KR101648987B1 - 프로토파낙사디올계 진세노사이드 조성물 및 그의 용도 - Google Patents

프로토파낙사디올계 진세노사이드 조성물 및 그의 용도 Download PDF

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KR101648987B1
KR101648987B1 KR1020107018644A KR20107018644A KR101648987B1 KR 101648987 B1 KR101648987 B1 KR 101648987B1 KR 1020107018644 A KR1020107018644 A KR 1020107018644A KR 20107018644 A KR20107018644 A KR 20107018644A KR 101648987 B1 KR101648987 B1 KR 101648987B1
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ginsenoside
composition
acetaldehyde
ginsenosides
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KR20100111300A (ko
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토마스 이. 데일리
마이클 템페스타
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랩터 세라퓨틱스 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
KR1020107018644A 2008-01-24 2009-01-23 프로토파낙사디올계 진세노사이드 조성물 및 그의 용도 Expired - Fee Related KR101648987B1 (ko)

Applications Claiming Priority (2)

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US2331008P 2008-01-24 2008-01-24
US61/023,310 2008-01-24

Related Child Applications (1)

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KR1020167010378A Division KR20160048228A (ko) 2008-01-24 2009-01-23 프로토파낙사디올계 진세노사이드 조성물 및 그의 용도

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KR20100111300A KR20100111300A (ko) 2010-10-14
KR101648987B1 true KR101648987B1 (ko) 2016-08-17

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KR1020107018644A Expired - Fee Related KR101648987B1 (ko) 2008-01-24 2009-01-23 프로토파낙사디올계 진세노사이드 조성물 및 그의 용도
KR1020167010378A Withdrawn KR20160048228A (ko) 2008-01-24 2009-01-23 프로토파낙사디올계 진세노사이드 조성물 및 그의 용도

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US (1) US8440632B2 (enExample)
EP (1) EP2254569B1 (enExample)
JP (1) JP5523348B2 (enExample)
KR (2) KR101648987B1 (enExample)
CN (1) CN101977600B (enExample)
AU (1) AU2009206753B2 (enExample)
CA (1) CA2713104C (enExample)
DK (1) DK2254569T3 (enExample)
ES (1) ES2400491T3 (enExample)
MY (1) MY160074A (enExample)
NZ (1) NZ587134A (enExample)
TW (1) TWI440463B (enExample)
WO (1) WO2009094177A1 (enExample)

Cited By (1)

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KR20190108777A (ko) * 2018-03-15 2019-09-25 숙명여자대학교산학협력단 진세노사이드 Rb1 및 Rb2를 유효성분으로 함유하는 근육 재생용 조성물

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KR102002147B1 (ko) * 2011-11-22 2019-07-19 더 존스 홉킨스 유니버시티 알코올 독성을 감소시키기 위한 방법들 및 조성물들
KR101446743B1 (ko) * 2012-06-11 2014-10-01 한국생명공학연구원 실리마린을 유효성분으로 포함하는 알콜성 위궤양 예방 및 치료용 조성물
CN102727508B (zh) * 2012-07-15 2014-09-24 浙江大学 人参二醇皂苷组分制备及在防治帕金森氏病中的药物用途
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CN106619669B (zh) * 2016-12-02 2019-03-29 延边大学 原人参二醇皂苷在制备防治炎症疾病的药物中的应用
CN106511360A (zh) * 2016-12-02 2017-03-22 上海芮范生物科技有限公司 一种含有人参皂苷Rg3和水飞蓟素的组合物及药物
CN107441104B (zh) * 2017-08-24 2023-07-21 浙江大学 人参二醇皂苷Rb组分防治糖尿病并发症及代谢紊乱相关疾病的医药用途
KR102138252B1 (ko) * 2018-05-16 2020-07-29 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 효모의 nadph 관련 생합성 경로의 개량을 통한 진세노사이드 생산 증대
US11000537B2 (en) * 2018-10-17 2021-05-11 Amorepacific Corporation Composition comprising novel ginsenoside
KR102672902B1 (ko) * 2018-10-31 2024-06-10 (주)아모레퍼시픽 신규 진세노사이드를 포함하는 숙취 해소용 조성물
US11000538B2 (en) * 2018-10-31 2021-05-11 Amorepacific Corporation Composition for enhancing exercise ability or anti-fatigue comprising novel ginsenoside
CN109758464B (zh) * 2019-03-21 2019-10-25 淮阴师范学院 越南人参皂苷r4在制备神经退行性疾病治疗药物中的应用
AU2020363927A1 (en) 2019-10-10 2022-04-28 Zobrius Pharma As Improved anti-hangover composition, its preparation and uses
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190108777A (ko) * 2018-03-15 2019-09-25 숙명여자대학교산학협력단 진세노사이드 Rb1 및 Rb2를 유효성분으로 함유하는 근육 재생용 조성물
KR102053208B1 (ko) 2018-03-15 2019-12-06 숙명여자대학교 산학협력단 진세노사이드 Rb1 및 Rb2를 유효성분으로 함유하는 근육 재생용 조성물

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US8440632B2 (en) 2013-05-14
JP2011510075A (ja) 2011-03-31
KR20100111300A (ko) 2010-10-14
EP2254569A1 (en) 2010-12-01
HK1144772A1 (en) 2011-03-11
DK2254569T3 (da) 2013-02-25
CN101977600B (zh) 2013-02-27
MY160074A (en) 2017-02-15
JP5523348B2 (ja) 2014-06-18
WO2009094177A1 (en) 2009-07-30
AU2009206753A1 (en) 2009-07-30
EP2254569B1 (en) 2012-11-28
CA2713104A1 (en) 2009-07-30
ES2400491T3 (es) 2013-04-10
AU2009206753B2 (en) 2014-07-03
TWI440463B (zh) 2014-06-11
NZ587134A (en) 2012-04-27
CA2713104C (en) 2016-07-12
US20110065659A1 (en) 2011-03-17
TW200936144A (en) 2009-09-01
KR20160048228A (ko) 2016-05-03
CN101977600A (zh) 2011-02-16

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