KR101143734B1 - 치아우식증 및 치아우식증을 유발하는 박테리아를감소시키기 위한 유산균의 선별과 용도 - Google Patents
치아우식증 및 치아우식증을 유발하는 박테리아를감소시키기 위한 유산균의 선별과 용도 Download PDFInfo
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- KR101143734B1 KR101143734B1 KR1020067025744A KR20067025744A KR101143734B1 KR 101143734 B1 KR101143734 B1 KR 101143734B1 KR 1020067025744 A KR1020067025744 A KR 1020067025744A KR 20067025744 A KR20067025744 A KR 20067025744A KR 101143734 B1 KR101143734 B1 KR 101143734B1
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- Prior art keywords
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- lactobacillus
- reuteri
- strains
- food
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Classifications
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- A—HUMAN NECESSITIES
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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- C—CHEMISTRY; METALLURGY
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2260/00—Particular aspects or types of dairy products
- A23C2260/25—Dairy compositions providing for tooth protective effects, e.g. anticariogenic effects
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A23V2400/00—Lactic or propionic acid bacteria
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- A23V2400/173—Reuteri
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US10/869,185 US7517681B2 (en) | 2003-01-29 | 2004-06-14 | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries |
| US10/869,185 | 2004-06-14 | ||
| PCT/SE2005/000805 WO2005121312A1 (en) | 2004-06-14 | 2005-05-30 | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020117017996A Division KR101261172B1 (ko) | 2004-06-14 | 2005-05-30 | 치아우식증 및 치아우식증을 유발하는 박테리아를 감소시키기 위한 유산균의 선별과 용도 |
Publications (2)
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| KR20070030819A KR20070030819A (ko) | 2007-03-16 |
| KR101143734B1 true KR101143734B1 (ko) | 2012-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1020117017996A KR101261172B1 (ko) | 2004-06-14 | 2005-05-30 | 치아우식증 및 치아우식증을 유발하는 박테리아를 감소시키기 위한 유산균의 선별과 용도 |
| KR1020067025744A KR101143734B1 (ko) | 2004-06-14 | 2005-05-30 | 치아우식증 및 치아우식증을 유발하는 박테리아를감소시키기 위한 유산균의 선별과 용도 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1020117017996A KR101261172B1 (ko) | 2004-06-14 | 2005-05-30 | 치아우식증 및 치아우식증을 유발하는 박테리아를 감소시키기 위한 유산균의 선별과 용도 |
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| US (1) | US7517681B2 (zh) |
| EP (1) | EP1765975A1 (zh) |
| JP (2) | JP5566007B2 (zh) |
| KR (2) | KR101261172B1 (zh) |
| CN (1) | CN1981028A (zh) |
| AU (1) | AU2005252605B2 (zh) |
| BR (1) | BRPI0511372B1 (zh) |
| CA (1) | CA2569141C (zh) |
| IN (2) | IN244537B (zh) |
| MX (1) | MX287430B (zh) |
| NZ (1) | NZ552585A (zh) |
| SG (1) | SG128035A1 (zh) |
| WO (1) | WO2005121312A1 (zh) |
| ZA (1) | ZA200700210B (zh) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7517681B2 (en) * | 2003-01-29 | 2009-04-14 | Biogaia Ab | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries |
| CN101273737B (zh) * | 2007-03-28 | 2011-08-24 | 哈尔滨正方科技有限公司 | 一种在常温下保持高活菌数的发酵乳饮料的制备方法 |
| EP2318511B1 (en) * | 2008-08-28 | 2017-08-02 | Chr. Hansen A/S | Bacterial composition |
| PT2361081T (pt) * | 2008-10-14 | 2016-09-05 | Mcneil Ab | Forma de dosagem intra-oral multiporção e seu uso |
| JP5645192B2 (ja) | 2009-07-16 | 2014-12-24 | 国立大学法人広島大学 | 口腔内疾患の予防、改善又は治療剤 |
| US20110293710A1 (en) * | 2010-02-02 | 2011-12-01 | Delphine Saulnier | Immunomodulatory properties of lactobacillus strains |
| IT1398648B1 (it) * | 2010-03-09 | 2013-03-08 | Probiotical Spa | Prodotto alimentare comprendente batteri probiotici rivestiti con un rivestimento di origine vegetale. |
| JP2012092094A (ja) * | 2010-09-30 | 2012-05-17 | Wakamoto Pharmaceutical Co Ltd | 油脂中に乳酸菌を含有する口腔用組成物 |
| GB201206599D0 (en) | 2012-04-13 | 2012-05-30 | Univ Manchester | Probiotic bacteria |
| NZ712617A (en) * | 2013-04-17 | 2020-02-28 | Suntory Holdings Ltd | Bacterium belonging to genus lactobacillus |
| JP5891337B2 (ja) | 2013-04-17 | 2016-03-22 | サントリーホールディングス株式会社 | ラクトバチルス属菌含有組成物 |
| CN103478390B (zh) * | 2013-08-13 | 2015-04-15 | 华侨大学 | 一种预防和辅助治疗牙周炎的口香糖的制备方法 |
| KR102095339B1 (ko) * | 2017-06-01 | 2020-05-27 | 한국생명공학연구원 | 신규한 락토바실러스 류테리 균주 및 이를 유효성분으로 포함하는 치주질환 예방 또는 치료용 조성물 |
| KR101966772B1 (ko) * | 2017-07-11 | 2019-04-09 | 주식회사 다케어 | 락토바실러스 루테리 cs 132(kctc 11452bp) 또는 이의 배양물을 포함하는 구강병원균 억제조성물 |
| KR102001074B1 (ko) * | 2018-12-07 | 2019-07-18 | 주식회사 메디오젠 | 충치 억제 활성을 갖는 유산균 조성물 |
| KR102210092B1 (ko) * | 2019-07-09 | 2021-02-01 | 주식회사 메디오젠 | 충치 억제 활성을 갖는 락토바실러스 루테리 mg505 를 포함하는 조성물 |
| KR102230517B1 (ko) * | 2019-07-09 | 2021-03-22 | 주식회사 메디오젠 | 충치 억제 활성을 갖는 락토바실러스 살리바리우스를 포함하는 조성물 |
| IT202100000176A1 (it) * | 2021-01-07 | 2022-07-07 | Metis Healthcare S R L | Preparazioni orali a base di carnosina ad attività antivirale |
| CN113652340A (zh) * | 2021-08-24 | 2021-11-16 | 江苏江大源生态生物科技股份有限公司 | 一种益生菌制剂、菌种筛选装置及筛选方法 |
| EP4417684A1 (en) | 2021-10-11 | 2024-08-21 | Ajinomoto Co., Inc. | Bacterium modified to express heterologous tat protein |
| JP2023172607A (ja) * | 2022-05-24 | 2023-12-06 | 株式会社アデランス | 乳酸菌含有ガム |
| KR102637772B1 (ko) | 2023-09-21 | 2024-02-20 | 주식회사 큐옴바이오 | 위건강과 구강질환 관련 미생물 및 병원성 미생물에 대한 항균활성을 갖는 산삼 유래 락토바실러스 플란타럼 wg.q7 균주 및 이의 용도 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003299480A (ja) | 2002-04-09 | 2003-10-21 | Hiroki Futagawa | 虫歯予防用細菌、虫歯予防用食品、虫歯予防用口腔洗浄剤及びヨーグルトの製造方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH637297A5 (fr) * | 1978-12-05 | 1983-07-29 | Nestle Sa | Microbille comprenant un microorganisme et son procede de fabrication. |
| EP0154549B1 (en) * | 1984-03-09 | 1990-12-27 | Kabushiki Kaisya Advance | Anticariogenic or antiperiodontitic agent |
| US5413960A (en) * | 1987-05-01 | 1995-05-09 | Biogaia Ab | Antibiotic reuterin |
| FR2672494A1 (fr) | 1991-02-13 | 1992-08-14 | Madinier Isabelle | Ferments prophylactiques favorisant la prevention de la carie dentaire. |
| ES2199305T3 (es) * | 1995-12-21 | 2004-02-16 | Biogaia Ab | Uso de lactobacillus reuteri para inhibir criptosporidiosis en mamiferos. |
| US5837238A (en) * | 1996-06-05 | 1998-11-17 | Biogaia Biologics Ab | Treatment of diarrhea |
| US5800813A (en) * | 1996-11-12 | 1998-09-01 | Biogaia Biologics Ab | Treatment of cryptosporidium infections |
| KR19990024297A (ko) * | 1997-08-07 | 1999-04-06 | 오종석 | 인체 구강내 치태형성을 억제하는 신규한 유산균 |
| US6100388A (en) * | 1998-03-16 | 2000-08-08 | Biogaia Biologies Ab | Lactobacilli harboring aggregation gene as a vaccine delivery vehicle |
| US6461607B1 (en) * | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| GB9920578D0 (en) | 1999-08-31 | 1999-11-03 | Nestle Sa | Composition for maintenance of bone or dental health or treatment of bone or dental disorders |
| JP3824312B2 (ja) * | 2000-05-02 | 2006-09-20 | ビオフェルミン製薬株式会社 | 噴霧乾燥による菌体乾燥物 |
| JP3363438B2 (ja) * | 2000-05-02 | 2003-01-08 | ビオフェルミン製薬株式会社 | 噴霧乾燥による菌体乾燥物 |
| US6872565B2 (en) * | 2003-01-29 | 2005-03-29 | Biogaia Ab | Product containing Lactobacillus reuteri strain ATTC PTA-4965 or PTA-4964 for inhibiting bacteria causing dental caries |
| US7517681B2 (en) * | 2003-01-29 | 2009-04-14 | Biogaia Ab | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003299480A (ja) | 2002-04-09 | 2003-10-21 | Hiroki Futagawa | 虫歯予防用細菌、虫歯予防用食品、虫歯予防用口腔洗浄剤及びヨーグルトの製造方法 |
Also Published As
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| JP2008502360A (ja) | 2008-01-31 |
| KR101261172B1 (ko) | 2013-05-09 |
| MX287430B (es) | 2011-06-13 |
| CN1981028A (zh) | 2007-06-13 |
| EP1765975A1 (en) | 2007-03-28 |
| JP2012130358A (ja) | 2012-07-12 |
| JP5566007B2 (ja) | 2014-08-06 |
| CA2569141A1 (en) | 2005-12-22 |
| SG128035A1 (en) | 2007-01-30 |
| CA2569141C (en) | 2012-05-29 |
| ZA200700210B (en) | 2008-05-28 |
| BRPI0511372B1 (pt) | 2020-09-15 |
| BRPI0511372A (pt) | 2007-12-04 |
| WO2005121312A1 (en) | 2005-12-22 |
| KR20070030819A (ko) | 2007-03-16 |
| IN2006DE07653A (en) | 2007-08-17 |
| KR20110093951A (ko) | 2011-08-18 |
| US20050002874A1 (en) | 2005-01-06 |
| IN244537B (zh) | 2010-12-17 |
| US7517681B2 (en) | 2009-04-14 |
| NZ552585A (en) | 2009-08-28 |
| MXPA06014516A (es) | 2007-03-12 |
| AU2005252605A1 (en) | 2005-12-22 |
| AU2005252605B2 (en) | 2010-08-12 |
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