KR101291394B1 - 면역 치료를 위한 새로운 면역원성 에피톱 - Google Patents

면역 치료를 위한 새로운 면역원성 에피톱 Download PDF

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KR101291394B1
KR101291394B1 KR1020107001885A KR20107001885A KR101291394B1 KR 101291394 B1 KR101291394 B1 KR 101291394B1 KR 1020107001885 A KR1020107001885 A KR 1020107001885A KR 20107001885 A KR20107001885 A KR 20107001885A KR 101291394 B1 KR101291394 B1 KR 101291394B1
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cells
peptide
peptides
cancer
cell
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KR20100040889A (ko
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하르프레트 싱
올리버 슈어
클라우디아 트라우트베인
노르베르트 힐프
토니 베인쉔크
스테펜 발터
페터 레반드로브스키
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이매틱스 바이오테크놀로지스 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K—PEPTIDES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
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    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12Y208/02011—Galactosylceramide sulfotransferase (2.8.2.11)

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KR1020107001885A 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱 Expired - Fee Related KR101291394B1 (ko)

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Application Number Priority Date Filing Date Title
EP07014797.0 2007-07-27
EP07014797 2007-07-27
US95316107P 2007-07-31 2007-07-31
US60/953,161 2007-07-31
PCT/EP2008/006153 WO2009015842A2 (en) 2007-07-27 2008-07-25 Novel immunogenic epitopes for immunotherapy

Related Child Applications (1)

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KR1020127005723A Division KR101351195B1 (ko) 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱

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KR20100040889A KR20100040889A (ko) 2010-04-21
KR101291394B1 true KR101291394B1 (ko) 2013-08-07

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KR1020107001885A Expired - Fee Related KR101291394B1 (ko) 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱
KR1020127005723A Expired - Fee Related KR101351195B1 (ko) 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱
KR1020137015148A Expired - Fee Related KR101313915B1 (ko) 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱

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KR1020127005723A Expired - Fee Related KR101351195B1 (ko) 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱
KR1020137015148A Expired - Fee Related KR101313915B1 (ko) 2007-07-27 2008-07-25 면역 치료를 위한 새로운 면역원성 에피톱

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US (5) US8080634B2 (enExample)
EP (7) EP2562184B1 (enExample)
JP (4) JP5484326B2 (enExample)
KR (3) KR101291394B1 (enExample)
CN (3) CN105566450A (enExample)
AU (1) AU2008281014B2 (enExample)
BR (1) BRPI0813626A2 (enExample)
CA (1) CA2694805C (enExample)
EA (1) EA018456B1 (enExample)
ES (7) ES2555282T3 (enExample)
HK (1) HK1223381A1 (enExample)
HU (5) HUE025636T2 (enExample)
MX (1) MX2010001090A (enExample)
NZ (1) NZ582822A (enExample)
PL (7) PL2562184T3 (enExample)
UA (2) UA103751C2 (enExample)
WO (1) WO2009015842A2 (enExample)

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DK1716234T3 (da) * 2004-02-20 2014-01-20 Mologen Ag Substitueret, ikke-kodende nukleinsyremolekyle til terapeutisk og profylaktisk immunstimulering i mennesker og højerestående dyr
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