KR100270491B1 - 약제 송출 시스템 및 그의 제조방법 - Google Patents

약제 송출 시스템 및 그의 제조방법 Download PDF

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Publication number
KR100270491B1
KR100270491B1 KR1019930002984A KR930002984A KR100270491B1 KR 100270491 B1 KR100270491 B1 KR 100270491B1 KR 1019930002984 A KR1019930002984 A KR 1019930002984A KR 930002984 A KR930002984 A KR 930002984A KR 100270491 B1 KR100270491 B1 KR 100270491B1
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KR
South Korea
Prior art keywords
parts
weight
granules
coated
minocycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1019930002984A
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English (en)
Korean (ko)
Other versions
KR930019209A (ko
Inventor
니틴베디랄쉐스
조오지프제임즈벨러로오즈쥬니어
키이스앤소니엘웨이
매더레이거루스아미제인슨
키이런조오지무우니
제리베인존슨
Original Assignee
윌리암 에이취 캘넌, 에곤 이 버그
아메리칸사이아나미드컴파니
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Application filed by 윌리암 에이취 캘넌, 에곤 이 버그, 아메리칸사이아나미드컴파니 filed Critical 윌리암 에이취 캘넌, 에곤 이 버그
Publication of KR930019209A publication Critical patent/KR930019209A/ko
Application granted granted Critical
Publication of KR100270491B1 publication Critical patent/KR100270491B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Treatment Devices (AREA)
  • Laser Surgery Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)
KR1019930002984A 1992-03-02 1993-02-27 약제 송출 시스템 및 그의 제조방법 Expired - Lifetime KR100270491B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/844,109 US5262173A (en) 1992-03-02 1992-03-02 Pulsatile once-a-day delivery systems for minocycline
US07/844,109 1992-03-02

Publications (2)

Publication Number Publication Date
KR930019209A KR930019209A (ko) 1993-10-18
KR100270491B1 true KR100270491B1 (ko) 2000-11-01

Family

ID=25291839

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930002984A Expired - Lifetime KR100270491B1 (ko) 1992-03-02 1993-02-27 약제 송출 시스템 및 그의 제조방법

Country Status (24)

Country Link
US (2) US5262173A (OSRAM)
EP (1) EP0558913B1 (OSRAM)
JP (1) JPH069407A (OSRAM)
KR (1) KR100270491B1 (OSRAM)
CN (1) CN1039194C (OSRAM)
AT (1) ATE181504T1 (OSRAM)
AU (1) AU656841B2 (OSRAM)
CA (1) CA2090561C (OSRAM)
CZ (1) CZ283684B6 (OSRAM)
DE (1) DE69325402T2 (OSRAM)
DK (1) DK0558913T3 (OSRAM)
ES (1) ES2134221T3 (OSRAM)
FI (1) FI110163B (OSRAM)
GR (1) GR3031028T3 (OSRAM)
HU (1) HU219580B (OSRAM)
IL (1) IL104865A (OSRAM)
LV (1) LV12399B (OSRAM)
MX (1) MX9300998A (OSRAM)
NO (1) NO307170B1 (OSRAM)
NZ (1) NZ245951A (OSRAM)
PL (1) PL171609B1 (OSRAM)
SG (1) SG47785A1 (OSRAM)
TW (1) TW299235B (OSRAM)
ZA (1) ZA931444B (OSRAM)

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WO1996010996A1 (en) * 1993-07-21 1996-04-18 The University Of Kentucky Research Foundation A multicompartment hard capsule with control release properties
US5538737A (en) * 1994-11-30 1996-07-23 Applied Analytical Industries, Inc. Oral compositions of H2 -antagonists
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ZA974359B (en) * 1996-05-23 1998-05-12 Zeneca Ltd Microencapsulated compositions.
US5932437A (en) * 1998-04-13 1999-08-03 Genesis Laboratories, Inc. Control of lyme disease spirochete
CN1406126A (zh) * 1998-10-01 2003-03-26 诺瓦提斯公司 新型缓释口服制剂
JP2000119181A (ja) 1998-10-06 2000-04-25 Kureha Chem Ind Co Ltd エスクレチン及びその誘導体の放出制御経口製剤
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
CA2348871C (en) * 1998-11-02 2009-04-14 John G. Devane Multiparticulate modified release composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US20050137181A1 (en) * 1999-03-17 2005-06-23 Bonner Ernest L. Method for treatment of reactive arthritis or bursitis
US7691831B2 (en) * 1999-03-17 2010-04-06 Ernest L. Bonner, Jr. Pharmaceutical combination and method for treatment of reactive arthritis or bursitis
US7884090B2 (en) * 1999-03-17 2011-02-08 Ernest L. Bonner, Jr. Compositions and methods for the treatment of arthritis
US6765000B2 (en) * 1999-03-17 2004-07-20 Bonner Jr Ernest L Treatment for reactive arthritis or bursitis
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
JP2002541092A (ja) 1999-04-06 2002-12-03 ファーマクエスト・リミテッド メチルフェニデートのパルス性送達のための薬学的投薬形態
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
ATE526950T1 (de) 1999-10-29 2011-10-15 Euro Celtique Sa Hydrocodon-formulierungen mit gesteuerter freisetzung
IL149282A (en) * 1999-10-29 2010-05-31 Fmc Corp Edible coating composition
EP2283829A1 (en) 2000-10-30 2011-02-16 Euro-Celtique S.A. Controlled release hydrocodone formulations
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
EP1339395A2 (en) 2000-11-28 2003-09-03 Fmc Corporation Edible pga (propylene glycol alginate) coating composition
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
WO2002100381A1 (en) * 2001-06-07 2002-12-19 Tanabe Seiyaku Co., Ltd. Functional grain-containing preparations quickly disintegrated in the oral cavity
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
NZ536273A (en) 2002-12-20 2007-08-31 Hoffmann La Roche High dose ibandronate formulation
CA2894736C (en) 2003-04-07 2019-07-16 Supernus Pharmaceuticals, Inc. Once daily formulations of tetracyclines
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
EP1768668A2 (en) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
JP2008535922A (ja) * 2005-04-12 2008-09-04 エラン・ファルマ・インターナショナル・リミテッド 細菌感染を治療するためのセファロスポリンを含む放出制御組成物
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
WO2007038867A1 (en) * 2005-10-04 2007-04-12 Mistral Pharma Inc. Controlled-release oral dosage form
US20070166273A1 (en) * 2006-01-19 2007-07-19 Krivulka Joseph J Skin treatment educational kit
PT103661B (pt) * 2007-02-23 2010-09-07 Hovione Farmaciencia S A Processo de preparação de minociclina base cristalina
EP2137182A1 (en) * 2007-03-16 2009-12-30 Elan Pharma International Limited Combination of a narcotic and a non-narcotic analgesic
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
CN102014638A (zh) 2007-10-12 2011-04-13 武田制药北美公司 与食物摄入无关的治疗胃肠病症的方法
WO2012145749A1 (en) 2011-04-22 2012-10-26 Napo Pharmaceuticals, Inc. Pharmacologically optimized multimodal drug delivery system for nordihydroguiaretic acid (ndga)
ES2755075T3 (es) 2011-05-05 2020-04-21 Hennig Arzneimittel Gmbh&Co Kg Forma farmacológica para la liberación dirigida de principios activos
DE102011075354A1 (de) * 2011-05-05 2012-11-08 Hennig Arzneimittel Gmbh & Co. Kg Arzneiform zur gezielten Freigabe von Wirkstoffen
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
WO2016162754A1 (en) 2015-04-07 2016-10-13 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for minocycline
CN108414466A (zh) * 2018-03-09 2018-08-17 浙江美华鼎昌医药科技有限公司 一种盐酸米诺环素缓释片体外溶出测定方法
EP3810114A4 (en) * 2018-04-30 2022-01-19 Melinta Therapeutics, Inc. METHODS OF TREATING BACTERIAL INFECTIONS USING ORITAVANCIN

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EP0310814A2 (en) * 1987-10-06 1989-04-12 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
EP0418565A2 (en) * 1989-09-21 1991-03-27 American Cyanamid Company Pulsatile once-a-day delivery system for minocycline

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Also Published As

Publication number Publication date
DE69325402D1 (de) 1999-07-29
GR3031028T3 (en) 1999-12-31
IL104865A0 (en) 1993-06-10
CA2090561A1 (en) 1993-09-03
FI930906A0 (fi) 1993-03-01
PL297903A1 (en) 1993-11-15
NO930743L (no) 1993-09-03
US5262173A (en) 1993-11-16
EP0558913A1 (en) 1993-09-08
CZ30093A3 (en) 1994-02-16
FI930906L (fi) 1993-09-03
CN1078889A (zh) 1993-12-01
ATE181504T1 (de) 1999-07-15
IL104865A (en) 1997-02-18
CZ283684B6 (cs) 1998-06-17
TW299235B (OSRAM) 1997-03-01
SG47785A1 (en) 1998-04-17
AU3384293A (en) 1993-09-09
NZ245951A (en) 1994-06-27
NO307170B1 (no) 2000-02-21
MX9300998A (es) 1993-09-01
PL171609B1 (pl) 1997-05-30
ZA931444B (en) 1993-10-14
LV12399A (lv) 1999-12-20
CN1039194C (zh) 1998-07-22
DK0558913T3 (da) 1999-12-13
ES2134221T3 (es) 1999-10-01
HU219580B (hu) 2001-05-28
LV12399B (en) 2000-06-20
US5348748A (en) 1994-09-20
KR930019209A (ko) 1993-10-18
CA2090561C (en) 2004-10-05
FI110163B (fi) 2002-12-13
NO930743D0 (no) 1993-03-01
DE69325402T2 (de) 2000-02-17
HK1009930A1 (en) 1999-06-11
HU9300570D0 (en) 1993-05-28
HUT64851A (en) 1994-03-28
AU656841B2 (en) 1995-02-16
JPH069407A (ja) 1994-01-18
EP0558913B1 (en) 1999-06-23

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