KR20190106166A - The composition of triple salt disinfectant which improved solubility - Google Patents

Abstract

The present invention is to provide a triple salt disinfectant complex composition for livestock with increased solubility, which innovatively reduces the lack of solubility, which has been a problem of the conventional triple salt disinfectant, and which makes the disinfectant powder dissolve well in cold water in winter to eliminate the phenomenon of avoiding the triple salt agent and increase the demand thereof, thereby maximizing the efficiency of disease control.

Description

The composition of triple salt disinfectant which improved solubility}

The present invention is a composite composition for livestock trisitis disinfectants with improved solubility for the prevention of livestock epidemic diseases such as avian influenza, more specifically, disinfectant powders in winter cold water by innovatively improving the poor solubility phenomenon, which is a problem of the existing trichophytes. The present invention relates to a livestock trichloride disinfectant complex composition having a good solubility and improved solubility which improves convenience of use and prevention of pest control.

Recently, Avian influenza is suffering from enormous economic damage due to the continuous outbreak in Korea. Avian influenza is an acute respiratory disease that infects birds, also called bird flu, and is a viral disease with a mortality rate of up to 100%. In particular, avian influenza is a disease that is very important for public health because it can be transmitted from animals to humans. Most countries have established and implemented anti-pollution policies under national responsibility. Avian influenza is a migratory bird carrying the avian influenza virus in Korea during winter, discharging the virus into feces, and the feces of infected migratory birds are contaminated with rodents such as humans, vehicles, and mice, and spread to poultry farms to raise chickens and ducks. It has been reported that horizontal propagation (secondary propagation) occurs through livestock-related vehicles such as feed vehicles.

Therefore, in winter, the Korean government selects a special outbreak period for avian influenza from November to March, and selects a base sterilization site by region, and disinfects the inside and outside of the vehicle by disinfection equipment only for poultry and livestock related vehicles. We carry out.

Currently, domestic livestock disinfectants that are licensed for the prevention of avian influenza are three types of salts, acidic agents, aldehydes, and sodium isocyanate disinfectants.

However, in Korea, avian influenza occurs in winter most of the time, and due to the characteristics of the virus, as the temperature is lowered, the activity of the virus becomes stronger, causing difficulties in the prevention of disinfection using a disinfectant. This is because, in sub-zero conditions, disinfectant particles freeze during disinfectant application or the Brownian movement of the disinfectant particles is reduced, which greatly reduces the disinfection effect.

According to the results of the avian influenza virus disinfection effect test according to the outside temperature recently conducted by the veterinary college, it can be seen that the disinfection effect is significantly lowered to less than half at minus 5 compared to the image 4. In particular, in the case of acid preparations containing quaternary ammonium and organic acid or inorganic acid, the effectiveness of disinfecting avian influenza virus was found to be the greatest decrease in the sub-zero condition. Disinfection effect was found to be small.

Therefore, the guidelines for using disinfectants for the prevention of avian influenza produced by the Ministry of Agriculture, Food and Rural Affairs and the Ministry of Agriculture, Food and Rural Affairs and distributed to poultry and livestock farms nationwide are as follows. In winter, it is recommended to use a triple salt disinfectant.

Triple salt is known as the most widely used disinfectant in the world because it has excellent disinfection power, containing potassium monopersulfate (Potassium monopersulfate). However, since the trichloride is produced in powder due to the nature of the oxidizer-based disinfectant that produces oxygen generated while dissolving in water and exerts disinfecting power, it must be dissolved in water when used.

In particular, in the cold winter season, the disinfectant powder is hardly dissolved in cold water, so the nipple of the high-pressure sprayer is clogged, resulting in evasion from the base disinfectant sterilizer and the livestock farm. In recent years, due to the evasion of avian influenza, some municipalities had administrative measures such as the use of acidic agents, which are easy to use, and exchange for trichophytes. In addition, a study on the use of disinfectant products conducted by a mother university showed that some trichophytic salts in some base disinfectants did not dissolve in water but settled under a disinfection mixture, which caused a great problem in the prevention of avian influenza.

In order to prevent the outbreak of avian influenza, which has become like an annual event in winter, we recommend the use of three salts, an oxidant-based disinfectant that has a relatively low disinfection effect even under sub-zero conditions among various disinfectants. Due to the characteristics of the three salts, the three salts do not dissolve well in cold water, resulting in the avoidance of the three salts in the epidemic officers and farmers, and they do not dissolve well in water.

Patent Application Publication No. 10-1338873 Patent Application Publication No. 10-1323982 Patent Publication No. 10-2012-0102372

Therefore, in order to solve the above problems, the present invention innovatively improves the lack of solubility, which is a problem of the existing three-type disinfectant disinfectant, so that disinfectant powder is well dissolved in cold water in winter, thereby eliminating the need to avoid the three-type disinfectant. It is an object of the present invention to provide a tri-salt disinfectant composite composition for livestock with improved solubility that can be increased and dissolved in water to maximize the efficiency of pest control.

Technical means of the present invention for achieving the above object is triple salt, citric acid, citric acid, sulfamic acid, sodium chloride, sodium olefin sulfonate and A composite composition comprising sodium metaphosphate, wherein the composite composition contains 45 to 65% by weight of trichloride, 15 to 23% by weight of citric acid, 3 to 6% by weight of sulfamic acid, and 1 to 2 of sodium chloride. It is characterized by consisting of 1% by weight, 1 to 3% by weight of sodium olefin sulfonate and 1 to 35% by weight of sodium metaphosphate.

The present invention comprises triple salt, citric acid, sulfamic acid, sodium chloride, sodium chloride, sodium olefin sulfonate and sodium metaphosphate. As a composite composition for livestock trisitis disinfectants with improved solubility, the solubility lacking in solubility, which is a problem of the disinfectants existing, is improved so that the disinfectant powder dissolves well in cold water in winter so as to avoid the repellents There is a very useful effect that can maximize the protection efficiency by dissolving to increase the demand, to dissolve well in water.

Hereinafter, the present invention will be described in more detail.

Sodium trichloride disinfectant composite composition for improved solubility according to the present invention is a disinfectant component, tribasic salt and organic acid agent for improving solubility, citric acid, sulfamic acid, disinfectant enhancer sodium chloride, solubility-improving surfactant sodium olefinsulfonic acid and metaphosphate It is composed of sodium and improves the solubility, which is a problem of the disinfectant of the existing trichophytes, so that the disinfectant powder dissolves well in cold water in winter, causing repellents of the trichophytes and preventing the dissolution in water. Is to solve.

When describing each of the components of the complex composition, the three types of disinfectant components are preferably 45 to 65% by weight based on the total composition. At this time, when the trichloride is less than 45% by weight, the disinfecting power is insufficient, and when more than 65% by weight, it is not preferable because other components cannot be used sufficiently.

Citric acid composition of the present invention is preferably used 15 to 23% by weight of the total composition, when the amount of citric acid in the present invention is less than 15% by weight solubility improvement effect is insufficient and 23% by weight or more is preferably used in excess. I can't.

The sulfamic acid used in the present invention is preferably used in 3 to 6% by weight of the total composition, in the present invention, when the amount of sulfamic is less than 3% by weight solubility improvement effect is insufficient and when the amount is more than 6% by weight Not preferred for use

Sodium chloride in the composition of the present invention is preferably 1 to 2% by weight of the total composition, less than 1% by weight is not preferable because the effect of improving the disinfecting power of trigeminal salts is not preferable, and when more than 2% by weight is not preferable to use excessive.

 Sodium olefin sulfonate used in the present invention is preferably used 1 to 3% by weight of the total composition, when the amount of sodium olefin sulfonate in the present invention is less than 1% by weight solubility improvement effect is insufficient and 3% by weight In this case, it is not preferable to increase the manufacturing cost compared to solubility improvement.

Sodium metaphosphate in the livestock trichloride disinfectant composite composition with improved solubility according to the present invention is the total weight percent of the triple salt disinfectant composite composition according to the combined weight value of the disinfectant component and the solubility improver and the trichloride disinfectant enhancer component It is used as an excipient to be 100% by weight.

The present invention can be understood in more detail by the following comparative examples, examples and experimental examples, the following examples are intended to illustrate the present invention and are not intended to manufacture the scope of the present invention.

Comparative Example 1

To prepare a composite composition from the composition as shown in Table 1.

ingredient weight Trichophytitis 500 g Malic acid 150 g Sulfamic acid 50 g Sodium chloride 15 g Sodium dodecylbenzenesulfonate 165 g Sodium metaphosphate 120 g 1kg total

The process of preparing the composite composition of [Table 1] is as follows.

The ingredients are sequentially added to a powder mixer, followed by mixing for 30 minutes at a speed of 35 rpm to subdivide by a predetermined amount, to prepare the packaging.

To prepare a composite composition from the composition as shown in Table 2.

ingredient weight Trichophytitis 500 g Citric acid 200 g Sodium chloride 15 g Sodium dodecylbenzenesulfonate 165 g Sodium metaphosphate 120 g 1kg total

The process of preparing the composite composition of [Table 2] is as follows.

The ingredients are sequentially added to a powder mixer, followed by mixing for 30 minutes at a speed of 35 rpm to subdivide by a predetermined amount, to prepare the packaging.

To prepare a composite composition from the composition as shown in Table 3.

ingredient weight Trichophytitis 600 g Citric acid 100 g Sulfamic acid 50 g Sodium chloride 15 g Sodium dodecylbenzenesulfonate 165 g Sodium metaphosphate 70 g 1kg total

The process of preparing the composite composition of [Table 3] is as follows.

The ingredients are sequentially added to a powder mixer, followed by mixing for 30 minutes at a speed of 35 rpm to subdivide by a predetermined amount, to prepare the packaging.

To prepare a composite composition from the composition as shown in Table 4.

ingredient weight Trichophytitis 500 g Citric acid 200 g Sodium chloride 15 g Sodium Olefin Sulfonate 15 g Sodium metaphosphate 220 g 1kg total

The process of preparing the composite composition of [Table 4] is as follows.

The ingredients are sequentially added to a powder mixer, followed by mixing for 30 minutes at a speed of 35 rpm to subdivide by a predetermined amount, to prepare the packaging.

To prepare a composite composition from the composition as shown in Table 5.

ingredient weight Trichophytitis 600 g Citric acid 100 g Sulfamic acid 50 g Sodium chloride 15 g Sodium Olefin Sulfonate 15 g Sodium metaphosphate 220 g 1kg total

The process of preparing the composite composition of [Table 5] is as follows.

The ingredients are sequentially added to a powder mixer, followed by mixing for 30 minutes at a speed of 35 rpm to subdivide by a predetermined amount, to prepare the packaging.

To prepare a composite composition from the composition as shown in Table 6.

ingredient weight Trichophytitis 600 g Citric acid 200 g Sulfamic acid 50 g Sodium chloride 15 g Sodium Olefin Sulfonate 15 g Sodium metaphosphate 120 g 1kg total

The process of preparing the composite composition of [Table 6] is as follows.

The ingredients are sequentially added to a powder mixer, followed by mixing for 30 minutes at a speed of 35 rpm to subdivide by a predetermined amount, to prepare the packaging.

Kinds Complex composition for livestock trichloride disinfectant with improved solubility Comparative Example 1 Triple salt (50) + peracid (15) + sulfamic acid (5) + sodium chloride (1.5) + sodium dodecylbenzenesulfonate (16.5) + sodium metaphosphate (12) Example 1 Triple salt (50) + citric acid (20) + sodium chloride (1.5) + sodium dodecylbenzenesulfonate (16.5) + sodium metaphosphate (12) Example 2 Triple salt (60) + citric acid (20) + sulfamic acid (5) + sodium chloride (1.5) + sodium dodecylbenzenesulfonate (16.5) + sodium metaphosphate (7) Example 3 Triple salt (50) + citric acid (20) + sodium chloride (1.5) + sodium olefin sulfonate (1.5) + sodium metaphosphate (12) Example 4 Triple salt (60) + citric acid (10) + sulfamic acid (5) + sodium chloride (1.5) + sodium olefin sulfonate (1.5) + sodium metaphosphate (22) Example 5 Triple salt (60) + citric acid (20) + sulfamic acid (5) + sodium chloride (1.5) + sodium olefin sulfonate (1.5) + sodium metaphosphate (12)

[Table 7] shows the composition of the three-salt disinfectant complex composition for livestock with improved solubility, and the numbers in '()' represent the weight% by weight.

Experimental Example 1

1. Experiment Method

In order to determine the stability of the composite composition of Comparative Example 1 and Examples 1 to 5, each composition was sealed in 1 kg unit in silver foil (PET + PE + AL + PE + LLDPE) and stored at room temperature, shaded for 0 months, After 3 months, 6 months, and 12 months, the content of trichophytitis, a form and disinfection component, was measured.

2. Experimental Results

Both the composite compositions of Comparative Example 1 and each of the examples did not change in appearance, and the content of the disinfectant trichloride was within the range of 90-110%, which is a standard value, and was stable in all examples. The experimental results are shown in Table 8 below.

Kinds Constellation Tertiary salt content (%) At the start 3 months
after 6 months later 12 months later At the start 3 months later 6 months later 12 months later Comparative Example 1 White powder No change No change No change 100.3 100.4 100.3 100.2 Example 1 White powder No change No change No change 100.2 100.4 100.1 100.2 Example 2 White powder No change No change No change 100.5 100.1 100.5 100.3 Example 3 White powder No change No change No change 100.3 100.0 100.4 100.1 Example 4 White powder No change No change No change 100.1 100.3 100.2 100.0 Example 5 White powder No change No change No change 100.3 100.2 100.2 100.3

[Stability of Comparative Example and Example Composition]

Experimental Example 2

1. Experiment Method

In order to measure the solubility of the composite compositions of Comparative Example 1 and Examples 1 to 5, 24 beakers were filled with 1 liter of tap water, respectively, and a water tank equipped with a temperature control device to maintain the tap water temperature of 10, 4, 0, and -5 Six beakers were soaked at each temperature, and the tap water temperature was 10, 4, 0, and -5, respectively. Each beaker accurately weighed 10 g of Comparative Example 1 and Test Examples 1,2,3,4,5 and stirred at 180 RPM for 3 minutes, and then measured solubility after 10 minutes.

2. Experimental Results

Solubility test results for the composite composition of Comparative Example 1 and Examples are shown in Table 9.

Kinds Tap water 100-fold dilution solubility 10 4 0 Minus 5 Comparative Example 1 Great Good Inadequate Bad Example 1 Great Good Inadequate Bad Example 2 Great Good Inadequate Inadequate Example 3 Great Great Good Inadequate Example 4 Great Great Good Good Example 5 Great Great Great Great

[Solubility of Comparative Example and Example Composition]

Experimental Example 3

1. Experiment Method

In order to determine the disinfecting power in the presence of organics of the composite compositions of Comparative Example 1 and Examples 1 to 5 were compared and evaluated using the MIC measurement method. Inoculate 0.2 mL of E. coli ATCC 25922 with 100 mL of Nutrition agar, incubate for 24 hours, and place a test piece of 8 mm diameter and 1.5 mm thickness on the medium, and add yeast extract to each composition. 50% of the diluted 5% organic matter was added to each test piece and put in the incubator and incubated for 24 hours, and then the average diameter of the bacterial growth inhibitory ring was measured.

2. Experimental Results

Results of disinfection of the composite composition of Comparative Example 1 and Examples are shown in Table 10 below.

Kinds Average diameter of germ growth resistant ring (mm) Comparative Example 1 11.5 Example 1 11.7 Example 2 12.1 Example 3 11.6 Example 4 12.4 Example 5 12.8

[Disinfection Power in the Presence of Organics of Comparative and Example Compositions]

As shown in the above experimental examples, the composition for improving livestock trichophytic disinfectant according to the present invention is triple salt, citric acid, citric acid, sulfamic acid, sodium chloride , Formed by mixing a certain ratio of sodium olefin sulfonate and sodium metaphosphate, and disinfectant powder in winter cold water by innovatively improving the solubility lacking problem, which is a problem of the existing disinfectant of conventional trichloride. This dissolution of the three salts to avoid the phenomenon to increase the demand, and to dissolve in water to maximize the efficiency of the quarantine is an invention of high industrial availability.

Claims (2)

Triple salt, citric acid, sulfamic acid, sodium chloride, sodium olefin sulfonate and sodium metaphosphate Livestock trichloride disinfectant complex composition with improved solubility.
The method of claim 1,
The composite composition comprises 45 to 65% by weight of tribasic salt, 15 to 23% by weight of citric acid, 3 to 6% by weight of sulfamic acid, 1 to 2% by weight of sodium chloride, 1 to 3% by weight of olefinsulfonic acid sodium and metaphosphoric acid. Sodium triglyceride disinfectant composite composition with improved solubility, characterized in that consisting of 1 to 35% by weight sodium.