataccca tgccatcgtc 67980 aacaataaca atggtgttag caaggacttt cttacgaata gcagcaatac cagatttgtt 68040 aaacttgata ccaagttcca tttcgatctg atccgcagtc tcttggctca tgataatggt 68100 attggccatt gtgttcatgg acataatacc agttttcaaa gcagccatct tgttcttact 68160 agaacgttca gtagcttctt tatagtaacc agacatgtca ttcatacgga tattgaattc 68220 gcgtttgatc tgatcagtgc cggtaaggaa ttcaggagaa gtgagttcgc ctgattggag 68280 catcatgtaa cgaccgaaca gaccttcttc tggacgagct gcttcaaaga tagcttcaag 68340 atcgtttgaa gagacaggaa caggaacttg acggaagtta agggggaagt taaccatggt 68400 ggaaccgatc tgtacagaag cttgtacggt acgaccaagt gccagaggag cgtaagtgcc 68460 aaagtctgga taatctttac cggcgatagt tacacgacct tcaatagcag cttgaggttt 68520 acttggagct tgaccaccaa atgcttccac accttgataa gccaagaacc ctgcacgacg 68580 tggattaatg gaatctacca gagatgcgat cttaataccg tctacttgac cctgcatagc 68640 aaggtgggtc agagcgtctt taatatcacg caagttaatg atggtcatca gatcttgagc 68700 gtattcttga tgaatcaaac tgcgctcaat cgcaaccatc ggagagatca aaacacgccc 68760 agcagactga gaaacacttg ctgtgtttaa aacattgtat gctgaaccta cacggtcaat 68820 aacttctttt gctttgtcga tgttttcccc gcctttacct acaatggtag cgagggaggt 68880 cagcatcgag ccaaacgcca aaactgctgc aatggccata tatactcccg gagtaacaga 68940 tggaacaaaa tgagaatgat tttacaaatt ataccggaga aaccctagat aaacgaaaag 69000 agctttttga tgcagctatg ctcgatagtg gtactccggg ttatactgca ccgctaataa 69060 attctcttcg aggatttagg ctactaggca gaggaccggc tatgatgccg ctgtccgata 69120 acaccatagg attagccttc gtcactcgtc cacaattgaa tttaactgat gataacgtca 69180 gtcgttctga gaagctttgt agtttaatgg gtgtctcgca atacagtatg ggtgcctata 69240 taagagggat gttagatgag cgttgggctg ctgcaaatca acctataatg cttaataacc 69300 agattccttt tattacctgt ttaactgagt atctgaaaac ctctactggg tttggcgatt 69360 tacaaattca aactcagagt tcagaacccg gtattcgtga tcaagtgtat cagcgtgtga 69420 gtagtaagtt agaagagaac ggtacattta ccatggctca gacttactat aacccgaaac 69480 caagtgtaat accagctttg ttccaagtat gggaagatta catttcggaa gttacttctg 69540 gtgaccgtaa cttatctccc agggattttt atctatttgg taatcgtatc gattacgatt 69600 gcagaatcta ccatttgatc atgaacaaag atgctgagtt cttggaacac atctttgcta 69660 ctgtacaatc gatacccaca acgtatccag ctggttcaat ggctaacatt gataataccc 69720 agaactcact tagagcggaa ggtcaagatg acttctctgt ccaatttagt tcagtaggga 69780 tgcggtttaa tgaactgggt ttgattcagt catttaacga acacacctat ctttataacc 69840 cagcattaag accagagaac cgtaataaat attatcggat gttgagcacg aaagagtacc 69900 aagcttataa ttacggagcg atccctttgt tgttacctgt tcaaggtgat aaacgaaatg 69960 attccggtcc tggtagatac gggattaaat taacgtggtg ggtacagaag tgatcacatg 70020 cttaaggaaa taagttatgc tttcttttga cgatttggaa aaatacgcta ataacccaag 70080 cagaattata ggtactgttt tcaaagaaat agaagctaca ttcagtgctg gatcaggaac 70140 actcaatagc aaaggacacc cttttagcta tgcagtggac ttgattgtag gtactaacta 70200 cgggtttatc tcaaggctag gtgataacac tgctaagaaa tatccagtcc atgctcgtaa 70260 tctttctgac ctttctaaag taatgtgtga tgaagactgg tacggtgttt ttagtgaacc 70320 ttctaatctt acttggcgtt ggatagtttc ggaagaagtt attaactcca tcgctttgga 70380 atataccgat accgatggaa cacaagttaa cacttataag aaagtagttc ttcctcctga 70440 tagtcaattc acagtagcag gtatcccttt cttactagag aacccagttg agatccgggt 70500 aatggaccac ggcggttatc aggttgttta tgacagctct tatagctccc ctcttaaacc 70560 attagtaggt aactctcctg atcgagagat cctcaatatt gataatcgta aatatctctc 70620 tgttcattta ccaatgaggc agttagagat tactgaacgt ggtcctgatc ctgttaacgt 70680 tacaactggt tatcgcagta caattgagtt taaagataaa ctgtttgcag taagagcatt 70740 cattacccca gacggttctg ataatcgtta tgaaatgtca gtagttttta ataacgataa 70800 ctttgatcct aatcaaccta ctttgacaat tgatttaatt gatgaaagta gttttgaagc 70860 ttctatccct tctgtgtact tacagaacga aacagcacta ggtcgtatca ctcttcttat 70920 ttacactact aagggtgaat acagtcaaga tctcagtaca ctaaagagcc aagaacacac 70980 agttgggtat tttgattatc gaaataaaca aggtaaattg ggtaagtact ctttaccact 71040 tcgtgacatc aatgaagtga ctgtagatac tattactcca atcagtggtg gtctgaatgg 71100 tgcaacgttc actgagctga agaacatggt gatctatggt catcgtcggc gacaggttcc 71160 tattagtaac tcagacttta ctcaaactct ggaacgtctc ggttacgata gtattaagtc 71220 aattgataca gtgtccggtc gattgtaccg cactactaag gatcttccta ttcaggagaa 71280 taaactcttt gaagacgaat ccatggttcg gtttaatagc tcgattggta ctcataccgg 71340 aacagtactt acttcgctag aagagttgat agcttctggt aacgcaattg acaatggaag 71400 acgcgtaaca gttatccgtg gttctgtgtt tgacattact aatcaaacta accgattact 71460 tcctattcat gaagtggaaa gtttggtcaa tagtaataac cagactaaga tcgatacaat 71520 ggcagctaag tcaatggtct atacaccatt catgtacgtc attgatacca tgaacgatcg 71580 tgctgcggta cgttgttatc gtgtagctaa acctgagatt aaataccaaa cctttagata 71640 tgagaatgct aatctaggta ttcaagttgg gattggtagt attaatatca tctctagtaa 71700 aactggatat actgttaata tcaaaacaaa atcaagtgac gcgtataaag aactctctga 71760 tgacacagta agtattcaac tgatgtttaa aacagctggt tctaatacac ccgcgaccat 71820 gaaaggaaaa ctattaggtc gtactgaaga taaagagcgt atctttagtt ttgacttagg 71880 ttccaatttt gatattgacg ataataacct tattgatttg aaagggttta aacagttcgg 71940 taaacctcaa gatgagatca gagttaactt agatgaaact gtaaacttca tctttactta 72000 ttctggtgaa ggtcaagtac tcaagtctac agcggatttt aagattgatc agtctttgtt 72060 taccagtcta aacgtagcca tcattgaaac tgaatacaag atctcttttg gtaagaatct 72120 tcgttctctt tacactcgaa ttcgtccggt agtaggttca gctcaatatg ctaaatacac 72180 tgaaaacgtt cctgatgttt acccggatga tgtttataag aaagagaacg gtaagttagt 72240 tattgtggat ggtaaagccg ttctagaaca ccgtaaaggt gaacctagaa tgactaatga 72300 aatacctcct aaacctatct ggaaatatct caaggatcaa acagtatatg atgaatatgg 72360 caagcctgtt atgcttcatc ctagactgat taaatatcat tgggatttca ttgggtttga 72420 ctttaactac ttactcagtc aagatgatta cgacggtact tatgtcggtt tagtagaaga 72480 tttctttgct aacgaagtaa acgatcaatt ggttgaattt aataaacaag ctattgatga 72540 aacacgtatc ttgtttaaac cacgtagtac catgggatac acccagatcg ttattaacga 72600 agggattgag aaaactattc gttctgatat taaacttagt gtcacgtact accttaccga 72660 tgaagggatt actgataatg accttcagaa tgtattgatt accaatacac ataaagtagc 72720 aaatgacgaa gtacgtaaac aaacgttctc cctaagctcc ttaatcactg ctctacgcac 72780 tcctgatatc atagacgtga aagtggtggc gatggcaggg aatgactttg tggacgtaat 72840 cagcaacgtt gacgacacta atggatttag tattagaaag gcacttgatc aaacttccga 72900 tagactgttg actattcgtg aagatattga aattgtgttt aaacgacatt tgaataacta 72960 aacataaaag taactctcta ctccctatta agggagtaga gagtttatgt tatttaatac 73020 ttaataaaag tatcgagata gtctaagaat gtttcaacac tatcaatagt gaattcatca 73080 cttagttcat tgtgatccca atcaactgac caaggggaga ttttatcagg ataagtaaag 73140 tacttagtga taatttcgtc catagagtct gtgagatatg gaacgtgttc agcaggacgt 73200 acttctgacc aagagtcttt actaataggt gctgcaagga aagtgccgaa aacacctttc 73260 agtctagcca atgcacgacg taggtaaact tgacgttcac gagcatcagt gagttctgac 73320 ttatccagtt cagattgaat atgcttaacg tattcacaaa gtttagcaac caactcaatc 73380 ctggtatcca ccagtttact aaccgctgaa gaatcaagat aaagatcacg tagagcatct 73440 ctgaacaatc taacgttcat gtcactctta gctacagtta gccccaaccc aagtttatta 73500 cgaactttgc cgtatactgc tggatactct tgaccacttc cgtcattata agagaacaag 73560 gaatcaacaa actccaagac acctttctta caacgcggtt cactagtgaa ggtttctacg 73620 tactcacgaa acttcttata gttagctgtg agaatacgta gttcattaat tacctttaca 73680 acttcttctt taaccatgtt acaccttcaa gggaacagaa agttgaccca gtagattatt 73740 gatacgcttt ttcacatctg gcatttgaga aatagcacga gtataagtta aaccttcttc 73800 tacccagtta cgaccaggga aaatagagtt aagaatcttc agatcatcag ctaagaaata 73860 agcacctttg tcagccacgt atttatcttc gttgcctggg gtgaaagttt catgtgcttt 73920 aacaatcttc tcaatatcct gagtgacata ggctgctgca atagttctca ttgcggttag 73980 ccatttaaca acgctctgtc ctacagcttt acagtcatta acaatagtca cacacaagga 74040 gagcgcttcg ttgtatttgg aaacacgttg accaaattgt gcgtaatcac taaggataga 74100 gttatactga ggataactag tagcgatcag attaacgaca ccattactat cagcatcgag 74160 gatgactttg aaatcatcaa gagcagaggg atctagctta atgttatcag cttgagccat 74220 gattggtgta taactatctg aaagcttttg atacatacca agtacttcca ggttaacatt 74280 ggtcttggtg cgttctaaag cgttcttaag ctgatcctga gcttgcttga aaccaccctc 74340 caaaccaaag ccttcgatct ggacaccaaa taccttttca gaaagggttt gagcaatatt 74400 gatgcagttc tcaggattaa gagtgtccgt tacttcatga ttcaaaccag ctacgaagtt 74460 tacaatatca ccttcagtaa catctttatt cttaacttta gttttcagat cgcgcatcag 74520 catttggaaa cggttcttaa cagtccgtga tttttgcatg gacttgttaa tttcagcgat 74580 cgctttggga acttcatcaa cagctctcgt catccgatta atggcatctt cagctttctc 74640 accacgttgc ttaatgatga tcatagcttc tttgccagta acaccttctg gaagtgattt 74700 gacaaattcg tcaaatgaaa tagtgccaat cccagcgcca ttcccaaagg tatctttaat 74760 caggttctga agacgtggtt taacatcatt ctcaaagtta gtaacagcag cagctgtttc 74820 tttctctgtc ttagcaaacc caaacatggt ttttacttta accacacacc agctaaccac 74880 ttgcttaata aagtcagcaa tggctttcat aatcgccatg aaccctttct tgaaaccttc 74940 aataaaagat tcaccaccct tacgagcatt catccgatca tagataggaa ggagactttc 75000 catgccggag attttcaaac aagtcaagga atcccgatga agacgattat gtttaaaata 75060 ctcttgagca cttttgacga taatgttgat tgattcttgg ccggtgactt catagacatc 75120 atctaaagag attaatggtt cgtcatccgt actgacttta ccagaggtta gttgaacagt 75180 ttgagcgtgg ggggaaagtt ggataacaga tcccaattcg atttcatctt ccatcacttt 75240 ctccttagca gtattcttca acccaagtct tatacttctc actagcttca accaacaaag 75300 cgtttaccag atcagtataa gaagccatct cagtaagttt cttaccttca gggagctcag 75360 gtgcagtagt aacaggaacc tgaataactt ccatttcacc tacattactc agcgctttat 75420 caagtactgc aaagaagtga ataacttcag ataccaccag agagcctgca accggagaag 75480 tttcattcca gtaagaaagt acgtggttac agaacggttt aaaatcttta ccatcaatag 75540 ctgatcgatg cttaagacta atcagagcac gaacataagc ggagcgagta agatcaatct 75600 gaagtttcgg atcggtaatc ccatcagcaa taagggtttt cttaaaagta acaatgtgag 75660 caagatgtga cataattaac tctctttaaa gtagtcagta taaagggcaa gattatggga 75720 aaccaattcg gctgtgtagt gttcaaactc ttgagcttta aaatcggtac cagaacagat 75780 ccacccaatg taacgttgga aagcagttcc ttcgagaata ggtttgttct cttctactaa 75840 cttttcaatc tctctacact tagctaagaa ttgctgttta tcagcaggtt tcattttctt 75900 gttctgggag aactcagtaa cacattcacg caaaatggtt ttaatacggc gataaggggt 75960 atcgtacaca tcacccggca taagccgaga gtgcaaggcg ctgtgcaaat taataatagt 76020 gattaatccc cataaaacag tcgtcagagg tgtcccaacc accagaccag cgccaaacca 76080 tgttggtgta acgattaaag aagttaccgt cataatagag ctgcttaata aagcttgacc 76140 agaagttcct tcagcgtagt agaacccctt ttgaccgatc acaagtgtct ttggacaacc 76200 catcttgata gcatacatat ctgccatcat ttcactacca cggttagaga cacctaatga 76260 caaggttcga cgcaagtctc tgttgttaat agctttatca aagaaggctt gttgggcatc 76320 ttgagattct aaactgttaa ctagtttatc atctacctta gcatcggctt caagatactt 76380 cagagtttct ttgtaaatct cgatcttctc tttagtattt tcagttctcg ccaacatctt 76440 gatagcattg ctttgcatta atacatctgt actagttcgc cagatgttat aaaaggcatt 76500 ccaggcgtga cctagttcat gtagaataaa catagcaaaa gcttcggcaa tacttacctg 76560 tttgttaatt ttttccacat caacaaacca ctctagataa cgttctacgt gaatgtcaaa 76620 ctcgatttta ctaaagtcac caccaaccat accggtcttg ggatcacacc agcctttcag 76680 tacgtctaca ttcaaacatt taaatgcttg agatacctta gagtgtttag tgctgagaaa 76740 cccgtctgta ccttgccgat tcataacaga gtttggtgaa acataaccag tatctattgc 76800 tagatcaccg ctatcaccat gatgttcaat gatcctgact ttgatacctg tcatctccat 76860 gatcattttt actagatcgt cttgctcact cttgatccag tcgatcatcc aaccgaattc 76920 attcttaata atcaatggct taaaaaattc aaccagcttc aggtagcgat cctgtttctg 76980 gaaatccata aattccatac cagccaagga gaagtttaaa tcttgctcct ttctgataaa 77040 ttcgatacct aacatatcta ctcccaggga ataattaatt agcacaggtt ctatatttta 77100 gagaacccta atttgacgtc ataacattcg ggacacccag caatggaaga gaacaaaatt 77160 gtcgcgcgtg tttgcaaaca cgcctacctt tcttttaatc aatacgattc taattcagat 77220 ctactcacag ctaaaattac tgatatttat gctgacggat ctcgtaaaag tagattagct 77280 aaaatagaaa actataaacg tgatttctat atagttaaac ctaaacaccg taatttcaaa 77340 gataagaaag attacataga gatttccaaa tgtgataagt acacttctaa tgaagctaga 77400 ctcgccacta acatctctaa agtactattc ggacgaccag atcgttcagc gcaactttat 77460 gatctaaaat ccaacccttt cgtattcgga tgtcaagaaa ctgtcccagt agtttataaa 77520 cagaagtatt acgataagtt ccctgatcat caaccgcaag aagcttattc cgtagccgcc 77580 tatgacgtag aaacattcat catgccagac aacaccactg gcccagtttg tatggcttct 77640 actacctttg aaaaagttgt ttattggtcg ggattacgtt ctatattcca tgggcactct 77700 gatgaactca tccttaaaac ccttaaggaa tatgaagaga aatacctaaa ggaatatatc 77760 gaaaaacatg atgtcaaaat ccattatatt ttagaagata ccccaggtaa agtagtgtat 77820 aacaatattc agttctggca cagacaagga ccggatttta ttgtatcctg gaacgctggc 77880 tttgatatgg aagctaacca gaatgcactg cttaatgaga actttaactt aaaagaagtt 77940 tactctgatc cttcagttcc aggtgtttat caagattact ttttcttccc aggaagacag 78000 tttaaaacca aagtagatgg atctaaaact ccacttgata accatgagaa gttcccagta 78060 gtccaagctc cagctaagtg gcagtggttt gacggaatgt ctttctacgc tattaaacgc 78120 gcacctcaag gtaaacgcga gtcttattcc ctgcaagcta cctcacaaca cgagaaagtg 78180 gaaggtaaac tctatacgga gattggtgga cacttacaag ctggttctgc tgagtggcac 78240 aaatggatgc tcaagaacga accatactta tatgcgatgt acaacattcg agataactgg 78300 gtaattgaag acattaatag agtaactaat gactactcgc tgtctttgcc atctctagtg 78360 acatcttccg agttgaaatc gtatcaatct caaccaagta tgatttctga taagctctct 78420 ttcatagcgc ttgaaaatgg ttatgtatgg ggaacagtag gacgtcagaa agaggatgag 78480 ttcaaatcta ttaaaccaga ccttcgagat tggatcgctc tactccacgc agagcttaac 78540 gaagagaatg ggaaaacaat ctatgccgga ttaccgtcat ggaagagtaa aggaaggcac 78600 agcgtagacg atatagatgt agccgctgca tatccatcca caacaattgc gttgaatgtt 78660 tctaataaga caacaaggtt ggaggtttgt cagatagaag gtttggatag aatggattat 78720 cgtaaggtag ggattaatta cgcttctagt ccacaggcta atgctgtaga attatgtaac 78780 gtaatttatg gaatgcccgc tatttcagat atttctaact tctataccaa cactgttaaa 78840 ccttttgttg aacaagaaaa agaagccgca taataactct acctacccgc tttgggtagg 78900 tagagtttta ctctatgtta taaagtatca tatatctctc tatctaatcc tcttggataa 78960 ttggaagctt cttcctgtgt gatatacttc cataataccc ctttgtaaac tttattacgt 79020 ttggcagaac ctgagacata agcttgccca aatccgttct cggatatatg tttacttccg 79080 tacaaacaga aatgatgacc tttatactcg ccatcttgta ccacacctaa agctggttta 79140 actttaggat cagataacga ggtattggct ttaagaaatt ccataaatcc atccggagtt 79200 ccttgcgaat acattacagc atcttcttta gatatcacct cccaagtaca accggcgata 79260 gcgcgatact taccttctgt ttgattcctc acgctggaac gtgaaatccc ctccttttca 79320 aatgctgctg tacctgcaag tacaaactgt tgacctttat aaggtccctc cataatgatt 79380 gtggcaagat atggaatagt attagggtct gacaagcctg atagttggga acctatttct 79440 acggcatggg tgttattctc agctttggtc atccattcta aattaataaa gttattattc 79500 tctttaactc catccttgtg gttagcttca agtttccaat acggaatatc tttaaggtgt 79560 tcatatttag gaataaaagt ggtaacaata gctcgatgtg tttggaacat tcggtattta 79620 tcgttaccca tgttaatgtt cttctcttta tacccctcat catgtttagt ccgagcgagg 79680 gtccagacat catctttgag ttgataatag ttacctttag tatctattac gtacttatca 79740 atgatgtaat gaatatcagt tctaccatgc cagtattcca aatagtcata agctacaaac 79800 tcaggatctt tctctaattg ttcttgaatg taatcgtatc ttttctgaac acgatcttca 79860 taatctttca attcaaggga taaaccaagt atttcagtta atgttttaat agacattgtt 79920 atttaccttt agatatttat taactcactt ctccttaatt ggagaagtga gttaggttag 79980 gttattaaga aagatcttca atctttaact taaggctcga aatctctgct gagagttcgt 80040 caatgacgtt gtgaagaaga atgttctctt gctcaggtgt tagggttaga ccaacctttg 80100 tcatcttctc agagagttct aagaactgtt taagagtttc gctctctggg tgtaagtctg 80160 tatgatggaa aggtttcttt tccttttgca acaaactaga tatcggtgat gtctttagtt 80220 cagtgctaca agacctaaac cctgagttaa taagtagttg tggtaaataa gtcctgctat 80280 tgatctgtgt gtaaattaaa gggtgtgtct catagtcgtt tatatacgca ttaataaact 80340 ctcttctttc cccagttaaa ataccatccg taattttggt tattttaatc gctgcatttt 80400 ctttatattc ctgttttatt ttatctatta cttccgactc aatgtagtta taacagtaaa 80460 aacttccagc cttaacaccg tataaaataa gatcaagtgc caccacctcg ggggatttaa 80520 agtgggtcgg ttcgtcttta ccaatgtttt cacaataatg aataatcgct ttaactgggt 80580 taccgaacac gtattcttct ttaaagtgtt tccatgttga tgaaaacaca gccatgtgat 80640 tataagaaac ccaacgattg gatttatctt cttcttttat ttcaagataa gagtttagta 80700 tttcggaaat cgtttcgatc ccctggaaac agttctttgc ctttactagt gcaatggagt 80760 gacttccaaa tttttctagt actatttcgt gggtttgtaa cagtttacac aggtaaacaa 80820 aatcttcatt attgtaagta ttacgatttt gaactggaga agtcatgatt ggtttcctta 80880 cttactaatg cggttaataa aacgattaaa gagttgatta gtagattcta ccatctcttt 80940 cttaaactct tctaatagtt cttgaacttc ctggttggtg taagtttctt tgtgcaaaga 81000 ccacttcggc aattcgacaa ttgggacatt tacttgaact gtttcaaagt cgatcaaccc 81060 tgtaggtgtg aaactgtttc tgattacatt aagagctgag aataaatctt tagagacgta 81120 gttggttttg taatcaacac agtctggaat agaaatatca gaagctttaa acaagtactt 81180 agtaacaagt tccttcttgt taggaacata aattaccaaa aagcggaatg tcaaagtttc 81240 accaaatcca aattcgatat actctttatc tactaaagac tgaagataat taaatctcgc 81300 agttgaataa ggagaaggtg aaccagatgc ttctaacgga ttaactcctt tatcccaggt 81360 aagtagaatt ccaccagcgg taaagaagac tttagtgaaa gctccattag caaaacgagt 81420 taacatttct tttatttcta gtttcataaa taaaaaatcc tttatagtaa aagaaactcc 81480 cttccctact aaagagaagg aagttaataa ttaaccgagg actttgacca gttcctcaag 81540 gaacttacat ttttgttctg ctgttagttt aagttcatat ttagcaagaa tcttctcaac 81600 agttttgaga tcttcttcta catctacaat aggctcaggt ttgactggga ttgcacttag 81660 tttaacatta ccagaaagtt catccaagag ttttcttata ctaccgatgg taggaatgtt 81720 gatagtaatc tttttcagag gaaatggtgg tgtagtatga ttactggtta taaaaaccgc 81780 tggattattc atacagtggt gagtgaagac ctcttgatca tgatttagtg tatacgaaca 81840 taagggtaga ggatcactaa ctaacacttt aacaccggtg tacattttaa gttttgattc 81900 atagtgttct ttactgtact caaaacacca taaggttcca aggttattgc tattgtggga 81960 gagtaatgtc attgagatca acttctcctt tggattaatt gttacatctt caacggtcat 82020 ttcgtcaccc aggatattaa tctcatgctc cacaagttca ccttttaatt gtaaagcagt 82080 cattgtatca aattctacgt tacagaaaag ttcttttgcg gtagtgacat tcttggtatt 82140 attgtactca gtgcatcgta accttctcat gaatacatta acccaataac tatccataag 82200 tacaaatggg ataaacataa aacagacgtc actttctata ctagtgatag gtttagactt 82260 ttgaagatac tcgtcaaagt ttgacttatg atttagttca actagatcgt acttattgtc 82320 tagcaattcc ttaacgtttg ttttgaaacg ttctacagat tctttacgta ggtaaataac 82380 acccagtact tcttctttgg gttctaagta agacaaacgt aaaataacaa ctgggttcaa 82440 ctcggggtaa ttgtagtcca tgattagatt ccttttagat cgtttataat agcttgctgt 82500 tcttcaacaa ttttgcgcag tagttttact tcttgttctg gagaaagttg aagatcggct 82560 tctttaagaa gtttctctat tctttccatt tccgaaatag cctttacttt aaaactatat 82620 acaggtttat cgatcagctt acttgtaaag aaccgattgt ctttagttag taattcataa 82680 atttcaccac cttcatagat tgtctcttgc tcagatgcta acattttcaa acttgggtgg 82740 tcatagctat tcacaccaac tgaaagttta tagataaacc gtagatctgg tgctttacaa 82800 aactctagag gtccagctac taaagcggga agatgtatag gttcggggtc aaaggctaac 82860 gagattaaat gcttagttaa caacacatcg agtttatcaa gatcatcagc taagaaataa 82920 atatccgcac cataaccctt tccatttata taaagtttac ctttacaaac tttattttcc 82980 attttttata ctcctttgaa atacatatat tgtttactac agtctaataa tatcggttta 83040 agaaattata gaaagagtaa aaaatataaa ctattattag ttacctgctc ccagttggga 83100 gcaggtaact ttagatatca catgaaaggc gatgcaagca ttaccagtaa gtcacagact 83160 gtgtagacca cgatcagcca gagagctacc ttaacatgat tctgtttggt aacccctgct 83220 tcgctcaggt actcagggag tttccagttg atcagtttga tcaggtgata aataccgatg 83280 atcagataaa ctgcaactac gatcgcgaca acccagacca acatttcgta aatagacata 83340 attgtattct cctagattta aagtaaagtg ttaaccgatg tactcttgcg cttcttcaga 83400 tttattggga gctacagcgc ccacgatacg tgctgctact tgggtcagac ccaacagccc 83460 cagaccacct attaccgaag cagaaccatt ttggaacccc atgatagctt cgcggttagc 83520 aaagatcaat ccaccaccta ctccagcggc cacactagcg gtagcaacac taccgccttc 83580 acgggtgagt tcgatggcta cagaagcagc cacaccagca agcgcacctg ccagattggt 83640 gaacttgcca agacaagcag tatctttgga tacggctaca gcctcatccc agttattaca 83700 agaggcgtaa cgaagaatag tggaatctgc cggttgggaa ttcagttgac ggaaagattg 83760 atcgaccatt tgctgatgca tggaaacagc ttgggcgtgg agatcttgag cttgattaat 83820 catgttatat tccttctcta tacttaaagg ttgaagagat taaagaatct cttatcttaa 83880 acaagtgaac gataaatcat tcatgtttat acactacagt aatataggtc tgaaaatcta 83940 tggatcttaa atattttgta tttaactagt ttaactaaag gaataaagta aatgaatgtt 84000 aacattgata atcttgaaca tgtattaagc actttgaatg ggtttgaatc tttgagttct 84060 ggtgatcttg aatcaccaga ttctatttat gctaaaacag ttcttaaact caatggtgtt 84120 gattttaaac accgagaagg aactgaagga tttgtaagta ctgtgaaagc aggtgcacag 84180 aaagtttatg aaatgatcaa gaacttcatt aaagctatta gggatttctt ctttggtagt 84240 aaaggatcta aacaaactaa aactattgat gatgcagtta aaagtactca aaacaatagt 84300 aaagaaataa tgagcaaaaa gaatgataaa gattttgatg aagaaaagat gaatacgctt 84360 acagcttata cattggaaaa agaacgtatt gaaaaattaa tgaataatga aaaaattaaa 84420 ttagaaactg acaactacaa tgcttttata caaaagtata atgacgacat ttttacagta 84480 gggttgatag gatcaagatt aaaggacatt cccgggatct ctattactga cttaagagtt 84540 tatgcagacc aactgggaga cttgaatagc agtattgggt tcatagctga aaaacattca 84600 actaaataca catatactga acataatcaa cgcatcagta ttttcgagac cacaccacca 84660 cttgttgaat tacagaaatt gtttaatgaa atgagaactg ttgctacaaa agctttggcg 84720 gatgtcacta aagatcttga acacaataac gaactagcta agaaacaaga aaatagtaac 84780 gatacagagt ccaatcttca ttcagataag gttaaatctt tatgtaagaa aatggtcgcg 84840 gtatcaaata aactaacaaa tctaattgaa tattgcgact ctaaaattat taaagttaaa 84900 cagattatgg aagacgttaa agagctaact tccaaataac gcacataaac cttacctaac 84960 caattaaggt taggtaaggt gatttacgta ttaacggaag caatactctt gcaaattgtc 85020 agctgctttc ttagggaaat agctcagcaa tttacgcata tcaacattag ctacaaaacg 85080 ttgacggttc tgagcgttct tagccaaact taccatgaag gtcatgaact gcttataacg 85140 aaggatttcg tcagcaggtt tcattttctc tttctcaact acgtacagtg gagcaaagat 85200 ctcactttga ccaaactgca cagggttggt aagaatcact tcgataaagt ggttaagtac 85260 cttggctact tcttcggagt caacagagag catctgaacg atagtaccca taaactcaca 85320 ctgatagtta ctacgttctt gcaaactggc agatttaaat tcgcctttga taaactttac 85380 aaagttatca ataccatttt ggtaaattgt agcaggtgtg gtaggaacct tctcagtagg 85440 aaccattaca cttgtatcca tcttctcgac aactgcttgc tgttgagcta cagcagtttt 85500 actttgttcc actacaggcg gtacgtgtgc tttagacata catcaatcct tattctcaag 85560 ttgttttaga agttgttccg catcagggat tcctttgttt ttcttggtca tacggtcagc 85620 tacctcttta gctttacgtt taccaacagc cacagaatca atgatatctt ctaatacgtt 85680 acatggaaga gttaagaaat ctttaagcgg taagatctca ccatattctc taaacccgaa 85740 catctcccca accgcagccg cactgaactg atgactagag tctctgcgag ctcgattata 85800 tttgattgtg ttacttaaag gttctctatc agcaacccaa ccaaacttca tcatgtaagc 85860 tctgcgttct gtaatcaaca attctaattt actttgtggc atgttgcggt aggtttcaaa 85920 gagcagttta tcgctctgct ctttgaacct tggttggagt tgaccagact gatcactact 85980 taggaaagaa tttcctcttg taaagtcacg agatctcgtc gcatcgttat caacatccgg 86040 gtatggtcga aaaaattcag aattggatca ataggagtga aacctccatt aatctccttg 86100 attacatcat tagcacgggt tttgcactta ggacaatgat catcaggaat accgatgtag 86160 acataagtca acttaggtac actcttaatg actttatcca acgcatcacg caacaagtta 86220 tcgtcgctat tgaacatatc aagtagacct tgatcaaacc ctttaggatc ttcctgacga 86280 ctaattactt caggttctcc atcttcgcca ggttccggca aagtaacggt tttatcaaac 86340 cactgaagat attcagccat tcgaatagaa cccatgactt cagcacgttt agttgcgtac 86400 actttctgat tagggaattg cacagcaagt tcacgcaact ctgggttgat ctgttcagcc 86460 atgttatcaa agcaggtaaa gtaatccgcc agataaggtg acttgatatg aacttcacca 86520 gcaccattat cgtgcttaac aacagtgtcg attacattac cttcaaagtc agtgtaaggg 86580 acatctgaag ctttgagttc ttcaatggta aacttcttac cggtgttcag gatagcactg 86640 atttgatcct tatacacttg aggtagacgt atatcatcat aaaccacaag gttagctgga 86700 tcaatcaaat tggtctcgtt ataatcacac ttatcagcca ggcaggagat agtgtaactc 86760 acacccttag gagctgcgtt agcaagaaga gtggttgcaa taataccaac gtcttcaaac 86820 ttgatgatct tgaacagttc ttctgcatca agaatatcgg caacagacca gtaggtcgcg 86880 cgttccaaca tgaaggtcac aaggatacgg gtaatcagtg ctcgttccag atgcatagag 86940 gaaacacgat aacgttcacc gtaaccttta agctctgaag taatcttgtt aatgagcaga 87000 accatatcca atggagtggg aactttcatc ttcaagaaga cgcgggagtt caccaacatc 87060 agtgagaagg tatcaggttc attagcaagt ttaagtttac tacgacgcat acggtcacgt 87120 acagagtctt tagcctttac ttgtggtttg atcgggttga taatcccaat acgttcatta 87180 cggaacggga atgtgttcat tagaactgat ggatcgatga actcttgatt atcttcccga 87240 gctagaaccc gatccaaacc ccgctgatag aactggaagt agtttatcaa cataacccca 87300 agttcatctt gatccacttc aggaaaatgt ttctcttgca gttcttcaaa cttaactcgc 87360 agtgagttac gaatactttc agagatgtta ctattaccac tgttaatgtc atcatcaact 87420 tgtttaagtt gtgcgtacac agtagcggta gtaagaatag cttcgtgttg agaagtcaag 87480 ctaccaagga acaaaggaag agagtaagct tgattggctt ctttaccttg gatgatggct 87540 tctcgcagat attcgatcgg cttaatccgt ttaataggtt tggctggctc ttgggtttga 87600 atttcttctg acattattaa acctcagcag tttcggcttg ttgttgcagt tgacggaact 87660 tattaacacg ttcctgagaa acagtttcca taattaccaa acgtgcatct tgctcggtaa 87720 cttctgggtg agaaacttgg aaatcatgag ctgctttatt gagacggtct tcaataacaa 87780 aactgtgttt ctcaagcgct tcaatttcgg tataaagttg atcagccagg ttctctacat 87840 aaccaccaat atcgagcata tcgatagtga aagattccag atctatttct gccagtttgg 87900 gcagacgcat aacttgacga tcaatctcaa tcagttcatt ggtaacacga tccagatcgc 87960 aagcaaagtc atgtacaaaa gctttctgtt gtaccaaacg ttcagccagc actacataac 88020 taaacagttt gtaaacttcg cctacagctt tacgggaggt tttgatcaat gattgcggat 88080 tgaattcacc ttcactttta ccgccatcaa ggatgtactg gagcgggtca tcaaggttag 88140 aacgagagag agcttgtgcc aatgcagtca gtgcttcgtt accacgagtg ggtctgcgac 88200 caggtagaac cttgacacct ttagcgttac gatcactgcg ttttacttta cttgcagtgt 88260 tacgacgagc acgttttgca gctgcatttt gttgggcctt tttgctcatg ttatgaactc 88320 ctttaataac agaatgggaa catgacttat gtctgagata attgatcttg gagacagaaa 88380 tcttgctgta gaaaatttag gcgagatgtg gcaggatttt gctgcaaggt taatgcctga 88440 agcagctata ttattcaagg atgcgtataa cttaatttct atttctcttc ctgagaatgg 88500 aaatgacatc cagattacta atatcttaat tgatgaatcc cttgaaacat ctgacactgt 88560 tatgcatatc agaaaacttc tgattgacag catagtagat tgtttacaga tgatgggaat 88620 tatcatcgat tacgattatg tttcaccaga tagcttgaaa gatcttgtcc acattctaga 88680 tactatttat actctagacg gtatggatga tttaatgcaa ctggtagaga tcctggatga 88740 cgaattgatc gatgctaaag agcgtttcat tcgtgtcatt gaacgtgttg aaccagatta 88800 tgatttagag aacttccctt atatgattaa ggaggtttct cctaatgtta ccaaaggtat 88860 tctcattggt ttgaatatcc tagataacga tgacactgaa tacatggaac ctaccattaa 88920 acgtcgagta caagctaata aagagtttct caaagaaaca ttagcatggg aacatatcac 88980 gaaaggtggt gcttctacac tctctctcga agtattaatg accttgtttg tttctgatct 89040 tgggattaaa ctcactgagg acaaattaga ttactttaag caagttcttt ccctaatgct 89100 tatctctgat cttactgacg gtcaaatcaa atcccagtat ttcgctttgt tagaagaagt 89160 agcagaaaac atggatgaga tatacaaagc acaaactcta ttggaaaagg ttaaactaga 89220 tgaacaagtt tgattatctc tttgaagcaa ttaataatag agcttacatt cgcaaatcat 89280 ttctactttc agtattctct attgtaactc cttctgtagc taacaataac aagctcaaaa 89340 cagtcccctt tgcgcttcta cgagatcctg acactaaaga agtatacttc cttaaagaag 89400 gtaagaaagt tgttatagag cacgcgcagt acgataaagc tctctttaat aagaacgata 89460 aaatcacagt cgatatgtca gttcatgaat tcgttaaaga gaagattgaa actacagtag 89520 gattgctgtt agtcaactta gtagttttct ttgaatcagt tggacatgca gcaagttaca 89580 tcaatgggcc aattacctct ggtacagtac gaggtctcat cgattctatt atggtggatg 89640 accctaaaga gggtgaaacc attccatctg ataaagcctc tgttacccag tgtcttaata 89700 tcaccaagaa ccttgattac ctagaaggtc ttaatgatgt atttgttaaa gcatcttccc 89760 tagatgttct tacagtacat cctgatgtaa ttaaacttcg tgataaacta ctaaacgaac 89820 tagagaaaga gaacaaactt aatgatgcag ctgctgtagc taaagtcatt gacgaagttg 89880 tagctcttga tgcttctatt caatacaatg gtccgtctaa agacttcttc attgataaga 89940 agtttattga taacgcccgt aagaaaatgt ttgttgtatt tgatatggtt cctgatttca 90000 acactggtaa gtatcagctt cttcgtaact cgttgaatga gggctgggat aaagataact 90060 atccagctta tatcaataca gctatttctg gttcctatga tcgcggtaac gccactggtg 90120 aaggtggcgc agaagttaag gtaatgattc ttcttactga ccgtattgaa gccattgata 90180 ctgattgcca aactccaaga acagaaacag tgacacttaa tgactttagt ttcggatctt 90240 gggtaggtgg ttattataaa accgctgatg gtctaaaggt attaactaag gctgataaag 90300 cactgttagg taaaccactg caatttagag ttccccagtt ctgcgaacaa ggtgacttta 90360 acctttgtaa agtttgctgc ggagaaaagc taggtgctat tcaaaaccgt gtttctgccg 90420 aaacagttct tatcttcacc cacattatgc ttcagagaat gaaaggcatg catagctctc 90480 agttgaaaat ggttaagctt gatttaaata gaatagttaa ataaggatga taacctctac 90540 ctcccagtcc gggaggtaga ggtatttgtt agcctagcaa atatgacttt agttctggtg 90600 taatacctct gggtattttg ctagcttctt cttgagttat gtatttccaa ctacaacctt 90660 tatgtgagtt gagttttcca ttacatacct tagaaacatg ggcttgatca aaaccagagt 90720 ccgttacctc ttttcttccc attagaacaa actgagttcc tttaaactgt ccttctttta 90780 ttacagtagc taggataggt ttaacctctt gtccaactgt tcctttatta gctttgataa 90840 agtaaagcac ttgttcaaag ttttctggaa gcgtagatgt ttgttcttta tcagtacatt 90900 tccaagtaca accaaatgct gtttggagct ctccccggag tacttgataa atagtaacaa 90960 cgtctaatcc actatcgatg atctctttac gtgtattgaa tacgatagtt ttgttcttat 91020 actctccatc cttgataaat gtacctacaa caggataagt aactttaact ttctcagttt 91080 gcttttcctt taaactatga ttaatagctt gttgtttagt tttccaactc aagttattaa 91140 actggttatg ggtaggaaca ccgttaccgt gagaaactgt tagtgtcaaa tatggaatat 91200 cctctaaggt gttatctctt ggtacaaaag tagatgctac tacacgttgc actgctactg 91260 gtttattatc cccattggtg aacttaatct caatacgaag gtatctagct gttagtgttc 91320 caatagaaac agtgaaccct ttggtattaa gtttcttctt agcgatttta cccttagtgg 91380 atacaagggc tttatcactg gaaagtagtt ctggtagatc gtcttgttta ttactataaa 91440 cttgatattc tatccaatcc catccttcat agttaggatc tagttccaat tgctctttaa 91500 cgtaattgta acgctttaga acacgttctt cataactcat agtgccatcg tattgcaaac 91560 ctaagatatc tgtcagaggc ttgtatacat cggttaattc agcatctact gaaacgtaat 91620 tattttcact cattatatgg tccttttgtt tacacctggt agtgatgcat tgggattata 91680 tctgtctgag aaattataga gtagggattt atatcccttt aactataaac gtctggagta 91740 gtaaaaggta ttcttgacaa agaaatcttt ggtcagtaaa tagaaaaagt aaattaaagt 91800 tccctaccta accttgattg gttaggtagg gaacttatgt atgttcaata catattgaaa 91860 gtaaggtata ctcttaatac attacttctc tcttcgtaca gataagagtt tacagtaatg 91920 ctattaaacg ttcccatttc tgagtatata gttgaaacat cagagttaaa gtgatcactg 91980 gtgatgtctt ctgatagttt atttacaatt gagtcaaagg agttagcaaa agcatctgtt 92040 aactcctcat gtgtcataac tgtgtaacta tcgtgctgat taactaattt aaataccgtt 92100 tcagaagtta ttgtgttttc aatactatcc caacctacat cctcaacagt agttaatgtg 92160 tcatcaactc tggctagaag aatatcagga ttaaagatga tgtttaaagc tccctcaaga 92220 gcaataagtg tttgctctga attataacct tcgaagtaat cagaaagatc acaactgtta 92280 agtttaaaca ttacaggagc tggatttgca aatatagcta aaggttccac ggggaatgtt 92340 tggttaattg cgttcattgt ctatactctt ttaattaggt tagttaacga atcagtcttc 92400 atctacgtga aataagattc taccggaagt tggatacaac tcataactaa acttataaaa 92460 ctctaaatta ctaaaacaga ttgattgaaa aacatgatca gaaaataaca actcatgttg 92520 ttcttgtagc tcctctataa tctcattgat tatgtcgata tcgcctggat caatggtttc 92580 tagaatacta tcaaaagcat tggacatgaa acaaaaagaa gaacctcgac aatctaatat 92640 agaagaacca agggaaaata ccaaccattc gtttaaaaca gcttgcggtg taaacactgg 92700 tttatatagt tttggtaata gaaagtgatg acttatcact tctaagttat tttctttaat 92760 tggtgctgga ttaaatgatc tcactgaaat caccattagt aagaaaactg ttacttggct 92820 tatctcctac tatttgacag tattcgaaat aagcttgatt gttactttct atacttgcat 92880 acgtgccatt gatattactc accaaacctt ctctaatgta aagtaagata acaccagggg 92940 aaacatatgg gattatatca gaaagtcctt cagaggtcgt tacaagcgat tctagagtag 93000 ttaactgatg tgttagtata ctttctagtc cagttacagc ttgttgatgt aaagattgga 93060 actgatgttc atccatagtg ttgtcagtga taacttcacc catactgtaa taagcgaggt 93120 ctctattgaa aacacaactc atttcatcgc cgttgttaaa ctgattagct ataatggtca 93180 ttagtccagt tacaatagca tttagaactt cttcgtttct cacattagga agcgagaatg 93240 taatcgtatt aaaattagtt tgcatttctc tcgaccttta ataaagactc taccaagcat 93300 caaagcttgg tagagtcagt ttttatttac attcttacac cgctatcgat aatagaaaac 93360 ttcttacaaa caccttggaa taactctctt cttttccttc cgtactcaac cgttttggga 93420 atgtcactac agacaaagta aacaaagttt ggcatcaggc ctggccacca tttatcaact 93480 ggtctggtac gacacaccat ctggttgtta cgttgtgatg aagatacagc tattggcgag 93540 aataccgtga agagtttggg tatgtctcgt ccagtcccac aacttcctgg tgtagtaacg 93600 acacatctat gttctcgata tgcagtaggg tctttcttgt tagttttgga ggtaaaaaca 93660 attgaatcta aatccggata gtcctgcaat aaccgctcat tgaacttctc gcagaaatct 93720 atcgttccga agaaccagag aaccttttgt tcttctcgat agtcatccaa atagaattgt 93780 ttataagccc ccattaacat ctggtaataa ctttcaaaca actgtggtct ctttaagata 93840 cctgcttcta gcaagttctg actaaagccc ccaaatccct taacattgat acgatgtttg 93900 ttcatatcca ttcgatggaa ataagcaaca acatgcatgt aaggtgtgtg ttctggagat 93960 ctcaagtaac aactaaaggg aaagattgca ttgtaaattt tgtttacaaa ttcgtcatcg 94020 cctttcaacg tacctgacaa cacaaaagta cgtttgtggt taccaaacat caaactacta 94080 taaacagagt aaatcgattc atgtgcttcg tcaataacac ggatcccgca accaagatca 94140 tcgaacactt gatcaagact tggtagagtt tcatcatctc tcattttctt cagatagata 94200 tctatcttag ttaaaggaag aataatgatc ttaggatcta ttacgttatt aacgatagct 94260 tgatgtagtt caggtacgcc aatgatgtca gccactacta catcttcagg tttgatattg 94320 taaaactcac cgaacgcttt aacccagata tcaacgaacc ttggtagaac tgtgataagt 94380 actctttcac ccacatggtg tgctgaaaat aaagcacaga acgtgttgtg agtaactacg 94440 tagttatcgg tgacatacaa gtgatctgga tggtcaatag aaatacattg tgcttcttct 94500 tgactgatct tgaacactga tacaataccg agtttatttt ctacaggact tatgtcccca 94560 gttactgtga aaaatccatc ggtatattta cactcacaaa taccacctaa cgatcttacc 94620 aactcggtaa tgtattcggc gcgactcgcc ataaaggttc gatcttcgac tttaccgtca 94680 attaccaaac agttcatttc caactgatca tttaaatctt cgtattcttc tttggaaggt 94740 ttaaacaatg gtattgaaaa actccctaca tcgccatgta tgatctcttt ggttgttaac 94800 actacccaag tattggatgc agtatcaaag accttccaaa ggtgatctag ggtgcttcta 94860 gctgttctac cgtcggcaaa ggtgaactcg taaatgtctt taactccttg tggatgtata 94920 gaaagaacat taacagttgt accatcccaa gcggtaactt tatcacccgg ttggatatca 94980 cccatcttct tccaaccatt tggaacttta acgagtgatg agagcggttg agcttttccc 95040 ctcccaggcg gaaggttgtt aatagaaaga ggatcttcgt tcatcatgaa ctcgcagaac 95100 tcttcctgtt cttcatctct tggtttaatc tttggattaa gtaaaggcaa tactaccttt 95160 ttaggtttaa tcaccttttc atcttgaata gaaatgcgtg actctttata accagaacta 95220 gtcataagtt taattagttc aggtagcatc gatgaacaga accttaattc tgttttatcg 95280 ttattaaatc tcgcgaacac atgagtaatt tcccacttat gtgttccgta taaatcacct 95340 ggaacctttt ggactcttgc aaagttacgt ttacaaaaag gcattaatat ctgtttaact 95400 aattccggtt tatacccagt gagcctaacg taggtactag ctttataaac ctctaacgtc 95460 tttctcatta ggtatctccc ttagaacaca taaaacgtta tatcatttaa cctcttggaa 95520 agtggtcaca aaagattggt ttctaacgaa ttatgactgc tgtatttatt aacagacctt 95580 tttgtaaacg tagtgagttt ttctcactac gttatttaca ttactgtttc ttaggtggag 95640 gggaagcttc tttatctgta gaatgaggtt ggtacccgcc tcctccgcct ccaggtaatg 95700 ttgaacgttt aggttccttt cgatcaacta gtttcttttg aaatttagag attttatact 95760 ctatttcatc aaagagttta tttacttcct tggatagcga catcttcaaa tcctttcagt 95820 tgaattagga cttctttacc atttacaata gagtgtgaat aatgaagacc tttaccaaaa 95880 tacttttgat aagacctgct agcaatgtgg ataccgcgac ctttaccgac tccaccaaca 95940 acaatgttgt ccatattgct aacggtaatg taatcgtgat cttgatcacc atttttatca 96000 ttaagtctga gaagcttaat attaccagtt tcttctttaa cgccgagaca agaagatgcg 96060 aaagttattt tacctttacg gttattaaat tctgattctg gattatcgga aacgaaatca 96120 acaacccagg aaggtaccag ttgtccagca gtaaagcaat agaacttttt catcattcat 96180 ccttaatatg ttttaacgtt tacactacct ggtttaaatg tctcaggttg aacccaaggt 96240 aatccatcta cttgatctgt tattagtccc tgtgtggaaa gacaagtgag ttccataggg 96300 taaatgtact tatcccaatc tggaaggttg aacatgaaaa ccatatgtcg atagggggtg 96360 cgaatatcgg ctcgttgtac cagacatttc cctttgctat aaataagaac aagatcagtt 96420 cctgctttca ttatagcacg tttcttttta gggacgtgaa cttgatttaa ctttggcatc 96480 aaataaggaa gtaggtcagt tcctgttttg atcagataaa tacgtttcat aactatactc 96540 cagataaacc tacctagaca ctttgtctag gtaggacatt atcacttaat tgcgattgga 96600 ttcatgaagg cttccaatac accactctta cggttcttaa ccaggaaccg atatggctcg 96660 ttgattaagc tctctttctg ataaccgtat accagtgcat tactcattcc accatggata 96720 atggactcgt gtagtgaaac aaacacacgt ttgtctgttt caccaggtaa tccataatcc 96780 aagttattag gatcaatagc tgtacaagcc cagaggaaga tatcggtcat gatgatatta 96840 gcacctttgt acttctcatc aattaccttc caaagagata ctacgtactc accaaagatt 96900 tcaggagtaa tccagtgatc ccaacggttc ttaacttcat caaacttaaa cttgttttct 96960 accctcttac gataggcatc caagtcctcg tttacttgcg gtaactcaaa tgccggttcc 97020 ttagcatcaa accctttcaa agagatctta aaggttttac cctcctcctc tataggttgt 97080 tccaacaagt actctacaag cgctctggtc atccttgcgt cgcgacttgc aacggtagta 97140 gtgatgatag gataatgaac tgctttctta ctctcaaaca tagggttaga aatacttacc 97200 cgcagtttaa ttgtttcata tgttctaaga acacgggaca gatcaatatc ttccaagttt 97260 tccataaact taaagtcgga gaagtcctgc tgtgtttcct tatccaaaat caaatatgga 97320 tcagaatcct cattaaggat ctctttctta aagtagatat aatcaccaga ctcatcacca 97380 gtgatgtaat cagcatctgc acggttaacc acaaaccctt tagcagatgc ggaaccgatc 97440 cggtgtttag tcttaaggat cgactgacca ataggttcag caagagtaga gccgtagaac 97500 aatccaggta ccgctcctct tctggtatat gggttaaacg gtagagccga ttccatttta 97560 ccaaaacaca ctgagcacgg tcttcctgtt ctaccatgtc gacaccaagc aacagaacga 97620 taggtgatct tttctccagt ttcgatctta tccaacgctt taccgatcaa cagttccaaa 97680 gaaccatctt ccaggattcg ccacttacca gccaaagact gtttaaactc cttagagaca 97740 atcttcacaa tcgtccctgt agtgctccca cagtcctttt ggtagtcaat ccctttaact 97800 acctgggcca cgttgtgaat cttcttgtgg aaccactcag agtcctgtag tgcctgtccg 97860 ttagagatca acgagaaacc agcaccttta gagtctgcta gactatcagc aaggttggta 97920 atcccatcag cgtatgattc cataatggta ttaggtagaa tagtaccatt aagatcggtt 97980 acatcaccac gagcaattac taactggaat gactgaacac ttgatactga gcgagtacga 98040 tacaacaacc cgaatactga tttatcaaaa tcaggttcag tcatcatgat ctgttcaaac 98100 tccttagcgc catcagccat acaagtttga ccagattgaa cccgtttctt cagatcagcg 98160 atctttggat ttctcagcac atggagcaca tccatagaac gtgccgatac aacaccatgt 98220 tcagacttta cacacagata gttatgacaa gcgttatgat aaacaaagat cagttgttta 98280 atcatatcgt agaaagcagg atcgtcgttc ttaggcataa tacgacctag gaagttatcc 98340 accggatgct tcagcttatc atcgtcaata aagctctgac gtccttcctt ggacttcaga 98400 acgattacct cgtcaatatg ataaggttcg tcgtggaagt aacgatgggg aatgagtgtg 98460 taccagttga tagctagtaa ccagctatca gtgataactt tctccccttg gtcgtcgatc 98520 acttctactt tataacggcg ttccgtcatg ttgagcattg caacttgatc aagtccagca 98580 aattctctta atctaattgt tttcattgga tcctctttta ctaaactaaa agaacttctt 98640 aatcgtcggt acggtcgcta gaacgttctg ttctaagttt aagaccaaag tcactcatga 98700 tgttatcaat cacttgtagc gaatggttac gacgttcctc acctggttta atcagatgtt 98760 tgatcaagaa tggattatca gcacggataa tacgtttacc ggctaagctt aacaactcag 98820 gactgttagc tagtgccaaa ctacgtacag cagcagctcc gcctttctgg ttaacgaaca 98880 accgaccttc agtttcacca acgttacggt tcaacgtggc tcgatagaag tcacgagaac 98940 gttcgtgttt actaagtgag gttggaagtc caaagatatt aagtttcggc atagattgac 99000 aactaatgtc gtcaccaaac ttgtccaaca tcaagtagta aagtgaactg attacaatcg 99060 ggtgaatggt ggtgatctta gctccattct cattcatgta agtaacagga gttggtttga 99120 tatgagcata agtatcagcc aaacgttcag tgatcttaat ccctatgtca tccgtaccag 99180 aaggtgctag aatcccgaat tcattctcat ctttcataat ccatcttagg tgagccattc 99240 gttcttcagc attcagttgt tctaccaatt ccccaaatga aggattaact gttttgtaga 99300 acagatgtgc tttatcccaa gctgtagcgt aatccttact ttcaaaagct tgtttaatct 99360 ctcggtaaac atattggtta acaaagttca cgtcaagctc gatcaatgag cctaaagttt 99420 gacgacgaaa tgcaggtgtg ttacccacaa tcatatcagc tttattacca tactcatcta 99480 ctggggccat agagtctggt aggattttca tgataacaga tttgttacca tccataccag 99540 tattcttgaa acgcacttta ccttctacat cttccttaag agtaacgata atacgccagt 99600 ccttcagatt gatgttgtga attttacgtt tcaccttatg gaatttacca ttagagtgag 99660 gagtgctgaa atcccttgta atagcaccgc gtgccataaa gatcagattc cacagtttac 99720 ctgacaaagg aacattgtca gcatattgac gttccttatt aacaaaccat ttaacaatat 99780 cgttataata gttgttatat tcttcttcaa tcttttccaa gatcaaagtg tgaggttgag 99840 tgagcttctc agctttacgg ttattagatt ggtttttgta acgttctgtt tgaacttcaa 99900 tatcagctac gatacagttt gggctggagt agaacaatac atcgtaaata ggatctggaa 99960 tcatcaggga gcgtttagtc atcccagaga taccggcatt aggatcctta cgacgaaatc 100020 ccattacaat accatcttcc cgaacacgtt ccccagacag tggacagagt tgtggtttat 100080 cggcactacc gtacaagtta agtggaataa actcttcttc attccactgg aagtcgtgtt 100140 tacggctaaa ggtaacaccg accttacggg cataactttc gaagatcaaa acagcatctt 100200 cttctgtata gacgtgggac atcgcagcta ctttagtttc aataccagga caccattcgt 100260 tactttcaga aatacgagcc gattgtccaa acacagttcc tttacgatat tgactaccag 100320 gtttgatact acggagtaga tcgtcatcgt atttgtactc gaatcccaaa tccatgtttt 100380 gagtattgaa cttatccagt tcaatcacgt catagattcc agtttctaga ttacgaacta 100440 taacgtttac tttaccccaa agattaggct cggtggtatt aaggatatta cgtggaaaga 100500 aaatagcttc aacttccaca tcagactctg cttctacttt gcgagcagtc ttaccatact 100560 caacttcatc accagcacta aactttctat ttgtcggatg ccaaataaca gatgccttcc 100620 ctgcattctt tccaagcata tagagtctgg cagcagatga gttagctcga caggcattca 100680 tgccgacacc gacaccacca gttctaaaat ttacttggtt tttaggtttc ttgtctttca 100740 ttttaaatat ctccctagaa ttacattcta ataatatcgg tctgaaatat tatagggctt 100800 gtaaaaaatt aataaaagga aacttttgtc atgccaattt ctatgaactc tggtaattct 100860 tttttctaca ctgaagaata caaaactatt attcgaagct gtaaagagat ccttttggct 100920 agagcttcat tctctccttt tgtagatgat agtttaagat ttgcttatcg taataacttt 100980 cataaactac ttagaagtat gggaggaatg aatagtctta ttcctgagga tatgatctgg 101040 actatttctt atttaaatgg aatagagaat cctaatcagg acttctccca cttaaaaggt 101100 atttggactg ttactagaga aaacattaac tctgttatcc aagtaactag agtaagaaga 101160 gaaaattaaa tattggttaa atagcctgta agtcagctaa tgctgactta caggactacc 101220 ttattgttgt ttagaagtta tttacactta cagtaccacc tgcaccagtt gcagtgtaag 101280 catccatagg ttgatattga ttgttgttat tcccccaagc gtcattggaa ccaagtggtg 101340 ctgagttata accattgttg ttataaccgt tattaccacc ggcaggaacc atttgaccag 101400 tatatgggtc acgaacaaaa ccaccgccgt taccaccacc catccccatc agaggaggaa 101460 tgccgttgtt ttgcatttga gcaagagcca tgagcaaacg aggatcattc atacctccta 101520 gaggagtgtt acctagtcca ttcatcgcac tcattgcagg gttaattaca atttcattga 101580 taatacggtt atcttcagtt actgatacag aacggatcaa accaccaggc atttggaact 101640 taaactcaaa tacaccatta gactcagtgt agtcacatcc catgtagtgt tcaccagggc 101700 gtgctgtcgg tgcattaggt tgttttacag ctgtattggt ttgttgctgt tggttttgtt 101760 gagtagtgtt accaccgaat agattaaagg tagtaactgc tttactggga gcgcgacttc 101820 ctacattgtc accggatgtg gttacattgt agttattgta atccaaaggc ggaataagac 101880 ctttgtattc acccagtgaa tccaactcag tcaaccagtc cagttcaatg ccataaatac 101940 caatggtatc aaaatcctta cggaatttac tgattaggga attgagttcg ctcaccacca 102000 agccgtaaga gttcaggtat gctgttaaac gtgctgcatc tggagatact accgagtaac 102060 ttgctacagt gttatccaga catgatggga aaaccatctc gaacagataa atcaccaact 102120 ccatggcggc tttacttacg ttgctgttgt tgaagttcaa acgacctgtt tgtttgacat 102180 gatcattttg agctactact cggcatagtt ccaggtaata cgggtaatct gggatagctg 102240 tgtagtaaac atgacgatct tgatcatctt ttccaccttt gatcagattc cagttgataa 102300 gacgattatc aatccccgta ccttccagag taataccaat gcctttgatc agagtaagaa 102360 catcttcttt aacttcttta gaagcattct taaacggctc cagtttctcc aacattttac 102420 cagaagtagt tttaccagtc ttcttaccgg ctacagcgaa cagtacttga gcgataggtt 102480 ggaacacttg gtaaatgcgt gcgcaggtaa gtttgcggat aactttgaag atctcagttt 102540 ccttagacat tactgattca caagcagggt ggaagaatac cttaccaata gtaacaccat 102600 taaggttatc gttagtagga aggtacactt gcttatcttc tactttaact ggaacttctt 102660 gaccagccat attcaggatc agttcgtgat cgggagtgaa acttacaccc caggatttga 102720 gcatggattg gtaaatactg ttaagttggt tcattataaa tccttacatc taaaattagt 102780 agccggtgaa gtattcgtta atgttgctat agaagttagc acccatctgg atcgcggtag 102840 aatcattacc cagaatagag gaagcgttgt taatagcaaa agtcgggaag gtccgagatt 102900 gcatcccaga gactgatcca gcgtcattca tggagaatcc ggttgagatg ttatcttcgg 102960 ttactacaca catattaata gtggtggtac caaagagttc tgcgtggaca tcaaaacgga 103020 tcggagtcag ttggttaata ctgatgccat tgagtttggt gaagatctga ttagtcagtg 103080 cggttacaaa agcttctgct ttagaaccca tgtcaaaatc attatcagtc aatgatgtta 103140 cgttatacgg aagaataaca atgttactca aaccaccatc accaccgaag ttgtcacagt 103200 tagaaccacg gaaagaaatt gtggtcagac cgtacttgat cagtagatcc ataacgttca 103260 tcatgatttc atgactaaca aactcaccga gttgagaagt ccccatactc tcgcaactta 103320 aggagagatc gtccacacgg tattgttcag catcgaacaa ggtaaggtca agtacttcgt 103380 tcaggttatc gaataccatc agtagatcat taatggtata accggtaaag ccagccattc 103440 gaacgttacc aagcattgac gacatttcag caaagaagtt atctcgcatg atagcaggtt 103500 cagtgccacc cacttggtga gctgagtttg ctagttctcc gaataatcct tccccatgac 103560 cttgcacaac tccatccatt tcggtcccgc cctggtatac tctctgtcca cgctgaacag 103620 atagaccagc acccaggatg tcggcagcat aaccggcagg gttcaggtta ccgcgtttgg 103680 acgcaattac acccactcgt gagatattgg aaccagctac agtaccaact ggcgtcatcc 103740 cttccagacc ttcagcttcc atctgatcga tgatggattg ctgagttgca ttattaagtg 103800 cgtactcaac tacatcgcca ggtcgcatgg taaccatttg atcagaagcg gaaccatcat 103860 tcatcaggta atcggtgcgt tgaccgatgg tgcgtttaac agctgttggg gtgtctagca 103920 agccagaacc taccatcctt tcttcacgtt tccaactgaa ctgcggaaca aatatagcat 103980 tcaggtcaag accttgtgag ttgttattat gaatataacc aatcacatgc atatattgga 104040 ccgccactgg agactcctga acaatgaaat ccagcttcat cagacccttg ctatcattcc 104100 aaccattctg gatagtagca aagccagtag cttgggcatt aagtccacct gagagagcag 104160 ccgctgtcaa tagcgaacgt tcatttactc caccttgcag attctcagaa accaaggtat 104220 cgattacctg gttatccatg ttcaccgctg gattacggat tacttgatcg gggtacaggt 104280 tggtcaggcc gacttgagcg ttaactagtt gcattttatt tattcctcgt tttctttttc 104340 tacactatgg gtttgagtaa tcagcgcaag taactcacgt ttaatttctg gtactagatc 104400 aatgggatac atgtcgccag gtgacattgc atcaaggaac ttctgatttc ccaataatcc 104460 tggttcgatg ttagattccc acccagaggc cgctaactca tctaggaagg attgtaccga 104520 catcactaac atgttatctg tactagcagt ggattgaccc acatagatat aacacagatc 104580 gattagatcc tctcgctctt tggtagagag tttgaattca tctcccatgt aagtaatagg 104640 gacagcattt gaacgcatag cacaaactaa ttgagcaaga tgttcataac cttgttcaaa 104700 tagtttaact tgtgccaaac acattgcggc agttagctgt cgataatcca tagcaggata 104760 aagataatag ttaatatcat caataaatgc taactggagt aattgattct gaatgttggt 104820 gaaacgaaaa tcccagacag ttggaagatt atggaacaac ttctccacag ttttctcagc 104880 tttaattcca agagcttttg cttggtgttt aaagatgtct ttataacgag gtttatcttc 104940 ctcatcaaac atcccaaatg agaagaactc tgccatggct tcttcgtcag aaccgtttac 105000 tgtttgagca atacgatagc tttcaggaat ggattgatcg tcactacctg gtttactttc 105060 ggagaaccga gtaaacttag tagattgttc tttacggatc tttccttcta ctaatgagtt 105120 tagctccttg gacaagttct tgtctttgag ctgacttggg ataaaagaca aagagagttt 105180 actaaacagc ccctcgaata cgatataatc tacatatcgt tcttcagata ctacgtcagt 105240 attttcccgt ttactatctt tacgagcaca actggcacga atatacgtat ccatgatttt 105300 ccaaccaggt atctctacga tactagggat ttgagaaatc atgctaccta ctactgcata 105360 ttgatactct ttaccagtta cttcatttat ctgatctaac aactggttaa taagagggaa 105420 acaaagttga gctgtgaaag ctagtttaac caactcagca tacttgtcat tatcaatagt 105480 ggtctcttct ggatagtccc ccatcgccgc catacgcatc aagtctttag gggccacagt 105540 gcgacctgtt acttgcgctg cgtaagcaat ctcattggga gtgaccagct catacatacg 105600 tttgataatc gggcccagct tctcgattag gaactgataa tccaaactac gttcacgaag 105660 ttctgatagt tcgggagttt ctgcttcctc gaaataacct ggttgaagaa ttcgtttacc 105720 ttccttaaac aaattccaca attgatccat tgtactatca cgacaacctt caaagaagat 105780 gttcatgaat tcaaacaact cttggtcagc atcgccaccg caaactgttt gtgttccctt 105840 aaattcaatc tgttcattat tgtgagaaac gacaacagaa tcaatccgtc gtttcccaga 105900 aagtacggtg ctatagcgca ttttaaaaca ctcccctaga ataacactta aataatatct 105960 atctgaaaaa atatagaaca gtaaaaatag atataataga gagaaggctt aaagccttct 106020 ctctttaaat gtgttaaaag ttcttcttag aagtcaatgt catcatcgaa agaagtggga 106080 tctggtttac gttgggaatt gctattccca ccatttccat tccagttatt tccaccgtta 106140 ccaccacggt taccgttcca accgctgttt ccgccagagt tgttattccc accagcgttc 106200 ttgctctcgc gcggtttata accggctatt tctagctcgt taagatatgg tccgtagaaa 106260 ttgataaatg ctttacaata aacacgactc atcaagccag catcttcaca aggttcaccg 106320 tctttggcaa ccataatcat ggaatcaaat ggcgatttga attcaaacat aactttgtag 106380 gaacctttgg tgtaacctac agagatacga ccttcttggc tacgcataac tgtaaaaata 106440 ccaagggtag atggatgttc gttcaaacgc ccacctgcgc cgaaagtaat tttcttgaca 106500 tggtactgag tcttagtaaa gttggtgttg tcgcaagcgt ccttcattag ttcgaataga 106560 gacagccgat ccatggcaga catttcgact tctttcattt tggcattgcg gtcatcttta 106620 ccgaatacgc catcattaac tttgaaatag atcttaccat ccagaccttg ttcccaagtc 106680 cagcgggctg ggtacttagc accgtcgaca ggttcacgtg acattggtgc agggtaacga 106740 tagtcattac acataagttg agggcgacgt tggaaagctt gttgttgaga catgttaata 106800 ttccttttac ttaatcattt tgagtagaat gtcacgttct ggtgcagaac tcggcatccg 106860 tcgaattgta cttgcaataa agcttggtgt cgatgcagta ctccaaggca ctgatttagc 106920 caacgctttg atttcgtttt tcactgagat tgactgggac atgaagttaa cagcgttatc 106980 accaaagatc tgaatagtca gtttgttcaa tgggatatta gttaactctt tccctccggt 107040 tagtttagta taaaactgaa cgtaaccttt tatcgatcca gtgtgtgact ctaatagatg 107100 caacctgtgg taactttctg ttgttactag atcaacaggg tggtgagtaa tgattaaccc 107160 atctcctgag aactgcggaa tacttgaatc cacttgagaa acaaacttat caaactcttt 107220 aataagacgt tttagtacac tattatcaag aatgatcttt ttctttctgt tctcttcttt 107280 tggattaact agtttactag gatcctgttc ctttaattta gctaatggga agagtcttgg 107340 tagagcttga taactcggat aatagaactt aatgtcaagt aatgttttca acttaagttc 107400 agcaatgtaa ttcgcaatcc ctaccacatc atctttagct gcattaaaaa gttcagtttc 107460 gctaggaagc tcctcaaacg cttctctagc gtttctcacc acagtacgta gattgacgag 107520 gagtgtttgg tatctatgca taggggcgct ctggagagct tctatggcca ttgcagtacc 107580 gacacttatc ggtacagtac ctagtgtacg gttaaccatt cattacctcg tctaataact 107640 gttcaaggta cgctttatct atgtcatcgt tctgaccgat agtcggttcc atgaaattaa 107700 acaagttagc tttaaggtta tctttggtca atgtaatagc tttatagtct tctggagaat 107760 acagagtagc atctatatca atattctctt ccttaacatt atcggtttca aaatggtaca 107820 tcggatattg atctttgtac tcatttacta aagctactgt tactgctgat aaaccacctt 107880 taactttaat gcgtgtttta ggtggcggag atttccttaa atagttatca atgatcttgg 107940 taagttgttt aacattagtt tctggagtta tctggatcgt atcgtagatc tgtgcgtaag 108000 tattctcata gaacgaagca ctaaaatgtt ctttgttaaa cgagaacctg taagcaccct 108060 ttggatgcat ttcgccatga gctatacgat caaaagaacc ggaacaatag atgttgtatt 108120 tctgtccagg tttatgaata tgacctgaga agatagcgtg tttagccaac ttactccatt 108180 tcaattcatc gtacagtgta ccgtgcttat tggcaaccgg tggaagctga aatacaaatc 108240 cgccatgtaa gaagataaaa tccacttgag ttaagttatg attagctaat agttcaactg 108300 cttgatcata aatatcttca gtggaagttt taccaaagtt atcaggaaca tacattacat 108360 tgatatctag ttctggaata aactcaatac tcaatgtatt aatgtatttg atataaggag 108420 atccttttgg ctttagtact tctaaagtct ctggttgtcc ccaatcgtgg gaagatgttc 108480 cttctaatat tcttacatgg actttacgtt catgacaatt atgtaaatac tttttaaccc 108540 agcggtgcac taacaacaag ttactgtcat tagctggcgc taagtcatgg aagaagtctc 108600 caccccaaac acttagatcg atatcactta agttgttatc tttataatag aaacgactca 108660 tgttatccaa aatgtgttga gtggaggtat gagggtgtaa cgtatgttga tcagaacacc 108720 ataatgcatt aaatcttttt tccatgtctg ttcctagacg taaacaccct cattagttta 108780 atccgcaagt ggatcaaatt cttcaggttc tgacggtgtt ttttcgattg aaattggttc 108840 ttctaccgaa tggtcttcgt agtcaaaaag aaattcgttt tgagtaattt ccagtacaaa 108900 cttcttatcg gactcattga ccttttcgcc tttattaaat ctagtaataa tggtttcaag 108960 acgtttgaag atatcaccat caggatcgat ggattgtcct gctactttat acgtatcacg 109020 aatgtatatc aattgtttca ttgtgagcgg atgtacattg tgtttatcgt agaatgcagg 109080 agggatcaaa ctagttagag aatcctcatc taccccggcg tagttagtga tcgcattgac 109140 ttgttcagca aactgtttga tcaaagcggt cttttcggct tcgtcagtaa caaacttggc 109200 tttggaagca tagttactgc aaaaggcgag tttctccatt agatcttcgg gtagtaccat 109260 ctcggtgaac ttgcgaatga tcagaaccgg gtgacgttgt tcattgataa caattacacc 109320 tttggtgaag ttatcagtaa gctggttcca ggtctccata tcgaaatagt tcttatcacc 109380 agcatgacca atggcaaact gcgacaacca gttctctacg aagtactctt cttccatcaa 109440 cacgtgttct acaaatagac catccggggt ctggataaca cgttgtccag ctacttctgt 109500 ataagcaaag gtcttactta ggaattcgaa caaatcaccg tgagcgaatt tatcaacccc 109560 ttcgaaacct gcaacttctt taccttgcat attctttcct tcctttttga attaattcga 109620 atgttttacc attaacagaa actgacgttg ctaaatcata cagcttaccg tcttcttcta 109680 cttgtccaga tactgctaat gtaaacatct ttttaactgg ttcgtaatct ggtgatctaa 109740 ccaccacttc gacacctgtg aaacactcta aaagatagga acgtaaactt tcttccatat 109800 ctttaataaa gttatcaatc tggaaatcgt tctgatgtct tgcaacaaca tattgataac 109860 tataaatacc agtgaggata atcgattgat caatacggtt tgcaaaccaa taagcaataa 109920 gtcgatcaat ctttacagta ggttctttaa catatcctaa agtatccatg gtagcaacta 109980 caccttttgg catacactac tccttaaatt taaacaaaaa atttatcatt cttaatattg 110040 ctactctccc aattgggaga gtagcaacgt ataacttaac gcttattaaa ggtagccata 110100 ggacctttct tagctttgtt ttctttccac tggttataat aatagaaacc caacatagag 110160 aaggtaacta ccatcatagg agcaaagaaa gcaacaccaa caatttgagc agaagtcatg 110220 aggagattcc ttatctatat ctgtagagtt gaaaatacat attctattta tcactctagt 110280 aatataggtc tgaaaatcta tggatcttaa atgttagtct ttacaagcat tccagttctc 110340 attacaaagt gtaatgtatt ctgggagttt accttcatcg aataaacgtt tcatgaactt 110400 ataacacagt tcagttccat ctccataata caaactacaa tggagtttaa gctctgggaa 110460 ggaatgctca aacccaagct ctaggagctc tttaaaacgt ttctggatct cttctgactc 110520 aagggtaagg accagggcgt agaattgctt accgggcact cctagcttct ctacgttgat 110580 taccttagct ttgtatgatt tacgattaat ccctgggcta atatcaggat ctcgtttgtc 110640 atacatcaat gttgcgtgaa gatcgttagc tacaatgtta atcttagttg ctaatttctc 110700 gtgaaagtca tcggcacact taatctcttc tttttcaatt gctgcattaa tcgctacagc 110760 acttttcaaa tccatctgaa aagaggcgta tccagcaccc atgttaactc ctaagctttg 110820 tcggtgttgt aaacatttcg cgctttacga tcttctactc ggtcattgag ctctttcaat 110880 gcaccacgaa gatgttccaa agcgcgatca ttgtgaccac atttaaactg tccagtatta 110940 aagtgttcca aacgatcaat agcagaagcg attacacctt ctaaagtgaa accattttct 111000 ttattagtgt cacttgagtc ctggtactta agcattggca aaggtagttt acttcgacgt 111060 ccacttccat agtaacgatt gacatcaact tcagatcgtg ttacaacaca aatatcgtct 111120 tggtgtactt gtttcatttg tctatttcct taatttttta aagtaggtaa aagaactacc 111180 caaggataac tcctcaggta gttcagttta attactcttt atcttcttct gctttacgac 111240 gttcttcaac ctcttccaag gtaagaatgt ttccacccgc aatgttagac gagtcaaaca 111300 agttcttaat atggtgatca gttgcacgcc aggtgcgttg aatatcgaaa cgttctctag 111360 gacttagatg tgtaccttcg tccattgaat tatggtaagt gcgatagaag tattgatcac 111420 tttcattttg agtaactaac ccatccatcg ctttatcata gtaatagtta ccatgaccta 111480 taccagaaca caagtcagag aaatctccat catatccaga gacttgttca gtttcataca 111540 acgccatcat gttagggtta gccataatgt aattacgcat aaacccagtg gcttgttgtt 111600 ggaattgaac ttccgacaga taaccgattt cgaatcttcc tacgtagtgt cctgttctac 111660 caatacggtt agagaactcc cacatcttag aagacataaa gttactatga gctttcttta 111720 cagaatctac agtttcactc aaccatccag ttaagttttc gtatttctgt aacatatttc 111780 ccatgaagct atcgtagact tgagcagctt cactactcaa acttccacca caacctctat 111840 tgaaagctga tgttacgttc aaattagtcc tcctcaatcg gtgtattaag aagcacgcta 111900 tttatgttta agagattagt ccgtgttgca gcaacgaatc tacttgtttt aaacggcttg 111960 tttggatcga ccatttgatg gtgtccccag ttactatatg catttacttt acccgccata 112020 tcggggataa agaatagata catgttatcc agttcttcat tgtaacgttt cacaacggct 112080 ttcacttgat cgctactcaa gtattccgat actttcatac cggctgagat catatcttcg 112140 aggtcacaat ccttgtagac ccgtctaccg ttaacctggg cttccaggta cttgatcgtt 112200 gatcacatcg taactataac tagttaggac ttcgaggctg attgcccatt tctgtatctt 112260 gatccttagc actccgttct tccagaacaa agatattaag cttagaccat ctcatcattt 112320 ctttctgtct ttcgaccgcg ttcacactta tcctctcgga ttatgttgta gcatgatgag 112380 ctttagggtt tcccagcagt tagatagatt taaacacggc gcataccttt caccgtcaaa 112440 atcagcatta aattccttaa ctgtagtgat cggaatccgg atggatttat cttctacatc 112500 gcggttaaat tgtacaaaga aaccacgtgc cgacaaatac tgaatagaag gatttcgacc 112560 acaagttgca atagcgtatc gattactttc tacccagtta aagaactcct ctacaacagg 112620 atgtttaaag ttagcagcag agcggataat ctcctttact tttagtggag tgtaaccttt 112680 acgatacaac cagttggtta ggtgtttatc cagacacgta attccgtaca gccatggaac 112740 aataatagtg tctgaccgac aaacaccaga ttcgcctgtg atgatagaac gaccagtcat 112800 cggtaactta ccggcaccag cgtgataacg aatcatccct ttcttcttga ataggataga 112860 ttcagttaca tccaacatca tgcttttgag tttagtaaag atcttcccca tgatctctgc 112920 gttctcagta gaacgataat cgtaagctgg gtacatatca gcaattgtgt aaaagatctt 112980 ctcaagatca ctcttctcct tattaacata tttatctcgt tggtcagact cgacaataga 113040 ggttaccttg ttaggtagtg ggagatattg agctacagct cttgatttga atttttccca 113100 gaacatcgca taatgttcac ggttcttttc agtaagatcc agaacaccat tagtgtcgtg 113160 ttcaatagct gatctgataa tcaaatccat attgtcaacg aactcgttat acccaaattc 113220 gatattgagt gacaaacgga aagcttccag tttacaagct attttaaacg cactatgact 113280 tgggtctcta aaccgttttt catttctaaa ctctttgtta atccaatact ccactagatt 113340 aaccttaggg gttttggtgt tgagtttacg gaagaatact tccgcaatag ttgggttaat 113400 aaaacctgac acattagcag gagtgcgaag ccagactttg gtttcgatct tctcaccaag 113460 tggtttagta acaggatctc cacaactgtc acaaacgaaa cttgtaccaa ggtacgcatt 113520 agtacgatgt ttcttgcaag tacaacttgc tactgtatcg aaattgtttc cttcgtactc 113580 agtacgtagt agagcagtaa tcttttcacg atcttcttct atattaaaat cgaaatcatt 113640 cagatagatc ggatgaactg tagtggtatc atgccgataa ttgaaatctt caatatctgg 113700 ataaagaggt tggtaaaagc tttcgtcatc accttctggt acataacctg actctccaat 113760 gattttatca aatagagtgg ttggaagaag atgttgtatt tggtattgct caagtacatt 113820 cgctaaagtt gacatacgaa aaaattacct ccaggtaata aaactagaga ggaggaatta 113880 ccctcctctc tagtagttac atcttaacgt ttatcagctc tattagaact gggtgtacat 113940 cacgttgttc attacgttct gagttaccgg tgcgttagac aggctagcac ccatggtcat 114000 gttcaggatt tcgttctgaa cgtgcatggt ccagttagcg gcagcgttgt taccggatac 114060 agacagagta ccggcagcag acattgcttg agccagagtg ttgaagaagg actggttaaa 114120 tacataacgc agactccaac cttcaacgat cacatcgtta ttgaacattg cttgcaggcg 114180 gttcaggatg ttgtactgac ggatacgagt atcgatgtta cccatgctac cttgcagcag 114240 agcgttgtac tcgttgatcg ctacttcatt ggtaccgtag tactcaggct gacgcaggaa 114300 cataccatct acttcaccca gatcaaacca agcattacct ttcttggcga taccgtaagg 114360 acgaatgatg ttggtacgat gcatgatcgc atcaccaaac gcccactctt tagacttgtc 114420 acggtttgca cctttctcag tgttctcttt agccagagca gagaacttac caccggtcag 114480 cagatcacac agggagatca tggagcgaac gtaggtagag gacttgtcac cagaggtgat 114540 accgaaccag aagtcattgt tactggtttc atctacataa ccgatcagat cgattgcgta 114600 tactgcttga ggtgcaacat aacgctggat ccagtcattg gttactgcga tgttggtgat 114660 gttcttgttg gtgaggttgt gatcagcacc gtacacagga cccaggatag aagccatgta 114720 gttgttgaac acacccaagt taccacggtt accaacctgt tgaccacgga acgcttcaga 114780 gaagaatacc ggagcgttag ctgccagact tgcgaacaga ccaagcagtt gagtcatcag 114840 ggagttatta tgatgcaggg tttcaccagg gttggacata ccagctacaa caaccggaac 114900 gatcggacca caaggacgac cagggttacg agcacggaca tcgttgaact gacccggaga 114960 catggtttcc agttggacgt tcaggtaaga tgtcaggata gtcttagcgg tgttgttacc 115020 gtagttggtc atgttgtttt tgttggcagt agccagctta acagccaggt tatacggaac 115080 aggcagacca tcaacaacca gttgatgaac agattcaaca cgagccagtg cagcttcatg 115140 ttgaccaaac agtttaccac cagcaaacgg gttgggcagt tgaccaccag ctttctgagt 115200 ttccagagca gccatgttgg taataccagt ctgccactct ttgagcagct tgtgaccaac 115260 tttagcagcc atatcttcac cagtgatacc ggctttgata taacgttcca ggttcatcac 115320 catcggtgca gtgatcacga cgttggtcat ggtcttacca tcgatgactt tgaagctttc 115380 cttaactttc ttcattacgt cattggtcat gaaggaagtc ggagtcttag cgtaaccacg 115440 cggagcttcg ttacccattt ggatggtatc ggtagcatca gtgatacctg ctttgtagaa 115500 caggatcggc attacgtagc agctagtacc cagtacggtg tacattgcga tacccggcag 115560 atgcggagtg atgtcagagg tcagctgttg catgaaacgc ggcagagttg ctttctggat 115620 ttcaggagcg gtgttagcca gcagctcttt aactttctct tgcaggtact tgctcacatc 115680 agcaacttca gttgcggagt gggaggaagt gatcaggttg gtgctaccaa acagagcagc 115740 cagaggagaa ccagaaccgt tagaagaagt acccagaccc agggtggagt tcatagcgtt 115800 gttttcgttg ttgttaactt gcatgataat ttcctttagc taaaagttat ttaaatcact 115860 agtggcgggt taattaagta attgaaaata cttctcttac ttatcactta ggtaatatag 115920 gtttgaaaaa ttatagaact ataaaaattg tcacaaatta gtcattccta cgttgatcgt 115980 atgacagaat tttccatacg acgtacagct accgctttaa cacctaggat gaacctagat 116040 gtttgtacat ataatactac attacttatc tttttaagtt gagttaccat atgtctcatt 116100 tcaaactaaa gagcaatggg ttacaatact cagtaccaca gtacggaggt cttggtaacc 116160 tacaacgtat tatagctaga aacagagata actataggaa gtatttccaa ctaggtaatc 116220 gcgttgttcc tagtcaacat ccattagttc aactgcttca gcacttttcg gttgacattg 116280 tatcaggatc agagtctctt tttaatttgg tggaattaaa aggtagacaa tacgcaagct 116340 tggttaacct tacctcgtta tataacaaag gtaaagatca ccttgataca gtatttcctg 116400 aaagcaatca tcatactctt tttgtcgttc cgttcgataa tgagtacggg ttgacaatag 116460 atgatctctc tcgtgaaaaa gtattggaac aaccaatact ctctactatc ttctctacca 116520 gtaatgttca atactgggat ctgtctaagt tattagacag tgagattaga aagagtcaag 116580 aagatttcta ttctgctata caagtagata tccaccgact agtgctaagt tattactatt 116640 acttaactga tagagttagt aataatatca atgtgggatt gactccccag cactttatct 116700 acttagtatt gatggattat tatccagtac ataatgaaac agtaatgtta aattatacag 116760 ctggtgataa aatagtcatt caggatccac cattcgcgtt tacagactac tctatggact 116820 taggtaagta tgtaacgtgg aagaaaaaga aattgatgtc agatcgactg agaagcttta 116880 ccgagtatat ggaatatcat cctactcttt attctaactc aggacctttc attaactgtg 116940 gtaaatccca gatgtttatt cagctaggtt ggatctacac cctagccgct ttatactggg 117000 tgaaaccata tctctcttat atggattaca tgggatatca agatcctatt atagaagctc 117060 aattaagaac tttctataaa ctgaatcctg cttttattct taatcaaata aaagatcctt 117120 attggagaaa caagttccat aatgttcatt tagatttaaa agaaagatga taattatacc 117180 tctaccttcc aaatgggaag gtagaggtta aattacataa tattgattaa tgttcgtccg 117240 atactaaacg agtaatactg tcattcatca tgtacaaacc tgtagagtgg agtacagtgt 117300 aaacactctt gaggttttgt tttaacaagg ttctgtagtc aatagcttgt ttgaactcta 117360 gggggatatc tttcaagttc tgagctcttt ccatagggag ataaaggttt gttaacttat 117420 ctttaccttt actttctagg aagctcttaa acttctcacg aatggtatta tcttcaatct 117480 tttccaaata agcattgagt tttgatttgg aagtaagatc aacagacatt ttaatcccag 117540 tgtaaggaag ttcaggagct ggtccgtact tctctgagaa tacttcttcc caaagagagt 117600 gataaagata tttttcagaa tctgggttag tataagcgct ggctggttta atactttcac 117660 gactaagcca actataatcg ccattttgaa tatcatcgac gatacctctt tccagctcac 117720 caactccaaa tagtatttct ggagcgttca actgtttacc agatttaatg gcgtctagtg 117780 tggaaaccat taattcctga gctttgtctt taataacagt agcgattttt gaagacttga 117840 gatgaacacc tttaatttcc atttctgcct cttcgttcac tacaccttct accatatctt 117900 gataagcata ataatgcttg gacatgtcag ttgtaacata acctgagaag aaatattcat 117960 ttttcatatt aagtagatct aagtttttct tagacacatt catattgcag gatagttgtg 118020 catgttgatc aacagagacc atgcgaataa aatacgtaag tactccgttc aacatcacac 118080 cttgcttttg atcactagtg taagagtcta tcatttcatc aacactataa atacttgagt 118140 cagtatcact agttaagaca caatccctaa cggcatttac aacattaaat aatccggtag 118200 gtggaattgg tgatttaaaa aacaccttaa taaaatcact gtattctttt tccacttgaa 118260 catgatgata atttaatgcc tgtacttgtt ctttacttgg atcccttggg agcttggaaa 118320 cacaaagaac atatctatca ccattatcag gtttaagtag tttagattca tcaacttctg 118380 gtatatgaca ccatttatca aagaaagcgc atacaacatc cctgttatgg ttgaacagag 118440 aaaacaagtc tagtgtataa agtatagacg ccttttcaat aggtttcagt ttatccacaa 118500 aggtctctat aagactcatt tgtgattcgg aatcccagta tctactagag caatgcttaa 118560 cccttttcat tagatcttcg ctagttgggt aatgaagttt atacttttcc attacctgtt 118620 caagtagttt aaaatcagtc acttgaattc tagctatcat agactgcaag gtagcatcag 118680 ggttatgata gaaacgatta ccggcaatga actgttcgtt ggttaggtta gctgtagagg 118740 tcagacatct tgttgtggaa gtgagtgacg tgtgccccgt gtgattacta attggagttc 118800 cgccagagga catggctccg gattgggcgt tgttaaagat cttaaaggcg ttttgtaact 118860 catgatactt accataaaga tctttatcgt ttactgcttt tgcatcttga cgtaaatttt 118920 tatagtactt acggttagcg atgaataaac gagttccgat ggagtttacg cactcctctt 118980 catcagagtt agtatacgct atcatactag gtgagaagtg atagttctta tcttgtacgt 119040 gttttaatac agatgagaat gggataatct ttacttctct atcacctact ttattcttaa 119100 tgatgacttt agcacgttta gatttatatt gttctttgtt ggctttgaaa taagttaaaa 119160 gattagcttt tacaacttct ttatcttcac cttgtactct actaatcaat tccgaatatt 119220 gttcaataga gtgtttaata atgttacgat ctgattcgta cgtttctgag agaaacggat 119280 ttgattctga cataactgtt ccctcaacag aaattatgaa aaacaaatga taggaggtta 119340 aatgtttagt tcgctactaa attgtaatcg tggtgaaaag ataaaaagag aacaaaggta 119400 aagactaacc caacccccaa ttaaggaggt tgggttagaa ttagttaagg gattaagact 119460 tatctctaat atcaatggtg taaggtacac ctagattagc tagaaagtct tttaaagggc 119520 tttcaaagcg ttgttcccaa gtagtaatag taataagggc agaacgacct ttggttactt 119580 ctagagaact tggattaatc cagggataac cgataaccaa gagattggat tgagtgggat 119640 ctggtctaat taatagatag tcgtaacgag acggatcgtt aacattatct acggtgtttt 119700 taaacattgg gtagaaagct tggtgtttta cattaagttc tggatcaata ctagaagcta 119760 ctgtataatc aaccacacct gctaccaaaa cacctcgata ttgatctcca aaaatacccg 119820 gagtaatcat atcgaaatta actaggtcac ctttttgaat ttcagacaac ttcatagtgt 119880 tcaaccttgg caagtaatag agggaatgta atcaaagcat ttccataggt cactacttta 119940 cctggtgaat ctattacttc taactgtaaa gaaccaggtt catcaccaat caattggttt 120000 ttgatctgtt cttctaagaa agaatctaaa ggatcttccc cgataagttt attactttca 120060 atgtgttcca gaatagtttc agcaatagct agagcttctt ctggatcaat gtctaagtaa 120120 tatccgtctt tatcattacc aacttcttgg tgaatctcgg atagaatccg atagatttca 120180 taaccttccc aaacactttg cggtgtagag cctacgatta gttctactag aaaactgatc 120240 ggattagttt catcattaaa gtgaggggaa atcctgacca gttctaaata acgatcggct 120300 agtttttcaa ctactctatc tggatcttca ttggtggagg aaagaaactc attccttcgt 120360 tttaaacgtt ctgaaacact cttgaacgcc tttaacaata tctcataggt caaaggttcg 120420 tcttgaattc ctaaacgctc aacgattccc ccaatgagtt catcgtaatt aaacgcatta 120480 aggtagacaa acatgtcgtg tccttactta caagtgagag tcagatgtag acatttacca 120540 tctgacttag tatcacaagt taccagctca tggtcacgag aaagtccagt aagcaatcca 120600 ttaagctcca gatattgatt agtagcgcga atatctgcta cttcattacc tgttactagt 120660 gcatcactag agaacccttc tgggttaact gtcagttgat gttgtacacc atggacattc 120720 atcaagagac caactgcatt agtaacagtc tcaatcggaa cacctgggaa tgtaatcagt 120780 tgggtataga ttttaggttc agacattcaa ttgtccttct ataacaataa actgttgatt 120840 ttcaaaataa cacttctgcc attcttcagt ggaatctaaa gtttggataa gtaaatcaag 120900 ttgttgtctt acttcttggt ttaacataaa tccttgtgta ggttccaaca tctgtaacct 120960 gatagataaa acttcgggat tacgattttg aacatactct tgtgctattt caaagaaacg 121020 ggtcgcattc agtgaccact tgttcacaat catccacaag ggatgaatgt tggtggtcga 121080 gtaccggatc atcctgttct ccttgtgcaa tgataaagtt gaaattatcc agataacgaa 121140 ccagagtata cctggcttgt agatccagtc ctaaattgga aataaggaat tctctaaact 121200 gtagtagtaa atcatcaaac tcttctatta acgtttcaaa atcaaaccag gatgttaata 121260 ccggttcatc tacataacca actagagaga aaaccccaca ctttctaatt agataggttt 121320 gaaacgcagg aacaaggaat ggataatctt ttctaactat cattcttgat gagtacattc 121380 ctttctcatc aatagcttgt tctataaacg gaaagaagtt ggtgaagtta atgactgtaa 121440 atcccaaaga gctcatttaa catctcctga gatgggtcat cagatacagc ttgagaaaca 121500 tcttccttat cttccttagg agtaaagaag aggaacgtct cttccaaatc catacagata 121560 cgataacaag gaatattatt aaatttccgt tcaagtaact tatacttcaa ccggggatca 121620 aaacctgcgg tgtagaactg tcttttaata tccaccacca ttccaatcac aatttcgcca 121680 aggaaggtga attgacaatc gttcttgtga tactcttcac aatacaggta gaaagagtcg 121740 tcaggtttgt taactttatc attgagaaca tgaacaatac aatctagagc tagtttactg 121800 taatagatcg cattattgta gtccagagtt tctgtcgctt gtccacctga cattacacag 121860 gtaagagcaa cttgtgattt taatagattg taatcgatat gaaacataac caagccttgt 121920 taagtaatat cgagttgaaa gtgaagatga cctaagttgg ttaaggtcgc ataactcggg 121980 gtaggtacag tgagtagttt ctcatccaca tatcctttta ctaattcaaa aagataactg 122040 tgttcatgag agagacttct actatacggg gaaggtggga gagggatacc atggtcaaga 122100 cacgcgtctt gtaaaatgga atatgccaaa ctctctttag cttccgacaa tacagttaag 122160 ttgttgccta tactagacag attaaaaaga atttgcataa taagttagag gagggttaat 122220 cccctcctct actccattta tattaacaga acataccgtg gtcatcagaa ccttggctca 122280 gatctttttg tactttgtat ttaccagaga gttcagcttg tttggtctct tgttgcttca 122340 tcattacttc cagctcatta agagtagaac cgtgatcaag cagagcgtga gctgcattaa 122400 tcagaccttc tgtttcaggt ccgaacaaac cagctttacg atacaggaga ttatcaaacg 122460 gagctttgat ctgatcgatg tcattgaaca gagagatgca cgcaactgga gtacgcttgt 122520 agtctttcac attctcatcg ttacagaacg acacttgagt aagaatcgga tctgctttaa 122580 ccacattggt aaagaagaag aagttcttaa catcggcata atcgatgcgt tcgttttgca 122640 gattgaacat catgactgcg ttgttaatta cttccaacac attgcggtta acttcgcctt 122700 gagtacgacc aagctggttt tcacgatatg caaacagcac cggacaacca agtttggttt 122760 gtgcattcag agaacgcaga gtagaaatag tgttatcaaa ctccttaata gaagttgtat 122820 caccaattac tactgacaaa actgggattt cacgttccaa cattgcacgt accaggaacg 122880 gaccaatacc tgaacctgag ccgccagctg ctgagaacac tacgatgttg atactattag 122940 gttgatgttt agccagaact tgttttacaa agtcagggta acgtgagatg ttggcgctct 123000 tatcagaacc agaaccacga gtatcaccca gacgttcgat ttcaaacaga ccatcaatag 123060 ctgggttagc gtcggaggta tccaaaccaa ctacttgctt gataaactgt tgagacttag 123120 actctttaag cagttggttc agaatgttaa taccagcacc accagcacca tagatattga 123180 agcaacgatc cattttcttc tcctagataa catattgatt aaaacgagct gagagctctt 123240 gtaaacgatt cttttctcta aagtattgaa tcgtacgtat ttaataaaga aattgattta 123300 aacgcaatac agagcgttta caaagcatga ctgatatgtt gctcaagaga ttcttcaatc 123360 agtcgataga tttcgctatc cagctgatct tcttcttcga tattctcaag agcgtgagtt 123420 gactcataag taccatgaag cggaacacca tggataataa ttgattcttt tgttttaggt 123480 tctgacataa acgcagtatt gatatatacc agaaacttcc cagggaattc tgtctttaat 123540 gctgtaacag aaatcttaaa ttcagttccg gtgcaagtag tactgaaact gaacatttta 123600 gcttcttcag ttttgatttc agaaggaaac ggtttaccct tgatatgatc aaggaactca 123660 ctcacatccc gcttaatcat aacgattaac ttttctacac tatttgacat taaagctttc 123720 ctcaagcttg tcgagtttct ctgcaaggag aacagatgaa gatgaaatga tctcatccat 123780 ccctttgtat agtactcgat aggatttacg aaatatcgat ttagtgaact ttttcattgg 123840 tttaatatgg atcaatgaaa cgcatacatt gttctctgga ttatcaagag cgatcttgat 123900 agaaacaatg ataacatcct gtttattaac ccgatatctg aacgtggaaa agaaccttaa 123960 gttatcatct cgcaacatac ctttgataaa ataaactttg gggtaactct tgggtttttc 124020 ttcaaagagt tctcctagga atattttctt tattaaatcg gatttgttca tcctagtgac 124080 cctgtgtgtt ggtttgatgg ctaatacgaa tatagttaca tgatgaactc cttagtcaaa 124140 attaaaactc ttcctactgg tacacgataa taatatatgt ttgaaaaatt atagaagaga 124200 caaaattaaa atacattaag ccaccctcta caccttcgca ggtgtagagg gtataactgt 124260 taacgcctga taatgataac aggatgttgg atattgactg gttgtttatg ttcttgttta 124320 gccttaatca tcccgatccc aaaattgcga ttgtaaatat caggtacaaa tgtttcacca 124380 ttgtctttac tagtaccaag atcagatttg ttaattgcgt caattacatc actgagactc 124440 atcataggtt gtttggcaat attcagaatc tctctttgtt ctgaacaacc tggacagtct 124500 ccatcacaag cgtgttcttg acttgcttga tgacgatact cttctttacg atgaaccata 124560 gacatagcgt cagcaaagat aacaccagca aagaaacctg ctagttgtgt gccatcgtgt 124620 cggaactgat catggttatc aaggccaaag tgtttgacga ttatgtcttt gacactttca 124680 acctgcattc cattaaaagt agacatcacg tactggtgaa gtttgtttgc atcttcccag 124740 gtctcacatt gttcaatacg accgtgaagt tcaccaatat aaccatggga aaccagatca 124800 gacagtttac gtttgagaat ctgcatatcc atgttcatga acattgtagc aagtacagta 124860 gcgataccag gaacgtgttt gatagatgtg atggtgatcc cgaactgatt acaaacgtca 124920 gcttgatcaa ctacagagag cttggagaaa cactcagcaa tgtcttcgat cttgccacca 124980 gagaagataa tgcgttttgc atcagaatag aaatacagtt tggtgtagaa ttgttcttgc 125040 ttcatctctt tatccttaat tggtttattt agaatttcct gaaccgcttg ggtgtcatct 125100 gaaacagaat caccttttgg ttctgacgaa gctgtttctt tatcaaataa gaatgaacgt 125160 agtgaattga tagtaaaagt tcgacgttca tatgaatcta gtttttctaa gatcatattc 125220 accacgtttt taggtatacc gaagatatct acaaggagtt ctagctggta agctggctcg 125280 aggtcaagtg cgtgttctat agtttcatta aataaatgta ggtttaagca ctgtccttga 125340 aaagctcgca caagtttttc acgaggatcg tgtcgggtat tttggttcac ctcacctaga 125400 aaaagatcta ccttgcgggt caatgtcctt tctaataaat gataatgaaa attctctaac 125460 acgtccttgt attcttctat attttctaat ttgttaatct cggagagaac atccaggaga 125520 taactccaat tgaaaaatat agttcctaat ttttctttga tatcctctaa aattgtagca 125580 acaccaactt tattttgcaa gtgtccggtt tctggatgat taatgacagt tttcaaacac 125640 ttatacatcc cgtgttcatc ttcctgttta ataaacttat gttcggtaaa ttgatcagct 125700 ttcaaaaacg acattgacat aacgatttgt tcaataataa atttagcgtt catagtaacc 125760 tctttctaga ttaatggatt tggttgttta taacagtaat ttctcttcca gcaggaagtc 125820 ttacaaaatc ttctttggaa atactacagt gatcgaattt aattaatcca tgtcttgtat 125880 cgccaaagtg agaaatctct gattcgttaa ttacacaacg acttttaata gaaacaaagt 125940 gtagcttaga attgttcaat tcaggatcaa ataagaaact agatttaaga aaaatcttac 126000 ctctaagtat gatgtctttt tgaacatcta ttctggtgat accaaataac tccaagataa 126060 gctcttttct cttcaacgac aacaagatat cgtttaaggt accatacatc aaatccgatc 126120 cttgcttagg attcagaggt ttgaaataaa gcactaaact accctttagt tgattatcat 126180 ggaatacaac tttatttcca tctatcgcat aacttatcct accttctttc atcattataa 126240 ttattcctat cgtacttatt caactagact taaaagagta acccaggaga tcctgggtta 126300 ctctagatag gtttaaataa caactttcag atctttaaaa gcaagaccat taatgtaaac 126360 agtcatccaa gcaagtttga tttccagctt gagtttatcc caggaagtgt tctcttcaaa 126420 gtccagaacg ttttcacctg ctgctcggta tagcaactga ccttcactat caactacttg 126480 aagatcgtaa ccacgtactt caggttccaa taccatacca aaccccttgg gaaggagttc 126540 ggtcatctta tcagtatcgt taagatcaac gtactgtata aacttagtct cttcacacca 126600 ctgatcataa gctttatggg ctaggatttt acccaaacta ttaataaaga tcaggagatg 126660 atttccataa tactcctcag tgagttcttc ctcttgaact tctgagtatc cgaagttaag 126720 atcacctgaa tatcccaacc caggtatttt agcaacaaca gaaagatcac cttcttcatt 126780 acactgattc cagaactcca ctttaatggt ttcgttcagt tcaatgacgt tgctaaaccc 126840 aaccaattgg gtttgtttga agttcttacg tgcagtttcg ataccgctcc agaacaacgt 126900 cacattatcc agtaattcag ttgcgctaac agccatttcc atttgtatta tctcctagac 126960 tagtttaaag tagtcgatgc ggtttgtttc atttcgcgag agagtttaat aagttcttgt 127020 tcaggaacat ctcctaccac atgtttcacg tgaacactaa acttaccaaa catatttccg 127080 ttcaatttca gtttgaaaga agccactaca ctttctttgt tgctattgta aacaggacta 127140 ttccaattac atacttggtg agtcccaaat ttacgatatt caggcagagc actgaacaca 127200 acagttttac catcaatatt gaattcagct ttactgttaa gttcaatctt gttcttcttg 127260 gtttgattaa tcagactgtt gaggaacact accatcttct tttcaaactt actatctact 127320 tgttgcatta ggtttatccc tttctatttt gagttattag atcgaaacta gcttatccaa 127380 ccattccgga ttataatcac ccttcatgca aagccaggtc aaatcatcgg taaagttatc 127440 aattaccttg caaccgtaga tatcttgttc ggtagaaacg gtagttggat tgtggtcagc 127500 gtagttagta agcttccaag tgctggtgtt ttctacaatg ttaacacttc caattccatt 127560 aaggtgatga tctctggaat tcagaacaac tgattcataa cgaagtgtcc cttcttcgga 127620 tttgggaatc cctaaccaac tatggtaaga gtaaccatta ctacgtttct taacttcgat 127680 tgaaggataa tagtgattga acagatgact tacatcacct acttcagctt catgatactg 127740 tttcagcaaa ctgtcaacat cgcaagctag gatcttaaag aaaatctttc tgataaaatc 127800 gaatattcct tcattgatca tttcaaccac gtgagaagga tcgatctttt taccgaacgt 127860 gtcagacgga atttcagttt ccagactaaa cttttcagcg aggttcaaac taacctttac 127920 accatttggg attttcaaaa acagtaactt acacttaatc ccataaattt caaaaggttg 127980 gataggtaac accgagttac cgctacgaat tgcaatgtag ttattgatac ggtcaagcac 128040 ttctttacta agcaaaggtg ttgcttgcat aagttgttta atagtaactt tcataatcgt 128100 tccttaaata ataaatgccg ggatgtcaat atactcacca ttgtaactta agtattcatt 128160 taggagtcgg tctataacca cgtatgatgg agatgtttta ctcttaccat cagtctccca 128220 ctttttgtaa ctaattgaca gttctgttga gttatttaaa ctgcaagcca ctctaaagaa 128280 cattaatgtt cttagctcta catttattgc ttttgaaagt tcattgatac tattcggatt 128340 attttggtca attaggtacg tggtcaaaaa tattggttgg gtacttcctt tggtgattgt 128400 tacatctgcg tgaacattat tttcagaaat tcttttatta atttctatac ggctgtcttt 128460 taatgaaaag atcacggccc cgtcatgctg tacattaggg tgagtgatga gttgagtatc 128520 gataatttct aaatattttt ttatctcatt ggcggtaatt ttcataacct ttattctccc 128580 tagactttga atattgattt aaacgagctg tactgaagct gttagtaact tacggaacgg 128640 agctttgact ttattcaacc cggagtggaa attgtccata gcttgttcta cttcgttaca 128700 gataacttta tccaatttct tagtataaac ataatagtaa tcgagatcat caaataccat 128760 ctgtttagtt tcacctagtc gaacaaacat ttgttttacc aaagcttgct caataactct 128820 gatgaaatct ttattgtacc aggacttgca atcaccaaga gaaagtgaga gaagttgttt 128880 actttcacca gaacttccgt gaatgtagat gttgagcatt cgctcaacat caaggagttc 128940 tactttcaat tccataagga gattaccttt gagcttacgg aattggtaat caccaggttg 129000 aagaaagaca ttatggaaca tcacagtctt caagcacgct ttggtcaaag ttttcaattc 129060 agctacattt tcaataacag acatttccta gactcctttg aaatacactt tgtaacatta 129120 catcttaata atatctatgt gaaaaattat agaacttaaa ttatattgtt ttatgtggac 129180 taaacacgta aacccatttg ttcaataagt ttctgttaaa caatttaggt gcatcgtatt 129240 ccggttcacg ttcaaatgta ttaacaaaac gcacgacttt ctttttctta gggaatatta 129300 atttagcagt tgtacctgga acaggagtta aaattaaacc agagaagttc cattcaaaat 129360 aaaatagtcc aactctggtt tcacctagtt gattaatgaa tctaatcctt cttggttttg 129420 attcagttcc tacaacccag cttcttaaac ctgtgatatc ttccttgtag aaactaatag 129480 gaacatcttt tttcacatca aaccaaaaac taaaccaaaa agctttaaaa agttctaaca 129540 tccaaaatgc ctttgtaatg attatctaaa tgctctctga acttttgtgc tactggccaa 129600 atacctgttt tgcgataata cttatcaatt tcacaaacat cagaataacg taccagattg 129660 tcaattgtcg tattcatctt cctaagaaga aattgtgttg aggtaatatt cagacagcag 129720 agtacttccc aagtatcgtc acctataaca aaacgatagt actgttcttc gttattgagt 129780 agtctggtga gataacttac caaaattcga tcgatctcag tggtttcttc ttttccagac 129840 ttcatcatca agacatcttg ttcctgatta atcaatccgc aaacccaaac aagttcattg 129900 gtatcaggtt cttcagattc ctcttctcga tagataaaga aactatcgct cttgagtacg 129960 tggctaaacc cctcctcaga gctcgtgaga agcgttataa gaccgttctc actaacggca 130020 gtatgtttat cggtaaaatg aaacaaaaca cctgagagtg ttctggcttc gcttaaagta 130080 agttcttcaa ctttataagt cttcataaac gaccccatta atgcataaca cccatggtac 130140 cgatgaaatc tagaagtgta tcatcaacat tatcttcttt ggaaatttct attgggttaa 130200 ggttaatatc gaccctccca actttaacaa ctagtatatt taacctacca tctttattcc 130260 ttggtccaaa taccaaaaca cccatccaac atttactacc atcttcacct tcaactacaa 130320 tgtgatgaaa ttcagaagca gctttgacca ttgtaaaccc tttctgatca tcggataaaa 130380 gtacctcgtc aaatccttca tcccagcatt tcattcttcg tttaccactt cttacaaaac 130440 ttttaccgtt tagtttggca gcaagttgaa aggtgatatt atttacttcg atctctgaca 130500 ttttctatat tcctttaaat tagaattact ttaacatctt gcagaagttc acctttaatg 130560 aacttccctt gtaatgtctt taccaaacct aaacaccatt tattccagtg tttagtatta 130620 atcttaatta caacatcttt cccaattaag ttacaaagtt tattgtaatc atcttcagta 130680 aacttgtaat ctttgtttaa ataactatct aactttagat ctttcattac acagttaaag 130740 acgtaataac tcatggaatc aattaaccat tccattttat cattaattga ttgaaagtta 130800 caaaaagatc caatagtaat ggcttgttct ggattacgtt taactaagct aacaatagtt 130860 ctagtttcac cctttactag atgtagatag aagttatcat tgagattagt ttcgtgttcc 130920 actatacaac tatcatttaa cagaaatcct ttttgtaaag taatatctga cccaatagac 130980 tgctttacca aatagttggt aatattatct ttcaaaatct aatcctccat aaagttaact 131040 cctacctagg taggagttaa cttagcattt gttaattagt gaaacaactt agtagtcaaa 131100 gtagctacaa tctctgatac gcagtcggtg ctcttcaact tattgatttc taccttcacc 131160 agagcgtctg taacgacgtt tgtctgtaaa gagcagctga tggtcacagt tccgtcttcg 131220 tcccatgtat cgtgttctac gcacatttta aaacgatgtg gataactagt atccaagaag 131280 cgataaatat cttgaccaaa tagtggttta gattctacac ttttagtttt aatcccagtg 131340 attactttag ccagttcttc ctgaaactta ctgtgagcta cttgattcaa catcccttta 131400 ctctccttag cttgttttaa cataaaccca ccaatgatct ttagtgcaag gaaaagaaac 131460 atgattttcg ttcaattcac aatcaagttc tttcattggc gtaaaatgtt catctaagta 131520 attaaagaaa tcaacatcac ctgtacaacc accactacct tgaccattat agatcaatac 131580 ttgaccttta gtcatcttgc taacaacttg ataagcaaaa ggatcagcat aaggtggcca 131640 gttcattaca attacgtcat aactactatc aacgtaatct aaactattac catcaatacc 131700 aaagtgacga ggagttcttt catcccagta ttgaggatcc caaatatcta ctgcattgta 131760 atcctctacc ccgccctgtt tcatgtgagc tgcaaagtag cctgtaccag accctacctc 131820 taatacactt ttacccttaa ggaagttaac caatacttct ttaacttcag ttgtgagaat 131880 aaaccaacca atacgactag tgtatctaca acgtacatca taactatctg caaaactaaa 131940 cttgtgttct ttaaagaacg acttaggtaa agtaggcgga agttcattaa ctcttacagc 132000 catgtgatca ttaaacttgt taatagccag atcaggacaa ttcattttca tttcccctta 132060 ttctacactt aaggtttcgt aatccataat ttcacaatta caaaaagctg ctttaacagg 132120 ctttaagaga gttgggagta acataaagtt tacttcgcca gttctctttt tatttaacat 132180 gctcaaaaca ccatcatggt ttaaatccgg attgtactta caaattagat cagcaagttt 132240 cttccttcct ttagttctta aaacctgttg atcaacccac atgtcaaaca tcttcccacc 132300 aaacaagtta agcaagaacc gctctacttt caagaacact tcggaatctt taacacttac 132360 agctgggaag tattcaccaa atccaaaatc ctttacttct ttggtaactg tatcaattac 132420 ggaaatggag taacgtaaac cgtaagcacg tttcattacc aatctgtaat ccatatcaac 132480 agttataaca aaactgatct cttcgatctc tttacgaata aacttaacaa gttctacact 132540 tttagaacca atgttacttt tcaatacatc catacgtaat ttcattttct tatctcctag 132600 acttaatgta aaagtttaat aaactagatt ttcaccaatt gatttaacaa aatcataaaa 132660 atctgaatct tgcaacgttc caggcgtaaa cgccagttct ttagatcctg attttaattt 132720 agtaataact ccaactgtta tttcagctgt aaacaaatca actatatcgc tacccttacc 132780 actatcaaac ccaaaataaa gataataatc tatcggttct ttaattacat gtttaaaatg 132840 attctccata attagatcac gttttacaat tccataataa catttaccgt atattgaaac 132900 tggtactctt tgatctaatt taatcgtttc atgagtttct ttactttgaa ctagtatatt 132960 actagttaca gcccttatca atgaactagt aagtattatc aatccagatg aacttagcat 133020 aaactgttct ctaagttaat tcattataaa caaacataaa tctttcttac cccaggttat 133080 tcacccagag taagttgttt gttattccta tatcgctttc taatcaattc taattaatca 133140 atattctcta tttcacttca tttctattta tcagcttatt ctcaattcct attactctct 133200 ataatcctct ctatcacttt aactttaacc cttaactata cctaagctag gttaactatc 133260 tctataactc aattacaatt agaataatca aatctaatta actattctaa ttaaaactag 133320 ttattactaa ctaaagacta cacattaaag aataaaggat gattacttcg taatcactta 133380 tatattaatt aataaagaca taaacccctc ccagtccaac cagggatttc ctcgttaaca 133440 tacaatagat atttcacgta ataaaataaa tttattactc taactatcct aatactctct 133500 gtaaactcat ataacgaatt caatagttta atagttaact tatctcgtat atctaattac 133560 ttcttctcta atccattcct attcgattat aatcatcaat ttaaccttag aacaaacata 133620 tagattactc acccagagat ctctctccag atgaatgttt aatgttaatt gtattctagt 133680 ttatctatgt ttctatttaa taatacttat tactgattta aactcataat aatgaagaag 133740 tatatacttc tgctcttata ggcaaccaga ccggaggggg gtgggggttt cctagtcaac 133800 tggtttaagt cactgggtaa gtattattca agaacatagt atagtaattt aaattaataa 133860 attaatgtta actagtttaa cacctacaaa atgtaaacca ctctctagcc gttaagctag 133920 agagtggatg ttaacgactt acttaaaaat caaatcacta atactttcag ctaccaaatg 133980 agagatgtta ctcttctcat gccaattata ttcttcatta ctgatatcca tagaacgtct 134040 agtgtgtaaa caagggaaca aactacgatt gaccaaccct gtagtgaatg aaacacctat 134100 agtgatatga tctttaccaa acatgttgta tttgataaac ccttttacca caatccaatt 134160 accttccttg aatcccccag tattaaaagt aaactcttta cgacgtctag cgtaaagatc 134220 aagaaaggat ggctttggaa tctcaataga gtttaaaacg ttgtgagaaa tctcctgtgt 134280 aaaaaactgt ttagcatacg gattggggag tcccaaattt tctctaattc tgtctaaaga 134340 gattctatca aaataattac ctactgcacc aaccctgaaa ctcttatcat caacaaacaa 134400 ccagaaacga tgtttgctat cacgactgat tttgatgtct ttaccgcaga ctacaccaat 134460 acggatagta actgaggtaa tggatttagg agcagttttg aaagcttcgt caattgtcct 134520 gttgacatgc ccaatgtctt tatagagttt aacaaagtaa tcctcaagac caagtttaaa 134580 taaatcatac atggttttgt tataatcaac atcaaaatct acatggtcag gataacaagt 134640 taaattgaca gtgcgatcga tttgcataat agttcctatc tagaatttag gaccaagttc 134700 ctgacatact tgtttagcga tatctttagc caaataagta gccagacttt taagatcttt 134760 actaaatgta actttaaaat gtttgatgtg aaccggtgta tgaatctcag agaacatact 134820 aagattaatc atcccaatgt aatagttaca ttgaccttcc acttcaacac ctccccaaag 134880 tccataggaa gctgtataag agccttctat ccattttcct tctaagtacc cgcctgtctt 134940 aaaagaaacg ttcttagggc gtttgaggaa cttatccgtg atactcggtt tatcagcttc 135000 taaacttttg gcaatgttag atcgaataat ctcaaagtgt ttgtaataga gatcttccgg 135060 atacttgcaa gcattcagtc tagtcatgat catattgatc tgagcttcgt taaacagatc 135120 acgaatacca gagagagaaa taatctcttt atcctgagta taaacatcag agatatggag 135180 agagtacttg tgttgtttat tacgaaccaa actaatctgg ttcttgcaca ctacaccaat 135240 tttaagttca aactctcctc gaacatttaa accagcaata gtttctttca gatgtttacg 135300 aacatagttg ttatacttca acagtggaag aaagaactga gaatacccca gttcacggaa 135360 atcttggatc aacgtataat taacatccat aaccgaatgt agtactgaca ttctttcaca 135420 tggactaaaa gttttcataa ctatttttcc tttctagatt acaggatgta tttgctcatg 135480 atgttaccaa taacaccatc agtgagtttc tcaggagtaa cttcagaaac cgacatatag 135540 atatcagggt tgtaattgtt gtagtaagtt ccaattccct tgatctcacc caggatatca 135600 aacttcaatg ttgagtcata gccgttaaag caagctactt ctttcaaagt gaacatttca 135660 ccaataattg gattgtccga tttaaagctc acagaaccac gtttaaacaa ctttgccaag 135720 aatccaggtc tttgcataga tccctctctc aagttactca caaagcgttg tagagcggtt 135780 ctgtaacgac tttcataagt aattacaaaa cgtttacgaa gatcattaga aatctcatca 135840 tgatccttag ttagcaagtt gattttaaat gaacaaccag agatagtagg aagacgttct 135900 ttttcaaact taacatctgc aaagccaaga taaacatcca tgtcctcaat aaccgcttga 135960 agtttgacat gaccacaagt aagaacatta atcttcttac cacgagaacc aatgagctca 136020 gtttctagag cttccagaat ctctttatca ctagcaaaga ggttaactac tcgagccata 136080 tccagaacag ctttatcaac gtgattaaat gcagttttca tttcctatac tccattggac 136140 agcaaaataa taacactgag aaggatctct ccctctcagc atgtctattt aacactctac 136200 gacgttttga acgtaatccg ttaccaacca acccagggac ttattaaatt ccttctgagt 136260 gaatacagtg gagatatcga taggtttgat cttgtcgata actagttcgc ctacaaaccc 136320 tcggcaaaac tttggactga tcttaaaaca caactccaag gaatattgac cataaacttt 136380 acgagcaata ctgcctttca catcaatgta attaccaaag tcttcatgag gtgtaaagac 136440 aacttctttc ttggtttcac gaatccgatc aaagagacca aactcaggaa cttgacacat 136500 gtagtcaaaa cccttgatgt actcacagac gtgatcgata tcgtgcttga agtctacccc 136560 agcccacgta atgaaaagag cttccagccg cccaacagtc ttcttattga aagcataaaa 136620 cccattggta agacgatctt taatcaaagg tgtacctaga ccctcgatat gaatccacca 136680 ggctttaccc tctttcacca agcgaacttc tacactccca atcccaccca aaagaacatt 136740 gtcgttattt ttaccatttg cccaaagaac caactcttta actttctcgt tgattacttc 136800 tacgtttttg gacataatct tcaaaataac ataaacaaac aacattttaa ttttcaaacc 136860 aatcgttccc attagaccaa tcccctgcta ttaacgtgtg aaattaacag ggagttacct 136920 ccctggatgt ttatcacata attaatagaa gatatcagaa agtgttacat aagcaccatt 136980 ccagtctgtt ttaatgttaa cagctgaacc atctacaaac tgaccacggt aactggtgaa 137040 ttcgtcttca tcctcttttc gaacgttaag ctcaaagtca gctgtaaagg acatagtgcg 137100 cttattgtac ccagttactt tataccccag agtgtaaaag aagttattgc ctcgagcttg 137160 agcttcctct ttccagaagt tgaaagtgtt gtgcatctgc tgacgtgctt cacgaccgat 137220 aatactttcc agaagtttac cagtgatgtc attacggtat tcaggatcat cagtaagttc 137280 aaaggtaaaa tcgtaataac ggattctaga agtaagttcg tccaacatcc cttctttact 137340 cctagtgaaa taaagaccgt cgagtttatc gatataaaaa ataaaatgct tctccccgtc 137400 gttaagtacg aaactaatac actcgacccg aaattcacac agtactctca tgtctttaat 137460 gagtttttga ttaacctgtt cttgtttaac atgagttaca gaaaacgcat tacgcagatt 137520 aagctgaaca cgtttcttga tttgatcaaa gttcatatac tacctctatc ctaagtcaat 137580 ttttacaagt tgattattga taaacccgta gttttcaggt tttgcgtcat gataccaaaa 137640 gtcagggtga agatctgaca acacagctaa tcttgttaac tctacccaga acaatccacg 137700 atgtcttact tccctgactc ttttgctaat aacacatatt cctagtttac taccataata 137760 cataggaacg agtcctaacc ggttatctaa gcccctggta aatctttcct ctgtaatgtt 137820 agccaacaga ccatgtagaa agagttccca agagcttaag gtggggattt taaccacaaa 137880 gtcattaaaa accaaaacag tcctagtaca ccccttacgg ttaatgaaca tcagtgatag 137940 acccccaaat ctagttttac caatcgaccg tatttatccc agccgtagtt aaagacctta 138000 gtgtcctcat cccacacaaa tttccactca tggtctttgt tgtaaactct ttccaagtgc 138060 ttgtagaacc tacagcgatg ttctttctcg tctttcactt cttggtaacg tttaaccacc 138120 aagattattc caaacaaacc agaccacttg atttccataa cttggtcagg aaataaccca 138180 tcgtaagatc ttaccgtttc gatttccttt aagttagaac acagacctct tacgaacgac 138240 aaccagcttt cagttctagg aagtttaata acaaaatcct taaacacgaa aacttgtcga 138300 tctctcccac ttactttttc ctcacaacca aatagcctca taaactaccc tctctacact 138360 caaggttaaa attaaacctc actagtttat cattaaaata atatctatct gaaaaaatat 138420 gggacttaaa tattttttat ttactaccaa gtatttatta tatgtgaaag aaaaacccca 138480 gcctgttgtc agtggatgtt tttcatgatc ggatcctcaa tgatgtattt ataccggttt 138540 ggtttaaggt aatggattat attatttgtt accttatttc tttaagttta ttccaattaa 138600 gtgaacttaa agaagttcag gctgccgcta acagttgact tcttgcattt caaatcctcc 138660 gtaataaaag gtcacaggta ttctcctcct agatatctgt gactttctta atgattattc 138720 ccaatgagtt gtcattaaga aagtgctccc ttactttcat gtacgtttag gtgcttgtta 138780 ctcagagaag gttttatccc accttctctt ccttaagagt attattagtt agtattctta 138840 aggaagaacc ccgtgttctt cgtacgctgg tttgcgtttt ctttttcatt gttttgttct 138900 atttcttaga tgctcaattt tgtaggtgtt aagtcgacac ctacttttta attagttttt 138960 actaagagtt aattaaaaag taatgagccg ttcaaaaatg cttccatgcg tttttgtttt 139020 actcctagtt actccaacta actaggagta tttttattta ataagcataa tgtttatatt 139080 atgttgaagt atagtagacg taaatagtta atctagttac tcgacttaga gatgttagta 139140 gactgaacag aagtcgcttg gtgaacttac cactaggaga tgccggtata aagtccggtc 139200 taacatctcg cccctatttc aaagaacatt attacttccg aatctaccac ttgataattt 139260 caaccctaaa ccgggtcgga catttgcgca ccttggggat agaacgaagt aatacatgtc 139320 gggtaggata tttcctaccc acctattcag agctcgtaat tcagttggat agaatagaag 139380 ccttctaagc ttcctgtcgt gcgttcaagt cgcaccgagc tcaccatttt acagggtctt 139440 tagctcagcg gttagagctc cgagctcata actcggcggt cgttggatca tacccaacaa 139500 gactcaccat tttagatctt tctcaagaaa cttgtccatc taacatttac ccgacaaatt 139560 acactttgac tcgaattgaa gtgaccgagg taaataaaca atatgagacc tattggtatt 139620 catgacgaca aagagaaaga tctaaccttt ttatgcgagt ttggtgaaat cggtagacac 139680 atctgtttta agcacagacg cttttggcgt gccagttcga gtctggcaac tcgcacgaat 139740 acctagttat ccatgtttga ttttagacct cccgttgctt catgctccat cacaaattgt 139800 tgaaactcaa agccttgcag aaaagttaaa actctcatgg ataactaacc cttttacgaa 139860 ctatcaggtt tctaattaac catctgcgtt aagtggagcg ggcaactgat agttcaacct 139920 ttcggtcact acttagaaat tcgcagaacc aattgcaaaa gtcctcactt acccaatgtc 139980 tgttaattca aaagtagtga tcgtcctagt agtctcttaa ttgtttcccg ttgttataat 140040 gctcggtcag catatctcct ttatcctaac ggtgcattca aacagttaag aggcgtccaa 140100 atccctacgt ggcgggatcg tcccaaatag ataacctcag gacgcaaaac aaagaggtgt 140160 tgcctttcag acgaaacgta aagctgttta agcagcaaat aagtctgaaa gttatagtcg 140220 aagtaagacc gcgacatgaa acaaagatgt ccagaacgac tcaggtcaat ttagatctga 140280 cttgttcgct atttaggaac gccctaacag tgagttccga cactctgtac ctgcgggtat 140340 ggtcggtgtt ttagacagcg cagacgttag tgacctagag tataaagact agatcttttt 140400 actagacgac tagaactaac agagcaaact gtatgctacc tttcgtcggg tagaagtggt 140460 gtagtaaaat gcacgacctg tagggttatc ttgaatacca tttaccgaag cactcggtat 140520 ggaagattga taaccttatg gaatgtgtat tctcgcacat ttaactttga tgttaactac 140580 agataagttt actctacctt cccttaattg ggaaggtaga gggttatgtt tgtcctgcgg 140640 gggattttga tcttttgtaa cttcctaaaa gtaacctaat tagaaggaaa tgggatatga 140700 acccggtaga cttttctatt cagaatttaa tatcaggagt caacgatatt cctgaatatt 140760 tgcttaaatt agcgtttgat aatcctaata acggttttgg atctgtatgg tctcctgtta 140820 atactgaata cagtattgaa caaggtattc gtgagaaagt tatattaaaa atggtagcgc 140880 cgctgataaa cgttgcgggt ggttctaccg agactttgga cttgagttca gctagaataa 140940 caaacttaca atctggtcat atagctgtaa atgtacccga cttcttaact ggtggtagaa 141000 agattatttc agttattgaa gtctatcctg gtaaccttaa tcgtgctatt gcttctggat 141060 ataacatgac aagtgggaat ggttcttgcg gaagcggcgg tcaagttggt aacgcactga 141120 atcgtcttat ggctggattg gatgacagta acgttcagcg ctcatttact agtttcacta 141180 tgactggtaa taactcattc atcatacgtg acgctggcgc agcgatgttt aatatgatcg 141240 ctaaagtaat cttagcttat gacgaacatt tctcagtaat cccacctaag atgtacgata 141300 agttctacga gcttgtagaa ctagctacaa aggcttatat ctataagact tgccgtaggg 141360 gtatgcaaga agcggtatca cgctacggtg tatctgtgga cgatgtaaga gatgatgtag 141420 aaagatacgc agattcagct agagagttca aagagttctt caacgaagaa ttaaagaaac 141480 atctcgctta cgcggacccc aaaggtgtta gcgataccct taagtctctt gtgccaagaa 141540 aacgttaatg gagaaggatt aaatgaatca atttagtcat caggttcaag ctagatttaa 141600 tcctgaacct ttagaagaaa cagattacga taatagcttt ttagagctac aggaagtcct 141660 tagtaaactt tctggtagtg aggagtatct cagctcaatg tttgcccctg ttaggtctat 141720 aaccgaatac ggtggtttag agagctttga ggatattgcc gaatgtattg ctggtttaga 141780 agctttagta ccaaattaca actataacac tgaccattca gtttatggtg tttttgaagg 141840 actagtagaa gacttagaga tcacacctaa atgggtttct acacttagac gttttgtcta 141900 tggttttgca actaaggata atgatcacgc tgagttcttc ggtacaccat atcttggtac 141960 acatcgtatt gtatttaaaa ctgctgatcg cgtagctttc tttactgaca tcattgatgt 142020 tgatgaagtt aaacttcgag atgaattgat caaatgtaaa tggattaata aagactttaa 142080 ggtatcttcg gatgccttta acttatccat tgtttatttg atgcataaag ttcacaagtc 142140 taacttacct aagaacatga aagatgatgc tttagtgaat ttgatcattc tgtttcacta 142200 tcgtatctta acatctatca tgaaccacta tttcgcttac ttggtaaaac ctagtgtcgc 142260 tcaaactgca tataacaaac tgtcaatgaa gtttgacatc aaacgttacg gtagttggaa 142320 tgctctgttt aaagcacgtg ctgaattcat tattgatcct aaaactggga ttcactacga 142380 cacttttacc aagatggaca atgataagaa aattgtctat atggtaaacg atatggaatc 142440 tcgtttgaaa ggtgttgtta atgatttcac taaagtactt tatgaagtaa aggatagtgt 142500 taacttggta gaaaccgaat caggttttgt gattagtgat ggtcagattg acctgaaaga 142560 catccagaaa aatgtaaacg cttttcgtac ttacatcaat accattatca ctgatggaca 142620 ttctttctac aaacaagaac tattgggttt tgctgctaaa gcaatcgatg actctaaagc 142680 acagaaacag tttgaagata aactagcttt agtagttaaa gagtttccca ctcagtataa 142740 tcatccaaag ggtgagaaat acagagagtt tgtagatgat gttattactc acctttttga 142800 gtatttgagt tctaactcta ttcgttataa tgacttgagt aacgtagtat ataagttacg 142860 cggtggttac actagtaaca agtcagttaa tgaattggtt cataaactta gaaagaatgg 142920 tgataagttg atcacttcta tgactggtat taaaactcag tatagcgtag cttgtttacg 142980 gaatggattg atgttgtaca ttgtaattag aacattagtg cgcgactatt ataaataaag 143040 gagatgagtg tgggattata tatcgtattc gaagggatgg aaatggcggg gaagtcaact 143100 gtatgtaaaa agctgggtgc cgctattaaa gcacgagtta cagcagagcc tttcaatgaa 143160 actcctgaga gtaaagcatt taaagcaaag ctagttagca acacaatgac caaggatgaa 143220 gagatccaag gatttggaac agcacgagta gaagcctttc aaaaggtcat tgatccttat 143280 ttgaaacacg gtcgagatgt aatcagtgat cgtaacttta tcacttccat ggtttatcaa 143340 tctgatgaac atgttacacc aagtgagatc tttagtttca ataggaagtt attggaaact 143400 tatggatttg acattattcc tgatttagtg atctttattg atatttctca tgaagagttc 143460 ctggaacgtt tagataaatc tattaaagat ggtcgggaga ttaatgctaa agatctgatg 143520 tttaaagata aggaagtgtt tgattcctat cgaaataaat acctgaggtg tctggatcat 143580 cttgttgatc aatatgaagt aaatgttcag attgtcgaat ctaacgaaac cgatttagta 143640 aatcttcttg atattgttga aaagagtaaa ctattaaaag aagaaaagaa acacaagaat 143700 aaaatgagta aatattttca agtagtgtaa agaccttctc cacctatttg ggtggagaag 143760 gtaaattaag gataaagaac cgaacttatt tttttagatg tactactacc catggaaccg 143820 ccatcaataa ctgtgttaac cgctgtatcc atccatgaga aagaatttgg cgttcctcca 143880 ttatgttgaa gttcacaccg taattcagaa tttatcaccg ttagtattgc agtcccaact 143940 ttcttatact taacgccaag caaagtcccg cctataaaag ctcctccttc tatatggaca 144000 cggatagaac ctaaacacgg tattagtggg cggtaatcac tattaacggt ctgaatgttt 144060 attgtcttta tatttttaat agttaaatta cttatcccgt tagggagaga atggagttca 144120 ttatatgttt gacctacagt caaaacctcg ttcccagttc cgagtaacgt taaggaattt 144180 atttttacca gcttagtggt gacgttcccg ccttcacgat agttgtactt tgtaccaaca 144240 ttgccagtaa aattaaaaat attatctgct gaattgttgc acctgtctat tgcttcctgg 144300 agtgttaaaa ccggataatc cttgtgataa ccagtattat tatcattacc agtttcagag 144360 acatatatat ctagtttacc attagatata tacccagtat aatccactct agaattgaac 144420 ggtagggatg ctatacgatc taaacctgat aaaaccctta cttttgagta ttggtctatt 144480 tccccaatgg tgtccttttt aacactaaaa tagctacagt gacctagatc caaatctagc 144540 ttacatgcag tcaaatggaa taggtttccg ccactgatta aaacccaatg tagagataat 144600 ttaatagcta ccgtgtgtgc tgctaatata tacttatatt taccgccctc tatgtaatta 144660 tcctcaagat gcatggaacc ggcatttgta gtcatgcacc ctatttcggc accctcccat 144720 atattatcac gatgttcagg atgaccataa ctattatata cgttacaggt cataccaatc 144780 aactcagtag tgggaaactt agggtaatcg aattcctctg ctgtgggttt ggtacctagc 144840 acacttaaat aattatgttt ttggtaatct atagtggtgt cattggcatt gtataaacag 144900 atagctctag cggcgatatg attatacatc accgagccgc cccaactaac tgatgtcctt 144960 ataccaatat tggcaccttt aaaactacag tgatggatgt gagattgctg agagttataa 145020 cggttcaaca ctcccatgat atttcttccg tcgggaacga taacatttaa cccgtataaa 145080 aatacaccca tacaacctgt gtaattacca tcatcccagt cgccccttgc cccagttcta 145140 cctaaaattc gtgtaccggt tttgtcgtaa ggcgcagtat ccaaaacaaa tccatttggg 145200 gagtcaaaat cagctataat aacaaaccca gattcactat caaagaaacc acctgttttg 145260 tctatcacaa tagacaaaaa tggagagagt ttaagagggc gcgttattct aaattttcca 145320 atccctgata caatcgctct tattctacct aggtaacgtt tagtctcgga tactgatccc 145380 ctccagtcaa acggtgcgca atagtctata caagcctgca gtgcatctgt ggagtccaaa 145440 acacctgtag gatcggcgcc gccagcaaat cttttttcta caggtgaaac ccttgttaac 145500 cccagtaatt tgtttttaat ttcctctgtt cgattaccta aggcctcagc ttgaaggttt 145560 aaagccccac cttctccacc tacaccttca cttacgttca ttggaacgtc tgaccattct 145620 ggtttgaatg ttaaagtccc actaaagtca ttgatctcat tccgcaaagc catagaacgt 145680 ttaatcaatc cagccaacgt taaacgtttc gtaccgaaac gatcaggatg ttcatcaagt 145740 tgactattgg caaagtaatc aatattctct gagttatcgt aaagatcaag gatgtctttt 145800 gacccaagtg ggtttccggt gttatgcata ttctttatcc ctttaaagat taattaggaa 145860 gagtcataaa atcagtaaaa taaataatat aaaataactc tacttactcc ttaggagtaa 145920 gtagagttta attaaattaa attataaaac tataacacaa agttatcaac caaggaatac 145980 caaaattcat tagtcctttc ttagtccaag ctctttcctc aagaccacaa taccaaggag 146040 catttactct attattaccg tagtattgtg agatcaccct ttgttcagct tgagcgacct 146100 ctctcccgat aaagaaacac gccggtataa tgtataaatc attaaggtct gtaacataac 146160 aaaacagtaa ccaaacgact gttatcaatc catgaatcat attagcacct tatctattaa 146220 aacgtctatt gatggcacgt ttactacgtt cggcagaagc attgctaatg atttcgtcaa 146280 tggtcagtac acgtttgaga ctcttaggaa tgaattctcc caatttacgt atctctaact 146340 caatgcgctt acctaccata tcagaatcac tatcttctag ttctttactt aactgttcaa 146400 tacgttcctt aatcaacata aacaattcta gctgatcttt ggtgtagttc tcgccatctt 146460 gactaccagt taaagtagag atctgagtta aagcttgacc aggaggaata ccgtacagtg 146520 aactattctt caacatacga atagcccagt aacttaacaa ccaagcaatt accaagtcgt 146580 cgtgaccttt cttaccgtga tcgatgcgac catccatatc agtttccaaa ccaattagtt 146640 cgtcaaccaa atgaccgtat cgaataccac taccagtatt actcacagct tccaaaataa 146700 acccatacat ttgtctacga gtttcagcat tagttaagaa tccaaatcta gctttatgtt 146760 tcaaataaaa ctctttagtt ctaaacttaa acattacctc ttgaacgtca cgatattcat 146820 ttttatattt aataggatct tgataaatat cattgaatat acgcttaaaa ggatctattc 146880 cgtaacttgg taaagtcaat aacagttgtt cgatcatgtg cgcggcacgg ttacgttcaa 146940 taatcaataa agagttttca atcctcaaga tcatctcacg taatacagtt gtaacatcat 147000 ccaagaaagc taacggatac ctacctaccc caatgttctc accagtcttc atacgtctta 147060 atactaatgt acaagcatcc ttgttaatag catcagatgt atcgacgccc atcaagataa 147120 actctgttgg atcatttact aattcgtcta atctctcctt agtgacaaac caatccacaa 147180 ataagccagt atcatttatc tcctcattcc aaatcggttc gactttacta tcgttaagtt 147240 tctcccgagt tttgtcatca aagagtttat tttttccttc ttctgaccac atgaggagca 147300 agtcgatttt agccttagcc cagctcaaac ctaacttatc cattgtgcgt ttaacccaat 147360 catgcccaaa ccccaattgt aaatggttaa actgcattgc aaatttagga taagtggttt 147420 tcactggaga agccttcata accttctcta ccagatgtgt ctcactataa cagtcaaaga 147480 acacttccct ccactctgta cttcccagca tctcctcatg catatacttg ccttcatctt 147540 tcaatatgct gttaggagtt gttgctttgg ctgtgaagta aggaatacct ttttcccgag 147600 cgtttttctg agcagtcaat gtactaggac cggcgccgtt tataatgttc tcgatgtact 147660 tagtccaagc tggctcatca tacaacagcg tttcgaatgt gttaccacga gatacgtttt 147720 ctgcaccatc ttcaccacca ctaggaacct ttacttcaaa ggtgttttcc ttatcttgac 147780 caaaagcttg ataagagaga atgttaccag catccttgtc cttgtagttc atgttaatca 147840 tgtactcagg aagtccagca cgaatcttct taagagcatt aatgaactgc atacggttag 147900 aagcagcgag tgtaataaga ccactacgat aaccacgacc tatgatatac tgcaatatga 147960 aagccattac ctgcatacca acagtgttgt gcgttactac aaagtcatcc acaatgtaca 148020 gctgatcagg gtggtcaatc tcaatacaaa tggtctcagc ctgctcagga agcttctcaa 148080 cagagtagat agctaactta ctgttaaaca ccaaccccct tgtacagttc tgtacacgtt 148140 ccttacgctt aggatcttgg aataagttcc acggttccct actacgaata agaactctat 148200 aacttggttg acctggttta cgcactcctt tatgagtgta atacttctgc tctttcttaa 148260 tcctagcaat attacctaag cttctagcta agtataaaac atcattagct agttgttcat 148320 tactagtaga gtagtaagta tttcctccct tctcagcagt cccgtctgta tccattagtc 148380 cttgtaatag acgaagacgt tgaccgtgag aagctaactt ataacactca ggaataaact 148440 tagtgaaagt gttagtccca tgtagtctaa gttctcgtaa cagatcctgt atagacctgt 148500 ctttactagg gtcgaaatca ggacctctca caacaccgaa acgtttaact gtcgcatgtt 148560 gagatattac gtaaccctta ggtaaaacct ttgaaactct tttttgtagt tcaggatcag 148620 gtttcgtaat agaaacacta ttctgtccta tcgatccatc tccaagtagc acacctaaca 148680 aataaggatg tatcggtagg ttagctgggg gagtggtttt atctgggtct acgaggggaa 148740 cagataagtg gtttctggct ctttttaact ctggtattct ctccattata gcaagagtat 148800 ccatcacccg ccatttccca cgatgtcctt taccagcgtc ccaaactgtc caaagatgtt 148860 cagctgtaca atcggctgtt ctgccgtcga caaaatgaac acgatagata tcttcagcat 148920 cctggggata aatacctgtg acttttgaca atgttccatc tttagccgtt acgtcatcac 148980 ctacttgtaa atcttctact ttacgccatc caccagggat tttaatagtg cattcccttc 149040 ttacacattt tcccgattgg cgtggcatca atattagtgt tgggatatgg tttaaacagg 149100 cccagataaa agagataaca gctctatttc cttggaaacg tcttccatca attttgatca 149160 attcccttaa cgtgtaccaa atgttgtttt gcgattcttc taacaccatg aacttttgtt 149220 catcagttag attcggatcc catgggtcta cgtctttgag taacgggtta ttgagttgaa 149280 gcataaagaa atagttctta atgcccattt gtctaaatag ttcagctgtc cttaaaaacg 149340 ttttgttagt cgtctctaaa tgaatacccg ccccaaatct tgagaagtct tttaaaaatc 149400 tgactgttct aagtgtgggc atcgactcgt catcataatg agcaagaatg cgttcatcta 149460 aatcagcaca aggtatctgt ttagagtaag catctgtaac aaagtcaggt aatgtctcgg 149520 gttttatacc caagtgatta agtatcgact tagccgtatt aagtttatct tgatccattg 149580 gtaaatccta gtttagaata tattacttca ccagagtgtc ttggtttcca tagcatctac 149640 tatgaagttt taaagaataa ataaataata tattagaacc ctctactccc aattgggagt 149700 agagggtaat ctagttacgc ttccagtacc ggaagttcag ttccttcgat cagagccagc 149760 tcagtagtat cgtcttgcag ttccaaggaa ggaagatact tgtcagcacc aaacttcaaa 149820 ctgtgagctg tcaaaccacc aaccagagca cccatggctg cgtgagaagc aatacctgag 149880 taggtaccaa gtttctcatt cagaccagct ttagctgcac cgaaagatgc ggcagcggcc 149940 agagtaacag cagcaccagt gattacgttg gaggtcatat cgaaacggtt ttcaacatac 150000 tgaataccca gacatgtccc cagtgctgca ccagcagcta ccagcacccc agtggttaca 150060 ccgataccaa ggttagaagt atcggtggat acagcaggag ctgcgttgtt catgtcagag 150120 ttcagattca gagcagatgc agtttgagtc attttgggtt cttccttaat ttgattagct 150180 tcgggttgtg cttgttcatt ggtaacagtg atcttgatca ctttatcttt aggagccatt 150240 tctttctcct caccttgatc tacaatggcg ggttcagatt caacaacagg ttgaactttg 150300 aaccgctcac aaatgtactt ccagccatcc agttcaatag ctgaatgacc gacattatcg 150360 tgtaacttct ggattccgtt aagagcccag gtagtgctgc tatcagaata acgttgaaag 150420 ataaatcctt caccttttat catgataaca tgacgaccgt gatcgtcaat ggccaaagct 150480 actttgtgac cttgggtaga gatttcactc cagtggtcat agtaatctgt agccccgctg 150540 gcttgttgcc actcagcatc gctgatctga agaaccggtt tccctttagc ttcaaaagct 150600 ttccaaacat ccatgccagt tacgttagcc ggaacttcga ttttaacttg tttgttcatt 150660 ttacattccc tctatactta ggagttaaag aagattaaga attatcttct atgtttatac 150720 actatagtaa tataggtttg aaaatctatg gatcttaaat actttgtatt tacctaaatt 150780 aactaaatgg aaataaaata atgaatgtta atattgataa tcttgaacat gttttaagta 150840 ctttgaatgg gtttgaatct ttgagttctg gtgatttaga atcaccagat tctatttatg 150900 ctaaaacagt tcttaaactc aatggtgttg attttaaaca ccgagccgga accgaaggat 150960 ttatgtcttc tgttaaagct ggtgcacaga aagtttatga aatgatcaaa aactttatta 151020 aagctattag agatttcttc tttggtatgt ttggtaaaaa agtagatcaa gctgtgtcaa 151080 acgctattcc agaagctgaa aaggctatca agagtatcga ggttaatctc aataaaacgg 151140 acattaatga atctaccaag cgagaaatag aggggactat tgaaagtatt aagaatactt 151200 ttaatcaaat taaagtttcc ggtgttgata aagttgtcgc cgaaaagaaa attgaaaaac 151260 ttgctagtaa aggaaatgac acacaaagtt accgttttga tgaaaaagaa gaatggaacg 151320 gaagcgtaaa ggtcaaaatc aacgaacttc taatttgcga taaaactaaa tttaaagaag 151380 cgattaagta tatcgataaa atcgcagaag actatggaat gaaacatcta ggtgcaagtt 151440 ctgaatttat agatattaga gatcattatg aagaactaaa aataagcaac gataaggata 151500 cttttgaatt tgtcgtggat aatctcaaaa cagccaagaa cgttttgttt acgctaaata 151560 agattaatgt ttcggctggt gattgtattg gtgttcttaa caatcttctt gagaaaatta 151620 atgaacagtc gagagtagat caatccaaga cagatctgac aaagacagca atcgcaacag 151680 atcgtttggt gatttttaat tttatacaat ctatgaccca gcttaaagca aaatactcaa 151740 agatcgcatt aagtattaac aataaaatca ctaagataca agtccttgta actggtgatg 151800 gacagaccga acagagcaaa cgtgttaatc aagaagcaat ggaagcttta gcgcacattc 151860 cagaataaac aaacatatag ttaactctag acctcacggt ctagagttaa cttattatgt 151920 attaagagta aaccactact ttcttgcaca caccggcaga tacaccaagc tgtagttcat 151980 tacctgacat ctcacgacga gtccaacgaa gatatacacc ttcgccatta ctaaatgaca 152040 agtcgcctac tggaatgtta ttaaactcac caataggaat acctgttcta gcagtgttgt 152100 tattcttcac cagatcaaag tgtgttggaa caagagcttt actctcagta cgtggatcat 152160 agattggatc aaacccatag taagccttgt tcaagaagtc ttccaaagaa gccatcccag 152220 caaacttagc aatttgagtt ccacctacct gttcaatata ctcaacagac aaggcgctaa 152280 aagcaggttt gccataagaa tgacgaacat cccacttgcg accttctact gttccatcag 152340 agtacaatgt gatggtagtg tgttggacaa acgaccaagg ttcataactg gcagaaacat 152400 cacgcatatt caagttgaaa ataaggttct gttcttcacc gtatttacga ccatcgaatg 152460 caggacttgc ttcattcaaa gtgaccagtt gtgtaacatc tcgacaatac cgccgatcca 152520 gatcagtaag ccaatgacga agcttccacc cagcagcagg atcccaataa gggtaactgt 152580 aaatacgagg actataactg ccctgagcag tcgtcgcaac aatcgtataa cggtttgacg 152640 tatgcttggg agaacccggc tgcgcgatat aagcttgctc attatttttg taagcataag 152700 acaataccag cgcattagtg gattgaccag gagtagttgg cttgtattgt tccaaccctg 152760 acaaagtaaa tccagattca ccattaaaac tgtttactgg atgttcttcg taactaccat 152820 cagagtagtg gactttagct ctaaactcaa ctaccttcaa agccaagtta attggaatga 152880 acaaggtatt cggtaaagta gagttagtaa accaaggtga aaccagttca atagatttaa 152940 cgtaacgttg acctagttga tgatctttca gataagcact gtgttgtact gctactgaat 153000 aggtaggtgg aataggtctc ccagctacat cgtagtaaac taaagtacaa cgtttaccat 153060 tcggcatcgc agcttcattg agttgaactg agaaactatc agcacccatg atggtcttat 153120 tctccaagtt gtcaataaca acaggagaaa cagagatgtg gttatctact agatcagacc 153180 ccgaatatct agcagagata atcttaccag cttcaccaat caccgaacct tcatacaaca 153240 gcgcgtaagc tgcatcaggt gcagttgcgt tagcatccac cctagctact ggcggacgaa 153300 cactgtaatc gatacagagt gctaattcac cctgtaggaa tccgtattcg tgcttaggga 153360 acaaagagta atcattctca ttagtttctg gaattggata ccaaggtaca aaagtacttt 153420 tccaagttcc gtaacgatct acatgagaaa cttcgtaaaa cttgtgagcg ggacgatcaa 153480 ttacgatcgt accttcacat ggaaccatat acttagaaat atcctcgacc ggatgaacat 153540 cagggtcgta aacgttttca atgtataaga ctcgtttaat ttcatcggca tttagaatat 153600 taggagtgtt accagggaac actcctttag tatctggaat cgttggttgt ccatcaaaca 153660 ttagacgata cctcaaagaa accttcaatc ttcaacttac catcgagata caaatcgtta 153720 actcgagaga taattgttaa ttgattagga gtaacagttg gacgagtaag attactgtag 153780 ggatgaaccg agaagaatct caaatccatg ttaagtttaa ttggatcaaa cttcaacaac 153840 cattgataag gacgagttaa attatcaatt aaactatctg gatatttaat cggagtatca 153900 ctaggtgtgg gagttggtaa gaaacctaag atcaattcat ttacaatttg acttaagaat 153960 ggactaaaga gtctataacg atcttcctga agatacggat aattaacagg agctttaggt 154020 ttgtacttaa cgtgttctgt caagtagtca ctaactttct tatcaagctc tctggattca 154080 ttaaatcccc aatgtaaatc acactgttca acatacttgt tatcacagta gatgtgtttt 154140 acttcgtaag gaaacccgtt caacacagct gcattagttc cgtgatgaat atcttcagct 154200 tgatcaatcg cagaggtgat ccaaagtcta ccattaataa tagtctttgt aggacgatca 154260 atacgaaggt tatatcgacc gttgtaacca attaccccat ccattacaaa tcccagctca 154320 ctagaaggaa tcaaaccacc tgcgctgagt cctcgtccac gataagcaaa cttgtttgta 154380 ccagattgat ctaaccacat cttagagata atgtaaacat aaggatattc aaccttatag 154440 tccacgttct caatcaatgg atgtccatta caccagacat cgagttgacc aggttccata 154500 gtggctagaa caccacctat ttcccactgg tgagtgatac caaagtaaat ggagttatca 154560 acatgtgtta gatcaaattc gttatacaaa tgaatggtat caaagataac taatccaacg 154620 tggttattag tatcaaactt ccatttaaca acaccgccga taacttggta ttcatcacta 154680 tcagtaatat ctatccactt accatccggt ctacctgtgg tcacaggacc aactggatta 154740 gctaatgtta aatcaccacc aatactcaac tctgtgggag taggatagat gtcattacca 154800 tcagaagtaa tagctacttc attagcaaac aagctagtgt taggagtagg atctggattt 154860 tcatcgataa tccatcctgc tttaaatacc ctgaaaccat aaccaggtct agcttggaca 154920 tctactctgc tgatttcata gtctaaccaa gtacttgctt gacctactac aaactccaca 154980 tagtaagtat cttgacctgg tttaaaccat tcactattac gaatagaacg cttacggata 155040 tataatccat ctttgttata ttcatacgct gtagatgatt caacataact agcaggaata 155100 cgatatccta atccagaagt gtaaggtggg gttgggaaga tatcttcaaa gccaggatca 155160 ccaggggtaa taaacggcat atacagaggt gaattagaca gagctgtaga acaaccattg 155220 taacctaaag catctcttac acgttcagtg gtaatctttg gtgcaataga gttaagtaca 155280 tagttacaag gtgttttctc cagttcacta ggtgtccact cttttacagt agcgtgtggt 155340 ccaatcatcg cttgaagaat aacagctgga tcttccagta agtaaagatc attaatacga 155400 ctggtattag gacctagatt aaattgccac ttggtatctc tgtaacgaac tacaacatcg 155460 aaatcattct cagttgcttt acctttactc aacccaataa gttcgctaat caagaaactt 155520 acatagtcag aagttaaccc ataatcctga tgggttaact gtctaatagc gtcttgacta 155580 ttacgatgat aatacaaacc ttccccagtt aaccgattaa ctacgaagaa ctcgcaatca 155640 tcaaagtaat ggtatttacg aggtttatca gtaaaccctg ggaatatcaa tagttttcgc 155700 ttactgtctt tctcagagta atagtcattc aaactaccgt actggtactt tacttccatt 155760 ttgatagttg gatcgtagta aacttctaac agatcaccaa tacgaccaac atacctacca 155820 atgtcagtaa taacaccatt tacaaagaaa gtgactttcc caataccata agctaagtaa 155880 gcgttgtaat gattcttcaa attggttaaa tcggaaccag ttacaaactc taccccagag 155940 taaccaaatc gccatttgac ttgctggtcg cttggaatga tcgcggtatt tatatctgtc 156000 gtgtaacaac gaatatacat gttactacta acaggaattg gataattacc attaataggg 156060 aatgctacaa aagtgttccc ctcgaaggtg tttaaaatat aggtatgagt tcttggaaag 156120 attctacctt tgctattata aacatccagc ccaacaccac gatcatgaga gatggtggaa 156180 gctttcaccc aagtattaaa cggataccag tgattacctc gactacccat attccagtag 156240 tcgaggtcta aaccacccat tgaaaagata tgataaaaca caccttcact cggtagtgta 156300 aacgacttcc ccatatagaa gaaattattc acataaccaa gtgctggaga aacccgagca 156360 agcttaagtt gatattgaga atccagttct ggattacccc acatcgtgtt aaatgcataa 156420 tcgacaagtg gattattctc ctgggtgtgc gaagcaacat aagctgtcat ggattacccc 156480 agttgattag gcggatttaa aataatatcc aacagtacta atgaaggtct ctacacgttt 156540 gtcttgcttt acgttcaact cttcaccaat catagtgttt tgataaatac gttgagtagc 156600 ggcaccccag cacagcgcag tgaacagtgc tggcatctct agtgcagcac ccatgagttg 156660 tttaaaccca gaggtagaaa agaagatggt ggtgccagct tgtaccagcc ctggaagatc 156720 caaacgagaa agagattgca aagcaggatg agtggtcaaa gctttcagta gttctgggag 156780 agtgttaaca aaacccaaat ctttgattgt ctcttgaata aatggaatag gtaaacgcag 156840 cgcaccatga atgctgttct gggctacgaa tgcaaagtca tctcgactat tttccagaag 156900 acaaacataa taataagcta ggatgacacg aaccaccata gattgattca tgtccaacat 156960 taccatccgt tccagcttac gacccattgc attagcaaat gctttgatag taaatggacg 157020 aacagatttg atcaaagtag tttgattgtt ttgcagatct tgttgtaaac aagcagctaa 157080 caacatgaca ttatattcgg gaagattaac gtttctacct tccttattaa tgtatggacg 157140 ttgatcaaaa atagttacct tttcacgcat gtagttctgc gtagaaatag ggaagataaa 157200 aggagggaga ttgtaatcat ttttgtgaga gatcgcgtaa accccacgtt gatccaccaa 157260 ctccaattta tcactacttt ggagcatccg aatggtttca gttgctttgt cttttacttt 157320 aaaacgacta ccgactgtgg tgtcgtaacc atttataatc ataggtctag tcccaaaata 157380 atgttatgcg tattaacgtt aaaccatcta gtggccgtaa ggtcatacga ttgatttttt 157440 tgatcaaaaa aatccaacat aatttcggag tcgagtatga ctacttttaa taaagtgatt 157500 ccgggaaaag tggtaaacga aggtattgtt agcaaagaaa atcttactaa tccaatcccc 157560 gttttcgcct ctcctgctca ctttcctgac ttcgctatgg tcacccctcg gggcccgact 157620 aaacgcgata cagtcgcggt cgctgacttc aaagagaagt tcggtgatgt aatggatcct 157680 tatggtccgt tttataaccc gatcgcggtg gctattcaaa agcttgggtc tgcagcgcaa 157740 gcttctttca gctttaagcg tctcaccaat aacgtcgaag tagcgcgtac tattctcggg 157800 gttgttctct tcgaaggtgt tcctgttcct aactacgaac gtgatacccg tgatgactat 157860 gttcctgaca ttgcaggtaa tccgaaggta gatgaagaca ctcctactgt tccaggtatc 157920 tttgtttctc cggcaactat gtttgttgat caagctacag ctgtaggtga agttaagagt 157980 ttcgaagtta ctgcacctgc tggtaaatca gtacctgctg aaaccaaagg tatgttctat 158040 ccgttgtttg aactactctc cggtatcggt gatagttaca acgcgatgta cgcagctatt 158100 gggcactctt ttggtactga ctggaatgag attgcacgtt ttgtaatcaa ctacggcgca 158160 tacccgttca ccatgaacat tggcgagctg ctccccagtg gtatccgcgt accggcaact 158220 actactatcg gttctcccga ttccatgatt accctgttca atagcgttgg cggtaacaac 158280 gttcgctatt cagtacaagg tggtctggat cgtttcaccg gtcgtcaagt aaaccgtcca 158340 gtagaagata aagcagcgcc gtttgaatct gcacatgttt ataccaacta tctgaacgat 158400 gtttgtacta aactctacgc agctgaatac ggtgatggta aacaaactcc tccggtgatc 158460 aagaccgatg tccttcccaa aggcgcgatc atgaacccgc tgagcctggt taaccattat 158520 ggtaagaact atcaccacat cgtcttcggt ggcttggtgg atgttccttc caagctcaaa 158580 ggtactcggg tcggtctgaa tagttacctg caagctaatg gtggtattaa cccctatgct 158640 gataagactg gtaagtatcc ggacgcgcct gccgactgga ctaccgaagt tgatggtacc 158700 tgggttgcta atgtcagctc tccggctatt gtaagtcata agcaatattg gtacatgaac 158760 caatctctgc tggaagctta ctttgtttct taccgtcgtt ctttggatgt caaagacgtc 158820 attcgtaacc gcacttcctt tatgtgggac gttggttata atgaagcggt taaagaagca 158880 ctgatcgatt tcctgggtgt tcgtaaagat atcatcgttg tactgtgcgc aactgaatat 158940 ctgaagaaga aatctcaaga gcaactctat tccactatgg aatctttgaa ctctaagatt 159000 gtcatgtatc cggaatctga aaccttccaa tctcatgctt gtcgcgcagc gattaacatg 159060 tgggattgtc gtatcatcga tgaaccgact ttcggtcgct tctctttgaa tatcgatacc 159120 atgtatgcat ttgcttatgc aggtggtggt aacgatggca agatctacgg tgatcggatg 159180 ccagatcacg aaggtaaccg cactctgcgt gttgctcatg atccactggt tcagtttgaa 159240 gatgatgatc cggctgctaa taacctcacc aaaggtgcta tctcggtaac tcctttgaac 159300 acttctcagt attgccgacc agccctcccg actgtctacg ataacactga ctctgtactg 159360 aaagatcttt ccaacgtttg gaaatgtgtc tgtgtggaga aagtacttca agacacttgg 159420 atcaagatct ccggtgacac tcagtatcgt caacaaggtt atattgcctt tgttaaagat 159480 actgctgaga aagatatccg tgagaagttt ggttctgtca ttgttaactg ggaagttgat 159540 ccaggtttcc gggaagatga acctaacggt aaatctgtca tgtacacgac tactcgtctg 159600 tggttctcca aaggagttta tatgatgaac tctgtactgg aagcttacaa cgaaaccagt 159660 ctgaccgccc aataaggaat aaacgatgtc ttcaaatacc ccacatcgtg ataataagat 159720 gttacttcct ggtaacagcg agtttcagcg ggcgtttgat atcggtaata ctccggtaat 159780 caatgcagct aacggcggtc agtacggatt tgctccgaac aacttccgtt atgtccagga 159840 acaaccttat gtatcgcaac gcccttactg tgtgatgctc tctactccat ctgcattctc 159900 cgcaatgcct ggcggtaaag aactccacgg tttgctgcgt gcttacatgg aaactcgaag 159960 ccgtaactgg tcaggtctga ctgttcgtac ttctgttgac tatcatgata tcacttgggc 160020 gggtggtgct acactctcct tcccagttgg ttctagtcgt caatttggta ctatcagtca 160080 taacgcactt gatccagaag gtgaaccgtt ctccaaactg tttgatgctt ggattagtta 160140 cctgttgaat gacccagtta ttcatcatcc gaagatcatc actttgaact atggtggtga 160200 actcctgctt gatgagatct ctgcaagttc tgtttacttc gaacctactc gtaactggca 160260 agatgtccgt catgctgcga tcgtccttgc gcaaatgcct aaggaaggtg ctcagtatga 160320 attcagttat gatgtagatt ctccgtcagg taaagtccgt gaaatcaata ctgagttcac 160380 tggcctgatc gagtttgaca cctacgctgc taaagagatt gctcgtagtg taatgaagcg 160440 tatgccgatg tacaacccaa gtggtcgtgc ggcacctgct ggcttcaagc aacctactgc 160500 tactctgcaa gcactgcgtg atggtggtct taccgagatg atggctgaag ataaacgcac 160560 tatttctaag ccgaactaca tgccgtaaac aaaaaaaaat aatagacata acctctggaa 160620 cccaattggg ttccagaggt ttattatgtt gttctgtcat gaaagcaaca ctacacgtca 160680 atccttaact aataccagat tgataatgtt atttttgaac tcattaaaag cgactagttc 160740 cttctcattg agttctaaag aggataactc ctcctcatta gcgacagctc taatcagttt 160800 gtgtaatgga ttatctttag gatttaatga acttgcgtac tctttaaact cagctattgt 160860 ggtattaaac ggaatacaca acgaataact atgtctaagt acatgtaagt tcttaatcct 160920 tctgatgtcc atattgtaac gaatttctaa agaccactct tcacctttgt tttctcctac 160980 acaggcgtag atattgttct taaagaaact atgccaagag aaggctctct tttcagagaa 161040 ctcttgattc gctatatatc tccacgccca gtaactgact attaatgagg tgaagatagt 161100 tatcacaata ctgaccgcta tcatgccgag tgagtaccac atgacaatta ctcccggagt 161160 gaatcgaaga cctcttttac aagcaagtca aattcagctt ctctttcctt acagagataa 161220 ctactgaatt ctttccactc tttgtcaaaa taggttaagc ccaagtcagg gtagcttttc 161280 cagtggtaac catcaggacc gaacttttct actaagtgtc cctttacttc ttcgaaaaac 161340 tccagtgttg atagtcgatc aaggtctccg cgatgttcac ggaattgaat acatctttga 161400 atgtataact tgatctttgg acgaccggaa tcagcaatac taactatttc gctaactttg 161460 ttagtcggct tgttcttatt ggaactacga tgttctaaaa ccgcgttagc tacaatcatt 161520 acttcttcgg aagtataatc gaaagcacag aaccgattca gatactcgta ggttaacccg 161580 tacccaataa cgtgatgttg agagcgttca tagcaacaac ccaaatcgtg aaacagtgct 161640 cctaagatca ctagttcctt ttcacgacca ctcatcttct cttgttcaca aatgtctact 161700 gcaagtttac atacagcaaa tacatgctca agattatgag ctttatcgtt gcgtgaaata 161760 ctctcaacac agaatttcaa cagatcttga ttaagaggaa tgctgcgaaa caagaacttg 161820 aacttaaggt agtattcatt aactttttca agcaaactga tttcgtggtt catttctata 161880 ctcctttaat aaataatagg ttaggttaca caataataat atatgtttga aaatatttgg 161940 aaataaataa acaatgtata aaagtagagt aggagcattt gctcctactc tttttgaatt 162000 aagcttgctt attataaaca ggtttttgtt tcaactctac atctacacaa tcattaagat 162060 taagaagctt taccaaatag gtaaattcag ctacagtgta cattggggag taagctgaac 162120 caaatgttgc atagtcatcg tcaactacag gttcttctac taccaaggag atcagatcat 162180 caccaggaag agtcatgatg tattcaatag cttccttaag attgcgatca ccgatgttag 162240 tagagaaagg tttggcacga ttctcgtctg cttcaaatac ggtagtagtg cctttagcat 162300 aatgacgaat agaaaactcc gatacagcat actcatcagc gtaatcacga tactccaaat 162360 cgtgtttaac caatagtgtc tgagttctcg cattacacat caaagtaatc ggatgatgaa 162420 taccgtcatc agtttcacga tcatagaaac gaatagctgt gatgttagga agaatacgac 162480 catattctac acccagttta cctttaggga taacagtaac tggttcaccc agatcacctt 162540 caaaacgact actcaactct tccatttgag cttgagtaag accaataggt ttcatttcat 162600 ccttagcgat gttcatttct atgtaataca taacggcaaa caaaaacatc atcccaaaaa 162660 tgatagcaac aggtttggtg tatttattat tggtcatttt ctatattcct ttatctagac 162720 ttaaaagtaa tgaaagttga acaaggtaac ctagaacatt ctaggttacc tctagttata 162780 gtattaacgc atacgcggca tttggtactg aactgtaggt gagtggcctt taaccaaggc 162840 atgatcacaa gcaccatcaa actcttcacc ctttacaact ccgtttacat tcttaacgaa 162900 gtcttctact ggcatagacc aagagtaagc agtcggtgta ccttgctcat agttgtcagt 162960 ggagtagaac gcaaatacga tagtgccgcc tttgagttta ctgacacgtt ccatagcttg 163020 ggtgaaagta acattacgac gatcagacag gatcaggttg ttatcccaat cgtcgtaaac 163080 cagtcgtgct ttgttacctt gacctttcgg atagtactga atagcaaacc cagttgagta 163140 atcagttgcc tggttattga tatcagtaaa atcatagaac accgagtaat cgctgttacc 163200 tttagcacaa acaaaataaa cagtttgaga ttgaatgcct ttcttcagct caatactcaa 163260 aaccggatta ccttgattgt tcacataagt gttggtgatc actgcttcag cagcacgaat 163320 gttgtagtta atcggttcag gatcagcaga cattgctact acatcagaac caactacagc 163380 cataaacaga gcaaacaaca tagattggat tttcataata atttcctttt atcacgtgaa 163440 agtgtttact cctattctcc gtgtaggaga ataggagctt ggtacaaact accgcaaggt 163500 taatacagta aggtaatgta gaactgaaat atcttggatc ttaaaattta cgatcttcag 163560 ctttaccaca cacctgtttc aaatcagcta caaattcacc aacgaattca taaccagtaa 163620 acagttcatt accgacagga ataggtgtca tgcttttatc accagtttcc cgtgactcac 163680 gataacgagc acgatcacca ttttcaaaac gactgattac aaaaccttga tcagtgtttt 163740 caatttgctc cagtaccata tcagatgtca tggaactcag accatagata ctaacatacg 163800 ggaaggtatc ttttccactg gtactcaaag tctcgataat aaacatttct acctctttac 163860 cattaattac gtatttaacg gtaaagggtt cacctttctt ttcacatcca atggtgagaa 163920 caccgtcttt attaccagtg ttactgattt gataagtgac tagcttatca tcctgtttct 163980 ctttccaacc aattacttta acctcggtag ctacactgaa gaaacttacc atagagatca 164040 tagcagcaac aaaatacttt ttcataacaa atgttccttt tgaagttaaa caattcctac 164100 tcaatacact aaaatgatat tggtttgaaa aagtttgcat cttaaaattt tattttatct 164160 ttgtagtccc ttaatgtatc tccatgttta gcgagagtct tttcaacttc ccctacacag 164220 aaaatgatga aattattaaa cctatttaga aaacgaagtg aattaccttt accacctaaa 164280 tagatcctac ttttatggtc gcatgatgca atttcaaatg ttctcccatg tgtggtagaa 164340 gacgtaatag caatagtaga agtatatatc gaggaagggc cttcagagtc gtttagaaag 164400 cgtttgatgt taaagtaata cgtttccttg tctttagact gaagtctctc tatagcgtct 164460 tctacgctgt tttggatgac tttaagtttc ttaataaagt cttcataaga atctatcacg 164520 ggaataaagt cattactgtg aattataatt agttcaccac cgaagaagaa agttacttta 164580 gtgctatcgt gaaagttaac aaactcttct gattcgtcat tcttgttagc acgtaaccaa 164640 ctttgctcag ttagatgatg ttgaaacaca gcagcactaa tacgatcatt cccctccaac 164700 caaactcttt ttactacttt ggcacaaact ttcgtactca tctatattta gtccttctga 164760 tttaagaaat aacactaaat ccttaacaga gtttttatta atcgcaattg tccataactc 164820 tgctgtacaa atttcataag tatctggaat gtagattttt cttatcttga aactctcttt 164880 ataagaatct atatcaatag aacctttttc aaagtcacaa gcaaaccttc gaagctcttt 164940 aaggattttc aatcgtgctg ccatgtagtc attactaaat ttgatataga ctaacttatt 165000 aactaagtgt ctgtaatttg caaacatctg tactggatct tgtttcatac ttatcctaaa 165060 ataaaagtaa ggtagagaag ttactctcga cctaagccga gagtaaccat aacgttcaat 165120 taatcaaaca gtttcttaac acgttcctgg ttaacacctt ggaactcatc ataccaagta 165180 gagagttctt cattgaacag gtgatctacg cacagatcag tgatgccata catggtctct 165240 tcaccaacag tagttttcaa cattgcagtt gctgtgatgt cgattccagg aaccagactc 165300 agttcagcat cccaatcagt gaccttggta tcaggatact gagcaattgc gatttcactc 165360 agagctgctt cagctgctac tgatacctga ttaacgaaat cgttatgaag agtcaacgat 165420 tcagcagtga tacctttagg aagagtaggt gtagcaaaag ctacgtgatg agtatctttg 165480 tgaatggttg cattcttaac cagttcagcg atagaagaat ccatggattt agcgaatgcg 165540 tttgctttag acattgtttt gatttccttt gattgtttta ttggagagat taaaataact 165600 ttcttatcta tacactctag taatataggt ctgaaaaatt atagaactac taattttaac 165660 tgatgaattc ggtctctaca atacgcttaa cactaacggg taatgctcgt aacaaatact 165720 gatgtgcaac ttgatctaga tcgtcatcta ccagcttagt aatagataaa atggttaaat 165780 cttcttcaac cattttccac atatcaagta tggtaataat agacatgtgt aacatgtgcg 165840 gggtaggttg cttagaactt actgaatctg tactaacgtc tatacaacca gctgtaaact 165900 taaaggtgat aaagttacaa ccccgcaatt tcatctcaat aatgtattca actttatcac 165960 cgctaccaat tagatcgaag tcaccgaact taactaaatc tgtagttaag tcaacccgca 166020 tggtcaacaa aacaaaacag agttgtgcta ccatttgcgc agagaacata ttttcgtgtt 166080 taactgattc agctttttcc aaaagttctg tgtcgtttct gtacaaagca agaataatct 166140 ttttagcctc gtcggctaga acaacatatg tcttgcgttt actagtttga atatagaaca 166200 tttgacacca tttaaggtat gctaatttaa aatgatcctt ttctgaaaca ggtactgtaa 166260 aacttccatt gttattcacg gtaataaact caggtacaga tactgatccg tccttaacag 166320 cttccagcat cattccaggt tcaaatatct ttgatgttgt tgtagtattc attattctat 166380 ttccttatta aagtgtttgg ttaagccttt attagtttct tttaacttaa caatcaaatc 166440 tttaagtgtt tcaggataac ctgcaaataa cactttgttt aaagacttag tattatcaaa 166500 gttgattact actattggaa tacgtttacc atctttacct ttatgttcac ctggagaaga 166560 cgttacataa tgactaggat tagatttact caatttaacc atttgataaa cttgactgtt 166620 cttttgtatt agttcaagtc cttcaattaa atctgacaaa tgaccttgta cttctccatt 166680 tttattagtt acaaatccag tgtattgacc accttctatg ttgatattaa atcccccagc 166740 attaggaagt tcataccaac taaatacact aggagtttca ctatttgggt aatcaataaa 166800 ataacttttg ttatttactt tatcagcaga tggatgaact gggaatttaa tctttggttt 166860 actacctggt ttactctctt taccccattt aagaattaaa ctcaatgtct taattagaaa 166920 gtcataactt tcctttagtc taagttcatt ctcttctact aactcaccag agacataatc 166980 cactaaacaa atagagattg tttcacccct agtgataaac atcctgccag actctccacg 167040 aacgattgta agagacttta caggaatgct agtacgttca cccatctttc ccttagaaag 167100 ctttctaaca gcttttaaga gtgtttcaga tacttcaatg gaatgatgag taaaccactt 167160 atccattttg aatattgtaa ttcgtggttc attatcacca gacattttat tacaatataa 167220 acgtcctact aaatctggac tatgacctag aaagaaatct tgataacttc gtttcaccta 167280 agactccctt aaacaaataa gaaatgagag aacgactgtt tcgtctccca gcgtaatcgc 167340 ttcaccataa ttatatcggt ttgaaaaatt atagaactat aaaaataaca gaagaaggaa 167400 cgacccctct tctgttaata aaatcattta gttcaaagta attacagttt caacttcttc 167460 agagttcaga taactaacca acttgtcttc caaacctacc aaagaaactt ctctggtttc 167520 atcatattga agtttaatgc cttggaaagt gctctctagg tacttggcaa gaatagtaga 167580 gttcttttcc ttactaaact caaacattac agtaggaacg ccgtacaagt tagtcatcat 167640 caaatcaaac aaatgacgat gatctttaat atcattacta gcgatctgta gaataatgga 167700 atctactcgc cagttaccta ctttgatatc ttcttgagta atagggaaca gggtcaaccc 167760 aataatagag tttacatatt tcatcagatc acgagcatac agctgaacca actgagcttt 167820 agaacgcgtt aaagtttccc gtacaataat agaacttcca tcttcagaaa gaagtttctc 167880 ccaaacagga atcatttctt taaaagtatt ctcaacagta aaggcttgtt ctacaaattc 167940 aatagcgtga gagtaacgac gaacaacttc cagattaaaa tgcattagaa aactcctgat 168000 ggatatatta aatgaaatag ctctacgata aatgtcaaac agagtaaaaa cataaataaa 168060 cctacttctc caattaagga gaagtaggtc atattagaat acgtcgctaa aggaaacacc 168120 aacacgagtt gtgtcaccag acttgtaact gcgcttaaca gcttctacca tatctttcat 168180 catgttaagt gattccatac cacctacacg ttggagttca aagtcgctat tagcggcaag 168240 agcaagttga ttgtcaatct gttcaataac atcagaggct ttaaacttaa tgacgttatc 168300 catccccaga ttaaaatcag aaagcatgga ctcacaacca gctgtcatgt gcttattagc 168360 atgtaagaac ccaggttcct ttacccagtc ataccctgtc cagtattcca cttctttacg 168420 agtttcacca ggcttaaatg gagaaatctg agtacgaata cttacggcag tgttatgttc 168480 aggagtttcc aaagattctc taaactcttc tgcccgtttc ccaaatggtt tacaatcaat 168540 ttcattccaa ataggagctg aaagattatt agggttttct ggacggaaga ttacctttgt 168600 gattaaccca caaacattat cgtcgtcata actacgaaga cgattaatcc actcgagaac 168660 agatgtcatt gctttacgat aacgaacacc attctcttct acatagaaga aaggttgcgg 168720 atgttcgcgt tccatcaagc aataacccat gctaacacga cggttaaggt cgctattagc 168780 ttccatctgt tcacgaatat atttgttagc aggataaaca ataccagcgt ggttaggaat 168840 attgaaccca ccagcattca aacggtaaat gccatctgag tttggtttga gaataccttt 168900 tttaccacta ttagctagaa cgatattccc aaagctaatt tcactcattg taactctcca 168960 tactcttcag gaagaccacg gatcacctct tccaacgttg tcatctgagt atctgggtta 169020 agaataccac tgacaatgtt atcagacata taacctgaag acaatctact aaatgtgcta 169080 ttaagtagtt gacccgggtt gttaataccg atgatacgag gtttcacgga gagatcttta 169140 aactgcgggg aataacgaaa cggaatatcc aagttgacag gatctcgcat tgttaacgaa 169200 aacaacactc tgagtacttg agcagaacta cctacttttt tacctgcaaa ataagaactt 169260 tcatcaaaga tattcaatag cacgctttca tccatatacc atggataacg agcgtatttg 169320 atgaattcca aataaaagta atagatcagg ttagcgtcct gcggaacaaa gatgttttca 169380 ataacaacat cacccggttc aaaatgcatg acatagtaac gttcaccctt aataacttcc 169440 tcagaagtat caccgggttt catgctaaac cgtgtcagag aaccaaagca agaatagtag 169500 tcatcgacca ccaccccaac tgccataatt gtatttaccg aatcaccaac ttcagccaaa 169560 ccagattgtt cgaagcgctt aggaatgtaa cacgtcatct tcttaagagc aacgactgta 169620 ttatcaggca tgactttaag ggcggaatta atccgccctg tgtctttctt cagcttatcg 169680 aattcgatca cttggtatag atccgtttga taatcgcttt gataatcgca ccagtaagaa 169740 ctttacgttg atgttctact ggacctggtt cgcctttagc attctccaac aggatttcgg 169800 ctgcgatctc tgaaccaaat accagacaga gttctttagc cataccagtt tgaagcaggg 169860 aacgtttacc tttacagatg tcctcgatca tcatcggatt accgaagaaa tcgttaaggt 169920 tcattacttc ctgaagtttg ctaagaatac gaacaccttt aggaacactt tcatccatag 169980 tgttgacaat accttcaaag ttctcgtgca tctccatacg cttaatcgca gtaatgaaag 170040 attccttaga gactttctga aggttatcat aaagacgagt agtgagatcc tgctggtatt 170100 ctctcagtgc atcttcaatt acattagcgt cggtcatgat atctttaaca cgatacccac 170160 gttctttagc atacaaataa ccaagaacgt attcagacag actgtaactg gaagcttcac 170220 taaagagacc caagactttg ttattgtaac cgacagtaac attaccagta agaagtttag 170280 tgccgttgag taaaccccag ttagcttctg tgtacttaac atcaccatca acgattacaa 170340 taccgctagc ggcctgaccc aaccagatgt tacggaaacg taccaatgaa ccagacagga 170400 tatcacgagt catagcaagg gaaccgcgat agtcaaccag actaacacca gttacacctt 170460 ccatcggatc ttccatagca cacagtttat ttaccaacaa gttggcaata acaatagcac 170520 ggaatttacc aatatggtaa ctatcttgat gcatgacatc aacaacacca ttctgaatac 170580 cggcgctact aaagaagtca tgccaagctt tgttaacaaa gatccggcga tacacttcca 170640 gtacttcatc aggactttca aagaaagtat aaagaacacc agaatcgaca cggatcagat 170700 cgatcagttc ttcaccagtt ttgtcatcag cccaattacc tttaagtagt tcattaagtg 170760 ctactttaga agtctccttc aaggtattag gaagttcagt tggacagaac ggagagttaa 170820 ggaaatccgg ttccatgtta accattttga cattcagata gtcaaaggag agatcgacga 170880 cattctgaac atttagatta cgagcaattt cgttatccgc ttctttcaaa ataggtttaa 170940 cgtatttact gattacgtac agagaactac gaatgatctc agcaagctta gtggagacca 171000 tatccattac ttcggtatgt tcgggaacca acttggtgta atcaggaagt tcagtcgcaa 171060 tgttgtccgg agtaaatcca cccagggaag cagtagtgtc attcagaccc ttgatgatat 171120 cagaactacc ttctgacaat acagtgcctt tctggtctgc ttccattgca ataggagtta 171180 caactagaat agtgctttgg ggaatcatta ttcttctccc actacagcag atttaatttg 171240 acgggagatt acttcttgtt cctcaacttc gctcaaggga gcttggaact cgtaacctac 171300 tttcttcaag gtctgtgaaa cgacctcgta catattagac aacgtgatga tgttgtcgac 171360 agtgttttcc atgagaatac cttatttagc aagacgaagt tttggatcca taccttccca 171420 atagaaagta gtaatcgccg aagcaatatc accaacggtg tagaaacctt tcttctcgga 171480 atcaaaccca gagttttgct cgtagagttt agttcccttg gtaccaacta ccaagttagg 171540 atctttaccg acatgagcag gatagaaaat agagaggtaa taatcttcaa gacagttaca 171600 cttcttgata tagctgtact tttcaaagta tttgaaaacc cagtcaagtt gttcaaatac 171660 tgacatgact tttaactgat catcagttac accaagatct ttcatagaac catttggcat 171720 gaattggatt aatccacgag ctttgctatg tttattcaat gcagcgggat caaaagtacg 171780 accagtttct aaagcaaaac aactaaacag atagcttaca tgatctaatg gtttacccca 171840 cttcaccatc cagtcttcaa ctttcttaat tacttcagga gttaagttct tgtgactagt 171900 ccaggcataa ctgtaatgag gaaggttatt atcctgagcg tagatattac aaagcttctc 171960 taactcacct ttgctagcag ctccccactt tccatctacc ttaaactcaa caggtacctt 172020 accagctcgt acaaggtatt cttgaaccca cttaaataca tcactagcca agtaagtagg 172080 aacagctaca atcgggttgt agttcggatt aacgtgttta acaacactat gcattgcgtt 172140 tacacaacca gtcccaaaga gggcgtcaat ccgccctcca tagagaccaa cttcccgaaa 172200 aagtgactgg atagttttca acccaaacac ttctttgtta gtgttagtca ttttattcat 172260 atctcccata tttcttcatc atacgactag tgtaaacatg gttcaattca ttagctacca 172320 gtttatcacg aagactcaac accatccggt taagcaaaga cttcaaagag aacttaacat 172380 cgacttcccg accatcgaca gtatagatag gatctggata aatgaaacct actgtacctt 172440 tcatctggtt acctgctacg aacttatcag cagtggtggt agtgagttta ctctcaatgg 172500 taatagtaac agaagcagta ttaggataaa ccttagattt acctactgag gtattaccac 172560 ctacgttacc attatcagca gcaagttctc tgaacttagc tttcttagca cgtagcttat 172620 cttgctcttg gataaacgct ttcaaagact cttcggctgt atcaagatca ccattataaa 172680 taacgtcaat cttggtaatc acaccagctt gtttagcctt gatttgttta atgccaagac 172740 gatccaaacc agcaatggaa ttaacacctt cctcctcgaa catagcagaa gaaggatcca 172800 ttacatcagc cagcacttga tcgtactcaa ccttgtcgcc taccttaaca tacagtttaa 172860 tcgcttgttc ataaccgata ttaaacacat tgtttttcaa gtaaggagtg gtattcaaat 172920 ccgcatactt ctgcgtaata ccaatggaat cttcaaatgt gaattgatct tctaccaatg 172980 caatacgtgc cattgtccca agcttaataa caatccgttt tggattagtt aaatcccgag 173040 tgtagaaaca atcatcccaa gcaagtacat cacctttctc aactttatca ccaactttca 173100 tatcggtgat tttaagatgt ttgtgatact caccagcacc tttacctact tcatagccaa 173160 gtgggaattt ctcttcacta ccattatcat acttaacagt catcccgtca gcagtgatag 173220 cggtaatggt acccacttct ttagcataag aacaatagag ttctgagtta cgataagcta 173280 ctacactatc agaaggagtt ctaatagggt tagcaacata actatcagta gccatccatt 173340 gacttagctg aacgcctgag aacaacgcct tatgtccggt cttatcctaa gacccggtgt 173400 gctagacacc cgccttatat cactataagg agcagactat atttcaacca actgtctagt 173460 tgcttcttca gcaacacagt aaggtaaccc tgtttggtag gaacattcct tgttcctgct 173520 acggggagtt tcacccctag tcgttgaacg ctcgtcctat ctattcatca cgaatatact 173580 tagacgctcc gctgctgact gtctctccgc tctacttttc aaacctttcc atataacctt 173640 tcggtttccg tttcggtaag agcatctttg agtacttccc agcaattaag ggttaatgca 173700 aacactcatt tctaagtgta agggcagtaa cgtcgaagtc atcgacgctg tgtttacctt 173760 ttactgtcat cgcgcgttgt accataaagt aggttagcgg ttactgatcc acgacctgca 173820 ttagtggttt cttgggttac atccacgtta ccagcgtagt caacaatctt ggcatcagaa 173880 gttagataag agataaatcc tactttaccc gagtccttac cagcttcgga gataatccct 173940 gcgtaacttg gcaattgacc acgagtacgg cgtaccattg cttgatcact tcgaccaaag 174000 gtgccaccaa aggtaacttc ttcctgttgc ttgatctggt gagctggatt gacttcttca 174060 actggctgca tactgctatc agtcaggata ttcatcatga tagcttctgg gttcaagtca 174120 aaggtcttct taccagtatt aggtttgttc ctaaactgtc tagtagactt aaccagttct 174180 cgatatacgt gaccagggaa tctctcgaat ccaaccaaac gctgttcagc aatctctact 174240 tcgtgttctg cttcgttatt aaggagcatc tctacagcac ggataatcag cttatccata 174300 atgagaggat aaccacgacg ttccaattca cgagcagtga taggatcaat gaacatatcg 174360 taaatcaaat ccatctcttt aaagtgagat ggtttaacac gactatcatt aatcaaactg 174420 aaccatacgt taggatcgtc caattgagct tttgagaagt tagctaaacc atttagcttt 174480 ctcagtcctg agaagatcag agtactcaat ccatctcgac gatcaagaat caaacgctca 174540 tcagcaaact gaacaatata ctcgttagca ttaagcatag gacgagtacc tggctcaaca 174600 acacgatgag taggtttgag acgtttcact agttcactaa acccaatcca gtaagcaaga 174660 actactacta cagggaactt ataaccatta atgttcgcag ttgcagtagg aactggggct 174720 ttagccatag gtaaacgaag aatctcttcg atataacctt tctccacacc atcgatcatt 174780 accaaaccag tattatcgat tagtacggga actccgtgct catcaccaat gacccaacta 174840 tcacctttac aatacttctt ccatttagga tgtttcacca aaatagattc agtatcaaag 174900 ttaaattcca aaccaccaac agtaatctct ttaaagcgag aagccagtac tgaataatac 174960 caacacactt ctttaagttc agatttaaat gaacctaatt taactgtgat agatttgtct 175020 tcataactct tctgaatgat attagtctta agccaatgat tgtaatcgtc tactttataa 175080 gcagaacgtt caatcatcag tttcttatcg taataagaac taatggcaac cttaactgga 175140 ttgatctttc taaccggaag atccatgcgt actaactgag catatgactt aaccccgtta 175200 atagtaaaac taccgtcaga agccacctta ggtaaacgga actgtctggt ggactggtta 175260 ccattatcaa caggttggag tttcatcttg taaacatcgt acttggaatc agcggtgata 175320 atggtttcac gattcagatc cagtaaagca gtaccgccgt tctgaacagc tagaatagac 175380 cccatgatat ctcgttcaag gaactgttct acatatccct tagtaagttc catgcttcta 175440 gaacgcaata cagactcatc tgtaacagct tctgacttag gtgcaaacgt tttaggtttc 175500 atcaccaagt cttcaggttt gatatcaaca atctctgaaa gtaaatgacc accaaactca 175560 atgtctttat aagagacact tgcgttagtg taatactctt tctctttggt tgttaattga 175620 cctcttgctg ctttacgttc cagaatacga ttgatcgtac taactggcga ataagcttct 175680 tcagagttaa caatagtagc ttgttcgatg ctagcgcgtt caaagacact atcatctatg 175740 tcggcacccc attcttcttc cggggatttc tcagtggttt cagtaggaac tgagttgttc 175800 tcggattcgg aactcccagg aagtgttcct tcaggagttt tctctccttt tgttcctgag 175860 gtatcagaca ccgcaggagt agttccctta ctgctggcat aaagatcagc caagccacca 175920 ggagtagtat taggtaccag aggggacttt tcttcagact ctcgtccaga tcctctccct 175980 cctttttccg atcgatctcc caccacttct tctttggtgg tttcttctgg ttgctcataa 176040 ctctcttcca caacttcttc agaaagcgga ctcaccagag aaatcaaagc aaggtagaag 176100 cgcttgaagt agttaaactt aataggacgg ggagatgtgt cttctggttt atcatcgtac 176160 ccaatcaaat tgattagtgt ttgaagatta gcaatccaac acactccgtt ataactaaag 176220 atcaattcta gttgacttct agctcgatca ttcaatcgat taaacaaact gtattgttta 176280 ttctcaaaac caatcagaat accaaataga tctaatagcc agaaagattc ctcagcttgg 176340 aactctttta aagcttcctt ctcatacttc tcaataacac cttcattatt aaagaaacgt 176400 ttatactttt caaatttaag ctctaacgtt ttataagagg ggaacgagcg aggaagttta 176460 aactctacaa actgatgaat atcgtattga ctaaactcat tcacagattc cattaatgta 176520 tagagttcat tataggaacg ttggaatgga gtgaatacag tttgtctgcg atactgaaca 176580 ggaatcttac caatagctaa gttgttaact aacaattcac cttctttgtg aattacagtt 176640 tggtattgac gagcgcgagt ataaaggtaa tgaccgcctt catattgctt gatcaactta 176700 gtcaactgaa taggaacaat cttggtagtt cccagaggtg tttcgtaatt aacattaaaa 176760 aagatgttaa tacgtttgtc gtagttgcta ataaaagcag cggtgttact aggccccagc 176820 tcaccaggaa tatttccctg gtaatgaatg agactgttac gaggtaacat gatatccccg 176880 actacttgat atcgtgggtt cactacatca ttagcacgct ctcgcgtacc gtgtagttta 176940 acgaactgag agtataacaa tccctctagt ccgctaagtt cgtcaaagtt tactggatgt 177000 tcttgcatta cgataatcca ttggtcaatg aacgtaaaag gaatgcgtgt ggttcctgta 177060 cagggtcata tagaaagtca cctgctccag aaatatagaa tatacgttta ccaaacaaag 177120 tttcaatttc ttctactgaa tctttagctt gaatactgtt ggcggataat tggtccaatt 177180 gttaatgtga agctttttat cttcactccc agatcactcc gggtatcggc gtacgttttc 177240 atcccagtag gatggtgcgg cctcttggat agattatatt ctctttaatg aaagaggttc 177300 actatctacg ctctgcccct gactcactat ttacagtaag ccttcggttc aagttatctc 177360 taaatggaga ggttccttgc ttcattccgc acttattcga ttagtattac tactaaaagc 177420 ggcaagctga aataccgtca aaatcaccac cagcagcagc taagcgtatg ttactaatac 177480 tcatcccatc aaagaaactg ggatttttag tccacactgg aaagaagtga aaactatcca 177540 atttactacc atcaatatcg atcaatgttc ttgattctga tgtggctgta gttggaagaa 177600 caaacactcg tgtaggtaca atagaaccta tcccagtaat tgggtaacga gtaatttgta 177660 acatcttctt ttcaatcgct tttacggtct ggatataaaa gaattgcata taggtaacag 177720 gatggagatg tttcttatcc attccttcac ctaggtcatt tacatcgtga actaagcaaa 177780 cgtttttacc atcatcataa agtagaccta ggtaatgacc tgctacctta ataggacggt 177840 tacgaacgtt aggatcacta aatccattaa agagtttccc aattccatca gcagaagtaa 177900 acttatccac tgtgtaagga tccacatcta cgtaagcact ttctaaactc ttaggttcca 177960 ccagacgtgc tttatccaat ccaggagtaa atacttctga taagaaaccg ttaaggagtt 178020 catgagtagc tactaggtta taacctagta gtgcttggta catcccaatg aacgtagagt 178080 taggatcacc agtggcatta tcgtccatgt tctctacaga gactttacga gagacgatta 178140 cgttacgagt tgcagagtga atagaacgtc gactcattcg acgctgcatg aaccctcgtt 178200 taccttcctg taactcaaag agatgttggt caatattatt taaagactct tgcattcccc 178260 agtgaatgtt atcataaacc ggatcaagtg gatcagggtt cttagtggtt agtgatttag 178320 ttctgaaaat caatttacga taaagatcgt taatctcatt ttcagtaact aatccagtag 178380 gtccgatttc aatgtctcgg atgcccgctg gaataactgg aatgtgatta ttcaaagctc 178440 gatcacggaa attattaacc agcgtgatct tctgagttcg tttaaaagac tgatttggtt 178500 ttggatctaa ttcaccaaaa tgagtcataa aaaacgcaaa tcctgtatca ccttccagga 178560 cgttagattt tatgaaatca cgttctgtct catcccatac agcatatgtc ttacccttta 178620 ctatatctaa gtaaagtgat tttaactgta ctaatgcttt aaaatacgtg ggattgaaaa 178680 taggtaataa ggtattaatg taagattcag ttttatctcg ttcatcagta cctactcgac 178740 caaagatcct ggtcgagtag agtccgtctt cgtgcaagtt agtggtttga ccttcaaacg 178800 aatcagctac tgtcacgggt gacatgagtt ctattggaaa cgttttagga tcaagcagcg 178860 taaagttagt aggttgtcta ctcatcgcta tttcctaagt gagggaatgt atggcaagtg 178920 atacttatga tctagactgg gatgatgatc cttttggtgg agatatcgac tttgatatgg 178980 atttcgatat ggatccatat gcaaagaaag gttttgtcgg gggcatggcc tctggattcc 179040 tttctgggat tgtcgatgaa acagttggaa gtggcgaagc aagaatgcgt acacttcgaa 179100 ctattctccc taaatcattc tccacagcgt tagatcgggt cagctgggct ggtcgtagat 179160 ttgacgaatt aaaaacagaa tttaaagaag aaaatgcttc ttctgttaaa tcgttacaaa 179220 gcattgcggg tcatctgtca aagaaaatgg gcgaaagaat gcccagttca attacaaatg 179280 agctcgagaa tttctcccag aaagactttt ctagttggga gaaattaggt agttatgaag 179340 ctggcggatt gtccattgaa gagacaagtg agtatgatgt taatgcagct ctagatcgtt 179400 ccttagaagc tcaagaagga atgttctcgg cattaggcga aacactcaat accatgtccg 179460 ctcatgttgg cggaatgatt actgcgagta tctcatctgg taatagacaa cttgttaata 179520 tcgaatctgg aatgcgtgat ttggttaact accaacgtaa cgttcaactt cgaatggatc 179580 aggctaaact ttctttatta gccaagactt acgtttccaa cgttaagtac tataagttca 179640 tggagaaagg aattcatact gaaattgctg aattgaagaa gattcaaaaa gccagtatga 179700 tgagtgatta ccaaaagact tctacattta ctgcatctaa agagtttatg agaaataagc 179760 tttttaacac agtaggtaaa cgagtaggtg gtcttactgg tttaattaaa gacaagtttg 179820 gtaaatcggc tagacaggaa ggttatcagg gcggtaactt tgctttagaa caaattgctg 179880 acatgttgga tatgtcagat ggaatgccga tgtccaaagg gatgattggt gatctaattg 179940 gcaaacaact aggtagtatg tttgtttcca atatccctta cttctttgaa cgtggtaaag 180000 gtaaagattg gattaataag ttagcagcta aaaatcccaa agaagctaaa cagttccaag 180060 agatgtttgg taaactaact aactttggta ataaagcttc ttacgcttct acatctggtg 180120 ttgggttaat aaactacctt gctgaagatt acgaagctat ggatgagatg cagtatcttg 180180 attatcaaga ttacttagat caacttcctc caggtaagaa accaattcca aaggctattt 180240 gggttgctaa gaatgcggct accaacaaag ctaaagcctc tgttaacagt ttcatgtctg 180300 agattactaa atctcgtggg acccaatata cacttaataa gcgcaatgta aaagatctca 180360 ataatccagg tatctggaaa gagaccaata acattactct taatgaagtt atcccaggtt 180420 tacttagtaa gatcttaact agtactgaag gtattcgtac tggtgaaaag aatatcgaaa 180480 gtgtaagtta taactatatg cgtggtcagt tccaaactga ttccgaaaaa cgtatttctg 180540 ttaaagctga tttaatgcct tacggtgact ttagtcgtta cgctcaagct gctttggaaa 180600 tggttgatgg attggataca gaacgtactc ttagtcctgg tgctaggaaa gcacttgcgc 180660 agcagattgc taaagatgtc gatcaagaga aagggtttaa cccattttat tatcttggtg 180720 atattcctaa cgtatccggt tcccatcaaa aagaaataca tgctgtaatg aaacgtcact 180780 ttggtcttaa tgatcaagat gtttctgagt ttaagtccgc taagggtttt gataagctca 180840 agcgcatgac cgacatgcgt agtaacgagg gtaacgagcg tcttaacgta gcttccgcta 180900 ctgctgctaa catgaaggat ctattcccca atgtagcaga acgcatcgat atgcttcgtt 180960 ctaccggtaa tgagcaactg cttagagatc ttggtgttat ctacactgaa gctggggtag 181020 agaaagttaa catgaacatt ttccatgaaa gactgggaca gttcatggag aacccaaata 181080 acccacagct aaaggggatg tttgataata catctaagaa accagtaagt gatggtaaag 181140 gcgggtttat agtacctaag tcaccaactg gatcttcgtc aactaacaat acgtttaacg 181200 aactaaacag ttctataagc gatttgtcag cacagcttgg tagattgatt gataatactt 181260 ccaaagttga tacagaacgt tccagtggac ctcgggctta ctttgacact cataccggtg 181320 aagttgtttc aaacatcgat aagatagcta cttcaacatc taatatggat cttctcttta 181380 ctgaattact cagtattgta aaagatggga aactctttag taagcaagct aagtcgcaaa 181440 ctgaagaacg tcaagccgat cgttacaact ttgatgtagt aaatagactc aagaaaatcc 181500 ttccgactaa tattctcgga aaagggtttg aaatggttat gcaaaatcaa ccattgatcc 181560 ttggttctat tttaggtggt gtaagttcac actttatcca aaatcctatt cttgcagcgg 181620 cagctggtgt gggtggtatt gcactaggag ctttagttca acattggggt aaaacggatt 181680 atgcagaagg tgtaggtgac gaaccgtctg atgatgaaga catcctcgat gagaacggaa 181740 ataagatctt aacttccgct aaacttaaag ctggtgatta ttacgatgct gtaaaacgtc 181800 gtgtgataaa aacttggcgt gatatcaaag gtcctttgtt tgatgctgct aataaagtca 181860 ccattaccgt taaagagttg ggtggtaaga tctttggcgc tgacggacga gctgtagttc 181920 tatcaggaat taccaagatc aaagatgcgg cagtgggagc ttataacttc attgatccct 181980 taacacgcat taagtcggtt atggaaatgg gtaagaacct catttaccag caagacgtat 182040 atgtaaaggg tgagaagacc cctagactga gagctattaa gttcaaagaa ggtgagtact 182100 caattgagga cagtactggg tctattaaac ctatttgggg atggaatgaa attaatggtc 182160 ctgtctacaa cagtgaaggt aacgaagtta tctcccaagt agaatttgat caaggtctta 182220 ttactgcaac tggccagaaa gtaagagcag taggtagcgc tgcttcagga ttagctggaa 182280 cggccgcagg actcgctaga tcaggtttag ataacatcct aggtaagttc ggttacaatc 182340 gtccacaagg cgatacagaa gcttctggaa caggtaaacc aggacaaagt agtaaccgtg 182400 gtgtggaacg tcgtttagat cgcatttacg ccatgctctc ccagaagttc ggtattgata 182460 ttccagataa ctttgacggt gaaagtgatc ccattggttc acccatcgct aaggggctaa 182520 gactgaactc tttggaagat aagatcagac aagccaaagc agagaaacaa gaaaaggttc 182580 aggattctat catcgatatt gctgaaggga tgaaagaacc taaagaggga gagaaaaccg 182640 aaaagcaagg catcttcggt aaactcttta gcttgatggg aggtatgggc gattttgcca 182700 tgcgtcttat taagaatccc attggaacct taggtggttt gataatgggt tctctggtta 182760 actctggaaa acgcttagct tctattggta agatgttgtt ctcaggtgtg ttaggagcag 182820 cttctcctat cttcaaatta atgaagtggg ggttcactgc tctaactaaa gccaccatgg 182880 ctaaaacagc agcaagtggc ttaggggaca cattgggcgg tgctggtaga ggagggatga 182940 gaggtaagat cggtggagta cttagtaagt taggtggtcg aggtaagatg ctggctgctt 183000 tattaggtac tggcgctgta gtaggtggtg ggatgtacgc ggctgatgct tttggtggtg 183060 aagccgagcc cactgatgga gatgtgtacg aagatggtaa agacgacaat ggtccaaagt 183120 taactactat ggagaaagct gttgatacag cttctgattt cttcttacct acacttgctt 183180 tgaaaaccgc taaggaattc ttgctaccaa aagctgctag tgactttatc gagaacaagg 183240 gtgtattctg ggctcctgat ggaaccttct ttactgaccg tcgtgaagca caagcttaca 183300 ttgatggcac tggtggtgtt agtgctaaag aaattccaga ttcactacaa cgtcgtattc 183360 gttatgctca gtacggtatt aagagtattg acggtaattt ggctaaacgt gtttctaagc 183420 tggaacaagc gttaattccc catttggcca ttgctaataa cagagcaagc ttctctcaaa 183480 gcgctcctgt tgcacagatc ctacagcagt ttgctaaagg tggagatagc gtcccatttg 183540 atcaagttca cacttggttt aatgctcgtt tcaaacctgt gttcttgttg tatgctgtag 183600 cggtatctat cgggagacat ggtgacatca acgagtttga tcgtaaagag agttatgaag 183660 ttacgttact ctgtgaacgt gtaagaacct ctatgggtac tttggatcca ttcccttatg 183720 aagtacaagt tcagatagat ccaagggaag gtattcttaa tcgggtcatg actgagaact 183780 tggttagttc tttactgtca gaacttcgta agaaatatcc cacccctgaa gaagagttca 183840 aactagaaac agatgtagaa cgtcgtaacc gagtattaaa cgaaaagact ccagatggac 183900 ttgctggatg gtttagcaat agttacggtg atcgtgctaa caaactcgct caagaagaag 183960 ttgatcgtaa gttccaaaca ccacaagctg taagagagat tgatatctct gatttgcata 184020 aagatgctaa tacagctatc gatccattta ctatggtccg tttaggtgtt tatggtaaca 184080 tcgacaatat gccttggcga gttgatgctg tacttagact ggaacgttat tgtgaagatt 184140 taattaatac gcttggaaca gaagcggtct ttagtggtaa ccctactaga gtatttaatc 184200 tgtttaaagc gcaatttagg attgaaacag ctaacggtga gactaactgg catctgtggt 184260 tccagaatcg tttcttacct gtattgcaac aatacgttaa ggaaatgaaa cgtcttcgta 184320 atcaactacc taagcaagga tggagatcac tctctgatac taacaaagct aagttggcta 184380 gattcttgtc agaaactcga gttatctatc agcaagaaga agtgacagtg tgggatgtga 184440 aagcttctcc atttgaaaat tctaattctg gtagctggcc tgatagagtt gagaagtatc 184500 ttaagtcttt ggatgctaaa gccactaaag cgagactgaa agaacctgag ttagaagatg 184560 aacgttcact tacttacgat gagaaattaa gtggaagtaa ggtcaactat agtcaagttc 184620 aggctaatac caatgcactg tttgataaag tgtatggtaa gaaccgaaat gtctctgctg 184680 gtaatgttgg tatttacggt ggtggaactg gtaattcatt tactgctgat ggacgtaata 184740 acaatggtct tgggtttggt actaactaca acttacaagg cgggaatgta aaccttggtt 184800 ggtcagatac ctttaatccg gagttccaga agttagctgg cgatgacaaa gggatcaaga 184860 tggatcctgc tcagggtgaa cagctcttat taaaccactt gttaaaagca ggtgtaactg 184920 ataagaagat gttggcactt gcactggcga tggctaagaa ggaaacaggt aactattcag 184980 ctacagtaga gaataccaac tggtctgctc ctactttgaa gaagtacttt agaaatattc 185040 ctgatatggc tactgctgag aaagttgctg ctttgtcacc tgcggaacgc gccatgtatg 185100 tttatggcag agctcctaaa ggtccgacac ttggtaacac taaaccggaa gatggatggt 185160 tatatcgtgg tagaggactg ttccagttaa caggcaaggc taactacgag aaattcaaac 185220 aagagactgg gattgatgtt gtatctaatc cacgtatcgt gtctgaagat cctaatgtaa 185280 tggctgagtc cgctgtacga ttcttactta atagtaaagc gatgcgttct attgcccaga 185340 caggcgattt tgaaaccgct atgcgtggta tcaatggtgg taatcctgtt cctggttccg 185400 atgaacgtag acaatactat caagagtact tggatcgtct taaccgtgga gacatttctg 185460 tacccgatac tggtgaacaa ggcgctgttc aaattagtaa tgaacaagcc cagttacctt 185520 ctgttccgga tagtaatgtt ccacctgatc acattgacgg taacaaagct gttaatccag 185580 atgctaagga agacatcaac agtttgatga acgcagcaga tactgctaag gtttctaata 185640 aacctgtttc accaactagt gtcccgacgg catccccatc cagtaggcct aaagcaccta 185700 cacctccacc gagtattgct gctcctcaac aaccgagtaa tacagcaact aatacccctg 185760 ctgttaatcc ttctagtgta atgaagacac ctaccaaaga agttccggta gaactcaagt 185820 tacctgacgg acctctggct gttaacgatg aagccaacac cgctgcaatg gctaggttga 185880 tcacatccgt cgatactctg aatgaaggta tcaatcgtct cgctaaacaa caaagtgggg 185940 tgaggatgaa ttaataaaac tgagtaggag ggtcaaacct cctactccct tttcttttta 186000 gaggtaacaa gatgagcgtc aagcttcctt ataaagacga taacgtgata tctcgttcat 186060 ttcgtttaat gagtgatggt atacgtaatc cagaagaagt gcttatcaga tctgactacg 186120 atctttatac cagtttcttc tccacagcta ttggagataa tcgatacatt aatcctctac 186180 caggttacgg tttaaatacc gatccttatc ctaagccgat aatggaaaac cgtatgggga 186240 atatgggaag gtattataaa cgtattcatc atgataatgc acaaactgct acatttacgg 186300 cttgtgtacc agagtttaca gggctcttga cattcctttt gaacatgttc gattattctg 186360 cttctgtaat ggtaactaaa ggacgtgctc cttcttgggc tttctacata ggtcaagccg 186420 caggcgctat tgcgttctgg ccagcacaga tcctagccac tagttacaac ttctttgaat 186480 atctgatgaa tgagcctaag aacaagtggt attacggtaa accagcaatg gggatgtact 186540 ttacagctgc tcaaggtatc ttcaacgact taatggtaaa tgccggttac actcttactg 186600 tattacccaa gcaaggcaac accttggatg taagagcagg tgatcgagcc aaagctggta 186660 atagaggata cgaaactaac agttctgcta tgcgtaataa ctttgcatat atgaactccc 186720 tattcccaga tgctattaac gaagatggta caattgacat tactagatta agtctacgtg 186780 gtgttcgtaa gtatcgtcat ttcttagcta aagtaaaaga ccttgataag aataccggga 186840 ttagaacagt tgaagaaaaa gatcaagcta ttgaacagat tctagatcag cttattcgtg 186900 acggtaactt cgttaacgga agaggaacca gagctgaagg taagggtact aaggagtatt 186960 tggatgctga attacgtagt gtagcggctt ctagagggga agatgaaata gcttacccag 187020 aagtagcctc ggcttatacc gatccagaag cttactctaa aatcaaaccc tctaatccag 187080 ctctttctgt ttctagtgga gtatctgaaa atccccttaa tgatattaga gcgcgggtaa 187140 acgctctcaa caacgaaagt gttggattgg ataacaatac agctagtagt tcaaatccac 187200 cacaattaga aggtaatgtt cctactatta ccgatgactc aggtattgat gaaggtggtt 187260 ggttaactga aatcggatct gtattaatgg accaactgta tggaggtatg gatggcgtta 187320 cattcagagt agaaggcacg gggcctgtat cagattcatt tagtaatagt ttccaacagt 187380 cagctatcgc ctctacgttc aatagtacag tccaagctgt ttcagatttc aagttcaata 187440 tccaaggcgg cgcaactggc attggattaa ttgatggatt aatagaaact actaaacaag 187500 ctgtggctgg ggtggctgct ggatctgtta ttggtaatat accaatggca ctactaggaa 187560 actcccgtgt agaaatacca gaacactggc aagatagtac agcaaacctt catacagaaa 187620 gttttagctt gttctttgaa gctccttatg ctcatcctta ctctattgcc actaacgttt 187680 ttcttccact atctttgatt ctaccgttca ttgtgccatt tagtacaggc ggagctacct 187740 acggttctcc attcatgatt aaatgtttcc aacgtgggaa atcaattgtc cgtatgggaa 187800 tggtaagaaa cgctagcatt acctttggag aaggtcctct tggctggact acagacatga 187860 aacctcgtaa ctgtcgcgta acaattgacg tagcagattt cgaaccaatt ctctctgtcc 187920 cgattagtcg cgtaactaac cctcttgatc ttgctaacat ggcagcacaa tccagtcgtt 187980 atttaggtga tagaggtaag taccaagatt tcatatcaag aaccgctgga gtagattatc 188040 ttgataccgt tcttcgttat gcagatctta atagacgttt aacccgtttt agtacagata 188100 ctaaaaacat gttcaaggct tctagtatcg ctaactcatt atccagttct attgttgcgg 188160 acacggctcg tatatttcta ggtcgcccaa tgcaacgatg atatcgatgt tactgtacta 188220 ttaataaaca taactctact tacccaatta agggtaagta gagtttgaat tagaattctt 188280 attactttct tatttcattt tccctttagt ttcttgcctt taaagatact gattaaagaa 188340 taaaggaagt cactacgttc cactaatatg caatcaaagc cctacccggg catccagggg 188400 tttccatggt aacatataat ataccatcta tttaataaaa taatttaata tagggttaaa 188460 ccttacctaa ccaattgcgg ttaggtaagg agatattagt tttcaaatgc aatagcatta 188520 gggaattgtg ataagaagtg ttctctagca tctacttcct gataaatacc agaagcacat 188580 aagaatggac agtactcagg atagtcagaa aggagtagtt tagcatcatc gctaattaaa 188640 gctactgtaa tgaggtttac agccattccg aactctgttt ggtaaagata ccactgttca 188700 ccaccgacga gctcacagag cttcttaagc agcataccga gctcttgata atcctcagga 188760 ttggtttcag aactaaatgt aaagtttgct aacatccttt caattagatc tggatactta 188820 gcccttacta ctggtaatcc atcagaacta ataatttcaa agatcttgtt aattgattgg 188880 atatcacctt taccaataca gtactctagt gaattgataa tagcatcaac atagtcactc 188940 gtgaacaagt attgattact gaaatcctca aaactctgat acatgccgtt ttgagcagcc 189000 tgtttcaaca tggtattaag aatagagtta acacctgcta aactttggat cttggcgaat 189060 gctggattat tcttaccaag aaaagcggtg agagtatcaa tagcacccat ttcccagcca 189120 tcattaattc gaagcttcat cccatcatcg aaataaagcc cagaagctaa tccacctgtc 189180 atggagttta gttcatccaa gaaacttgaa cctaattgat tcttaatatc tgagatacca 189240 ttaatactgt aaccaagacc ttgggaagct attctcatta atccatctgt gtctactttg 189300 aacccgtctt cataagtcaa aatactacct aaatcaggag aattaagaat acccccgatc 189360 atgtcagtaa cacctgactg aatcttttca atattaatgg atttaaatgt ggtgagtgct 189420 ttggtaagca ttgagtcctt ttcaccaacc aaagctacac cggaactaac tgactctgtt 189480 atgttcttca tcgggttgat caactgatca ctaaacccac tcattgcatc agagattgat 189540 ttagaagcag cttgcaaagg gttatctaaa tcaactcctt tgaatagatt attgttttga 189600 agtaagttca taataaaccc ttaaaaataa aataagtatg aagagtgtcg atacctcctg 189660 ttggaggtat cgaactactc tgattagtct ttatcatcaa ttacatctga acgagagcgt 189720 ctcagaatag tagtttcgga aacatcaaag atttctcctg attctgtttc acattctatt 189780 ttgaatgtta ctcgtttgag tttaagaatc tttaagccag taatgagttt gttaaaactc 189840 aaagtacgac tacaaaagta agcactctgt gcattaccta aggaagtacc tctggctttc 189900 ttaacctcta atggtgtacc ggagtcatct ggatgaatcc agcgtaagta ttcatccatg 189960 taggatttcc acttagctgc gttgactccc atgacatcca tgatatctct aaacattcga 190020 ctcggggtat cagtcagttg ttctttagga acgtagtttt tattctttcc aaatggaact 190080 gtttttgttt tcttttgatc attcatacct gtctctctag gtagaagtcg atgatgttaa 190140 ctagatcaac cagagctagt ctatacaata gactatcaag aaattcatcc tcatctggtg 190200 tcataactac ttcgactact ttatctccgt tgacaagaac tggctccatt agcataactt 190260 gtttttctaa gtatacacta attacaccaa caaacgtttc tatactttct ttatttgaat 190320 accatctaga gaacgatcta gtattctggg ttaaagccac cgacccattc ttcatcatta 190380 cagacttctt tacttccttc ttctctatac ttaatataag acccgctgag ctattgctaa 190440 acgtcttaat gggattgatt gaaccaagta ccaactcttc gttaaaatcg attacaggcg 190500 attttagaat gctttgtaaa gctttaacgt agatatcgtt aaatgctccc gaatcaaagt 190560 cttctaagat ctcagttagt ttaactctaa ttgacttaat cattctttta cgaataaatg 190620 gtatcttagc aagcaacttc ttaaagaaca tgagtaatgt atccttattc tcattagtag 190680 aaaacttctc atgtgtttac catgagaata atatctatct caaaaattat agaaagacta 190740 aaattggagt aaattatgta cgatgatgaa atggaggatt caggtatcct acctcctcca 190800 gtagaaggaa ctaagagtga tgtgatgttg aaggataagg atgtccttat tagtaacatc 190860 aatgctatct tgaagaaaga tcaaaatagc gagacagaaa atgagcttat taatttagtt 190920 cagaaacaac gtaccttgct gttggacatt gctactcaaa cttacattag taagccatct 190980 aactgtaaac tgcttgattc tatcaacact ttgattgggc aattagagaa gtcggtgcgt 191040 gacgacagaa aagaaaaagc taaggcaaaa gagatggaag acaacaagac ttcctttgca 191100 gcttttgtta acgctcttaa tgaagtggct aatggtaaac ttgtaattcc caactatggt 191160 gacatgggta ttattttaga tcccctaaaa cctgtcacac aattggattc cgaaacaatg 191220 atcaaagcag aggaattagc tcaaggtttg attgttgtag attcaaaaga aatcgaagaa 191280 agttttgacg aataaataat ggaatgtatt aaacatcctg acactcgtta gagtgtcagg 191340 atagttggtt tatttggtgt aaatggtacc ctttagataa ttacgacaat taataatgtt 191400 aacttttgcc acatcctccg tctcgatacc gcccaccgca agcgcttttt taagcttttc 191460 aatatctgtt ctggtgaaaa tgtcagaggc tccgccataa tttaaaaacg ttaacgtccc 191520 ttgttcaaaa tgtttggggt ctatagtccc ctttaaacca ttggtaaaat aaacatttat 191580 aaagaagata tctgaattac gtttttccct tactagttcc cggaaaacac taggatcgag 191640 ggtttttatt tcttctattg ttttcgcgtt tagataagaa gaaaaatcgc acatatccac 191700 attttcagga aatgtaaata tcctaatgct aggattatta ccgaactcag tgacgtaaaa 191760 acgtaagttt ccgttaatac agatcccgtg ctggttttta cccagtaacc ttctagggtc 191820 ttcaattttt gcaaaggtga cattcataat ctttcttctc ctagattaat taacattgtt 191880 actctttcac cttaataata taggtttgaa aatatttaga aagacataaa tctcctactc 191940 tcccagctaa gggagagtag gagtatttgc cgttatctaa cgatagtcgt agatagtctt 192000 atcaattgct acaaaggtcg ttttaccgcc aagggagata ttcagcttac tgatgagaga 192060 tctgggagat tcagcatcca ttccttcggg tagttctgtt tgttttgcta agatgtctgg 192120 gacgataaac ttcacgttgc taggttgaca cgttccgtaa tctgaccaat agttcttcat 192180 gtgtttagac aagaagagat catacttaaa gacataatga aaactgttaa gatacttagc 192240 gcgttgatca tcataaggga tgttaacaaa gttaatacca atgttgaact tcaccgcacc 192300 acgtaacgta tcttccagtg ccttctgtct ttctaaactg agctcgaatg ggtatagatt 192360 aactgtcaca ttgaatgtac tcatggacaa catcttacct acaccaaatt ccaactcgcg 192420 tacaatatta aacatatgat tgataagctt actcggaagc acataagcgc accttgagtc 192480 agcaaaatca tcaagagttc ttttatcaaa cctctcttcg aacttctctt gagtaatacc 192540 aagttccggc tgattaaaga tatcgtactt tcgcctagcg tagatttggg agaattgacc 192600 atcccagttg aagttaacat taccagattc taaagcaagt ttgtgaagga tcccgcgacg 192660 tgtatcaaat aagctgtcta gatcagtgta tacgaggatg tccattattc ttccccttta 192720 tctacaccaa tgacattaat tcgatacatc gtgattggag cgtacacagc gagcatataa 192780 cagataggtt taacctgatc tttattatca gcagtaacta ccaacatgtt atctaacccg 192840 gttgttttgt taaccaactc cctagttgac tctactttac gcaaagcttc tgaacagtaa 192900 ggtttagcta atacacgttg aacaaatcta acaaaataat caaatgcatc tggggtttgt 192960 cccaagtcag caattagatt attatagttt tcttcaaacg aaattaaagc ggtgtcataa 193020 agatgatctt tgagtttggt ccaaaataga gaactgtctt tattagcaat aatctcgatc 193080 attgcttctt caacaatgtc ccctagcaga gcttcaacag gatcaactag ttgacctgca 193140 ataggtagct gatccatagt taacctttag cgttgaggtt gttatcaagc atcctaccac 193200 gcagtaagaa gtgtgctgtc tgaagagact taacaccaga tccgcgctgc aaagaagatt 193260 gtgtagttgt ttcaccactg gtaagaatat ctgacttgta agcccgataa gctttaacat 193320 caccaccgcg aacatcaaag agttccttag cagtagtttt caaacctagt gacaacagta 193380 cccgaatctc aggagaacta ataccacctg ctttagaatc acctgtaggt tgtcccgtaa 193440 ggtcttctgt ctcatggtcg ttcttactag caccaaactt cttagcttgc aactgacgct 193500 gtttacgcat ctctgcgtaa cctacaatag ctgtctcagg agtagtgtac tccaaaccag 193560 aatcaggatc agtaataacg agttgttgct ccaacggaat gtttagttct tttgcaaaca 193620 aacaaacatc atcgtaatca atcatctcct tattgtcaaa gttattcaca aagacaggaa 193680 taaagttact gtcacaaata ccattccaaa acgctttaaa ttgctcatcg ttcattttct 193740 taaacagagc tttataaacc aggtgacttc cgccacctgg tgtcatgcgc tttgcgaatg 193800 tcagaatctc ttcttcaatc tcgctacgat gtttcattta cttggtctcg taaccataaa 193860 cagtgaatgt cttagatgct tctgacgctt taatactaac cgcatctaaa taaggttctt 193920 tctggaagtt agcaattacg acaatctcat tgagttgtcc caaataatct tcgacagctt 193980 taatgaaagc ggtcttattt cgattatcgg ttggcataac ttctacacca ggaataccat 194040 acttaccttc tactgttacc acacgcagat taatatcacc agcacgcttt aacagaaacg 194100 ttttaagttt agctagataa gtttcgacat ctttagcttt aaagttgaaa tccggttcta 194160 ccaataccaa tacagaatag tcgtgaagca taattattta atccaataag gttttttctt 194220 attgactgca atctctagaa gttcataaac agtcagtgtg tgtttcttaa tgtgttccgg 194280 gttatcgtgc cagaagtaaa ctgtgttctc aaggatatcg ttccaatcga taccttgttc 194340 tttaacagcg ttataaagct cctctggggt gatacggaag ttagcaggga tgttactcca 194400 gaaggtctga ataaaccaca gttgccaagt gatctcaata gcacggtaca acttaggatc 194460 gcgtgtttca ccctctacca gatcacgtac tgtggtgcgc atcaaactac actcaggata 194520 aagagcacaa gcatgacgaa cagcagaacc cgtcaaccca aagtacttag cttctttgag 194580 catgtgatac atacttatgc cttcctgaat accaagctcc tgagaaccga taaaggagat 194640 gtcaccaccc gagctacctg acttgttacg aaacacagta gtgaaatatt caacaagatc 194700 tggattactc ttagcattaa cttctatctg actctcttta ccacgaggat aagtaacaga 194760 gtgatcagtc tgcttcaata ctgtcccctt gataatctct acaccaatgt gaggaagttt 194820 caacatagct ttaggagcag agagtttctt attgtgacga aggaaggttg agtctttctc 194880 tttaggttta ccgtccatgt tgattacatc agcagattgt gcaatccagt aggaacgaat 194940 acctacccga ggaccgagaa tacagacatc agtcatcagg atacgacgaa ggttaccaat 195000 ctccatatcc cgagtacgct tcttaccacc ttcgtccata tcaccttcat caaactgttt 195060 gaacattagt ttgtcaaaca taacttctga aatggaatca cagataaaga gaatgggatg 195120 ttgaacttga atacgtttac ctgttttttt agaagtccac ggagtatcca tgaagagttc 195180 tttgtacgct tcttgttcag ttttatcttt ggactctgag agtgtttgga tatgtttata 195240 gatattaagt actttgttat gaagctcagt accgtcaaca ccagccgagt taggcatata 195300 aaagaaacgt ttgtcttcga tgttattttc gaaatatttt tcaatgccat acaagcggtt 195360 tacttcttca gcaagccggt tcacatccag agtggattca gtgtcaccat agaggatggt 195420 cgcatgacgg aaccggtgga gtagagcagc gcagtctttg actagtcgac cagtcttctg 195480 ggtgttgtta ccaccagcca atgcattgat cggcatcaag ccaccattca tataccaaac 195540 atcatcttca cccttgatca tgttggtagt ttgcatatca aaaattggag agacgtttaa 195600 cccgatttgc aaattagatt cagcgccgta atctttaatg aaactcaaag cagaaagcat 195660 aatcaaccct tttctcaaat gttatgaatc gattcacact aatgggattt ccatagcatg 195720 actactcgta tttttgatct tgatcagatc actggaaatg aagcacttac cgttggtgag 195780 cgtatttcat ctctgtataa agaattttct ttaggtattg ataagttcaa tgccaaacat 195840 tttaataagt ccattcatac tgttaaaaca gatccaagtg tttggttgaa aagtaataaa 195900 acttatttcg atgtctcgtt caaacatatc caatccccag ttttctttaa cccagcacag 195960 atgagtttca aagagtatac cattttgtta ctccaatcta tcggtgctat gaagctggtt 196020 atgactcaag ctgaagatct ttatcgagca ctaaagaata ctgccgcaac tggtaaggtt 196080 ccttttagta ttcgtaatgg tgatcacttg gttctaatta gcgaactacg tgagaaagta 196140 gaacagctta aagaaagtaa agtattcact cgccctgtct ctgaacttta taccaattgg 196200 tcagaagtag gcgatgtaat caaatacttc aataaagaag ttgttacttt gaaatctcgt 196260 gatgcagaag ttcttgctaa acaagcagat caagttgtag agattgttaa actggttaag 196320 cgtaaggtcg atactaacga gatcattcta tctcctgctg actttgctct gcttaatgag 196380 tctattcaat tcctttcaga taacatgact tttattggtt actcttttac tttgctcgca 196440 gaagtaaccc gagttctcaa tattcattct gaagaattag tgaaactgta aatacctaag 196500 gtagacgatc gtctacctta ggctttatgt ttgcttagta gctaaaacag attttattgt 196560 cagattgctt taaacgcaac agaagtagat taaagaagcc gtcattgtag cgcagggata 196620 ggtggtcact atgtttactg tgcggaccgg agaccgtctt attgaggtta ttgcgaccat 196680 atacagtgag atggttaata tctactgcgt aatagtcgac accatcttcc aagggaatct 196740 ctttgaggta cttaacgatg tactcaagtt cctgatcaag cagtttatga caaaccgtag 196800 agttaggagt aagatcacca aacagtctcc agttatccac acccccaaat gagataaata 196860 ccggagtaat ctgaagtaga tgttgaacga tagaaccatt aaccaagctg atagcaaagt 196920 ccttagctaa actactaaag ctaactgctt tacattccag tagactattg acagcttctt 196980 cgatcaaagt gaacaaacga cggatctctt tatagtcatc accgatataa agtttaatgt 197040 cttcattact cattggagta cgaagaatct gaatatcagt tggttcatca aagatcgggt 197100 tgatcttatc aaaacagaga aacagcttaa atcctttctc ataggtaaca tcaagagtta 197160 gaaaagcatc aaagtctttg ataatgttaa cgtcacgact aacatcttca atacgtttgt 197220 taatgatctc tgccaaacga cgaatctgaa taccagtgat attaacaata ccggaaatac 197280 gttgttgaat aacgtcttta acattatcag gaagttcttt tagatcttca gctaagttag 197340 gtaagaaatc atccacacta ggtttaacag aatacttaaa tggtccatca acttcttcca 197400 gcatttgaag tagttcacct aactcttctt tttcaacaat cttacaaaac ttgttccaga 197460 acttcttact aatagtaaag agatgttcac caagagatat tttgattact tcgtttacag 197520 tatcttcatc tagctccata atgccttctt cagggagtac aaagttagcg aagtgaagaa 197580 aactaacaaa tttatctgaa ttaaaatttt gcatctaagg gttccttatg ttaactggtt 197640 actttacact cagcccaaag gtagagcaag taggttcgtt ttacgttgtt actggtatta 197700 atacgaaatc tctagaactt gacttgaaaa ataactttgg aacaagtgtt attttcaatc 197760 gtcttattac caggattaat gcaagatcat ttaaaattca taagttcttt atggtagaac 197820 ttgcttggat tctagatcat cttactaacc aaaagaataa acgtacagtt gatcgttatt 197880 acgtcggatt gttccgttat aaacaattgt acgatgaagt caaaaccaaa acatggttgg 197940 aaacaactta ccaaactttt cctagttatc ctgttgacga agctcttaaa gagtttacca 198000 taacacctta tcctgaccaa cgggatttcc tggaagaata cagtcggatt aaatacggtt 198060 tccaacttaa ggggtgctta ctagacgcag tagttggctc gggaaagagt ccgacgtctt 198120 tgatttggag taaaatgatc tccaaaggta aattatttat tgtagttcca aaggggttgg 198180 tctattcacc ttgggtaaat gaaatcaata aagtgtataa gaaacctccc aaagtttgga 198240 cttctctgga tggaactaat atcctaaacc atgtggatgc tgagatcttt attattcata 198300 aagaacccat tcgcacagag agttgggaac tggctattaa aaccattact aagaatggtc 198360 aacttccagc caaagtgatt gtagatgaat gtcataacta caatgaacat agttctcagc 198420 aaactaaagg tttaattgat ttctgttctc acccatatat ctctgatgtg ctctttatgt 198480 caggtacacc tattaaagca caaggtaaag aaacgtacgc tttgtttacc atcatcgata 198540 agttctttga taagaatgtc agagataact tcttgaagat gtatggaaga gacaacacat 198600 ttcttaatga gatgcttgct catagactgg gtagaatcaa atatactatc cctgccatta 198660 caaccatgga agctcctcca gaacctgagg taattaaagt ttccttccca ggtgctgagg 198720 cttttaccct gaataacatc cgtactgata tgttgaccta tatcacagaa cgtgttaagt 198780 tctacaaaga acggatgagc acttataaag aagattggtt aatttacgtt aatgatttca 198840 aagaacgtaa gtggagtgac caatctattc aggctagagt aaagacttat gtagactatg 198900 ttaactactt ccaagctaat ggatacaata actttactga tgcagataag tcaaagtttt 198960 gtgcttcagt tgaaaaggaa attgagtcat atttgaaagg tgaagatctt cattacttta 199020 gacacattaa atcagctgtc aagtatgttg gtttaaagat cagaggcgaa gctcttggta 199080 atgtgttagg taaagctcgg atgaatgcca ttaaggaaac cattcgtcac gctaacttac 199140 ctaaacttat tgaaggtgtt aaaaagaaaa ctcttgtata tacttcttat gtggaagtca 199200 ttaaggagtt ggaagattac ttcaaagaag ttggtttaaa atcagtttct gtgtatggta 199260 ataacagtac cgagattgat aaagtaattg gacagttaac tgatgatcca gataccaacc 199320 cattgatcac taccttccaa acactaaggg aaggtaagcc aatgttaatg gctaaccaga 199380 tcatcttaat gaactctcca tttagatcct acgaactgac acagaccatc gctcgggttc 199440 atcgtagagg acaagatgaa aaatgttatg tttatctaat tgatcttgat actggtgagg 199500 aagagaacat cactagtaga tcgattgata tcatggaatg gtctagagaa caggtagaag 199560 ctttacttgg tggtggtaaa ataccaggtg ttgctgaact tggtgttaat acaactgcga 199620 ttggtggtat ggaatcaggt gaatatatct gggacattcc taccatggat cctttgttag 199680 atattccatt ggatgttgtg gaagctgttc caagtatttc tcttatccgt acttctattt 199740 ctgatgtatt ttaaaggact gtatttatga acgtgtttgt ttctgatgta gaacatttcc 199800 aaagtctgtt ggctggtttt gaatcactcg ataacgatat caatgctaaa gatggtgacg 199860 ccgcttacac ccgtacctgc ttgtctttga acggtgtttc ctttaaccag tacgctggta 199920 atgaaggttt cgttcagacc atcaaagatg gtgctgttaa gttctacgag atgattaaat 199980 cctggcttaa gtccgtcaaa gagtttttct ttggtgcggc tggcgccaag caagatcagc 200040 aagtagctaa aactgtaaaa gcagctaatg aacttcctgg taagattaat aaagctctgg 200100 gcgcaatgtc tccggaagaa cgtgagaaag cagaagctaa actgaaaact cacgtcgcta 200160 aacttgaccc ggagacagtt gttcatacag tcggtcttcg taagatgaac gatatttatc 200220 ttatcgataa agacgggctt atgaaagata tcaaaggaac tgctgaaaag atcaaagcag 200280 atttccctga tctctcttct gaccttagta agatcaacac tctttatcag gatatgggta 200340 aactggttgg taagaaagta gaagcagatg ttaagtcttt gactgaagca gcgactctgt 200400 gtgctaagat cgctgaactg cgttctgctt tcaaatccct gcaagctaaa gttacccctg 200460 ctcttgagaa gtctaacgag cagactaaga aacttgcaga aggtaaagct gagaacgaac 200520 aggaccatcg ttactccaag aaagtaacta actatctggc taacctttct agtcacactg 200580 ctaactgcat caagagctgt tctaagtcga ttggtaaaat ggccgtgatc tttaagagtg 200640 ttgctttggc tgtacttagt gaggagcagg atatttttga ttctgttatg actgaagaga 200700 gcgttaaacc tctcgaagta taaaaataaa gcataaagta aacctctact ctccattgga 200760 gagtagaggt tattttcaat attgttactt agcttttccc aactctttca agttatacac 200820 tcgaagagaa gcgcaagagt tacaatgtac caagttgaaa tcaggtgttt gaatcacagt 200880 gtaatacatc acacctgcgt catcgttaaa gtccaatcca atccacactt tgaaatcagt 200940 tatcttatta ttgataatac tgttcaaagc gttacgttca ggaatatcat acctgattgc 201000 cagattgatc ttaacttgtt tcacacaacc tggagcatcg atcatgatag gtactgtcaa 201060 ggtgttatta gtaaagtcag aatggatctt ccatttacct ttagcatctt gttcaaagaa 201120 cttatcagtg atatccaaga aatgctgttt ctggaattgg ttattctcat ccctgcgcat 201180 aaagtacgaa tgaagcattt tcaacttata ttggaaatct ttaattcgat aactcaagcc 201240 aggaggatcg atgaagttaa ccaatacagg atctgtaaca ccagcaatgc tcatagatgc 201300 tttcagatcg ttcttagtca acgttccagg gatggtatcg attactcggc taatttcctt 201360 ggacttaacc attccaacat cagcagctgc taacagattc aacggattag gtttaactgc 201420 tttacagaag tcgtacaact tatctaaaat aacaatcggg gttttggtaa acagtgctga 201480 ataaaagaca tcaggagtag ctttaccata atacgctttc tgaggatcta tccgaccaaa 201540 ctcataccga cgataaccgt tttcatcaat gttgtaaaac tcagacttgt caccagtatt 201600 aaagaaccaa cgagacgcag taactacctt gttaaaatcg ttctcaggat tcttatattc 201660 ttttacagta acaatatcaa tactcactgg ttccccaatg ggtagttcca acattgcttg 201720 agcaagttcc atctgtttgt gagcttgttt cggaccttct ccacctttag cgtaatactc 201780 aaggtcaaag ataatcttac ctttaagttt gccgtaaagt tcccgcgctc tctttacata 201840 gttattatca gcaaactttt cagatacttt attattttcc aagagtttct gaccattgac 201900 actatcgtga atgatcaata ccttctcagc gttttcccgt tccgcatatt ccagcagttc 201960 aatcaaatga gccaagaatg catctacatc agtctcctgt cgaagaccac gaccattcaa 202020 tatcattact tgttcaacgg ggatactttg ataactccca ttcacaaagt aaccgtaacc 202080 ggatggagtg tcttttatca gcttacggga actctcttta gtttgatcgt aggtataacc 202140 atgaccacca gagagtccta cgtttttatc ttttactaat gagctgacaa gataataaac 202200 gatattcata atgttccctg tacgttggtt tacttttaga caactgatgg caagtgtagt 202260 cttaaatcac ctctcttaag ttttggtttg atcaatcaac tcttccctta gcttttttac 202320 ttcttgggtg agttgtttgt tcttacgaag cagtgtgaac acgtcgtttt tcaactcaat 202380 gttctcagac gtaagtctga cacttgcttt gtgttgttca ctgttaatac gaaacaggtc 202440 attgatgttc tcttgttgtt gaacaagatg tacatcaatc ttcctgatcg actgttccat 202500 tgttctagaa tccaagtacc aaatgagaga tcgtaccgtc aatcctatac taaaggtgat 202560 tgcacttatc gcaatgataa ttgaacgcag taacaattga cgcaatcgtt ttaaagagac 202620 ttcacccgta gtcccatgca tcaaatggtc aatccagcga ttaaccaggg ctcgcaatat 202680 aatcagcatc gccactgccc accattttat taactaccaa cattatacgc ttaaaggtca 202740 actatgtcaa ctctttttag ctgttttacc actattactg aactggtact caatggttca 202800 acatctccac ttggagagtt gaccaacgag accaaaacct atgctaagtc tccggattac 202860 tactacttga ataatcaacc ttgtcaactg gtaggttttc gaggtgttaa ccaagcaaat 202920 ccagatgttc gttatgagaa aattcctagc actcacgcta cccctgtgtt gacaatgatt 202980 aattggctct atgaagaagc caagaaagga aacttgtctg aaaactcaca agcgtgtttg 203040 caggctctac aaacgaacta tactcagggt tgggtgtgga aagatgtggc taagatggta 203100 actaacaacg ccatctggtt gccctcaagt atcagcttca cttacgaagt aggtggtgtg 203160 attcatgagt tcaaaatctg gtttgcaaat agtagttttg aaagtgaatt cccgtaccga 203220 gaaatctatg taattcattc cctgccaatt ggtggtattg actactttgc tgagcacaac 203280 tataaagaag tgcaaaatcg cttagcagaa gaaaccactg acaagatcga acaacgtgtg 203340 tacgatttgg ttggtagtca agatccatat actcgtcgta ttgtacttcc ttttgatgtt 203400 tatgatctaa tcaacaaacc acaaaagaat actgcgtact ggacagtgat ttattacggt 203460 aatcctaacg acgcagaaga agaaacttac gaagagattc gtaaacaaat tctggctaac 203520 tctgtgtatc ctgaaactaa atgggaagaa gttattcctg atttgttcaa tccacttgag 203580 tttgtcgtag tcccgtattg gaatgaattg ggtttgatta atgaaactgc acttggatcc 203640 acttacagtc ctatattcac ccaccaaggt ggagacgtgc ttccgaagaa gtatgcggac 203700 ttttatcctc agagcgacat cataaaatcg ctgcaaatcg ttccgcactt gtataaatca 203760 gctaaactgg gtgtagtggg gaaacccacc aacagtgatg gacgaatcct tctgactaat 203820 atcttctctg attatcaact cattccaagt tctgattctc aagctggaat gatgagtaaa 203880 gaaactactt tacttattaa agatctggaa gcgttgttag cagctggaga agtagttact 203940 cctaactcac tccctccaca aggtattcaa cgtgttatca agaacaatcg tctttacttg 204000 agcaaacgtt ctagcaaggt taaattgacc atgatctcac ggtaccaatt tgtacaggat 204060 gggttgatcg atgaataaca ttccatctat ccgttcagct ggtaaatttg ttgctaatgt 204120 tccttatgat aaagttgtta atccagaagt tttctataca gtggaagctg tcagaactct 204180 tcctgagatg caagctttaa acatagatct tttcactact gtgttccagc cggctgggta 204240 caccactgaa caaacacagc aagagatcca aactgctatt gacaacaaag cagttgtagt 204300 ttctttaact agtagaggaa gaggtccagt atacgtactc tctacctttc ttaaaagtat 204360 ccctctttta gatggtgtta tttacgagaa cctagctttg atcgtaagct taggtgcttg 204420 tcctccttct atgaaagatc gacttaatgt agctatagaa catatcaata actacattaa 204480 agagagtgtt gggattaaag aacctaatac tactttaggt actattccga ctcggggata 204540 tgttagtaga gaaactgctg agaactggga gcgttctcgc caattacaaa tcactgaaga 204600 acctagtgac actattaaat tggcagaagc taataagact attagtgaac ttcaaattta 204660 tattaaagag ttagaagcaa ctatcactgg ccaaacaaat ccttaaagta atctaccctc 204720 tactatccct agggatagta gagggattat ttcctttata cacatgctgg atattgatga 204780 acaaacatat ctttagtcaa ctcttccatg cagttaacat cagatgcaat actatcacca 204840 aataacaatc taagtcttcc acgatgtttg ataagtttat atcgtggtcc tatcttgtac 204900 ttagtaacgt gttcatcgtt tatcaaccag agcatcgagc ataacgcctt acgacgccgt 204960 gagggaagtt ctaacagctt atccatgcag ttagatatca attccctctt aatcaaaata 205020 agaacgtctg aagcgctcat atgacgtgtt gtgtaatcag tctcattaat aacaattgca 205080 aaacttattc cttgttcaga ccctttagaa aagaagttaa ctttcagagt ttgacaagag 205140 atctcaattg taattgccgt agtgcgatga ataaacccaa ataccttact acaagtttta 205200 gcatcgaaac ataatacgtt aaatcgatcc ttataaaacg ttatataggg ttctcccaaa 205260 gcaccaaatc taacgccgta aaagccagag ttctcagtgc tcaattcagt aatagtattc 205320 ttaatagaaa catcttgctt cattgtttat ccctagattt tattatttta ttaagcagta 205380 aggtaataag cgtcaggttt gcgttgtttc tgattacgtt ttggttcacc aggatcaaat 205440 tgcataggac atctcatccg tcctttctct agttcttcag ggtaaataat tcctgacata 205500 agaatagata agcagccatc ggtgtgacca gatttgatca attgaaatcc aattgacatt 205560 cttgattcta gaatatctgg atgttccaac attgtggtat tacaggtgtg ccaagctgga 205620 cgtttttcat tgccagtttc tcttaagaat agatcgtcac gaatctgtgc caaagcttct 205680 gaatgaaact tatctgtaat gtcaatagca cattggaacg gttcatattc cacatatact 205740 tccggaccgt atgcgcgggt gccataaact ttcaacattg tactgttctt tctgaccagg 205800 ttaacaacat taccctgacc actaatatcg acagaactac gaagtacaaa ctgaataaca 205860 gtagctggat caatattgga ttttgactca tccattagtt tatacagatt cgttttataa 205920 cgattaagaa cttgattaac ttcatagagg tataaacgtg ggtcgtcttt atattctact 205980 tgactaatac ttaaagctaa agcatttgca attgttttct catttatcat aatcattttc 206040 tattctctct tttctatact taagtaaaga tcatattgta ataacactta aataatatct 206100 atctcaaaaa ttatagaaca aagaaaatag tcccgtaaat tagttattat aaagaaggaa 206160 tgaacctctt agccaattgg ctaagaggtt cgattagaaa gtcttagcga cgtttgttac 206220 ctttacggtt ttcttgaact tgttgaacag gggcttgtac ttcctcttcc tgtacaggtt 206280 cagcttctgc aacactggta tctgtctcag ttactggttc ttcagataca acttcatcct 206340 gtacaacttc ttcagtaact gattgttctt ccccatcggt ttctacttta tgctcaagct 206400 ggacttcttc cagtttagca atgtcgtgat tcataccaac agtttcaaga tcaattgccg 206460 gagtagaagg gatagaatcg atataagtta caaacagttt acctttaagg aagctgtatt 206520 ctacatcaat ttctgcatca gctttagtaa cttcgtcccg ctgttcatgc tcaactactg 206580 agtaatgttt ctcagtgatc tcatagccag tccaggcgag tagctcagaa acttccatag 206640 tcttgtgagc aaggagatag agttgatcat taaacagata gaaacctgga gtagtgatct 206700 ccagaagctc tccagccgct tctacagcgt ttgctttgat cataggagcg agagtaccgg 206760 aacgatactt aacaccttct agcatgtagc tacgaccttt acaagcgatg tctactttcc 206820 actcaccagt ttcttgatca aactgttctt caccaaatac aacttcactg atatccagat 206880 cttcgtaacg acctttggcg atgtccattt gaagttgtac acctgtttgt tgtgcactag 206940 ccaaacggga tttagcaata atgttcagaa agtactgacg aggatcaata agctgagcca 207000 taaatttatc ctttataaac aaaataaaaa tgagggaaac tattacgtta tcccaagttc 207060 atagtatctt ttaaacaaaa aataaacccc aatggggttt attgtaagga ccccgaagga 207120 tcctcactca gcattaactt gcaccggaac ttcgataaca cgttctactg tgttaacggc 207180 ggggaaataa ctagcaattg cacgtgcggg catggctgac agtttgtaag ctaccagggc 207240 agatacaaca gcagtaccag tagactgata accacgcagt gcgtctttgg ctgcatatac 207300 aacagctcca ccagttacgg cggctacagt agcggacagc ttgttaccat tggtggaagc 207360 aagttccaga ccaacagcca aaccaacccc aaccagcgca gctgcgatat tggtgttctc 207420 acccaggata gcctcgtttt tgcttacttc taccatctgt gcaaaggagt tccgttcgag 207480 atccatttga cccagaatag aggaagtgtt tacggcggct ttcagagctt cggtgtttac 207540 agtgttcatg atgttcattc ctatatttgg ttaagttaaa gaagggaata aaattatctc 207600 ttctatttat cactctagta atataggtct gaaaatctat ggatcttaaa tgttaccggt 207660 aaattcccgc tttccagtgg aaacggcata ccgacaaata tctatcttcc ccgccaacac 207720 aaatctgttc accttcttta atcacattgc cttcgtcatc tacccgaaga acgtgtgttg 207780 ctttgcgctt acagaaacac atacctttag tttcttttag ctcctcagca ttagcttgaa 207840 gataagctga agcagggaaa ggattggatt ggaaatcatt acgaagacca aaacacatta 207900 ccggaatatc aaggtaatcc gcaatatcgg taagttgttt agcttgctcc agggtaagga 207960 attggatctc atcaattagg aaacagtcaa ctgtcttatc aaagctttta ccaaagcgaa 208020 ctttttgttc atgttcagac tcgatctcag tttcaaattt gttataacga ttgaaatctg 208080 tgtctttagc accagcgagt cgagctgcta ggaagaacaa gttatctgtt tgactaaaga 208140 tagtagcact agctgataaa ccagcgcggc actttactaa aggttctgta ccttctcgat 208200 tatcaatgct aggttttaga atcatcgggt tctgtccttg ttcccgataa ttgaaatgtg 208260 tcataatcaa actagcagtt ttagaactgt tcataggacc gtagtgtaaa taaagtttct 208320 ttgccataaa tttatccttt ataagttatt aatctaaata ataaagattc tagtaacttc 208380 gcaaattact gcgattatcc aaataagaaa cattaatgga tgaaatatat aattagactt 208440 atatccttga ataaccaaag ctattattga gaaaggtccg tagacagttc caatatgata 208500 aggaacataa tagtaagcta aaatgctaac taatccagct gctataactg tgaatataaa 208560 gtttaataga ttgttttcta accaattaaa gaaatcgttt ttaatagttt tcaattctac 208620 actacagttc atctctttat tcctttaaag aagatatccg ataacattcc ctattgctgc 208680 gcagacaatg ataaacattg tcatagggct tattacccaa cggacatcag taaagagcat 208740 ttgaccaact ctgattaaag tgaaaacaaa taaaaataaa ccaaagtgat cactcttaac 208800 taatgtcatc acaccagcta taaaaactaa actaaccatt agtatcagat tagtgttgct 208860 caataagtta gccctacgcc tcgccgctat attcattttc atttcctcac acaaaaataa 208920 ataacagttt ataaaaagga tgggggagtt gaatctcccc catcaaaccc cgcattaata 208980 cgatttacta gaacgaccca taatgttatt aatcttagcc agtgtcttac agcaagccca 209040 accaccagtc aacgctgtca tggtagcggc agcattatca aacacactag taggaatgtc 209100 ttcttcctca cctgttacca gatcaaggaa tttgatatta tccagtgtgt taccagtgag 209160 gtgaagataa ggttgggtaa gtactgaggt aaaatcaagt accaactctt cttgctctgt 209220 actcaattcc atttggttat acttctccag caatgtttga gctacagtca aataagccca 209280 accgatacca ggaaggatgc cataaataga accagtttta gctgccttca ttgcatcttc 209340 ataacggtag taacgttcag tagcttctga tggaacagta ccagttactt tgattgttac 209400 attgttagca cgcaagcgag agatacgagt aaacaaagac aacccaattg gagtttgttt 209460 gtcaatggca ttcatcttct cataacgagg tacaagttca gaaagaatct cttcagctac 209520 tttactaata gctggatctt ccttattgaa cataacacct tgtgtagtga ggataaatga 209580 acttgtagcc aattctactg cttcgcgatc atagatctct tctacaccta caacaggagt 209640 cactccaacc agtttaccca gttcagatag aatgttgcta ccaagcgaac cagcagcttc 209700 tactttgaac ggaatgaact tagtagtacc ttgaccatta atagattgca gagcactcag 209760 agcaataggt tcaaaactac gtgcaaacat taccacgttc ttataaccgg taaaggcagc 209820 aatgagtttg ttaacagcaa tcatattaac aacaccatca atgatcacta ccggacacat 209880 agcttccaga ggaacattca aaataccagg atgcggggga gtaaagatat ctttaccata 209940 gttaccaggg aacagaatct ccttggtttc cacaatctga tcagcaggaa gagtcggaca 210000 gttttccaaa cggatattgg gattatcatg agtttgataa atctccaata ccttatctac 210060 gatttctgat tcgtagttag aagttgtcat caacatctta cggaatgtat cagaatgaat 210120 atcacctggg ataatcagct tattgatctc ttctaccgct tctttaacca gtttgtcaac 210180 aaaacgtgtt tgagtgaaac ccattttgtt tttaaacatt ttgtaaagat tgtaagtcag 210240 gaacacagta gtagtggtac cgtcaccgac ttccagatcg gttttgatag aaggttcttt 210300 gatcacatct gcaatgaggt tacgacgagc ttcgttgaag tccagcgcct tagcgaccga 210360 tacgccatct ttagtgagct tcggtttatt gagctggttg ataacaacat agcttccgtt 210420 tgggccaagt gttccacaaa ccgactgaaa agcatgttca attacttcat caatgatctt 210480 tctggtttct tctttattgg taaatgtttg ttcggtcaaa atagacatga tcggatcctt 210540 attaaattat aggtttgcgt tactagactt aggttaagca ttaagcgaaa gctttagtga 210600 acttcaatcc aacaggaact ggaacatgtt gtttgagttc aaactcttta cattcttctt 210660 ctgtgaggag tgggtgttgt ttaagaagat gtgaattata aacttcgtta acatcaatgc 210720 gtttataacc ttcacgagta agaacgatat aatcttcggt tcttagttct ttagcaatga 210780 ttccatccac gatccctcgg tcaccaaaga acaaagcttc ggaggaagaa atccaacttt 210840 ccttggcaat aagtttttgt agagttttat cgtctatccc aaaaccttcc ttaaacatat 210900 tgtccatggt ggttgtgatg tggttttgga cacccattgt catattagct tcgtcacggg 210960 aaacggcttg aatgttgtac gatgcctgat gctgcatgaa caaactggtt ctgtaacaaa 211020 gtctcaatga ttgcaaaggg gtaaaaatag cccacgctgc ggaacaaatc gtggacaacc 211080 ctataataac tttcttgcag tgatgagcgt taagtgtgtc cgcgataata gttgccggta 211140 acccatttcc accaccagat ctaactagca gtatcatggg caaggaggga gcctttgatt 211200 gcattagtga attaaaatcg tcagcacctt caaagtccaa ttcaccaaac agagtatatg 211260 ctccccatgg tttcctttct actttatttt cttctacaac tttctgttct tcactcatcg 211320 gggttctcct aaataccttt tgtacttata cacattaata atataggttt gaaaaattat 211380 agactcaata ttttctaata ttgatttcta gttcattatt aatacccatt ttctcaaaga 211440 tctgaaaata aggtttacct tctcccaaac gagaatcgtg ataaactaaa tcccagtcat 211500 cacattctac ctccattcta atatcattat catggatata tgggatatta gtttgatata 211560 cctttgtaat ataaggagca aaggacttgt agacttcacc cccaccgatt atcacaattt 211620 ctttctcttc tttaaaccgt tctaatacag cttctacgga cggtgaaaca attgcatcaa 211680 taaaggcttc agtatttgac gtgagtacca cattggtgcg tccaggaagc ggtctaaaac 211740 gttctgggag agactcgtag gttcgtctac ccatgactac gactttaccc atggtattct 211800 gtttaaacca ttccatgtcc tcaggataac ctttccatgg tagtccattc tgataaccaa 211860 ttgcgtattg ctcatcacta gcaaagatca ttgatacttg acaagtcatc ttaaatccct 211920 aaagaagcat ttgcgaaagt aagttgaaac cctaaactag tgtagaaacc caaagcttct 211980 gggctacgga aatctaaaaa caaaacaatt tccttaaatc cattactaga gaggtcttcc 212040 ttaatcttac tcattaattg agagccaatt ccttctcgtt tgtacatagg ttcaacacag 212100 actgacatca atccacaaat ctctctgtta tctggatgtg gttcagctac agtaattgct 212160 acaggtagat taataattgg gatcattgcg acataaagca cttgggactc gtgtctgagt 212220 aatccgctaa tatctgtgga tagcggagat aaagtctctt gatcacacaa aagttttttg 212280 ttttcaattt cccacttaat taagttgttt tgtaattcaa taactttagc gatctgtttt 212340 tcgttaagta cactattaat ggtattaaga ttaacggaaa ggaatttgag ttccatcttt 212400 attatcctta tagaagacgt tccagtcgac ccataatcaa gcgtgaaagt tgtttaggtg 212460 attgataccg ggtttgattt acataagcgt caagtttgtg ttcttcatca tagataagaa 212520 tttcttcgtg atgagggata atctcaccca gatgtttaga caacggatta tcgtcaatca 212580 agataatttc gtgatctgga taagtttcct ttagaaaagc aactttatca ggttgtactg 212640 aagagtccaa catatggata tcatcgaaga gatgcagaag ttcgttttct tctaaccact 212700 ggcgtgtgta aacttcacca taagggtgga agccacggtg agaacaaatt gaaacgatga 212760 tatcttcacc atgatgttcc aacagagctt ccaaagtacc aatagaaaag gctgaacaca 212820 gcgctgtttt accagcttcc agcatataaa gacctggacc aataatttct ttatccacat 212880 gtttcttgat ccatgctgga tacaacatag tagaaacatt ggattcatta gcaagaacgt 212940 attccagttc ttctttcatg tcattttgtt tgaagaactc tttgatcttt ttattaataa 213000 aggtcccagt ttgggtaata gtgtcgtcca tatcaaaagc taaaaccaat ttactcatta 213060 ttaaaattcc tatattgaaa cataaagagg aggtgggaat cccacctcct aataaattaa 213120 ccaaattgat agtaagagaa acctacgtaa agaacgatga atagaaccat cgttttccat 213180 tccattataa aagcttctct gaaacactgc ttatagggtt tatacaacaa cttcagattc 213240 ttacaataag gaccataagc aagttttgtg tcccttacat caaatagaat aactttcaga 213300 acagatacta ggtaagcaaa caaacaagct agaaacagaa aagtccaaaa caagaaactt 213360 tgattactaa tgaaagaaat aaagtccatt ttttatcctg ctataaagtg aaaagtttta 213420 ccaatcaata caaggaaata cccaaacaca actgtaataa cgttatattg aacaaataac 213480 caaaataaca ttacccgatg ttcacgtact gatttgtgtt cacgtttctt cagatctatg 213540 atgtcgaata taataaagat agttgacacc agaactaccg taatccagta ttctttaacg 213600 aactgaagaa aacccaaagt aaagtctaga attaagttca atacattttc tccatgaaaa 213660 ttacaaatgg caatataatc atcccaaaga taattagtat agaaattcct tttatcactc 213720 atccctccct gaaaccttta ggtctcttat ctttcttatt aatgattaga tcgattaaaa 213780 caccaataag atacaataca ccaattaaca acaaagcacc aaacagcatt gtaatcgacc 213840 tctttattta gttatactgc gatagggaaa cgaattaccg ggccagtatt ttctttacta 213900 taaccttgta ctgagaaatg atcagcagtg taatcaaaga tggtttcagg tttatcaccg 213960 atcaaataca tttgtgctgg tttatcagtg aagatctctg gatgtttctt agcgtaatcg 214020 atctgatctc taacaccggt aatgtgatca gaataaatgt gaacatctat ccctgtatag 214080 ttaacataac gtgcaaccat attacgttgc tgagcaaaca tcatacacag accagcgtat 214140 tcgtttaggt tagcgggatt acctagaacg aaatcattag aacgcatgat gaagctaaga 214200 tccagataga acttaggaac gttatgacga tccattactt cttcagcatg ttcagcccaa 214260 cctttaccag agattggata aagattagca tggatagtgg tatgggagtg tttgaaagtg 214320 ttcagtcgat caccaaaatt cattggtgtc gctgtgagaa cgaacgaaaa atggcaagct 214380 gtgagggaca tcttacctag tttagggttg tctttaggtg cagttttagc aaccggggtg 214440 aatgaagggt tccagcaact aaccaccata cgacgtgaag taggttcatt ctccagtaga 214500 tcgagaacat attgaatttg gtctacttct tcaccatcag gagttttcca gtgtcgccac 214560 tgaacaccat agataggacc caactcccca tcttcatcag caaaacaatt ccagaaagga 214620 acacccattt cttgaagagg tttaacatta gaagatccac tcaacatcca gatcatttct 214680 ttaatcgggt taaatggatt caaataacgt gacttcatca gcggataaga ttcacgaaga 214740 tcgtgttgat aagtatggaa cggaatagaa cgtgtacctg tattagtgcg atcttcctta 214800 actgttccat cttcaagtag agaaagaaga gttttgaaat accacagttc atattggttt 214860 ttgcaatctt tttctttaat accaaacttc ttttcaaact gggtagtgta aacaggttta 214920 actaatacac gttctttaca cgtttcagat tgcataactg attcaggtcg accatcataa 214980 tcgctagtac cacaagaata gacagtacga ggagttgggt attctacctc aggtgaattg 215040 caaaaaggac atttggcagg atctacattc attttcatta cagacgtttc tgacatcatt 215100 attctccagc aaatataggt ttagcagatt tgatttcaat aaactgttta atagactcta 215160 cgaataccat tagatcaagc atgtctttta gcacagttct tgattcaggt attgtgatat 215220 ctttattaat aaataaatct aggtttccct tataatctat tttcatgata gatctgcaaa 215280 attctgtttg caacaacatg ttggtttcac ggtaatctct ttcattagaa agcagagttc 215340 gtagtttgcc gttgttaatt gcatctagaa ctttaataag tttagggact aaatgtcttc 215400 cagcttcttt atgtgtgggg acaatcccta acatcttaac acagaaatca attctgtccg 215460 agttcggata tttttgatag aaggtattat aatcttcttc caattggaat ttaaggtatc 215520 ttactctagt tctaaactca agttcaattc ttattgtaga atcttcgctc atttattatc 215580 tctccatgtt ctatattcac cagatctaat tagctctaaa tcaacaggtc cgtcccttag 215640 gtgatcaata cacacattaa tatatctagg atcttgaatg atcttttcat gtgtatgtcc 215700 atgtagattt agtttaccac gcaattctga atgatgaata ggtgcgtggc ttaaccatag 215760 accggcgcga tggcgatgta gtccgtagat ctcatcataa acttcaataa gatctctagt 215820 tgaattacgg gtatggtcgt ggttacctgc tatgagaatt ttcttaccag gtagcttctt 215880 taggatagac agcccttccc aagtgaaggc tatatcacct aaaagatata tggtagttct 215940 tggagtaact ttatcgttcc aggtatcggc aacgtattct tgatattctt ttaaattagg 216000 gaaccagtcc cttacttgca aagcctttgg atgatctagg tgaagttcgc tccaaaagga 216060 cgaattagac atatttattt ctccaatact ctatactcat tcaattaaat aatatctacc 216120 tgaaaatata tagagtagtt aatttaagat cgtttgaatg atagattatc attcctctta 216180 atatagggga tctggtgagg aaagattatg atttatgaag aacaatatcg ttataaaaag 216240 atttatgatc cattgtttag ttccgtaaag aagtacttgg aaattagact aaacgaaata 216300 atctcttccg gcgatgaaga aaggatcaaa gttgctaaac agagatatga aaatcttcgt 216360 tacatggacg tacaaataga acctggtgtt aagtttgaca atggtaagat cagagcttgt 216420 tttgtatcaa gaaccagagg tttctttcac gcagacgctt tattggaaaa ggtagatttt 216480 gaaactatct tgaaagatca agaggttact ttagaaggag aattcacatc tgaaaccata 216540 ttaactacta ttaaagtgca gggcttagat agcggtgttt actacttaac agatagtaaa 216600 gaaattgttt tagtgttaag tgaacgaaga acaactgtag aagctgtcta taaactcttt 216660 gaagagactc actggtacga gatgacactt actatacctg acagtaaaga tcctgttaca 216720 gagcgttctg ggagtgtttt aattaagtca ttaaacatgg aagataaagt agttcctatt 216780 tattataaac ctcacctaca agaataaaaa taaatatgta aaataaccca acctaaccca 216840 attgggttag gttgggaata ctttattaat cgtgcattac aaaaccattc tcatcaacac 216900 aagcatagat catgttactt gcacctttga gcctgatgtg tttaatcaaa gtaaacggat 216960 ctttaacttt ctttaagata cctattacct gatctatggt aacattctca gaaatgatac 217020 aatcaatgtc aagatcgtaa ggttggtact taaccggaac ttgtgataac accattccaa 217080 actctgtcga gtactcttcc tgaacaacag gatttgtatt gactatatac atcccagaga 217140 taggttgatc tggatttata caagctgata gataagtgat cagatcattt acagtataga 217200 tgttaaatct tgctactggt tcagccattt tacacctcaa aagtaatatg gatctttgat 217260 gagctcctca gttctagctt tgaactcttc cattgttact gatttaaact cgcagccaga 217320 agttagccat gtatctggtg tataattctt ttccagaaac acccagacat ctttaacttt 217380 ctcttttgag cagtgataaa cattaccatt tttaactaaa tcaaaaagag tttgatttag 217440 ttcttggcag gtggaaacat tgcaagaaac tgatttccca aagaacattt cattaggggt 217500 ttctttttgc aaagcagcaa agccgccatg gataggatcg aagcggaaat ctttagccat 217560 gtcgcggtgt tggtaactat cgcgtttgac agttaagaaa agcgctgtag ataatccttc 217620 ttcctcatta atatctatag cgccagctaa atacttaaac atattttctt tcctatactc 217680 aataaggtaa tgtggaacgt tcttcgttac agagtttttc catctcttgc aaagaacatg 217740 gaatccagtt accagtacgt tcagttttac gaggataaat attttcacct tcgataatag 217800 caaacaattt ttgtttgtta tctactgcat tggtgtaaaa tacccgccca gtgtgtttca 217860 gttcaatcaa cttatcaatg attgacttat ctgtttcaac acgacaggaa atactctccc 217920 cgtagaaatg acgttctttc aaattaggag tgaagttagc aaaccctcca ttgaaagcaa 217980 caaaacaagc atcaaacgcc atttctttat gttggtacgc atcacgacgg acagagaaaa 218040 gcagagcatc agctctgccc atacgttctt cccgaccacc attcaactta cttgctactg 218100 gaagtttccc ataaagatat ttcagcattc ctttctccta tacttatttc cagcgatcac 218160 ccagttgtac accgtggttc ttagagagca acattgtaat acagtggtta ggatccaaca 218220 cgtccagata gtagctggaa gaagatccgt ggatagagtc ggccaaacat tccagtttac 218280 gtccgatctc tttatccaga gtacgagcgt aacctttgat agctttcacg taaccttctt 218340 tatggtcaag attaattgag gtttcaaaca ctacagggtc ttgaacccat tccagttcca 218400 gaccaagatc ttcaacttca ccttctactg caaacagaat aaggttggta ggaagcatac 218460 ctactttagg atgcttaact ttaccaacta caacctgacc ttgtttgata cctttgatca 218520 ttatctattc ctttttggta gggttttatt aattggggta ataggtgaaa tcaccagcac 218580 tgctgtaaac ctttacttcg atcacttcgc actcataacg ggagttgtct atcccattga 218640 ataaacgcca ctggtaagtg atcgattgtc cgtacttgag tgacttgttt ttcatccggt 218700 aattacttgg accttcttta caagcaccac ggttaacttc tacattcttt acaaaaatgt 218760 tgtcagccag agacgttaca atgatatcca acaggacacc accgaaatgg tcttcgctca 218820 tcgcactacg aatcttgaac ggggtatcgt tagcaaaagc tgaagaacag aacattacca 218880 gtgttacgaa taatacgttg atcagtttca ttttgatatt tccttatcta gattttacgt 218940 acaaacacac gcattgggaa ctcagttact ggttcaccaa aacaagtagc attccaaaga 219000 gctgtgtcct caggattatc gaccaacctt gcaaccaaga tcagtttgta accttcatga 219060 tatttatcca gattttcaga aagatatttg agaactttac cttcccaatt accaacttcg 219120 gcttctttga tccgatgttc caaataaccc atcagagcgt cttgagattt aaattcaaaa 219180 acaccgtacc cactaacctt gaagtgaaga tcgccttctt gaatcacttc atcgtctttg 219240 aggaaacgga acttgtgttt cagaccaaag agtttctttt tgaagatttg agttttcagt 219300 tcgttcatca tatcctagat tccttaaaca ttatggttga ataacactta aataatatag 219360 ttctaaaact atttggatct taatctttat tacaaaaatc atttaataga ttaagatttt 219420 cattgtaatc tttacgatct tttcgtgatc tctttctatt gtcctttctg attaaccact 219480 ctatatagta ggttgcgcag gttaacatta gacaaagagt aaccatacca aatataaaca 219540 aagtgacttt aaactcttca cctgttttat tgattaagtt tggtaatagc ccaaataaca 219600 tagctgaacc acagaacaag ataatatatt ctcttattct catttatgtt tcctttgacg 219660 tttatgctgt ctgtaaatac ctttgtcatt acgaaaagga gcaggggtcc gacaaccctc 219720 atatccgtta tctttaaata gtggagctac agatttacaa acatcattaa taattcttaa 219780 ctgaccggtt attatatttc ccattattat cacagttctt gtaccagaca aaactacagg 219840 ttgtttaacc gtgatctgac cagtcggttc catgatcaac cccaggctgt cagcttcttc 219900 tggtttcaat cgatcaagat taatgacagg tgtggcttca accccgttgc caatcctccg 219960 ttcgccaacg taccgtaaca ctttgctttt ttcgatatct gtaggtgagt gaataattaa 220020 tatccctttt tctttctcat tcatagctca atccttaata tatttattaa gtaccagaat 220080 ttgggaaggg gttaactgaa gaccttcctt gcgcaaagtt tcatcgattt tatcaatgat 220140 ggctttgtcg agaaatttat catcagatac ttcgctgaag tcaaatgttt cttgatcttc 220200 ggtacccaaa aggaatttct tttcaccttg acgcataaat tcagcaattc ctactttgtt 220260 aacaccttct cgacaatcag tgtgtttatt aagaaaccct ggaataccta caccatcggc 220320 ttcttttaag ccgtaagcca atatcccaaa tcccaactca acactaaaac aaagtttgta 220380 atgcgaagat ccgaaccgtt tatgcaagtc aacaccttca atagtcccag tgacataaat 220440 gtcgtcacct ttgctctctt taaccgcttt aacaaacgta ggaacatttt ggtgttccat 220500 aataaaataa cgatgacgtt taccttggtg aacacatact tgttgtaaca taattcttct 220560 cctagattta aataaatctc tctaaccgaa cattcggtta gagagggtat tgataattat 220620 taaactttct ctacactaac aaatccgcct gcttccagga ttgggtaaat aaatttacca 220680 aactttacac catcaaggtc attcacacct tgccaaaccg ctgcgttaac aaatccttta 220740 cgcaaagcct tacgagggca acacatcaac atcccgacac tctgatcagg gttaatgtaa 220800 gagtaaacct ggacaggtga ttgaccgacg taattggcga ttgcttgacc cagccactta 220860 tatccataac gatcggatac cggactaata cggacagcat cgtggaacgg atgtttatac 220920 ttcttaatcc cacaaacttg cttttgcagt tctgatagat cgtcactagt cttattgtta 220980 acagctacca aaccaaagat aatgttctta aatgacaact ggtaaagcgt gaaatctctt 221040 tccagatcaa gttccgtatt ttgattacct ggtagtgaac tagaaatccg caattgaaat 221100 ttctttgcaa aaagtgatag atctatggga tctataacgt caaacttttc cattacttta 221160 tccttttatt cttgaggaaa caaattcatg atggtttctt ttactgtatt cgtgcgacac 221220 ggaacagaaa cccatttgtc tacattatca acataaaact gaactgagat ttgtggaata 221280 gggagattat caggaatagc aataaccaac cttgctgagc tcccaactga ccacttaggt 221340 gaaaccaggg gaatggagag tccggaaata aactctgaat aactcctgcg ccaatctgtc 221400 atctcatcaa actgttcttc tgtgagttgg ttgtggaacg ctccgtactt gtacttaaca 221460 cgctctttaa aattcaccaa agaactttca aagatattct tatcaccaaa actttgatga 221520 gtaatgtttt tcaaagtttc aataatgata tctcgaacat caattggtgc aaactctcgg 221580 atatcattca tcaactcttt gaacgaactt tcacaaacac taccgcacag cagcagttcg 221640 ttaccagact tgataaaaat ttctttatac tctttaccaa gttcatatag tggtattggg 221700 gctagccaat ccataggcca taaccttagt tcctttacca gctcgactaa aacgtcacct 221760 aaggaactta ttgggttaat atttggatac tgagtctcca aagattttat aaccatttct 221820 ggaaggttct tgatctcttc ctcggcagtt ctaaaaagaa cgtgagttaa aacactatca 221880 tcattataac ttgcttgttc gagttcttgt gaaagatcac cgactatata ggaaagatga 221940 tttttctttt ccttaagaga aagagagttt aaccatttaa cagtactttc gctaagtccg 222000 tcgtatttca tttatgtttc tccatttgac tagtcaaaat acctaaccgg atacaaagat 222060 tatccgcttt accatagatg tcttctaaat atagtaaatg gttttgaaat tgttctggtt 222120 ctacattggc aagataaatt ccatcttcac catctaactg ataaccggta gtgatctctt 222180 tttctgaaaa atcaaaacgc tgatatgtcc agaaccaaga aactttacga tacttgatca 222240 cttgaccatt aggatatgta atctctttcc aatcccatgt tgctagaaca aatctaacat 222300 ggttaccaaa gattaactta tgtagtttct ctttatataa gagaattgca agttgtgttt 222360 tagttttctt taactttacc cacaactcca ttttcttata aaacaacaac tgatgctgta 222420 aaataaatat gttcatatca gtatccagga acttgtaaga aacaagaaat atcggacata 222480 gcaaaatctc ttattccttc acgatcgtaa tcgtaagctc ttaagaaatg ttgtttatct 222540 ttatggtatt ttgatacacc atgccagatg tggacttttg ttgaaacaac tcttctttct 222600 tcgttacctt tgtaattggt atagaagaac tccagtttag gttgttcaac cgcagaacta 222660 ttaggaatag tagaaccagt gattgtcaaa tgtttaaaca actctcctag ttcttcttta 222720 tctaatccaa gtgacttaat agaaacagtt actcctggtg gaataagttc cagtcgattc 222780 aacagatctt tctttataag ttcctgttct ggtgttagaa cgggtttatc tatattgaaa 222840 gacgttacgt tctttggtgt atccttaccg atgtattcga taagttgaca atcagtaaag 222900 gttggggatc ttaccccaac cgattcagaa agaattaaag acagctcttg ttctaattca 222960 ctcattacta tactaatccc cacagcatat catattccaa aataagttta gcttggtcaa 223020 cataagtatc gacctcgccc ttaatttcca gtttgtcaat atactcaccc agcaactgat 223080 ctacaagacc tttaatttca taataccagt cactggggaa cttgaccatg aaagcattta 223140 cgtaatattg ggtatttcca tccttgacta taaagtgtgt tgtagaaacc tcggtcactt 223200 tatctctggt gatgtaaata caaacggtac cttgggattg aatttcaatc cagccggtga 223260 ccaatctttc gttattgttg atttctctac caaaatcttc tttcagtttg ttggaaaatg 223320 attcaacatc cccgttaata atgtcactac cttgatcatt agcgtaccct aatctaaaaa 223380 taggagtaat agttttaata caatcaagga gatgaactcc accaccacct gcgttgtgaa 223440 catcatcaaa acgctcccaa tcgatcatat tgtagagatc agagtggaga ataacatcaa 223500 tggtgtcctg agagatgtgt tctttcatac tctctacaac ttcatcagga agatcatgag 223560 tataaatatc tctcggtcca tgtacagtgc agtgtttacg aatacggata ttcttggtct 223620 gttcccaaga ttccttatac tgttcattaa tgggtgttac atcaacttcc agttgataat 223680 tgaacttacc acccattctc aacagaacgc gtgaccaagt tctccaataa ctggaataaa 223740 caaaaatatc tttatttctt gaaaacatgg tattctctcc tagactatat atttgatcac 223800 ttattaccag gaataaactg ttcaacctta ctctggaacc atttaacagc aacaggaccc 223860 aaagttactt caagatcatc agctttatac attttcttct cctagattat gttatttatt 223920 tttagctaat ttacgattat taattagttc atttagaact ggctgtaagt ctttccattt 223980 atcaggaaga ccttcttcaa ttaactgatc tacaaatttt tctcgttcat cccactcaga 224040 ttgttcagga aatggttctg gatcaaagcg attatcaacg attattttaa ttagttcaga 224100 ctcgctttta gaactacatt tggagcaagg aatatagcca gttccaataa gtttaaattg 224160 ttcaacccca atatgcttaa gttctgtaaa atctttaata caacaaagtg ggaacccgta 224220 aaacaatccg gtaaagaccc agcccggata atctatcata gccttagtta tttccattcc 224280 ttcaatccta gattaaaaaa gattgttact ctttcatctt aataatatat gtttgaaaat 224340 atttggaagt agaaaaataa acattaaaga ttaaataaag aaagatgtca ttcactacgt 224400 tcattccgct atataacaaa caaattaccc taccgggcta accggggttt cctagttagt 224460 tataatatag taaactcaat tgaaaaataa aataaagatg ttttgactat ccttaaaacc 224520 aaaggaaact acgttatggt agctaatgaa cataaggtat taccaaagaa gataaacgat 224580 cctttattct ctattgcgaa acagttcttt aaacaaagac acgaaattgt aaacgaacaa 224640 ggtaacttag tagaacggca tcttgcagat actcgttact ctgatttgaa accagaagac 224700 tttatgatag agtctgtcta tactgacaat gacggttcta agaagatctg tttagtgaag 224760 cgtgataagt catttgctag ggtagatatt ccagtttcta ctgttagtat gttaactatt 224820 gctaaagact ttaatcgaga agttgttgtt tgtaatacct taactgattt caagaataag 224880 tttaatagga aagaagtaca gggtaaactt cttaacttag tttggagaaa tgctctaggt 224940 tattgtgtta aacacgaaga agcttttggt ttagctagat ttaatgaatt aatgggtgac 225000 gtgttctttg agcaatcaga gttctatagg gaagatgaaa cttatattag taagagtaaa 225060 ctaacatctg gtggtgtatt gattaccgat gactcagtag gagtggagcc agttcacttg 225120 tttgttgaag agttagttca agatcaacta gataagaata cggttactga taacttccct 225180 agtacgttaa ctggtaaacg aggtgatgag ttacgtttca ctaacttgtt tactgttgat 225240 ggtgatgacg taactgctaa aacagaatta acttacagaa gtaaaaatgg ttatatttct 225300 ggaaaacaaa cccctaataa actcgagagt gtttttacct ttgtaaaagg ctctgtaagc 225360 tccgtattaa acgacgaagt ggaaattggt atcagtgtag tccatgatga ttacatcttt 225420 tctaaagtcg ttacgttaag ttttacgatt aatcaagatg aagtatctga attaaaagtt 225480 ttagcgcaaa ctgaaagtat tagaacttct actttgtata aactaggaat agttgttaag 225540 tgccaagtga atggtgaaaa tgttattcct gatgtttatc ctagttggtt aacttgtaaa 225600 ctcactaatg acaaatatac cttggataaa acttggaaag atggattact ttacacaggt 225660 gtaccgacta ctattcttcc tgattacaat tctagtttca atgatctaat tattggagag 225720 tttagttatc aggggaataa aggtaacttg tttgtagagt tagaagtaac taaaccttta 225780 ggtgaacagg atcagttaga gttagttaac ttggaaccag ttttaattaa aggtgagaaa 225840 ggtgatattg gaagcgtaac ttaccaggtt aagttaaaga actctccaat cgctttaaat 225900 cagtgcggag ttaacactgg tctggtaggt caaagacaac tgataaacgt cacagacgtc 225960 gatacagagc gttttgaata tgagattgtt caggattcta attcacctgg aatgattata 226020 actgatacta ttaactttgg attaaagtta cctgctagta atggagaact ttattctaga 226080 actgataagt taaatgtaga agttattaaa gtttctaccg tagatcttag acctaggaat 226140 agtttcaata aaactgttga acgttatcag aaaggtcctt taccatttca agtttatatt 226200 aatggtaatg agtcaagtga taaagttaga gatgtgaata ttgagaacag tgaaacttcc 226260 ccggtaataa ttagttttga tacttggaca attcaagata cttggatagt tgttggtggt 226320 gataacgtaa ccactaataa gaaagttaat ttcaaattta aagttttggt agatgggatt 226380 gagaaggatt tctcttggga acaggagttt gagattttag gttacactgg acctgatttg 226440 gttttgttac ctaaatctaa agacttggaa ggaagggaat tggaaactgg ggaatttgat 226500 gtttgtgttt acaataaacg tgaacggata aatactagag tccaatatag acctgaactg 226560 tctactttat atcctaatat caattttaat ccactgaaga aagtaactga acagtttatt 226620 actattggtt atagtttagt ggaacaaggg tcagtggtat cagtattgaa gttcaacgat 226680 agtactaatc ctgatgatat tggtgagata ttagtaaaca gtgagataca accttcttat 226740 ccattgaaag ttaatatgga cggaatggta agtattgagt cgtacttaag taataagctt 226800 aatgtttcag ttaattataa tggaaattct gttttgttaa cagatcctag aataactgta 226860 aatgtaaaat taagttcctc agaagtttta gtcaaatcaa ttgaaccaga tggaatagtt 226920 ttagaaacta ctaagtcagt tcctatggga gaagttgaca tttctgaaat agatttggaa 226980 gttagattat tagatggtgt tagtttatat aggaaggaaa taggtggatt ggtacaagta 227040 acaaggaagg tcatcactgg gataacagtt gaattactaa ctaagaactt tactgctagt 227100 agcaaacaag ctattttgta taaactaaaa gatcaaactg ggtcttatat ctataatgcc 227160 agaacagccg gtgtgggtta tgagaatgga gataataatt taccgaccat tattggaaca 227220 gatagtttca tagaacttgt cgatcctgtt tacgggattt accaatctca cttgatgtta 227280 agtcacttag gtggtaaagc tgggtttatt attagtgtaa acttaggtgg aactgttgtg 227340 cggtcagaca agaacgaaat tgaagttaac ccaactatac ctaaagttac tgatgttaca 227400 gatggaatag ctgttcttaa cgttaattca gatatagatt ttaacgttat gttagataaa 227460 tataatgatc caaatactcc cttaaacact gatgaaattg gaaatattag ttttgatcct 227520 acttacatac atactgttag taaaggactt aaattagtgg aagatggaag atataggatt 227580 aatgtttcta gtacaggtaa aataggaaaa acacaactaa gaattatttt aaccgacaat 227640 gatagaagtt gggatgtagt aatagatata gaaatgaaac gataaattaa ctacacttgc 227700 tctgcggagc aagtgtagtc acaagtattt aaacttagat atttctaggt catcttccac 227760 cagtaaccga acaggtgatc tttgccggtg taaacggcgt gaagctcatt ccagaacctg 227820 aaccttgggc tgttaggcaa gatatggaaa atccactaac tgttttgcta acgttataca 227880 taaccgctgt attacctgtt tctagattac aactaacatt gtaattggtg tttgacatgg 227940 gtatgtcaaa ctctacatta atggttcctt ctagaggatt tgtgacagtt tttatatttt 228000 tacttccact tgccagtaat ttattttcag ttacgaaata agcagtcgtt ccaaataaat 228060 ctgaattcat gactgtttgc aaagactcaa ataaaatcga atctaagagt aaagtccctg 228120 acccacttgc gcgtttaata gaaactgagt gccaaccttt attgggaata acgatacata 228180 atgaatttgt ctcactaatg ttctcagttt ccctattaaa caaattggta ctttttcttt 228240 ttacggctac tggtttggaa ggtaaaaaac tgtatttaaa atgtaagtca gattgcaacg 228300 agttgttatc taagactatt tgtatatcca caccttgtac gctgcttaat ccgttaaaat 228360 aacagactag attgtctgtt tcggcataaa atggtatagt gatccactca tcgagaacaa 228420 ccattgtcgt tttttcattg gtgacgtctc ctaacggtgt agtggaagta gcgttgggta 228480 gaacatttcc acctgccttg gaaacaataa catgggtatt ggggttggct ataataactg 228540 ttcctggccc tgctttttga gtattttcat taagcatcaa agcagcagct aaacgagtac 228600 cgacaatttt gtgcccgttt tcatttaaat gagtgccctc ctgagttatt tcaaccatcg 228660 aatattgatt taaaacatca gaagcagtgt caatccactt acaatcgaaa gtctctgcaa 228720 ccgatcttgc aactgaatta taacttctaa ccaacttagc tgccgagaat tgtgtcccat 228780 caaaacctga taaacttgca aaaaccaccg tacctaacaa tacaacttct ttaccttgaa 228840 gtatttgttt ggctaccatt aaagtcaaca tttctgcaaa attttcaaca ttgtaggaat 228900 tggttttatc agctaaattt tctggatttt taccgttgtt tgtgcaaaaa agcgcgtcgt 228960 taatcccgta acataaaaca gctaataagc tgttagtttt attccgatga cgtaataatg 229020 cgttatacat tctatcaccg gaataaccga gattattacc ggtaattggg ttaaggaaat 229080 tatctacaaa actagatatt gtccattgcg ggtagttatt attataccgc cagtgttcgt 229140 gtactgaatt gtcgccaaaa ccggttggaa cgttggttag gttctgagat agaggagtat 229200 tagggagcgc ttgaccaaac gtttcactat caccgtaaaa atccatagta attggtgttg 229260 tacggtcttt taaaacagca ctaaattttg ctttattgtt gatatgtatt tttcccaact 229320 ttccccaatc tgaaaattgt aacataccgc cgctatttac taaaatagtg atttcatcat 229380 cataatccat ttcagagaaa cttgcacccg gaagtaagtt ccttgatgtt ttaaatgtgt 229440 attctaagcc gttatcagca ataactactc gctgaccatc aaaaaaatct ttggtttcct 229500 tagcgacact gatagttaga atgggacttt taataaaaac cggaacccaa ttattttcat 229560 ctttaggatt aggttgagaa ttgggagcta tttccttcgg aaatgcgcca ttccaacgat 229620 accagttatt atcgccatta ggagctggat tataaacagc tttattacga tccccaggtt 229680 gaagagtgcc accagttaca aaatcaaaac cagctggcat aaatcctgca gattttaaag 229740 ctgcgtcaat tgtaggtttc tcaactccaa atctatctgt ccaagttgga tcagtgctat 229800 tcattgcttt gtcaagatta gtagcgttat cgtagagatc acgctcatca agactcccga 229860 gttcgttacc tgtattaaag ctcataattc tttaccttct atttactgtt aaactaaagt 229920 acataaaatc aataaaagaa tctctctact tctccaatta aggagaagta gagagtattt 229980 attactattt cattttaact aagatcttac caattaacat cttcaaagcg acttgccaga 230040 aaaagaacat tttagaccaa tggaatttat gtccataaga caacatctgt tctttactca 230100 cccaagcttt tgaataagtg tcaatataaa gacctttgtg tttcaatact acatgaccaa 230160 tatttttact agtaattacg taataaattc tagtatctgt aaacagtaac aaataccaga 230220 acgtaagaag tgaactatta gcaagaacgt agtataacac tcctaaaaat gtctttatta 230280 ataggatctg gtctgtattg atagtgagaa aggaaatctt gtaaaatcat taaagttcct 230340 ttagttgtgt aatgttacta tttgcaatgt acacttagtg caggttaatg ttattacatt 230400 attggttatg ttagaggtta caaaagaatc tgttaatcca attcggtagt tcaccgcctg 230460 attagttata tttctactca atatatccat acaaacctcc cacctcactc caccctggtc 230520 actggcaatg accgataatt tactataatt ccaatcattt tttcgatact cgatatctac 230580 tgtagtgacc ccaggattga ccaaagaaac agttctacca gatggcaaca tgttaaattc 230640 tgttacgtta tccactacag ggggaagtat attattcgca atatctgata ttgcaggtag 230700 agctgcttga tttttaccag aaaacatttt aaagctagta ggggcgtaat aaaaattatt 230760 atcgcgaata actaacctta aaaaaggact tagattgttt tgcgaatgaa atggagtggt 230820 aaaattccca tcggtggctt tgatcccaga tacatgtact gatctacact tcccaccttc 230880 ggtaccggct ctaataacag ctatcggtgt attgtagatt tcttccactg acaatacgtt 230940 atctagggta aggtcggaat aaagtataga tttagcgccg ttacaaactc ctactttgac 231000 cttaaccgac tttgctctcc gcgccacaac aagtgccggt ttgacaacgt tgtcacctat 231060 aaaactacca atttctattt caaactggga gccatcaaac acattaacac caatggggtc 231120 attgtatcca ccagataaca ttttaccgat agacccaatc ttaacagtat tcaaactagc 231180 tatcttctta tccccatata tcattgccgg gttatttaca caattcttta tataattgac 231240 atctatatga cagtttacac taccacctgt attgtcagaa ccgtttggtg cattggtgtc 231300 gataccgtca aaatttatcc ctcggtggtc agaacctgaa acacccccgg ttcctctaac 231360 cgatgaatta atagcctttg caaaagaaat aacgttgtta ttatttttat ttgtgtgaaa 231420 atcactaaat tcagtagaga cgtctccgtc taatatcaca tgaacatttt ctactggttt 231480 gtttattctt ttatctccat ctctccaagg gataaagtcg ccattgtcag gatcaaaaaa 231540 gtgagcgaag tttaacatcc cgcctgcttg atcaggtgtt ggaacagatg tgtcagaata 231600 cctgccaata attttacaac acttgctaat aataacagta atgttgtcac gaggaacatt 231660 gacgctacct agcaaatagt aagttccgcc ggcctttaaa acatattcat tccaacgtgt 231720 attcctaaac atccattgta aggagttgcg gttacttcta gccgaaactg gattataaat 231780 agaattaact ttaaccccgt ggttaatatc tgtaggatcg gaaagtaaga aaagtttttt 231840 accattcgcg cactgatgat caccatatcc atccgggatc aaattgggat catctgtaac 231900 aaggtataaa gcaccaccat acgccagtcc ttcatggtaa ctaccagtac gatagatatc 231960 accaactact gtatttaagg tttttagttt agtaagggaa gaaaccgacc taacaggttt 232020 gtttcgataa ctttccacta ctttccaacc ttccccaggt gcacttccag caattacatt 232080 gtaaggaagg tctcccgacc aactatacca agtttgatca gcttggttaa atacgcactt 232140 gtttctatca ccattcttta aaacaccacc tgtggtgaaa tcaaacccag caggagtgaa 232200 tccagccata cgcaaagcgt aatcgatggt tggtcgcttg ttaccaagac gatcagtcca 232260 atagtcttga tcggcattca ttaaaacatc taagttctca cagttatctg aaaaatccaa 232320 gatatctgaa gattctaaat cattaccagt gtcatgattc atatacttat tccttggttt 232380 aatttctaag gtcataaaat cagtaaaata aagaatataa aataactcta cttactccta 232440 aggagtaagt agagtttaaa ttaattatta tattcttctt gacattgttg aaaagagtaa 232500 acaattaaaa gaagagagaa aacattgggg ggaatgaata agttttccaa atgacataaa 232560 gaaatcgtgg tggatgaaat ataaaaaaga aatagaataa ccactccgct tattaagcgg 232620 agtggttatt tttaacatat ttttattgtt tacgttatac gttttattct gatttgctca 232680 tcaacgaatt tattcgttga tgaatttgta ctgtacttaa accttataaa ataagcagca 232740 ccagaattaa tacctagttt aggtgctgaa tttacttcag tgttggaagg gttgacgaat 232800 acagcggtta atgttggtgc ggcaccaatt acacttgttg gtggggtaac tagtggtgta 232860 acaactagtt ccatgttttc accattctta acaagcgaaa ctctatgaca tgacgatgct 232920 gaaactaatt tattttccga tgtagagttt atagaatatg tgttagtgag ttcatacaca 232980 cctgcatcag gaacagctgg catcaaccca tcgcggtttt gtatgtcata cacaatagta 233040 gagtttggta atgtgttcca tgccgctaac ccatatggga cttcttgccg agttactacc 233100 gcattagcga ataccaaaac tggatccaca tcattcagtc ccttccatgt aggagcacct 233160 ggctcacaaa taaaatgaaa atgcgacctt ttaaaccgtg aatatttttc tgtcttggcg 233220 tttaaagtta cagcgtcccc acctatgaga tatgttaatt tttctccatt actataatct 233280 aatgtattcc atctaatatt tttgattgaa ataacattag gataatccgt gatacaatag 233340 actaaatccc agcttgatgc acatgaaacg ccatctatat aaatcccact ttcagtcagg 233400 tcagttagct gagagaaagt tgcgccttgg gctttgttta atacaacaga tggtcggtta 233460 tttgattcag gtccaaagtg gcaaccatcc tttatctgta taacgccccc tatattttca 233520 aaccatccag tgtgaaccaa aggaacatca gtgccatttg ggataaacat ggagtttgtt 233580 acagtgagtc taccgacatt atagtttcca ttaccagggt aattgggttc attagtaaca 233640 ccgtcgtcta atccccattg gataaatgaa tcatattttg accttcctcc ctgttcccaa 233700 ttaaagaaac agccatccat acttccttga tcacatcgcc atgcacgtaa aaaacgctta 233760 acgtttttgt tggtcatgca accatcaaac ttggctacta cagattcaag ttcatgcctg 233820 atgacgtatt cagtgtccgc cgctttgatc ttgtaactac attttccacc gtaattattt 233880 tctctccctg aatcattaaa aataacatac atggtgtcat tggatccgtt cttactttgg 233940 aatcctgata caccaaattc ccaagtgtac tcgaaacacg ctcttgcgtg tattagcggg 234000 aatctaaggt catatgtact aagtggtcta aaggttgaat ctggcattaa tatatcgtag 234060 tttacgaaat ttggtgccga gaattctggg actataaacc cagctgagaa ataataatcg 234120 ccacctggtc cagttaacgc agaacgacta ttgttaggcc actcggttgt taatgtctta 234180 cctagtctgt aaacagcttt cattgcattt ttgaaagcag ctgtactatc tgatagcggt 234240 tcattgggtt ttgctcccgc ccataacacg ttaactacat tacctgtgag tcttcttttc 234300 cagcgtgtgc cagttacact aactatcact gtgcaatcgt catctggggt tgttttatcg 234360 gtatcatctt tatcaaaaac accagcgccc ccatcccctg ggatttctct tccgtatact 234420 gaaattgtag ccgcaacccc tttatatcct cggatataag aatacacccc ggaaccacct 234480 tgggttataa catcgctctt atcaacaaat tcttcactta atggacttgt tcctttagga 234540 acttcaccaa taggaccaga ataacattta cctgttttct catgaagaac tacgtcagta 234600 gttgaagtaa tgcttgcacc ttgttcgaaa gaaccttcaa ctaaatttaa atcagcttct 234660 aaataagttc tacgaagtgc ttctcttgcg tgtactttca acatttcagt tcggttaaac 234720 aacgcttgag cttgtttgtt taaagctccg ttatccccac ctaaactcaa actagtgttc 234780 ttaggaacca catcccaacg actttgacca ataaaagttt cattcatatt ggaaatgtca 234840 gcacgaacgt taaaagcttc tttgataata cctgtgatag ttggcctttt tcttccaaat 234900 cgatcaggat attcattttc ctgactattg acaaagttgt ctaatataag actgttgtct 234960 ttaaatacgt caagatctga cgacgggaaa ggtttattgc tagacattaa tctgttcctc 235020 ttatgaaaat tcaaatcact ttaatagtga ttcctcagaa cggtcataag atcttgaaat 235080 aaaaaacaaa tagaattaat aactctatac tcccaattgg gagtatagag tctagttatt 235140 tgttttaact tagtcgttac acttttgggt gtcaccatca ggggtaatta aacttggttt 235200 agcagaacaa ttcccaggtg tgagaagatc acccagatta gtaatattct cgctatacgc 235260 gcctaaaata cccttcttaa caattgtgtc attctgtttt acatgtaacg tggtatttgg 235320 tatggggtgg ttttgttgcg ctaatgcgtc ataataactt tttagattgt tcataataat 235380 gtctttttaa gtatattgat ctagttaaga tgattctatt tatcactcta gtaatatagg 235440 tttgaaaatc tatggatctt aaatgttagt ctttattccc aattaaggga ataaagactt 235500 tattagttat ttaattgtcc cacagaacac gtttgtgttt atcaattgct tgctgtactg 235560 tttgatcata aattttctta ccttcttccg agaaacattc aaactcttca aggaatttga 235620 tattcctttc aacaaaatca cttagataat aaacacctaa tttatgacca agtgctagat 235680 aaagacggtt aaccatttgt gtggatgaaa agactaatcc atataaacgg tcggcatctc 235740 ttagtaactt accaagatct gtcagcgtgt catctggttt atatgggtat cttgtttgtg 235800 caataatggt acaaacaaaa tcacgatcaa cagcgtgtcc tagtaccgat cgtccattaa 235860 acatgaaact atcaatggta atgcgaatat tcacactgtc atctttgtca ccattgtact 235920 taaagtcgtg ataaataccg gctaccactc cacgatgttt ttcgcttact gaaaacttgt 235980 cattttcttc taacaaattt tccataatca ttcctacgcc aattgcatgg ctgaaattat 236040 ggtagctaca cttaggatct tcagaacaag tactctccaa taaagaaagt tctttcttcc 236100 aacgatgtaa gaaatcatct atatcataac ctttcaaccc aaacaacaaa tcctcttgtt 236160 ccaaacgttc ttgtaaagtc atgtgttatc cttaatataa attccgccag ttaagaagtc 236220 ttcattaata tagttcttcc aatcttcttt acactggaca gaaccaagtt taactctaca 236280 ctctttgtat actacagatc caatatcaac tttacctaga acggtaacag gtttatccac 236340 tccattatgt tcaataacca caacacagag tttgtgataa ctggtttcta catcacagtt 236400 atctacatgc acaactgtac ctttcatata acgtttctga gaggtattag gttgattatc 236460 tttgctaata gctgtgaagc taaagatagt taacagaaat gcaatacaga gtgttacaag 236520 agctttcacg atatatcctt atctagactt aaggttaagt actcaactgt ttgttttaga 236580 aaatatcgac tctaaattag aaccgaaaga aactggaaat tcactatagc gttgagcctg 236640 ctttttctta gcaaacactt ttaatctact ttcagatgga acaaacaagg aattttggaa 236700 atcatgagac tccccattaa taaccaaaac aacaaaatct gcaacaaaac tcaggtcgat 236760 ttctactacc gtctttatat ttttatctag tccttcaaat aactttttgg gcgttatttc 236820 tccttctagg taaattttct tatatgcacc aacaatttca aatacccgag acgtggaaag 236880 tatttgttca ctagcgtgga atccggttac tggtac 236916

Claims (7)

  1. 에로모나스 하이드로필라 균을 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는, 자연으로부터 분리된 미오비리대 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP).
  2. 제1항의 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP)를 유효성분으로 포함하는, 에로모나스 하이드로필라 균에 의해 유발되는 질환 예방용 또는 치료용 조성물.
  3. 제2항에 있어서, 상기 조성물은 약욕제, 또는 사료첨가제 형태로 사용되는 것을 특징으로 하는, 에로모나스 하이드로필라 균에 의해 유발되는 질환 예방용 또는 치료용 조성물.
  4. 제2항에 의한 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP)를 유효성분으로 포함하는 조성물에 사람을 제외한 동물을 담그는 처치를 실시하는 단계를 포함하는, 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
  5. 제4항에 있어서, 상기 조성물이 약욕제 형태인 것을 특징으로 하는, 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
  6. 제2항에 의한 박테리오파지 Aer-HYP-2(수탁번호 KCTC 13258BP)를 유효성분으로 포함하는 조성물을 사람을 제외한 동물에 투여하는 단계를 포함하는, 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
  7. 제6항에 있어서, 상기 조성물이 사료첨가제 형태인 것을 특징으로 하는, 에로모나스 하이드로필라 균에 의해 유발되는 질환을 예방 또는 치료하는 방법.
KR1020170078391A 2017-06-21 2017-06-21 신규한 에로모나스 하이드로필라 박테리오파지 Aer-HYP-2 및 이의 에로모나스 하이드로필라 균 증식 억제 용도 KR101859974B1 (ko)

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