KR100765039B1 - 사람의 오르판 g 단백질과 커플링된 수용체 - Google Patents
사람의 오르판 g 단백질과 커플링된 수용체 Download PDFInfo
- Publication number
- KR100765039B1 KR100765039B1 KR1020017006279A KR20017006279A KR100765039B1 KR 100765039 B1 KR100765039 B1 KR 100765039B1 KR 1020017006279 A KR1020017006279 A KR 1020017006279A KR 20017006279 A KR20017006279 A KR 20017006279A KR 100765039 B1 KR100765039 B1 KR 100765039B1
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- KR
- South Korea
- Prior art keywords
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (46)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10921398P | 1998-11-20 | 1998-11-20 | |
| US60/109,213 | 1998-11-20 | ||
| US12041699P | 1999-02-16 | 1999-02-16 | |
| US60/120,416 | 1999-02-16 | ||
| US12185299P | 1999-02-26 | 1999-02-26 | |
| US60/121,852 | 1999-02-26 | ||
| US12394999P | 1999-03-12 | 1999-03-12 | |
| US12394699P | 1999-03-12 | 1999-03-12 | |
| US60/123,949 | 1999-03-12 | ||
| US60/123,946 | 1999-03-12 | ||
| US13712799P | 1999-05-28 | 1999-05-28 | |
| US13643999P | 1999-05-28 | 1999-05-28 | |
| US13643799P | 1999-05-28 | 1999-05-28 | |
| US13643699P | 1999-05-28 | 1999-05-28 | |
| US13713199P | 1999-05-28 | 1999-05-28 | |
| US13656799P | 1999-05-28 | 1999-05-28 | |
| US60/136,439 | 1999-05-28 | ||
| US60/137,131 | 1999-05-28 | ||
| US60/136,436 | 1999-05-28 | ||
| US60/136,567 | 1999-05-28 | ||
| US60/136,437 | 1999-05-28 | ||
| US60/137,127 | 1999-05-28 | ||
| US14144899P | 1999-06-29 | 1999-06-29 | |
| US60/141,448 | 1999-06-29 | ||
| US15655599P | 1999-09-29 | 1999-09-29 | |
| US15663399P | 1999-09-29 | 1999-09-29 | |
| US15663499P | 1999-09-29 | 1999-09-29 | |
| US15665399P | 1999-09-29 | 1999-09-29 | |
| US60/156,653 | 1999-09-29 | ||
| US60/156,633 | 1999-09-29 | ||
| US60/156,634 | 1999-09-29 | ||
| US60/156,555 | 1999-09-29 | ||
| US15728099P | 1999-10-01 | 1999-10-01 | |
| US15729499P | 1999-10-01 | 1999-10-01 | |
| US15728299P | 1999-10-01 | 1999-10-01 | |
| US15729399P | 1999-10-01 | 1999-10-01 | |
| US15728199P | 1999-10-01 | 1999-10-01 | |
| US60/157,280 | 1999-10-01 | ||
| US60/157,282 | 1999-10-01 | ||
| US60/157,293 | 1999-10-01 | ||
| US60/157,294 | 1999-10-01 | ||
| US60/157,281 | 1999-10-01 | ||
| US41704499A | 1999-10-12 | 1999-10-12 | |
| US41676099A | 1999-10-12 | 1999-10-12 | |
| US09/416,760 | 1999-10-12 | ||
| US09/417,044 | 1999-10-12 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077018185A Division KR100926208B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010086040A KR20010086040A (ko) | 2001-09-07 |
| KR100765039B1 true KR100765039B1 (ko) | 2007-10-09 |
Family
ID=27586698
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077018185A Expired - Fee Related KR100926208B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020087024998A Withdrawn KR20080104062A (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020087003575A Expired - Fee Related KR100926209B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020087003578A Expired - Fee Related KR100963367B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020017006279A Expired - Fee Related KR100765039B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질과 커플링된 수용체 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077018185A Expired - Fee Related KR100926208B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020087024998A Withdrawn KR20080104062A (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020087003575A Expired - Fee Related KR100926209B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
| KR1020087003578A Expired - Fee Related KR100963367B1 (ko) | 1998-11-20 | 1999-10-13 | 사람의 오르판 g 단백질 커플링 수용체 |
Country Status (12)
| Country | Link |
|---|---|
| EP (8) | EP1849866B1 (cg-RX-API-DMAC7.html) |
| JP (5) | JP2003534767A (cg-RX-API-DMAC7.html) |
| KR (5) | KR100926208B1 (cg-RX-API-DMAC7.html) |
| AT (3) | ATE301673T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU770056B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2645717A1 (cg-RX-API-DMAC7.html) |
| DK (3) | DK1584683T3 (cg-RX-API-DMAC7.html) |
| ES (3) | ES2243095T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL142538A0 (cg-RX-API-DMAC7.html) |
| NZ (3) | NZ527622A (cg-RX-API-DMAC7.html) |
| PT (3) | PT1849866E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2000031258A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69938015T2 (de) | 1998-03-12 | 2009-01-15 | Astellas Pharma Inc. | Neue G Protein-gekoppelte Rezeptorproteine |
| US6071722A (en) * | 1998-04-24 | 2000-06-06 | Smithkline Beecham Corporation | Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1) |
| WO1999055733A1 (en) * | 1998-04-24 | 1999-11-04 | Smithkline Beecham Corporation | Cloning of a novel 7tm receptor axor-2 |
| EP1155031A4 (en) * | 1998-11-03 | 2002-11-27 | Smithkline Beecham Corp | G PROTEIN TORQUE RECEPTOR, SAID AXOR-14 |
| US7816492B2 (en) | 1998-11-20 | 2010-10-19 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors |
| USRE42190E1 (en) | 1998-11-20 | 2011-03-01 | Arena Pharmaceuticals, Inc. | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors |
| US20030017528A1 (en) | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| EP1157038A4 (en) * | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
| US6620615B1 (en) * | 1999-04-23 | 2003-09-16 | Curagen Corporation | G-protein coupled receptor—encoding nucleic acids |
| WO2000078809A1 (en) * | 1999-06-21 | 2000-12-28 | Smithkline Beecham Corporation | Axor16, a g protein coupled receptor |
| JP2003504054A (ja) * | 1999-07-13 | 2003-02-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | G−タンパク質共役型受容体およびそのdna配列 |
| CA2381437A1 (en) * | 1999-07-30 | 2001-02-08 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | G-protein coupled receptor and dna sequences thereof |
| CA2382889A1 (en) * | 1999-08-27 | 2001-03-08 | Takuya Watanabe | Novel g protein-coupled receptor protein and dna thereof |
| US6998255B1 (en) | 1999-09-24 | 2006-02-14 | Solvay Pharmaceuticals B.V. | Human G-protein coupled receptor |
| GB9923177D0 (en) * | 1999-09-30 | 1999-12-01 | Pfizer Ltd | Novel polypeptide |
| US6204017B1 (en) | 1999-10-07 | 2001-03-20 | Schering Corporation | Polynucleotide encoding a histamine receptor |
| GB9923890D0 (en) * | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9923893D0 (en) * | 1999-10-08 | 1999-12-08 | Pfizer Ltd | Novel polypeptide |
| GB9924956D0 (en) * | 1999-10-21 | 1999-12-22 | Pfizer Ltd | Novel polypeptide |
| GB9924960D0 (en) * | 1999-10-21 | 1999-12-22 | Pfizer Ltd | Novel polypeptide |
| EP1230361A2 (en) * | 1999-10-27 | 2002-08-14 | PHARMACIA & UPJOHN COMPANY | G protein-coupled receptors expressed in human brain |
| DE60036676T2 (de) * | 1999-10-29 | 2008-02-07 | Pfizer Inc. | G-protein-gekoppelte rezeptor-ähnliche proteine |
| WO2001032864A2 (en) * | 1999-11-03 | 2001-05-10 | Merck Patent Gmbh | Gpcr-kd5 polypeptides and dna sequences thereof |
| US6461836B1 (en) | 1999-11-05 | 2002-10-08 | Smithkline Beecham Corporation | Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof |
| AU784543B2 (en) * | 1999-11-16 | 2006-04-27 | Pharmacia & Upjohn Company | Novel G protein-coupled receptors |
| US7029857B1 (en) | 1999-12-17 | 2006-04-18 | H. Lundbeck A/S | Processes for obtaining compounds employing SNORF72 receptors |
| AU2398501A (en) * | 1999-12-20 | 2001-07-03 | Banyu Pharmaceutical Co., Ltd. | Novel guanosine triphosphate-binding protein-coupled receptor protein, bg26 |
| US6762029B2 (en) | 1999-12-23 | 2004-07-13 | Portola Pharmaceuticals, Inc. | Methods of identifying agents that modulate P2Y12 receptor activity |
| WO2001048189A1 (fr) * | 1999-12-28 | 2001-07-05 | Helix Research Institute | Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers |
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| US20030077709A1 (en) * | 2000-03-21 | 2003-04-24 | Masazumi Kamohara | Novel leukotriene B4 receptor |
| WO2001073021A1 (fr) * | 2000-03-28 | 2001-10-04 | Takeda Chemical Industries, Ltd. | Nouvelle proteine receptrice couplee a une proteine g et adn associe |
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| WO2012145361A1 (en) | 2011-04-19 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012145604A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012145603A1 (en) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| WO2012170702A1 (en) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
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