KR101338873B1 - The composition of antifreezing and environment friendly disinfectant and method for manufacturing thereof - Google Patents

Abstract

The present invention relates to a freeze-resistant environmentally friendly disinfectant for disinfecting barns, roads, farm vehicles and livestock equipment. More specifically, quaternary ammonium 5-15% by weight, citric anhydride 5-25% by weight, phosphoric acid 5-15% by weight, plant composition extract 10 ~ 40% by weight and 5 to 75% by weight of purified water disinfection It relates to a freeze-resistant environmentally friendly disinfectant composite composition and a method for producing the same, characterized in that the excellent freeze resistance and low toxicity.

Description

The composition of antifreezing and environment friendly disinfectant and method for manufacturing

The present invention is a freeze-resistant eco-friendly disinfectant composite composition for disinfecting livestock farms, roads, farm vehicles and livestock equipment, and a method for manufacturing the same, more specifically, excellent disinfection power and freeze resistance and quickly decomposed in the soil and environmentally friendly It relates to a freeze-resistant eco-friendly disinfectant composite composition and a method of manufacturing the same.

As foot and mouth disease and Avian influenza continue to develop in Korea, the use of livestock disinfectants to kill these pathogens has increased significantly. In particular, due to the nature of foot-and-mouth disease and avian influenza virus mainly occurs during the winter, the livestock disinfectant is frozen during distribution and storage, causing difficulties in cold weather livestock defense. In addition, as the number and usage of livestock disinfectants increases, environmental problems are frequently caused by the toxicity of disinfectants. Therefore, it is required to develop a livestock disinfectant that has excellent freezing resistance to withstand the cold weather and the used disinfectant is decomposed in the soil in a short time.

Currently, domestic livestock disinfectants used for foot-and-mouth disease and algae influenza protection are trichophytes, aldehydes, chlorine, and quaternary ammonium disinfectants.

The trichloride is a livestock disinfectant containing more than 50% by weight of potassium monopersulfate has the advantage of excellent disinfection. However, the trichophytes are highly toxic and odorous, causing side effects such as coughing, tears, and redness of the skin on the handlers and livestock, and polluting the soil or rivers during road disinfection, causing environmental pollution such as inhibiting plant growth and killing fish. There is a problem.

Aldehyde preparation is a livestock disinfectant containing more than 10% by weight of glutaraldehyde and formaldehyde (Formaldehyde) has the advantage of excellent disinfection power and penetration in organic matters while having high toxicity. The Ministry of Environment classifies formaldehyde as a carcinogen and glutaldehyde is classified as toxic.

Chlorine is a livestock disinfectant that contains chlorine dioxide and sodium dichloroisocyanurate, but has a wide range of disinfecting powers. And there is a problem that the sterilization power is significantly reduced when the temperature rises.

Quarterly ammonium compound is a livestock disinfectant containing benzalconium chloride and didecyl dimethyl ammonium chloride, which has low toxicity and is safe for humans and livestock. It has the disadvantage of being insufficient and polluting the environment.

In addition, the above-mentioned livestock disinfectants have a problem of freezing during distribution or storage in the cold weather (less than 10 degrees Celsius). Unlike livestock disinfectants, livestock disinfectants disinfect livestock houses and roads because they disinfect livestock houses and roads, and they are often stored outside, not in the form of drug transport vehicles. It is causing difficulties in prevention.

Therefore, the present invention has been invented to solve the problems of the conventional livestock disinfectant as described above, improves the disinfecting power of quaternary ammonium compound (Quarternary ammonium compound) used as a livestock disinfectant and does not freeze even in cold weather and in the soil It can be quickly disassembled to make it more safe for the environment to solve the conventional problems.

Technical means of the present invention for achieving the above object is a complex composition containing anhydrous citric acid (Anhydrous citric acid), phosphoric acid (Phosphoric acid) and plant extract (Plant extract compound) in a quaternary ammonium compound As the composite composition, the component composition ratio of 5 to 15% by weight of quaternary ammonium, 5 to 25% by weight of citric anhydride, 5 to 15% by weight of phosphoric acid, 10 to 40% by weight of plant mixture extract and 5 to 75% by weight of purified water Characterized in that made.

In addition, as a method for preparing the composite composition, first, 5% by weight of dried and shredded cherry tree ( Prunus sargentii R. ), 10% by weight of seaweed ( Salicornia herbacea L. ) and 1% of sodium edetate (Disidium edetate) % Were put in a liquid stirrer, respectively, and 84% by weight of purified water was added to make the total content 100% by weight. The mixture was allowed to stand for 48 hours, followed by extraction at 70 ° C at 30 rpm for 30 to 60 minutes, followed by cooling to room temperature. The mixture was prepared by filtration with a 100 μm filter, and 30% by weight of purified water was added to a liquid mixer, heated to 40 ° C., and 20% by weight of anhydrous citric acid was added for 30 to 60 minutes at 50 rpm. Dissolve and add 30% by weight of the plant mixture extract prepared above, react at 100 rpm for 60 to 120 minutes, cool to room temperature, and then 10% by weight of bebzalkonium chloride and 10% of phosphoric acid. % Add sequentially and stirred for 15 ~ 30 minutes at a speed 50rpm by Nae formed to manufacture environmentally friendly disinfectant hybrid composition.

The composition of the present invention is a freeze-resistant eco-friendly disinfectant complex composition characterized in that it contains citric anhydride, phosphoric acid, and plant mixture extract as an auxiliary component in quaternary ammonium, so that the heat dissipation is excellent and the freezing resistance is excellent. It can be conveniently and conveniently distributed and stored without facilities, and has very low environmental toxicity, so that it can be sprayed around the barn, roads and vehicles with confidence.

1 is a structural formula showing a chemical structure in which benzalkonium chloride is used according to the present invention.
Figure 2 is a structural formula showing the chemical structure used anhydrous citric acid (Anhydrous citric acid) according to the present invention.
Figure 3 is a structural formula showing the chemical structure used in the phosphoric acid (Phosphoric acid) according to the present invention.

Hereinafter, an embodiment of the present invention will be described in detail with reference to the accompanying drawings, FIG. 1 is benzalkonium chloride according to the present invention, FIG. 2 is anhydroun citric acid, and FIG. 3 is phosphoric acid ( This structural formula shows the chemical structure used for phosphoric acid.

Accordingly, the freeze-resistant eco-friendly disinfectant composite composition according to the present invention is composed of an anhydrous citric acid, phosphoric acid, and a plant mixture extract as a secondary component in the quaternary ammonium, especially in winter, -10 ℃ ℃ cold livestock disinfectant is frozen It is to reduce the damage to the environment by replacing the toxic trichloride and aldehydes by eliminating problems that are difficult to use and improving disinfection.

When describing the respective components of the composite composition, benzalkonium chloride, which is the main active ingredient, may be 5 to 15% by weight based on the total composition. At this time, when benzalkonium chloride is less than 5% by weight, the disinfecting power is insufficient, and in the case of more than 15% by weight, the amount of auxiliary components is too small, so that the effect is insignificant.

Citric anhydride composition of the present invention will preferably use 5 to 25% by weight of the total composition, in the present invention when the amount of citric anhydride is 5% by weight or less, the effect of improving the disinfection power and freezing resistance is less than 25% by weight In the case of long-term storage citric acid is precipitated, there is a problem in stability.

Phosphoric acid used in the present invention is preferably used 5 to 15% by weight of the total composition, in the present invention, when the amount of phosphoric acid is less than 5% by weight, the effect of improving disinfection and freezing resistance is insufficient and the amount of phosphoric acid is 15 When the weight percent or more, some layer separation phenomenon occurred in the product over time, there was a problem in maintaining the content uniformity in the product.

Plant mixture extract of the present invention is preferably 10 to 40% by weight of the total composition, less than 10% by weight is not desirable to improve the freezing resistance and environmental toxicity lower than 40% by weight of other auxiliary components It is not desirable because there is insufficient to improve the problem.

Purified water in the freeze-resistant eco-friendly disinfectant composite composition according to the present invention is to be used as an excipient so that the total weight% of the freeze-resistant eco-friendly disinfectant composite composition is 100% by weight, depending on the total weight of the main active ingredient and auxiliary components.

As such, the manufacturing method of the composition of the freeze-resistant environmentally friendly disinfectant composite composition according to the present invention consists of a plant mixture extract and the final composite composition manufacturing step.

First, the plant mixture extract manufacturing step is dried and finely cut 5% by weight of the wild cherry bark, 10% by weight of seaweed and 1% by weight of sodium edetate in a liquid stirrer and put 84% by weight of purified water so that the total content is 100% by weight. Then, the mixture was allowed to stand for 48 hours and then extracted by stirring at 30 rpm at 70 ° C. for 30 to 120 minutes, cooled to room temperature and filtered through a 100 μm filter to prepare a mixed mixture extract. The extraction time would be 80 minutes.

In the final composite composition manufacturing step, 30% by weight of purified water in a liquid mixer, warmed to 40 ℃, 20% by weight of anhydrous citric acid was dissolved for 30 to 60 minutes at 60rpm speed and put 30% by weight of the plant mixture extract prepared above into 120rpm speed 60 minutes to 120 minutes, and then cooled to room temperature to add 10% by weight of benzalkonium chloride and 10% by weight of phosphoric acid in order to make the total composition 100% by weight, followed by stirring at 60 rpm for 15 minutes to 30 minutes. By preparing the composition, the anhydrous citric acid dissolution time is 40 minutes, the reaction time with the plant mixture extract will be most preferred 90 minutes.

The present invention can be understood in more detail by the following examples and experimental examples, the following examples are intended to illustrate the present invention and are not intended to manufacture the scope of the present invention.

≪ Example 1 >

To prepare a composite composition from the composition as shown in Table 1.

  ingredient Weight / g Benzalkonium chloride 100 mg Purified water 900 mg 1g total

The process for producing a composite composition is as follows.

Purified water was added to the mixer, and then benzalkonium chloride was added and stirred at 60 rpm for 20 minutes to subdivide and package a predetermined amount.

≪ Example 2 >

Next is to prepare a composite composition from the composition shown in Table 2.

ingredient Weight / g Benzalkonium chloride 100 mg Anhydrous citric acid 200 mg Purified water 700 mg 1g total

The process for producing a composite composition is as follows.

Add purified water to the mixer, warm to 40 ° C, add anhydrous citric acid, dissolve at 60 rpm for 40 minutes, cool to room temperature, add benzalkonium chloride, and stir for 20 minutes at 60 rpm to prepare small portions and package.

≪ Example 3 >

To prepare a composite composition as shown in Table 3.

ingredient Weight / g Benzalkonium chloride 100 mg Anhydrous citric acid 200 mg Phosphoric Acid 100 mg Purified water 600 mg 1g total

The process for producing a composite composition is as follows.

Add purified water to the mixer, warm it to 40 ℃, add citric anhydride, dissolve for 40 minutes at 60rpm speed, cool to room temperature, add benzalkonium chloride and phosphoric acid in order, stir for 20 minutes at 60rpm speed, and prepare small portions and package them. It is.

<Example 4>

To prepare a composite composition from the composition as shown in Table 4.

ingredient Weight / g Benzalkonium chloride 100 mg Anhydrous citric acid 200 mg Phosphoric Acid 100 mg Plant Mixture Extract 300 mg Purified water 300 mg 1g total

The process for producing a composite composition is as follows.

Add purified water to the mixer, warm it to 40 ℃, add citric anhydride, dissolve for 40 minutes at 60rpm speed, add plant mixture extract, react for 90 minutes at 120rpm speed, cool to room temperature, add benzalkonium chloride and phosphoric acid in order, and add 60rpm. Stirring at a speed of 20 minutes to subdivided by a certain amount, to produce a packaging.

Composition of freeze-resistant eco-disinfectant complex composition Kinds Freeze-resistant eco-friendly disinfectant complex composition Example 1 Benzalkonium Chloride + Purified Water Example 2 Benzalkonium Chloride + Citric Acid + Purified Water Example 3 Benzalkonium Chloride + Citric Acid + Phosphoric Acid + Purified Water Example 4 Benzalkonium chloride + citric acid + phosphoric acid + plant mixture extract + purified water

<Experimental Example 1>

1. Experimental Method

Examples 1, 2, 3, and 4 were tested according to National Veterinary Research and Quarantine Service Notice No. 2008-14 [Guide to Effectiveness Test of Disinfectants].

2. Experimental results

The disinfecting power of the composition in each embodiment is shown in Table 6 below.

Example Disinfection of Composition Kinds Disinfection Foot and mouth virus Avian Influenza Virus Example 1 no effect Poor effect Example 2 Effect usually Poor effect Example 3 Excellent effect Excellent effect Example 4 Excellent effect Excellent effect

<Experimental Example 2>

1. Experimental Method

Example 1, 2, 3 and 4 composition was tested for freezing resistance. The freeze resistance test of the composition was carried out for 24 hours by quantifying each 500mL in a 500mL beaker at the conditions of minus 1, 3, 5, 10 ℃.

2. Test result

Experimental results of the freezing resistance of the composition is shown in Table 7 below.

Example 1, 2, 3 and 4 environmental toxicity experiments were carried out. The soil was collected from the stream, and each of the example compositions was evenly mixed to have a concentration of 200ppm, and then left for 14 days.

Example Environmental Toxicity of Compositions Kinds Survival number of dogs Survival rate Example 1 42/55 76.4% Example 2 38/55 69.1% Example 3 35/55 63.6% Example 4 51/55 92.7%

As can be seen from the above embodiment, the present invention has excellent disinfection power and excellent freezing resistance, so it can be conveniently and conveniently distributed and stored without extra insulation facilities even in the cold weather in winter, and has very low environmental toxicity. It can be sprayed on.

Claims (5)

Quaternary ammonium 5-15 wt%, citric anhydride 5-25 wt%, phosphoric acid 5-15 wt%, plant mixture extract 10-40 wt% and purified water 5 to 75 wt% Composite composition.
delete The method of claim 1,
The quaternary ammonium is benzalkonium chloride (Benzalkonium chloride) or didecyl dimethyl ammonium chloride (Didecyl dimethyl ammonium chloride) 5 to 15% by weight of a freeze-resistant eco-friendly disinfectant complex composition.
The method of claim 1,
The plant mixture extract is a freeze-resistant eco-friendly disinfectant complex composition characterized in that it comprises a wild cherry tree, seaweed and sodium edetate.
5% by weight of dried bark of cherry tree, 10% by weight of seaweed and 1% by weight of sodium edetate were placed in a liquid stirrer, filled with purified water so that the total content was 100% by weight, and then left to stand for 48 hours. Stirring the mixture at 70 ° C. at 30 rpm for 30 to 60 minutes, extracting the mixture, cooling to room temperature, and filtering the mixture with a 100 μm filter to prepare a plant mixture extract;
Add purified water, warm to 40 ° C, add 20% by weight of citric anhydride, dissolve for 30 to 60 minutes at 60 rpm, add 30% by weight of the plant mixture extract prepared above, react at 120 rpm for 60 minutes to 120 minutes, and cool to room temperature. After adding 10% by weight of benzalkonium chloride, 10% by weight of phosphoric acid and the remaining amount of purified water to make the total composition 100% by weight, stirring at 60 rpm for 15 minutes to 30 minutes to produce a composite composition. Method for producing a disinfectant complex composition.

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