KR100809569B1 - 무스카린 제제로서 벤즈이미다졸리디논 유도체 - Google Patents

무스카린 제제로서 벤즈이미다졸리디논 유도체 Download PDF

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KR100809569B1
KR100809569B1 KR1020067025160A KR20067025160A KR100809569B1 KR 100809569 B1 KR100809569 B1 KR 100809569B1 KR 1020067025160 A KR1020067025160 A KR 1020067025160A KR 20067025160 A KR20067025160 A KR 20067025160A KR 100809569 B1 KR100809569 B1 KR 100809569B1
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mmol
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alkyl
nmr
hydrogen
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KR20060130271A (ko
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니콜라스 마이클 켈리
크리스티앙 노룹 코흐
보-랑나르 톨프
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아카디아 파마슈티칼스 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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  • Psychiatry (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020067025160A 2001-10-02 2002-09-30 무스카린 제제로서 벤즈이미다졸리디논 유도체 Expired - Fee Related KR100809569B1 (ko)

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KR10-2004-7004720A Ceased KR20040047877A (ko) 2001-10-02 2002-09-30 무스카린 제제로서 벤즈이미다졸리디논 유도체

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US (6) US7087593B2 (https=)
EP (1) EP1432420B1 (https=)
JP (1) JP4347047B2 (https=)
KR (2) KR100809569B1 (https=)
CN (1) CN1561212A (https=)
AR (1) AR036716A1 (https=)
AT (1) ATE516030T1 (https=)
AU (1) AU2002327810B2 (https=)
BR (1) BR0213611A (https=)
CA (1) CA2457647A1 (https=)
MX (1) MXPA04003103A (https=)
NO (1) NO20041317L (https=)
NZ (1) NZ531550A (https=)
RU (1) RU2288919C2 (https=)
TW (1) TWI310034B (https=)
WO (1) WO2003028650A2 (https=)
ZA (1) ZA200402609B (https=)

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