KR100668024B1 - 유방암, 난소암, 자궁내막암, 골수종 및 수막종 치료용 약제를 제조하기 위한 11베타-(4-아세틸페닐)-17베타-히드록시-17알파-(1,1,2,2,2-펜타플루오로에틸)에스트라-4,9-디엔-3-온의 용도 - Google Patents

유방암, 난소암, 자궁내막암, 골수종 및 수막종 치료용 약제를 제조하기 위한 11베타-(4-아세틸페닐)-17베타-히드록시-17알파-(1,1,2,2,2-펜타플루오로에틸)에스트라-4,9-디엔-3-온의 용도 Download PDF

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Publication number
KR100668024B1
KR100668024B1 KR1020037005360A KR20037005360A KR100668024B1 KR 100668024 B1 KR100668024 B1 KR 100668024B1 KR 1020037005360 A KR1020037005360 A KR 1020037005360A KR 20037005360 A KR20037005360 A KR 20037005360A KR 100668024 B1 KR100668024 B1 KR 100668024B1
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South Korea
Prior art keywords
antiprogestin
cancer
breast cancer
treatment
cell
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020037005360A
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English (en)
Korean (ko)
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KR20030057540A (ko
Inventor
옌스 호프만
로제마리 리흐트너
게르하르트 지마이스터
마르틴 슈나이더
울리케 푸르만
Original Assignee
쉐링 악티엔게젤샤프트
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Publication of KR20030057540A publication Critical patent/KR20030057540A/ko
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Publication of KR100668024B1 publication Critical patent/KR100668024B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020037005360A 2000-10-18 2001-10-17 유방암, 난소암, 자궁내막암, 골수종 및 수막종 치료용 약제를 제조하기 위한 11베타-(4-아세틸페닐)-17베타-히드록시-17알파-(1,1,2,2,2-펜타플루오로에틸)에스트라-4,9-디엔-3-온의 용도 Expired - Fee Related KR100668024B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24099100P 2000-10-18 2000-10-18
EP00250342.3 2000-10-18
EP00250342 2000-10-18
US60/240,991 2000-10-18
PCT/EP2001/012006 WO2002032432A1 (en) 2000-10-18 2001-10-17 Use of antiprogestins for the induction of apoptosis in a cell

Publications (2)

Publication Number Publication Date
KR20030057540A KR20030057540A (ko) 2003-07-04
KR100668024B1 true KR100668024B1 (ko) 2007-01-15

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Family Applications (1)

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KR1020037005360A Expired - Fee Related KR100668024B1 (ko) 2000-10-18 2001-10-17 유방암, 난소암, 자궁내막암, 골수종 및 수막종 치료용 약제를 제조하기 위한 11베타-(4-아세틸페닐)-17베타-히드록시-17알파-(1,1,2,2,2-펜타플루오로에틸)에스트라-4,9-디엔-3-온의 용도

Country Status (28)

Country Link
EP (1) EP1326617B9 (enExample)
JP (1) JP2004511523A (enExample)
KR (1) KR100668024B1 (enExample)
CN (1) CN1209111C (enExample)
AT (1) ATE334683T1 (enExample)
AU (2) AU2361902A (enExample)
BG (1) BG107744A (enExample)
BR (1) BR0114696A (enExample)
CA (1) CA2423020C (enExample)
CY (1) CY1105745T1 (enExample)
CZ (1) CZ299823B6 (enExample)
DE (1) DE60121980T2 (enExample)
DK (1) DK1326617T3 (enExample)
EA (1) EA010593B1 (enExample)
EE (1) EE200300157A (enExample)
ES (1) ES2269492T3 (enExample)
HR (1) HRP20030388A2 (enExample)
HU (1) HUP0301433A3 (enExample)
IL (2) IL154976A0 (enExample)
MX (1) MXPA03002955A (enExample)
NO (1) NO20031741L (enExample)
NZ (1) NZ538347A (enExample)
PL (1) PL360157A1 (enExample)
PT (1) PT1326617E (enExample)
SI (1) SI1326617T1 (enExample)
SK (1) SK4702003A3 (enExample)
UA (1) UA76729C2 (enExample)
WO (1) WO2002032432A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
CA2683517A1 (en) * 2007-04-23 2008-10-30 Bayer Schering Pharma Aktiengesellschaft Combination of progesterone-receptor antagonist together with a lutein-hormone-releasing hormone agonist and antagonist for use in brca mediated diseases
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
CA2683809A1 (en) * 2007-04-23 2008-10-30 Bayer Schering Pharma Aktiengesellschaft Progesterone-receptor antagonist for use in brca alone or as combination with antiestrogen
GB0718167D0 (en) 2007-09-18 2007-10-31 Cancer Rec Tech Ltd Cancer marker and therapeutic target
AU2012318618B2 (en) * 2011-10-04 2017-01-12 Invivis Pharmaceuticals Inc. Methods and systems for identifying and treating anti-progestin sensitive tumors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
UA76729C2 (uk) 2006-09-15
EE200300157A (et) 2003-08-15
JP2004511523A (ja) 2004-04-15
EA200300479A1 (ru) 2003-10-30
ATE334683T1 (de) 2006-08-15
NO20031741L (no) 2003-06-17
SK4702003A3 (en) 2004-01-08
EA010593B1 (ru) 2008-10-30
KR20030057540A (ko) 2003-07-04
MXPA03002955A (es) 2003-08-07
HRP20030388A2 (en) 2005-04-30
CA2423020A1 (en) 2002-04-25
EP1326617B9 (en) 2006-10-25
CA2423020C (en) 2009-01-20
AU2002223619B2 (en) 2006-08-24
SI1326617T1 (sl) 2007-02-28
DE60121980T2 (de) 2007-03-01
NO20031741D0 (no) 2003-04-15
BG107744A (bg) 2004-02-27
CN1469749A (zh) 2004-01-21
HK1062273A1 (en) 2004-10-29
IL154976A (en) 2007-05-15
CZ299823B6 (cs) 2008-12-03
AU2361902A (en) 2002-04-29
PT1326617E (pt) 2006-12-29
IL154976A0 (en) 2003-10-31
BR0114696A (pt) 2003-11-18
DE60121980D1 (de) 2006-09-14
ES2269492T3 (es) 2007-04-01
PL360157A1 (en) 2004-09-06
NZ538347A (en) 2007-03-30
WO2002032432A1 (en) 2002-04-25
HUP0301433A2 (hu) 2003-10-28
EP1326617B1 (en) 2006-08-02
CN1209111C (zh) 2005-07-06
HUP0301433A3 (en) 2010-01-28
CY1105745T1 (el) 2010-12-22
EP1326617A1 (en) 2003-07-16
DK1326617T3 (da) 2006-12-18

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