ES2138613T3 - Derivado de espirooxatiolano-quinuclidina para el tratamiento del sindrome de sjoegren. - Google Patents

Derivado de espirooxatiolano-quinuclidina para el tratamiento del sindrome de sjoegren.

Info

Publication number
ES2138613T3
ES2138613T3 ES93305423T ES93305423T ES2138613T3 ES 2138613 T3 ES2138613 T3 ES 2138613T3 ES 93305423 T ES93305423 T ES 93305423T ES 93305423 T ES93305423 T ES 93305423T ES 2138613 T3 ES2138613 T3 ES 2138613T3
Authority
ES
Spain
Prior art keywords
syndrome
spyrooxatiolane
sjoegren
treatment
quinuclidine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93305423T
Other languages
English (en)
Inventor
Nobuaki Abe
Yasuyoshi Takeshita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16540522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2138613(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Application granted granted Critical
Publication of ES2138613T3 publication Critical patent/ES2138613T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

SE PRESENTA UNA COMPOSICION PARA TRATAR EL SINDROME DE SJOEDREN. LA COMPOSICION COMPRENDE UN DERIVADOS DE ESPIROOXATIOLANO-QUINUCLIDINA DE LA SIGUIENTE FORMULA (/I), DONDE Z ES CR1R2, DONDE R1 Y R2 PUEDEN SER IDENTICOS O DIFERENTES Y CADA UNO REPRESENTA HIDROGENO, ALKILO, CICLOPENTILO, CICLOHEXILO, ARILO, DIARILMETILOL, O ALKILO QUE PUEDE ESTAR SUSTITUIDO POR UNO O MAS GRUPOS ARILO, O UNA SAL DE ADICION DE ACIDO DE ESTOS. ES ESPECIALMENTE EFECTIVO EN UNA ADMISNISTRACION DE UNA SAL DE ADICION DE ACIDO DE 2-METILESPIRO (1,3-OXATIOLANO-5,3'') QUINUCICLIDINA.
ES93305423T 1992-07-10 1993-07-09 Derivado de espirooxatiolano-quinuclidina para el tratamiento del sindrome de sjoegren. Expired - Lifetime ES2138613T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4207485A JP2683783B2 (ja) 1992-07-10 1992-07-10 シェーグレン症候群治療剤

Publications (1)

Publication Number Publication Date
ES2138613T3 true ES2138613T3 (es) 2000-01-16

Family

ID=16540522

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93305423T Expired - Lifetime ES2138613T3 (es) 1992-07-10 1993-07-09 Derivado de espirooxatiolano-quinuclidina para el tratamiento del sindrome de sjoegren.

Country Status (15)

Country Link
US (1) US5340821A (es)
EP (1) EP0578511B1 (es)
JP (1) JP2683783B2 (es)
KR (1) KR100331046B1 (es)
AT (1) ATE184483T1 (es)
AU (1) AU666734B2 (es)
CA (1) CA2099970C (es)
DE (1) DE69326395T2 (es)
DK (1) DK0578511T3 (es)
ES (1) ES2138613T3 (es)
IL (1) IL106218A (es)
NO (1) NO303765B1 (es)
NZ (1) NZ248099A (es)
TW (1) TW230750B (es)
ZA (1) ZA934883B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2852608B2 (ja) * 1994-06-27 1999-02-03 雪印乳業株式会社 口腔乾燥症治療剤
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
JP4447685B2 (ja) * 1999-01-14 2010-04-07 第一三共株式会社 皮膚乾燥症治療剤
US20110150974A1 (en) * 2004-08-06 2011-06-23 Daiichi Pharmaceutical Co., Ltd. Agent For Oral Mucosal Administration
JP2006070027A (ja) * 2004-08-06 2006-03-16 Dai Ichi Seiyaku Co Ltd 口腔粘膜投与剤
KR20070061578A (ko) * 2004-10-05 2007-06-13 아스텔라스세이야쿠 가부시키가이샤 눈물 및 침 건조증 치료용 의약 조성물
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
US7998971B2 (en) 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US8143400B2 (en) * 2008-01-10 2012-03-27 Apotex Pharmachem Inc. Process for the preparation and purification of cis-2-methylspiro(1,3-oxathiolane-5,3′)quiniclidine hydrochloride
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2011058366A1 (en) 2009-11-12 2011-05-19 Acacia Pharma Limited Use of bethanechol for treatment of xerostomia
GB201107533D0 (en) 2011-05-06 2011-06-22 Acacia Pharma Ltd Formulaiton
CN102846607A (zh) * 2012-04-09 2013-01-02 珠海亿邦制药股份有限公司 一种以盐酸西维美林为活性成分的固体制剂及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001396A (en) * 1971-08-04 1977-01-04 Chinoin Pharmaceutical And Chemical Works Ltd. Hormonal product extracted from parathyroid gland and process for the preparation thereof
US4110441A (en) * 1974-04-29 1978-08-29 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. Gamma-l-glutamyl cholamine phosphate
US4100271A (en) * 1976-02-26 1978-07-11 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4701450A (en) * 1984-03-21 1987-10-20 Akzo N.V. Steroids for use as immunomodulators
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
ZA868369B (en) * 1986-01-10 1987-11-25 Israel State Derivatives of quinuclidine
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
US4876260A (en) * 1987-10-28 1989-10-24 State Of Israel, Israel Institute Of Biological Research Oxathiolanes
CA1303503C (en) * 1987-11-10 1992-06-16 Marc Plamondon Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
US4997654A (en) * 1989-08-14 1991-03-05 Warner-Lambert Company Method for increasing salivation for xerostomia patients
ATE154354T1 (de) * 1991-02-11 1997-06-15 Merck Sharp & Dohme Azabicyclische verbindungen, diese enthaltende pharmazeutische zubereitungen und ihre therapeutische verwendung

Also Published As

Publication number Publication date
KR940005274A (ko) 1994-03-21
EP0578511B1 (en) 1999-09-15
JP2683783B2 (ja) 1997-12-03
AU666734B2 (en) 1996-02-22
IL106218A (en) 1997-02-18
US5340821A (en) 1994-08-23
JPH0624981A (ja) 1994-02-01
EP0578511A1 (en) 1994-01-12
NO303765B1 (no) 1998-08-31
NO932520L (no) 1994-01-11
NZ248099A (en) 1999-07-29
AU4181993A (en) 1994-01-13
CA2099970A1 (en) 1994-01-11
DE69326395D1 (de) 1999-10-21
ATE184483T1 (de) 1999-10-15
CA2099970C (en) 2003-12-30
DE69326395T2 (de) 2000-04-20
DK0578511T3 (da) 2000-04-03
NO932520D0 (no) 1993-07-09
KR100331046B1 (ko) 2002-08-19
IL106218A0 (en) 1993-11-15
TW230750B (es) 1994-09-21
ZA934883B (en) 1994-02-03

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