KR100880859B1 - 자발분산성 ｎ-벤조일-스타우로스포린 조성물 - Google Patents

자발분산성 ｎ-벤조일-스타우로스포린 조성물 Download PDF

Info

Publication number
KR100880859B1
KR100880859B1 KR1020017009391A KR20017009391A KR100880859B1 KR 100880859 B1 KR100880859 B1 KR 100880859B1 KR 1020017009391 A KR1020017009391 A KR 1020017009391A KR 20017009391 A KR20017009391 A KR 20017009391A KR 100880859 B1 KR100880859 B1 KR 100880859B1
Authority
KR
South Korea
Prior art keywords
weight
benzoyl
composition
staurosporin
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020017009391A
Other languages
English (en)
Korean (ko)
Other versions
KR20010093281A (ko
Inventor
매튜즈그라함폴
하베를린바르바라
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10847896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100880859(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20010093281A publication Critical patent/KR20010093281A/ko
Application granted granted Critical
Publication of KR100880859B1 publication Critical patent/KR100880859B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020017009391A 1999-02-16 2000-02-14 자발분산성 ｎ-벤조일-스타우로스포린 조성물 Expired - Lifetime KR100880859B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903547.9A GB9903547D0 (en) 1999-02-16 1999-02-16 Organic compounds
GB9903547.9 1999-02-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020087015449A Division KR20080064914A (ko) 1999-02-16 2000-02-14 자발분산성 ｎ-벤조일-스타우로스포린 조성물

Publications (2)

Publication Number Publication Date
KR20010093281A KR20010093281A (ko) 2001-10-27
KR100880859B1 true KR100880859B1 (ko) 2009-01-30

Family

ID=10847896

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020017009391A Expired - Lifetime KR100880859B1 (ko) 1999-02-16 2000-02-14 자발분산성 ｎ-벤조일-스타우로스포린 조성물
KR1020087015449A Withdrawn KR20080064914A (ko) 1999-02-16 2000-02-14 자발분산성 ｎ-벤조일-스타우로스포린 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020087015449A Withdrawn KR20080064914A (ko) 1999-02-16 2000-02-14 자발분산성 ｎ-벤조일-스타우로스포린 조성물

Country Status (34)

Country Link
US (3) US20020061873A1 (cg-RX-API-DMAC10.html)
EP (1) EP1152750B1 (cg-RX-API-DMAC10.html)
JP (2) JP5057610B2 (cg-RX-API-DMAC10.html)
KR (2) KR100880859B1 (cg-RX-API-DMAC10.html)
CN (1) CN100367930C (cg-RX-API-DMAC10.html)
AR (2) AR022589A1 (cg-RX-API-DMAC10.html)
AT (1) ATE430554T1 (cg-RX-API-DMAC10.html)
AU (1) AU765776B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0008228B8 (cg-RX-API-DMAC10.html)
CA (1) CA2362277C (cg-RX-API-DMAC10.html)
CL (1) CL2009001682A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ303979B6 (cg-RX-API-DMAC10.html)
DE (1) DE60042151D1 (cg-RX-API-DMAC10.html)
DK (1) DK1152750T3 (cg-RX-API-DMAC10.html)
EC (1) ECSP083351A (cg-RX-API-DMAC10.html)
ES (1) ES2326783T3 (cg-RX-API-DMAC10.html)
GB (1) GB9903547D0 (cg-RX-API-DMAC10.html)
HK (1) HK1045807B (cg-RX-API-DMAC10.html)
HU (1) HUP0105364A3 (cg-RX-API-DMAC10.html)
ID (1) ID30504A (cg-RX-API-DMAC10.html)
IL (3) IL144512A0 (cg-RX-API-DMAC10.html)
MY (1) MY128362A (cg-RX-API-DMAC10.html)
NO (1) NO331232B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ513529A (cg-RX-API-DMAC10.html)
PE (1) PE20001499A1 (cg-RX-API-DMAC10.html)
PL (1) PL198330B1 (cg-RX-API-DMAC10.html)
PT (1) PT1152750E (cg-RX-API-DMAC10.html)
RU (1) RU2266121C2 (cg-RX-API-DMAC10.html)
SI (1) SI1152750T1 (cg-RX-API-DMAC10.html)
SK (1) SK286967B6 (cg-RX-API-DMAC10.html)
TR (1) TR200102385T2 (cg-RX-API-DMAC10.html)
TW (1) TWI240636B (cg-RX-API-DMAC10.html)
WO (1) WO2000048571A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA200106677B (cg-RX-API-DMAC10.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US7795246B2 (en) 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
WO2002076432A2 (en) * 2001-03-26 2002-10-03 Novartis Ag Pharmaceutical composition comprising a poorly water-soluble active ingredient, a surfactant and a water-soluble polymer
AU2002342335B2 (en) 2001-05-16 2006-02-02 Novartis Ag Combination comprising N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent
PT1441737E (pt) * 2001-10-30 2006-12-29 Dana Farber Cancer Inst Inc Derivados de estrutura como inibidores da actividade do receptor de tirosina cinase flt3
GB0206215D0 (en) 2002-03-15 2002-05-01 Novartis Ag Organic compounds
CN101897662B (zh) * 2002-07-23 2013-05-22 诺瓦提斯公司 包含药物、软膏基质和增溶剂/分散剂的眼用软膏剂组合物
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
GB0512324D0 (en) 2005-06-16 2005-07-27 Novartis Ag Organic compounds
GB0419159D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
GT200500310A (es) 2004-11-19 2006-06-19 Compuestos organicos
WO2008021347A2 (en) * 2006-08-16 2008-02-21 Novartis Ag Method for making solid dispersions of highly crystalline therapeutic compounds
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
WO2009067221A2 (en) * 2007-11-20 2009-05-28 Cephalon, Inc. Microemulsion containing indolocarbazole compound and dosage forms containing the same
EP2229936B1 (en) * 2009-03-09 2015-05-06 PharmaSol GmbH Nanonized testosterone formulations for improved bioavailability
WO2011000811A2 (en) * 2009-06-30 2011-01-06 Novartis Ag Organic compounds
RU2560677C2 (ru) * 2009-12-22 2015-08-20 Лео Фарма А/С Кожная композиция, включающая аналог витамина d и смесь растворителя и поверхностно-активных веществ
JO3337B1 (ar) * 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
WO2013042069A1 (en) 2011-09-22 2013-03-28 Ariel-University Research And Development Company, Ltd. Emulsions and methods of making emulsions
RU2742650C2 (ru) * 2015-12-09 2021-02-09 Фосфейдженикс Лимитед Фармацевтический состав
US10973761B2 (en) 2015-12-09 2021-04-13 Phosphagenics Limited Pharmaceutical formulation
JP7198754B2 (ja) 2016-12-21 2023-01-04 アベーチョ バイオテクノロジー リミテッド 方法
WO2021097256A1 (en) 2019-11-14 2021-05-20 Cohbar, Inc. Cxcr4 antagonist peptides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0657164A1 (en) * 1993-12-11 1995-06-14 Ciba-Geigy Ag Pharmaceutical compositions containing staurosphorine derivatives
EP0733358A2 (de) * 1995-03-21 1996-09-25 Ciba-Geigy Ag Intravenös applizierbare Nanosuspensionen

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4735939A (en) 1987-02-27 1988-04-05 The Dow Chemical Company Insecticidal activity of staurosporine
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
DE3824034C1 (cg-RX-API-DMAC10.html) * 1988-07-15 1989-09-14 Gustav 7290 Freudenstadt De Memminger
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
DE69229779T2 (de) 1991-04-19 1999-12-23 Lds Technologies, Inc. Konvertierbare mikroemulsionsverbindungen
GB9113872D0 (en) 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
US6306421B1 (en) * 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
DK0589843T3 (da) * 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
US5639474A (en) 1993-07-01 1997-06-17 Hanmi Pharm. Ind., Ltd. Cyclosporin soft capsule composition
JPH09510182A (ja) 1993-11-17 1997-10-14 エルディーエス・テクノロジーズ・インコーポレーテッド カプセル封入されたドラッグデリバリー用透明液
WO1995022331A1 (en) 1994-02-18 1995-08-24 Cephalon, Inc. Aqueous indolocarbazole solutions
WO1995032975A1 (en) * 1994-06-01 1995-12-07 Ciba-Geigy Ag Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agents
MY129435A (en) * 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
GB2308545B (en) 1994-10-26 1999-06-02 Novartis Ag Pharmaceutical microemulsion preconcentrates
EP0711556A1 (de) * 1994-11-09 1996-05-15 Ciba-Geigy Ag Intravenöse Lösungen für ein Staurosporinderivat
WO1998013032A1 (en) 1996-09-27 1998-04-02 Trega Biosciences, Inc. Compositions of therapeutic agents suitable for oral administration
DE19641672A1 (de) 1996-10-10 1998-04-16 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen auf der Basis von ethylenoxidfreien und propylenoxidfreien Emulgatoren zur Herstellung von Mikroemulsionsgelen
US5827522A (en) 1996-10-30 1998-10-27 Troy Corporation Microemulsion and method
NZ314060A (en) 1997-01-13 1997-08-22 Bernard Charles Sherman Pharmaceutical microemulsion preconcentrate comprising cyclosporin dissolved in a solvent system comprising hydrophobic solvent(s) and surfactant(s)
PT988046E (pt) * 1997-01-30 2004-12-31 Novartis Ag Composicoes farmaceuticas sem oleo contendo ciclosporina a
SI0999826T1 (en) 1997-07-29 2004-12-31 Pharmacia & Upjohn Company Self-emulsifying formulation for lipophilic compounds
DK0999838T3 (da) 1997-07-29 2002-07-08 Upjohn Co Selv-emulgerende formulering for lipofile forbindelser
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6979456B1 (en) * 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
GB9814527D0 (en) * 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system
AR013276A1 (es) 1998-07-31 2000-12-13 Panacea Biotec Ltd Composicion de ciclosporina transparente
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0657164A1 (en) * 1993-12-11 1995-06-14 Ciba-Geigy Ag Pharmaceutical compositions containing staurosphorine derivatives
EP0733358A2 (de) * 1995-03-21 1996-09-25 Ciba-Geigy Ag Intravenös applizierbare Nanosuspensionen

Also Published As

Publication number Publication date
PL198330B1 (pl) 2008-06-30
AR022589A1 (es) 2002-09-04
WO2000048571A1 (en) 2000-08-24
HUP0105364A2 (hu) 2002-05-29
JP2002537242A (ja) 2002-11-05
NZ513529A (en) 2003-10-31
GB9903547D0 (en) 1999-04-07
CN100367930C (zh) 2008-02-13
US20140056974A1 (en) 2014-02-27
ATE430554T1 (de) 2009-05-15
US8722664B2 (en) 2014-05-13
IL144512A0 (en) 2002-05-23
US8575147B2 (en) 2013-11-05
SI1152750T1 (sl) 2009-10-31
DK1152750T3 (da) 2009-08-24
NO20013964D0 (no) 2001-08-15
JP5057610B2 (ja) 2012-10-24
CZ303979B6 (cs) 2013-07-31
BRPI0008228B8 (pt) 2021-05-25
NO20013964L (no) 2001-10-15
BR0008228A (pt) 2001-10-30
AR082579A2 (es) 2012-12-19
HK1045807B (zh) 2008-12-05
CA2362277A1 (en) 2000-08-24
HK1045807A1 (zh) 2002-12-13
KR20080064914A (ko) 2008-07-09
CA2362277C (en) 2010-03-30
KR20010093281A (ko) 2001-10-27
RU2266121C2 (ru) 2005-12-20
ECSP083351A (es) 2008-08-29
PT1152750E (pt) 2009-08-07
BRPI0008228B1 (pt) 2016-08-23
EP1152750A1 (en) 2001-11-14
AU3154200A (en) 2000-09-04
DE60042151D1 (de) 2009-06-18
PL350556A1 (en) 2002-12-16
US20020061873A1 (en) 2002-05-23
IL192666A0 (en) 2009-02-11
MY128362A (en) 2007-01-31
JP2012111763A (ja) 2012-06-14
SK286967B6 (sk) 2009-08-06
HUP0105364A3 (en) 2003-02-28
CN1339963A (zh) 2002-03-13
PE20001499A1 (es) 2001-01-12
IL144512A (en) 2011-03-31
CZ20012931A3 (cs) 2001-11-14
EP1152750B1 (en) 2009-05-06
SK11722001A3 (sk) 2001-12-03
US20080070897A1 (en) 2008-03-20
ES2326783T3 (es) 2009-10-20
AU765776B2 (en) 2003-10-02
CL2009001682A1 (es) 2010-07-23
TWI240636B (en) 2005-10-01
ZA200106677B (en) 2003-01-14
ID30504A (id) 2001-12-13
TR200102385T2 (tr) 2002-09-23
NO331232B1 (no) 2011-11-07

Similar Documents

Publication Publication Date Title
US8722664B2 (en) Spontaneously dispersible N-benzoyl staurosporine compositions
AU765935B2 (en) Substantially oil-free cyclosporin compositions
EP1082119B1 (en) Microemulsion preconcentrates containing a piperidine substance p antagonist
RU2397759C2 (ru) Микроэмульсионные композиции, включающие антагонисты вещества р
HK1035137B (en) Microemulsion preconcentrates containing a piperidine substance p antagonist
MXPA01008293A (en) Spontaneously dispersible n-benzoyl staurosporine compositions
ZA200006597B (en) Microemulsion preconcentrates containing a piperidine substance p antagonist.

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20010726

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
AMND Amendment
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20050111

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20060622

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20080225

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20060622

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20080527

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20080225

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20081020

Appeal identifier: 2008101004762

Request date: 20080527

A107 Divisional application of patent
AMND Amendment
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20080625

PB0901 Examination by re-examination before a trial

Comment text: Amendment to Specification, etc.

Patent event date: 20080625

Patent event code: PB09011R02I

Comment text: Request for Trial against Decision on Refusal

Patent event date: 20080527

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20071218

Patent event code: PB09011R02I

Comment text: Amendment to Specification, etc.

Patent event date: 20050111

Patent event code: PB09011R02I

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20080801

Patent event code: PE09021S01D

B701 Decision to grant
PB0701 Decision of registration after re-examination before a trial

Patent event date: 20081020

Comment text: Decision to Grant Registration

Patent event code: PB07012S01D

Patent event date: 20080703

Comment text: Transfer of Trial File for Re-examination before a Trial

Patent event code: PB07011S01I

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20090121

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20090122

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20120109

Start annual number: 4

End annual number: 4

FPAY Annual fee payment

Payment date: 20130107

Year of fee payment: 5

PR1001 Payment of annual fee

Payment date: 20130107

Start annual number: 5

End annual number: 5

FPAY Annual fee payment

Payment date: 20140103

Year of fee payment: 6

PR1001 Payment of annual fee

Payment date: 20140103

Start annual number: 6

End annual number: 6

FPAY Annual fee payment

Payment date: 20150106

Year of fee payment: 7

PR1001 Payment of annual fee

Payment date: 20150106

Start annual number: 7

End annual number: 7

FPAY Annual fee payment

Payment date: 20151217

Year of fee payment: 8

PR1001 Payment of annual fee

Payment date: 20151217

Start annual number: 8

End annual number: 8

FPAY Annual fee payment

Payment date: 20170102

Year of fee payment: 9

PR1001 Payment of annual fee

Payment date: 20170102

Start annual number: 9

End annual number: 9

FPAY Annual fee payment

Payment date: 20180103

Year of fee payment: 10

PR1001 Payment of annual fee

Payment date: 20180103

Start annual number: 10

End annual number: 10

FPAY Annual fee payment

Payment date: 20190103

Year of fee payment: 11

PR1001 Payment of annual fee

Payment date: 20190103

Start annual number: 11

End annual number: 11

A101 Application to extend term of patent right by permit
PA0101 Application to register extension of term of patent right by permit, etc.

Patent event date: 20190514

Patent event code: PA01011R01D

Comment text: Application to Register Extension of Term of Patent Right by Permit, etc.

FPAY Annual fee payment

Payment date: 20200103

Year of fee payment: 12

PR1001 Payment of annual fee

Payment date: 20200103

Start annual number: 12

End annual number: 12

PR1001 Payment of annual fee

Payment date: 20210108

Start annual number: 13

End annual number: 13

PC1801 Expiration of term

Termination date: 20211019

Termination category: Expiration of duration