KR100897469B1 - 티에노피리미딘디온 및 그의 자가면역 질환의 조절에있어서의 용도 - Google Patents
티에노피리미딘디온 및 그의 자가면역 질환의 조절에있어서의 용도 Download PDFInfo
- Publication number
- KR100897469B1 KR100897469B1 KR1020047001192A KR20047001192A KR100897469B1 KR 100897469 B1 KR100897469 B1 KR 100897469B1 KR 1020047001192 A KR1020047001192 A KR 1020047001192A KR 20047001192 A KR20047001192 A KR 20047001192A KR 100897469 B1 KR100897469 B1 KR 100897469B1
- Authority
- KR
- South Korea
- Prior art keywords
- methyl
- pyrimidine
- dione
- thieno
- ylcarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 C*c1c(C(O)=O)c(C(N(*)C(N2*)=O)=O)c2[s]1 Chemical compound C*c1c(C(O)=O)c(C(N(*)C(N2*)=O)=O)c2[s]1 0.000 description 1
- PTJJPJONGJKOGF-UHFFFAOYSA-N CC(C)CN(c([s]c(C(c1c(C)[nH]c2c1cccc2)=O)c1C(N2OCCC2)=O)c1C(N1C)=O)C1=O Chemical compound CC(C)CN(c([s]c(C(c1c(C)[nH]c2c1cccc2)=O)c1C(N2OCCC2)=O)c1C(N1C)=O)C1=O PTJJPJONGJKOGF-UHFFFAOYSA-N 0.000 description 1
- WYJQORFNTUPLSQ-GTVARFKMSA-N CC(C)CN(c([s]c(C/C(/C)=C\C(\NC)=N/c1c(C)cccc1)c1C(N(C2)OC[C@H]2O)=O)c1C(N1C)=O)C1=O Chemical compound CC(C)CN(c([s]c(C/C(/C)=C\C(\NC)=N/c1c(C)cccc1)c1C(N(C2)OC[C@H]2O)=O)c1C(N1C)=O)C1=O WYJQORFNTUPLSQ-GTVARFKMSA-N 0.000 description 1
- HZTBDQUBNPWPSK-LBPRGKRZSA-N CC(C)CN(c([s]c(CC1=NC(C)=CNC1=O)c1C(N(C2)OC[C@H]2O)=O)c1C(N1C)=O)C1=O Chemical compound CC(C)CN(c([s]c(CC1=NC(C)=CNC1=O)c1C(N(C2)OC[C@H]2O)=O)c1C(N1C)=O)C1=O HZTBDQUBNPWPSK-LBPRGKRZSA-N 0.000 description 1
- BMJFGMRXIQQYEH-AWEZNQCLSA-N CC(C)CN(c([s]c(C[n]1nc(C)cc1C)c1C(N(C2)OC[C@H]2O)=O)c1C(N1C)=O)C1=O Chemical compound CC(C)CN(c([s]c(C[n]1nc(C)cc1C)c1C(N(C2)OC[C@H]2O)=O)c1C(N1C)=O)C1=O BMJFGMRXIQQYEH-AWEZNQCLSA-N 0.000 description 1
- PVYNJFMZRSKZRF-UHFFFAOYSA-O CC(C)N(c([s]c(CC(C(C)=N)=C(C)[NH3+])c1C(N(C2)OCC2O)=O)c1C(N1C)=O)C1=O Chemical compound CC(C)N(c([s]c(CC(C(C)=N)=C(C)[NH3+])c1C(N(C2)OCC2O)=O)c1C(N1C)=O)C1=O PVYNJFMZRSKZRF-UHFFFAOYSA-O 0.000 description 1
- RECMMXWFDZIIOE-HNNXBMFYSA-N CCc1nc(cccc2)c2[n]1Cc1c(C(N(C2)OC[C@H]2O)=O)c(C(N(C)C(N2CC(C)C)=O)=O)c2[s]1 Chemical compound CCc1nc(cccc2)c2[n]1Cc1c(C(N(C2)OC[C@H]2O)=O)c(C(N(C)C(N2CC(C)C)=O)=O)c2[s]1 RECMMXWFDZIIOE-HNNXBMFYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- AIDS & HIV (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0118479.5 | 2001-07-28 | ||
| GBGB0118479.5A GB0118479D0 (en) | 2001-07-28 | 2001-07-28 | Novel compounds |
| PCT/GB2002/003399 WO2003011868A1 (en) | 2001-07-28 | 2002-07-24 | Thienopyrimidinediones and their use in the modulation of autoimmune disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20040017355A KR20040017355A (ko) | 2004-02-26 |
| KR100897469B1 true KR100897469B1 (ko) | 2009-05-14 |
Family
ID=9919407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020047001192A Expired - Fee Related KR100897469B1 (ko) | 2001-07-28 | 2002-07-24 | 티에노피리미딘디온 및 그의 자가면역 질환의 조절에있어서의 용도 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7384950B2 (enExample) |
| EP (1) | EP1414825B9 (enExample) |
| JP (1) | JP4456364B2 (enExample) |
| KR (1) | KR100897469B1 (enExample) |
| CN (1) | CN1324033C (enExample) |
| AR (1) | AR038000A1 (enExample) |
| AT (1) | ATE374204T1 (enExample) |
| AU (1) | AU2002319469B2 (enExample) |
| BR (1) | BR0211262A (enExample) |
| CA (1) | CA2453274A1 (enExample) |
| DE (1) | DE60222671T2 (enExample) |
| ES (1) | ES2292784T3 (enExample) |
| GB (1) | GB0118479D0 (enExample) |
| HU (1) | HUP0402336A3 (enExample) |
| IL (2) | IL159785A0 (enExample) |
| IS (1) | IS2598B (enExample) |
| MX (1) | MXPA04000677A (enExample) |
| MY (1) | MY138145A (enExample) |
| NO (1) | NO328713B1 (enExample) |
| NZ (1) | NZ530495A (enExample) |
| PL (1) | PL211351B1 (enExample) |
| RU (1) | RU2294937C9 (enExample) |
| WO (1) | WO2003011868A1 (enExample) |
| ZA (1) | ZA200400574B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9801399D0 (sv) | 1998-04-21 | 1998-04-21 | Astra Pharma Prod | Method and apparatus for filling containers |
| GB0117583D0 (en) * | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
| GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
| US7718802B2 (en) | 2001-08-10 | 2010-05-18 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
| US7732451B2 (en) | 2001-08-10 | 2010-06-08 | Palatin Technologies, Inc. | Naphthalene-containing melanocortin receptor-specific small molecule |
| US7456184B2 (en) | 2003-05-01 | 2008-11-25 | Palatin Technologies Inc. | Melanocortin receptor-specific compounds |
| US7655658B2 (en) | 2001-08-10 | 2010-02-02 | Palatin Technologies, Inc. | Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds |
| JP2005504043A (ja) | 2001-08-10 | 2005-02-10 | パラチン テクノロジーズ インク． | 生物学的に活性な金属ペプチド類のペプチド模倣体類 |
| AU2003246972A1 (en) | 2002-08-06 | 2004-02-23 | Astrazeneca Ab | Condensed pyridines and pyrimidines with tie2 (tek) activity |
| US6890923B2 (en) * | 2002-12-16 | 2005-05-10 | Astrazeneca Ab | Compounds |
| SE0300120D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
| SE0300119D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
| EP1587811A1 (en) * | 2003-01-17 | 2005-10-26 | AstraZeneca AB | Thienopyridazinones and their use in modulation of autoimmune disease |
| JP2006519846A (ja) * | 2003-03-10 | 2006-08-31 | シェーリング コーポレイション | 複素環式キナーゼインヒビター：使用および合成の方法 |
| US7727990B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine and keto-piperazine compounds |
| US7968548B2 (en) * | 2003-05-01 | 2011-06-28 | Palatin Technologies, Inc. | Melanocortin receptor-specific piperazine compounds with diamine groups |
| US7727991B2 (en) | 2003-05-01 | 2010-06-01 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific single acyl piperazine compounds |
| ES2527118T3 (es) | 2003-12-19 | 2015-01-20 | Plexxikon Inc. | Compuestos y procedimientos de desarrollo de moduladores de Ret |
| US7550602B1 (en) | 2004-01-14 | 2009-06-23 | Palatin Technologies, Inc. | Small molecule compositions for sexual dysfunction |
| US7709484B1 (en) | 2004-04-19 | 2010-05-04 | Palatin Technologies, Inc. | Substituted melanocortin receptor-specific piperazine compounds |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| EP1781285A2 (en) * | 2004-08-18 | 2007-05-09 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
| NZ563444A (en) | 2005-05-17 | 2011-04-29 | Plexxikon Inc | Pyrrolo(2,3-b)pyridine derivatives as protein kinase inhibitors |
| UA95244C2 (ru) | 2005-06-22 | 2011-07-25 | Плексикон, Инк. | Соединения и способ модулирования активности киназ, и показания для их применения |
| US7834017B2 (en) | 2006-08-11 | 2010-11-16 | Palatin Technologies, Inc. | Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| SG183036A1 (en) | 2007-07-17 | 2012-08-30 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
| RU2345996C1 (ru) * | 2007-07-17 | 2009-02-10 | Андрей Александрович Иващенко | Аннелированные азагетероциклические амиды, включающие пиримидиновый фрагмент, способ их получения и применения |
| RU2341527C1 (ru) * | 2007-07-17 | 2008-12-20 | Общество С Ограниченной Ответственностью "Исследовательский Институт Химического Разнообразия" | Аннелированные азагетероциклы, включающие пиримидиновый фрагмент, способ их получения и ингибиторы pi3k киназ |
| CA2711713A1 (en) * | 2008-01-22 | 2009-07-30 | Boehringer Ingelheim International Gmbh | Substituted amino-benzimidazoles, medicaments comprising said compound, their use and their method of manufacture |
| AU2010227225A1 (en) * | 2009-03-23 | 2011-09-15 | Glenmark Pharmaceuticals, S.A. | Furopyrimidinedione derivatives as TRPA1 modulators |
| EA022924B1 (ru) | 2009-04-03 | 2016-03-31 | Ф.Хоффманн-Ля Рош Аг | ТВЁРДАЯ ФОРМА {3-[5-(4-ХЛОРФЕНИЛ)-1Н-ПИРРОЛО[2,3-b]ПИРИДИН-3-КАРБОНИЛ]-2,4-ДИФТОРФЕНИЛ}АМИДА ПРОПАН-1-СУЛЬФОНОВОЙ КИСЛОТЫ И ЕЁ ПРИМЕНЕНИЕ |
| MA33975B1 (fr) | 2009-11-06 | 2013-02-01 | Plexxikon Inc | Composés et méthodes de modulation des kinases et leurs indications d'emploi |
| JP5941069B2 (ja) | 2011-02-07 | 2016-06-29 | プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． | キナーゼ調節のための化合物および方法、ならびにそれに対する適応症 |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| JP5990980B2 (ja) * | 2012-04-02 | 2016-09-14 | 大日本印刷株式会社 | オランザピンの中間体の製造方法 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| AR117469A1 (es) | 2018-12-21 | 2021-08-11 | Merck Patent Gmbh | Derivados de alquino disustituidos |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998054190A1 (en) * | 1997-05-28 | 1998-12-03 | Astra Pharmaceuticals Ltd. | Novel compounds |
| WO2000012514A1 (en) * | 1998-08-28 | 2000-03-09 | Astrazeneca Ab | Novel compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6469014B1 (en) * | 1997-05-28 | 2002-10-22 | Astrazeneca Ab | Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy |
| DE69807741T2 (de) | 1997-12-05 | 2004-07-15 | Astrazeneca Uk Ltd. | Neuartige verbindungen |
| US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| GB0117583D0 (en) * | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
| GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
| SE0300120D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
| SE0300119D0 (sv) | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
| EP1587811A1 (en) | 2003-01-17 | 2005-10-26 | AstraZeneca AB | Thienopyridazinones and their use in modulation of autoimmune disease |
-
2001
- 2001-07-28 GB GBGB0118479.5A patent/GB0118479D0/en not_active Ceased
-
2002
- 2002-07-24 EP EP02749055A patent/EP1414825B9/en not_active Expired - Lifetime
- 2002-07-24 AT AT02749055T patent/ATE374204T1/de not_active IP Right Cessation
- 2002-07-24 HU HU0402336A patent/HUP0402336A3/hu unknown
- 2002-07-24 MX MXPA04000677A patent/MXPA04000677A/es active IP Right Grant
- 2002-07-24 WO PCT/GB2002/003399 patent/WO2003011868A1/en not_active Ceased
- 2002-07-24 KR KR1020047001192A patent/KR100897469B1/ko not_active Expired - Fee Related
- 2002-07-24 BR BR0211262-0A patent/BR0211262A/pt not_active IP Right Cessation
- 2002-07-24 DE DE60222671T patent/DE60222671T2/de not_active Expired - Lifetime
- 2002-07-24 RU RU2004102392/04A patent/RU2294937C9/ru not_active IP Right Cessation
- 2002-07-24 ES ES02749055T patent/ES2292784T3/es not_active Expired - Lifetime
- 2002-07-24 IL IL15978502A patent/IL159785A0/xx unknown
- 2002-07-24 NZ NZ530495A patent/NZ530495A/en not_active IP Right Cessation
- 2002-07-24 CN CNB028152506A patent/CN1324033C/zh not_active Expired - Fee Related
- 2002-07-24 CA CA002453274A patent/CA2453274A1/en not_active Abandoned
- 2002-07-24 US US10/483,162 patent/US7384950B2/en not_active Expired - Fee Related
- 2002-07-24 PL PL369232A patent/PL211351B1/pl not_active IP Right Cessation
- 2002-07-24 JP JP2003517059A patent/JP4456364B2/ja not_active Expired - Fee Related
- 2002-07-24 AU AU2002319469A patent/AU2002319469B2/en not_active Ceased
- 2002-07-26 AR ARP020102842A patent/AR038000A1/es active IP Right Grant
- 2002-07-26 MY MYPI20022835A patent/MY138145A/en unknown
-
2004
- 2004-01-08 IL IL159785A patent/IL159785A/en not_active IP Right Cessation
- 2004-01-19 IS IS7118A patent/IS2598B/is unknown
- 2004-01-26 ZA ZA200400574A patent/ZA200400574B/en unknown
- 2004-01-27 NO NO20040364A patent/NO328713B1/no not_active IP Right Cessation
-
2008
- 2008-04-29 US US12/111,792 patent/US20080207642A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998054190A1 (en) * | 1997-05-28 | 1998-12-03 | Astra Pharmaceuticals Ltd. | Novel compounds |
| WO2000012514A1 (en) * | 1998-08-28 | 2000-03-09 | Astrazeneca Ab | Novel compounds |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100897469B1 (ko) | 티에노피리미딘디온 및 그의 자가면역 질환의 조절에있어서의 용도 | |
| US7361660B2 (en) | Chemical compounds | |
| AU2004206012B2 (en) | Thienopyrimidinediones and their use in the modulation of autoimmune disease | |
| AU2002319469A1 (en) | Thienopyrimidinediones and their use in the modulation of autoimmune disease | |
| EP1107973B1 (en) | NOVEL THIENO[2,3-d]PYRIMIDINEDIONES, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN THERAPY | |
| US20080221131A1 (en) | Thienopyrimidinediones and their use in modulation of autoimmune disease | |
| HK1065785B (en) | Thienopyrimidinediones and their use in the modulation of autoimmune disease | |
| HK1065542B (en) | THIENO(2,3-d)PYRIMIDINEDIONES AS INHIBITORS OF T-CELLS SPROLIFERATION |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-3-3-R10-R18-oth-X000 |
|
| A201 | Request for examination | ||
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| FPAY | Annual fee payment |
Payment date: 20120423 Year of fee payment: 4 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20130507 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20130507 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |