EA201592020A1 - Новая композиция для неалкогольной жировой болезни печени (нажбп) - Google Patents
Новая композиция для неалкогольной жировой болезни печени (нажбп)Info
- Publication number
- EA201592020A1 EA201592020A1 EA201592020A EA201592020A EA201592020A1 EA 201592020 A1 EA201592020 A1 EA 201592020A1 EA 201592020 A EA201592020 A EA 201592020A EA 201592020 A EA201592020 A EA 201592020A EA 201592020 A1 EA201592020 A1 EA 201592020A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- nafld
- liver disease
- fatial
- nonalcoholic
- new composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Настоящее изобретение относится к соединению формулы (I) или его фармацевтической приемлемой форме, в котором R имеет значения, указанные в настоящем документе. Кроме того, настоящее изобретение относится к композиции, включающей эффективное терапевтическое количество соединения формулы (I), и способу применения соединений для лечения или профилактики расстройства, такого как неалкогольная жировая болезнь печени (НАЖБП), включающая ожирение печени (стеатоз), неалкогольный стеатогепатит (НАСГ) и цирроз печени (прогрессирующее рубцевание печени).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2013/000391 WO2014174524A1 (en) | 2013-04-22 | 2013-06-25 | A novel composition for nonalcoholic fatty liver disease (nafld) |
IN1468MU2013 IN2013MU01468A (ru) | 2013-04-22 | 2013-06-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201592020A1 true EA201592020A1 (ru) | 2016-05-31 |
Family
ID=49253372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201592020A EA201592020A1 (ru) | 2013-04-22 | 2013-06-25 | Новая композиция для неалкогольной жировой болезни печени (нажбп) |
Country Status (21)
Country | Link |
---|---|
US (3) | US20160166539A1 (ru) |
EP (1) | EP2988736A1 (ru) |
JP (1) | JP6246895B2 (ru) |
KR (1) | KR101617812B1 (ru) |
CN (1) | CN105377246B (ru) |
AP (1) | AP2015008674A0 (ru) |
AU (1) | AU2013387996B2 (ru) |
BR (1) | BR112015020600A2 (ru) |
CA (1) | CA2900435C (ru) |
EA (1) | EA201592020A1 (ru) |
GE (1) | GEP201706663B (ru) |
HK (1) | HK1214968A1 (ru) |
IL (2) | IL240183A (ru) |
IN (1) | IN2013MU01468A (ru) |
MA (1) | MA38385A1 (ru) |
MX (1) | MX346943B (ru) |
MY (1) | MY180160A (ru) |
PH (1) | PH12015501795A1 (ru) |
SG (1) | SG11201506218UA (ru) |
UA (1) | UA114360C2 (ru) |
WO (1) | WO2014174524A1 (ru) |
Families Citing this family (17)
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MY191100A (en) | 2011-01-31 | 2022-05-30 | Cadila Healthcare Ltd | Treatment for lipodystrophy |
US20130158077A1 (en) | 2011-12-19 | 2013-06-20 | Ares Trading S.A. | Pharmaceutical compositions |
WO2014174524A1 (en) | 2013-04-22 | 2014-10-30 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (nafld) |
EP3004053B1 (en) | 2013-05-30 | 2021-03-24 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
TW201513857A (zh) * | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
IN2013MU02470A (ru) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
WO2015033357A2 (en) | 2013-09-06 | 2015-03-12 | Cadila Healthcare Limited | An improved process for the preparation of pyrrole derivatives |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
JP6840853B2 (ja) | 2016-12-09 | 2021-03-10 | カディラ・ヘルスケア・リミテッド | 原発性胆汁性胆管炎の治療 |
US20180280394A1 (en) | 2017-03-28 | 2018-10-04 | Gilead Sciences, Inc. | Methods of treating liver disease |
GB201710229D0 (en) * | 2017-06-27 | 2017-08-09 | Tdeltas Ltd | Compounds for new use |
CA3077273A1 (en) * | 2017-10-06 | 2019-04-11 | Gilead Sciences, Inc. | Combination therapy comprising an acc inhibitor |
CN109675016A (zh) * | 2017-10-18 | 2019-04-26 | 上海贺普药业股份有限公司 | 非酒精性脂肪性肝病的治疗药物 |
CN110934866B (zh) * | 2018-09-25 | 2023-12-01 | 深圳微芯生物科技股份有限公司 | 西格列羧及其相关化合物的应用 |
US20220071954A1 (en) * | 2018-12-18 | 2022-03-10 | Cadila Healthcare Limited | Saroglitazar for the treatment of hepatocellular carcinoma |
EP3923932A4 (en) * | 2019-02-13 | 2022-11-16 | Cadila Healthcare Limited | TREATMENT OF POLYCYSTIC OVARY SYNDROME (PCOS) |
US20220378786A1 (en) * | 2021-05-21 | 2022-12-01 | HepQuant, LLC | Methods of defining functional change and slowing progression in chronic liver disease |
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MY191100A (en) | 2011-01-31 | 2022-05-30 | Cadila Healthcare Ltd | Treatment for lipodystrophy |
WO2014174524A1 (en) | 2013-04-22 | 2014-10-30 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (nafld) |
EP3004053B1 (en) | 2013-05-30 | 2021-03-24 | Cadila Healthcare Limited | A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities |
TW201513857A (zh) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
IN2013MU02470A (ru) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
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-
2013
- 2013-06-25 WO PCT/IN2013/000391 patent/WO2014174524A1/en active Application Filing
- 2013-06-25 AP AP2015008674A patent/AP2015008674A0/xx unknown
- 2013-06-25 UA UAA201509744A patent/UA114360C2/uk unknown
- 2013-06-25 CA CA2900435A patent/CA2900435C/en not_active Expired - Fee Related
- 2013-06-25 JP JP2016505927A patent/JP6246895B2/ja active Active
- 2013-06-25 IN IN1468MU2013 patent/IN2013MU01468A/en unknown
- 2013-06-25 CN CN201380075905.9A patent/CN105377246B/zh active Active
- 2013-06-25 EP EP13767126.9A patent/EP2988736A1/en not_active Withdrawn
- 2013-06-25 MX MX2015010769A patent/MX346943B/es active IP Right Grant
- 2013-06-25 AU AU2013387996A patent/AU2013387996B2/en not_active Ceased
- 2013-06-25 BR BR112015020600A patent/BR112015020600A2/pt not_active IP Right Cessation
- 2013-06-25 MA MA38385A patent/MA38385A1/fr unknown
- 2013-06-25 KR KR1020157024370A patent/KR101617812B1/ko active IP Right Grant
- 2013-06-25 GE GEAP201313941A patent/GEP201706663B/en unknown
- 2013-06-25 EA EA201592020A patent/EA201592020A1/ru unknown
- 2013-06-25 SG SG11201506218UA patent/SG11201506218UA/en unknown
- 2013-06-25 US US14/782,609 patent/US20160166539A1/en not_active Abandoned
- 2013-06-25 MY MYPI2015002026A patent/MY180160A/en unknown
-
2015
- 2015-07-28 IL IL240183A patent/IL240183A/en not_active IP Right Cessation
- 2015-08-14 PH PH12015501795A patent/PH12015501795A1/en unknown
-
2016
- 2016-03-15 HK HK16103017.5A patent/HK1214968A1/zh unknown
- 2016-08-11 IL IL247231A patent/IL247231A/en not_active IP Right Cessation
- 2016-11-04 US US15/343,859 patent/US9814697B2/en active Active
-
2017
- 2017-11-02 US US15/801,738 patent/US20180185330A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR101617812B1 (ko) | 2016-05-03 |
US20160166539A1 (en) | 2016-06-16 |
BR112015020600A2 (pt) | 2017-07-18 |
US9814697B2 (en) | 2017-11-14 |
IL240183A (en) | 2016-08-31 |
US20170087127A1 (en) | 2017-03-30 |
SG11201506218UA (en) | 2015-09-29 |
WO2014174524A8 (en) | 2015-10-01 |
UA114360C2 (uk) | 2017-05-25 |
GEP201706663B (en) | 2017-05-10 |
CN105377246A (zh) | 2016-03-02 |
US20180185330A1 (en) | 2018-07-05 |
KR20150118990A (ko) | 2015-10-23 |
AP2015008674A0 (en) | 2015-08-31 |
AU2013387996B2 (en) | 2015-12-10 |
IN2013MU01468A (ru) | 2015-04-17 |
PH12015501795A1 (en) | 2015-11-09 |
MY180160A (en) | 2020-11-23 |
HK1214968A1 (zh) | 2016-08-12 |
CA2900435A1 (en) | 2014-10-30 |
CA2900435C (en) | 2017-02-14 |
JP6246895B2 (ja) | 2017-12-13 |
IL247231A (en) | 2017-03-30 |
IL240183A0 (en) | 2015-09-24 |
EP2988736A1 (en) | 2016-03-02 |
MX2015010769A (es) | 2015-11-26 |
JP2016515608A (ja) | 2016-05-30 |
MA38385A1 (fr) | 2017-09-29 |
CN105377246B (zh) | 2018-03-20 |
WO2014174524A1 (en) | 2014-10-30 |
MX346943B (es) | 2017-04-06 |
AU2013387996A1 (en) | 2015-09-24 |
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