KR101014586B1 - 하나 이상의 레티노이드 및 벤조일 퍼옥시드를 포함하는 겔 - Google Patents

하나 이상의 레티노이드 및 벤조일 퍼옥시드를 포함하는 겔 Download PDF

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Publication number
KR101014586B1
KR101014586B1 KR1020047008461A KR20047008461A KR101014586B1 KR 101014586 B1 KR101014586 B1 KR 101014586B1 KR 1020047008461 A KR1020047008461 A KR 1020047008461A KR 20047008461 A KR20047008461 A KR 20047008461A KR 101014586 B1 KR101014586 B1 KR 101014586B1
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KR
South Korea
Prior art keywords
composition
benzoyl peroxide
weight
water
acne
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1020047008461A
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English (en)
Korean (ko)
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KR20050016290A (ko
Inventor
오르소니상드린
윌콕스나딸리
Original Assignee
갈데르마 리써어치 앤드 디벨로프먼트
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Application filed by 갈데르마 리써어치 앤드 디벨로프먼트 filed Critical 갈데르마 리써어치 앤드 디벨로프먼트
Publication of KR20050016290A publication Critical patent/KR20050016290A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020047008461A 2001-12-21 2002-12-09 하나 이상의 레티노이드 및 벤조일 퍼옥시드를 포함하는 겔 Expired - Lifetime KR101014586B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0116747A FR2833841B1 (fr) 2001-12-21 2001-12-21 Gel comprenant au moins un retinoide et du peroxyde de benzoyle
FR0116747 2001-12-21
PCT/FR2002/004233 WO2003055472A1 (fr) 2001-12-21 2002-12-09 Gel comprenant au moins un retinoide et du peroxyde de benzoyle

Publications (2)

Publication Number Publication Date
KR20050016290A KR20050016290A (ko) 2005-02-21
KR101014586B1 true KR101014586B1 (ko) 2011-02-16

Family

ID=8870899

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047008461A Expired - Lifetime KR101014586B1 (ko) 2001-12-21 2002-12-09 하나 이상의 레티노이드 및 벤조일 퍼옥시드를 포함하는 겔

Country Status (22)

Country Link
EP (1) EP1458369B1 (https=)
JP (2) JP4889922B2 (https=)
KR (1) KR101014586B1 (https=)
CN (1) CN1329025C (https=)
AR (1) AR038026A1 (https=)
AT (1) ATE347354T1 (https=)
AU (2) AU2002364437B2 (https=)
BR (1) BRPI0214264B8 (https=)
CA (1) CA2466321C (https=)
CY (1) CY1107583T1 (https=)
DE (2) DE60216634T2 (https=)
DK (1) DK1458369T3 (https=)
ES (1) ES2275948T3 (https=)
FR (2) FR2833841B1 (https=)
HU (1) HU230439B1 (https=)
MX (1) MXPA04005918A (https=)
PL (1) PL220838B1 (https=)
PT (1) PT1458369E (https=)
RU (1) RU2320327C2 (https=)
SI (1) SI1458369T1 (https=)
WO (1) WO2003055472A1 (https=)
ZA (1) ZA200403759B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018080284A1 (ko) * 2016-10-31 2018-05-03 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물

Families Citing this family (46)

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FR2833841B1 (fr) * 2001-12-21 2005-07-22 Galderma Res & Dev Gel comprenant au moins un retinoide et du peroxyde de benzoyle
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
EP1813312A3 (en) * 2002-09-05 2010-03-24 Galderma Research & Development Depigmenting composition for the skin comprising adapalene and at least one depigmenting agent
US7544674B2 (en) 2002-10-25 2009-06-09 Galderma S.A. Topical skin care composition
MX2007005449A (es) * 2004-11-09 2007-12-07 Imaginative Res Associates Inc Soluciones de retinoides y formulaciones preparadas a partir de las mismas.
EA015815B1 (ru) 2005-08-02 2011-12-30 Сол-Джел Текнолоджиз Лтд. Покрытие из оксида металла для водонерастворимых ингредиентов
FR2889662B1 (fr) * 2005-08-11 2011-01-14 Galderma Res & Dev Emulsion de type huile-dans-eau pour application topique en dermatologie
WO2007052157A2 (en) * 2005-09-02 2007-05-10 Galderma Research & Development Depigmenting composition for the skin, comprising adapalene, at least one depigmenting agent and at least one anti-inflammatory agent
FR2890314B1 (fr) * 2005-09-02 2009-03-20 Galderma Res & Dev Compositiondepigmentante de la peau comprenant de l'adapalene au moins un agent depigmentant et au moins un agent anti-inflammatoire
ES2560540T3 (es) * 2006-03-31 2016-02-19 Stiefel Research Australia Pty Ltd Gel en suspensión espumable
FR2901139B1 (fr) * 2006-05-17 2009-03-20 Galderma Res & Dev S N C Snc Compositions comprenant au moins un derive de l'acide naphtoique et du peroxyde de benzoyle, leurs procedes de preparation, et leurs utilisations
EP3184108A1 (en) * 2006-07-13 2017-06-28 Galderma Research & Development Composition comprising a retinoid and benzoyl peroxide
FR2903604B1 (fr) * 2006-07-13 2008-09-05 Galderma Res & Dev S N C Snc Composition comprenant un retinoide et du peroxyde de benzoyle
FR2903603B1 (fr) 2006-07-13 2009-03-20 Galderma Res & Dev S N C Snc Combinaison d'adapalene et de peroxyde de benzole dans le traitement de l'acne
US8080537B2 (en) 2006-07-13 2011-12-20 Galderma Research & Development Combinations of adapalene and benzoyl peroxide for treating acne lesions
FR2909000B1 (fr) * 2006-11-28 2009-02-06 Galderma Res & Dev S N C Snc Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations.
FR2910321B1 (fr) * 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) * 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
JP2011510907A (ja) * 2007-01-30 2011-04-07 ガルデルマ・リサーチ・アンド・デヴェロップメント 尋常性ざ瘡の長期間の処置のためのアダパレンおよび過酸化ベンゾイルの使用
AU2008211554B2 (en) 2007-02-01 2013-12-19 Sol-Gel Technologies Ltd. Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
US20100047357A1 (en) * 2007-02-01 2010-02-25 Sol-Gel Technologies Ltd. Compositions for topical application comprising a peroxide and retinoid
EP1967180A1 (de) * 2007-03-06 2008-09-10 Almirall Hermal GmbH Topische Zusammensetzung enthaltend einen Retinoid-Rezeptor-Agonist
FR2916975B1 (fr) * 2007-06-11 2009-09-04 Galderma Res & Dev Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations
FR2916966B1 (fr) * 2007-06-11 2011-01-14 Galderma Res & Dev Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations
EP2065032A1 (en) * 2007-11-27 2009-06-03 Galderma Research & Development A method for producing adapalene gels
CN101969923A (zh) * 2007-11-30 2011-02-09 盖尔德马研究及发展公司 含有至少一种萘甲酸衍生物、过氧化苯甲酰和至少一种成膜剂的组合物、它们的制备方法及其用途
CN102056481A (zh) 2008-06-05 2011-05-11 陶氏制药科学公司 包含低浓度的在水和水混溶性有机溶剂中的悬浮液形式的过氧苯甲酰的局部药物制剂
SI2352488T1 (sl) 2008-11-07 2017-07-31 Klox Technologies Inc. Oksidativni fotoaktiviran sestavek za pomlajevanje kože, ki vsebuje hialuronsko kislino, glukozamin ali alantoin
CN102686208A (zh) * 2009-10-07 2012-09-19 塔格拉生物科技有限公司 包含过氧化苯甲酰的微胶囊和包含所述微胶囊的局部用组合物
JP5784619B2 (ja) * 2009-10-21 2015-09-24 ドウ ファーマシューティカル サイエンシーズ、インク． 過酸化ベンゾイルを含む粉末を湿潤させるための方法
JP2013518920A (ja) 2010-02-09 2013-05-23 ガルデルマ・リサーチ・アンド・デヴェロップメント 非白人系人種における炎症後色素沈着の減少と共にざ瘡の処置を目的とする、アダパレンと過酸化ベンゾイルとの組合せを含む皮膚科学的組成物
FR2969491B1 (fr) * 2010-12-23 2013-07-12 Galderma Res & Dev Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant une combinaison d'adapalene et de bpo
FR2969492B1 (fr) * 2010-12-23 2013-07-05 Galderma Res & Dev Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant de l'adapalene
US8563535B2 (en) 2011-03-29 2013-10-22 Kamal Mehta Combination composition comprising benzoyl peroxide and adapalene
CA2870690A1 (en) 2012-05-25 2013-11-28 Galderma Research & Development Treatment of preadolescent moderate acne vulgaris
PL2919747T3 (pl) * 2012-11-13 2019-03-29 Galderma S.A. Kompozycja żelu do mycia z bpo
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
EP3082785A1 (en) 2013-12-19 2016-10-26 Galderma Research & Development Therapy regimen for treating severe acne related diseases
BR112016022743A2 (pt) 2014-04-01 2017-08-15 Galderma Res & Dev Método para tratar e/ou evitar pelo menos uma cicatriz de acne, uso de uma combinação fixa de adapaleno e peróxido de benzoíla e composição
SMT202000705T1 (it) 2014-07-25 2021-01-05 Galderma Res & Dev Combinazione di adapalene e benzoilperossido per il trattamento di acne grave
WO2017029665A1 (en) * 2015-08-20 2017-02-23 Sol-Gel Technologies Ltd. Compositions for topical application comprising benzoyl peroxide and adapalene
CN106729722B (zh) * 2016-11-21 2020-05-12 成都山信药业有限公司 一种制备稳定复方制剂的方法及复方制剂
CA3069359C (en) 2017-07-12 2023-01-10 Sol-Gel Technologies Ltd. Compositions comprising encapsulated tretinoin
PH12021552514A1 (en) * 2019-04-04 2022-10-03 Galderma Hoding Sa Isopropylcarbonate benzoyl peroxide compositions and methods of use
WO2023112664A1 (ja) * 2021-12-14 2023-06-22 ロート製薬株式会社 過酸化ベンゾイルを含有する医薬外用組成物
EP4493179A4 (en) * 2022-03-14 2026-04-22 Blue Hill Tech Llc LONG-SHELF BENZOYL PEROXIDE FORMULATIONS AND THEIR PRODUCTION PROCESSES

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GB1594314A (en) * 1977-01-26 1981-07-30 Grupper C Medicine for the treatment of acne
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation

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LU85849A1 (fr) * 1985-04-11 1986-11-05 Cird Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques
FR2628319B1 (fr) * 1988-03-09 1990-12-07 Oreal Compositions pharmaceutiques et cosmetiques a base de peroxyde de benzoyle et de sels d'ammonium quaternaires
DK0608353T3 (da) * 1991-10-16 1996-07-01 Richardson Vicks Inc Vandig, kosmetisk gel med lav pH-værdi og indeholdende ikke-ioniske polyacrylamidderivater
US5470884A (en) * 1994-05-19 1995-11-28 Procter & Gamble Anti-acne compositions
FR2785284B1 (fr) * 1998-11-02 2000-12-01 Galderma Res & Dev Analogues de la vitamine d
FR2787322B1 (fr) * 1998-12-18 2002-10-18 Galderma Res & Dev Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie
JP2003525873A (ja) * 1999-12-20 2003-09-02 ヘンケル・コマンディットゲゼルシャフト・アウフ・アクチエン タブレット化増粘系
FR2833841B1 (fr) * 2001-12-21 2005-07-22 Galderma Res & Dev Gel comprenant au moins un retinoide et du peroxyde de benzoyle

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
GB1594314A (en) * 1977-01-26 1981-07-30 Grupper C Medicine for the treatment of acne
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018080284A1 (ko) * 2016-10-31 2018-05-03 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물

Also Published As

Publication number Publication date
JP2011037904A (ja) 2011-02-24
JP5478468B2 (ja) 2014-04-23
FR08C0024I2 (https=) 2009-11-20
EP1458369A1 (fr) 2004-09-22
HUP0500006A2 (en) 2006-08-28
FR08C0024I1 (https=) 2008-07-18
RU2320327C2 (ru) 2008-03-27
DE60216634T2 (de) 2007-09-27
CY1107583T1 (el) 2013-03-13
BRPI0214264B8 (pt) 2021-05-25
SI1458369T1 (sl) 2007-04-30
BRPI0214264B1 (pt) 2017-04-18
RU2004122429A (ru) 2005-03-20
AU2002364437B2 (en) 2008-08-21
CN1607946A (zh) 2005-04-20
AU2008246274A1 (en) 2008-12-11
BR0214264A (pt) 2004-09-21
ES2275948T3 (es) 2007-06-16
CA2466321C (fr) 2011-11-08
FR2833841B1 (fr) 2005-07-22
CA2466321A1 (fr) 2003-07-10
DK1458369T3 (da) 2007-04-10
AU2008246274B2 (en) 2011-05-19
JP4889922B2 (ja) 2012-03-07
KR20050016290A (ko) 2005-02-21
EP1458369B1 (fr) 2006-12-06
ATE347354T1 (de) 2006-12-15
HUP0500006A3 (en) 2009-09-28
ZA200403759B (en) 2005-11-30
AU2002364437A1 (en) 2003-07-15
PT1458369E (pt) 2007-03-30
WO2003055472A1 (fr) 2003-07-10
PL372270A1 (en) 2005-07-11
FR2833841A1 (fr) 2003-06-27
DE122008000041I1 (de) 2008-11-20
PL220838B1 (pl) 2016-01-29
DE60216634D1 (de) 2007-01-18
MXPA04005918A (es) 2004-11-01
CN1329025C (zh) 2007-08-01
HU230439B1 (hu) 2016-06-28
JP2005513146A (ja) 2005-05-12
AR038026A1 (es) 2004-12-22

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