KR101617812B1 - 비알콜성 지방간 질환을 위한 신규 조성물 - Google Patents

비알콜성 지방간 질환을 위한 신규 조성물 Download PDF

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KR101617812B1
KR101617812B1 KR1020157024370A KR20157024370A KR101617812B1 KR 101617812 B1 KR101617812 B1 KR 101617812B1 KR 1020157024370 A KR1020157024370 A KR 1020157024370A KR 20157024370 A KR20157024370 A KR 20157024370A KR 101617812 B1 KR101617812 B1 KR 101617812B1
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pharmaceutical composition
composition according
fatty liver
sodium
disease
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KR20150118990A (ko
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판카지 파텔
자니 라젠드라쿠마르 하리프라사드
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카딜라 핼쓰캐어 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
KR1020157024370A 2013-04-22 2013-06-25 비알콜성 지방간 질환을 위한 신규 조성물 Active KR101617812B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1468/MUM/2013 2013-04-22
PCT/IN2013/000391 WO2014174524A1 (en) 2013-04-22 2013-06-25 A novel composition for nonalcoholic fatty liver disease (nafld)
IN1468MU2013 IN2013MU01468A (enExample) 2013-04-22 2013-06-25

Publications (2)

Publication Number Publication Date
KR20150118990A KR20150118990A (ko) 2015-10-23
KR101617812B1 true KR101617812B1 (ko) 2016-05-03

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US (3) US20160166539A1 (enExample)
EP (1) EP2988736A1 (enExample)
JP (1) JP6246895B2 (enExample)
KR (1) KR101617812B1 (enExample)
CN (1) CN105377246B (enExample)
AP (1) AP2015008674A0 (enExample)
AU (1) AU2013387996B2 (enExample)
BR (1) BR112015020600A2 (enExample)
CA (1) CA2900435C (enExample)
EA (1) EA201592020A1 (enExample)
GE (1) GEP201706663B (enExample)
HK (1) HK1214968A1 (enExample)
IL (2) IL240183A (enExample)
IN (1) IN2013MU01468A (enExample)
MA (1) MA38385A1 (enExample)
MX (1) MX346943B (enExample)
MY (1) MY180160A (enExample)
PH (1) PH12015501795A1 (enExample)
SG (1) SG11201506218UA (enExample)
UA (1) UA114360C2 (enExample)
WO (1) WO2014174524A1 (enExample)

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EP2670486B1 (en) 2011-01-31 2016-04-06 Cadila Healthcare Limited Treatment for lipodystrophy
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
MY180160A (en) 2013-04-22 2020-11-23 Cadila Healthcare Ltd A novel composition for nonalcoholic fatty liver disease (nafld)
EP3004053B1 (en) 2013-05-30 2021-03-24 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201513857A (zh) 2013-07-05 2015-04-16 Cadila Healthcare Ltd 協同性組成物
IN2013MU02470A (enExample) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
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WO2017064635A2 (en) 2015-10-14 2017-04-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
CN109069503A (zh) * 2016-04-22 2018-12-21 景凯生物科技股份有限公司 纳美芬(nalmefene)、纳曲酮(naltrexone)或其衍生物在治疗(非)酒精性脂肪肝炎(nash)或非酒精性脂肪性肝病(nafld)的应用
US20180243263A1 (en) 2016-12-09 2018-08-30 Cadila Healthcare Ltd. Treatment for primary biliary cholangitis
CN110461328A (zh) 2017-03-28 2019-11-15 吉利德科学公司 治疗肝疾病的治疗组合
GB201710229D0 (en) * 2017-06-27 2017-08-09 Tdeltas Ltd Compounds for new use
TWI814744B (zh) * 2017-10-06 2023-09-11 美商基利科學股份有限公司 包含acc抑制劑之組合療法
CN109675016A (zh) * 2017-10-18 2019-04-26 上海贺普药业股份有限公司 非酒精性脂肪性肝病的治疗药物
CN110934866B (zh) * 2018-09-25 2023-12-01 深圳微芯生物科技股份有限公司 西格列羧及其相关化合物的应用
US12201609B2 (en) * 2018-12-18 2025-01-21 Zydus Lifesciences Limited Saroglitazar for the treatment of hepatocellular carcinoma
WO2020165782A1 (en) * 2019-02-13 2020-08-20 Cadila Healthcare Limited Treatment for polycystic ovarian syndrome (pcos)
CN116546981A (zh) * 2020-12-18 2023-08-04 雀巢产品有限公司 使用至少一种甘氨酸或其衍生物和/或至少一种n-乙酰半胱氨酸或其衍生物以及至少一种百里酚和/或香芹酚的组合物和方法
US20220378786A1 (en) * 2021-05-21 2022-12-01 HepQuant, LLC Methods of defining functional change and slowing progression in chronic liver disease
WO2025238663A1 (en) * 2024-05-16 2025-11-20 Zydus Lifesciences Limited Saroglitazar for the treatment of alcoholic liver diseases

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Also Published As

Publication number Publication date
MX346943B (es) 2017-04-06
US20180185330A1 (en) 2018-07-05
HK1214968A1 (zh) 2016-08-12
IN2013MU01468A (enExample) 2015-04-17
KR20150118990A (ko) 2015-10-23
US20170087127A1 (en) 2017-03-30
AP2015008674A0 (en) 2015-08-31
US20160166539A1 (en) 2016-06-16
IL240183A0 (en) 2015-09-24
IL240183A (en) 2016-08-31
UA114360C2 (uk) 2017-05-25
WO2014174524A8 (en) 2015-10-01
JP6246895B2 (ja) 2017-12-13
CA2900435C (en) 2017-02-14
BR112015020600A2 (pt) 2017-07-18
IL247231A (en) 2017-03-30
CA2900435A1 (en) 2014-10-30
MY180160A (en) 2020-11-23
GEP201706663B (en) 2017-05-10
MX2015010769A (es) 2015-11-26
EA201592020A1 (ru) 2016-05-31
AU2013387996A1 (en) 2015-09-24
CN105377246B (zh) 2018-03-20
CN105377246A (zh) 2016-03-02
EP2988736A1 (en) 2016-03-02
WO2014174524A1 (en) 2014-10-30
US9814697B2 (en) 2017-11-14
SG11201506218UA (en) 2015-09-29
MA38385A1 (fr) 2017-09-29
JP2016515608A (ja) 2016-05-30
PH12015501795A1 (en) 2015-11-09
AU2013387996B2 (en) 2015-12-10

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