KR101709141B1 - ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 - Google Patents

ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 Download PDF

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KR101709141B1
KR101709141B1 KR1020107017176A KR20107017176A KR101709141B1 KR 101709141 B1 KR101709141 B1 KR 101709141B1 KR 1020107017176 A KR1020107017176 A KR 1020107017176A KR 20107017176 A KR20107017176 A KR 20107017176A KR 101709141 B1 KR101709141 B1 KR 101709141B1
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methoxy
quinoline
pyrimido
dione
phenyl
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KR20100103661A (ko
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아드난 엠 엠 므잘리
바푸 갓담
다르마 라오 폴리세티
매튜 코스투라
무스타파 규젤
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브이티브이 테라퓨틱스 엘엘씨
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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KR1020107017176A 2008-01-25 2009-01-23 ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 Active KR101709141B1 (ko)

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Application Number Priority Date Filing Date Title
US2361708P 2008-01-25 2008-01-25
US61/023,617 2008-01-25
PCT/US2009/031819 WO2009094528A1 (en) 2008-01-25 2009-01-23 TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-α SYNTHESIS AND AS PDE4 INHIBITORS

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KR20100103661A KR20100103661A (ko) 2010-09-27
KR101709141B1 true KR101709141B1 (ko) 2017-02-22

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US (10) US7964608B2 (https=)
EP (1) EP2244574B1 (https=)
JP (1) JP5406215B2 (https=)
KR (1) KR101709141B1 (https=)
CN (1) CN101925301B (https=)
AU (1) AU2009206368B2 (https=)
BR (1) BRPI0906809A2 (https=)
CA (1) CA2711576C (https=)
EA (1) EA018462B1 (https=)
ES (1) ES2523169T3 (https=)
IL (1) IL206854A (https=)
MA (1) MA32035B1 (https=)
MX (1) MX2010007768A (https=)
NZ (1) NZ586695A (https=)
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KR20200058599A (ko) * 2015-06-17 2020-05-27 화이자 인코포레이티드 삼환형 화합물 및 포스포다이에스터라제 억제제로서 이의 용도
KR102426986B1 (ko) 2015-06-17 2022-07-28 화이자 인코포레이티드 삼환형 화합물 및 포스포다이에스터라제 억제제로서 이의 용도

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