KR101574630B1 - 허혈성 질환의 완화 및 치료를 위한 약학 조성물 및 그를 전달하기 위한 방법 - Google Patents
허혈성 질환의 완화 및 치료를 위한 약학 조성물 및 그를 전달하기 위한 방법 Download PDFInfo
- Publication number
- KR101574630B1 KR101574630B1 KR1020097001545A KR20097001545A KR101574630B1 KR 101574630 B1 KR101574630 B1 KR 101574630B1 KR 1020097001545 A KR1020097001545 A KR 1020097001545A KR 20097001545 A KR20097001545 A KR 20097001545A KR 101574630 B1 KR101574630 B1 KR 101574630B1
- Authority
- KR
- South Korea
- Prior art keywords
- leu
- glu
- ser
- lys
- arg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83258406P | 2006-07-24 | 2006-07-24 | |
| US60/832,584 | 2006-07-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20090033878A KR20090033878A (ko) | 2009-04-06 |
| KR101574630B1 true KR101574630B1 (ko) | 2015-12-07 |
Family
ID=38997534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097001545A Expired - Fee Related KR101574630B1 (ko) | 2006-07-24 | 2007-07-19 | 허혈성 질환의 완화 및 치료를 위한 약학 조성물 및 그를 전달하기 위한 방법 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7902154B2 (https=) |
| EP (1) | EP2044108A4 (https=) |
| JP (1) | JP2009544688A (https=) |
| KR (1) | KR101574630B1 (https=) |
| CN (1) | CN101490080A (https=) |
| WO (1) | WO2008015580A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250057224A (ko) | 2023-10-19 | 2025-04-29 | 단국대학교 천안캠퍼스 산학협력단 | Pdrn을 이용한 유치줄기세포를 포함하는 세포치료제 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9416383B2 (en) * | 2007-04-27 | 2016-08-16 | University Of North Carolina At Chapel Hill | Method for enhancing catalytic activity of a lipase |
| US7981446B2 (en) * | 2007-11-26 | 2011-07-19 | Forhumantech. Co., Ltd. | Pharmaceutical compositions and methods for delivering nucleic acids into cells |
| CN101612384B (zh) * | 2009-07-23 | 2012-06-20 | 中国人民解放军第二军医大学 | 多肽小分子mlif在制备防治心肌缺血药物中的应用 |
| KR101278221B1 (ko) | 2010-06-01 | 2013-06-24 | 연세대학교 산학협력단 | Ρtd-uqcrb 융합 폴리펩타이드 및 그를 포함하는 허혈성 질환의 예방 및 치료용 약제학적 조성물 |
| JP6262721B2 (ja) | 2012-05-11 | 2018-01-17 | ジェムバックス アンド カエル カンパニー,リミティド | 敗血症の予防用または治療用の組成物 |
| WO2013167298A1 (en) | 2012-05-11 | 2013-11-14 | Kael-Gemvax Co., Ltd. | Anti-inflammatory peptides and composition comprising the same |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| WO2014171792A1 (ko) | 2013-04-19 | 2014-10-23 | 주식회사 카엘젬백스 | 허혈성 손상 치료 및 예방용 조성물 |
| RU2677277C2 (ru) | 2013-06-07 | 2019-01-16 | Джемвакс Энд Каэл Ко., Лтд. | Биологические маркеры, которые могут быть использованы в иммунотерапии рака |
| JP6495899B2 (ja) | 2013-06-21 | 2019-04-03 | ジェムバックス アンド カエル カンパニー,リミティド | ホルモン分泌調節剤、及びそれを含む組成物 |
| KR102359396B1 (ko) | 2013-11-22 | 2022-02-08 | 주식회사 젬백스앤카엘 | 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| KR102314231B1 (ko) | 2013-12-17 | 2021-10-19 | 주식회사 젬백스앤카엘 | 전립선 암 치료용 조성물 |
| WO2015156649A1 (ko) | 2014-04-11 | 2015-10-15 | 주식회사 젬백스앤카엘 | 섬유증 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| JP6466971B2 (ja) * | 2014-04-30 | 2019-02-06 | ジェムバックス アンド カエル カンパニー,リミティド | 臓器、組織又は細胞移植用組成物、キット及び移植方法 |
| WO2015170790A1 (ko) * | 2014-05-09 | 2015-11-12 | 주식회사 카엘젬백스 | 허혈성 손상 치료 및 예방용 조성물 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| KR102636129B1 (ko) | 2015-02-27 | 2024-02-14 | 주식회사 젬백스앤카엘 | 청력 손상 방어용 펩타이드 및 이를 포함하는 조성물 |
| KR102638286B1 (ko) | 2015-07-02 | 2024-02-20 | 주식회사 젬백스앤카엘 | 항바이러스 활성 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
| US10898540B2 (en) | 2016-04-07 | 2021-01-26 | Gem Vax & KAEL Co., Ltd. | Peptide having effects of increasing telomerase activity and extending telomere, and composition containing same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4085297A (en) | 1996-08-23 | 1998-03-06 | Chiron Corporation | Human polyhomeotic 1(hphl) acts as a tumor suppressor |
| US20030104622A1 (en) | 1999-09-01 | 2003-06-05 | Robbins Paul D. | Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses |
| GB0103110D0 (en) * | 2000-08-25 | 2001-03-28 | Aventis Pharma Inc | A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1 |
| KR20030062789A (ko) | 2002-01-19 | 2003-07-28 | 포휴먼텍(주) | 생체분자 전달 펩타이드 sim2-btm 및 이것을포함하는 생명공학제품 |
| KR20030062788A (ko) | 2002-01-19 | 2003-07-28 | 포휴먼텍(주) | 생체분자 전달 펩타이드 mph1-btm 및 이것을포함하는 생명공학제품 |
| KR100591936B1 (ko) | 2002-11-12 | 2006-06-22 | 포휴먼텍(주) | 세포내 dna/rna 전달 방법, 및 이것의 기초 및임상학적 응용 |
| US7166692B2 (en) * | 2003-03-04 | 2007-01-23 | Canbrex Bio Science Walkersville, Inc. | Intracellular delivery of small molecules, proteins, and nucleic acids |
| JP4879020B2 (ja) | 2003-05-01 | 2012-02-15 | コーネル リサーチ ファウンデイション インコーポレイテッド | 細胞に分子を送達する方法及び担体複合体 |
| US7339042B2 (en) * | 2003-06-09 | 2008-03-04 | University Of Florida Research Foundation, Inc. | Gene delivery to tumors |
| ATE478676T1 (de) | 2005-11-04 | 2010-09-15 | Forhumantech Co Ltd | Verfahren zur abgabe von fusionspolypeptid in eine zelle |
| EP2057195A4 (en) | 2006-08-29 | 2010-05-12 | Forhumantech Co Ltd | PHARMACEUTICAL COMPOSITION FOR THE SUPPRESSION OF APOPTOSIS AND METHOD OF ADMINISTERING THE SAME |
-
2007
- 2007-07-19 EP EP07825623A patent/EP2044108A4/en not_active Withdrawn
- 2007-07-19 CN CNA2007800276518A patent/CN101490080A/zh active Pending
- 2007-07-19 WO PCT/IB2007/003404 patent/WO2008015580A2/en not_active Ceased
- 2007-07-19 KR KR1020097001545A patent/KR101574630B1/ko not_active Expired - Fee Related
- 2007-07-19 JP JP2009521380A patent/JP2009544688A/ja active Pending
- 2007-07-24 US US11/878,431 patent/US7902154B2/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| Arch. Biochem. Biophys. 411(2): 174-182(2003. 3. 15.)* |
| Br. J. Cancer 90(1): 230-235(2004. 1. 12.)* |
| J. Steroid Biochem. Mol. Biol. 91(3): 131-138(2004. 7.) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250057224A (ko) | 2023-10-19 | 2025-04-29 | 단국대학교 천안캠퍼스 산학협력단 | Pdrn을 이용한 유치줄기세포를 포함하는 세포치료제 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2044108A4 (en) | 2010-06-30 |
| KR20090033878A (ko) | 2009-04-06 |
| CN101490080A (zh) | 2009-07-22 |
| US7902154B2 (en) | 2011-03-08 |
| EP2044108A2 (en) | 2009-04-08 |
| JP2009544688A (ja) | 2009-12-17 |
| WO2008015580A3 (en) | 2008-06-26 |
| US20090087422A1 (en) | 2009-04-02 |
| WO2008015580A2 (en) | 2008-02-07 |
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