KR101731130B1 - 1종 이상의 생물학적 활성제, 제형화 보조 물질 및 자화가능한 입자를 포함하는 경구 투여 형태 - Google Patents

1종 이상의 생물학적 활성제, 제형화 보조 물질 및 자화가능한 입자를 포함하는 경구 투여 형태 Download PDF

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KR101731130B1
KR101731130B1 KR1020127005600A KR20127005600A KR101731130B1 KR 101731130 B1 KR101731130 B1 KR 101731130B1 KR 1020127005600 A KR1020127005600 A KR 1020127005600A KR 20127005600 A KR20127005600 A KR 20127005600A KR 101731130 B1 KR101731130 B1 KR 101731130B1
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dosage form
magnetic field
magnetized
phases
particles
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KR20120060210A (ko
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베네디크트 하르트비크
노르베르트 빈트하프
멜라니에 리에프케
후안 또메 알깔데
미하엘 담
로사리오 리지오
미하엘 고트샬크
안젤라 올프
크리스티안 마이어
안드레아스 그라익츠케
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에보니크 룀 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020127005600A 2009-09-03 2010-08-30 1종 이상의 생물학적 활성제, 제형화 보조 물질 및 자화가능한 입자를 포함하는 경구 투여 형태 Expired - Fee Related KR101731130B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23961309P 2009-09-03 2009-09-03
DE102009029170.9 2009-09-03
US61/239,613 2009-09-03
DE102009029170 2009-09-03
PCT/EP2010/062641 WO2011026808A1 (en) 2009-09-03 2010-08-30 Oral dosage form, comprising at least one biologically active agent, formulation auxiliary substances and magnetizable particles

Publications (2)

Publication Number Publication Date
KR20120060210A KR20120060210A (ko) 2012-06-11
KR101731130B1 true KR101731130B1 (ko) 2017-05-11

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KR1020127005600A Expired - Fee Related KR101731130B1 (ko) 2009-09-03 2010-08-30 1종 이상의 생물학적 활성제, 제형화 보조 물질 및 자화가능한 입자를 포함하는 경구 투여 형태

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Country Link
US (1) US9050256B2 (enExample)
EP (1) EP2473095B1 (enExample)
JP (1) JP5868319B2 (enExample)
KR (1) KR101731130B1 (enExample)
CN (1) CN102573612B (enExample)
BR (1) BR112012004967B8 (enExample)
CA (1) CA2772708C (enExample)
ES (1) ES2528494T3 (enExample)
IL (1) IL217897A (enExample)
MX (1) MX2012002677A (enExample)
PL (1) PL2473095T3 (enExample)
SI (1) SI2473095T1 (enExample)
WO (1) WO2011026808A1 (enExample)

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JP2014527968A (ja) * 2011-09-14 2014-10-23 ユニバーシティ オブ フロリダ Ｓｍａｒｔ（商標）固体経口剤
DE102011089334A1 (de) 2011-12-21 2013-06-27 Evonik Röhm Gmbh Detektionssystem zur Erfassung magnetischer Objekte im menschlichen Organismus
US11667906B2 (en) * 2014-11-24 2023-06-06 Corning Incorporated Magnetic microcarriers
US11024449B2 (en) * 2017-06-06 2021-06-01 Apple Inc. Multipole elastomeric magnet with magnetic-field shunt
MX2020005764A (es) 2017-12-04 2020-08-20 Evonik Operations Gmbh Enmascaramiento y visualizacion posterior de se?ales de resonancia de espin electronico (esr) utilizando la combinacion de dos materiales.
US10824822B2 (en) * 2019-02-05 2020-11-03 International Business Machines Corporation Magnetic tracking for medicine management
US10679018B1 (en) 2019-02-05 2020-06-09 International Business Machines Corporation Magnetic tracking for medicine management
JP7502741B2 (ja) * 2019-09-26 2024-06-19 スピンセンシングファクトリー株式会社 磁気マーカーおよび磁気マーカー検出システム
KR20230118075A (ko) 2020-10-09 2023-08-10 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 파브리병 치료를 위한 조성물 및 방법
CN112360304A (zh) * 2020-11-06 2021-02-12 炫丽建材江苏有限公司 一种适用于22度免拉手门板的自愈合封边工艺
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
AU2022253899A1 (en) 2021-04-07 2023-10-26 Battelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
KR20250007064A (ko) 2022-04-06 2025-01-13 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 Her2 양성 전이성 유방암 및 기타 암을 치료하기 위한 조성물 및 방법
WO2023196892A1 (en) 2022-04-06 2023-10-12 The Trustees Of The University Of Pennsylvania Passive immunization with anti- aav neutralizing antibodies to prevent off-target transduction of intrathecally delivered aav vectors
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

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DE3740187A1 (de) 1987-11-27 1989-06-08 Urquhart John Verfahren und vorrichtung zum ueberwachen und/oder kontrollieren und/oder registrieren und/oder anzeigen der einnahme von pharmazeutischen praeparaten
DE3940260A1 (de) 1989-03-04 1990-09-13 Werner Weitschies Verfahren zur bestimmung des aufenthaltsortes und der bewegung von objekten durch ihre markierung als magnetisches moment
CN1056049C (zh) 1994-02-02 2000-09-06 湖南省商业科技研究所 一种磁疗食品的制备方法
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Also Published As

Publication number Publication date
HK1168016A1 (en) 2012-12-21
JP5868319B2 (ja) 2016-02-24
BR112012004967A2 (pt) 2016-04-05
CN102573612B (zh) 2015-07-08
WO2011026808A1 (en) 2011-03-10
PL2473095T3 (pl) 2015-04-30
SI2473095T1 (sl) 2015-02-27
CA2772708A1 (en) 2011-03-10
EP2473095B1 (en) 2014-11-12
CA2772708C (en) 2017-07-11
ES2528494T3 (es) 2015-02-10
EP2473095A1 (en) 2012-07-11
US20120143039A1 (en) 2012-06-07
BR112012004967B8 (pt) 2022-07-05
JP2013503831A (ja) 2013-02-04
WO2011026808A8 (en) 2012-03-15
IL217897A (en) 2014-06-30
BR112012004967B1 (pt) 2021-05-11
CN102573612A (zh) 2012-07-11
MX2012002677A (es) 2012-04-11
US9050256B2 (en) 2015-06-09
IL217897A0 (en) 2012-03-29
KR20120060210A (ko) 2012-06-11

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