ES2144995T3 - Preparacion de derivados de indol. - Google Patents

Preparacion de derivados de indol.

Info

Publication number
ES2144995T3
ES2144995T3 ES91305602T ES91305602T ES2144995T3 ES 2144995 T3 ES2144995 T3 ES 2144995T3 ES 91305602 T ES91305602 T ES 91305602T ES 91305602 T ES91305602 T ES 91305602T ES 2144995 T3 ES2144995 T3 ES 2144995T3
Authority
ES
Spain
Prior art keywords
preparation
indol
derivatives
acid
methylbenzenemethanesulphonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91305602T
Other languages
English (en)
Inventor
Frederick David Albinson
Derek Leslie Crookes
John Wilson Macfarla Mackinnon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ES2144995T3 publication Critical patent/ES2144995T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

UN METODO PARA LA PREPARACION DE 3-(2-AMINOETIL)-N-METIL-1H-INDOL-5-METANOSULFONAMIDA HACIENDO REACCIONAR 4-HIDRAZINO-N-METILBENCENOMETANOSULFONAMIDA Y ACIDO 4-CLORO-1-HIDROXIBUTANOSULFONICO, SAL SODICA EN PRESENCIA DE UN ACIDO.
ES91305602T 1990-06-21 1991-06-20 Preparacion de derivados de indol. Expired - Lifetime ES2144995T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909013845A GB9013845D0 (en) 1990-06-21 1990-06-21 Process

Publications (1)

Publication Number Publication Date
ES2144995T3 true ES2144995T3 (es) 2000-07-01

Family

ID=10677976

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91305602T Expired - Lifetime ES2144995T3 (es) 1990-06-21 1991-06-20 Preparacion de derivados de indol.

Country Status (8)

Country Link
US (1) US5103020A (es)
EP (1) EP0462837B1 (es)
JP (1) JP3166125B2 (es)
AT (1) ATE191476T1 (es)
DE (1) DE69132091T2 (es)
DK (1) DK0462837T3 (es)
ES (1) ES2144995T3 (es)
GB (1) GB9013845D0 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
EP1572647B1 (en) 2002-12-20 2016-09-21 Basf Se Synthesis of amines and intermediates for the synthesis thereof
US7375219B2 (en) * 2005-04-13 2008-05-20 Neuraxon, Inc. Substituted indole compounds having NOS inhibitory activity
TW200808780A (en) * 2006-04-13 2008-02-16 Neuraxon Inc 1,5 and 3,6- substituted indole compounds having NOS inhibitory activity
CN100554252C (zh) * 2007-07-17 2009-10-28 浙江苏泊尔制药有限公司 一种琥珀酸舒马曲坦的制备方法
US20090131503A1 (en) * 2007-11-16 2009-05-21 Annedi Subhash C 3,5 - substituted indole compounds having nos and norepinephrine reuptake inhibitory activity
BRPI0820632A2 (pt) * 2007-11-16 2015-06-16 Neuraxon Inc Compostos de indol e métodos para tratamento de dor visceral
WO2009064505A1 (en) * 2007-11-16 2009-05-22 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating visceral pain
CN102432519B (zh) * 2011-11-21 2013-12-11 山东新华制药股份有限公司 3-(2-氨乙基)-n-甲基-1h-吲哚-5-甲烷磺酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55105664A (en) * 1979-02-08 1980-08-13 Kawaken Fine Chem Co Ltd Preparation of tryptamine
GR79215B (es) * 1982-06-07 1984-10-22 Glaxo Group Ltd
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds

Also Published As

Publication number Publication date
JPH04230258A (ja) 1992-08-19
GB9013845D0 (en) 1990-08-15
US5103020A (en) 1992-04-07
DE69132091T2 (de) 2000-10-12
ATE191476T1 (de) 2000-04-15
EP0462837A3 (en) 1992-09-23
DK0462837T3 (da) 2000-09-11
JP3166125B2 (ja) 2001-05-14
EP0462837B1 (en) 2000-04-05
DE69132091D1 (de) 2000-05-11
EP0462837A2 (en) 1991-12-27

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