KR100199124B1 - 알파-사슬이 변형된 이소카르바사이클린 및 그 제조법 - Google Patents

알파-사슬이 변형된 이소카르바사이클린 및 그 제조법 Download PDF

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Publication number
KR100199124B1
KR100199124B1 KR1019950701298A KR19950701298A KR100199124B1 KR 100199124 B1 KR100199124 B1 KR 100199124B1 KR 1019950701298 A KR1019950701298 A KR 1019950701298A KR 19950701298 A KR19950701298 A KR 19950701298A KR 100199124 B1 KR100199124 B1 KR 100199124B1
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KR
South Korea
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group
formula
chain
modified
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019950701298A
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English (en)
Korean (ko)
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KR950703511A (ko
Inventor
마사히로 고가
도시오 다나까
다까오 후지
스끼오 마세기
Original Assignee
야스이 쇼사꾸
데이진 가부시키가이샤
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Publication of KR100199124B1 publication Critical patent/KR100199124B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/35—Unsaturated compounds having unsaturation outside the rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019950701298A 1992-10-05 1993-10-01 알파-사슬이 변형된 이소카르바사이클린 및 그 제조법 Expired - Fee Related KR100199124B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP992-266084 1992-10-05
JP26608492 1992-10-05
JP92-266084 1992-10-05
PCT/JP1993/001407 WO1994007838A1 (fr) 1992-10-05 1993-10-01 ISOCARBACYCLINE A CHAINE α MODIFIEE ET PROCEDE POUR SA PRODUCTION

Publications (2)

Publication Number Publication Date
KR950703511A KR950703511A (ko) 1995-09-20
KR100199124B1 true KR100199124B1 (ko) 1999-06-15

Family

ID=17426122

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950701298A Expired - Fee Related KR100199124B1 (ko) 1992-10-05 1993-10-01 알파-사슬이 변형된 이소카르바사이클린 및 그 제조법

Country Status (7)

Country Link
US (1) US5532408A (enExample)
EP (1) EP0664281B1 (enExample)
KR (1) KR100199124B1 (enExample)
AT (1) ATE153652T1 (enExample)
CA (1) CA2146361A1 (enExample)
DE (1) DE69311126T2 (enExample)
WO (1) WO1994007838A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3086595A (en) * 1994-08-09 1996-03-07 Teijin Limited Vascular smooth muscle cell migration inhibitor
WO2023067518A1 (en) * 2021-10-20 2023-04-27 Assembly Biosciences, Inc. Process

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338457A (en) * 1980-02-28 1982-07-06 The Upjohn Company Composition and process
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
JPS62258330A (ja) * 1986-05-01 1987-11-10 Teijin Ltd ６，７−二置換−２−ヒドロキシ−３−メチレンビシクロ〔３．３．０〕オクタン類の製造法
JPH0645575B2 (ja) * 1987-06-04 1994-06-15 帝人株式会社 ３―メチレン―２，６，７―三置換ビシクロ［３．３．０オクタン類
JP3178150B2 (ja) * 1993-03-12 2001-06-18 宇部興産株式会社 採血装置

Also Published As

Publication number Publication date
EP0664281A1 (en) 1995-07-26
KR950703511A (ko) 1995-09-20
DE69311126T2 (de) 1997-11-06
EP0664281B1 (en) 1997-05-28
US5532408A (en) 1996-07-02
EP0664281A4 (enExample) 1995-08-16
CA2146361A1 (en) 1994-04-14
WO1994007838A1 (fr) 1994-04-14
ATE153652T1 (de) 1997-06-15
DE69311126D1 (de) 1997-07-03

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