KR0135608B1 - 티오테파(thiotepa)제조를 위한 에틸렌이민의 개선된 생성방법 - Google Patents

티오테파(thiotepa)제조를 위한 에틸렌이민의 개선된 생성방법

Info

Publication number
KR0135608B1
KR0135608B1 KR1019880017532A KR880017532A KR0135608B1 KR 0135608 B1 KR0135608 B1 KR 0135608B1 KR 1019880017532 A KR1019880017532 A KR 1019880017532A KR 880017532 A KR880017532 A KR 880017532A KR 0135608 B1 KR0135608 B1 KR 0135608B1
Authority
KR
South Korea
Prior art keywords
thiotepa
ethyleneimine
production
temperature
stirring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019880017532A
Other languages
English (en)
Korean (ko)
Other versions
KR890011898A (ko
Inventor
카아잔 존
Original Assignee
알퐁스 아아르 노에
아메리칸 사이아나밋드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알퐁스 아아르 노에, 아메리칸 사이아나밋드 캄파니 filed Critical 알퐁스 아아르 노에
Publication of KR890011898A publication Critical patent/KR890011898A/ko
Application granted granted Critical
Publication of KR0135608B1 publication Critical patent/KR0135608B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564—Three-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019880017532A 1988-01-21 1988-12-26 티오테파(thiotepa)제조를 위한 에틸렌이민의 개선된 생성방법 Expired - Fee Related KR0135608B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7/146.511 1988-01-21
US07/146,511 US4918199A (en) 1988-01-21 1988-01-21 Process for producing thiotepa

Publications (2)

Publication Number Publication Date
KR890011898A KR890011898A (ko) 1989-08-23
KR0135608B1 true KR0135608B1 (ko) 1998-04-23

Family

ID=22517714

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880017532A Expired - Fee Related KR0135608B1 (ko) 1988-01-21 1988-12-26 티오테파(thiotepa)제조를 위한 에틸렌이민의 개선된 생성방법

Country Status (10)

Country Link
US (1) US4918199A (enExample)
EP (1) EP0324920B1 (enExample)
JP (1) JPH021496A (enExample)
KR (1) KR0135608B1 (enExample)
AT (1) ATE111474T1 (enExample)
CA (1) CA1282073C (enExample)
DE (1) DE3851523T2 (enExample)
ES (1) ES2059474T3 (enExample)
FI (1) FI90776C (enExample)
IL (1) IL88453A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561121A (en) * 1993-11-09 1996-10-01 American Cyanamid Company Stable lyophilized thiotepa composition
EP1172651B1 (en) * 2000-02-18 2015-07-15 Panasonic Healthcare Co., Ltd. Measuring system
CN108484669B (zh) * 2018-06-01 2020-07-07 黑龙江福和制药集团股份有限公司 塞替派的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2212146A (en) * 1939-03-10 1940-08-20 Du Pont Preparation of alpha-alkylenimines, e. g., ethylenimine
US2670347A (en) * 1952-01-08 1954-02-23 American Cyanamid Co Thiophosphoric acid derivatives and method of preparing the same

Also Published As

Publication number Publication date
US4918199A (en) 1990-04-17
FI890309L (fi) 1989-07-22
EP0324920A2 (en) 1989-07-26
KR890011898A (ko) 1989-08-23
IL88453A0 (en) 1989-06-30
JPH0579075B2 (enExample) 1993-11-01
DE3851523T2 (de) 1995-03-16
EP0324920B1 (en) 1994-09-14
FI890309A0 (fi) 1989-01-20
EP0324920A3 (en) 1990-10-31
FI90776C (fi) 1994-03-25
IL88453A (en) 1993-01-14
FI90776B (fi) 1993-12-15
DE3851523D1 (de) 1994-10-20
ATE111474T1 (de) 1994-09-15
JPH021496A (ja) 1990-01-05
CA1282073C (en) 1991-03-26
ES2059474T3 (es) 1994-11-16

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