KR100266305B1 - 아릴기-또는방향족헤테로시클릭기-치환된아미노퀴놀론유도체및항-hiv제 - Google Patents
아릴기-또는방향족헤테로시클릭기-치환된아미노퀴놀론유도체및항-hiv제 Download PDFInfo
- Publication number
- KR100266305B1 KR100266305B1 KR1019930009397A KR930009397A KR100266305B1 KR 100266305 B1 KR100266305 B1 KR 100266305B1 KR 1019930009397 A KR1019930009397 A KR 1019930009397A KR 930009397 A KR930009397 A KR 930009397A KR 100266305 B1 KR100266305 B1 KR 100266305B1
- Authority
- KR
- South Korea
- Prior art keywords
- group
- optionally substituted
- compound
- fluoro
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15891292 | 1992-05-27 | ||
| JP92-158912 | 1992-05-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR930023360A KR930023360A (ko) | 1993-12-18 |
| KR100266305B1 true KR100266305B1 (ko) | 2000-09-15 |
Family
ID=15682065
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930009397A Expired - Fee Related KR100266305B1 (ko) | 1992-05-27 | 1993-05-27 | 아릴기-또는방향족헤테로시클릭기-치환된아미노퀴놀론유도체및항-hiv제 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5519016A (cg-RX-API-DMAC10.html) |
| EP (1) | EP0572259A1 (cg-RX-API-DMAC10.html) |
| KR (1) | KR100266305B1 (cg-RX-API-DMAC10.html) |
| CN (1) | CN1042936C (cg-RX-API-DMAC10.html) |
| AU (1) | AU656859B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2096998A1 (cg-RX-API-DMAC10.html) |
| CZ (1) | CZ99693A3 (cg-RX-API-DMAC10.html) |
| FI (1) | FI932412L (cg-RX-API-DMAC10.html) |
| HU (1) | HUT64051A (cg-RX-API-DMAC10.html) |
| ID (1) | ID20476A (cg-RX-API-DMAC10.html) |
| IL (1) | IL105806A (cg-RX-API-DMAC10.html) |
| MX (1) | MX9303158A (cg-RX-API-DMAC10.html) |
| NO (1) | NO304832B1 (cg-RX-API-DMAC10.html) |
| NZ (1) | NZ247720A (cg-RX-API-DMAC10.html) |
| PH (1) | PH31078A (cg-RX-API-DMAC10.html) |
| RU (1) | RU2124510C1 (cg-RX-API-DMAC10.html) |
| TW (1) | TW234121B (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA933732B (cg-RX-API-DMAC10.html) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4329600A1 (de) * | 1993-09-02 | 1995-03-09 | Bayer Ag | Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate |
| FI970195A7 (fi) * | 1994-07-18 | 1997-02-05 | Ube Industries | Trifluormetyylikinoliinikarboksyylihappojohdannainen |
| DE4425647A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Heterocyclyl-1-phenyl substituierte Chinoloncarbonsäuren |
| DE4425649A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Neue 1-[4-(Aminomethyl)phenyl] substituierte Chinoloncarbonsäuren |
| DE4425660A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 7-substituierte 1-[4-(1H-1,2,4-triazol-1-yl-methyl)phenyl] substituierte Chinoloncarbonsäuren |
| PT793656E (pt) * | 1994-11-24 | 2003-07-31 | Basilea Pharmaceutica Ag | Novas benzil-pirimidinas |
| US5620997A (en) * | 1995-05-31 | 1997-04-15 | Warner-Lambert Company | Isothiazolones |
| DE69623358T2 (de) * | 1995-09-22 | 2003-05-08 | Wakunaga Pharma Co Ltd | Pyridoncarbonsäurederivate als antibakterielle Wirkstoffe |
| US6001863A (en) * | 1996-11-26 | 1999-12-14 | Warner-Lambert Company | Isothiazolones |
| US6387928B1 (en) | 1997-09-15 | 2002-05-14 | The Procter & Gamble Co. | Antimicrobial quinolones, their compositions and uses |
| IL135036A0 (en) | 1997-09-15 | 2001-05-20 | Procter & Gamble | Antimicrobial quinolones, their compositions and uses |
| DE19751948A1 (de) * | 1997-11-24 | 1999-05-27 | Bayer Ag | Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren |
| IL124195A (en) * | 1998-04-23 | 2000-08-31 | Chemagis Ltd | Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid |
| WO2000009472A1 (en) * | 1998-08-12 | 2000-02-24 | Ihara Chemical Industry Co., Ltd. | N-cyclopropyl-2-difluoromethoxy-3-halogenoanilines and intermediates for the preparation thereof |
| PT1140932E (pt) * | 1998-12-21 | 2004-08-31 | Aventis Pharma Sa | Derivados de 1,8-benzonaftiridina |
| DK1262477T3 (da) * | 2000-02-09 | 2008-12-01 | Daiichi Sankyo Co Ltd | Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediens |
| US6514529B2 (en) | 2000-03-22 | 2003-02-04 | Pharmacia & Upjohn Company | Oxazolidinone tablet formulation |
| MY127336A (en) | 2000-03-22 | 2006-11-30 | Upjohn Co | Container for linezolid iv solution |
| US6608078B2 (en) | 2000-05-08 | 2003-08-19 | Wockhardt Limited | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment |
| US7098219B2 (en) | 2000-08-01 | 2006-08-29 | Wockhart Limited | Inhibitors of cellular efflux pumps of microbes |
| AR031135A1 (es) | 2000-10-10 | 2003-09-10 | Upjohn Co | Composiciones de antibiotico topico para el tratamiento de infecciones oculares |
| EP1341781B1 (en) | 2000-12-14 | 2005-09-14 | The Procter & Gamble Company | Antimicrobial quinolones |
| BR0116205A (pt) | 2000-12-14 | 2003-12-23 | Procter & Gamble | 2-piridonas antimicrobianas, suas composições e usos |
| US6878713B2 (en) | 2001-04-25 | 2005-04-12 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
| US6964966B2 (en) | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
| US20040019012A1 (en) * | 2002-02-22 | 2004-01-29 | Singh Satish K. | Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride |
| AU2003213210A1 (en) * | 2002-02-22 | 2003-09-09 | Pharmacia Corporation | Ophthalmic formulation with gum system |
| US6664267B1 (en) | 2002-05-28 | 2003-12-16 | Wockhardt Limited | Crystalline fluoroquinolone arginine salt form |
| EP3406596A1 (en) | 2002-11-20 | 2018-11-28 | Japan Tobacco Inc. | 4-oxoquinoline compound and use thereof as hiv integrase inhibitor |
| WO2006089054A1 (en) * | 2005-02-16 | 2006-08-24 | Achillion Pharmaceuticals, Inc. | New isothiazoloquinolones and related compounds as anti-infective agents |
| TW200510425A (en) * | 2003-08-13 | 2005-03-16 | Japan Tobacco Inc | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor |
| AU2003304460A1 (en) | 2003-09-04 | 2005-03-29 | Wockhardt Limited | Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate |
| ES2232309B1 (es) * | 2003-11-13 | 2006-08-01 | Quimica Sintetica, S.A. | Procedimiento simplificado para la obtencion de gatifloxacino. |
| US7776883B2 (en) * | 2004-03-10 | 2010-08-17 | The United States Of America As Represented By The Department Of Health And Human Services | Quinolin-4-ones as inhibitors of retroviral integrase for the treatment of HIV, AIDS and AIDS related complex (ARC) |
| MY134672A (en) * | 2004-05-20 | 2007-12-31 | Japan Tobacco Inc | Stable crystal of 4-oxoquinoline compound |
| WO2005113509A1 (en) * | 2004-05-20 | 2005-12-01 | Japan Tobacco Inc. | Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor |
| KR100589429B1 (ko) | 2004-08-31 | 2006-06-14 | 한국화학연구원 | Ｎ-1 위치에 아미노피리딜기가 치환된 퀴놀론 유도체의 제조방법 |
| US20090156577A1 (en) * | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| US7732612B2 (en) * | 2004-09-09 | 2010-06-08 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| RU2349586C2 (ru) * | 2004-09-17 | 2009-03-20 | Сайлин Фармасьютикалз, Инк. | Аналоги хинолона |
| JP2008519842A (ja) * | 2004-11-11 | 2008-06-12 | アキリオン ファーマシューティカルズ，インコーポレーテッド | 抗感染剤としての８ａ，９−ジヒドロ−４ａ−ｈ−イソチアゾロ［５，４−ｂ］キノリン−３，４−ジオンおよび関連化合物 |
| US7659399B2 (en) * | 2005-01-05 | 2010-02-09 | Achillion Pharmaceuticals, Inc. | 1-thia-2,4a-diaza-cyclopenta[b]napththalene-3,4-diones and related compounds as anti-infective agents |
| WO2006084053A1 (en) * | 2005-02-02 | 2006-08-10 | Achillion Pharmaceuticals, Inc. | 8-n-substituted-2h-isothiazolo[5,4-b]quinolizine-3,4-diones and related compounds as antiinfective agents |
| BRPI0614456B8 (pt) | 2005-07-27 | 2021-05-25 | Achillion Pharmaceuticals Inc | 8-metoxi-9h-isotiazol[5,4-b]quinolina-3,4-dionas e compostos relacionados como agentes antiinfecciosos |
| JP4669040B2 (ja) * | 2006-03-06 | 2011-04-13 | 日本たばこ産業株式会社 | ４−オキソキノリン化合物の製造方法 |
| MX2008012488A (es) * | 2006-03-28 | 2008-10-10 | Procter & Gamble | Un proceso de acoplamiento para preparar intermedios de quinolona. |
| MX2008012327A (es) * | 2006-03-28 | 2008-10-09 | Procter & Gamble | Un proceso de reduccion con hidruro para preparar intermedios de quinolona. |
| CN101045724B (zh) * | 2006-03-28 | 2011-08-17 | 宝洁公司 | 用于制备喹诺酮中间体的偶联方法 |
| MY148393A (en) | 2006-03-28 | 2013-04-15 | Taigen Biotechnology Co Ltd | Malate salts, and polymorphs of (3s, 5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid |
| US20080318938A1 (en) * | 2007-06-22 | 2008-12-25 | Ryckman David M | Methods for treating aberrant cell proliferation disorders |
| US20080318939A1 (en) * | 2007-06-22 | 2008-12-25 | Whitten Jeffrey P | Methods for treating ophthalmic disorders |
| US7902227B2 (en) * | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
| US8389514B2 (en) * | 2007-09-11 | 2013-03-05 | Kyorin Pharmaceutical Co., Ltd. | Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors |
| JP5373799B2 (ja) | 2007-09-12 | 2013-12-18 | 杏林製薬株式会社 | Ｇｓｋ−３阻害剤としてのスピロ環式アミノキノロン |
| US20090093513A1 (en) * | 2007-10-09 | 2009-04-09 | Hamann Mark T | Method to Use Compositions Having Antidepressant Anxiolytic and Other Neurological Activity and Compositions of Matter |
| US20100273787A1 (en) * | 2007-11-15 | 2010-10-28 | Robert Schwarcz | Kynurenine-aminotransferase inhibitors |
| WO2009089263A2 (en) * | 2008-01-07 | 2009-07-16 | Ardea Biosciences Inc. | Novel compositions and methods of use |
| EA201101451A1 (ru) * | 2009-04-03 | 2012-03-30 | Ачиллион Фармасьютикалз, Инк. | Гидрокситиенохинолоны и родственные соединения как противоинфекционные средства |
| NZ596492A (en) | 2009-05-15 | 2013-08-30 | Redx Pharma Ltd | Redox drug derivatives |
| CN116444491A (zh) * | 2023-03-30 | 2023-07-18 | 浙江工业大学 | 一种喹诺酮类衍生物及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5097032A (en) * | 1984-07-20 | 1992-03-17 | Warner-Lambert Company | Antibacterial agents - II |
| US5210193A (en) * | 1986-01-17 | 1993-05-11 | American Cyanamid Company | Piperazine derivatives |
| US4840956A (en) * | 1986-02-18 | 1989-06-20 | Warner-Lambert Company | Novel disubstituted-7-pyrrolidinoquinoline antibacterial agents |
| DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
| IT1197841B (it) * | 1986-10-14 | 1988-12-06 | Mediolanum Farmaceutici Srl | Derivati pirido-benzotiazinici ad attivita' antibatterica ed a lunga durata di azione |
| JPH0751579B2 (ja) * | 1987-11-07 | 1995-06-05 | 日本新薬株式会社 | キノリンカルボン酸誘導体 |
| EP0470252A4 (en) * | 1989-04-28 | 1992-12-02 | Daiichi Pharmaceutical Co., Ltd. | Anti-hiv drug |
| DE3934082A1 (de) * | 1989-10-12 | 1991-04-18 | Bayer Ag | Chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung als antivirale mittel |
| JPH0754830Y2 (ja) * | 1990-01-24 | 1995-12-18 | 株式会社ユニシアジェックス | 荷重センサ取付構造 |
| KR920004385A (ko) * | 1990-08-09 | 1992-03-27 | 와꾸나가 기스께 | 신규 삼환화합물 또는 그의 염, 이의 제조방법 및 이를 함유하는 항균제 |
| ATE196135T1 (de) * | 1991-05-28 | 2000-09-15 | Daiichi Seiyaku Co | Pyridoncarbonsäurederivate |
-
1993
- 1993-05-24 NO NO931867A patent/NO304832B1/no not_active IP Right Cessation
- 1993-05-25 IL IL105806A patent/IL105806A/en not_active IP Right Cessation
- 1993-05-26 RU RU93035829A patent/RU2124510C1/ru active
- 1993-05-26 FI FI932412A patent/FI932412L/fi unknown
- 1993-05-26 CZ CZ93996A patent/CZ99693A3/cs unknown
- 1993-05-26 CA CA002096998A patent/CA2096998A1/en not_active Abandoned
- 1993-05-26 PH PH46240A patent/PH31078A/en unknown
- 1993-05-26 AU AU39815/93A patent/AU656859B2/en not_active Ceased
- 1993-05-26 TW TW082104157A patent/TW234121B/zh active
- 1993-05-26 HU HU9301536A patent/HUT64051A/hu unknown
- 1993-05-27 KR KR1019930009397A patent/KR100266305B1/ko not_active Expired - Fee Related
- 1993-05-27 NZ NZ247720A patent/NZ247720A/en unknown
- 1993-05-27 MX MX9303158A patent/MX9303158A/es not_active IP Right Cessation
- 1993-05-27 CN CN93108210A patent/CN1042936C/zh not_active Expired - Fee Related
- 1993-05-27 EP EP93304139A patent/EP0572259A1/en not_active Ceased
- 1993-05-27 ZA ZA933732A patent/ZA933732B/xx unknown
- 1993-05-27 ID IDP98154193A patent/ID20476A/id unknown
-
1994
- 1994-11-15 US US08/341,295 patent/US5519016A/en not_active Expired - Fee Related
-
1995
- 1995-09-11 US US08/526,225 patent/US5688791A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1086515A (zh) | 1994-05-11 |
| IL105806A0 (en) | 1993-09-22 |
| ZA933732B (en) | 1993-12-15 |
| NO304832B1 (no) | 1999-02-22 |
| PH31078A (en) | 1998-02-05 |
| HU9301536D0 (en) | 1993-09-28 |
| CA2096998A1 (en) | 1993-11-28 |
| NO931867D0 (no) | 1993-05-24 |
| US5688791A (en) | 1997-11-18 |
| HUT64051A (en) | 1993-11-29 |
| FI932412A7 (fi) | 1993-11-28 |
| ID20476A (id) | 1998-12-24 |
| FI932412L (fi) | 1993-11-28 |
| FI932412A0 (fi) | 1993-05-26 |
| TW234121B (cg-RX-API-DMAC10.html) | 1994-11-11 |
| AU3981593A (en) | 1993-12-02 |
| CN1042936C (zh) | 1999-04-14 |
| NZ247720A (en) | 1994-09-27 |
| NO931867L (no) | 1993-11-29 |
| CZ99693A3 (en) | 1993-12-15 |
| IL105806A (en) | 1998-02-22 |
| AU656859B2 (en) | 1995-02-16 |
| MX9303158A (es) | 1994-04-29 |
| KR930023360A (ko) | 1993-12-18 |
| EP0572259A1 (en) | 1993-12-01 |
| US5519016A (en) | 1996-05-21 |
| RU2124510C1 (ru) | 1999-01-10 |
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