KR100745307B1 - 아미노퀴놀린 유도체 및 아데노신 ａ３ 리간드로서의 이의 용도 - Google Patents

아미노퀴놀린 유도체 및 아데노신 ａ３ 리간드로서의 이의 용도 Download PDF

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KR100745307B1
KR100745307B1 KR1020037015646A KR20037015646A KR100745307B1 KR 100745307 B1 KR100745307 B1 KR 100745307B1 KR 1020037015646 A KR1020037015646 A KR 1020037015646A KR 20037015646 A KR20037015646 A KR 20037015646A KR 100745307 B1 KR100745307 B1 KR 100745307B1
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branched
atom
cyano
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KR20040030648A (ko
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피터 아란이
라스즐로 발라즈스
마리아 발로프
임레 바타
산도르 바토리
라요스 티.나지
게자 티마리
킹아 보에르
올리비에르 피난세
졸탄 카푸이
엔드레 미쿠스
즈수즈산나 스자모스볼기
가보르 스제렉즈키
카탈린 우르반-스자보
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사노피-아벤티스
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Priority claimed from HU0102279A external-priority patent/HUP0102279A3/hu
Priority claimed from HU0200774A external-priority patent/HUP0200774A2/hu
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Neurosurgery (AREA)
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  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
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  • Immunology (AREA)
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  • Urology & Nephrology (AREA)
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  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
KR1020037015646A 2001-05-31 2002-05-29 아미노퀴놀린 유도체 및 아데노신 ａ３ 리간드로서의 이의 용도 Expired - Fee Related KR100745307B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
HU0102279A HUP0102279A3 (en) 2001-05-31 2001-05-31 A3 antagonist amino-quinoline-derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0102279 2001-05-31
HUP0200774 2002-03-01
HU0200774A HUP0200774A2 (hu) 2002-03-01 2002-03-01 Amino-piridin és amino-kinolin származékok, eljárás előállításukra, ezeket tartalmazó gyógyszerkészítmények és intermedierjeik
PCT/HU2002/000048 WO2002096879A1 (en) 2001-05-31 2002-05-29 Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands

Related Child Applications (1)

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KR1020077002737A Division KR20070020335A (ko) 2001-05-31 2002-05-29 아미노퀴놀린 유도체 및 아데노신 ａ３ 리간드로서의 이의용도

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KR20040030648A KR20040030648A (ko) 2004-04-09
KR100745307B1 true KR100745307B1 (ko) 2007-08-01

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US (1) US6969723B2 (enExample)
EP (1) EP1390349B1 (enExample)
JP (1) JP4409935B2 (enExample)
KR (1) KR100745307B1 (enExample)
CN (1) CN1257160C (enExample)
AR (1) AR036074A1 (enExample)
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Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
HUP0203976A3 (en) * 2002-11-15 2004-08-30 Sanofi Aventis Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
WO2004052291A2 (en) 2002-12-06 2004-06-24 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
RU2317290C2 (ru) * 2003-07-31 2008-02-20 Санофи-Авентис Производные аминохинолина и их применение в качестве лигандов аденозина а3
PL1663982T3 (pl) * 2003-07-31 2008-03-31 Sanofi Aventis Pochodne aminochinoliny i ich zastosowanie jako ligandów adenozyny A3
HUP0400812A2 (en) * 2004-04-19 2006-02-28 Sanofi Aventis Crystalline forms of 2-amino-3-cyano-quinoline derivatives, process for their preparation and pharmaceutical compositions containing them
WO2006040645A1 (en) * 2004-10-11 2006-04-20 Ranbaxy Laboratories Limited N-(3,5-dichloropyridin-4-yl)-2,4,5-alkoxy and 2,3,4-alkoxy benzamide derivatives as pde-iv (phophodiesterase type-iv) inhibitors for the treatment of inflammatory diseases such as asthma
HUP0402371A2 (en) * 2004-11-15 2006-09-28 Sanofi Aventis Novel 125-i-labeled amino-quinoline derivatives
KR100788161B1 (ko) * 2006-01-06 2007-12-21 (주)아모레퍼시픽 벤즈이미다졸 아민 유도체 또는 아미노퀴놀린 유도체를 함유하는 피부 미백용 조성물
HUP0700395A2 (en) * 2007-06-07 2009-03-02 Sanofi Aventis Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates
KR101106050B1 (ko) * 2009-03-25 2012-01-18 한국과학기술연구원 아미노퀴놀린 화합물, 이의 제조 방법 및 이를 함유하는 의약 조성물
WO2012030918A1 (en) * 2010-09-01 2012-03-08 Ambit Biosciences Corporation Adenosine a3 receptor modulating compounds and methods of use thereof
WO2012166654A1 (en) * 2011-05-27 2012-12-06 The Regents Of The University Of California Cyanoquinoline compounds having activity in correcting mutant-cftr processing and increasing ion transport and uses thereof
CA2754237A1 (en) 2011-05-27 2012-11-27 The Regents Of The University Of California Cyanoquinoline compounds having activity in correcting mutant-cftr processing and increasing ion transport and uses thereof
ES2578363B1 (es) 2015-01-22 2017-01-31 Palobiofarma, S.L. Moduladores de los receptores A3 de adenosina
CN108137547B (zh) 2015-08-03 2021-11-12 百时美施贵宝公司 可用作TNFα调节剂的杂环化合物

Citations (1)

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Publication number Priority date Publication date Assignee Title
JPH01180518A (ja) * 1988-01-12 1989-07-18 Nissan Chem Ind Ltd 配向処理剤

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IL111266A (en) * 1993-10-22 2002-03-10 Zeneca Ltd 2-HETEROARYL OR 2-ARYLPYRIDAZINO [4,5-b] QUINOLINE - 1, 10 - DIONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA2370264A1 (en) * 1999-04-23 2000-11-02 Takeda Chemical Industries, Ltd. 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
JPH01180518A (ja) * 1988-01-12 1989-07-18 Nissan Chem Ind Ltd 配向処理剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chemical abstracts, Vol. 116(25), 22.Jun.1992
유럽공개특허 제1180518호

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EA200301317A1 (ru) 2004-06-24
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WO2002096879A1 (en) 2002-12-05
EP1390349B1 (en) 2012-07-25
HRP20031091B1 (en) 2012-05-31
BR0209719A (pt) 2004-07-27
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IL158854A0 (en) 2004-05-12
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EP1390349A1 (en) 2004-02-25
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US20040186133A1 (en) 2004-09-23
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CA2448561A1 (en) 2002-12-05
US6969723B2 (en) 2005-11-29
MA26236A1 (fr) 2004-08-01
EE200300574A (et) 2004-02-16
CN1257160C (zh) 2006-05-24
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JP4409935B2 (ja) 2010-02-03
KR20040030648A (ko) 2004-04-09
PL366516A1 (en) 2005-02-07
NO20035300D0 (no) 2003-11-28
EA006854B1 (ru) 2006-04-28
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AU2002304358B2 (en) 2007-08-23
HRP20031091A2 (en) 2005-10-31
RS95003A (sr) 2007-02-05
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IS7052A (is) 2003-11-26
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