ES2059474T3 - Procedimiento perfeccionado para producir thiotepa. - Google Patents
Procedimiento perfeccionado para producir thiotepa.Info
- Publication number
- ES2059474T3 ES2059474T3 ES88119469T ES88119469T ES2059474T3 ES 2059474 T3 ES2059474 T3 ES 2059474T3 ES 88119469 T ES88119469 T ES 88119469T ES 88119469 T ES88119469 T ES 88119469T ES 2059474 T3 ES2059474 T3 ES 2059474T3
- Authority
- ES
- Spain
- Prior art keywords
- thiotepa
- producing
- perfected procedure
- perfected
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FOCVUCIESVLUNU-UHFFFAOYSA-N Thiotepa Chemical compound C1CN1P(N1CC1)(=S)N1CC1 FOCVUCIESVLUNU-UHFFFAOYSA-N 0.000 title 1
- 229960001196 thiotepa Drugs 0.000 title 1
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
ESTE DESCUBRIMIENTO DESCRIBE UN PROCESO MEJORADO PARA PREPARAR N, N'', N'''' TRIETILENOTIOFOSFORAMIDA POR LA GENERACION IN SITU DE ETILENOIMINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/146,511 US4918199A (en) | 1988-01-21 | 1988-01-21 | Process for producing thiotepa |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2059474T3 true ES2059474T3 (es) | 1994-11-16 |
Family
ID=22517714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88119469T Expired - Lifetime ES2059474T3 (es) | 1988-01-21 | 1988-11-23 | Procedimiento perfeccionado para producir thiotepa. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4918199A (es) |
EP (1) | EP0324920B1 (es) |
JP (1) | JPH021496A (es) |
KR (1) | KR0135608B1 (es) |
AT (1) | ATE111474T1 (es) |
CA (1) | CA1282073C (es) |
DE (1) | DE3851523T2 (es) |
ES (1) | ES2059474T3 (es) |
FI (1) | FI90776C (es) |
IL (1) | IL88453A (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5561121A (en) * | 1993-11-09 | 1996-10-01 | American Cyanamid Company | Stable lyophilized thiotepa composition |
EP1172651B1 (en) * | 2000-02-18 | 2015-07-15 | Panasonic Healthcare Co., Ltd. | Measuring system |
CN108484669B (zh) * | 2018-06-01 | 2020-07-07 | 黑龙江福和制药集团股份有限公司 | 塞替派的制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2212146A (en) * | 1939-03-10 | 1940-08-20 | Du Pont | Preparation of alpha-alkylenimines, e. g., ethylenimine |
US2670347A (en) * | 1952-01-08 | 1954-02-23 | American Cyanamid Co | Thiophosphoric acid derivatives and method of preparing the same |
-
1988
- 1988-01-21 US US07/146,511 patent/US4918199A/en not_active Expired - Lifetime
- 1988-11-22 IL IL88453A patent/IL88453A/xx not_active IP Right Cessation
- 1988-11-23 ES ES88119469T patent/ES2059474T3/es not_active Expired - Lifetime
- 1988-11-23 EP EP88119469A patent/EP0324920B1/en not_active Expired - Lifetime
- 1988-11-23 AT AT88119469T patent/ATE111474T1/de not_active IP Right Cessation
- 1988-11-23 DE DE3851523T patent/DE3851523T2/de not_active Expired - Fee Related
- 1988-12-26 KR KR1019880017532A patent/KR0135608B1/ko not_active IP Right Cessation
-
1989
- 1989-01-18 JP JP1007904A patent/JPH021496A/ja active Granted
- 1989-01-19 CA CA000588625A patent/CA1282073C/en not_active Expired - Fee Related
- 1989-01-20 FI FI890309A patent/FI90776C/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0324920A2 (en) | 1989-07-26 |
IL88453A (en) | 1993-01-14 |
ATE111474T1 (de) | 1994-09-15 |
IL88453A0 (en) | 1989-06-30 |
JPH0579075B2 (es) | 1993-11-01 |
KR0135608B1 (ko) | 1998-04-23 |
FI90776B (fi) | 1993-12-15 |
FI890309A0 (fi) | 1989-01-20 |
DE3851523D1 (de) | 1994-10-20 |
EP0324920A3 (en) | 1990-10-31 |
DE3851523T2 (de) | 1995-03-16 |
KR890011898A (ko) | 1989-08-23 |
JPH021496A (ja) | 1990-01-05 |
EP0324920B1 (en) | 1994-09-14 |
FI90776C (fi) | 1994-03-25 |
CA1282073C (en) | 1991-03-26 |
FI890309A (fi) | 1989-07-22 |
US4918199A (en) | 1990-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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