KR100911073B1 - 이미다졸 유도체의 결정 형태 - Google Patents
이미다졸 유도체의 결정 형태 Download PDFInfo
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- KR100911073B1 KR100911073B1 KR1020077020701A KR20077020701A KR100911073B1 KR 100911073 B1 KR100911073 B1 KR 100911073B1 KR 1020077020701 A KR1020077020701 A KR 1020077020701A KR 20077020701 A KR20077020701 A KR 20077020701A KR 100911073 B1 KR100911073 B1 KR 100911073B1
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- ethyl
- dimethyl
- phenyl
- amino
- imidazo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- Pain & Pain Management (AREA)
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- Ophthalmology & Optometry (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66059205P | 2005-03-11 | 2005-03-11 | |
| US60/660,592 | 2005-03-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20070103484A KR20070103484A (ko) | 2007-10-23 |
| KR100911073B1 true KR100911073B1 (ko) | 2009-08-06 |
Family
ID=36649530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077020701A Active KR100911073B1 (ko) | 2005-03-11 | 2006-03-01 | 이미다졸 유도체의 결정 형태 |
Country Status (22)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012503605A (ja) * | 2008-09-25 | 2012-02-09 | メルク カナダ インコーポレイテッド | Ep4受容体アンタゴニストとしてのベータ−カルボリンスルホニルウレア誘導体 |
| JP5668219B2 (ja) | 2009-04-22 | 2015-02-12 | ラクオリア創薬株式会社 | 癌治療のための選択的ep4受容体拮抗物質 |
| KR101780666B1 (ko) * | 2010-02-22 | 2017-09-21 | 에스크엣 인크. | Il-23 매개 질환의 치료에서 ep4 수용체 길항제의 용도 |
| RU2451680C1 (ru) | 2011-02-21 | 2012-05-27 | Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" | Клатратный комплекс циклодекстрина или арабиногалактана с 9-фенил-симм-октагидроселеноксантеном, способ его получения (варианты), фармацевтическая композиция и лекарственное средство |
| RU2464042C1 (ru) * | 2011-03-31 | 2012-10-20 | Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" | КЛАТРАТНЫЙ КОМПЛЕКС β-ЦИКЛОДЕКСТРИНА С ПРОИЗВОДНЫМ 5-ГИДРОКСИ-4-АМИНОМЕТИЛ-1-ЦИКЛОГЕКСИЛ(ИЛИ ЦИКЛОГЕПТИЛ)-3-АЛКОКСИКАРБОНИЛИНДОЛА, СПОСОБ ЕГО ПОЛУЧЕНИЯ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И ЛЕКАРСТВЕННОЕ СРЕДСТВО |
| KR102239641B1 (ko) * | 2013-03-19 | 2021-04-13 | 에스크엣 인크. | 연골질환 치료에서의 ep4 수용체 길항제의 용도 |
| US10391086B2 (en) | 2013-03-19 | 2019-08-27 | Askat Inc. | Use of EP4 receptor antagonists in the treatment of cartilage disease |
| RU2638931C1 (ru) * | 2014-03-06 | 2017-12-19 | Аратана Терапьютикс, Инк. | Кристаллические формы грапипранта |
| US12109218B2 (en) | 2014-12-09 | 2024-10-08 | Aratana Therapeutics, Inc. | Compositions of grapiprant and methods for using the same |
| KR102270323B1 (ko) * | 2014-03-06 | 2021-06-29 | 아라타나 세라퓨틱스, 인크. | 그라피프란트의 조성물 및 이를 사용하기 위한 방법 |
| US10342785B2 (en) | 2016-11-04 | 2019-07-09 | Askat Inc. | Use of EP4 receptor antagonists for the treatment of NASH-associated liver cancer |
| AU2019255196A1 (en) | 2018-04-16 | 2020-11-12 | Arrys Therapeutics, Inc. | EP4 inhibitors and use thereof |
| US10239885B1 (en) | 2018-06-18 | 2019-03-26 | Avista Pharma Solutions, Inc. | Compound 1-[2-[4-(2-ethyl-6,8-dimethylimidazo[1,2-α]pyrazin-3-yl)phenyl]ethyl]-3-(p-tolylsulfonyl)urea as a prostaglandin EP4 receptor antagonist |
| US20210315909A1 (en) | 2018-07-11 | 2021-10-14 | Arrys Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| JP2021530487A (ja) * | 2018-07-11 | 2021-11-11 | アリーズ セラピューティクス, インコーポレイテッド | Ep4阻害剤およびその合成 |
| US11459331B2 (en) | 2019-01-30 | 2022-10-04 | Avista Pharma Solutions, Inc. | Chemical compounds |
| CA3128346A1 (en) | 2019-01-30 | 2020-08-06 | Avista Pharma Solutions, Inc. | Synthetic process and novel intermediates |
| US11254675B2 (en) | 2019-08-12 | 2022-02-22 | Cadila Healthcare Limited | Process for preparation of grapiprant |
| WO2021226162A1 (en) | 2020-05-05 | 2021-11-11 | Arrys Therapeutics, Inc. | Ep4 antagonists and their use in the treatment of proliferative diseases |
| CN117616022A (zh) * | 2021-07-30 | 2024-02-27 | 拉夸里亚创药株式会社 | 晶形 |
| CN116478155B (zh) * | 2022-01-17 | 2025-06-13 | 洛阳惠中兽药有限公司 | 一种格拉匹伦及其中间体的制备方法 |
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| WO2002032900A2 (en) * | 2000-10-19 | 2002-04-25 | Pfizer Pharmaceuticals Inc. | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents |
Family Cites Families (2)
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| IL110296A (en) * | 1993-07-16 | 1999-12-31 | Smithkline Beecham Corp | Imidazole compounds process for their preparation and pharmaceutical compositions containing them |
| MXPA04009243A (es) * | 2002-04-12 | 2005-06-08 | Pfizer | Uso de ligandos para el receptor ep4 en el tratamiento de enfermedades vinculadas a il-6. |
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| Topics in Current Chemistry. 1998, 198, 163-208 |
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| IN2014DN09939A (cg-RX-API-DMAC10.html) | 2015-08-14 |
| US20090018158A1 (en) | 2009-01-15 |
| KR20070103484A (ko) | 2007-10-23 |
| CN101137656B (zh) | 2010-12-22 |
| WO2006095268A1 (en) | 2006-09-14 |
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| JP5069415B2 (ja) | 2012-11-07 |
| CN101137656A (zh) | 2008-03-05 |
| BRPI0608819A8 (pt) | 2017-10-10 |
| JP2006249089A (ja) | 2006-09-21 |
| BRPI0608819B1 (pt) | 2019-11-12 |
| RU2007133802A (ru) | 2009-03-20 |
| ES2344310T3 (es) | 2010-08-24 |
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| CA2600510A1 (en) | 2006-09-14 |
| RU2357968C1 (ru) | 2009-06-10 |
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| BRPI0608819A2 (pt) | 2010-01-26 |
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| MX2007011110A (es) | 2008-02-21 |
| PL1861400T3 (pl) | 2010-09-30 |
| CA2600510C (en) | 2010-11-02 |
| ATE469150T1 (de) | 2010-06-15 |
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