KR100512690B1 - Cosmetic composition containing bletilla striata and leontopodium alpinum extract - Google Patents

Abstract

The present invention relates to a cosmetic composition comprising 1 to 30% by weight of the grown and edelweiss complex extract with respect to the total weight of the composition, according to the present invention, the skin moisturizing effect, antibacterial effect against dermatophytes, damaged skin It is possible to obtain a cosmetic composition containing the overgrown and edelweiss composite extract, which is very effective in improving the recovery rate.

Description

Cosmetic composition containing overgrown and edelweiss extract {COSMETIC COMPOSITION CONTAINING BLETILLA STRIATA AND LEONTOPODIUM ALPINUM EXTRACT}

The present invention relates to a cosmetic composition having a skin moisturizing, antibacterial and damaged skin recovery effect, and more specifically, by containing the grown and edelweiss extract to improve the skin moisturizing effect, antibacterial effect on the skin flora, damaged skin recovery speed It relates to a skin cosmetic composition having.

Jalan ( Bletilla striata Relchb.fil ) is an oriental orchid belonging to the orchid family Orchidaceae of the monocotyledonous plants that naturally grows in Korea. It mainly breeds in Haenam, Jindal, Yudalsan, Jeonnam, and its size is about 50cm, and the stem is shortened to round round roots. The leaves are 20-30cm long, 2-5cm wide, long oval, pointed at the end, narrowed at the bottom, and shaped like a leaf house with many vertical wrinkles.

These eggs are commonly used as astringents, hemostatic agents, and drainage agents in wounds and stomach ulcers. In China, it is used to treat heartburn, cough, and shortness of breath. It also has mucus and makes grass.

In addition, it acts on menopause, is known to be used to protect the lungs, bleeding due to keratosis, nosebleeds, trauma, carbuncles, spears, burns, and limbs. Always use the powder alone, glutinous rice or hot water to cool and have a certain treatment effect. It is also known to be used in combination with a corresponding drug depending on the symptoms (Korean Patent Application No. 2001-0072279; Herbal Book, Kyohaksa, 1999, 501P).

On the other hand, edelweiss ( Gnaphali㎛ leontopodi㎛ ) is an alpine plant of perennial plant of the dicotyledonaceae Campanaceae , 10-20cm high, and covered with white wool. The leaves are relatively large in the roots, slightly on the stems, and linear. Poins are gathered at the end of stem and spread all around, with a little headpiece in the center. Edelweiss grows well in dry places and is distributed in Europe, Siberia, the Himalayas, China, Korea, Japan and Sakhalin, but not in the polar regions. Cosmetically, there are many flavonoids such as luteolin and luteolin-7-glucoside, which have skin soothing effect and antioxidant activity. They absorb ultraviolet rays and protect the skin from reaching ultraviolet rays.

Conventional techniques for overgrowing include extracting a mixture ( Gleditsia japonica Miq ,) horseback riding ( Cimicifuga heracleifolia Kom ), white matter ( Bletilla striata ) and fruit root ( Trichosanthes kirilowii Max ) to produce a cosmetic with excellent whitening effect. Patent Application Publication No. 2001-0106527), Twelve herbal medicines of white paper, white weight, deity, passerby, baekryeom, baekbuja, bokyeong, baekchul, shinyi, baekgangjam, earthenware and yulmu (3: 2: 2: 1: 1: 1 (1: 1: 1: 1: 3: 3) to improve skin blemishes, acne, and aging (Korean Patent Application Publication No. 2000-0075193).

The inventors of the present invention have been steadily experimenting to find a substance that can increase its effectiveness as the extract is known to moisturize, regenerate, and improve the inflammatory effect, the synergistic effect of extracting the grown and edelweis together It was found that large, the present invention was completed.

Accordingly, an object of the present invention is to obtain a cosmetic composition having excellent skin moisturizing effect, antibacterial effect on skin flora, and improvement of recovery rate of damaged skin by using the grown and edelweiss complex extract.

According to the present invention in order to achieve the above object, there is provided a cosmetic composition, characterized in that containing 1 to 30% by weight relative to the total weight of the composition and grown edelweiss extract.

Hereinafter, the present invention will be described in detail.

To obtain the overgrown extract, the root of the overgrown is used, and to obtain the edelweiss extract, the leaves and flowers of the edelweiss can be used.

The overgrown and edelweiss extracts can be obtained by mixing the overgrown and edelweiss or by separately extracting the overgrown and edelweiss.

It is preferable to mix the grown and edelweiss in a weight ratio of 9: 1 to 6: 4 based on the dry raw material. In such a ratio, moisturizing and inflammation improvement are shown evenly, and maximum synergistic effect is obtained.

As the extraction solvent, alcohols such as methanol, isopropyl alcohol, propylene glycol, ethanol, purified water and the like can be used. Among them, it is particularly preferable to use 1,3-butylene glycol having an antiseptic effect and minimizing the loss of physical properties and polysaccharides.

At this time, it is preferable from the viewpoint of extraction efficiency that the ratio of the dry raw material and the extraction solvent is a weight ratio of 1: 4 to 1: 9.

This extraction is carried out for 3 to 48 hours at 40 ~ 80 ℃ by adding an extraction solvent to the raw material in the above ratio, it is filtered to remove the insoluble matter. In addition, activated carbon or the like can be used to remove color and off-flavor from conventional methods.

These grown, edelweiss mixture extract is significantly higher than the skin moisturizing effect, antibacterial effect on the skin flora, and the effect of improving the recovery rate of damaged skin than when the extract was used alone.

The grown and edelweiss complex extract is added in an amount of 1.0 to 30% by weight based on the total weight of the cosmetic composition. The addition of less than 1.0% by weight is ineffective, the addition of more than 30% by weight affects safety and stability, increases the cost, and obtains a conventional cosmetic composition in view of the characteristics of the cosmetics should contain other ingredients Since it is difficult, it is preferable to add 1.0-30 weight%.

The cosmetic composition is not particularly limited in its formulation. That is, formulations such as skin adhesives and transdermal dosage forms such as lotion, cream, pack, gel, lotion, and spray are possible.

Example

(Comparative Example 1)

Naturally dried edelweiss leaves and flowers were pulverized and 90 g of purified water was added to 10 g of the pulverized product, followed by extraction at 80 ° C. for 48 hours, and filtered through 250 mesh to obtain 80 g of an extract.

(Comparative Example 2)

The roots of the well-washed eggs were washed with clean purified water and dried for 24 hours at 50 ° C. 360 g of 1,3-butylene glycol was added to 90 g of the pulverized powder, which was extracted at 60 ° C. for 3 hours, and filtered through 250 mesh. After filtration using 0.5 μm filter paper again, the mixture was stirred with activated carbon for 2 hours to remove color and odor. It filtered again using 0.3-0.2 micrometer filter paper and obtained about 420g of extracts.

(Example 1)

The extracts of Comparative Example 1 and Comparative Example 2 were mixed to obtain about 500 g of bred and Edelweiss composite extract.

(Example 2)

10 g of naturally dried edelweiss leaves and flowers were mixed with 90 g of crushed root crushed by washing with purified water and dried at 50 ° C. for 24 hours, and 430 g of 1,3-butylene glycol was added to the mixture. After that, the extract was extracted at 60 ° C. for 3 hours and filtered through 250 mesh. After filtration using 0.5 μm filter paper again, the mixture was stirred with activated carbon for 2 hours to remove color and odor. It filtered again using 0.3-0.2 micrometer filter paper, and obtained about 500 g of extract.

 (Example 3)

The dried roots washed with clean purified water were shaken off and dried at 50 ° C. for 24 hours. 360 g of 1,3-butylene glycol was added to 90 g of the pulverized powder, and 80 g of the edelweiss extract obtained in Comparative Example 1 was put together, extracted at 60 ° C. for 3 hours, and filtered through 250 mesh. After filtration using 0.5 μm filter paper again, the mixture was stirred with activated carbon for 2 hours to remove color and odor. It filtered again using 0.3-0.2 micrometer filter paper, and obtained about 500 g of extract.

(Production Examples 1 to 3 and Comparative Production Examples 1 and 2)

As shown in Table 1 below, the raw materials of each phase were weighed and then melted. Subsequently, the virtual phase was thoroughly mixed with the spiral phase, and then the skin lotion was prepared by slowly adding the polyphase while rotating the stirrer at 1000-2000 rpm.

(Test Example 1)

Human body patch test

Human patch test was performed to determine the skin irritation of the extracts.

1,3-butylene glycol and purified water were patched for 24 hours in Examples 1 to 3, Comparative Examples 1 and 2, and control water, respectively, on the upper arm region of 30 healthy women. Subsequently, it was removed and skin irritation measured, and skin irritation was measured again after 24 hours and 48 hours.

Criterion and skin irritation calculation formula of the skin irritation is as follows, the results are shown in Table 2 below.

Criteria-: No erythema or unusual phenomenon

          +-: Slightly reddish

          +: Significantly redder than the surroundings

          ++: Severe reddening and swelling around

According to Table 2, the complex extract according to the present invention was found to have less skin irritation.

(Test Example 2)

Skin moisturizing effect

Twenty five healthy women (mean age 29.5 years) at 22 ~ 24 ℃, 55% relative humidity and no air flow were divided into 5 groups. Preparation Examples 1 to 3 and Comparative Preparation Examples 1 and 2 were applied twice a day for 6 weeks to the entire face centered around the eyes of each group. By using Skicon-200 (IBS Co. Japan), the moisture content of the cheek area was measured before the test and 6 weeks after application to measure the persistence of the moisturizing effect. The results are shown in Table 3 as an average value for each test group.

Improvement = (6 weeks after application-before test) / before test x 100

As can be seen in Table 3, when the extract and the edelweis complex extraction can be seen that the improvement is much better.

(Test Example 3)

Antibacterial effect test on skin flora

In order to confirm the growth inhibitory effect of the skin flora of the complex extract of the present invention, the complex extract obtained in Examples 1 to 3 and the extracts obtained in Comparative Examples 1 and 2 and the control was tested with purified water.

Tryptic soy agar (TSA); Difco co.} Was plated on a solid flat agar plate with 1 × 10 ⁷ ea / ml of each bacterium, and a 5 mm disc was placed in the center of the plate. Then, 20 μl of Example and Comparative Example extracts and control were dropped thereon. Dried. After natural drying, the cells were incubated at 37 ° C for 24 hours to determine the presence or absence of transparent low-ring rings.

The results are shown in Table 4 below.

-: Can't create low ring

+-: Strain growth after formation of low ring

+: Create a weak low ring

++: create strong low ring

+++: very strong low ring generation

According to Table 4, the complex extract according to the present invention was excellent in the antibacterial effect against the skin flora.

(Test Example 4)

Experiment to improve the recovery speed of damaged skin

In order to evaluate the effect of improving the recovery rate of the damaged skin of the grown and edelweiss complex extract, it was evaluated using the formulations obtained in Preparation Examples 1 to 3 and the formulations obtained in Comparative Preparation Examples 1 and 2.

The experimental method and procedure were used by modifying the paper (Walter Wigger-Alberti et al. J Am Acad Dermatol. 1999) that examined the effect of protective creams on irritants. The specific experimental methods were as follows.

Twenty healthy men and women (10 males, 10 females: average age 28.2 years) were treated with 0.03ml of 10% sodium lauryl sulfate (irritant), a pin chamber (diameter 12 mm), Epitest Ltd Oy. Finland) for 30 minutes and then removed. After 24 hours of removal, the degree of irritation was evaluated through visual observation, and then, Preparation Examples 1 to 3 and Comparative Preparation Examples 1 and 2 were applied twice a day for 3 weeks.

All the above experiments were carried out at the same place with a temperature of 22 ± 2 ℃, relative humidity 55-60%.

Visual observation: Visual Score

The evaluation method was divided into six grades as follows. The evaluation results are shown in Table 5 below.

0: no reaction

1: very slight erythema

2: slight erythema

3: erythema, border edema, papule

4: erythema, edema

5: severe erythema, edema, blisters

As can be seen from the results of Table 5, it can be seen that the skin lotion containing the grown and edelweiss complex extract of the present invention has an excellent ability to improve damaged skin as compared to the skin lotion that is not.

(Comparative Production Example 3)

A skin lotion was prepared in the same manner as in Preparation Example 3, except that 0.5 wt% of the extract of Example 3 was contained.

(Manufacture example 4)

A skin lotion was prepared in the same manner as in Preparation Example 3, except that the extract of Example 3 contained 1.0 wt%.

(Manufacture example 5)

A skin lotion was prepared in the same manner as in Preparation Example 3, except that the extract of Example 3 contained 30% by weight.

(Comparative Production Example 4)

A skin lotion was prepared in the same manner as in Preparation Example 3, except that the extract of Example 3 contained 35% by weight.

(Test Example 5)

Human body patch test

A human patch test was performed in the same manner as in Test Example 1 except that Preparation Examples 4 and 5 and Comparative Preparation Examples 3 and 4 were used. The results are shown in Table 6 below.

(Test Example 6)

Skin moisturizing effect

The moisturizing effect was measured in the same manner as in Test Example 2, except for using Preparation Examples 4 and 5 and Comparative Preparation Examples 3 and 4 to 20 healthy women (4 groups of 5 people each). The results are shown in Table 7 below.

(Test Example 7)

Antibacterial effect test on skin flora

Except for using Preparation Examples 4 and 5 and Comparative Preparation Examples 3 and 4, the antimicrobial effect was tested in the same manner as in Test Example 3. The results are shown in Table 8 below.

(Test Example 8)

Experiment to improve the recovery speed of damaged skin

Except for using Preparation Examples 4 and 5 and Comparative Preparation Examples 3 and 4, the effect of improving the skin recovery rate was tested in the same manner as in Test Example 4. The results are shown in Table 9 below.

From the results of Tables 6 to 9, when the grown and Edelweiss complex extract is added in less than 1.0% by weight, the skin moisturizing, antimicrobial, and damaged skin improvement effect is insignificant, and when added in excess of 30% by weight is 1.0 to 30 It was found that it is desirable to add weight percent.

As described above, according to the present invention, it is possible to obtain a cosmetic composition containing the overgrown and edelweiss complex extract, which is very excellent in the skin moisturizing effect, antibacterial effect on the skin flora, the effect of improving the speed of damaged skin recovery.

Claims (2)

Cosmetic composition, characterized in that containing 1-30% by weight of the root and edelweiss complex extract of the grown egg. The method of claim 1, The composite extract is a cosmetic composition, characterized in that the extract is a mixture of the root and edelweiss of the grown raw materials in a weight ratio of 9: 1 to 6: 4.