KR100536420B1 - 2-할로-6-ｏ-치환된 케토라이드 유도체 및 이를 포함하는 약제학적 조성물 - Google Patents

2-할로-6-ｏ-치환된 케토라이드 유도체 및 이를 포함하는 약제학적 조성물 Download PDF

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Publication number
KR100536420B1
KR100536420B1 KR10-2000-7004613A KR20007004613A KR100536420B1 KR 100536420 B1 KR100536420 B1 KR 100536420B1 KR 20007004613 A KR20007004613 A KR 20007004613A KR 100536420 B1 KR100536420 B1 KR 100536420B1
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South Korea
Prior art keywords
compound
formula
quinolinyl
substituted
hydrogen
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Expired - Fee Related
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KR10-2000-7004613A
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English (en)
Korean (ko)
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KR20010015793A (ko
Inventor
판리탐
오르야트선
츄다니엘티
플라트너제이콥제이
첸얀
클라크리차드에프
Original Assignee
아보트 러보러터리즈
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
KR10-2000-7004613A 1997-10-29 1998-10-29 2-할로-6-ｏ-치환된 케토라이드 유도체 및 이를 포함하는 약제학적 조성물 Expired - Fee Related KR100536420B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95988197A 1997-10-29 1997-10-29
US08/959,881 1997-10-29
US15423998A 1998-09-16 1998-09-16
US09/154,239 1998-09-16
PCT/US1998/022989 WO1999021871A1 (en) 1997-10-29 1998-10-29 2-halo-6-o-substituted ketolide derivatives

Publications (2)

Publication Number Publication Date
KR20010015793A KR20010015793A (ko) 2001-02-26
KR100536420B1 true KR100536420B1 (ko) 2005-12-16

Family

ID=26851273

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2000-7004613A Expired - Fee Related KR100536420B1 (ko) 1997-10-29 1998-10-29 2-할로-6-ｏ-치환된 케토라이드 유도체 및 이를 포함하는 약제학적 조성물

Country Status (24)

Country Link
EP (1) EP1027362B1 (https=)
JP (1) JP2001521039A (https=)
KR (1) KR100536420B1 (https=)
CN (1) CN1240707C (https=)
AR (1) AR015994A1 (https=)
AT (1) ATE298760T1 (https=)
AU (1) AU751448B2 (https=)
BG (1) BG64707B1 (https=)
BR (1) BR9813319A (https=)
CA (1) CA2307788C (https=)
CO (1) CO4990960A1 (https=)
CZ (1) CZ300063B6 (https=)
DE (1) DE69830739T2 (https=)
DK (1) DK1027362T3 (https=)
ES (1) ES2244094T3 (https=)
HU (1) HUP0004282A3 (https=)
IL (1) IL135519A0 (https=)
NO (1) NO20002190L (https=)
NZ (1) NZ503822A (https=)
PL (1) PL191453B1 (https=)
PT (1) PT1027362E (https=)
SK (1) SK286397B6 (https=)
TR (1) TR200001142T2 (https=)
WO (1) WO1999021871A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39743E1 (en) * 1998-10-15 2007-07-24 Aventis Pharma S.A. 2-halogenated derivatives of 5-0 desosaminyl-erythronolide a, their preparation process and their antibiotic use
FR2784682B1 (fr) 1998-10-15 2002-12-06 Hoechst Marion Roussel Inc Nouveaux derives 2-halogene de 5-0-desosaminylerythronolide a, leur procede de preparation et leur application comme medicaments
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
ID30547A (id) * 1999-04-16 2001-12-20 Kosan Biosciences Inc Zat anti-infeksi makrolida
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6569836B2 (en) 1999-12-02 2003-05-27 Abbott Laboratories 6-O-alkyl-2-nor-2-substituted ketolide derivatives
JP2003527347A (ja) * 1999-12-02 2003-09-16 アボット・ラボラトリーズ ６−ｏ−アルキル−２−ノル−２−置換ケトリド誘導体
JP2001261694A (ja) 2000-03-06 2001-09-26 Pfizer Prod Inc ケトライド抗生物質
US6605707B1 (en) 2000-03-23 2003-08-12 Abbott Laboratories Process for the preparation of 6-O-propargyl erythromycin derivatives
DE60104240T2 (de) 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika
US6472372B1 (en) 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
WO2003024986A1 (en) 2001-09-17 2003-03-27 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
NZ533282A (en) 2001-12-05 2006-09-29 Ortho Mcneil Pharm Inc 6-O-Acyl ketolide derivatives of erythromycine useful as antibacterials
JP2005522453A (ja) * 2002-02-13 2005-07-28 アボット・ラボラトリーズ マクロライド抗菌化合物
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
JP2005528409A (ja) * 2002-04-25 2005-09-22 アボット・ラボラトリーズ オキソリド抗菌薬
WO2004078771A1 (ja) * 2003-03-07 2004-09-16 Taisho Pharmaceutical Co., Ltd. ２－フルオロ－６－ｏ－置換ケトライド誘導体
JP2007254285A (ja) * 2004-03-16 2007-10-04 Taisho Pharmaceut Co Ltd ２−フルオロ−６−ｏ−置換ケトライド誘導体
BRPI1011959A2 (pt) * 2009-05-27 2016-04-26 Wockhardt Research Center compostos de cetolídeo tendo atividade antimicrobiana.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444051A (en) * 1990-11-21 1995-08-22 Roussel Uclaf Erythromycin compounds
US5747467A (en) * 1995-12-22 1998-05-05 Roussel Uclaf Erythromycins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8506380D0 (en) * 1985-03-12 1985-04-11 Beecham Group Plc Chemical compounds
ATE135707T1 (de) * 1992-04-22 1996-04-15 Taisho Pharmaceutical Co Ltd 5-0-desosaminylerythronolid a derivate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444051A (en) * 1990-11-21 1995-08-22 Roussel Uclaf Erythromycin compounds
US5747467A (en) * 1995-12-22 1998-05-05 Roussel Uclaf Erythromycins

Also Published As

Publication number Publication date
AR015994A1 (es) 2001-05-30
EP1027362B1 (en) 2005-06-29
IL135519A0 (en) 2001-05-20
WO1999021871A1 (en) 1999-05-06
ATE298760T1 (de) 2005-07-15
HK1031383A1 (en) 2001-06-15
DE69830739T2 (de) 2006-04-20
DE69830739D1 (de) 2005-08-04
SK6332000A3 (en) 2000-09-12
NO20002190D0 (no) 2000-04-27
CZ20001525A3 (cs) 2000-10-11
JP2001521039A (ja) 2001-11-06
CN1240707C (zh) 2006-02-08
HUP0004282A2 (hu) 2001-04-28
BG64707B1 (bg) 2005-12-30
NO20002190L (no) 2000-06-29
KR20010015793A (ko) 2001-02-26
CA2307788A1 (en) 1999-05-06
CA2307788C (en) 2008-05-20
SK286397B6 (sk) 2008-09-05
ES2244094T3 (es) 2005-12-01
HUP0004282A3 (en) 2001-10-29
NZ503822A (en) 2002-12-20
PL191453B1 (pl) 2006-05-31
BR9813319A (pt) 2000-08-22
EP1027362A1 (en) 2000-08-16
CO4990960A1 (es) 2000-12-26
TR200001142T2 (tr) 2000-09-21
CN1283199A (zh) 2001-02-07
AU1288199A (en) 1999-05-17
AU751448B2 (en) 2002-08-15
PT1027362E (pt) 2005-08-31
BG104434A (en) 2001-01-31
DK1027362T3 (da) 2005-10-31
PL340290A1 (en) 2001-01-29
CZ300063B6 (cs) 2009-01-21

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