KR100965205B1 - 하부요로 폐색 질환에 따른 축뇨장해의 예방 및/또는치료제 - Google Patents
하부요로 폐색 질환에 따른 축뇨장해의 예방 및/또는치료제 Download PDFInfo
- Publication number
- KR100965205B1 KR100965205B1 KR1020077008737A KR20077008737A KR100965205B1 KR 100965205 B1 KR100965205 B1 KR 100965205B1 KR 1020077008737 A KR1020077008737 A KR 1020077008737A KR 20077008737 A KR20077008737 A KR 20077008737A KR 100965205 B1 KR100965205 B1 KR 100965205B1
- Authority
- KR
- South Korea
- Prior art keywords
- group
- urinary tract
- therapeutic agent
- prophylactic
- lower urinary
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Description
Claims (6)
- 실로도신 또는 그 약리학적으로 허용되는 염을 1일 투여량으로서 2~16mg 함유하고, 축뇨장해를 나타내는 환자에 투여하는 것을 특징으로 하는, 하부요로 폐색 질환에 따른 축뇨장해의 예방 또는 치료제.
- 제 1 항에 있어서, 하부요로 폐색 질환이 전립선 비대증인 것을 특징으로 하는 하부요로 폐색 질환에 따른 축뇨장해의 예방 또는 치료제.
- 제 1 항 또는 제 2 항에 있어서, 축뇨장해를 나타내는 환자가, 국제 전립선 증상 스코어에서 투여 전에 있어서의 「2시간 이내의 배뇨」 및 「요의절박감」의 합계 스코어가 6 이상인 환자인 것을 특징으로 하는 하부요로 폐색 질환에 따른 축뇨장해의 예방 또는 치료제.
- 제 1 항 또는 제 2 항에 있어서, 실로도신 또는 그 약리학적으로 허용되는 염의 1일 투여량이 4∼8mg인 것을 특징으로 하는 하부요로 폐색 질환에 따른 축뇨장해의 예방 또는 치료제.
- 제 1 항 또는 제 2 항에 있어서, 축뇨장해에 사용할 수 있는 다른 약제를 더 함유하는 것을 특징으로 하는 하부요로 폐색 질환에 따른 축뇨장해의 예방 또는 치료제.
- 삭제
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JPJP-P-2004-00292731 | 2004-10-05 | ||
JP2004292731 | 2004-10-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20070059151A KR20070059151A (ko) | 2007-06-11 |
KR100965205B1 true KR100965205B1 (ko) | 2010-06-24 |
Family
ID=36142684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020077008737A KR100965205B1 (ko) | 2004-10-05 | 2005-10-04 | 하부요로 폐색 질환에 따른 축뇨장해의 예방 및/또는치료제 |
Country Status (8)
Country | Link |
---|---|
US (2) | US20090227651A1 (ko) |
EP (1) | EP1800677A4 (ko) |
JP (1) | JPWO2006038611A1 (ko) |
KR (1) | KR100965205B1 (ko) |
CN (1) | CN101027052A (ko) |
CA (1) | CA2582339C (ko) |
TW (1) | TW200621234A (ko) |
WO (1) | WO2006038611A1 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009067737A (ja) * | 2007-09-14 | 2009-04-02 | Kitasato Institute | 放射線治療後下部尿路症状の治療及び/または予防剤 |
JP6482243B2 (ja) * | 2013-11-12 | 2019-03-13 | キッセイ薬品工業株式会社 | 末梢神経障害における感覚神経障害の予防または治療用医薬組成物 |
US9460365B1 (en) * | 2015-03-24 | 2016-10-04 | Intel Corporation | Clustered palette compression |
CN104984130A (zh) * | 2015-07-16 | 2015-10-21 | 石学乾 | 一种治疗尿路梗阻的中药制剂 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000247998A (ja) | 1999-02-26 | 2000-09-12 | Kissei Pharmaceut Co Ltd | α1Aアドレナリン受容体の変異体、当該変異体を用いた測定方法及び前立腺肥大に伴う排尿困難症治療剤 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU9095998A (en) * | 1997-09-22 | 1999-04-12 | Kissei Pharmaceutical Co. Ltd. | Remedies for dysuria resulting from prostatic hypertrophy |
JP2001288115A (ja) * | 2001-02-07 | 2001-10-16 | Yamanouchi Pharmaceut Co Ltd | 下部尿路症治療剤 |
UA78854C2 (en) * | 2002-09-06 | 2007-04-25 | Kissei Pharmaceutical | Crystal for an oral solid drug and oral solid drug for dysuria treatment containing the same |
MXPA05006513A (es) * | 2002-12-16 | 2005-09-08 | Kissei Pharmaceutical | Farmaco solido para uso oral. |
CH698144B1 (fr) * | 2003-09-24 | 2009-05-29 | Bioxell Spa | Analogue de la vitamine D3 |
WO2005085195A1 (ja) * | 2004-03-05 | 2005-09-15 | Kissei Pharmaceutical Co., Ltd. | 神経障害に伴う過活動膀胱の予防または治療用医薬組成物 |
JP4808613B2 (ja) * | 2004-03-24 | 2011-11-02 | キッセイ薬品工業株式会社 | 頻尿または尿失禁の予防または治療用医薬 |
-
2005
- 2005-10-04 KR KR1020077008737A patent/KR100965205B1/ko active IP Right Grant
- 2005-10-04 CN CNA2005800324847A patent/CN101027052A/zh active Pending
- 2005-10-04 EP EP05790516A patent/EP1800677A4/en not_active Withdrawn
- 2005-10-04 WO PCT/JP2005/018334 patent/WO2006038611A1/ja active Application Filing
- 2005-10-04 JP JP2006539293A patent/JPWO2006038611A1/ja active Pending
- 2005-10-04 US US11/576,678 patent/US20090227651A1/en not_active Abandoned
- 2005-10-04 CA CA2582339A patent/CA2582339C/en active Active
- 2005-10-05 TW TW094134755A patent/TW200621234A/zh unknown
-
2010
- 2010-02-01 US US12/697,821 patent/US20100137399A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000247998A (ja) | 1999-02-26 | 2000-09-12 | Kissei Pharmaceut Co Ltd | α1Aアドレナリン受容体の変異体、当該変異体を用いた測定方法及び前立腺肥大に伴う排尿困難症治療剤 |
Also Published As
Publication number | Publication date |
---|---|
KR20070059151A (ko) | 2007-06-11 |
TW200621234A (en) | 2006-07-01 |
EP1800677A1 (en) | 2007-06-27 |
EP1800677A4 (en) | 2008-04-02 |
WO2006038611A1 (ja) | 2006-04-13 |
CN101027052A (zh) | 2007-08-29 |
CA2582339C (en) | 2014-04-22 |
US20090227651A1 (en) | 2009-09-10 |
JPWO2006038611A1 (ja) | 2008-05-15 |
CA2582339A1 (en) | 2006-04-13 |
US20100137399A1 (en) | 2010-06-03 |
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