IL281052A - Treatment of liver disorders - Google Patents
Treatment of liver disordersInfo
- Publication number
- IL281052A IL281052A IL281052A IL28105221A IL281052A IL 281052 A IL281052 A IL 281052A IL 281052 A IL281052 A IL 281052A IL 28105221 A IL28105221 A IL 28105221A IL 281052 A IL281052 A IL 281052A
- Authority
- IL
- Israel
- Prior art keywords
- treating liver
- liver disorders
- disorders
- treating
- liver
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2018/103349 WO2020042114A1 (en) | 2018-08-30 | 2018-08-30 | Treating liver disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL281052A true IL281052A (en) | 2021-04-29 |
Family
ID=69643368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL281052A IL281052A (en) | 2018-08-30 | 2021-02-23 | Treatment of liver disorders |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210244744A1 (es) |
| EP (1) | EP3844156A4 (es) |
| JP (1) | JP2022508402A (es) |
| KR (1) | KR20210052507A (es) |
| CN (1) | CN112771026A (es) |
| AU (1) | AU2018438845A1 (es) |
| CA (1) | CA3110256A1 (es) |
| IL (1) | IL281052A (es) |
| MX (1) | MX2021002305A (es) |
| SG (1) | SG11202101863YA (es) |
| WO (1) | WO2020042114A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022005407A (es) * | 2019-11-08 | 2022-05-24 | Terns Pharmaceuticals Inc | Tratamiento de trastornos hepaticos. |
| IL298145A (en) * | 2020-05-13 | 2023-01-01 | Terns Pharmaceuticals Inc | Combined treatment of liver disorders |
| MX2022014238A (es) * | 2020-05-13 | 2023-04-11 | Terns Pharmaceuticals Inc | Tratamiento combinado de trastornos hepáticos. |
| CA3193057A1 (en) | 2020-08-25 | 2022-03-03 | Eli Lilly And Company | Polymorphs of an ssao inhibitor |
| AU2021359895A1 (en) * | 2020-10-15 | 2023-06-15 | Eli Lilly And Company | Polymorphs of an fxr agonist |
| EP4247380A1 (en) * | 2020-11-23 | 2023-09-27 | Aclaris Therapeutics, Inc. | Methods of synthesizing substituted pyridinone-pyridinyl compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070015796A1 (en) * | 2003-09-26 | 2007-01-18 | Smithkline Beecham Corporation | Compositions and methods for treatment of fibrosis |
| TW200906823A (en) * | 2007-07-16 | 2009-02-16 | Lilly Co Eli | Compounds and methods for modulating FXR |
| WO2010043513A1 (en) * | 2008-10-15 | 2010-04-22 | F. Hoffmann-La Roche Ag | New benzimidazole derivatives |
| CN107250150B (zh) * | 2015-04-28 | 2019-11-22 | 江苏豪森药业集团有限公司 | 胆酸衍生物及其制备方法和医药用途 |
| WO2017078928A1 (en) * | 2015-11-06 | 2017-05-11 | Salk Institute For Biological Studies | Fxr agonists and methods for making and using |
| CA3019496A1 (en) * | 2016-03-28 | 2017-10-05 | Intercept Pharmaceuticals, Inc. | Medicine obtained by combining fxr agonist and arb |
| JP7418959B2 (ja) * | 2016-03-30 | 2024-01-22 | ジェンフィ | 非アルコール性脂肪性肝炎の非侵襲的診断 |
| US20220387414A1 (en) * | 2019-11-08 | 2022-12-08 | Terns Pharmaceuticals Inc. | Treating liver disorders |
| IL298145A (en) * | 2020-05-13 | 2023-01-01 | Terns Pharmaceuticals Inc | Combined treatment of liver disorders |
| EP4429637A1 (en) * | 2021-11-11 | 2024-09-18 | Terns Pharmaceuticals, Inc. | Treating liver disorders with an ssao inhibitor |
-
2018
- 2018-08-30 KR KR1020217009346A patent/KR20210052507A/ko not_active Application Discontinuation
- 2018-08-30 JP JP2021536122A patent/JP2022508402A/ja active Pending
- 2018-08-30 WO PCT/CN2018/103349 patent/WO2020042114A1/en unknown
- 2018-08-30 SG SG11202101863YA patent/SG11202101863YA/en unknown
- 2018-08-30 US US17/271,554 patent/US20210244744A1/en active Pending
- 2018-08-30 CA CA3110256A patent/CA3110256A1/en active Pending
- 2018-08-30 CN CN201880097022.0A patent/CN112771026A/zh active Pending
- 2018-08-30 EP EP18931946.0A patent/EP3844156A4/en active Pending
- 2018-08-30 AU AU2018438845A patent/AU2018438845A1/en active Pending
- 2018-08-30 MX MX2021002305A patent/MX2021002305A/es unknown
-
2021
- 2021-02-23 IL IL281052A patent/IL281052A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3844156A1 (en) | 2021-07-07 |
| MX2021002305A (es) | 2021-05-31 |
| JP2022508402A (ja) | 2022-01-19 |
| CA3110256A1 (en) | 2020-03-05 |
| WO2020042114A1 (en) | 2020-03-05 |
| SG11202101863YA (en) | 2021-03-30 |
| EP3844156A4 (en) | 2022-06-08 |
| AU2018438845A1 (en) | 2021-04-01 |
| US20210244744A1 (en) | 2021-08-12 |
| KR20210052507A (ko) | 2021-05-10 |
| CN112771026A (zh) | 2021-05-07 |
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