KR101626627B1 - 아미도-티오펜 화합물 및 이의 용도 - Google Patents
아미도-티오펜 화합물 및 이의 용도 Download PDFInfo
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- KR101626627B1 KR101626627B1 KR1020107022050A KR20107022050A KR101626627B1 KR 101626627 B1 KR101626627 B1 KR 101626627B1 KR 1020107022050 A KR1020107022050 A KR 1020107022050A KR 20107022050 A KR20107022050 A KR 20107022050A KR 101626627 B1 KR101626627 B1 KR 101626627B1
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| CA2739916A1 (en) * | 2008-10-21 | 2010-04-29 | Merck Sharp & Dohme Corp. | 2,5-disubstituted piperidine orexin receptor antagonists |
| EP2443113A1 (en) * | 2009-06-15 | 2012-04-25 | The University Of Edinburgh | Amido-isothiazole compounds and their use as inhibitors of 11beta-hsd1 for the treatment of metabolic syndrome and related disorders |
| JP5779181B2 (ja) * | 2009-09-16 | 2015-09-16 | ザ ユニバーシティ オブ エディンバラ | (4−フェニル−ピペリジン−1−イル)−[5−(1h−ピラゾール−4−イル)−チオフェン−3−イル]−メタノン化合物及びそれらの使用 |
| WO2011058766A1 (en) * | 2009-11-16 | 2011-05-19 | Raqualia Pharma Inc. | Aryl carboxamide derivatives as ttx-s blockers |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2563780B1 (en) | 2010-04-29 | 2015-05-06 | The University Of Edinburgh | 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11(beta)-hsd1 |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| CN103270029B (zh) | 2010-10-22 | 2016-01-20 | 拜耳知识产权有限责任公司 | 作为农药的杂环化合物 |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| US10039772B2 (en) | 2015-11-13 | 2018-08-07 | Pietro Paolo Sanna | Methods and compositions for treating alcohol use disorders |
| CN106854189A (zh) * | 2015-12-08 | 2017-06-16 | 湖南华腾制药有限公司 | 一种哌嗪化合物的合成方法 |
| JP7334118B2 (ja) | 2017-03-31 | 2023-08-28 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 節足動物を防除するための三環式カルボキサミド類 |
| WO2018177993A1 (de) | 2017-03-31 | 2018-10-04 | Bayer Cropscience Aktiengesellschaft | Pyrazole zur bekämpfung von arthropoden |
| CN111566105A (zh) | 2018-01-08 | 2020-08-21 | 豪夫迈·罗氏有限公司 | 作为MAGL抑制剂的八氢吡啶并[1,2-α]吡嗪类化合物 |
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| WO1998039325A1 (en) | 1997-03-06 | 1998-09-11 | Yamanouchi Pharmaceutical Co., Ltd. | 4,4-difluoro-2,3,4,5-tetrahydro-1h-1-benzazepine derivatives and drug compositions containing them |
| WO2000051608A1 (en) | 1999-03-02 | 2000-09-08 | Merck & Co., Inc. | 3-thienyl and 3-furanyl pyrrolidine modulators of chemokine receptor activity |
| US20060111366A1 (en) | 2003-04-11 | 2006-05-25 | Novo Nordisk A/S | Pharmaceutical use of substituted amides |
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| US5087631A (en) | 1990-12-18 | 1992-02-11 | Glaxo Inc. | Oxathi(SIV)azol-5-one compounds |
| CN1633428A (zh) | 2001-11-22 | 2005-06-29 | 比奥维特罗姆股份公司 | 11-β-羟基类固醇脱氢酶1型抑制剂 |
| SE0202430D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | New Compounds |
| CA2501611A1 (en) * | 2002-10-11 | 2004-04-22 | Astrazeneca Ab | 1,4-disubstituted piperidine derivatives and their use as 11-betahsd1 inhibitors |
| GB0325745D0 (en) | 2003-11-05 | 2003-12-10 | Astrazeneca Ab | Chemical compounds |
| GB0326029D0 (en) | 2003-11-07 | 2003-12-10 | Astrazeneca Ab | Chemical compounds |
| RU2006146608A (ru) | 2004-06-09 | 2008-07-20 | Ф.Хоффманн-Ля Рош Аг (Ch) | ОКТАГИДРОПИРРОЛО[3,4-с]-ПРОИЗВОДНЫЕ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПРОТИВОВИРУСНЫХ АГЕНТОВ |
| WO2006132197A1 (ja) | 2005-06-07 | 2006-12-14 | Shionogi & Co., Ltd. | I型11βヒドロキシステロイド脱水素酵素阻害活性を有するヘテロ環化合物 |
| WO2007053776A1 (en) * | 2005-11-03 | 2007-05-10 | Sgx Pharmaceuticals, Inc. | Pyrimidinyl-thiophene kinase modulators |
| CA2636826C (en) | 2006-01-18 | 2011-11-29 | F.Hoffmann-La Roche Ag | Thiazoles as 11 beta-hsd1 inhibitors |
| PL2076502T3 (pl) | 2006-06-08 | 2011-09-30 | Lilly Co Eli | Podstawione karboksyamidy jako antagoniści receptorów metabotropowych grupy I |
| CA2659155A1 (en) | 2006-07-20 | 2008-01-24 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11.beta.-hsd-1 |
| GB0724251D0 (en) | 2007-12-12 | 2008-02-06 | Univ Edinburgh | Therapeutic compounds and their use |
| US20100022590A1 (en) | 2008-01-17 | 2010-01-28 | Biovitrum Ab (Publ.) | Novel compounds |
| GB0804685D0 (en) | 2008-03-13 | 2008-04-16 | Univ Edinburgh | Therapeutic compounds and their use |
| EP2318403B1 (en) | 2008-08-25 | 2015-12-23 | Boehringer Ingelheim International GmbH | Aryl- and heteroarylcarbonyl derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| EP2443113A1 (en) | 2009-06-15 | 2012-04-25 | The University Of Edinburgh | Amido-isothiazole compounds and their use as inhibitors of 11beta-hsd1 for the treatment of metabolic syndrome and related disorders |
| JP5779181B2 (ja) | 2009-09-16 | 2015-09-16 | ザ ユニバーシティ オブ エディンバラ | (4−フェニル−ピペリジン−1−イル)−[5−(1h−ピラゾール−4−イル)−チオフェン−3−イル]−メタノン化合物及びそれらの使用 |
| EP2563780B1 (en) | 2010-04-29 | 2015-05-06 | The University Of Edinburgh | 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanones as inhibitors of 11(beta)-hsd1 |
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| WO1998039325A1 (en) | 1997-03-06 | 1998-09-11 | Yamanouchi Pharmaceutical Co., Ltd. | 4,4-difluoro-2,3,4,5-tetrahydro-1h-1-benzazepine derivatives and drug compositions containing them |
| WO2000051608A1 (en) | 1999-03-02 | 2000-09-08 | Merck & Co., Inc. | 3-thienyl and 3-furanyl pyrrolidine modulators of chemokine receptor activity |
| US20060111366A1 (en) | 2003-04-11 | 2006-05-25 | Novo Nordisk A/S | Pharmaceutical use of substituted amides |
Also Published As
| Publication number | Publication date |
|---|---|
| IL208081A0 (en) | 2010-12-30 |
| JP5570435B2 (ja) | 2014-08-13 |
| IL208081A (en) | 2017-04-30 |
| CA2716679C (en) | 2016-07-12 |
| CA2716679A1 (en) | 2009-09-17 |
| US20110015178A1 (en) | 2011-01-20 |
| GB0804685D0 (en) | 2008-04-16 |
| AU2009224017B2 (en) | 2014-11-27 |
| US20130012545A1 (en) | 2013-01-10 |
| KR20110008170A (ko) | 2011-01-26 |
| AU2009224017A1 (en) | 2009-09-17 |
| EP2283004A1 (en) | 2011-02-16 |
| US8614209B2 (en) | 2013-12-24 |
| US8299063B2 (en) | 2012-10-30 |
| EP2283004B1 (en) | 2015-05-27 |
| WO2009112845A1 (en) | 2009-09-17 |
| JP2011513476A (ja) | 2011-04-28 |
| DK2283004T3 (en) | 2015-08-24 |
| ES2545489T3 (es) | 2015-09-11 |
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