KR101280786B1 - 멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 - Google Patents

멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 Download PDF

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KR101280786B1
KR101280786B1 KR1020117005275A KR20117005275A KR101280786B1 KR 101280786 B1 KR101280786 B1 KR 101280786B1 KR 1020117005275 A KR1020117005275 A KR 1020117005275A KR 20117005275 A KR20117005275 A KR 20117005275A KR 101280786 B1 KR101280786 B1 KR 101280786B1
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alkyl
compound
compounds
diazocan
chlorophenyl
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KR20110039488A (ko
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마크 데이비드 앤드류
크리스토퍼 고든 바버
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화이자 리미티드
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    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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KR1020117005275A 2008-08-06 2009-07-30 멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 Expired - Fee Related KR101280786B1 (ko)

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US8653008P 2008-08-06 2008-08-06
US61/086,530 2008-08-06
PCT/IB2009/053317 WO2010015972A1 (en) 2008-08-06 2009-07-30 Diazepine and diazocane compounds as mc4 agonists

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KR20110039488A KR20110039488A (ko) 2011-04-18
KR101280786B1 true KR101280786B1 (ko) 2013-07-05

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US (1) US8592403B2 (enExample)
EP (1) EP2326638B9 (enExample)
JP (1) JP5530438B2 (enExample)
KR (1) KR101280786B1 (enExample)
CN (1) CN102171206B (enExample)
AU (1) AU2009278838B2 (enExample)
CA (1) CA2731897C (enExample)
DK (1) DK2326638T5 (enExample)
ES (1) ES2421920T3 (enExample)
IL (1) IL210703A (enExample)
MX (1) MX2011001405A (enExample)
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ZA (1) ZA201100374B (enExample)

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WO2010015972A1 (en) 2010-02-11
US20110136814A1 (en) 2011-06-09
CA2731897C (en) 2013-07-02
US8592403B2 (en) 2013-11-26
ES2421920T3 (es) 2013-09-06
AU2009278838B2 (en) 2013-07-25
CA2731897A1 (en) 2010-02-11
ZA201100374B (en) 2012-03-28
EP2326638A1 (en) 2011-06-01
CN102171206B (zh) 2014-06-25
IL210703A (en) 2015-01-29
AU2009278838A1 (en) 2010-02-11
KR20110039488A (ko) 2011-04-18
CN102171206A (zh) 2011-08-31
DK2326638T3 (da) 2013-08-05
IL210703A0 (en) 2011-03-31
JP5530438B2 (ja) 2014-06-25
MX2011001405A (es) 2011-03-21
HK1158619A1 (en) 2012-07-20
EP2326638B9 (en) 2013-11-13
DK2326638T5 (da) 2014-01-13

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