KR101280786B1 - 멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 - Google Patents

멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 Download PDF

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KR101280786B1
KR101280786B1 KR1020117005275A KR20117005275A KR101280786B1 KR 101280786 B1 KR101280786 B1 KR 101280786B1 KR 1020117005275 A KR1020117005275 A KR 1020117005275A KR 20117005275 A KR20117005275 A KR 20117005275A KR 101280786 B1 KR101280786 B1 KR 101280786B1
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alkyl
compound
compounds
diazocan
chlorophenyl
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KR20110039488A (ko
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마크 데이비드 앤드류
크리스토퍼 고든 바버
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화이자 리미티드
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    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
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KR1020117005275A 2008-08-06 2009-07-30 멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물 Expired - Fee Related KR101280786B1 (ko)

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US8653008P 2008-08-06 2008-08-06
US61/086,530 2008-08-06
PCT/IB2009/053317 WO2010015972A1 (en) 2008-08-06 2009-07-30 Diazepine and diazocane compounds as mc4 agonists

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KR20110039488A KR20110039488A (ko) 2011-04-18
KR101280786B1 true KR101280786B1 (ko) 2013-07-05

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US (1) US8592403B2 (enExample)
EP (1) EP2326638B9 (enExample)
JP (1) JP5530438B2 (enExample)
KR (1) KR101280786B1 (enExample)
CN (1) CN102171206B (enExample)
AU (1) AU2009278838B2 (enExample)
CA (1) CA2731897C (enExample)
DK (1) DK2326638T5 (enExample)
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IL (1) IL210703A (enExample)
MX (1) MX2011001405A (enExample)
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ZA (1) ZA201100374B (enExample)

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EP2326638B1 (en) 2013-06-19
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DK2326638T5 (da) 2014-01-13
CA2731897A1 (en) 2010-02-11
JP5530438B2 (ja) 2014-06-25
US20110136814A1 (en) 2011-06-09
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MX2011001405A (es) 2011-03-21
IL210703A0 (en) 2011-03-31
IL210703A (en) 2015-01-29
EP2326638B9 (en) 2013-11-13
HK1158619A1 (en) 2012-07-20
WO2010015972A1 (en) 2010-02-11
CA2731897C (en) 2013-07-02
AU2009278838B2 (en) 2013-07-25
US8592403B2 (en) 2013-11-26
ES2421920T3 (es) 2013-09-06
KR20110039488A (ko) 2011-04-18
DK2326638T3 (da) 2013-08-05
CN102171206B (zh) 2014-06-25
AU2009278838A1 (en) 2010-02-11

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