KR100518060B1 - 마이크로믹서 - Google Patents

마이크로믹서 Download PDF

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Publication number
KR100518060B1
KR100518060B1 KR10-2000-7004186A KR20007004186A KR100518060B1 KR 100518060 B1 KR100518060 B1 KR 100518060B1 KR 20007004186 A KR20007004186 A KR 20007004186A KR 100518060 B1 KR100518060 B1 KR 100518060B1
Authority
KR
South Korea
Prior art keywords
micromixer
passage
grooves
housing
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR10-2000-7004186A
Other languages
English (en)
Korean (ko)
Other versions
KR20010024538A (ko
Inventor
쿠프울리히
슈멜츠미카엘
바이라우안드레아스
Original Assignee
메르크 파텐트 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by 메르크 파텐트 게엠베하 filed Critical 메르크 파텐트 게엠베하
Publication of KR20010024538A publication Critical patent/KR20010024538A/ko
Application granted granted Critical
Publication of KR100518060B1 publication Critical patent/KR100518060B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40Static mixers
    • B01F25/42Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/432Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/10Mixing gases with gases
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/47Mixing liquids with liquids; Emulsifying involving high-viscosity liquids, e.g. asphalt
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00783Laminate assemblies, i.e. the reactor comprising a stack of plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00819Materials of construction
    • B01J2219/00824Ceramic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00819Materials of construction
    • B01J2219/00831Glass
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00819Materials of construction
    • B01J2219/00833Plastic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00873Heat exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00889Mixing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00891Feeding or evacuation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
KR10-2000-7004186A 1997-10-22 1998-10-12 마이크로믹서 Expired - Fee Related KR100518060B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19746583.8 1997-10-22
DE19746583A DE19746583A1 (de) 1997-10-22 1997-10-22 Mikromischer
PCT/EP1998/006462 WO1999020379A1 (de) 1997-10-22 1998-10-12 Mikromischer

Publications (2)

Publication Number Publication Date
KR20010024538A KR20010024538A (ko) 2001-03-26
KR100518060B1 true KR100518060B1 (ko) 2005-09-28

Family

ID=7846245

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2000-7004186A Expired - Fee Related KR100518060B1 (ko) 1997-10-22 1998-10-12 마이크로믹서

Country Status (6)

Country Link
US (1) US6457854B1 (enExample)
EP (1) EP1047489B1 (enExample)
JP (1) JP2001520112A (enExample)
KR (1) KR100518060B1 (enExample)
DE (2) DE19746583A1 (enExample)
WO (1) WO1999020379A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100898065B1 (ko) 2007-10-19 2009-05-15 송상섭 마이크로 리액터
KR101176175B1 (ko) 2010-07-30 2013-05-09 광주과학기술원 마이크로 믹서 및 이의 제조 방법
TWI705850B (zh) * 2018-06-21 2020-10-01 大陸商中微半導體設備(上海)股份有限公司 耐腐蝕的氣體混合裝置及等離子處理設備

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US6105880A (en) * 1998-01-16 2000-08-22 The Sherwin-Williams Company Mixing block for mixing multi-component reactive material coating systems and an apparatus using same
DE29903296U1 (de) * 1999-02-24 2000-08-03 CPC Cellular Process Chemistry GmbH, 60386 Frankfurt Mikroreaktor
DE19911776A1 (de) 1999-03-17 2000-09-21 Merck Patent Gmbh Verpackungssysteme für kosmetische Formulierungen
DE19911777A1 (de) * 1999-03-17 2000-09-21 Merck Patent Gmbh Verfahren zur Herstellung von kosmetischen Formulierungen
GB2355543A (en) * 1999-10-20 2001-04-25 Univ Sheffield Fluidic flow control and fluidic device
DE10001317A1 (de) * 2000-01-14 2001-07-19 Merck Patent Gmbh Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien
US7905653B2 (en) * 2001-07-31 2011-03-15 Mega Fluid Systems, Inc. Method and apparatus for blending process materials
DE10159985B4 (de) * 2001-12-06 2008-02-28 Schwesinger, Norbert, Prof.Dr.-Ing. Mikroemulgator
DE10218280C1 (de) * 2002-04-19 2003-11-20 Fraunhofer Ges Forschung Integriertes Misch- und Schaltsystem für die Mikroreaktionstechnik
AU2003249301A1 (en) * 2002-07-16 2004-02-02 Mixtek System, Llc Aerosol mixing system with columns
KR100472058B1 (ko) * 2002-11-02 2005-03-11 한국전자통신연구원 미소유체 혼합을 위한 미소 유체제어 소자
DE10254534A1 (de) * 2002-11-22 2004-06-09 Henkel Kgaa Vorrichtung zum Vermischen von wenigstens zwei Flüssigkeiten
US7094354B2 (en) 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7125711B2 (en) 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7485671B2 (en) * 2003-05-16 2009-02-03 Velocys, Inc. Process for forming an emulsion using microchannel process technology
EP1633463B1 (en) * 2003-05-16 2007-10-24 Velocys Inc. Process for forming an emulsion using microchannel process technology
US7435381B2 (en) 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
DE10333924B3 (de) 2003-07-25 2004-10-07 Wella Ag Mehrkomponentenverpackung, Mischverfahren und Verwendung von statischen Mikromischern
US7347617B2 (en) 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
JP4581380B2 (ja) * 2003-11-17 2010-11-17 パナソニック株式会社 核酸増幅反応容器およびその製造方法
TWI230683B (en) * 2004-04-19 2005-04-11 Jing-Tang Yang The micromixer with overlapping-crisscross entrance
KR100658361B1 (ko) * 2005-09-12 2006-12-15 주식회사 스펙 마이크로 채널 리액터
DE102005012415B4 (de) * 2005-03-17 2006-12-28 Syntics Gmbh Verfahrenstechnisches Funktionselement aus einem Folienstapel
US7314060B2 (en) * 2005-04-23 2008-01-01 Industrial Technology Research Institute Fluid flow conducting module
US20060280029A1 (en) * 2005-06-13 2006-12-14 President And Fellows Of Harvard College Microfluidic mixer
US20060285433A1 (en) * 2005-06-20 2006-12-21 Jing-Tang Yang Fluidic mixer of serpentine channel incorporated with staggered sudden-expansion and convergent cross sections
US20070047388A1 (en) * 2005-08-25 2007-03-01 Rockwell Scientific Licensing, Llc Fluidic mixing structure, method for fabricating same, and mixing method
DE102005060280B4 (de) * 2005-12-16 2018-12-27 Ehrfeld Mikrotechnik Bts Gmbh Integrierbarer Mikromischer sowie dessen Verwendung
JP4931065B2 (ja) * 2007-03-29 2012-05-16 財団法人 岡山県産業振興財団 衝突型マイクロミキサー
KR101113727B1 (ko) * 2008-02-18 2012-02-27 주식회사 올메디쿠스 수직 적층식 마이크로 믹서 및 그 제조방법
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CN105056821B (zh) * 2015-08-17 2017-05-03 江苏大学 一种对称椭圆弧挡板的十字微混合器
US10076730B2 (en) 2016-01-06 2018-09-18 The University Of British Columbia Bifurcating mixers and methods of their use and manufacture
KR101736797B1 (ko) * 2016-01-29 2017-05-17 인하대학교 산학협력단 미세 유체 혼합기
CN105771765B (zh) * 2016-03-30 2018-02-27 江苏大学 一种内置周期性阻块和挡板的被动式微混合器
CN106268471B (zh) * 2016-08-05 2019-02-05 江苏大学 一种渐缩弯管串联式微混合器
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CN109092225B (zh) * 2018-11-02 2024-06-07 南京正源搪瓷设备制造有限公司 红心k型微反应器
CN109647307A (zh) * 2019-01-28 2019-04-19 北京理工大学 Y型组合式微通道结构
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100898065B1 (ko) 2007-10-19 2009-05-15 송상섭 마이크로 리액터
KR101176175B1 (ko) 2010-07-30 2013-05-09 광주과학기술원 마이크로 믹서 및 이의 제조 방법
TWI705850B (zh) * 2018-06-21 2020-10-01 大陸商中微半導體設備(上海)股份有限公司 耐腐蝕的氣體混合裝置及等離子處理設備

Also Published As

Publication number Publication date
JP2001520112A (ja) 2001-10-30
KR20010024538A (ko) 2001-03-26
DE19746583A1 (de) 1999-04-29
DE59805556D1 (de) 2002-10-17
EP1047489B1 (de) 2002-09-11
US6457854B1 (en) 2002-10-01
WO1999020379A1 (de) 1999-04-29
EP1047489A1 (en) 2000-11-02

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