KR100331046B1 - 쇼그렌증후군치료제 - Google Patents
쇼그렌증후군치료제 Download PDFInfo
- Publication number
- KR100331046B1 KR100331046B1 KR1019930012594A KR930012594A KR100331046B1 KR 100331046 B1 KR100331046 B1 KR 100331046B1 KR 1019930012594 A KR1019930012594 A KR 1019930012594A KR 930012594 A KR930012594 A KR 930012594A KR 100331046 B1 KR100331046 B1 KR 100331046B1
- Authority
- KR
- South Korea
- Prior art keywords
- syndrome
- formula
- quinuclidin
- represented
- addition salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4207485A JP2683783B2 (ja) | 1992-07-10 | 1992-07-10 | シェーグレン症候群治療剤 |
| JP92-207485 | 1992-07-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR940005274A KR940005274A (ko) | 1994-03-21 |
| KR100331046B1 true KR100331046B1 (ko) | 2002-08-19 |
Family
ID=16540522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930012594A Expired - Lifetime KR100331046B1 (ko) | 1992-07-10 | 1993-07-06 | 쇼그렌증후군치료제 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5340821A (enExample) |
| EP (1) | EP0578511B1 (enExample) |
| JP (1) | JP2683783B2 (enExample) |
| KR (1) | KR100331046B1 (enExample) |
| AT (1) | ATE184483T1 (enExample) |
| AU (1) | AU666734B2 (enExample) |
| CA (1) | CA2099970C (enExample) |
| DE (1) | DE69326395T2 (enExample) |
| DK (1) | DK0578511T3 (enExample) |
| ES (1) | ES2138613T3 (enExample) |
| IL (1) | IL106218A (enExample) |
| NO (1) | NO303765B1 (enExample) |
| NZ (1) | NZ248099A (enExample) |
| TW (1) | TW230750B (enExample) |
| ZA (1) | ZA934883B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2852608B2 (ja) * | 1994-06-27 | 1999-02-03 | 雪印乳業株式会社 | 口腔乾燥症治療剤 |
| US6140374A (en) * | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
| JP4447685B2 (ja) * | 1999-01-14 | 2010-04-07 | 第一三共株式会社 | 皮膚乾燥症治療剤 |
| JP2006070027A (ja) * | 2004-08-06 | 2006-03-16 | Dai Ichi Seiyaku Co Ltd | 口腔粘膜投与剤 |
| WO2006013914A1 (ja) * | 2004-08-06 | 2006-02-09 | Daiichi Pharmaceutical Co., Ltd. | 口腔粘膜投与剤 |
| JPWO2006038596A1 (ja) * | 2004-10-05 | 2008-05-15 | アステラス製薬株式会社 | 涙液及び唾液乾燥症治療用医薬組成物 |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| US7678363B2 (en) * | 2005-08-26 | 2010-03-16 | Braincells Inc | Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs |
| WO2007047978A2 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134077A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| CA2651813A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| CA2662491A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US8143400B2 (en) * | 2008-01-10 | 2012-03-27 | Apotex Pharmachem Inc. | Process for the preparation and purification of cis-2-methylspiro(1,3-oxathiolane-5,3′)quiniclidine hydrochloride |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| CN102711752B (zh) | 2009-11-12 | 2014-06-18 | 阿卡西亚制药有限公司 | 氨甲酰甲胆碱用于治疗口干燥症的用途 |
| GB201107533D0 (en) | 2011-05-06 | 2011-06-22 | Acacia Pharma Ltd | Formulaiton |
| CN102846607A (zh) * | 2012-04-09 | 2013-01-02 | 珠海亿邦制药股份有限公司 | 一种以盐酸西维美林为活性成分的固体制剂及其应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0314444A2 (en) * | 1987-10-28 | 1989-05-03 | State of IsraelRepresented by the Prime Minister's OfficeThe Israel Institute for Biological Research | Novel oxathiolanes and derivatives thereof, pharmaceutical compositions containing them and the use thereof as medicaments |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001396A (en) * | 1971-08-04 | 1977-01-04 | Chinoin Pharmaceutical And Chemical Works Ltd. | Hormonal product extracted from parathyroid gland and process for the preparation thereof |
| US4110441A (en) * | 1974-04-29 | 1978-08-29 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Gamma-l-glutamyl cholamine phosphate |
| US4100271A (en) * | 1976-02-26 | 1978-07-11 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
| US4701450A (en) * | 1984-03-21 | 1987-10-20 | Akzo N.V. | Steroids for use as immunomodulators |
| US4855290A (en) * | 1985-05-10 | 1989-08-08 | State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research | Derivatives of quinuclidine |
| US4684727A (en) * | 1985-07-29 | 1987-08-04 | Schering Corporation | Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents |
| ZA868369B (en) * | 1986-01-10 | 1987-11-25 | Israel State | Derivatives of quinuclidine |
| GB8717446D0 (en) * | 1987-07-23 | 1987-08-26 | Merck Sharp & Dohme | Chemical compounds |
| CA1303503C (en) * | 1987-11-10 | 1992-06-16 | Marc Plamondon | Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex |
| WO1990005525A1 (en) * | 1988-11-23 | 1990-05-31 | Pfizer Inc. | Quinuclidine derivatives as substance p antagonists |
| US4997654A (en) * | 1989-08-14 | 1991-03-05 | Warner-Lambert Company | Method for increasing salivation for xerostomia patients |
| US5242930A (en) * | 1991-02-11 | 1993-09-07 | Merck Sharp & Dohme Ltd. | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
-
1992
- 1992-07-10 JP JP4207485A patent/JP2683783B2/ja not_active Expired - Lifetime
-
1993
- 1993-07-02 IL IL10621893A patent/IL106218A/xx not_active IP Right Cessation
- 1993-07-06 KR KR1019930012594A patent/KR100331046B1/ko not_active Expired - Lifetime
- 1993-07-06 CA CA002099970A patent/CA2099970C/en not_active Expired - Lifetime
- 1993-07-06 TW TW082105361A patent/TW230750B/zh active
- 1993-07-07 NZ NZ248099A patent/NZ248099A/xx not_active IP Right Cessation
- 1993-07-07 AU AU41819/93A patent/AU666734B2/en not_active Expired
- 1993-07-07 US US08/088,304 patent/US5340821A/en not_active Expired - Lifetime
- 1993-07-07 ZA ZA934883A patent/ZA934883B/xx unknown
- 1993-07-09 NO NO932520A patent/NO303765B1/no not_active IP Right Cessation
- 1993-07-09 AT AT93305423T patent/ATE184483T1/de active
- 1993-07-09 EP EP93305423A patent/EP0578511B1/en not_active Expired - Lifetime
- 1993-07-09 DE DE69326395T patent/DE69326395T2/de not_active Expired - Lifetime
- 1993-07-09 DK DK93305423T patent/DK0578511T3/da active
- 1993-07-09 ES ES93305423T patent/ES2138613T3/es not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0314444A2 (en) * | 1987-10-28 | 1989-05-03 | State of IsraelRepresented by the Prime Minister's OfficeThe Israel Institute for Biological Research | Novel oxathiolanes and derivatives thereof, pharmaceutical compositions containing them and the use thereof as medicaments |
Also Published As
| Publication number | Publication date |
|---|---|
| US5340821A (en) | 1994-08-23 |
| JPH0624981A (ja) | 1994-02-01 |
| DK0578511T3 (da) | 2000-04-03 |
| IL106218A (en) | 1997-02-18 |
| KR940005274A (ko) | 1994-03-21 |
| AU4181993A (en) | 1994-01-13 |
| DE69326395T2 (de) | 2000-04-20 |
| NZ248099A (en) | 1999-07-29 |
| EP0578511A1 (en) | 1994-01-12 |
| IL106218A0 (en) | 1993-11-15 |
| ES2138613T3 (es) | 2000-01-16 |
| ATE184483T1 (de) | 1999-10-15 |
| CA2099970A1 (en) | 1994-01-11 |
| ZA934883B (en) | 1994-02-03 |
| NO932520D0 (no) | 1993-07-09 |
| JP2683783B2 (ja) | 1997-12-03 |
| CA2099970C (en) | 2003-12-30 |
| AU666734B2 (en) | 1996-02-22 |
| DE69326395D1 (de) | 1999-10-21 |
| NO932520L (no) | 1994-01-11 |
| TW230750B (enExample) | 1994-09-21 |
| NO303765B1 (no) | 1998-08-31 |
| EP0578511B1 (en) | 1999-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19930706 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19980423 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19930706 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20000214 Patent event code: PE09021S01D |
|
| AMND | Amendment | ||
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20001030 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20000214 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
|
| AMND | Amendment | ||
| J201 | Request for trial against refusal decision | ||
| PJ0201 | Trial against decision of rejection |
Patent event date: 20001130 Comment text: Request for Trial against Decision on Refusal Patent event code: PJ02012R01D Patent event date: 20001030 Comment text: Decision to Refuse Application Patent event code: PJ02011S01I Appeal kind category: Appeal against decision to decline refusal Decision date: 20011231 Appeal identifier: 2000101002837 Request date: 20001130 |
|
| PB0901 | Examination by re-examination before a trial |
Comment text: Amendment to Specification, etc. Patent event date: 20001130 Patent event code: PB09011R02I Comment text: Request for Trial against Decision on Refusal Patent event date: 20001130 Patent event code: PB09011R01I Comment text: Amendment to Specification, etc. Patent event date: 20000410 Patent event code: PB09011R02I |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20010221 Patent event code: PE09021S01D |
|
| B701 | Decision to grant | ||
| PB0701 | Decision of registration after re-examination before a trial |
Patent event date: 20011231 Comment text: Decision to Grant Registration Patent event code: PB07012S01D Patent event date: 20010129 Comment text: Transfer of Trial File for Re-examination before a Trial Patent event code: PB07011S01I |
|
| N231 | Notification of change of applicant | ||
| PN2301 | Change of applicant |
Patent event date: 20020130 Comment text: Notification of Change of Applicant Patent event code: PN23011R01D |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 20020320 Patent event code: PR07011E01D |
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| PR1002 | Payment of registration fee |
Payment date: 20020320 End annual number: 3 Start annual number: 1 |
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