KR100849103B1 - 산화질소 흡입의 치료 효능 향상 - Google Patents

산화질소 흡입의 치료 효능 향상 Download PDF

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KR100849103B1
KR100849103B1 KR1020027017893A KR20027017893A KR100849103B1 KR 100849103 B1 KR100849103 B1 KR 100849103B1 KR 1020027017893 A KR1020027017893 A KR 1020027017893A KR 20027017893 A KR20027017893 A KR 20027017893A KR 100849103 B1 KR100849103 B1 KR 100849103B1
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South Korea
Prior art keywords
mammal
inhalation
pulmonary
nitric oxide
endotoxin
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Korean (ko)
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KR20030029530A (ko
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케네스 브로크
이치노세후미토
와렌엠 자폴
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더 제너럴 하스피탈 코포레이션
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020027017893A 2000-06-28 2001-06-22 산화질소 흡입의 치료 효능 향상 Expired - Fee Related KR100849103B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/605,900 2000-06-28
US09/605,900 US6601580B1 (en) 2000-06-28 2000-06-28 Enhancing therapeutic effectiveness of nitric oxide inhalation
PCT/US2001/041102 WO2002000175A2 (en) 2000-06-28 2001-06-22 Enhancing therapeutic effectiveness of nitric oxide inhalation

Publications (2)

Publication Number Publication Date
KR20030029530A KR20030029530A (ko) 2003-04-14
KR100849103B1 true KR100849103B1 (ko) 2008-07-30

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Country Status (10)

Country Link
US (2) US6601580B1 (enExample)
EP (1) EP1301076A4 (enExample)
JP (1) JP2004509850A (enExample)
KR (1) KR100849103B1 (enExample)
CN (1) CN100488497C (enExample)
AU (2) AU2001273622B2 (enExample)
CA (1) CA2414409A1 (enExample)
IL (1) IL153702A0 (enExample)
MX (1) MXPA03000182A (enExample)
WO (1) WO2002000175A2 (enExample)

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US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
GB0125357D0 (en) * 2001-10-22 2001-12-12 Univ Brighton Improvements relating to catalytic antioxidants
CN1596111A (zh) * 2001-11-29 2005-03-16 桑得医药品公司 减轻化疗引起的不良效果的组合物及方法
PT1471902E (pt) * 2002-01-04 2014-09-09 Sound Pharmaceuticals Inc Métodos para o tratamento da perda de audição
EA200500062A1 (ru) * 2002-06-21 2005-06-30 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Фармацевтическое применение оксида азота, гемоксигеназы-1 и продуктов деградации гема
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
US9138707B2 (en) 2002-12-10 2015-09-22 Sy Kimball Portable, nitric oxide generator
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
AU2004257693B8 (en) 2003-07-09 2009-08-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
MXPA06013111A (es) * 2004-05-11 2007-05-23 Sensormedics Corp Dosificacion intermitente de gas de oxido nitrico.
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
AU2006220626A1 (en) * 2005-03-08 2006-09-14 Sound Pharmaceuticals Incorporated Methods and compositions for treating cancer
US8557300B2 (en) * 2005-05-19 2013-10-15 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
WO2007057763A2 (en) * 2005-11-18 2007-05-24 Pulmonox Technologies Corporation Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
US8790715B2 (en) 2006-02-16 2014-07-29 Ino Therapeutics Llc Method and apparatus for generating nitric oxide for medical use
WO2007136789A2 (en) * 2006-05-19 2007-11-29 Medimmune, Inc. Methods of preventing, treating or ameliorating enhanced respiratory disease via innate immune mechanisms
FR2902002B1 (fr) * 2006-06-12 2010-08-27 Lvmh Rech Composition cosmetique anti-radicaux libres
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
TWI474824B (zh) * 2006-11-07 2015-03-01 Gen Hospital Corp 血管活性氧載劑所引發之血管收縮之減輕
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
WO2009063226A2 (en) * 2007-11-12 2009-05-22 Karolinska Institutet Innovations Ab Methods relating to breathing disorders
AU2008345034A1 (en) * 2007-12-27 2009-07-09 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide - donating compounds and uses thereof
US9649467B2 (en) 2008-01-31 2017-05-16 Syk Technologies, Llc Nitric oxide reactor and distributor apparatus and method
US8434475B2 (en) 2008-01-31 2013-05-07 Genosys, Inc. Nitric oxide reactor and distributor apparatus and method
US8720436B2 (en) * 2008-01-31 2014-05-13 Genosys, Inc. Nitric oxide gel apparatus and method
US8501090B2 (en) * 2008-03-24 2013-08-06 Christian S. Minton Anti-microbial gas apparatus and method
JP2011010865A (ja) 2009-06-30 2011-01-20 Ikaria Holdings Inc 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法
JP5581500B2 (ja) * 2010-03-10 2014-09-03 学校法人北里研究所 虚血再灌流障害軽減用治療剤および治療装置
US8685467B2 (en) 2010-08-03 2014-04-01 J. W. Randolph Miller Nitric oxide generation, dilution, and topical application apparatus and method
WO2012131412A2 (en) 2011-03-31 2012-10-04 Szabo Laszlo Gabor Pharmaceutical composition containing no, process for the preparation and use thereof
JP6389125B2 (ja) 2011-11-07 2018-09-12 ザ ジェネラル ホスピタル コーポレイション 赤血球の処理法
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
EP2908137A1 (en) * 2014-02-14 2015-08-19 Institut Pasteur Methods for in vitro investigating mitochondrial replication dysfunction in a biological sample, kits and uses thereof, therapeutic methods against progeroid-like syndromes or symptomes and screening method for identifying particular protease inhibitor(s) and/or nitroso-redox stress scavenger compound(s)
JP2014141536A (ja) * 2014-05-16 2014-08-07 Kitasato Institute 虚血再灌流障害軽減用治療剤および治療装置
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
US20170182088A1 (en) * 2015-12-28 2017-06-29 Geno Llc Method and apparatus for administering nitric oxide with supplemental drugs
WO2017132275A1 (en) 2016-01-27 2017-08-03 Syk Technologies, Llc Nitric oxide topical application apparatus and methods
US11602555B2 (en) 2016-11-17 2023-03-14 Renovion, Inc. Treatment of respiratory tract diseases and infections with ascorbic acid compositions
ES3008699T3 (en) 2017-11-17 2025-03-24 Renovion Inc Stable ascorbic acid compositions and methods of using the same
CN109169638A (zh) * 2018-11-12 2019-01-11 苏州瑞徕生物科技有限公司 一种细胞保存液及其用途
US12459820B2 (en) 2020-06-11 2025-11-04 J. W. Randolph Miller Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy
KR20240131358A (ko) 2022-01-04 2024-08-30 레노비온, 아이엔씨. 글루타치온 염을 포함하는 수용액

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WO1999037616A1 (en) * 1998-01-22 1999-07-29 Aenggaard Erik Emil Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress

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WO1999037616A1 (en) * 1998-01-22 1999-07-29 Aenggaard Erik Emil Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress

Also Published As

Publication number Publication date
EP1301076A2 (en) 2003-04-16
US20030202969A1 (en) 2003-10-30
AU7362201A (en) 2002-01-08
CA2414409A1 (en) 2002-01-03
US6601580B1 (en) 2003-08-05
IL153702A0 (en) 2003-07-06
AU2001273622B2 (en) 2007-05-10
JP2004509850A (ja) 2004-04-02
US6935334B2 (en) 2005-08-30
CN1635923A (zh) 2005-07-06
MXPA03000182A (es) 2004-02-26
WO2002000175A2 (en) 2002-01-03
WO2002000175A3 (en) 2002-08-15
KR20030029530A (ko) 2003-04-14
CN100488497C (zh) 2009-05-20
EP1301076A4 (en) 2004-09-22

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