KR101803702B1 - Th-1 반응을 위한 단구성 수지상 세포 및 T 세포를 프라이밍하기 위한 조성물 및 방법 - Google Patents
Th-1 반응을 위한 단구성 수지상 세포 및 T 세포를 프라이밍하기 위한 조성물 및 방법 Download PDFInfo
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- KR101803702B1 KR101803702B1 KR1020147023675A KR20147023675A KR101803702B1 KR 101803702 B1 KR101803702 B1 KR 101803702B1 KR 1020147023675 A KR1020147023675 A KR 1020147023675A KR 20147023675 A KR20147023675 A KR 20147023675A KR 101803702 B1 KR101803702 B1 KR 101803702B1
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- C07K14/52—Cytokines; Lymphokines; Interferons
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31759201P | 2001-09-06 | 2001-09-06 | |
| US60/317,569 | 2001-09-06 | ||
| PCT/US2002/028620 WO2003022215A2 (en) | 2001-09-06 | 2002-09-06 | Compositions and methods for priming monocytic dendritic cells and t cells for th-1 response |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117012621A Division KR20110081341A (ko) | 2001-09-06 | 2002-09-06 | 증가된 인터페론 감마를 생산하는 활성화된 항원 특이적 t 세포를 포함하는 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140116544A KR20140116544A (ko) | 2014-10-02 |
| KR101803702B1 true KR101803702B1 (ko) | 2017-12-01 |
Family
ID=32654226
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147023675A Expired - Lifetime KR101803702B1 (ko) | 2001-09-06 | 2002-09-06 | Th-1 반응을 위한 단구성 수지상 세포 및 T 세포를 프라이밍하기 위한 조성물 및 방법 |
| KR1020047003386A Ceased KR20050027163A (ko) | 2001-09-06 | 2002-09-06 | Th-1 반응을 위한 단구성 수지상 세포 및 T 세포를프라이밍하기 위한 조성물 및 방법 |
| KR1020117012621A Ceased KR20110081341A (ko) | 2001-09-06 | 2002-09-06 | 증가된 인터페론 감마를 생산하는 활성화된 항원 특이적 t 세포를 포함하는 조성물 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020047003386A Ceased KR20050027163A (ko) | 2001-09-06 | 2002-09-06 | Th-1 반응을 위한 단구성 수지상 세포 및 T 세포를프라이밍하기 위한 조성물 및 방법 |
| KR1020117012621A Ceased KR20110081341A (ko) | 2001-09-06 | 2002-09-06 | 증가된 인터페론 감마를 생산하는 활성화된 항원 특이적 t 세포를 포함하는 조성물 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20050059151A1 (https=) |
| EP (3) | EP3653055A1 (https=) |
| JP (3) | JP2005505270A (https=) |
| KR (3) | KR101803702B1 (https=) |
| CN (2) | CN1636229B (https=) |
| AU (1) | AU2008221592B2 (https=) |
| BR (1) | BRPI0212545B8 (https=) |
| CA (1) | CA2459713C (https=) |
| DK (2) | DK2322603T3 (https=) |
| ES (2) | ES2598109T3 (https=) |
| IL (3) | IL160720A0 (https=) |
| MX (1) | MXPA04002147A (https=) |
| NO (2) | NO338147B1 (https=) |
| NZ (1) | NZ531530A (https=) |
| PL (1) | PL372098A1 (https=) |
| PT (2) | PT2322603T (https=) |
| WO (1) | WO2003022215A2 (https=) |
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| US20040057935A1 (en) * | 2002-09-20 | 2004-03-25 | Cedars-Sinai Medical Center | Intratumoral delivery of dendritic cells |
| CN102600461B (zh) * | 2002-12-06 | 2017-07-14 | 西北生物治疗药物公司 | 给予体外部分成熟的树突细胞治疗肿瘤 |
| RU2364625C2 (ru) * | 2003-02-27 | 2009-08-20 | Норсуэст Байотерапьютикс, Инк. | Генерирование дендритных клеток из моноцитарных предшественников дендритных клеток с помощью gm-csf в отсутствие дополнительных цитокинов |
| EP1484064A1 (en) | 2003-06-04 | 2004-12-08 | Gesellschaft für Biotechnologische Forschung | Therapeutical composition containing dentritic cells and use thereof |
| EP1670513B1 (en) * | 2003-10-06 | 2013-01-23 | Cedars-Sinai Medical Center | Cox-2 inhibitors and dendritic cells for use in the treatment of cancer. |
| JP5015601B2 (ja) * | 2003-10-21 | 2012-08-29 | セダーズ−シナイ メディカル センター | 中枢神経系の癌を含む癌の処置のための系および方法 |
| WO2005042737A1 (ja) * | 2003-11-04 | 2005-05-12 | Dnavec Research Inc. | 遺伝子導入された樹状細胞の製造方法 |
| WO2006001120A1 (ja) | 2004-06-24 | 2006-01-05 | Dnavec Research Inc. | マイナス鎖rnaウイルスを含む抗癌剤 |
| KR20220113543A (ko) * | 2005-12-08 | 2022-08-12 | 노쓰웨스트 바이오써라퓨틱스, 인크. | 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법 |
| EP1840206A1 (en) * | 2006-03-28 | 2007-10-03 | Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh | Compositions for the preparation of mature dendritic cells |
| CA2700573C (en) | 2006-09-26 | 2016-11-22 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| CA2700436C (en) | 2006-09-28 | 2017-04-18 | John S. Yu | Cancer vaccines and vaccination methods |
| PL2328923T3 (pl) | 2008-09-02 | 2016-06-30 | Cedars Sinai Medical Center | Epitopy CD133 |
| EP2427485B1 (en) * | 2009-05-07 | 2016-12-07 | ImmunoCellular Therapeutics, Ltd. | Cd133 epitopes |
| NZ628292A (en) * | 2012-02-02 | 2016-09-30 | Neostem Oncology Llc | Pluripotent germ layer origin antigen presenting cancer vaccine |
| KR101704745B1 (ko) * | 2012-05-31 | 2017-02-08 | 제이더블유크레아젠 주식회사 | 수지상세포 성숙화 조성물 및 이를 이용하여 항원 특이적 수지상세포를 제조하는 방법 |
| AU2020203845C1 (en) * | 2012-09-06 | 2022-08-11 | Orbis Health Solutions, Llc | Tumor lysate loaded particles |
| US9744193B2 (en) | 2012-09-06 | 2017-08-29 | Orbis Health Solutions Llc | Tumor lysate loaded particles |
| CN104981258B (zh) | 2012-12-12 | 2017-10-20 | 奥比思健康解决方案有限责任公司 | 用于组织再生的组合物、其制备方法及其用途 |
| ES2662333T3 (es) | 2013-02-14 | 2018-04-06 | Immunocellular Therapeutics Ltd. | Vacunas contra el cáncer y métodos de vacunación |
| CN104936612B (zh) * | 2013-09-05 | 2021-01-01 | 奥比思健康解决方案有限责任公司 | 装载了肿瘤裂解物的微粒 |
| US10166195B2 (en) | 2014-03-05 | 2019-01-01 | Orbis Health Solutions, Llc | Vaccine delivery systems using yeast cell wall particles |
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| IL256522B2 (en) * | 2015-06-30 | 2024-10-01 | Northwest Biotherapeutics Inc | Optimally activated dendritic cells that result in an enhanced or enhanced antitumor immune response |
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| US5366866A (en) * | 1991-07-25 | 1994-11-22 | Duke University | Method of diagnosing ovarian and endometrial cancer with monoclonal antibodies OXA and OXB |
| US5227471A (en) * | 1992-01-30 | 1993-07-13 | Eastern Virginia Medical School Of The Medical College Of Hampton Roads | Monoclonal antibody PD41 that binds to a prostate mucin antigen that is expressed in human prostatic carcinoma |
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