KR100849103B1 - 산화질소 흡입의 치료 효능 향상 - Google Patents
산화질소 흡입의 치료 효능 향상 Download PDFInfo
- Publication number
- KR100849103B1 KR100849103B1 KR1020027017893A KR20027017893A KR100849103B1 KR 100849103 B1 KR100849103 B1 KR 100849103B1 KR 1020027017893 A KR1020027017893 A KR 1020027017893A KR 20027017893 A KR20027017893 A KR 20027017893A KR 100849103 B1 KR100849103 B1 KR 100849103B1
- Authority
- KR
- South Korea
- Prior art keywords
- mammal
- inhalation
- pulmonary
- nitric oxide
- endotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/605,900 | 2000-06-28 | ||
| US09/605,900 US6601580B1 (en) | 2000-06-28 | 2000-06-28 | Enhancing therapeutic effectiveness of nitric oxide inhalation |
| PCT/US2001/041102 WO2002000175A2 (en) | 2000-06-28 | 2001-06-22 | Enhancing therapeutic effectiveness of nitric oxide inhalation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20030029530A KR20030029530A (ko) | 2003-04-14 |
| KR100849103B1 true KR100849103B1 (ko) | 2008-07-30 |
Family
ID=24425654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020027017893A Expired - Fee Related KR100849103B1 (ko) | 2000-06-28 | 2001-06-22 | 산화질소 흡입의 치료 효능 향상 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6601580B1 (enExample) |
| EP (1) | EP1301076A4 (enExample) |
| JP (1) | JP2004509850A (enExample) |
| KR (1) | KR100849103B1 (enExample) |
| CN (1) | CN100488497C (enExample) |
| AU (2) | AU2001273622B2 (enExample) |
| CA (1) | CA2414409A1 (enExample) |
| IL (1) | IL153702A0 (enExample) |
| MX (1) | MXPA03000182A (enExample) |
| WO (1) | WO2002000175A2 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656452B1 (en) | 1997-10-21 | 2003-12-02 | The General Hospital Corporation | Use of inhaled NO as anti-inflammatory agent |
| CA2254645A1 (en) * | 1998-11-23 | 2000-05-23 | Pulmonox Medical Corporation | Method and apparatus for treatment of respiratory infections by nitric oxide inhalation |
| US20070086954A1 (en) * | 1998-11-23 | 2007-04-19 | Miller Christopher C | Method and apparatus for treatment of respiratory infections by nitric oxide inhalation |
| US7516742B2 (en) * | 1999-11-24 | 2009-04-14 | Cardinal Health 207, Inc. | Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing |
| US7335181B2 (en) * | 2000-12-26 | 2008-02-26 | Pulmonox Technologies Corporation | Nitric oxide decontamination of the upper respiratory tract |
| US6432077B1 (en) * | 2000-12-26 | 2002-08-13 | Sensormedics Corporation | Device and method for treatment of surface infections with nitric oxide |
| US7122018B2 (en) * | 2000-12-26 | 2006-10-17 | Sensormedics Corporation | Device and method for treatment of wounds with nitric oxide |
| GB0125222D0 (en) * | 2001-10-19 | 2001-12-12 | Barts & London Nhs Trust | Composition for the treatment of microbial infections |
| GB0125357D0 (en) * | 2001-10-22 | 2001-12-12 | Univ Brighton | Improvements relating to catalytic antioxidants |
| CN1596111A (zh) * | 2001-11-29 | 2005-03-16 | 桑得医药品公司 | 减轻化疗引起的不良效果的组合物及方法 |
| PT1471902E (pt) * | 2002-01-04 | 2014-09-09 | Sound Pharmaceuticals Inc | Métodos para o tratamento da perda de audição |
| EA200500062A1 (ru) * | 2002-06-21 | 2005-06-30 | Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн | Фармацевтическое применение оксида азота, гемоксигеназы-1 и продуктов деградации гема |
| US7531133B2 (en) * | 2002-09-10 | 2009-05-12 | Pulmonox Technologies Corporation | Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma |
| US9138707B2 (en) | 2002-12-10 | 2015-09-22 | Sy Kimball | Portable, nitric oxide generator |
| SE0300971D0 (sv) * | 2003-04-03 | 2003-04-03 | Aga Ab | Nitric oxide in treatment of inflammation |
| AU2004257693B8 (en) | 2003-07-09 | 2009-08-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of nitrite salts for the treatment of cardiovascular conditions |
| US20050255178A1 (en) * | 2004-02-04 | 2005-11-17 | Bloch Kenneth D | Enhancing the effectiveness of an inhaled therapeutic gas |
| US8518457B2 (en) * | 2004-05-11 | 2013-08-27 | Pulmonox Technologies Corporation | Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant |
| MXPA06013111A (es) * | 2004-05-11 | 2007-05-23 | Sensormedics Corp | Dosificacion intermitente de gas de oxido nitrico. |
| US7362274B1 (en) * | 2004-07-09 | 2008-04-22 | Huan-Cheng Lien | Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna |
| US20070154570A1 (en) * | 2004-09-29 | 2007-07-05 | Miller Christopher C | Use of nitric oxide in the treatment and disinfection of biofilms |
| AU2006220626A1 (en) * | 2005-03-08 | 2006-09-14 | Sound Pharmaceuticals Incorporated | Methods and compositions for treating cancer |
| US8557300B2 (en) * | 2005-05-19 | 2013-10-15 | University Of Cincinnati | Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite |
| WO2007057763A2 (en) * | 2005-11-18 | 2007-05-24 | Pulmonox Technologies Corporation | Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant |
| US8790715B2 (en) | 2006-02-16 | 2014-07-29 | Ino Therapeutics Llc | Method and apparatus for generating nitric oxide for medical use |
| WO2007136789A2 (en) * | 2006-05-19 | 2007-11-29 | Medimmune, Inc. | Methods of preventing, treating or ameliorating enhanced respiratory disease via innate immune mechanisms |
| FR2902002B1 (fr) * | 2006-06-12 | 2010-08-27 | Lvmh Rech | Composition cosmetique anti-radicaux libres |
| US8079998B2 (en) * | 2006-10-20 | 2011-12-20 | Pulmonox Technologies Corporation | Methods and devices for the delivery of therapeutic gases including nitric oxide |
| TWI474824B (zh) * | 2006-11-07 | 2015-03-01 | Gen Hospital Corp | 血管活性氧載劑所引發之血管收縮之減輕 |
| US20080193566A1 (en) * | 2007-02-09 | 2008-08-14 | Miller Christopher C | Use of high dose concentrations of gaseous nitric oxide |
| WO2009063226A2 (en) * | 2007-11-12 | 2009-05-22 | Karolinska Institutet Innovations Ab | Methods relating to breathing disorders |
| AU2008345034A1 (en) * | 2007-12-27 | 2009-07-09 | Aires Pharmaceuticals, Inc. | Aerosolized nitrite and nitric oxide - donating compounds and uses thereof |
| US9649467B2 (en) | 2008-01-31 | 2017-05-16 | Syk Technologies, Llc | Nitric oxide reactor and distributor apparatus and method |
| US8434475B2 (en) | 2008-01-31 | 2013-05-07 | Genosys, Inc. | Nitric oxide reactor and distributor apparatus and method |
| US8720436B2 (en) * | 2008-01-31 | 2014-05-13 | Genosys, Inc. | Nitric oxide gel apparatus and method |
| US8501090B2 (en) * | 2008-03-24 | 2013-08-06 | Christian S. Minton | Anti-microbial gas apparatus and method |
| JP2011010865A (ja) | 2009-06-30 | 2011-01-20 | Ikaria Holdings Inc | 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法 |
| JP5581500B2 (ja) * | 2010-03-10 | 2014-09-03 | 学校法人北里研究所 | 虚血再灌流障害軽減用治療剤および治療装置 |
| US8685467B2 (en) | 2010-08-03 | 2014-04-01 | J. W. Randolph Miller | Nitric oxide generation, dilution, and topical application apparatus and method |
| WO2012131412A2 (en) | 2011-03-31 | 2012-10-04 | Szabo Laszlo Gabor | Pharmaceutical composition containing no, process for the preparation and use thereof |
| JP6389125B2 (ja) | 2011-11-07 | 2018-09-12 | ザ ジェネラル ホスピタル コーポレイション | 赤血球の処理法 |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| EP2908137A1 (en) * | 2014-02-14 | 2015-08-19 | Institut Pasteur | Methods for in vitro investigating mitochondrial replication dysfunction in a biological sample, kits and uses thereof, therapeutic methods against progeroid-like syndromes or symptomes and screening method for identifying particular protease inhibitor(s) and/or nitroso-redox stress scavenger compound(s) |
| JP2014141536A (ja) * | 2014-05-16 | 2014-08-07 | Kitasato Institute | 虚血再灌流障害軽減用治療剤および治療装置 |
| US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
| US20170182088A1 (en) * | 2015-12-28 | 2017-06-29 | Geno Llc | Method and apparatus for administering nitric oxide with supplemental drugs |
| WO2017132275A1 (en) | 2016-01-27 | 2017-08-03 | Syk Technologies, Llc | Nitric oxide topical application apparatus and methods |
| US11602555B2 (en) | 2016-11-17 | 2023-03-14 | Renovion, Inc. | Treatment of respiratory tract diseases and infections with ascorbic acid compositions |
| ES3008699T3 (en) | 2017-11-17 | 2025-03-24 | Renovion Inc | Stable ascorbic acid compositions and methods of using the same |
| CN109169638A (zh) * | 2018-11-12 | 2019-01-11 | 苏州瑞徕生物科技有限公司 | 一种细胞保存液及其用途 |
| US12459820B2 (en) | 2020-06-11 | 2025-11-04 | J. W. Randolph Miller | Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy |
| KR20240131358A (ko) | 2022-01-04 | 2024-08-30 | 레노비온, 아이엔씨. | 글루타치온 염을 포함하는 수용액 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994022306A1 (en) * | 1993-04-06 | 1994-10-13 | Brigham And Womens Hospital | Nitric oxide combination therapy |
| WO1999037616A1 (en) * | 1998-01-22 | 1999-07-29 | Aenggaard Erik Emil | Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5570683A (en) | 1990-12-05 | 1996-11-05 | The General Hospital Corporation | Methods and devices for treating pulmonary vasoconstriction and asthma |
| DE69133584D1 (de) | 1990-12-05 | 2007-12-13 | Gen Hospital Corp | Vorrichtung zum Behandeln einen Lungengefässverengung und von Asthma |
| US5396882A (en) | 1992-03-11 | 1995-03-14 | The General Hospital Corporation | Generation of nitric oxide from air for medical uses |
| US5427797A (en) | 1993-04-06 | 1995-06-27 | Brigham And Women's Hospital | Systemic effects of nitric oxide inhalation |
| US5728705A (en) | 1993-10-04 | 1998-03-17 | The Trustees Of Columbia University In The City Of New York | Method of inducing vasorelaxation to treat pulmonary hypertension |
| US6063407A (en) * | 1995-02-16 | 2000-05-16 | The General Hospital Corporation | Treatment of vascular thrombosis and restenosis with inhaled nitric oxide |
| US5823180A (en) | 1995-04-03 | 1998-10-20 | The General Hospital Corporation | Methods for treating pulmonary vasoconstriction and asthma |
| WO1996039409A1 (en) * | 1995-06-05 | 1996-12-12 | Nitromed, Inc. | Nitrosylated and nitrated superoxide oxidants and reductants |
| DK0914103T3 (da) | 1996-04-05 | 2006-10-23 | Gen Hospital Corp | Behandling af hæmoglobinopati |
| SE9903985D0 (sv) * | 1999-11-03 | 1999-11-03 | Aga Ab | Use of nitric oxide |
| CN100486573C (zh) * | 1999-12-23 | 2009-05-13 | 硝化医药股份有限公司 | 硝基化的和亚硝基化的环加氧酶-2抑制剂、组合物及其用途 |
-
2000
- 2000-06-28 US US09/605,900 patent/US6601580B1/en not_active Expired - Lifetime
-
2001
- 2001-06-22 IL IL15370201A patent/IL153702A0/xx unknown
- 2001-06-22 AU AU2001273622A patent/AU2001273622B2/en not_active Ceased
- 2001-06-22 WO PCT/US2001/041102 patent/WO2002000175A2/en not_active Ceased
- 2001-06-22 CN CNB018118860A patent/CN100488497C/zh not_active Expired - Fee Related
- 2001-06-22 CA CA002414409A patent/CA2414409A1/en not_active Abandoned
- 2001-06-22 MX MXPA03000182A patent/MXPA03000182A/es not_active Application Discontinuation
- 2001-06-22 EP EP01952915A patent/EP1301076A4/en not_active Withdrawn
- 2001-06-22 AU AU7362201A patent/AU7362201A/xx active Pending
- 2001-06-22 KR KR1020027017893A patent/KR100849103B1/ko not_active Expired - Fee Related
- 2001-06-22 JP JP2002504958A patent/JP2004509850A/ja active Pending
-
2003
- 2003-06-09 US US10/458,578 patent/US6935334B2/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994022306A1 (en) * | 1993-04-06 | 1994-10-13 | Brigham And Womens Hospital | Nitric oxide combination therapy |
| WO1999037616A1 (en) * | 1998-01-22 | 1999-07-29 | Aenggaard Erik Emil | Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1301076A2 (en) | 2003-04-16 |
| US20030202969A1 (en) | 2003-10-30 |
| AU7362201A (en) | 2002-01-08 |
| CA2414409A1 (en) | 2002-01-03 |
| US6601580B1 (en) | 2003-08-05 |
| IL153702A0 (en) | 2003-07-06 |
| AU2001273622B2 (en) | 2007-05-10 |
| JP2004509850A (ja) | 2004-04-02 |
| US6935334B2 (en) | 2005-08-30 |
| CN1635923A (zh) | 2005-07-06 |
| MXPA03000182A (es) | 2004-02-26 |
| WO2002000175A2 (en) | 2002-01-03 |
| WO2002000175A3 (en) | 2002-08-15 |
| KR20030029530A (ko) | 2003-04-14 |
| CN100488497C (zh) | 2009-05-20 |
| EP1301076A4 (en) | 2004-09-22 |
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