KR101555293B1 - 저점도이면서 고도 응집된 유리체내 주사용 트리암시놀론 아세토니드 현탁액 - Google Patents

저점도이면서 고도 응집된 유리체내 주사용 트리암시놀론 아세토니드 현탁액 Download PDF

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Publication number
KR101555293B1
KR101555293B1 KR1020107022609A KR20107022609A KR101555293B1 KR 101555293 B1 KR101555293 B1 KR 101555293B1 KR 1020107022609 A KR1020107022609 A KR 1020107022609A KR 20107022609 A KR20107022609 A KR 20107022609A KR 101555293 B1 KR101555293 B1 KR 101555293B1
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South Korea
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suspension composition
settling
suspension
chloride
triamcinolone acetonide
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Korean (ko)
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KR20100127267A (ko
Inventor
바그와티 피. 카브라
루마 사카르
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알콘 리서치, 리미티드
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Assigned to 알콘 리서치, 엘엘씨 reassignment 알콘 리서치, 엘엘씨 권리의 전부이전등록 Assignors: 알콘 리서치, 리미티드
Assigned to 알콘 인코포레이티드 reassignment 알콘 인코포레이티드 권리의 전부이전등록 Assignors: 알콘 리서치, 엘엘씨
Assigned to 노파르티스 아게 reassignment 노파르티스 아게 권리의 전부이전등록 Assignors: 알콘 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020107022609A 2008-03-11 2009-03-10 저점도이면서 고도 응집된 유리체내 주사용 트리암시놀론 아세토니드 현탁액 Active KR101555293B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3545908P 2008-03-11 2008-03-11
US61/035,459 2008-03-11

Publications (2)

Publication Number Publication Date
KR20100127267A KR20100127267A (ko) 2010-12-03
KR101555293B1 true KR101555293B1 (ko) 2015-10-06

Family

ID=40548758

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107022609A Active KR101555293B1 (ko) 2008-03-11 2009-03-10 저점도이면서 고도 응집된 유리체내 주사용 트리암시놀론 아세토니드 현탁액

Country Status (21)

Country Link
US (3) US8128960B2 (enExample)
EP (1) EP2262506B1 (enExample)
JP (1) JP5581227B2 (enExample)
KR (1) KR101555293B1 (enExample)
CN (1) CN101959519B (enExample)
AR (1) AR070824A1 (enExample)
AU (1) AU2009223649B2 (enExample)
BR (1) BRPI0909630B8 (enExample)
CA (1) CA2717605C (enExample)
CL (1) CL2009000573A1 (enExample)
DK (1) DK2262506T3 (enExample)
ES (1) ES2471122T3 (enExample)
MX (1) MX2010009974A (enExample)
PL (1) PL2262506T3 (enExample)
PT (1) PT2262506E (enExample)
RU (1) RU2481842C2 (enExample)
SI (1) SI2262506T1 (enExample)
TW (1) TWI468165B (enExample)
UY (1) UY31699A1 (enExample)
WO (1) WO2009114521A1 (enExample)
ZA (1) ZA201005839B (enExample)

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US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
RU2481842C2 (ru) * 2008-03-11 2013-05-20 Алькон Рисерч, Лтд. Низковязкие высокофлокулированные суспензии триамцинолона ацетонида для интравитреальных инъекций
KR20110099044A (ko) * 2008-12-22 2011-09-05 알콘 리서치, 리미티드 후안부에 유효농도의 활성제를 전달하기 위한 국소 안용액 조성물
WO2012051575A2 (en) 2010-10-15 2012-04-19 Iscience Interventional Corporation Device for ocular access
CN102008488B (zh) * 2010-11-24 2012-10-10 广州固志医药科技有限公司 一种曲安奈德眼用制剂及其制备方法
AR090775A1 (es) * 2012-04-23 2014-12-03 Otsuka Pharma Co Ltd Preparado inyectable
AU2013342275B2 (en) * 2012-11-08 2017-11-09 Clearside Biomedical, Inc. Methods and devices for the treatment of ocular diseases in human subjects
SG10201702674PA (en) 2013-05-03 2017-06-29 Clearside Biomedical Inc Apparatus and methods for ocular injection
WO2014197317A1 (en) 2013-06-03 2014-12-11 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
WO2015196085A2 (en) 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US9694145B1 (en) 2016-03-29 2017-07-04 Joseph Onorato Auto-injector systems and method for delivering cyst medication on demand
JP2019514581A (ja) 2016-05-02 2019-06-06 クリアサイド バイオメディカル，インコーポレイテッド 眼の薬物送達のためのシステムおよび方法
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
WO2018204515A1 (en) 2017-05-02 2018-11-08 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
WO2019136512A1 (en) * 2018-01-10 2019-07-18 Eye Co Pty Ltd Medical device and pharmaceutical composition for treatment of an eye disease or condition
USD893715S1 (en) 2018-11-06 2020-08-18 Joseph Onorato Measurement guide for a cyst, lesion or skin disorder
CA3136814A1 (en) * 2019-04-16 2020-10-22 Clearside Biomedical, Inc. Injectable triamcinolone formulations
US10814001B1 (en) 2019-05-06 2020-10-27 Rvl Pharmaceuticals, Inc. Oxymetazoline compositions
CN114010593A (zh) * 2021-11-23 2022-02-08 莱默(北京)药业科技有限公司 一种曲安奈德混悬注射液及制备方法
CN115969784B (zh) * 2022-12-26 2025-10-21 昆明积大制药股份有限公司 曲安奈德注射液的制备方法
WO2025114562A1 (en) * 2023-11-30 2025-06-05 Institut National de la Santé et de la Recherche Médicale Intravitreal spironolactone suspension

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US20050244469A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments

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Also Published As

Publication number Publication date
US8128960B2 (en) 2012-03-06
CN101959519B (zh) 2013-03-20
CN101959519A (zh) 2011-01-26
PT2262506E (pt) 2014-06-24
US20120115829A1 (en) 2012-05-10
KR20100127267A (ko) 2010-12-03
HK1146464A1 (en) 2011-06-10
EP2262506B1 (en) 2014-05-07
BRPI0909630B8 (pt) 2021-05-25
CL2009000573A1 (es) 2010-01-04
US20120116216A1 (en) 2012-05-10
TWI468165B (zh) 2015-01-11
US8211880B2 (en) 2012-07-03
BRPI0909630B1 (pt) 2019-03-26
JP5581227B2 (ja) 2014-08-27
US20090233890A1 (en) 2009-09-17
ZA201005839B (en) 2011-10-26
CA2717605C (en) 2012-05-15
JP2011513492A (ja) 2011-04-28
EP2262506A1 (en) 2010-12-22
CA2717605A1 (en) 2009-09-17
AU2009223649A1 (en) 2009-09-17
WO2009114521A1 (en) 2009-09-17
MX2010009974A (es) 2010-09-30
SI2262506T1 (sl) 2014-07-31
DK2262506T3 (da) 2014-06-10
TW200940071A (en) 2009-10-01
BRPI0909630A2 (pt) 2015-09-22
RU2010141542A (ru) 2012-04-20
PL2262506T3 (pl) 2014-09-30
UY31699A1 (es) 2009-05-29
RU2481842C2 (ru) 2013-05-20
ES2471122T3 (es) 2014-06-25
AU2009223649B2 (en) 2013-08-29
AR070824A1 (es) 2010-05-05

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