MX2021002305A - Tratamiento de trastornos del higado. - Google Patents
Tratamiento de trastornos del higado.Info
- Publication number
- MX2021002305A MX2021002305A MX2021002305A MX2021002305A MX2021002305A MX 2021002305 A MX2021002305 A MX 2021002305A MX 2021002305 A MX2021002305 A MX 2021002305A MX 2021002305 A MX2021002305 A MX 2021002305A MX 2021002305 A MX2021002305 A MX 2021002305A
- Authority
- MX
- Mexico
- Prior art keywords
- treating liver
- liver disorders
- disorders
- manifestations
- symptoms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
En este documento se proporcionan métodos y composiciones para tratar trastornos del hígado, incluyendo sin limitación esteatohepatitis no alcohólica, y síntomas y manifestaciones de los mismos, en un paciente. En consecuencia, en este documento se utilizan compuestos de fórmulas (I), (II), etc., como se divulga en este documento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2018/103349 WO2020042114A1 (en) | 2018-08-30 | 2018-08-30 | Treating liver disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021002305A true MX2021002305A (es) | 2021-05-31 |
Family
ID=69643368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021002305A MX2021002305A (es) | 2018-08-30 | 2018-08-30 | Tratamiento de trastornos del higado. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20210244744A1 (es) |
EP (1) | EP3844156A4 (es) |
JP (1) | JP2022508402A (es) |
KR (1) | KR20210052507A (es) |
CN (1) | CN112771026A (es) |
AU (1) | AU2018438845A1 (es) |
CA (1) | CA3110256A1 (es) |
IL (1) | IL281052A (es) |
MX (1) | MX2021002305A (es) |
SG (1) | SG11202101863YA (es) |
WO (1) | WO2020042114A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114667142A (zh) * | 2019-11-08 | 2022-06-24 | 拓臻制药公司 | 治疗肝脏病症 |
CN115811972A (zh) * | 2020-05-13 | 2023-03-17 | 拓臻制药公司 | 肝脏病症的组合治疗 |
EP4149453A4 (en) * | 2020-05-13 | 2024-05-22 | Terns Pharmaceuticals, Inc. | COMBINATION TREATMENT OF LIVER DISEASES |
IL300853A (en) | 2020-08-25 | 2023-04-01 | Lilly Co Eli | SSAO inhibitor polymorphs |
IL302099A (en) * | 2020-10-15 | 2023-06-01 | Lilly Co Eli | FXR agonist polymorphs |
MX2023005884A (es) * | 2020-11-23 | 2023-06-26 | Aclaris Therapeutics Inc | Metodos para sintetizar compuestos de piridinona-piridinilo sustituidos. |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1696910A4 (en) * | 2003-09-26 | 2009-12-09 | Smithkline Beecham Corp | COMPOSITIONS AND METHOD FOR THE TREATMENT OF FIBROSIS |
TW200906823A (en) * | 2007-07-16 | 2009-02-16 | Lilly Co Eli | Compounds and methods for modulating FXR |
JP2012505849A (ja) * | 2008-10-15 | 2012-03-08 | エフ.ホフマン−ラ ロシュ アーゲー | 新規なベンズイミダゾール誘導体 |
JP2018519246A (ja) * | 2015-04-28 | 2018-07-19 | ジエンス ハンセン ファーマセウティカル グループ カンパニー リミテッド | コール酸誘導体、及びその製造方法及び医薬用途 |
WO2017078928A1 (en) * | 2015-11-06 | 2017-05-11 | Salk Institute For Biological Studies | Fxr agonists and methods for making and using |
SG11201808607SA (en) * | 2016-03-28 | 2018-11-29 | Intercept Pharmaceuticals Inc | Medicine obtained by combining fxr agonist and arb |
WO2017167934A1 (en) * | 2016-03-30 | 2017-10-05 | Genfit | Non-invasive diagnostic of non-alcoholic steatohepatitis |
US20220387414A1 (en) * | 2019-11-08 | 2022-12-08 | Terns Pharmaceuticals Inc. | Treating liver disorders |
EP4149453A4 (en) * | 2020-05-13 | 2024-05-22 | Terns Pharmaceuticals, Inc. | COMBINATION TREATMENT OF LIVER DISEASES |
TW202333726A (zh) * | 2021-11-11 | 2023-09-01 | 美商拓臻製藥公司 | 以ssao抑制劑治療肝病 |
-
2018
- 2018-08-30 AU AU2018438845A patent/AU2018438845A1/en active Pending
- 2018-08-30 MX MX2021002305A patent/MX2021002305A/es unknown
- 2018-08-30 WO PCT/CN2018/103349 patent/WO2020042114A1/en unknown
- 2018-08-30 EP EP18931946.0A patent/EP3844156A4/en active Pending
- 2018-08-30 SG SG11202101863YA patent/SG11202101863YA/en unknown
- 2018-08-30 KR KR1020217009346A patent/KR20210052507A/ko not_active Application Discontinuation
- 2018-08-30 CN CN201880097022.0A patent/CN112771026A/zh active Pending
- 2018-08-30 US US17/271,554 patent/US20210244744A1/en active Pending
- 2018-08-30 CA CA3110256A patent/CA3110256A1/en active Pending
- 2018-08-30 JP JP2021536122A patent/JP2022508402A/ja active Pending
-
2021
- 2021-02-23 IL IL281052A patent/IL281052A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL281052A (en) | 2021-04-29 |
KR20210052507A (ko) | 2021-05-10 |
EP3844156A1 (en) | 2021-07-07 |
EP3844156A4 (en) | 2022-06-08 |
JP2022508402A (ja) | 2022-01-19 |
US20210244744A1 (en) | 2021-08-12 |
CN112771026A (zh) | 2021-05-07 |
SG11202101863YA (en) | 2021-03-30 |
WO2020042114A1 (en) | 2020-03-05 |
AU2018438845A1 (en) | 2021-04-01 |
CA3110256A1 (en) | 2020-03-05 |
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